colforsin has been researched along with adenosine diphosphate in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (20.83) | 18.7374 |
1990's | 39 (54.17) | 18.2507 |
2000's | 12 (16.67) | 29.6817 |
2010's | 6 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Heemskerk, JW; Sage, SO | 1 |
Boulanger, CM; Vanhoutte, PM | 1 |
Classen, M; Offermanns, S; Rosenthal, W; Schepp, W; Schmidtler, J; Schusdziarra, V | 1 |
Imaizumi, T; Iwakura, K; Iwasaki, T; Kawamoto, H; Morita, H; Sakagoshi, N; Watanabe, Y; Yoshida, H | 1 |
Buzzi, E; Colao, C; Leoncini, G; Maresca, M; Mazzei, M | 1 |
Iizuka, H; Tsutsui, M | 1 |
Heppel, LA; Huang, NN; Wang, DJ | 1 |
Goldstein, M; Harada, K; Meller, E | 1 |
Dewey, J; Schini, VB; Vanhoutte, PM | 1 |
Kamiya, K; Kodama, I; Sugiura, H; Toyama, J; Tsuboi, N | 1 |
Belisle, S; Bellabarba, D; Gallo-Payet, N; Guillon, G; Lehoux, JG; Pantaloni, C; Petit, A; Tence, M | 1 |
Reast, R; Rink, TJ; Sage, SO | 1 |
Haslam, RJ; Murphy, W; Williams, KA | 1 |
Faul, C; Jaschonek, K; Renn, W; Schmidt, H | 1 |
Baughman, KL; Cates, AE; Feldman, AM; Levine, MA; Van Dop, C | 1 |
Gierschik, P; Jakobs, KH; Reithmann, C; Sidiropoulos, D; Werdan, K | 1 |
Clark, RB; Friedman, J; Kunkel, MW; Shenolikar, S | 1 |
Balestre, MN; Guillon, G; Kirk, CJ; Lombard, C; Rassendren, F | 1 |
Gonçalves, ML; Ribeiro, JA | 1 |
Bühler, FR; Dimitrov, D; Resink, TJ; Stucki, S | 1 |
Evans, RM; Guccione, MA; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Perry, DW; Rand, ML | 1 |
Fredholm, BB; Li, YO | 1 |
Hamid, S; Whittle, BJ | 1 |
Kariya, T; Morito, F; Sakai, T; Takahata, K; Yamanaka, M | 1 |
Rink, TJ; Sage, SO | 1 |
Feinstein, MB; Zavoico, GB | 1 |
Adnot, S; Desmier, M; Ferry, N; Hanoune, J; Sevenet, T | 1 |
Carmena, MJ; García-Paramio, P; Prieto, JC; Solano, RM | 1 |
Bernabei, A; Edmunds, LH; Gikakis, N; Kowalska, MA; Niewiarowski, S | 1 |
Chang, K; Hanaoka, K; Kumada, M; Takuwa, Y | 1 |
Cobbold, PH; Dixon, CJ; Green, AK | 2 |
Akaike, N; Kawa, K; Uneyama, H; Yamashita, Y | 1 |
Arilla, E; Guijarro, LG; López-Sañudo, S; Prieto, JC; Puebla, L | 1 |
Hönig-Liedl, P; Horstrup, K; Jablonka, B; Just, M; Kochsiek, K; Walter, U | 1 |
Arilla, E; Carrero, I; Couvineau, A; Guijarro, LG; Laburthe, M; Prieto, JC; Rodriguez-Henche, N | 1 |
Classen, M; Dehne, K; Offermanns, S; Rosenthal, W; Schepp, W; Schmidtler, J | 1 |
Detimary, P; Gao, ZY; Gembal, M; Gilon, P; Henquin, JC | 1 |
Consiglio, E; Di Jeso, B; Formisano, S; Laviola, L; Liguoro, D | 1 |
Ghate, AV; Linz, W; Rajagopalan, R; Schoelkens, BA; Subbarayan, P | 1 |
Betteridge, DJ; Cooper, MB; Gasser, JA; Saggerson, ED; Tan, KC | 1 |
Figarella, C; Merten, M; Montserrat, C | 1 |
Fein, A; Kapural, L | 1 |
Kozlik-Feldmann, R; Netz, H; Pilz, G; Reber, D; Reithmann, C; Welz, A; Werdan, K | 1 |
Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR | 1 |
Franklin, A; Hariawala, MD; Li, J; Sellke, FW; Stamler, A; Tofukuji, M | 1 |
Bobbin, RP; Chen, C | 1 |
Glenn, JR; Heptinstall, S | 1 |
Holmsen, H; Olav Jensen, B; Ryningen, A | 1 |
Holmsen, H; Ryningen, A | 1 |
Dhalla, NS; Elimban, V; Persad, S; Siddiqui, F | 1 |
Chapman, J; Mader, SL; Schutzer, WE; Watts, VJ | 1 |
Habuchi, Y; Morikawa, J; Nishio, M; Tanaka, H; Yamamoto, T | 1 |
Hourani, SM; Pearson, A; Tennant, JP | 1 |
Kosaka, H; Yoneyama, H; Zhou, MS | 1 |
Altmann, C; Haude, M; Hermann, BL; Mann, K; Naber, C; Rosskopf, D; Siffert, W; Vietzke, D | 1 |
Bilbe, G; Bowler, WB; Buckley, KA; Gallagher, JA; Gaw, A; Hipskind, RA; McKay, G; Wagstaff, SC | 1 |
Koksch, M; Pfeiffer, D; Ruehlmann, C; Woinke, M; Zeiger, F | 1 |
Bukharaeva, EA; Nikolsky, E; Samigullin, D; Vyskocil, F | 1 |
Aitken, A; Flynn, G; Mitchell, M; Patel, K; Patel, YM; Rahman, S; Savidge, G; Smith, MP; Spooner, G; Sumathipala, R | 1 |
Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
Ishikawa, T; Ito, Y; Kondo, M; Kume, H; Nakayama, S; Sato, S; Shimokata, K; Son, M | 1 |
Krishnamurthy, G; Smith, D; Tawa, G; Wang, Y; Young, KH | 1 |
Ilan, N; Shafat, I; Vlodavsky, I | 1 |
Adams, DJ; Bartlett, PF; Stafford, MR | 1 |
Baqi, Y; Glänzel, M; Hoffmann, K; Morena, MS; Müller, CE; von Kügelgen, I | 1 |
Laychock, SG; You, H | 1 |
Gartner, TK; Li, Z; Morris, AJ; Ren, H; Smyth, SS; Sunkara, M; Xiang, B; Zhang, G | 1 |
Baqi, Y; Hoffmann, K; Lutz, DA; Müller, CE; Straßburger, J; von Kügelgen, I | 1 |
Gurgul-Convey, E; Kaminski, MT; Lenzen, S | 1 |
Aungraheeta, R; Butler, M; Conibear, A; Kelly, E; Mumford, A; Mundell, SJ; Nylander, S | 1 |
Bertoldo, MJ; Bustamante, S; Gilchrist, RB; Kanakkaparambil, R; Lavea, CF; Richani, D; Riepsamen, AH | 1 |
1 trial(s) available for colforsin and adenosine diphosphate
Article | Year |
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Changes in signal transduction in the platelets of patients with peripheral occlusive arterial disease.
Topics: Adenosine Diphosphate; Arterial Occlusive Diseases; Blood Platelets; Colforsin; Enzyme Inhibitors; Estrenes; Female; Flow Cytometry; Humans; In Vitro Techniques; Indoles; Male; Maleimides; Middle Aged; P-Selectin; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Proteins; Pyrrolidinones; Receptors, Thrombin; Second Messenger Systems; Signal Transduction | 2000 |
71 other study(ies) available for colforsin and adenosine diphosphate
Article | Year |
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Thromboxane receptor stimulation inhibits adenylate cyclase and reduces cyclic AMP-mediated inhibition of ADP-evoked responses in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Alprostadil; Calcium; Colforsin; Cyclic AMP; Fura-2; Humans; Manganese; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2 | 1992 |
Cholera toxin augments the release of endothelium-derived relaxing factor evoked by bradykinin and the calcium ionophore A23187.
Topics: Adenosine Diphosphate; Animals; Bradykinin; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Nitric Oxide; Swine | 1992 |
Pertussis toxin reverses prostaglandin E2- and somatostatin-induced inhibition of rat parietal cell H(+)-production.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Aminopyrine; Animals; Colforsin; Dinoprostone; Female; GTP-Binding Proteins; Histamine; Parietal Cells, Gastric; Pertussis Toxin; Protons; Rats; Rats, Inbred Strains; Somatostatin; Virulence Factors, Bordetella | 1992 |
Effects of lithium ion on the inhibitory GTP-binding protein and its coupling response.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Centrifugation, Density Gradient; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Lithium; Magnesium; Pertussis Toxin; Receptors, Adrenergic, alpha; Ribose; Virulence Factors, Bordetella | 1991 |
Mode of action of 2-(diethylamino)-7-ethoxychromone on human platelets.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Chromones; Colforsin; Collagen; Cyclic AMP; Humans; Iloprost; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2 | 1991 |
Inhibitory guanine nucleotide binding protein in pig epidermis: regulation of epidermal adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epidermis; GTP-Binding Proteins; Pertussis Toxin; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Imidodiphosphate; Animals; Cells, Cultured; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Epidermal Growth Factor; Insulin; Keratinocytes; Kinetics; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Platelet-Derived Growth Factor; Thymidine; Transforming Growth Factors; Tritium; Vasoactive Intestinal Peptide; Wound Healing | 1990 |
Effects of pertussis toxin on inhibition of synaptosomal tyrosine hydroxylase activity by apomorphine.
Topics: Adenosine Diphosphate; Animals; Apomorphine; Colforsin; GTP-Binding Proteins; In Vitro Techniques; Male; NAD; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptosomes; Tyrosine 3-Monooxygenase; Virulence Factors, Bordetella | 1990 |
Effects of indapamide on endothelium-dependent relaxations in isolated canine femoral arteries.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Bradykinin; Calcimycin; Colforsin; Dinoprost; Diuretics; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Femoral Artery; Indapamide; Indomethacin; Male; Nitric Oxide; Vasodilation | 1990 |
ATP directly affects junctional conductance between paired ventricular myocytes isolated from guinea pig heart.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Cell Separation; Colforsin; Cyclic AMP; Electric Conductivity; Heart Ventricles; Intercellular Junctions; Myocardium; Osmolar Concentration; Temperature | 1990 |
An islet-activating protein-sensitive G-protein is involved in dopamine inhibition of both angiotensin-stimulated inositol phosphate production and human placental lactogen release in human trophoblastic cells.
Topics: Adenosine Diphosphate; Angiotensin II; Calcium; Cell Membrane; Colforsin; Cyclic AMP; Dopamine; Female; GTP-Binding Proteins; Humans; Inositol Phosphates; Pertussis Toxin; Placental Lactogen; Pregnancy; Trophoblasts; Virulence Factors, Bordetella | 1990 |
ADP evokes biphasic Ca2+ influx in fura-2-loaded human platelets. Evidence for Ca2+ entry regulated by the intracellular Ca2+ store.
Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium; Cells, Cultured; Colforsin; Fluorescent Dyes; Fura-2; Humans; Imidazoles; Kinetics; Manganese; Temperature | 1990 |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epinephrine; Humans; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Desensitization of platelets to iloprost. Loss of specific binding sites and heterologous desensitization of adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Cardiovascular Agents; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epoprostenol; Humans; Iloprost; In Vitro Techniques; Kinetics; Phosphorus Radioisotopes; Ribose | 1988 |
Multiple effects of ethanol on cardiac adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Ethanol; Female; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Iodocyanopindolol; Isoproterenol; Male; Manganese; Myocardium; NAD; Pindolol; Rabbits; Receptors, Adrenergic, beta | 1989 |
Mechanism of noradrenaline-induced heterologous desensitization of adenylate cyclase stimulation in rat heart muscle cells: increase in the level of inhibitory G-protein alpha-subunits.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Heart; Immunoblotting; Myocardium; Norepinephrine; Pertussis Toxin; Rats; Virulence Factors, Bordetella | 1989 |
Cell-free heterologous desensitization of adenylyl cyclase in S49 lymphoma cell membranes mediated by cAMP-dependent protein kinase.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alprostadil; Cell Line; Cell Membrane; Cell-Free System; Colforsin; Enzyme Activation; Epinephrine; In Vitro Techniques; Lymphoma; Protein Kinases; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1989 |
Influence of bacterial toxins and forskolin upon vasopressin-induced inositol phosphate accumulation in WRK 1 cells.
Topics: Adenosine Diphosphate; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Inositol Phosphates; Mammary Neoplasms, Experimental; Pertussis Toxin; Rats; Receptors, Angiotensin; Receptors, Vasopressin; Tumor Cells, Cultured; Vasopressins; Virulence Factors, Bordetella | 1989 |
Effects of purines and forskolin on haemolysis.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anesthetics, Local; Animals; Bucladesine; Chlorpromazine; Colforsin; Edetic Acid; Hemolysis; In Vitro Techniques; Polyphosphates; Procaine; Purines; Rats; Xanthines | 1987 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Effects on the buoyant density of rabbit platelets of ADP and agents that increase the concentration of cyclic AMP.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Bucladesine; Centrifugation, Density Gradient; Colforsin; Cyclic AMP; Cytoplasmic Granules; Diterpenes; Edetic Acid; Glycoproteins; Papaverine; Polylysine; Rabbits; Time Factors | 1985 |
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Microcirculation; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1985 |
Interaction of prostaglandin D2 with prostacyclin, carbacyclin and the hydantoin prostaglandin, BW245C, in guinea-pig platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Bucladesine; Colforsin; Diterpenes; Drug Interactions; Epoprostenol; Guinea Pigs; Hydantoins; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin D2; Prostaglandins D | 1985 |
Effect of forskolin on platelet deaggregation and cyclic AMP generation.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Collagen; Cyclic AMP; Drug Synergism; Epoprostenol; Humans; In Vitro Techniques; Phosphorylation; Platelet Aggregation; Proteins | 1985 |
The kinetics of changes in intracellular calcium concentration in fura-2-loaded human platelets.
Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium; Colforsin; Dose-Response Relationship, Drug; Egtazic Acid; Fluorometry; Fura-2; Humans; Kinetics; Nickel; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Thrombin; Vasopressins | 1987 |
Cytoplasmic Ca2+ in platelets is controlled by cyclic AMP: antagonism between stimulators and inhibitors of adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Blood Platelets; Calcium; Colforsin; Cyclic AMP; Diterpenes; Epinephrine; Epoprostenol; Humans; Prostaglandin D2; Prostaglandins D; Thrombin | 1984 |
Forskolin (a powerful inhibitor of human platelet aggregation).
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Biotransformation; Calcimycin; Cell Membrane; Colforsin; Diterpenes; Epinephrine; Humans; In Vitro Techniques; Platelet Aggregation | 1982 |
Protein kinase C regulation of the adenylyl cyclase system in rat prostatic epithelium.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Guanylyl Imidodiphosphate; Isoproterenol; Male; Neuropeptides; Neurotransmitter Agents; Pertussis Toxin; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Prostate; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1995 |
Iloprost and echistatin protect platelets during simulated extracorporeal circulation.
Topics: Adenosine Diphosphate; beta-Thromboglobulin; Blood Platelets; Cardiopulmonary Bypass; Colforsin; Cyclic AMP; Epinephrine; Humans; Iloprost; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Oligopeptides; Peptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Viper Venoms | 1995 |
Molecular cloning and functional analysis of a novel P2 nucleotide receptor.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenylate Cyclase Toxin; Amino Acid Sequence; Animals; Aorta; Base Sequence; Blotting, Northern; Calcium; Cells, Cultured; Chickens; Cloning, Molecular; Colforsin; Cyclic AMP; DNA, Complementary; Gene Library; Glioma; Inositol Phosphates; Kidney; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligodeoxyribonucleotides; Organ Specificity; Pertussis Toxin; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Cytosolic free Ca2+ oscillations induced by diadenosine 5',5"'-P1,P3-triphosphate and diadenosine 5',5"'-P1,P4-tetraphosphate in single rat hepatocytes are indistinguishable from those induced by ADP and ATP respectively.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Dinucleoside Phosphates; Diterpenes; Kinetics; Liver; Male; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Time Factors | 1995 |
Existence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Bone Marrow Cells; Calcimycin; Calcium Channels; Colforsin; Cyclic AMP; Electrophysiology; Female; In Vitro Techniques; Inosine Triphosphate; Isoquinolines; Male; Megakaryocytes; Nystatin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram | 1993 |
Alpha-2 adrenoceptors modulate the somatostatinergic system and G protein levels in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Clonidine; Colforsin; GTP-Binding Proteins; Hippocampus; Kinetics; Male; Membranes; Pertussis Toxin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Somatostatin; Virulence Factors, Bordetella; Yohimbine | 1995 |
Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Blood Proteins; Cell Adhesion Molecules; Colforsin; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; In Vitro Techniques; Kinetics; Membrane Proteins; Microfilament Proteins; Molsidomine; Nitroprusside; Phosphoproteins; Phosphoserine; Platelet Membrane Glycoproteins; Protein Kinases; Protein-Tyrosine Kinases; Serine; Vasodilator Agents | 1994 |
G proteins in rat liver proliferation during cholestasis.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bile Ducts; Cell Division; Cell Membrane; Cholera Toxin; Cholestasis; Colforsin; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Ligation; Liver; Male; Peptide Fragments; Pertussis Toxin; Rats; Rats, Wistar; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1994 |
Elevated intracellular cyclic AMP exerts different modulatory effects on cytosolic free Ca2+ oscillations induced by ADP and ATP in single rat hepatocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cytosol; Diterpenes; In Vitro Techniques; Liver; Male; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Purinergic | 1994 |
Stimulation of rat parietal cell function by histamine and GLP-1-(7-36) amide is mediated by Gs alpha.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Aminopyrine; Animals; Cell Membrane; Cell Separation; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; GTP-Binding Proteins; Histamine; Kinetics; Molecular Weight; Parietal Cells, Gastric; Peptide Fragments; Rats; Rats, Wistar | 1994 |
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
P2 purinergic agonists and 12-O-tetradecanoylphorbol-13-acetate, as well as protein kinase A activators, stimulate thyroglobulin secretion in FRTL-5 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenosine Triphosphate; Cells, Cultured; Colforsin; Enzyme Activation; Guanosine Triphosphate; Protein Kinases; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroglobulin | 1993 |
Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one.
Topics: Adenosine Diphosphate; Anesthesia; Animals; Cardiotonic Agents; Cats; Colforsin; Cricetinae; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Heart Failure; Ileum; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Male; Mesocricetus; Muscle, Smooth; Myocardial Reperfusion Injury; Papillary Muscles; Platelet Aggregation; Propranolol; Rats; Rats, Wistar; Regional Blood Flow | 1993 |
Altered cellular signalling and decreased platelet sensitivity to adenosine in insulin-dependent diabetic patients with proliferative retinopathy.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Blood Platelets; Cell Membrane; Colforsin; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Epoprostenol; Female; GTP-Binding Proteins; Humans; Middle Aged; Platelet Aggregation; Receptors, Purinergic; Signal Transduction | 1993 |
Defective ATP-dependent mucin secretion by cystic fibrosis pancreatic epithelial cells.
Topics: Adenocarcinoma; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Antigens; Calcium; Carbachol; Cell Line; Colforsin; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelium; Humans; Immunoassay; Mucins; Pancreatic Neoplasms; Receptors, Purinergic P2; Transfection; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
Suppression of the voltage-gated K+ current of human megakaryocytes by thrombin and prostacyclin.
Topics: 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Bone Marrow; Colforsin; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Epoprostenol; GTP-Binding Proteins; Humans; Ion Channel Gating; Megakaryocytes; Membrane Potentials; Patch-Clamp Techniques; Peptide Fragments; Peptides; Platelet Aggregation Inhibitors; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Receptors, Thrombin; Thrombin; Thromboxane A2 | 1997 |
A post-receptor defect of adenylyl cyclase in severely failing myocardium from children with congenital heart disease.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adolescent; Cell Membrane; Child; Child, Preschool; Colforsin; Female; GTP-Binding Proteins; Heart Atria; Heart Defects, Congenital; Heart Failure; Humans; Infant, Newborn; Male; Myocardium; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Comparative effects of continuous warm blood and intermittent cold blood cardioplegia on coronary reactivity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blood; Calcimycin; Colforsin; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Guanidines; Heart Arrest, Induced; In Vitro Techniques; Isoproterenol; Microcirculation; Pinacidil; Potassium Channels; Swine; Temperature; Vasodilation; Vasodilator Agents | 1997 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Iloprost; Magnesium; Platelet Aggregation Inhibitors; Platelet Count; Quinazolines; Receptors, Purinergic P2; Reference Values | 1998 |
Elevation of cyclic AMP decreases phosphoinositide turnover and inhibits thrombin-induced secretion in human platelets.
Topics: Adenine; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Kinetics; Phosphates; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorus Radioisotopes; Signal Transduction; Thrombin; Type C Phospholipases | 1998 |
Role of autocrine stimulation for the effects of cyclic AMP on protein and lipid phosphorylation in platelets activated by particles.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Blood Proteins; Colforsin; Contrast Media; Cyclic AMP; Cytoplasmic Granules; Fat Emulsions, Intravenous; Humans; In Vitro Techniques; Lipids; Lysosomes; Metrizoic Acid; Phosphates; Phospholipids; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet Activation; Protein Kinase C; Serum Albumin | 1998 |
Alterations in cardiac membrane beta-adrenoceptors and adenylyl cyclase due to hypochlorous acid.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Cholera Toxin; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypochlorous Acid; Immunoblotting; Isoproterenol; Lipid Peroxidation; Methionine; Myocardium; Pertussis Toxin; Pindolol; Propane; Rats; Receptors, Adrenergic; Sodium Fluoride; Virulence Factors, Bordetella | 1999 |
Impaired cholera toxin relaxation with age in rat aorta.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Aging; Animals; Aorta, Thoracic; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Isoproterenol; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred F344; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
P2 purinoceptors contribute to ATP-induced inhibition of L-type Ca2+ current in rabbit atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 5'-Nucleotidase; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enzyme Inhibitors; Isoproterenol; Myocardium; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Potassium Channels, Voltage-Gated; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Shal Potassium Channels; Suramin; Virulence Factors, Bordetella; Xanthines | 1999 |
Effects of noradrenaline, the calcium ionophore A23187, forskolin, sodium nitroprusside and glibenclamide on the degradation of extracellular adenosine 5'-triphosphate by the rat isolated vas deferens.
Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcimycin; Colforsin; Glyburide; Inosine; Male; Nitroprusside; Norepinephrine; Rats; Rats, Wistar; Time Factors; Vas Deferens | 1999 |
Potassium augments vascular relaxation mediated by nitric oxide in the carotid arteries of hypertensive Dahl rats.
Topics: Acetylcholine; Adenosine Diphosphate; Adrenergic beta-Agonists; Animals; Carotid Arteries; Colforsin; Dietary Supplements; Enzyme Inhibitors; Hypertension; Isoproterenol; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Nitroprusside; Penicillamine; Potassium, Dietary; Rats; Rats, Inbred Dahl; S-Nitroso-N-Acetylpenicillamine; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasodilation; Vasodilator Agents | 2000 |
Enhanced epinephrine-induced platelet aggregation in individuals carrying the G protein beta3 subunit 825T allele.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adenylate Cyclase Toxin; Adolescent; Adult; Alleles; Colforsin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Epinephrine; Heterotrimeric GTP-Binding Proteins; Humans; In Vitro Techniques; Isoenzymes; Male; Membrane Proteins; P-Selectin; Pertussis Toxin; Platelet Aggregation; Polymorphism, Genetic; Prostaglandin-Endoperoxide Synthases; Thrombin; Vasopressins; Virulence Factors, Bordetella | 2000 |
Parathyroid hormone potentiates nucleotide-induced [Ca2+]i release in rat osteoblasts independently of Gq activation or cyclic monophosphate accumulation. A mechanism for localizing systemic responses in bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Gene Expression; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Osteoblasts; Parathyroid Hormone; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 2001 |
Protein kinase A cascade regulates quantal release dispersion at frog muscle endplate.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; Motor Endplate; Muscle, Skeletal; Norepinephrine; Phosphodiesterase Inhibitors; Pressure; Rana ridibunda; Reaction Time; Synapses | 2002 |
Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Blood Platelet Disorders; Blood Platelets; Calcium; Carbon Radioisotopes; Cell Membrane; Colforsin; Collagen; Cyclic AMP; Diglycerides; DNA, Complementary; Epinephrine; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Male; Monocytes; Phosphorus Radioisotopes; Platelet Aggregation; Sequence Analysis, DNA; Serotonin; Signal Transduction; Thrombin; Thromboxane B2; Tritium | 2003 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
ATP release triggered by activation of the Ca2+-activated K+ channel in human airway Calu-3 cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Benzimidazoles; Bumetanide; Calcium; Cell Size; Charybdotoxin; Chlorzoxazone; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Cytosol; Epithelial Cells; Glyburide; Humans; Ionomycin; Isoproterenol; Luciferases; Lung; Potassium Channels, Calcium-Activated; Potassium Chloride; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2Y1 | 2004 |
Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Alanine; Amino Acid Substitution; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cysteine; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutation; Pertussis Toxin; Protein Binding; Protein Subunits; RGS Proteins; Thermodynamics; Trypsin; Tryptophan | 2004 |
Characterization of mechanisms involved in secretion of active heparanase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Line; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glucuronidase; HCT116 Cells; HT29 Cells; Humans; Lysosomes; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Purinergic receptor activation inhibits mitogen-stimulated proliferation in primary neurospheres from the adult mouse subventricular zone.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Colforsin; Cyclic AMP; Mice; Mice, Inbred CBA; Neurons; Nucleotides; Protein Isoforms; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Thionucleotides; Tissue Culture Techniques | 2007 |
Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.
Topics: Adenosine Diphosphate; Animals; Arginine; Binding, Competitive; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element Modulator; Humans; Isomerism; Luciferases; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sulfonic Acids; Suramin; Thionucleotides; Triazines | 2009 |
Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Blotting, Western; Colforsin; Cyclic GMP; Enzyme-Linked Immunosorbent Assay; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2011 |
The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Platelets; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Epoprostenol; Mice; Mice, Knockout; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Proto-Oncogene Proteins c-akt; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y; Signal Transduction; Thionucleosides | 2012 |
Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.
Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Binding, Competitive; CHO Cells; Colforsin; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Mutation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Response Elements; Thionucleotides; Ticagrelor; Transfection | 2014 |
Physiological characterization of the human EndoC-βH1 β-cell line.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Calcium Channels; Cell Line; Colforsin; Founder Effect; Gene Expression; Glucokinase; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glutamine; Glyburide; Humans; Insulin; Insulin-Secreting Cells; Keto Acids; Leucine; Mannoheptulose; Phosphorylation; Potassium Channels, Inwardly Rectifying | 2015 |
Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.
Topics: Adenosine; Adenosine Diphosphate; Blood Platelets; Calcium; Calcium Signaling; Cell Adhesion Molecules; Colforsin; Cyclic AMP; Equilibrative Nucleoside Transporter 1; Female; Humans; Male; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Receptors, Purinergic P2Y12; Ticagrelor | 2016 |
Participation of the adenosine salvage pathway and cyclic AMP modulation in oocyte energy metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Bucladesine; Coculture Techniques; Colforsin; Cumulus Cells; Cyclic AMP; Energy Metabolism; Female; Gap Junctions; Gene Expression; In Vitro Oocyte Maturation Techniques; Meiosis; Mice; Oocytes | 2019 |