Page last updated: 2024-08-23

colforsin and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

colforsin has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (15.38)18.2507
2000's29 (74.36)29.6817
2010's4 (10.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cowen, DS; Manning, DR; Sowers, RS1
Ballotti, R; Bertolotto, C; Buscà, R; Ortonne, JP1
Bockaert, J; Journot, L; Villalba, M1
Ai, W; Gong, J; Yu, L1
Edinger, RS; Johnson, JP; Rokaw, MD1
Cheng, HL; Delaney, CL; Feldman, EL1
Conner, TD; Dickson, JL; Ecay, TW1
Amemiya-Kudo, M; Gotoda, T; Harada, K; Hasty, AH; Iizuka, Y; Ishibashi, S; Nagai, R; Ohashi, K; Okazaki, H; Osuga, J; Perrey, S; Shimano, H; Shionoiri, F; Tamura, Y; Yahagi, N; Yamada, N; Yoshikawa, T1
Boushey, RP; Drucker, DJ; Yusta, B1
Grewal, SS; McCleskey, EW; Molliver, DC; Stenberg, PE; Stork, PJ; York, RD1
Kuemmerle, JF; Murthy, KS1
Arita, J; Kawashima, K; Yamakawa, K1
Chern, Y; Huang, CL; Huang, NK; Lin, YW; Messing, RO1
Byrnes, HD; Fine, JS; Hipkin, RW; Zavodny, PJ1
Combes, P; Crumiere, M; Dickenson, JM; Graham, S; Klotz, KN1
Chang, WC; Gean, PW; Leu, TH; Lin, CH; Lu, KT; Yeh, SH1
García, B; Santisteban, P1
Shimada, M; Terada, T1
Kang, SY; Kim, HM; Kim, NS; Park, SJ1
Mann, GE; Morgan, AJ; Pearson, JD; Sobrevia, L; Steinert, JR; Sugden, D; Wheeler-Jones, CP; Wyatt, AW1
Blomhoff, HK; Gutzkow, KB; Koketsu, M; Låhne, HU; Naderi, S; Skålhegg, B; Torgersen, KM; Uehara, Y1
Facci, L; Franceschini, D; Pangallo, M; Skaper, SD; Stevens, DA; Strijbos, PJ1
Ishikawa, K; Tokumoto, T; Watanabe, K1
Fuse, M; Kohn, LD; Misawa, N; Noguchi, Y; Saito, Y; Shibata, T; Tanaka, T; Tatsuno, I; Yasuda, T; Yoshida, T1
Campbell, JR; Husted, RF; Thomas, CP; Wright, PJ1
Gosmanov, AR; Thomason, DB; Thompson, DB1
Chakir, K; Crow, MT; Jo, SH; Lakatta, EG; Leblais, V; Maltsev, V; Wang, W; Xiao, RP; Zheng, M1
Bockaert, J; Bouschet, T; Fernandez, C; Journot, L; Perez, V1
Misra, UK; Pizzo, SV1
Bengtsson, T; Evans, BA; Nevzorova, J; Summers, RJ1
Hintze, TH; Zhang, XP1
Ibe, BO; Portugal, AM; Raj, JU1
Ji, X; Lipsius, SL; Pabbidi, M; Samarel, AM; Wang, YG1
Hanada, K; Iwasaki, Y; Kageyama, K; Nigawara, T; Sakihara, S; Suda, T; Takayasu, S1
Konstantopoulos, K; Wang, P; Zhu, F1
Bayat, AA; Ghorbani, A; Jeddi-Tehrani, M; Safa, M; Saidpour, A; Zand, H1
Kirkpatrick, CJ; Michel-Schmidt, R; Wessler, I1
Fehrenbacher, JC; Hudmon, A; Malty, RH; Vasko, MR1

Other Studies

39 other study(ies) available for colforsin and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Activation of a mitogen-activated protein kinase (ERK2) by the 5-hydroxytryptamine1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis.
    The Journal of biological chemistry, 1996, Sep-13, Volume: 271, Issue:37

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Androstadienes; Animals; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Norbornanes; Pertussis Toxin; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiocarbamates; Thiones; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin

1996
Inhibition of the phosphatidylinositol 3-kinase/p70(S6)-kinase pathway induces B16 melanoma cell differentiation.
    The Journal of biological chemistry, 1996, Dec-13, Volume: 271, Issue:50

    Topics: Animals; Cell Differentiation; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Melanoma, Experimental; Mice; Microscopy, Fluorescence; Monophenol Monooxygenase; Morpholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sirolimus

1996
Concomitant induction of apoptosis and necrosis in cerebellar granule cells following serum and potassium withdrawal.
    Neuroreport, 1997, Mar-03, Volume: 8, Issue:4

    Topics: Androstadienes; Animals; Apoptosis; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Chromones; Colforsin; Culture Media; Culture Media, Serum-Free; DNA; DNA Fragmentation; Enzyme Inhibitors; Insulin-Like Growth Factor I; Morpholines; Necrosis; Neurons; Neuropeptides; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Rats; Rats, Wistar; Wortmannin

1997
MAP kinase activation by mu opioid receptor involves phosphatidylinositol 3-kinase but not the cAMP/PKA pathway.
    FEBS letters, 1999, Jul-30, Volume: 456, Issue:1

    Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Chromones; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Maleimides; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Narcotics; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Opioid, mu; Recombinant Proteins; Thionucleotides; Transfection; Wortmannin

1999
Vasopressin stimulates sodium transport in A6 cells via a phosphatidylinositide 3-kinase-dependent pathway.
    The American journal of physiology, 1999, Volume: 277, Issue:4

    Topics: Androstadienes; Biological Transport; Cell Line; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Sodium; Vasopressins; Wortmannin

1999
Insulin-like growth factor-I prevents caspase-mediated apoptosis in Schwann cells.
    Journal of neurobiology, 1999, Volume: 41, Issue:4

    Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Chromones; Colforsin; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Insulin; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve

1999
Inhibition of phosphatidylinositol 3-kinase does not alter forskolin-stimulated Cl(-) secretion by T84 cells.
    American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:5

    Topics: Androstadienes; Cell Compartmentation; Cell Line; Cell Membrane; Chlorides; Chromones; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Ion Transport; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Thapsigargin; Wortmannin

2000
Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.
    The Journal of biological chemistry, 2000, Oct-06, Volume: 275, Issue:40

    Topics: Animals; Antimetabolites, Antineoplastic; Azaserine; Blotting, Northern; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Line; Cell Membrane; Cell Nucleus; Chromones; Colforsin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acid Synthases; Fructose; Fructosephosphates; Galactose; Genes, Reporter; Glucose; Immunoblotting; Liver; Mice; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Isoforms; Ribonucleases; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Temperature; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Up-Regulation; Xylose

2000
The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway.
    The Journal of biological chemistry, 2000, Nov-10, Volume: 275, Issue:45

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection

2000
Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.
    Molecular and cellular biology, 2000, Volume: 20, Issue:21

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Western; Cell Differentiation; Cell Survival; Cells, Cultured; Chromatography, Affinity; Chromones; Colforsin; Dose-Response Relationship, Drug; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Ganglia, Spinal; Immunohistochemistry; Luciferases; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; Morpholines; Nerve Growth Factor; PC12 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-raf; rap1 GTP-Binding Proteins; ras Proteins; Rats; Receptor, trkA; Signal Transduction; Time Factors; Transfection

2000
Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma -dependent mitogen-activated protein kinase activation and growth.
    The Journal of biological chemistry, 2001, Mar-09, Volume: 276, Issue:10

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Division; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Heterotrimeric GTP-Binding Proteins; Humans; Insulin-Like Growth Factor II; Intestinal Mucosa; MAP Kinase Signaling System; Morpholines; Muscle, Smooth; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, IGF Type 1; Recombinant Proteins; Time Factors; Virulence Factors, Bordetella

2001
Involvement of phosphoinositide-3-kinase and p70 S6 kinase in regulation of proliferation of rat lactotrophs in culture.
    Endocrine, 2000, Volume: 13, Issue:3

    Topics: Adenylyl Cyclases; Androstadienes; Animals; Bromocriptine; Bromodeoxyuridine; Bucladesine; Cell Division; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Homeostasis; Insulin; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Sirolimus; Wortmannin

2000
Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Cell Membrane; Cell Nucleus; Cell Survival; Chromones; Colforsin; Coloring Agents; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Dominant; MAP Kinase Signaling System; Models, Biological; Morpholines; PC12 Cells; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetrazolium Salts; Thiazoles; Time Factors; Transfection

2001
Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis.
    Inflammation, 2001, Volume: 25, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemotactic Factors; Chemotaxis, Leukocyte; Chromones; Colforsin; Flavonoids; Humans; In Vitro Techniques; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Signal Transduction; Wortmannin

2001
Regulation of p42/p44 mitogen-activated protein kinase by the human adenosine A3 receptor in transfected CHO cells.
    European journal of pharmacology, 2001, May-18, Volume: 420, Issue:1

    Topics: Adenosine; Androstadienes; Animals; CHO Cells; Chromones; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Luciferases; Mitogen-Activated Protein Kinase 1; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Receptor, Adenosine A3; Receptors, Purinergic P1; Recombinant Fusion Proteins; Wortmannin

2001
A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala.
    Neuron, 2001, Sep-13, Volume: 31, Issue:5

    Topics: Afferent Pathways; Amygdala; Androstadienes; Animals; Chromones; Colforsin; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dimethyl Sulfoxide; Electric Stimulation; Enzyme Inhibitors; Fear; Long-Term Potentiation; Male; MAP Kinase Signaling System; Memory; Morpholines; Neuronal Plasticity; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses; Wortmannin

2001
PI3K is involved in the IGF-I inhibition of TSH-induced sodium/iodide symporter gene expression.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:2

    Topics: Animals; Blotting, Western; Cell Line; Chromones; Colforsin; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Rats; RNA, Messenger; Signal Transduction; Symporters; Thyroid Gland; Thyrotropin; Transcriptional Activation; Transfection

2002
Roles of cAMP in regulation of both MAP kinase and p34(cdc2) kinase activity during meiotic progression, especially beyond the MI stage.
    Molecular reproduction and development, 2002, Volume: 62, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; CDC2 Protein Kinase; Cell Nucleus; Cells, Cultured; Chromatography, High Pressure Liquid; Chromones; Colforsin; Cyclic AMP; Female; Meiosis; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Oocytes; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Swine; Time Factors

2002
Phosphatidylinositol 3-kinase regulates PMA-induced differentiation and superoxide production in HL-60 cells.
    Immunopharmacology and immunotoxicology, 2002, Volume: 24, Issue:2

    Topics: Androstadienes; Apoptosis; Bucladesine; Cell Differentiation; Cell Division; Chromones; Colforsin; Enzyme Inhibitors; HL-60 Cells; Humans; Monocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases, 70-kDa; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin

2002
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:12

    Topics: Adenosine; Androstadienes; Arginine; Biological Transport; Butadienes; Calcium; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Gene Expression; Genistein; Humans; Hydrogen-Ion Concentration; MAP Kinase Signaling System; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitriles; Phenethylamines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Potassium; Protein Isoforms; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Wortmannin

2002
Cyclic AMP inhibits translation of cyclin D3 in T lymphocytes at the level of elongation by inducing eEF2-phosphorylation.
    Cellular signalling, 2003, Volume: 15, Issue:9

    Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D3; Cyclins; Cycloheximide; DNA Replication; Down-Regulation; Elongation Factor 2 Kinase; Flow Cytometry; G1 Phase; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Jurkat Cells; Morpholines; Organoselenium Compounds; Peptide Chain Elongation, Translational; Peptide Elongation Factor 2; Phosphorylation; Polyribosomes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; T-Lymphocytes; Transfection

2003
Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; Amphibian Proteins; Amyloid beta-Peptides; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Chromatin; Chromones; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glycogen Synthase Kinase 3; Hippocampus; In Situ Nick-End Labeling; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neurons; Neuroprotective Agents; Peptide Fragments; Peptide Hormones; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Thionucleotides; Time Factors; Urocortins; Urotensins; Vasodilator Agents

2003
1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate

2003
Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Alkyl and Aryl Transferases; Animals; Cattle; Cell Division; Cell Line; Chromones; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Enzyme Inhibitors; Geranylgeranyl-Diphosphate Geranylgeranyltransferase; Growth Substances; Humans; Hydroxymethylglutaryl CoA Reductases; Insulin; Mevalonic Acid; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; RNA, Messenger; Thyroid Gland; Thyrotropin

2004
cAMP-stimulated Na+ transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 287, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Cell Line; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Epithelial Sodium Channels; Humans; Immediate-Early Proteins; Kinetics; Lung; Morpholines; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Respiratory Mucosa; Sodium; Sodium Channels

2004
Regulation of Na(+)-K(+)-2Cl- cotransporter activity in rat skeletal muscle and intestinal epithelial cells.
    Tsitologiia, 2003, Volume: 45, Issue:8

    Topics: Animals; Bumetanide; Butadienes; Cell Line; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastrointestinal Tract; Indoles; Isoproterenol; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Skeletal; Nitriles; Potassium; Rats; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sulfonamides

2003
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
    Circulation research, 2004, Dec-10, Volume: 95, Issue:12

    Topics: Androstadienes; Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Chromones; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Insulin-Like Growth Factor I; Ion Transport; Isoproterenol; Morpholines; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Patch-Clamp Techniques; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prazosin; Propanolamines; Protein Processing, Post-Translational; Rats; Receptors, Adrenergic, beta-1; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Wortmannin

2004
Dynamic reorganization of the astrocyte actin cytoskeleton elicited by cAMP and PACAP: a role for phosphatidylInositol 3-kinase inhibition.
    The European journal of neuroscience, 2005, Volume: 21, Issue:1

    Topics: Actins; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cell Count; Cells, Cultured; Cerebellum; Chromones; Colforsin; Cyclic AMP; Drug Interactions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Immunohistochemistry; Indoles; Morpholines; Mutation; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Time Factors; Transfection

2005
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein

2005
Multiple signalling pathways involved in beta2-adrenoceptor-mediated glucose uptake in rat skeletal muscle cells.
    British journal of pharmacology, 2006, Volume: 147, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Bucladesine; Cell Line; Cholera Toxin; Chromones; Colforsin; Cyclic AMP; Dideoxyadenosine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanolamines; Glucose; Isoproterenol; Morpholines; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Rats; Receptors, Adrenergic, beta-2; Rolipram; Signal Transduction

2006
cAMP signal transduction induces eNOS activation by promoting PKB phosphorylation.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Chromones; Colforsin; Coronary Circulation; Coronary Vessels; Cyclic AMP; Dogs; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2006
Levalbuterol inhibits human airway smooth muscle cell proliferation: therapeutic implications in the management of asthma.
    International archives of allergy and immunology, 2006, Volume: 139, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Asthma; Bronchodilator Agents; Cell Line; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Isoproterenol; Morpholines; Muscle, Smooth; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipid Ethers; Platelet Aggregation Inhibitors; Propanolamines; Retinoblastoma Protein

2006
Laminin acts via focal adhesion kinase/phosphatidylinositol-3' kinase/protein kinase B to down-regulate beta1-adrenergic receptor signalling in cat atrial myocytes.
    The Journal of physiology, 2009, Feb-01, Volume: 587, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channels, L-Type; Cats; Chromones; Colforsin; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Humans; Isoproterenol; Laminin; Male; Morpholines; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propanolamines; Proto-Oncogene Proteins c-akt; Receptors, Adrenergic, beta; Signal Transduction

2009
Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:12

    Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection

2008
Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:6

    Topics: Adenylyl Cyclases; Androstadienes; Binding Sites; Cells, Cultured; Chondrocytes; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Enzyme Activators; Humans; Interleukin-6; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factor RelA; Transcriptional Activation; Up-Regulation; Wortmannin

2010
PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells.
    Archives of biochemistry and biophysics, 2015, Jan-15, Volume: 566

    Topics: Androstadienes; Antibodies; Apoptosis; Arrestins; B-Lymphocytes; beta-Arrestins; Cell Differentiation; Cell Line, Tumor; Chromones; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA Damage; DNA Repair; Gene Expression Regulation, Leukemic; Humans; Isoquinolines; Morpholines; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Suppressor Protein p53; Wortmannin

2015
Effect of LIF-withdrawal on acetylcholine synthesis in the embryonic stem cell line CGR8 is not mediated by STAT3, PI3Ks or cAMP/PKA pathways.
    International immunopharmacology, 2015, Volume: 29, Issue:1

    Topics: Acetylcholine; Animals; Chromones; Colforsin; Curcumin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Embryonic Stem Cells; Gene Expression Regulation, Enzymologic; Isoquinolines; Leukemia Inhibitory Factor; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Signal Transduction; STAT3 Transcription Factor; Sulfonamides

2015
Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.
    Journal of neuroinflammation, 2016, 07-11, Volume: 13, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Capsaicin; Cells, Cultured; Chromones; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Ganglia, Spinal; Isoquinolines; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Sensory Receptor Cells; Sensory System Agents; Signal Transduction; Sulfonamides; Time Factors

2016