Page last updated: 2024-08-22

coformycin and adenosine

coformycin has been researched along with adenosine in 125 studies

Research

Studies (125)

TimeframeStudies, this research(%)All Research%
pre-1990108 (86.40)18.7374
1990's9 (7.20)18.2507
2000's6 (4.80)29.6817
2010's2 (1.60)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antonini, I; Cristalli, G; Franchetti, P; Grifantini, M; Lupidi, G; Martelli, S; Riva, F1
Cheviet, T; Lefebvre-Tournier, I; Peyrottes, S; Wein, S1
Kiffe, H; Puchstein, C; Schwabe, U; Trost, T1
Muller, MJ; Paton, DM1
Arendes, J; Maidhof, A; Müller, WE; Umezawa, H; Zahn, RK1
Glazer, RI; Legraverend, M1
Glazer, RI; Peale, AL2
Johnson, RM; Lightbody, JJ; Uberti, J1
Lum, CT; Marz, R; Plagemann, PG; Wohlhueter, RM1
Cristalli, G; Falasca, M; Lupidi, G; Marmocchi, F; Riva, F; Venardi, G1
Cunha, RA; Sebastião, AM1
Bass, BL; Crain, PF; McCloskey, JA; Polson, AG; Pomerantz, SC1
Begleiter, A; Cavers, DJ; Israels, LG; Johnston, JB; Leith, MK; Pugh, L; Wilkins, JA1
Bakkeren, JA; De Abreu, RA; van Baal, JM; van der Kraan, PM; van Zandvoort, PM1
Columbo, M; Kagey-Sobotka, A; Lichtenstein, LM; Marone, G; Peachell, PT1
Lichtenstein, LM; Peachell, PT; Schleimer, RP1
Altschuld, RA; Brierley, GP; Hohl, CM; Wimsatt, DK1
Blanc, CM; Cataldo, F; Derossi, G; Ho, AD; Kuse, R; Lauria, F; McVie, G; Stryckmans, P; Thaler, J; Willemze, R1
Ogasawara, N; Roth, E; Schulman, S1
Baker, DC; Hebbler, AK; Pornbanlualap, S; Suhadolnik, RJ; Tiwari, KN1
Hostetter, MK; Johnson, GM1
Bontemps, F; Van den Berghe, G1
Marquardt, DL; Walker, LL1
Fraser, LR; Monks, NJ1
Allan, PW; Bennett, LL; Brockman, RW; Clayton, JD; Rose, LM; Shaddix, SC; Shealy, YF1
Belt, JA; Jarvis, SM; Paterson, AR; Wu, JS; Young, JD1
de Bruijn, CH; Dinjens, WN; Roos, D; van Doorn, R; van Laarhoven, JP; Zeijlemaker, WP1
Fabian, I; Williams, Z1
Hammerschmidt, DE; Skubitz, KM; Wickham, NW1
O'Regan, MH; Phillis, JW; Walter, GA1
Klenow, H; Ostergaard, E1
Burnstock, G; Centelles, JJ; Franco, R; Hoyle, CH1
Ballerini, P; Caciagli, F; Ciccarelli, R; Di Iorio, P; Tacconelli, L1
Decking, UK; Juengling, E; Kammermeier, H1
Das, DK; Steinberg, H1
Buc, HA; Garreau, F; Hamet, M; Moncion, A; Pérignon, JL; Thuillier, L1
Ingolia, DE; Kaufman, RJ; Kellems, RE; Murtha, P; Yeung, CY1
Holland, MJ1
Chen, SF; Cleaveland, JS; Hollmann, AB; Parks, RE; Stoeckler, JD; Wiemann, MC1
Plagemann, PG1
Boston, G; Paton, DM; Webster, DR1
Bakkeren, JA; De Abreu, RA; de Bruijn, CH; van der Krann, PM; van Laarhoven, JP; van Zandvoort, PM1
Carson, DA; Kajander, EO; Kubota, M; Willis, EH1
Bontemps, F; Hers, HG; Van den Berghe, G1
Heike, T; Katamura, K; Kubota, M; Mikawa, H; Shinomiya, K1
DeLong, RE; Phillis, JW1
Kontinen, VP; Pispa, JP1
Baker, DC; Dechter, JJ; Hanvey, JC; Hawkins, ES; Suhadolnik, RJ; Tunac, JB1
Dmitrenko, NP; Goroshnikova, TV1
Kraupp, M; Plagemann, PG; Wohlhueter, RM2
Hubbell, HR; Lee, C; Pequignot, EC; Suhadolnik, RJ; Willis, DH1
Plagemann, PG; Wohlhueter, RM3
Cohen, MB; Glazer, RI1
Wolberg, G; Zimmerman, TP1
Archer, S; Chan, VL; Ho, JH; Juranka, PF1
Frayne, EG; Harrison, ML; Ingolia, DE; Kellems, RE; Orengo, IF; Rudolph, FB; Yeung, CY1
Akuzawa, Y; Kurashige, S; Mitsuhashi, S1
Saito, T; Yamaguchi, J1
Bugg, CE; Einsphar, HM; Montgomery, JA; Thomas, HJ; Zell, AL1
Calabresi, P; Crabtree, GW; Cummings, FJ; Jordan, M; LaBresh, K; Spremulli, EN1
Buttin, G; Debatisse, M; Fernandez-Mejia, C1
Azuma, H; Ishikawa, M; Takashima, Y; Yamakado, T1
Conti, M; Monaco, L; Toscano, MV1
Bagnara, AS; Kyd, JM1
Creveling, CR; Daly, JW; McNeal, ET1
Daly, JW; Nimit, Y; Skolnick, P1
Agarwal, RP; Kufe, DW; Major, PP3
Holmquist, CA; Newby, AC1
Behrman, HR; Brennan, TJ; Gore, SD; Ohkawa, R1
Chagoya de Sanchez, V; Souness, JE; Stouffer, JE1
Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G1
Glazer, RI; Knode, MC1
Daddona, PE; Kelley, WN; Lambros, C; Webster, HK; Wiesmann, WP1
Barankiewicz, J; Cohen, A1
Hudig, D; Redelman, D1
Carson, DA; Iizasa, T; Kubota, M1
Cseppentö, A; Németh, M; Papp, JG; Szegi, J; Szekeres, L; Szentmiklósi, AJ2
Bergeron, M; Hoang, T1
Falletta, JM; Hershfield, MS; Kinney, TR; Koller, CA; Kredich, NM; Kurtzberg, J; Mitchell, BS1
Helland, S; Ueland, PM1
Holmquist, CA; Illingworth, J; Newby, AC; Pearson, JD1
Chang, Y; Hacker, B2
Broch, OJ; Helland, S; Ueland, PM1
Djuricic-Nedelson, M; Green, RD; Radulovacki, M; Virus, RM1
Baker, DC; Hanvey, JC; Hardman, JK; Suhadolnik, RJ1
Ametani, MS; Belzer, FO; Lutz, MF; Southard, JH1
Baer, HP; Vriend, R1
Heyn, R; Koller, CA; Mitchell, BS1
Balis, ME; Good, RA; Ikehara, S; Pahwa, R; Tedde, A; Trotta, PP1
Hayward, AR1
Coleman, MS; Hutton, JJ; Koller, CA; Mitchell, BS; Siaw, MF1
Koller, CA; Mitchell, BS; Nichamin, LD; Stetson, PL1
Cybulski, RL; Fry, DW; Goldman, ID1
Blatt, J; Glazer, RI; Holcenberg, JS; Lipton, J; Murphy, SB; Poplack, DG; Rivera, G; Sallan, S; Venner, PM1
Cartier, PH; Garreau, F; Thuillier, L1
Cass, CE; Muhs, WH; Robins, MJ; Selner, M; Tan, TH1
Hirschhorn, R; Kuritsky, L; Ratech, H; Thorbecke, GJ1
Kuttesch, JF; Nelson, JA1
Calabresi, P; Chu, SH; Crabtree, GW; Dexter, DL; Diamond, I; Farineau, DM; Ghoda, LY; McGowan, DL; Parks, RE; Spremulli, EN1
Helmsworth, M; Ritch, PS1
Belch, A; Brox, LW; Pollock, E1
Kotb, M; Veit, BC1
Braun, J; Rosen, FS; Unanue, ER1
Hirschhorn, R; Kuritsky, L; Roegner-Maniscalco, V; Rosen, FS1
Kamiya, T; Tanaka, Y; Tsuyuki, M; Yoshihara, K1
Blay, J; Hoskin, DW; White, TD1
Britt, BM; Castro, C1
Dale, N1
Browning, MJ; Hohl, CM; Jurkowitz, MS; Litsky, ML1
Dancer, JE; Dudfield, PJ; Earnshaw, CG; Hewitt, BD; Lindell, SD; Moloney, BA1
Barry, CP; Lind, SE1
Dale, N; Frenguelli, BG; Pearson, T1
Fujimori, H; Pan-Hou, H; Yasuda, M1
Knowles, AF; Wen, LT1
Eguchi, N; Hayaishi, O; Huang, ZL; Mochizuki, T; Okada, T; Sugita, Y; Urade, Y1
Fredholm, BB; Hayaishi, O; Huang, ZL; Oishi, Y; Urade, Y1
Cai, YS; Chen, W; Deng, Z; Gao, Y; Gong, R; Hong, K; Hu, Y; Jiang, M; Kong, L; Liu, P; Price, NPJ; Xu, G; Xu, L1

Reviews

1 review(s) available for coformycin and adenosine

ArticleYear
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
    Journal of medicinal chemistry, 2019, 09-26, Volume: 62, Issue:18

    Topics: Antimalarials; Biological Transport; Drug Design; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria; Nucleosides; Nucleotides; Plasmodium falciparum; Purines; Pyrimidines

2019

Trials

1 trial(s) available for coformycin and adenosine

ArticleYear
Pentostatin (2'deoxycoformycin) for the treatment of lymphoid neoplasms.
    Bone marrow transplantation, 1989, Volume: 4 Suppl 1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Antineoplastic Agents; Coformycin; DNA, Neoplasm; Drug Evaluation; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Multicenter Studies as Topic; Neoplasm Proteins; Pentostatin; Ribonucleosides; Sezary Syndrome

1989

Other Studies

123 other study(ies) available for coformycin and adenosine

ArticleYear
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Intestines; Nucleoside Deaminases

1984
Specific binding of 3H-adenosine to rat brain membranes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 310, Issue:1

    Topics: Adenosine; Animals; Binding Sites; Brain; Coformycin; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Membranes; Protein Binding; Rats; Temperature

1979
Presynaptic inhibitory actions of 2-substituted adenosine derivatives on neurotransmission in rat vas deferens: effects of inhibitors of adenosine uptake and deamination.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 306, Issue:1

    Topics: Adenosine; Animals; Atropine; Coformycin; Deamination; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phenoxybenzamine; Rats; Synaptic Transmission; Theophylline; Vas Deferens

1979
Influence of coformycin on the cytostatic activity of 9-beta-D-arabinofuranosyladenine and adenosine in mouse L5178y cells.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1978, Volume: 359, Issue:10

    Topics: Adenosine; Cell Division; Cell Line; Coformycin; Deoxyadenosines; Kinetics; Ribonucleosides; Vidarabine

1978
Inhibition of the phosphorylation of nonhistone chromosomal proteins by cordycepin and xylosyladenine in L1210 cells in vitro.
    Molecular pharmacology, 1978, Volume: 14, Issue:6

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Chromosomal Proteins, Non-Histone; Coformycin; Deoxyadenosines; In Vitro Techniques; Isoelectric Focusing; Leukemia L1210; Mice; Neoplasm Proteins; Phosphorylation; RNA, Neoplasm; Xylose

1978
Evidence that xylosyladenine affects methylation by inhibition of S-adenosyl-L-methionine synthesis.
    Cancer letters, 1979, Volume: 6, Issue:4-5

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Nucleus; Coformycin; Deoxyadenosines; In Vitro Techniques; Leukemia L1210; Methylation; Mice; RNA, Neoplasm; S-Adenosylmethionine; Xylose

1979
The effect of nucleosides and deoxycoformycin on adenosine and deoxyadenosine inhibition of human lymphocyte activation.
    Journal of immunology (Baltimore, Md. : 1950), 1979, Volume: 123, Issue:1

    Topics: Adenosine; Cells, Cultured; Coformycin; Deoxyadenosines; Humans; Leucine; Lymphocyte Activation; Nucleosides; Ribonucleosides; Thymidine; Time Factors

1979
Adenosine transport and metabolism in mouse leukemia cells and in canine thymocytes and peripheral blood leukocytes.
    Journal of cellular physiology, 1979, Volume: 101, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Coformycin; Concanavalin A; Dipyridamole; Dogs; Hypoxanthines; Kinetics; Leukemia P388; Leukemia, Experimental; Leukocytes; Mice; T-Lymphocytes

1979
Potentiation by 2'-deoxycoformycin of the inhibitory effect of xylosyladenine on nuclear RNA synthesis in L1210 cells in vitro.
    Biochemical pharmacology, 1978, Volume: 27, Issue:21

    Topics: Adenosine; Adenosine Deaminase; Animals; Cell Nucleus; Coformycin; Leukemia L1210; Mice; Ribonucleosides; RNA, Neoplasm; Time Factors; Xylose

1978
Adenosine deaminase from bovine brain: purification and partial characterization.
    Biochemistry international, 1992, Volume: 26, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; Cattle; Coformycin; Cytoplasm; Enzyme Stability; In Vitro Techniques; Isoelectric Point; Kinetics; Molecular Weight; Pentostatin; Temperature

1992
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine

1991
The mechanism of adenosine to inosine conversion by the double-stranded RNA unwinding/modifying activity: a high-performance liquid chromatography-mass spectrometry analysis.
    Biochemistry, 1991, Dec-10, Volume: 30, Issue:49

    Topics: Adenosine; Coformycin; Deamination; Gas Chromatography-Mass Spectrometry; Hydrolysis; Inosine; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oxygen; RNA, Double-Stranded; Water

1991
Biochemical changes induced in hairy-cell leukemia following treatment with the adenosine deaminase inhibitor 2'-deoxycoformycin.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Aged; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Humans; Interferons; Leukemia, Hairy Cell; Leukocyte Count; Male; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1986
Inhibition of lymphoid cell growth by adenine ribonucleotide accumulation. The role of phosphoribosylpyrophosphate-depletion induced pyrimidine starvation.
    Biochimica et biophysica acta, 1987, Feb-18, Volume: 927, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Cycle; Cell Division; Cell Line; Coformycin; Humans; Hypoxanthine Phosphoribosyltransferase; Nucleoside Deaminases; Pentosephosphates; Pentostatin; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Ribonucleosides; Ribonucleotides; T-Lymphocytes

1987
Adenosine potentiates mediator release from human lung mast cells.
    The American review of respiratory disease, 1988, Volume: 138, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Coformycin; Dipyridamole; Drug Synergism; Histamine Release; Humans; Lung; Mast Cells; Nucleosides; Pentostatin; Receptors, Purinergic; SRS-A; Time Factors; Xanthines

1988
Inhibition by adenosine of histamine and leukotriene release from human basophils.
    Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11

    Topics: 2-Chloroadenosine; Adenosine; Basophils; Coformycin; Histamine Release; Humans; In Vitro Techniques; Pentostatin; SRS-A; Structure-Activity Relationship; Theophylline

1989
IMP production by ATP-depleted adult rat heart cells. Effects of glycolysis and alpha 1-adrenergic stimulation.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; AMP Deaminase; Animals; Cells, Cultured; Coformycin; Glycolysis; Heart; Inosine; Inosine Monophosphate; Inosine Nucleotides; Kinetics; Myocardium; NAD; Phenylephrine; Rats; Receptors, Adrenergic, beta; Ribonucleosides

1989
The deamination of adenosine and adenosine monophosphate in Plasmodium falciparum-infected human erythrocytes: in vitro use of 2'deoxycoformycin and AMP deaminase-deficient red cells.
    Blood, 1989, Aug-15, Volume: 74, Issue:3

    Topics: Adenosine; Adenosine Monophosphate; Adult; AMP Deaminase; Animals; Coformycin; Deamination; Erythrocytes; Female; Humans; Malaria; Nucleotide Deaminases; Pentostatin; Plasmodium falciparum; Ribonucleosides

1989
Stereospecific 2'-amination and 2'-chlorination of adenosine by Actinomadura in the biosynthesis of 2'-amino-2'-deoxyadenosine and 2'-chloro-2'-deoxycoformycin.
    Archives of biochemistry and biophysics, 1989, Volume: 270, Issue:1

    Topics: Actinomycetales; Adenosine; Amination; Anti-Bacterial Agents; Chlorine; Coformycin; Deoxyadenosines; Nucleosides; Pentostatin; Prodrugs; Stereoisomerism

1989
The erythrocyte as instigator of inflammation. Generation of amidated C3 by erythrocyte adenosine deaminase.
    The Journal of clinical investigation, 1989, Volume: 84, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Adult; Ammonia; Coformycin; Complement C3; Erythrocytes; Female; Humans; Inflammation; Male; Nucleoside Deaminases; Pentostatin

1989
Mechanism of adenosine triphosphate catabolism induced by deoxyadenosine and by nucleoside analogues in adenosine deaminase-inhibited human erythrocytes.
    Cancer research, 1989, Sep-15, Volume: 49, Issue:18

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Coformycin; Deoxyadenosines; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Structure-Activity Relationship

1989
Inhibition of mast cell adenosine responsiveness by chronic exposure to adenosine receptor agonists.
    Biochemical pharmacology, 1987, Dec-15, Volume: 36, Issue:24

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; beta-N-Acetylhexosaminidases; Calcimycin; Cells, Cultured; Coformycin; Cyclic AMP; Dose-Response Relationship, Drug; Isoproterenol; Mast Cells; Mice; Pentostatin; Receptors, Purinergic; SRS-A; Time Factors

1987
Inhibition of adenosine-metabolizing enzymes modulates mouse sperm fertilizing ability: a changing role for endogenously generated adenosine during capacitation.
    Gamete research, 1988, Volume: 21, Issue:3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Coformycin; Fertilization; Fertilization in Vitro; Male; Mice; Nucleotidases; Sperm Capacitation

1988
Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase.
    Molecular pharmacology, 1985, Volume: 27, Issue:6

    Topics: Adenosine; Animals; Carcinoma, Squamous Cell; Cell Line; Coformycin; Colonic Neoplasms; Cyclic GMP; Cyclic IMP; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Nucleotides; Kinetics; Leukemia L1210; Mice; Pentosyltransferases; Ribonucleotides

1985
Photoaffinity labeling of the human erythrocyte glucose transporter with 8-azidoadenosine.
    The Journal of biological chemistry, 1986, Aug-25, Volume: 261, Issue:24

    Topics: Adenosine; Affinity Labels; Azides; Blood Proteins; Coformycin; Cytochalasin B; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Membrane Proteins; Molecular Weight; Monosaccharide Transport Proteins; Nucleoside Transport Proteins; Pentostatin; Phenylisopropyladenosine; Phloretin; Photochemistry; Receptors, Cell Surface; Receptors, Purinergic; Thioinosine; Uridine

1986
Adenosine receptors on human T lymphocytes and human thymocytes.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adult; Child, Preschool; Coformycin; Cyclic AMP; Humans; In Vitro Techniques; Receptors, Purinergic; T-Lymphocytes; Thymus Gland

1986
The effect of deoxycoformycin on bone marrow cells treated with adenosine and deoxyadenosine and hemopoietic growth factors.
    Human immunology, 1988, Volume: 21, Issue:2

    Topics: Adenosine; Bone Marrow; Cell Division; Cells, Cultured; Coformycin; Deoxyadenosines; Growth Substances; Hematopoiesis; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; In Vitro Techniques; Pentostatin; Ribonucleosides; T-Lymphocytes

1988
Endogenous and exogenous adenosine inhibit granulocyte aggregation without altering the associated rise in intracellular calcium concentration.
    Blood, 1988, Volume: 72, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Body Fluids; Calcium; Cell Aggregation; Coformycin; Complement Activation; Granulocytes; Humans; Intracellular Fluid; N-Formylmethionine Leucyl-Phenylalanine; Pentostatin; Zymosan

1988
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1988, Volume: 8, Issue:5

    Topics: Adenosine; Animals; Cerebral Cortex; Coformycin; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides; Uric Acid; Xanthine; Xanthines

1988
Adenosine induction of rapid catabolism of adenine ribonucleotides and independent elevation of the ATP content in quiescent mouse fibroblasts.
    Journal of cellular physiology, 1988, Volume: 137, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Line; Coformycin; Deoxyadenosines; Guanosine Triphosphate; Inosine Monophosphate; Interphase; Kinetics; Mice

1988
Degradation of adenosine by extracellular adenosine deaminase in the rat duodenum.
    General pharmacology, 1988, Volume: 19, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Dilazep; Duodenum; In Vitro Techniques; Male; Muscle Contraction; Nucleoside Deaminases; Pentostatin; Rats; Rats, Inbred Strains

1988
Cultures of glial cells release purines under field electrical stimulation: the possible ionic mechanisms.
    Pharmacological research communications, 1988, Volume: 20, Issue:11

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain; Cells, Cultured; Coformycin; Electric Stimulation; Neuroglia; Nucleotides; Pentostatin; Pharmacology; Rats; Reference Values; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil

1988
Interstitial transudate concentration of adenosine and inosine in rat and guinea pig hearts.
    The American journal of physiology, 1988, Volume: 254, Issue:6 Pt 2

    Topics: Adenosine; Animals; Coformycin; Coronary Circulation; Dipyridamole; Exudates and Transudates; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Inosine; Myocardium; Oxygen Consumption; Perfusion; Rats

1988
Adenosine transport by the lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Azaguanine; Biological Transport, Active; Coformycin; Colchicine; Dipyridamole; Glucose; Kinetics; Lung; Male; Ouabain; Rats; Rats, Inbred Strains

1988
Energy metabolism in adenosine deaminase-inhibited human erythrocytes.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Apr-15, Volume: 156, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Energy Metabolism; Erythrocytes; Glycolysis; Humans; Hypoxanthine; Hypoxanthines; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1986
Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:10

    Topics: Adenosine; Adenosine Deaminase; Animals; Cloning, Molecular; Coformycin; Cricetinae; Drug Resistance; Gene Amplification; Gene Expression Regulation; Genetic Vectors; Mice; Nucleoside Deaminases; Pentostatin; RNA, Messenger

1986
Specificity of 2'-deoxycoformycin inhibition of adenosine metabolism in intact human skin fibroblasts.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Cells, Cultured; Coformycin; Dose-Response Relationship, Drug; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; Skin

1986
Changes in nucleoside transport of HL-60 human promyelocytic cells during N,N-dimethylformamide induced differentiation.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Cell Differentiation; Cell Line; Coformycin; Deoxyadenosines; Dimethylformamide; Humans; Leukemia, Myeloid, Acute; Nucleosides; Pentostatin; Purines; Thioinosine

1986
Transport and metabolism of adenosine in human erythrocytes: effect of transport inhibitors and regulation by phosphate.
    Journal of cellular physiology, 1986, Volume: 128, Issue:3

    Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Biological Transport; Coformycin; Dilazep; Dipyridamole; Erythrocytes; Humans; Pentostatin; Phosphates; Phosphorylation; Thioinosine

1986
Purine metabolism by guinea-pig ileum.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Coformycin; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NAD; Pentostatin; Purines; Receptors, Purinergic

1986
Inhibition of 3H-thymidine incorporation by adenosine and deoxyadenosine in human peripheral lymphocytes and malignant lymphoid cell lines.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Cell Line; Cells, Cultured; Coformycin; Deoxyadenosines; DNA; Humans; Lymphocyte Activation; Lymphocytes; Mitogens; Pentostatin; Thymidine

1986
S-adenosylmethionine metabolism as a target for adenosine toxicity.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenosine; Adenosine Kinase; Animals; Cell Line; Coformycin; Drug Resistance; Lymphoma; Methionine Adenosyltransferase; Mice; Pentostatin; S-Adenosylhomocysteine; S-Adenosylmethionine

1986
Pathways of adenine nucleotide catabolism in human erythrocytes.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Glucose; Coformycin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Pentostatin; Phosphates; Tubercidin

1986
Inhibitor of 2', 5'-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 2',5'-Oligoadenylate Synthetase; Adenosine; Cell Line; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Enzyme Induction; Homocysteine; Humans; Interferon Type I; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine

1986
An involvement of adenosine in cerebral blood flow regulation during hypercapnia.
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Adenosine; Animals; Blood Pressure; Caffeine; Cerebrovascular Circulation; Coformycin; Dipyridamole; Hypercapnia; Male; Pentostatin; Rats; Rats, Inbred Strains

1987
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
    Molecular and cellular biochemistry, 1987, Volume: 76, Issue:1

    Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine

1987
Biosynthesis of 2'-deoxycoformycin: evidence for ring expansion of the adenine moiety of adenosine to a tetrahydroimidazo[4,5-d][1,3]diazepine system.
    Biochemistry, 1987, Sep-08, Volume: 26, Issue:18

    Topics: Adenosine; Antineoplastic Agents; Carbon Radioisotopes; Coformycin; Indicators and Reagents; Inosine; Magnetic Resonance Spectroscopy; Pentostatin; Ribonucleosides

1987
[Characteristics of adenosine activity on adenine nucleotide metabolism of rat thymocytes].
    Biokhimiia (Moscow, Russia), 1985, Volume: 50, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport; Coformycin; Inosine; Inosine Monophosphate; Pentostatin; Rats; Rats, Inbred Strains; Thymus Gland

1985
Adenine nucleotide metabolism and nucleoside transport in human erythrocytes under ATP depletion conditions.
    Biochimica et biophysica acta, 1985, Jul-11, Volume: 817, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Biological Transport; Coformycin; Erythrocytes; Humans; Iodoacetamide; Iodoacetates; Iodoacetic Acid; Kinetics; Pentostatin; Tritium

1985
Differential antiproliferative actions of 2',5' oligo A trimer core and its cordycepin analogue on human tumor cells.
    International journal of cancer, 1985, Sep-15, Volume: 36, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Cell Division; Cell Line; Coformycin; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Humans; Neoplasms; Oligodeoxyribonucleotides; Oligonucleotides; Oligoribonucleotides; Pentostatin

1985
Adenosine uptake, transport, and metabolism in human erythrocytes.
    Journal of cellular physiology, 1985, Volume: 125, Issue:2

    Topics: Adenosine; Adenosine Kinase; Biological Transport; Cell Membrane; Coformycin; Erythrocytes; Humans; Intracellular Fluid; Kinetics; Pentostatin; Phosphorylation; Time Factors

1985
Effects of nucleoside transport inhibitors on the salvage and toxicity of adenosine and deoxyadenosine in L1210 and P388 mouse leukemia cells.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Adenosine; Animals; Biological Transport; Coformycin; Deoxyadenosines; Dipyridamole; Inosine; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Pentostatin; Thioinosine

1985
Inhibition of interleukin-2 messenger RNA in mouse lymphocytes by 2'-deoxycoformycin and adenosine metabolites.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenosine; Animals; Coformycin; Female; Immunosuppressive Agents; Interleukin-2; Kinetics; Lymphocytes; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Pentostatin; Ribonucleosides; RNA, Messenger; Spleen

1985
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic

1985
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
    Journal of cellular physiology, 1985, Volume: 124, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine

1985
Purification and characterization of adenosine deaminase from a genetically enriched mouse cell line.
    The Journal of biological chemistry, 1985, Oct-25, Volume: 260, Issue:24

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Electrophoresis, Polyacrylamide Gel; Gene Amplification; Half-Life; Immunosorbent Techniques; Isoelectric Focusing; Kinetics; Mice; Molecular Weight; Mutation; Nucleoside Deaminases; Pentostatin

1985
Purine metabolic enzymes in lymphocytes. IV. Effects of enzyme inhibitors and enzyme substrates on the blastogenic responses of human lymphocytes.
    Scandinavian journal of immunology, 1985, Volume: 22, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Allopurinol; Coformycin; Enzyme Inhibitors; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lymphocyte Activation; Lymphocytes; Mitogens; Purine-Nucleoside Phosphorylase; Purines; Xanthine Oxidase

1985
2-Chloroadenosine: a selective lethal effect to mouse macrophages and its mechanism.
    Journal of immunology (Baltimore, Md. : 1950), 1985, Volume: 134, Issue:3

    Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Ascitic Fluid; Cell Line; Cell Membrane; Cell Survival; Coformycin; Female; Iodoacetates; Iodoacetic Acid; Kinetics; Macrophages; Methylation; Mice; Purine Nucleosides

1985
Study on the inhibition of adenosine deaminase.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:11

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cattle; Chemical Phenomena; Chemistry; Coformycin; Nucleoside Deaminases; Ribonucleosides; Structure-Activity Relationship; X-Ray Diffraction

1985
Hemodynamic effects of potentially useful antineoplastic agents.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:3

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Coformycin; Dose-Response Relationship, Drug; Electrocardiography; Female; Formycins; Hemodynamics; Hypotension; Pentostatin; Rats; Rats, Inbred Strains; Vidarabine Phosphate

1983
Adenosine-resistant Chinese hamster fibroblast variants with hyperactive adenosine-deaminase: an analysis of the protection against exogenous adenosine afforded by increased activity of the deamination pathway.
    Journal of cellular physiology, 1984, Volume: 120, Issue:3

    Topics: Adenosine; Adenosine Deaminase; Animals; Cell Line; Coformycin; Cricetinae; Cricetulus; Drug Resistance; Fibroblasts; Hypoxanthine; Hypoxanthines; Inosine; Models, Chemical; Nucleoside Deaminases; Phosphoribosyl Pyrophosphate; Purines

1984
Potentiation of antiaggregating activity of adenosine by a phosphodiesterase inhibitor, EG626 (oxagrelate), in human platelets in vitro.
    Japanese journal of pharmacology, 1984, Volume: 34, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase Inhibitors; Adenylyl Cyclases; Coformycin; Collagen; Cyclic AMP; Drug Synergism; Humans; In Vitro Techniques; Male; Pentostatin; Phosphodiesterase Inhibitors; Phthalazines; Platelet Aggregation; Pyridazines

1984
Purine modulation of the hormonal response of the rat Sertoli cell in culture.
    Endocrinology, 1984, Volume: 115, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Binding, Competitive; Bucladesine; Cells, Cultured; Coformycin; Cyclic AMP; Follicle Stimulating Hormone; Isoproterenol; Male; Pentostatin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sertoli Cells

1984
Adenosine kinase from human erythrocytes: determination of the conditions required for assay in crude hemolystates.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Apr-25, Volume: 103, Issue:2

    Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Adult; Cations, Divalent; Chromatography, Thin Layer; Coformycin; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methods; Phosphotransferases; Reference Values

1980
Cyclic AMP-generating systems in cell-free preparations from guinea pig cerebral cortex: loss of adenosine and amine responsiveness due to low levels of endogenous adenosine.
    Journal of neurochemistry, 1980, Volume: 35, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Amines; Animals; Cell-Free System; Cerebral Cortex; Coformycin; Cyclic AMP; Guinea Pigs; Histamine; Male; Norepinephrine; Pentostatin

1980
Adenosine and cyclic AMP in rat cerebral cortical slices: effects of adenosine uptake inhibitors and adenosine deaminase inhibitors.
    Journal of neurochemistry, 1981, Volume: 36, Issue:3

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Brain; Catecholamines; Coformycin; Cyclic AMP; Dipyridamole; In Vitro Techniques; Male; Nucleoside Deaminases; Pentostatin; Rats; Veratridine

1981
Clinical pharmacology of deoxycoformycin.
    Blood, 1981, Volume: 58, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adolescent; Adult; Aged; Bronchitis; Coformycin; Coma; Conjunctivitis; Deoxyadenosines; Female; Humans; Kidney Diseases; Leukemia, Lymphoid; Lymphoma; Male; Middle Aged; Mycosis Fungoides; Nucleoside Deaminases; Pentostatin; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides

1981
Adenosine production inside rat polymorphonuclear leucocytes.
    The Biochemical journal, 1981, Nov-15, Volume: 200, Issue:2

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Coformycin; Neutrophils; Nucleotidases; Pentostatin; Rats; Tubercidin

1981
Adenine-derived purines increase adenosine triphosphate (ATP) levels in the luteal cell: evidence that cell levels of ATP may limit the stimulation of adenosine 3',5'-monophosphate accumulation by luteinizing hormone.
    Endocrinology, 1983, Volume: 112, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Coformycin; Corpus Luteum; Cyclic AMP; Dinoprost; Dose-Response Relationship, Drug; Female; Luteinizing Hormone; Prostaglandins F; Purine Nucleosides; Rats

1983
Effect of N6-methyladenosine on fat-cell glucose metabolism. Evidence for two modes of action.
    Biochemical pharmacology, 1982, Dec-15, Volume: 31, Issue:24

    Topics: Adenosine; Adipose Tissue; Animals; Coformycin; Cyclic AMP; Fatty Acids; Glucose; Glycerol; In Vitro Techniques; Male; Nucleosides; Oxidation-Reduction; Pentostatin; Rats; Rats, Inbred Strains; Theophylline

1982
Adenosine metabolism in wild-type and enzyme-deficient variants of Chinese hamster ovary and Novikoff rat hepatoma cells.
    Journal of cellular physiology, 1983, Volume: 116, Issue:2

    Topics: 2-Aminopurine; Adenine Nucleotides; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cell-Free System; Coformycin; Cricetinae; Female; Kinetics; Liver Neoplasms, Experimental; Ovary; Pentostatin; Phosphorylation; Phosphotransferases; Purine-Nucleoside Phosphorylase; Rats; Tubercidin

1983
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
    The Journal of experimental medicine, 1983, Oct-01, Volume: 158, Issue:4

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides

1983
Neplanocin A. A cyclopentenyl analog of adenosine with specificity for inhibiting RNA methylation.
    The Journal of biological chemistry, 1984, Nov-10, Volume: 259, Issue:21

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Antibiotics, Antineoplastic; Cell Line; Cell Survival; Coformycin; Colonic Neoplasms; DNA Replication; Humans; Kinetics; Methylation; Pentostatin; Protein Biosynthesis; Ribonucleosides; RNA, Ribosomal; Transcription, Genetic

1984
Adenosine deaminase in malaria infected erythrocytes: unique parasite enzyme presents a new therapeutic target.
    Progress in clinical and biological research, 1984, Volume: 165

    Topics: Adenosine; Adenosine Deaminase; Animals; Coformycin; Erythrocytes; Humans; Macaca mulatta; Malaria; Male; Nucleoside Deaminases; Pentostatin; Plasmodium

1984
Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.
    The Journal of biological chemistry, 1984, Dec-25, Volume: 259, Issue:24

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Coformycin; Deoxyadenine Nucleotides; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Kinetics; Pentostatin; Structure-Activity Relationship; T-Lymphocytes

1984
The mechanism of cell-mediated cytotoxicity. III. Protease-specific inhibitors preferentially block later events in cytotoxic T lymphocyte-mediated lysis than do inhibitors of methylation or thiol-reactive agents.
    Cellular immunology, 1983, Oct-01, Volume: 81, Issue:1

    Topics: Adenosine; alpha 1-Antichymotrypsin; Animals; Bridged Bicyclo Compounds; Calcium; Chymotrypsin; Coformycin; Cytotoxicity, Immunologic; Deoxyadenosines; Methylation; Mice; Mice, Inbred Strains; Pentostatin; Peptide Hydrolases; Sulfhydryl Compounds; T-Lymphocytes, Cytotoxic; Time Factors; Tyrosine

1983
Differential production of deoxyadenosine by human T and B lymphoblasts.
    Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 131, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Coformycin; Deoxyadenosines; Humans; Interphase; Lymphocyte Activation; Lymphoma, Large B-Cell, Diffuse; Pentostatin; T-Lymphocytes

1983
Effects of hypoxia on the guinea-pig myocardium following inhibition of adenosine deaminase by coformycin.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:2

    Topics: Action Potentials; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Female; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Myocardium; Nucleoside Deaminases; Oxygen; Ribonucleosides; Time Factors

1984
Adenosine and compensatory renal growth.
    Kidney international, 1983, Volume: 23, Issue:4

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Division; Coformycin; Hypertrophy; Kidney; Male; Nephrectomy; Rats; Rats, Inbred Strains

1983
Clinical pharmacology of arabinofuranosyladenine in combination with deoxycoformycin.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:2

    Topics: Adenosine; Adult; Antineoplastic Agents; Coformycin; Deoxyadenosines; Drug Administration Schedule; Drug Therapy, Combination; Half-Life; Humans; Kinetics; Leukemia; Male; Pentostatin; Ribonucleosides; Vidarabine

1983
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Acute Disease; Adenosine; Adult; Coformycin; Deoxyadenosines; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Homocysteine; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Vidarabine

1983
Effect of 2'-deoxycoformycin infusion on S-adenosylhomocysteine hydrolase and the amount of S-adenosylhomocysteine and related compounds in tissues of mice.
    Cancer research, 1983, Volume: 43, Issue:9

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Coformycin; Deoxyadenosines; Homocysteine; Hydrolases; Infusions, Parenteral; Jejunum; Kidney; Kinetics; Liver; Mice; Nucleoside Deaminases; Organ Specificity; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine

1983
The control of adenosine concentration in polymorphonuclear leucocytes, cultured heart cells and isolated perfused heart from the rat.
    The Biochemical journal, 1983, Aug-15, Volume: 214, Issue:2

    Topics: Adenosine; Adenosine Kinase; Animals; Cells, Cultured; Coformycin; Heart; In Vitro Techniques; Male; Myocardium; Neutrophils; Pentostatin; Perfusion; Rats; Rats, Inbred Strains; Tubercidin

1983
Enhancement of the antitumor activity of N6-(delta 2-isopentenyl)adenosine against cultured L-1210 leukemia cells by pentostatin using a polymeric delivery system.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:8

    Topics: Adenosine; Animals; Antineoplastic Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Coformycin; Drug Synergism; Isopentenyladenosine; Leukemia L1210; Mice; Pentostatin; Polymers; Ribonucleosides

1983
Neurotoxicity of deoxycoformycin: effect of constant infusion on adenosine deaminase, adenosine, 2'-deoxyadenosine and monoamines in the mouse brain.
    Neuropharmacology, 1983, Volume: 22, Issue:7

    Topics: Adenosine; Adenosine Deaminase; Animals; Biogenic Amines; Brain Chemistry; Coformycin; Deoxyadenosines; Dopamine; Mice; Norepinephrine; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Serotonin; Time Factors

1983
Increased cytotoxicity of N6-(delta 2-isopentenyl)adenosine in combination with pentostatin against L-1210 leukemia cells.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:10

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Division; Cells, Cultured; Coformycin; Isopentenyladenosine; Leukemia L1210; Mice; Pentostatin; Ribonucleosides

1983
The effects of adenosine and 2'-deoxycoformycin on sleep and wakefulness in rats.
    Neuropharmacology, 1983, Volume: 22, Issue:12A

    Topics: Adenosine; Adenosine Deaminase; Animals; Coformycin; Electroencephalography; Electromyography; Injections, Intraventricular; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides; Sleep; Sleep, REM; Wakefulness

1983
Evidence for the conversion of adenosine to 2'-deoxycoformycin by Streptomyces antibioticus.
    Biochemistry, 1984, Feb-28, Volume: 23, Issue:5

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Carbon Radioisotopes; Chromatography, Thin Layer; Coformycin; Cytarabine; Glycine; Pentostatin; Ribonucleosides; Streptomyces

1984
Stimulation of ATP synthesis in hypothermically perfused dog kidneys by adenosine and PO4.
    Cryobiology, 1984, Volume: 21, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coformycin; Cold Temperature; Dogs; Kidney; Mitochondria; Organ Preservation; Pentostatin; Perfusion; Phosphates; Potassium; Potassium Compounds

1984
Measurement of adenosine metabolism and uptake in smooth muscle and effects of adenosine transport inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:2

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Cattle; Coformycin; Coronary Vessels; Dipyridamole; Dose-Response Relationship, Drug; Female; Guanosine; Guinea Pigs; In Vitro Techniques; Inosine; Intestinal Mucosa; Male; Muscle, Smooth; Pentostatin; Rabbits; Thioinosine; Thionucleosides

1984
Inhibition of adenosine deaminase activity results in cytotoxicity to T lymphoblasts in vivo.
    Blood, 1980, Volume: 56, Issue:3

    Topics: Adenosine; Adolescent; Cell Survival; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Male; T-Lymphocytes

1980
Animal model for immune dysfunction associated with adenosine deaminase deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:8

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Coformycin; Disease Models, Animal; Immunity, Cellular; Immunologic Deficiency Syndromes; Mice; Nucleoside Deaminases; Pentostatin; Ribonucleosides; T-Lymphocytes

1980
Resistance of pokeweed mitogen-stimulated B cells to inhibition by deoxyadenosine.
    Clinical and experimental immunology, 1980, Volume: 41, Issue:1

    Topics: Adenosine; B-Lymphocytes; Cell Differentiation; Cell Line; Coformycin; Deoxyadenosines; Humans; Immunoglobulin G; Immunoglobulin M; Lymphocyte Activation; Pentostatin; Pokeweed Mitogens; T-Lymphocytes; Thymidine

1980
ATP depletion as a consequence of adenosine deaminase inhibition in man.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:10

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Aged; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Erythrocytes; Humans; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Sezary Syndrome

1980
An assay of deoxyadenosine and adenosine in human plasma by HPLC.
    Biochemical medicine, 1980, Volume: 24, Issue:2

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenosines; Humans; Kinetics; Pentostatin

1980
Adenosine stimulation of uphill adenine transport in L1210 leukemia cells. Evidence for a novel countertransport mechanism.
    The Journal of biological chemistry, 1981, May-10, Volume: 256, Issue:9

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Coformycin; Dipyridamole; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Pentostatin

1981
2-Deoxycoformycin inhibition of intracellular phosphorylation of adenosine in Novikoff rat hepatoma cells.
    Biochemical pharmacology, 1981, Mar-01, Volume: 30, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Membrane; Cells, Cultured; Coformycin; Deamination; Liver Neoplasms, Experimental; Pentostatin; Phosphorylation; Rats; Ribonucleosides

1981
Deoxycoformycin: neurological toxicity.
    Cancer chemotherapy and pharmacology, 1981, Volume: 5, Issue:3

    Topics: Adenosine; Adult; Coformycin; Deoxyadenosines; Electroencephalography; Humans; Male; Nervous System Diseases; Pentostatin; Ribonucleosides

1981
Levels of 2'-deoxycoformycin, adenosine, and deoxyadenosine in patients with acute lymphoblastic leukemia.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Adenosine; Adolescent; Adult; Child; Child, Preschool; Coformycin; Deoxyadenosines; Drug Evaluation; Female; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Time Factors

1981
Consequences of adenosine deaminase deficiency on thymocyte metabolism.
    European journal of immunology, 1981, Volume: 11, Issue:10

    Topics: Adenosine; Adenosine Deaminase; Animals; Coformycin; Concanavalin A; Deoxyadenosines; Dose-Response Relationship, Drug; Female; Lymphocyte Activation; Male; Nucleoside Deaminases; Pentostatin; Rats; Rats, Inbred Strains; T-Lymphocytes

1981
Comparison of the effects on cultured L1210 leukemia cells of the ribosyl, 2'-deoxyribosyl, and xylosyl homologs of tubercidin and adenosine alone or in combination with 2'-deoxycoformycin.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Adenosine; Amino Acids; Animals; Cell Division; Cell Survival; Cells, Cultured; Coformycin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Leukemia L1210; Mice; Mice, Inbred Strains; Nucleotides; Pentostatin; Ribonucleosides; Tubercidin

1982
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine
    Cellular immunology, 1982, Volume: 68, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins

1982
Renal handling of 2'-deoxyadenosine and adenosine in humans and mice.
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:2

    Topics: Adenine; Adenosine; Animals; Blood Proteins; Child, Preschool; Chromatography, High Pressure Liquid; Coformycin; Creatinine; Deoxyadenosines; Humans; Infant; Kidney; Male; Mice; Pentostatin; Protein Binding; Species Specificity

1982
Biochemical pharmacology and toxicology of 8-azaadenosine alone and in combination with 2'-deoxycoformycin (pentostatin).
    Biochemical pharmacology, 1982, Jul-15, Volume: 31, Issue:14

    Topics: Adenosine; Animals; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Coformycin; Drug Interactions; Female; Lethal Dose 50; Leukocyte Count; Liver; Male; Mice; Pentostatin; Rats; Ribonucleosides; Thymus Gland

1982
Pyrrolopyrimidine lethality in relation to ribonucleic acid synthesis in sarcoma 180 cells in vitro.
    Biochemical pharmacology, 1982, Aug-15, Volume: 31, Issue:16

    Topics: Adenosine; Animals; Cells, Cultured; Coformycin; Mice; Pentostatin; Pyrimidine Nucleosides; RNA, Neoplasm; Sarcoma 180; Time Factors; Uridine

1982
Adenosine and deoxyadenosine toxicity in colony assay systems for human T-lymphocytes, B-lymphocytes, and granulocytes.
    Cancer chemotherapy and pharmacology, 1982, Volume: 9, Issue:1

    Topics: Adenosine; B-Lymphocytes; Bone Marrow Cells; Cell Survival; Coformycin; Colony-Forming Units Assay; Deoxyadenosines; Granulocytes; Humans; Leukocytes; Pentostatin; T-Lymphocytes

1982
Activated T lymphocytes resist the toxic effects of the adenosine deaminase inhibitor, 2-deoxycoformycin.
    Cellular immunology, 1982, Sep-01, Volume: 72, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; B-Lymphocytes; Cell Differentiation; Coformycin; Concanavalin A; Cytotoxicity, Immunologic; Deoxyadenosines; Immunologic Memory; Lymphocyte Activation; Male; Nucleoside Deaminases; Rats; Ribonucleosides; T-Lymphocytes

1982
Capping and adenosine metabolism. Genetic and pharmacologic studies.
    The Journal of experimental medicine, 1980, Jan-01, Volume: 151, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Animals; Bone Marrow Transplantation; Coformycin; Contractile Proteins; Homocysteine; Humans; Immunologic Capping; Lymphocytes; Mice; Tubercidin

1980
Bone marrow transplantation only partially restores purine metabolites to normal in adenosine deaminase-deficient patients.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Bone Marrow Transplantation; Child; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Erythrocytes; Follow-Up Studies; Humans; Hydrolases; Monocytes; Nucleoside Deaminases; Pentostatin; Purines

1981
Potentiation of the myocardial actions of adenosine in the presence of coformycin, a specific inhibitor of adenosine deaminase.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 256, Issue:2

    Topics: Action Potentials; Adenosine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Dipyridamole; Drug Interactions; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Membrane Potentials; Myocardial Contraction; Nucleoside Deaminases; Ribonucleosides

1982
Apoptosis induced by adenosine in human leukemia HL-60 cells.
    Experimental cell research, 1994, Volume: 213, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Apoptosis; Cell Line; Coformycin; Deoxyadenosines; Deoxyguanosine; DNA, Neoplasm; Guanosine; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosomes; Poly Adenosine Diphosphate Ribose; Receptors, Purinergic P1; Thymidine; Tumor Cells, Cultured

1994
The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine.
    Cancer research, 1997, Jul-01, Volume: 57, Issue:13

    Topics: Adenosine; Animals; Coformycin; Colonic Neoplasms; Enzyme Inhibitors; Extracellular Space; Female; Fibrosarcoma; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Microdialysis; Neoplasm Transplantation; Time Factors; Tubercidin; Tumor Cells, Cultured

1997
Evidence for a low temperature transition state binding preference in bovine adenosine deaminase.
    Biophysical chemistry, 1998, Jan-01, Volume: 70, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Catalysis; Cattle; Coformycin; Cold Temperature; Enzyme Inhibitors; Kinetics; Protein Binding; Spleen; Temperature

1998
Delayed production of adenosine underlies temporal modulation of swimming in frog embryo.
    The Journal of physiology, 1998, Aug-15, Volume: 511 ( Pt 1)

    Topics: Adenosine; Adenosine Triphosphate; Animals; Coformycin; Embryo, Nonmammalian; Locomotion; Models, Biological; Models, Statistical; Motor Activity; Neurons; Spinal Cord; Swimming; Time Factors; Xenopus

1998
Adenosine, inosine, and guanosine protect glial cells during glucose deprivation and mitochondrial inhibition: correlation between protection and ATP preservation.
    Journal of neurochemistry, 1998, Volume: 71, Issue:2

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Amobarbital; Anaerobiosis; Animals; Astrocytes; Cell Hypoxia; Cell Survival; Coformycin; Dose-Response Relationship, Drug; Electron Transport; Enzyme Inhibitors; GABA Modulators; Glioma; Glucose; Glycolysis; Guanine Nucleotides; Guanosine; Hybrid Cells; Inosine; Inosine Monophosphate; Ischemia; Lactic Acid; Mitochondria; Neuroprotective Agents; Oligodendroglia; Pentosyltransferases; Purine Nucleosides; Rats

1998
The design and synthesis of inhibitors of adenosine 5'-monophosphate deaminase.
    Bioorganic & medicinal chemistry letters, 1999, Jul-19, Volume: 9, Issue:14

    Topics: Adenosine; Adenosine Triphosphate; AMP Deaminase; Coformycin; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Formycins; Herbicides; Inhibitory Concentration 50; Phosphorylation; Purine Nucleosides; Ribonucleosides; Structure-Activity Relationship

1999
Adenosine-mediated killing of cultured epithelial cancer cells.
    Cancer research, 2000, Apr-01, Volume: 60, Issue:7

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured

2000
Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice.
    The Journal of physiology, 2000, Jul-01, Volume: 526 Pt 1

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Biosensing Techniques; Calcium; Cell Hypoxia; Coformycin; Enzyme Inhibitors; Evaluation Studies as Topic; Excitatory Postsynaptic Potentials; Female; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Pentosyltransferases; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Synaptic Transmission; Xanthine Oxidase

2000
Enhancement of cellular adenosine triphosphate levels in PC12 cells by extracellular adenosine.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Coformycin; Dipyridamole; PC12 Cells; Rats; Receptors, Purinergic P1; Theophylline; Tubercidin

2002
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor.
    British journal of pharmacology, 2003, Volume: 140, Issue:6

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate

2003
Dominant localization of adenosine deaminase in leptomeninges and involvement of the enzyme in sleep.
    Biochemical and biophysical research communications, 2003, Dec-05, Volume: 312, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Brain; Coformycin; Extracellular Space; Male; Meninges; Prosencephalon; Rats; Sleep; Tissue Distribution

2003
Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Dec-16, Volume: 105, Issue:50

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase Inhibitors; Animals; Coformycin; Enzyme Inhibitors; Histamine; Hypothalamic Area, Lateral; Male; Mice; Mice, Knockout; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Histamine H1; Sleep Stages

2008
Coordinated Biosynthesis of the Purine Nucleoside Antibiotics Aristeromycin and Coformycin in Actinomycetes.
    Applied and environmental microbiology, 2018, 11-15, Volume: 84, Issue:22

    Topics: Actinobacteria; Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Coformycin; GMP Reductase; Purine Nucleosides

2018