coformycin has been researched along with adenine in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (85.37) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 2 (4.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cass, CE; Selner, M; Tan, TH | 1 |
| Lum, CT; Najarian, JS; Sutherland, DE | 1 |
| Alexander, L; Chubb, S; Loo, TL; Plunkett, W | 2 |
| Constine, J; Glazer, RI; Johns, DG | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Bontemps, F; Van den Berghe, G | 1 |
| Bonnafous, JC; Clofent, G; Dornand, J; Favero, J; Mani, JC | 1 |
| Frederiksen, S; Overgaard-Hansen, K; Svendsen, KR | 1 |
| Allan, PW; Bennett, LL; Brockman, RW; Rose, LM; Shaddix, SC | 1 |
| Bontemps, F; Hers, HG; Van den Berghe, G | 1 |
| Coleman, MS; Danton, MJ | 1 |
| Kontinen, VP; Pispa, JP | 1 |
| Gerber, G; Rapoport, I; Rapoport, SM | 1 |
| DeLong, RE; Phillis, JW; Towner, JK | 1 |
| Henderson, JF; Smith, CM; Zombor, G | 1 |
| Dóra, E | 1 |
| Wolberg, G; Zimmerman, TP | 1 |
| Archer, S; Chan, VL; Ho, JH; Juranka, PF | 1 |
| Hsiao, N; Lum, CT; Najarian, JS; Sutherland, DE | 1 |
| Plunkett, W | 1 |
| Seegmiller, JE | 1 |
| Miyamoto, T; Nishida, Y; Suzuki, S | 1 |
| Davis, JI; Fishbein, WN; Strong, DM; Winkert, JW | 1 |
| Behrman, HR; Brennan, TJ; Gore, SD; Ohkawa, R | 1 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G | 1 |
| Fairbanks, LD; Goday, A; Morris, GS; Simmonds, HA | 1 |
| Fox, RM; Kefford, RF | 1 |
| Baker, DC; Hanvey, JC; Hardman, JK; Suhadolnik, RJ | 1 |
| Cybulski, RL; Fry, DW; Goldman, ID | 1 |
| Coleman, MS; Deibel, MR; Hutton, JJ | 1 |
| Aye, MT; Dunne, JV | 1 |
| Ballow, M; Pantschenko, AG | 1 |
| Hirschhorn, R; Kuritsky, L; Ratech, H; Thorbecke, GJ | 1 |
| Kuttesch, JF; Nelson, JA | 1 |
| Berry, M; Buttin, G; Debatisse, M | 1 |
| Burrier, AC; Janero, DR; Sandhu, GS | 1 |
| Cristalli, G; Franchetti, P; Grifantini, M; La Colla, P; Marongiu, ME; Pani, A; Tinti, E | 1 |
| Appleman, JR; Bookser, BC; Erion, MD; Fujitaki, JM; Kasibhatla, SR; Probst, G; Xiao, W | 1 |
| Barry, CP; Lind, SE | 1 |
| Knowles, AF; Wen, LT | 1 |
1 review(s) available for coformycin and adenine
| Article | Year |
|---|---|
Overview of possible relation of defects in purine metabolism to immune deficiency.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; Humans; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Pentostatin; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors | 1985 |
1 trial(s) available for coformycin and adenine
| Article | Year |
|---|---|
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine | 1985 |
39 other study(ies) available for coformycin and adenine
| Article | Year |
|---|---|
Antiproliferative effects of 9-beta-D-arabinofuranosyladenine 5'-monophosphate and related compounds in combination with adenosine deaminase inhibitors against mouse leukemia L1210/C2 cells in culture.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Cell Division; Cells, Cultured; Coformycin; Drug Therapy, Combination; Leukemia L1210; Mice; Nucleoside Deaminases; Vidarabine Phosphate | 1979 |
Inhibition of PHA and NaI04 mitogenesis by the adenosine deaminase inhibitors erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) and 2-deoxycoformycin (2-dCF).
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cell Division; Cell Survival; Coformycin; Dogs; Leukocytes; Mice; Nucleoside Deaminases; Periodic Acid; Phytohemagglutinins; Rats; Ribonucleosides | 1979 |
Comparison of the activity of 2'-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl)adenine in vivo.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; DNA, Neoplasm; Female; Leukemia, Experimental; Mice; Nucleoside Deaminases; Ribonucleosides; Time Factors; Vidarabine | 1979 |
Biochemical basis of the increased activity of 9-beta-D-arabinofuranosyladenine in the presence of inhibitors of adenosine deaminase.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Bone Marrow; Cell Line; Coformycin; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred Strains; Nucleoside Deaminases; Ribonucleosides; Time Factors; Vidarabine | 1979 |
Adenosine deaminase inhibitors: differential effects on multiple forms of adenosine deaminase.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Coformycin; Intestines; Isoenzymes; Kinetics; Molecular Weight; Nucleoside Deaminases | 1978 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Mechanism of adenosine triphosphate catabolism induced by deoxyadenosine and by nucleoside analogues in adenosine deaminase-inhibited human erythrocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Coformycin; Deoxyadenosines; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Structure-Activity Relationship | 1989 |
Purine metabolizing enzymes of lymphocyte cell populations: correlation between AMP-deaminase activity and dATP accumulation in murine lymphocytes.
Topics: 5'-Nucleotidase; Adenine; Adenosine Monophosphate; AMP Deaminase; Animals; Bone Marrow; Cells, Cultured; Coformycin; Cytoplasm; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Lymph Nodes; Lymphocytes; Male; Mice; Nucleotidases; Nucleotide Deaminases; Pentostatin; Phosphotransferases; Spleen; Thymus Gland | 1985 |
Synergistic effect of 3'-deoxyadenosine N1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Drug Synergism; Female; Mice; Nucleoside Deaminases; Pentostatin; Ribonucleosides | 1988 |
Alterations in nucleotide pools induced by 3-deazaadenosine and related compounds. Role of adenylate deaminase.
Topics: Adenine; Adenosine Kinase; Alanine; Aminoglycosides; AMP Deaminase; Animals; Anti-Bacterial Agents; Cell Survival; Coformycin; Hypoxanthine; Hypoxanthines; Mice; Nucleotide Deaminases; Nucleotides; Time Factors; Tubercidin | 1988 |
Pathways of adenine nucleotide catabolism in human erythrocytes.
Topics: Adenine; Adenine Nucleotides; Adenosine; Blood Glucose; Coformycin; Erythrocytes; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Pentostatin; Phosphates; Tubercidin | 1986 |
Isolation of mutant adenosine deaminase by coformycin affinity chromatography.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Line; Chromatography, Affinity; Coformycin; Humans; Lymphocytes; Mutation; Nucleoside Deaminases; Pentostatin | 1986 |
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine | 1987 |
Degradation of AMP in erythrocytes of man. Evidence for a cytosolic phosphatase activity.
Topics: Acid Phosphatase; Adenine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Monophosphate; Chromatography, Gel; Coformycin; Cytosol; Deoxyadenosines; Erythrocytes; Humans; Hydrogen-Ion Concentration | 1987 |
Adenosine deaminase inhibitors enhance cerebral anoxic hyperemia in the rat.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Brain; Cerebrovascular Circulation; Coformycin; Hyperemia; Hypoxia, Brain; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides | 1985 |
Regulation of purine metabolism in lymphocytes.
Topics: Adenine; Adenosine Deaminase; Animals; B-Lymphocytes; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; Guanosine Triphosphate; Humans; Liver; Lymphocytes; Mice; Pentostatin; Plasma Cells; Purines; S-Adenosylhomocysteine; T-Lymphocytes; Thymus Gland | 1985 |
Adenosine and hypoxic vasodilatation.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cerebrovascular Circulation; Coformycin; Dogs; Hypoxia; Nucleoside Deaminases; Pentostatin; Rats; Ribonucleosides; Vasodilation | 1985 |
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic | 1985 |
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine | 1985 |
Relevance of adenosine deaminase to organ transplantation.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nucleoside Deaminases; Pentostatin; Skin Transplantation; Splenectomy; T-Lymphocytes; Vidarabine | 1985 |
Suppression by adenine compounds of histamine-induced contraction in isolated guinea pig tracheal rings.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Coformycin; Dipyridamole; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Trachea | 1982 |
Levels of adenosine deaminase AMP deaminase, and adenylate kinase in cultured human lymphoblast lines: exquisite sensitivity of AMP deaminase to adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenylate Kinase; AMP Deaminase; Cells, Cultured; Coformycin; Humans; Lymphocytes; Nucleoside Deaminases; Nucleotide Deaminases; Pentostatin; Phosphotransferases | 1981 |
Adenine-derived purines increase adenosine triphosphate (ATP) levels in the luteal cell: evidence that cell levels of ATP may limit the stimulation of adenosine 3',5'-monophosphate accumulation by luteinizing hormone.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Coformycin; Corpus Luteum; Cyclic AMP; Dinoprost; Dose-Response Relationship, Drug; Female; Luteinizing Hormone; Prostaglandins F; Purine Nucleosides; Rats | 1983 |
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides | 1983 |
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
Topics: Adenine; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; Dose-Response Relationship, Drug; Guanosine; Humans; Pentostatin; Purine-Nucleoside Phosphorylase; T-Lymphocytes | 1984 |
Purinogenic lymphocytotoxicity: clues to a wider chemotherapeutic potential for the adenosine deaminase inhibitors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenosines; Humans; Interphase; Leukemia; Lymphopenia; Nucleoside Deaminases; Pentostatin; Purines; Ribonucleosides; T-Lymphocytes | 1983 |
Evidence for the conversion of adenosine to 2'-deoxycoformycin by Streptomyces antibioticus.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Carbon Radioisotopes; Chromatography, Thin Layer; Coformycin; Cytarabine; Glycine; Pentostatin; Ribonucleosides; Streptomyces | 1984 |
Adenosine stimulation of uphill adenine transport in L1210 leukemia cells. Evidence for a novel countertransport mechanism.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Coformycin; Dipyridamole; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Pentostatin | 1981 |
Effect of adenosine deaminase inhibitors on the apparent rate of phosphorylation of deoxyadenosine.
Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Phosphorylation; Vidarabine | 1981 |
Effect of 2'-deoxycoformycin on erythroid, granulocytic, and T-lymphocyte colony growth.
Topics: Adenine; Adenosine Deaminase Inhibitors; Coformycin; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Erythrocytes; Granulocytes; Growth Inhibitors; Humans; Pentostatin; Phytohemagglutinins; Ribonucleosides; T-Lymphocytes | 1981 |
In vitro effects of adenosine deaminase inhibitors on lymphocyte mitogen responsiveness in the mouse.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cell Survival; Coformycin; Concanavalin A; Female; Horses; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Nucleoside Deaminases; Pentostatin; Phytohemagglutinins; Spleen; T-Lymphocytes | 1981 |
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins | 1982 |
Renal handling of 2'-deoxyadenosine and adenosine in humans and mice.
Topics: Adenine; Adenosine; Animals; Blood Proteins; Child, Preschool; Chromatography, High Pressure Liquid; Coformycin; Creatinine; Deoxyadenosines; Humans; Infant; Kidney; Male; Mice; Pentostatin; Protein Binding; Species Specificity | 1982 |
The potentiation of adenine toxicity to Chinese hamster cells by coformycin: suppression in mutants with altered regulation of purine biosynthesis or increased adenylate-deaminase activity.
Topics: Adenine; Adenosine Kinase; AMP Deaminase; Animals; Cell Line; Coformycin; Cricetinae; Drug Synergism; Fibroblasts; Inosine Monophosphate; Mutation; Nucleotide Deaminases; Purines; Ribonucleosides; Temperature | 1981 |
Adenosine deaminase inhibitors attenuate ischemic injury and preserve energy balance in isolated guinea pig heart.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Creatine Kinase; Energy Metabolism; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleosides; Phosphates | 1993 |
Enhancement of the anti-HIV-1 activity of ddAdo by coformycin, EHNA and deaza-EHNA derivatives.
Topics: Adenine; Adenosine Deaminase Inhibitors; Antiviral Agents; Cell Line; Coformycin; Dideoxyadenosine; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Inhibitors; HIV-1; Humans; Virus Replication | 1995 |
Design, synthesis, and structure-activity relationships of the first highly potent, selective, and bioavailable adenosine 5'-monophosphate deaminase inhibitors.
Topics: Adenine; Adenosine Monophosphate; Administration, Oral; AMP Deaminase; Biological Availability; Coformycin; Drug Design; Entropy; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Conformation; Molecular Structure; Structure-Activity Relationship | 1998 |
Adenosine-mediated killing of cultured epithelial cancer cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured | 2000 |
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate | 2003 |