Page last updated: 2024-08-22

coformycin and 9-(2-hydroxy-3-nonyl)adenine

coformycin has been researched along with 9-(2-hydroxy-3-nonyl)adenine in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (75.86)	18.7374
1990's	4 (13.79)	18.2507
2000's	2 (6.90)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (3.45)	2.80

Authors

Authors	Studies
Cunha, RA; Sebastião, AM	1
Bonnafous, JC; Clofent, G; Dornand, J; Favero, J; Mani, JC	1
Frederiksen, S; Overgaard-Hansen, K; Svendsen, KR	1
Coleman, MS; Danton, MJ	1
Kontinen, VP; Pispa, JP	1
Gerber, G; Rapoport, I; Rapoport, SM	1
DeLong, RE; Phillis, JW; Towner, JK	1
Dóra, E	1
Wolberg, G; Zimmerman, TP	1
Archer, S; Chan, VL; Ho, JH; Juranka, PF	1
Hsiao, N; Lum, CT; Najarian, JS; Sutherland, DE	1
Plunkett, W	1
Seegmiller, JE	1
Davis, JI; Fishbein, WN; Strong, DM; Winkert, JW	1
Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G	1
Fairbanks, LD; Goday, A; Morris, GS; Simmonds, HA	1
Fox, RM; Kefford, RF	1
Coleman, MS; Deibel, MR; Hutton, JJ	1
Aye, MT; Dunne, JV	1
Ballow, M; Pantschenko, AG	1
Hirschhorn, R; Kuritsky, L; Ratech, H; Thorbecke, GJ	1
Burrier, AC; Janero, DR; Sandhu, GS	1
Cristalli, G; Franchetti, P; Grifantini, M; La Colla, P; Marongiu, ME; Pani, A; Tinti, E	1
Barry, CP; Lind, SE	1
Knowles, AF; Wen, LT	1
Abushanab, E; Harriman, GC; Midgett, RM; Poirot, AF; Stoeckler, JD	1
Antonini, I; Cristalli, G; Franchetti, P; Grifantini, M; Lupidi, G; Martelli, S; Riva, F	1
Abushanab, E; Bastian, G; Bessodes, M; Chen, SF; Panzica, RP; Parks, RE; Stoeckler, JD	1
He, Y; Hou, R; Hou, S; Liao, C; Xie, Z; Yan, G	1

Reviews

2 review(s) available for coformycin and 9-(2-hydroxy-3-nonyl)adenine

Article	Year
Overview of possible relation of defects in purine metabolism to immune deficiency. Annals of the New York Academy of Sciences, 1985, Volume: 451 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; Humans; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Pentostatin; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors	1985
Zinc enzymes in medicinal chemistry. European journal of medicinal chemistry, 2021, Dec-15, Volume: 226 Topics: Chemistry, Pharmaceutical; Enzyme Inhibitors; Enzymes; Humans; Models, Molecular; Zinc	2021

Article

Year

Overview of possible relation of defects in purine metabolism to immune deficiency.

Annals of the New York Academy of Sciences, 1985, Volume: 451

Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; Humans; Immunologic Deficiency Syndromes; Immunosuppressive Agents; Pentostatin; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors

1985

Zinc enzymes in medicinal chemistry.

European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

Topics: Chemistry, Pharmaceutical; Enzyme Inhibitors; Enzymes; Humans; Models, Molecular; Zinc

2021

Trials

1 trial(s) available for coformycin and 9-(2-hydroxy-3-nonyl)adenine

Article	Year
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues. Annals of the New York Academy of Sciences, 1985, Volume: 451 Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine	1985

Article

Year

Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.

Annals of the New York Academy of Sciences, 1985, Volume: 451

Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine

1985

Other Studies

26 other study(ies) available for coformycin and 9-(2-hydroxy-3-nonyl)adenine

Article	Year
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog. European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1 Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine	1991
Purine metabolizing enzymes of lymphocyte cell populations: correlation between AMP-deaminase activity and dATP accumulation in murine lymphocytes. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 179, Issue:4 Topics: 5'-Nucleotidase; Adenine; Adenosine Monophosphate; AMP Deaminase; Animals; Bone Marrow; Cells, Cultured; Coformycin; Cytoplasm; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Lymph Nodes; Lymphocytes; Male; Mice; Nucleotidases; Nucleotide Deaminases; Pentostatin; Phosphotransferases; Spleen; Thymus Gland	1985
Synergistic effect of 3'-deoxyadenosine N1-oxide and adenosine deaminase inhibitors on growth of Ehrlich ascites tumor cells in vivo. Cancer chemotherapy and pharmacology, 1988, Volume: 21, Issue:1 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Drug Resistance; Drug Synergism; Female; Mice; Nucleoside Deaminases; Pentostatin; Ribonucleosides	1988
Isolation of mutant adenosine deaminase by coformycin affinity chromatography. Analytical biochemistry, 1986, Nov-15, Volume: 159, Issue:1 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Line; Chromatography, Affinity; Coformycin; Humans; Lymphocytes; Mutation; Nucleoside Deaminases; Pentostatin	1986
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation. Molecular and cellular biochemistry, 1987, Volume: 76, Issue:1 Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine	1987
Degradation of AMP in erythrocytes of man. Evidence for a cytosolic phosphatase activity. Biomedica biochimica acta, 1987, Volume: 46, Issue:5 Topics: Acid Phosphatase; Adenine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Monophosphate; Chromatography, Gel; Coformycin; Cytosol; Deoxyadenosines; Erythrocytes; Humans; Hydrogen-Ion Concentration	1987
Adenosine deaminase inhibitors enhance cerebral anoxic hyperemia in the rat. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1985, Volume: 5, Issue:2 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Brain; Cerebrovascular Circulation; Coformycin; Hyperemia; Hypoxia, Brain; Male; Pentostatin; Rats; Rats, Inbred Strains; Ribonucleosides	1985
Adenosine and hypoxic vasodilatation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1985, Volume: 5, Issue:4 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cerebrovascular Circulation; Coformycin; Dogs; Hypoxia; Nucleoside Deaminases; Pentostatin; Rats; Ribonucleosides; Vasodilation	1985
Effects of adenosine deaminase inhibitors on lymphocyte-mediated cytolysis. Annals of the New York Academy of Sciences, 1985, Volume: 451 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Line; Coformycin; Cytotoxicity, Immunologic; Immunity, Cellular; Immunosuppressive Agents; Leukemia; Mice; Nucleoside Deaminases; Pentostatin; T-Lymphocytes, Cytotoxic	1985
An analysis of multiple mechanisms of adenosine toxicity in baby hamster kidney cells. Journal of cellular physiology, 1985, Volume: 124, Issue:2 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Cell Adhesion; Cell Line; Coformycin; Drug Resistance; Drug Synergism; Guinea Pigs; Homocysteine; Kidney; Nucleotides; Pentostatin; Ribonucleotide Reductases; S-Adenosylhomocysteine; Uridine	1985
Relevance of adenosine deaminase to organ transplantation. Annals of the New York Academy of Sciences, 1985, Volume: 451 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nucleoside Deaminases; Pentostatin; Skin Transplantation; Splenectomy; T-Lymphocytes; Vidarabine	1985
Levels of adenosine deaminase AMP deaminase, and adenylate kinase in cultured human lymphoblast lines: exquisite sensitivity of AMP deaminase to adenosine deaminase inhibitors. Biochemical medicine, 1981, Volume: 26, Issue:3 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenylate Kinase; AMP Deaminase; Cells, Cultured; Coformycin; Humans; Lymphocytes; Nucleoside Deaminases; Nucleotide Deaminases; Pentostatin; Phosphotransferases	1981
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. The Journal of experimental medicine, 1983, Oct-01, Volume: 158, Issue:4 Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides	1983
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine. Clinical and experimental immunology, 1984, Volume: 56, Issue:1 Topics: Adenine; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; Dose-Response Relationship, Drug; Guanosine; Humans; Pentostatin; Purine-Nucleoside Phosphorylase; T-Lymphocytes	1984
Purinogenic lymphocytotoxicity: clues to a wider chemotherapeutic potential for the adenosine deaminase inhibitors. Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:2 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenosines; Humans; Interphase; Leukemia; Lymphopenia; Nucleoside Deaminases; Pentostatin; Purines; Ribonucleosides; T-Lymphocytes	1983
Effect of adenosine deaminase inhibitors on the apparent rate of phosphorylation of deoxyadenosine. Biochemical medicine, 1981, Volume: 25, Issue:3 Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Phosphorylation; Vidarabine	1981
Effect of 2'-deoxycoformycin on erythroid, granulocytic, and T-lymphocyte colony growth. Blood, 1981, Volume: 58, Issue:5 Topics: Adenine; Adenosine Deaminase Inhibitors; Coformycin; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Erythrocytes; Granulocytes; Growth Inhibitors; Humans; Pentostatin; Phytohemagglutinins; Ribonucleosides; T-Lymphocytes	1981
In vitro effects of adenosine deaminase inhibitors on lymphocyte mitogen responsiveness in the mouse. Cellular immunology, 1981, Volume: 64, Issue:1 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cell Survival; Coformycin; Concanavalin A; Female; Horses; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Nucleoside Deaminases; Pentostatin; Phytohemagglutinins; Spleen; T-Lymphocytes	1981
Suppression of human lymphocyte DNA and protein synthesis in vitro by adenosine and eight modified adenine nucleosides in the presence or in the absence of adenosine deaminase inhibitors, 2'-deoxycoformycin (DCF) and erythro-9-(2-hydroxy-3-nonyl) adenine Cellular immunology, 1982, Volume: 68, Issue:2 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Blood Proteins; Coformycin; DNA; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Pentostatin; Phytohemagglutinins	1982
Adenosine deaminase inhibitors attenuate ischemic injury and preserve energy balance in isolated guinea pig heart. The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Creatine Kinase; Energy Metabolism; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleosides; Phosphates	1993
Enhancement of the anti-HIV-1 activity of ddAdo by coformycin, EHNA and deaza-EHNA derivatives. The new microbiologica, 1995, Volume: 18, Issue:4 Topics: Adenine; Adenosine Deaminase Inhibitors; Antiviral Agents; Cell Line; Coformycin; Dideoxyadenosine; Drug Evaluation, Preclinical; Drug Synergism; Enzyme Inhibitors; HIV-1; Humans; Virus Replication	1995
Adenosine-mediated killing of cultured epithelial cancer cells. Cancer research, 2000, Apr-01, Volume: 60, Issue:7 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Coformycin; Deoxyadenosines; Dipyridamole; Enzyme Inhibitors; Female; Humans; Kinetics; Ovarian Neoplasms; Pentostatin; Tumor Cells, Cultured	2000
Extracellular ATP and adenosine induce cell apoptosis of human hepatoma Li-7A cells via the A3 adenosine receptor. British journal of pharmacology, 2003, Volume: 140, Issue:6 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Division; Cell Line; Cell Line, Tumor; Coformycin; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Nucleosides; Oligonucleotide Array Sequence Analysis; Receptor, Adenosine A3; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Uridine Triphosphate	2003
Adenosine deaminase inhibitors. Synthesis and biological evaluation of C1' and nor-C1' derivatives of (+)-erythro-9-(2(S)-hydroxy-3(R)-nonyl)adenine. Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22 Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Binding Sites; Cattle; In Vitro Techniques; Stereoisomerism; Structure-Activity Relationship	1992
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine. Journal of medicinal chemistry, 1984, Volume: 27, Issue:3 Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cattle; Intestines; Nucleoside Deaminases	1984
Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines. Journal of medicinal chemistry, 1981, Volume: 24, Issue:12 Topics: Adenine; Adenosine Deaminase Inhibitors; Chemical Phenomena; Chemistry; Nucleoside Deaminases	1981