Page last updated: 2024-08-22

coformycin and 2'-deoxyadenosine triphosphate

coformycin has been researched along with 2'-deoxyadenosine triphosphate in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199029 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Begleiter, A; Cavers, DJ; Israels, LG; Johnston, JB; Leith, MK; Pugh, L; Wilkins, JA1
Dietz, G; Ganeshaguru, K; Ho, AD; Hoffbrand, AV; Hunstein, W; Knauf, W; Trede, I1
Matsumoto, SS; Yu, AL; Yu, J1
Begleiter, A; Israels, LG; Johnston, JB; Pugh, L1
Cohen, A; Thompson, E1
Buc, HA; Garreau, F; Hamet, M; Moncion, A; PĂ©rignon, JL; Thuillier, L1
Bluestein, HG; Cohen, AH; Firestein, GS; Gruber, HE; Redelman, D1
Heike, T; Katamura, K; Kubota, M; Mikawa, H; Shinomiya, K2
Begleiter, A; Glazer, RI; Israels, LG; Johnston, JB; Pugh, L1
Catovsky, D; Ganeshaguru, K; Ho, AD; Hoffbrand, AV; Piga, A1
Fairbanks, LD; Goday, A; Morris, GS; Simmonds, HA2
Kimura, K; Tanaka, M1
Benjamin, RS; Freireich, EJ; Keating, MJ; Plunkett, W1
Coleman, MS; Siaw, MF1
Hirschhorn, R; Ratech, H; Thorbecke, GJ1
Berkowitz, LR; Koller, CA; Mulhern, AT; Orringer, EP1
Barankiewicz, J; Cohen, A1
Fairbanks, LD; Goday, A; Levinsky, RJ; Morris, GS; Simmonds, HA1
Kang, GJ; Kimball, AP1
Goday, A; Hoffbrand, AV; Levinsky, RJ; Simmonds, HA; Watson, AR; Webster, DR1
Ackland, SP; Bagnara, AS; Hallam, LJ; Van der Weyden, MB; Whiteside, MG1
Alvarez, A; Bakay, B; Bleeker, L; Kung, F; Matsumoto, S; Nyhan, WL; Yu, AL1
Lukey, T; Snyder, FF1
Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF1
Fox, RM; Kefford, RF1
Henderson, JF; Smith, CM1
Ganeshaguru, K; Hoffbrand, AV; Murphy, P; Piga, A; Prentice, HG; Russell, NH; Sylwestrowicz, T1

Other Studies

29 other study(ies) available for coformycin and 2'-deoxyadenosine triphosphate

ArticleYear
Biochemical changes induced in hairy-cell leukemia following treatment with the adenosine deaminase inhibitor 2'-deoxycoformycin.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 2

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Aged; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Humans; Interferons; Leukemia, Hairy Cell; Leukocyte Count; Male; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1986
Enzyme activities of leukemic cells and biochemical changes induced by deoxycoformycin in vitro--lack of correlation with clinical response.
    Leukemia research, 1989, Volume: 13, Issue:4

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Adenosylhomocysteinase; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; DNA Damage; Humans; Hydrolases; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; NAD; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1989
The effect of deoxyadenosine plus deoxycoformycin on replicative and repair synthesis of DNA in human lymphoblasts and isolated nuclei.
    The Journal of biological chemistry, 1988, May-25, Volume: 263, Issue:15

    Topics: Cell Line; Cell Nucleus; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Repair; DNA Replication; Humans; Kinetics; Pentostatin; Ribonucleosides; T-Lymphocytes

1988
Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; DNA Repair; Drug Synergism; Leukemia L5178; Leukemia, Experimental; Leukemia, Lymphoid; Mice; NAD; Pentostatin; Ribonucleosides

1988
DNA repair in nondividing human lymphocytes: inhibition by deoxyadenosine.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Repair; Humans; Lymphocyte Activation; Lymphocytes; Methylnitronitrosoguanidine; Pentostatin

1986
Energy metabolism in adenosine deaminase-inhibited human erythrocytes.
    Clinica chimica acta; international journal of clinical chemistry, 1986, Apr-15, Volume: 156, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Energy Metabolism; Erythrocytes; Glycolysis; Humans; Hypoxanthine; Hypoxanthines; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1986
Deoxy-ATP accumulation in adenosine deaminase-inhibited human B and T lymphocytes.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adenosine Deaminase Inhibitors; B-Lymphocytes; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Lymphocyte Activation; Nucleoside Deaminases; Pentostatin; T-Lymphocytes

1986
Inhibitor of 2', 5'-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 2',5'-Oligoadenylate Synthetase; Adenosine; Cell Line; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Enzyme Induction; Homocysteine; Humans; Interferon Type I; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine

1986
Induction of DNA strand breaks in chronic lymphocytic leukemia following treatment with 2'-deoxycoformycin in vivo and in vitro.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenosine Deaminase Inhibitors; Aged; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Humans; Leukemia, Lymphoid; Male; Middle Aged; Monocytes; NAD; Pentostatin; Ribonucleosides

1987
Biochemical mechanisms of deoxycoformycin toxicity in chronic leukemias.
    Leukemia research, 1987, Volume: 11, Issue:10

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; Humans; Leukemia, Lymphoid; NAD; Pentostatin; Ribonucleosides

1987
Inhibitor of 2',5'-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon.
    Biochemical and biophysical research communications, 1985, Mar-29, Volume: 127, Issue:3

    Topics: 2',5'-Oligoadenylate Synthetase; Adenosine Deaminase; Cell Line; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Enzyme Induction; Exoribonucleases; Humans; Immunologic Deficiency Syndromes; Interferon Type I; Pentostatin; Ribonucleosides; T-Lymphocytes

1985
Human B lymphocytes and thymocytes but not peripheral blood mononuclear cells accumulate high dATP levels in conditions simulating ADA deficiency.
    Biochemical pharmacology, 1985, Oct-01, Volume: 34, Issue:19

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; B-Lymphocytes; Cell Line; Child; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Guanosine Triphosphate; Humans; Nucleoside Deaminases; Palatine Tonsil; Pentostatin; Plasma Cells; T-Lymphocytes; Thymus Gland

1985
Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin.
    The Tohoku journal of experimental medicine, 1985, Volume: 147, Issue:4

    Topics: Acute Disease; B-Lymphocytes; Cell Line; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Growth Inhibitors; Humans; Leukemia; Leukemia, Experimental; Leukemia, Myeloid; Pentostatin; Ribonucleosides; T-Lymphocytes; Thymidine

1985
Modulation of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and deoxyadenosine triphosphate in leukemic cells by 2'-deoxycoformycin during therapy with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Adult; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; DNA; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine; Vidarabine Phosphate

1982
In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA.
    The Journal of biological chemistry, 1984, Aug-10, Volume: 259, Issue:15

    Topics: Adenosine Deaminase Inhibitors; Adenosine Kinase; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine Kinase; DNA; Humans; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; RNA; T-Lymphocytes; Vidarabine

1984
Metabolic abnormalities of human adenosine deaminase deficiency reproduced in the mouse by 2'-deoxycoformycin, and adenosine deaminase inhibitor.
    Clinical immunology and immunopathology, 1981, Volume: 21, Issue:1

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Body Weight; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Hydrolases; Mice; Mice, Inbred Strains; Nucleoside Deaminases; Organ Size; Pentostatin; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Thymus Gland

1981
Role of glycolysis in deoxyadenosine induced ATP depletion and dATP accumulation in red cells.
    Progress in clinical and biological research, 1984, Volume: 165

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Erythrocytes; Glycolysis; Humans; In Vitro Techniques; Pentostatin

1984
Evidence for distinct catabolic pathways of adenine ribonucleotides and deoxyribonucleotides in human T lymphoblastoid cells.
    The Journal of biological chemistry, 1984, Dec-25, Volume: 259, Issue:24

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Coformycin; Deoxyadenine Nucleotides; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine; Kinetics; Pentostatin; Structure-Activity Relationship; T-Lymphocytes

1984
dATP accumulation and ATP depletion in platelets in adenosine deaminase deficiency: significance for the immune response?
    Bioscience reports, 1984, Volume: 4, Issue:10

    Topics: Adenosine Deaminase; Adenosine Triphosphate; Blood Platelets; Coformycin; Deoxyadenine Nucleotides; Humans; Immunologic Deficiency Syndromes; Nucleoside Deaminases; Nucleotides; Pentostatin

1984
Dipyridamole enhancement of toxicity to L1210 cells by deoxyadenosine and deoxycoformycin combinations in vitro.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Survival; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Dipyridamole; Drug Therapy, Combination; Leukemia L1210; Mice; Pentostatin; Ribonucleosides; Ribonucleotide Reductases

1984
Importance of platelet-free preparations for evaluating lymphocyte nucleotide levels in inherited or acquired immunodeficiency syndromes.
    Clinical science (London, England : 1979), 1983, Volume: 65, Issue:6

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Separation; Child; Coformycin; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Immunologic Deficiency Syndromes; Lymphocytes; Pentostatin; Purine-Nucleoside Phosphorylase

1983
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
    Clinical and experimental immunology, 1984, Volume: 56, Issue:1

    Topics: Adenine; Adenosine Deaminase Inhibitors; B-Lymphocytes; Cell Line; Cell Survival; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyguanine Nucleotides; Deoxyguanosine; Dose-Response Relationship, Drug; Guanosine; Humans; Pentostatin; Purine-Nucleoside Phosphorylase; T-Lymphocytes

1984
The biochemical and clinical consequences of 2'-deoxycoformycin in T cell chronic lymphocytic leukaemia.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:1

    Topics: Adenosine Deaminase; Adenosine Triphosphate; Adenosylhomocysteinase; AMP Deaminase; Coformycin; Cytotoxicity, Immunologic; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Hydrolases; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Ribonucleosides; T-Lymphocytes

1984
Biochemical basis for the differential effects of deoxycoformycin on human leukemias.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; DNA Replication; Humans; Leukemia; Pentostatin; Ribonucleosides

1984
S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice.
    Biochemical pharmacology, 1983, Apr-15, Volume: 32, Issue:8

    Topics: Adenosylhomocysteinase; Age Factors; Animals; Coformycin; Deoxyadenine Nucleotides; Erythrocytes; Hydrolases; Lymphocyte Activation; Lymphocytes; Mice; Ribonucleosides; Spleen; Thymus Gland

1983
Studies on the biochemical sequelae of therapy in Thy-acute lymphoblastic leukaemia with the adenosine deaminase inhibitor 2' deoxycoformycin.
    British journal of haematology, 1981, Volume: 49, Issue:1

    Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydrolases; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Ribonucleosides; Thymine Nucleotides

1981
Deoxycoformycin-induced response in chronic lymphocytic leukaemia: deoxyadenosine toxicity in non-replicating lymphocytes.
    British journal of haematology, 1982, Volume: 50, Issue:4

    Topics: Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Replication; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Pentostatin; Ribonucleosides

1982
Deoxyadenosine triphosphate accumulation in erythrocytes of deoxycoformycin-treated mice.
    Biochemical pharmacology, 1982, Apr-15, Volume: 31, Issue:8

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Deoxyadenine Nucleotides; Disease Models, Animal; Erythrocytes; Mice; Nucleoside Deaminases; Pentostatin; Ribonucleosides

1982
The effect of deoxycoformycin and deoxyadenosine on deoxyribonucleotide concentrations in leukaemic cells.
    British journal of haematology, 1982, Volume: 51, Issue:4

    Topics: Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyribonucleotides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Pentostatin; Ribonucleosides; T-Lymphocytes

1982