coenzyme a has been researched along with pantetheine in 88 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (36.36) | 18.7374 |
1990's | 7 (7.95) | 18.2507 |
2000's | 21 (23.86) | 29.6817 |
2010's | 24 (27.27) | 24.3611 |
2020's | 4 (4.55) | 2.80 |
Authors | Studies |
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Brohn, FH; Trager, W | 1 |
Knowles, CL; Lyman, EM; Sribney, M | 1 |
Halvorsen, O; Skrede, S | 1 |
Kumar, S | 1 |
Fazakerley, GV; Linder, PW; Reid, DG | 1 |
Cebe, M; Perahia, D | 1 |
Bazzone, TJ; Kuo, CH; Rinaldi, PL; Wilson, GE | 1 |
Jenik, RA; Kim, M; Lornitzo, FA; Porter, JW; Qureshi, AA | 1 |
Master, BS; Roeder, SB; Stewart, CJ | 1 |
Utno, LIa | 1 |
Neely, JR; Tahiliani, AG | 1 |
Fierke, CA; Jencks, WP | 1 |
Hobara, N; Nagashima, H; Watanabe, A | 1 |
Gurinovich, VA; Moiseenok, AG; Sheibak, VM | 1 |
Graves, CP; Hansen, RG; Jorgensen, E; Peterson, MA; Thoene, JG; Wilson, DE; Windham, CT; Wittwer, CT; Wyse, BW | 1 |
Burton, DN; Yu, HL | 1 |
Jackowski, S; Rock, CO | 2 |
Branca, D; Scutari, G; Siliprandi, N | 1 |
Gross, CJ; Henderson, LM; Shibata, K | 1 |
Floridi, S; Mei, V; Pranzetti, P; Valora, N | 1 |
Katiyar, SS; Pan, D; Porter, JW | 2 |
Ahmad, F; Ahmad, PM; Feltman, DS | 1 |
Hansen, RG; Wittwer, C; Wyse, B | 1 |
Davis, PS; Sharma, DC; Sharma, PK | 1 |
Keefe, AD; Miller, SL; Newton, GL | 1 |
von Döhren, H | 1 |
Moiseenok, AG; Rakowska, M; Slyshenkov, VS; Wojtczak, L | 1 |
Drueckhammer, DG; Gehring, AM; Lambalot, RH; Vogel, KW; Walsh, CT | 1 |
Bucovaz, ET; Macleod, RM; Morrison, JC; Whybrew, WD | 1 |
Jakubowski, H | 1 |
Ehmann, DE; Keating, TA; Suo, Z; Walsh, CT | 1 |
Kleinkauf, H | 1 |
Coutadeur, MC; Franchi, J; Kupferberg, A; Marteau, C; Mersel, M | 1 |
Blaesse, M; Jung, G; Kupke, T; Schmid, D; Steinbacher, S; Uebele, M | 1 |
Bugg, CW; Huang, F; Yarus, M | 1 |
Culianez-Macia, FA; Hernandez-Acosta, P; Kupke, T; Steinbacher, S | 1 |
Begley, TP; Strauss, E | 1 |
Bhattacharjee, JK; Evans, SA; Guo, S; Wilkes, MB | 1 |
Dunaway-Mariano, D; Luo, L; Taylor, KL; Wei, Y; Xiang, H; Zhang, W | 1 |
Archambault, A; Carey, PR; Dong, J; Dunaway-Mariano, D; Song, F; Taylor, K; Zhang, W; Zhuang, Z | 1 |
Culiáñez-Macià, FA; Hernández-Acosta, P; Kupke, T | 1 |
HOAGLAND, MB; NOVELLI, GD | 1 |
BRIGNON, J; DUBOST, S; WOLFF, R | 1 |
BRIGNON, JJ; DUBOST, S; WOLFF, RL | 1 |
REEVES, RE | 1 |
ALBERTS, AW; MAJERUS, PW; VAGELOS, PR | 1 |
CAVALLA, JF | 1 |
CRAIG, JA; SNELL, EE | 1 |
Burkart, MD; Clarke, KM; La Clair, JJ; Mercer, AC | 1 |
Alejandro, S; Gonzalez-Guzman, M; Graham, IA; Larson, TR; Rodriguez, PL; Rubio, S; Serrano, R | 1 |
Burkart, MD; Meier, JL; Mercer, AC; Rivera, H | 1 |
Kaganman, I | 1 |
Case, H; de Dreu, P; Miller, JR; Mueller, WT; Ohren, J; Sarver, RW; Thanabal, V | 1 |
Burkart, MD; Haushalter, RW; Hur, GH; Worthington, AS | 1 |
Bodner, MJ; Freeman, MF; Li, R; Moshos, KA; Townsend, CA | 1 |
Burkart, MD; Hur, GH; Meier, JL; Mercer, AC; Smith, AR | 1 |
Doyle, S; Frizzell, A; Stack, D; Tomkins, K | 1 |
Horváth, Z; Vécsei, L | 1 |
Bhagawati, M; Brunk, A; Paterok, D; Piehler, J; Podoplelova, Y; Reichel, A; Waichman, S | 1 |
Hayflick, S; Kayser, O; Muntendam, R; Rana, A; Reijngoud, DJ; Seinen, E; Sibon, OC; Siudeja, K; Srinivasan, B; van der Want, JJ | 1 |
Mesecar, AD; Wubben, TJ | 1 |
Hughes, AJ; Keatinge-Clay, A | 1 |
Kang, JY; Lee, HH; Mikami, B; Suh, SW; Yoon, HJ | 1 |
de Jong, J; Hayflick, S; Jackowski, S; Nollen, EA; Rana, A; Sanford, L; Sibon, OC; Siudeja, K; Srinivasan, B; Xu, L | 1 |
Borgaro, JG; Chang, A; Machutta, CA; Tonge, PJ; Zhang, X | 1 |
Abraham, LJ; Blangero, J; Kaskow, BJ; Michael Proffit, J; Moses, EK; Proffitt, JM | 1 |
Auclair, K; Tam, IS; Vong, K; Yan, X | 1 |
Burkart, MD; Chapman, E; Kang, M; Kelleher, NL; La Clair, JJ; Ntai, I; Rothmann, M; Villa, R | 1 |
Fukuwatari, T; Kaneko, M; Shibata, K | 1 |
Nitto, T; Onodera, K | 1 |
Chang, SY; Chen, T; Cheng, CS; Jia, KF; Lin, MS; Yin, HS | 1 |
Sandberg, M; Weber, SG; Wu, J | 1 |
Bettencourt, C; Chiapparini, L; Demchenko, N; Dusi, S; Garavaglia, B; Goffrini, P; Gout, I; Gregory, A; Haack, TB; Hamada, J; Hayflick, S; Houlden, H; Invernizzi, F; Kurian, MA; Nardocci, N; Pasqualato, S; Prokisch, H; Sanford, L; Schwarzmayr, T; Strom, TM; Tigano, M; Tiranti, V; Tsuchiya, Y; Valletta, L; Venco, P; Wieland, T; Zorzi, G | 1 |
Atomi, H; Imanaka, T; Ishibashi, T; Kishimoto, A; Kita, A; Miki, K; Tomita, H; Yokooji, Y | 1 |
Cao, R; Chen, C; Li, P; Maurmann, L; Zhang, W | 1 |
Baratashvili, M; Colombelli, C; Grzeschik, NA; Hayflick, S; Kanon, B; Kosec, G; Lambrechts, RA; Nollen, EA; Petković, H; Podgoršek, A; Reijngoud, DJ; Schaap, O; Sibon, OC; Srinivasan, B; Tiranti, V; van der Zwaag, M | 1 |
de Villiers, M; Strauss, E | 1 |
Sibon, OC; Strauss, E | 1 |
Huang, F; Sapkota, K | 1 |
Abudi, S; Alhaddad, B; Anikster, Y; Avivi, C; Barel, O; Barshack, I; Berutti, R; Braunisch, M; Brundel, BJJM; Dubnov-Raz, G; Eyal, E; Grigat, M; Grzeschik, NA; Haack, TB; Haas, D; Hoffmann, GF; Iuso, A; Kanon, B; Kumbar, M; Marek-Yagel, D; Mastantuono, E; Meitinger, T; Messias, AC; Okun, JG; Perles, Z; Pode-Shakked, B; Prokisch, H; Rubinshtein, M; Salem, Y; Schüller, HJ; Schwarzmayr, T; Sibon, OCM; Strom, TM; Terrile, C; Tirosh, T; Vardi, A; Volkov, A; Wiersma, M | 1 |
Basak, A; Biswas, R; Das, AK; Das, PK; Dutta, D; Maiti, MK; Singh, BK | 1 |
Cobb, J; Duffy, M; Fox, R; Freed, A; Gray, N; Gregory, AM; Hamada, J; Hayflick, SJ; Hogarth, P; Jeong, SY; Jin, H; Lambrechts, R; Nilsen, A; Pham, T; Placzek, A; Rai, P; Ralle, M; Schwanemann, L; Sibon, OC; van der Zwaag, M; Wakeman, K; Woltjer, RL; Zhen, D | 1 |
Allan, H; Bellany, F; Chan, AWE; Gout, I; Tabor, AB; Tran, TM; Tsuchiya, Y | 1 |
Chen, N; Wang, C | 1 |
Dhembla, C; Kundu, S; Sundd, M; Yadav, U | 1 |
Ackenhusen, SE; Chun, SW; Narayan, ARH; Wang, Y | 1 |
5 review(s) available for coenzyme a and pantetheine
Article | Year |
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The organization of multifunctional peptide and depsipeptide synthetases.
Topics: Adenosine Monophosphate; Amino Acid Sequence; Binding Sites; Coenzyme A; Molecular Sequence Data; Multienzyme Complexes; Pantetheine; Peptide Biosynthesis; Peptide Synthases; Peptides | 1993 |
Current medical aspects of pantethine.
Topics: Acetylcholine; Animals; Antioxidants; Atherosclerosis; Blood Platelets; Cataract; Central Nervous System; Coenzyme A; Cystine; Cystinosis; Dietary Carbohydrates; Fatty Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Oxidation-Reduction; Pantetheine; Pantothenic Acid; Pyruvates | 2009 |
Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases.
Topics: Amidohydrolases; Amino Acid Sequence; Animals; Cardiovascular Diseases; Cell Membrane; Coenzyme A; GPI-Linked Proteins; Humans; Inflammation; Mice; Molecular Sequence Data; Pantetheine; Pantothenic Acid | 2012 |
Linkage between coenzyme a metabolism and inflammation: roles of pantetheinase.
Topics: Amidohydrolases; Animals; Cell Adhesion Molecules; Coenzyme A; Cysteamine; Disease Progression; GPI-Linked Proteins; Humans; Hydrolysis; Inflammation; Macrophage-1 Antigen; Multigene Family; Neutrophils; Oxidative Stress; Pantetheine; Pantothenic Acid; Proteolysis | 2013 |
Chemical Labeling of Protein 4'-Phosphopantetheinylation.
Topics: Coenzyme A; Models, Molecular; Molecular Structure; Pantetheine; Protein Processing, Post-Translational | 2021 |
83 other study(ies) available for coenzyme a and pantetheine
Article | Year |
---|---|
Coenzyme A requirement of malaria parasites: enzymes of coenzyme A biosynthesis in normal duck erythrocytes and erythrocytes infected with Plasmodium lophurae.
Topics: Adenosine Triphosphate; Animals; Carboxy-Lyases; Coenzyme A; Cysteine; Erythrocytes; Nucleotidyltransferases; Pantetheine; Pantothenic Acid; Peptide Synthases; Phosphotransferases; Plasmodium | 1975 |
Regulation of phosphatidylcholine synthesis in rat liver endoplasmic reticulum.
Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Coenzyme A; Cystamine; Cysteamine; Diacylglycerol Cholinephosphotransferase; Endoplasmic Reticulum; Liver; Manganese; Nucleotides; Pantetheine; Pantothenic Acid; Phosphatidylcholines; Rats | 1976 |
Mitochondrial biosynthesis of coenzyme A.
Topics: Animals; Carboxy-Lyases; Coenzyme A; Kinetics; Ligases; Male; Mitochondria, Liver; Nucleotidyltransferases; Pantetheine; Pantothenic Acid; Phosphotransferases; Rats | 1979 |
Functional deacylases of pigeon liver fatty acid synthetase complex.
Topics: Acetyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Carbon Dioxide; Carbon Radioisotopes; Coenzyme A; Columbidae; Cysteamine; Fatty Acid Synthases; Hydrogen-Ion Concentration; Kinetics; Liver; Malonates; Palmitic Acids; Pantetheine; Phenylmethylsulfonyl Fluoride; Sulfones | 1975 |
Determination of the solution conformation of dephospho coenzyme A by nuclear-magnetic-resonance spectroscopy with lanthanide probes. A method for analysis when more than one complex species is present.
Topics: Adenosine; Coenzyme A; Magnetic Resonance Spectroscopy; Mathematics; Metals, Rare Earth; Models, Molecular; Molecular Conformation; Pantetheine; Praseodymium | 1977 |
Molecular orbital studies on the conformation of the phosphopantetheine moiety of coenzyme A.
Topics: Coenzyme A; Hydrogen Bonding; Molecular Conformation; Organophosphorus Compounds; Pantetheine; Quantum Theory; Sulfhydryl Compounds | 1977 |
Letter: Conformational studies of pantetheine and the pantetheine moiety of coenzyme A.
Topics: Coenzyme A; Magnetic Resonance Spectroscopy; Molecular Conformation; Pantetheine; Sulfhydryl Compounds | 1975 |
Separation of pigeon liver apo- and holo- fatty acid synthetases by affinity chromatography.
Topics: Adenosine Triphosphate; Animals; Apoenzymes; Chromatography, Affinity; Coenzyme A; Columbidae; Fatty Acid Synthases; Liver; Pantetheine; Rabbits | 1975 |
13C NMR or coenzyme A and its constituent moieties.
Topics: Adenosine Diphosphate; Alanine; Carbon Isotopes; Coenzyme A; Cystamine; Cysteamine; Deuterium; Disulfides; Lactones; Magnetic Resonance Spectroscopy; Mercaptoethylamines; Pantetheine; Pantothenic Acid; Protein Conformation | 1975 |
[Effects of pantethine on metabolism in myocardial mitochondria under the conditions of deep hypothermia].
Topics: Animals; Coenzyme A; Cytosol; Hypothermia; Malate Dehydrogenase; Male; Mitochondria, Heart; Oxidoreductases; Pantetheine; Rats; Rats, Inbred Strains | 1991 |
Mitochondrial synthesis of coenzyme A is on the external surface.
Topics: Adenosine Triphosphate; Animals; Atractyloside; Coenzyme A; Dinitrophenols; In Vitro Techniques; Mitochondria, Heart; Pantetheine; Rats; Uncoupling Agents | 1987 |
Two functional domains of coenzyme A activate catalysis by coenzyme A transferase. Pantetheine and adenosine 3'-phosphate 5'-diphosphate.
Topics: Acetoacetates; Adenosine Diphosphate; Animals; Coenzyme A; Coenzyme A-Transferases; Enzyme Activation; Kinetics; Myocardium; Pantetheine; Propionates; Protein Binding; Sulfhydryl Compounds; Sulfurtransferases; Swine | 1986 |
Activation and inhibition of yeast aldehyde dehydrogenase activity by pantethine and its metabolites.
Topics: Acetyl Coenzyme A; Aldehyde Dehydrogenase; Coenzyme A; Cysteamine; Enzyme Activation; Pantetheine; Pantothenic Acid; Saccharomyces cerevisiae; Sulfhydryl Compounds; Taurine | 1986 |
Hepatic CoA, S-acyl-CoA, biosynthetic precursors of the coenzyme and pantothenate-protein complexes in dietary pantothenic acid deficiency.
Topics: Acyl Coenzyme A; Animals; Body Weight; Coenzyme A; Liver; Male; Pantetheine; Pantothenic Acid; Proteins; Rats | 1987 |
Pantethine lipomodulation: evidence for cysteamine mediation in vitro and in vivo.
Topics: Animals; Cells, Cultured; Coenzyme A; Cysteamine; Diabetes Mellitus, Experimental; Humans; Hydrolysis; Hypercholesterolemia; Lipid Metabolism; Male; Pantetheine; Rabbits; Rats; Sulfhydryl Compounds | 1987 |
Adaptive synthesis of rat liver fatty acid synthetase: evidence for in vitro formation of active enzyme from inactive protein precursors and 4'-phosphopantetheine.
Topics: Animals; Carbon Radioisotopes; Coenzyme A; Dietary Fats; Enzyme Activation; Fatty Acid Synthases; Liver; Male; Organophosphorus Compounds; Pantetheine; Pantothenic Acid; Rats; Starvation; Sulfhydryl Compounds | 1974 |
Metabolism of 4'-phosphopantetheine in Escherichia coli.
Topics: Acyl Carrier Protein; Alanine; Coenzyme A; Escherichia coli; Pantetheine; Pantothenic Acid; Sulfhydryl Compounds | 1984 |
Pantethine and pantothenate effect on the CoA content of rat liver.
Topics: Animals; Coenzyme A; Cysteine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1984 |
Hydrolysis and absorption of pantothenate and its coenzymes in the rat small intestine.
Topics: Absorption; Animals; Carbon Radioisotopes; Coenzyme A; Coenzymes; Hydrolysis; Intestine, Small; Male; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains | 1983 |
[Electrocardiogram changes in the rat by coenzyme A action].
Topics: Adenosine; Animals; Coenzyme A; Cysteine; Electrocardiography; Heart; Pantetheine; Pantothenic Acid; Rats | 1984 |
Regulation of coenzyme A biosynthesis.
Topics: Acyl Carrier Protein; beta-Alanine; Coenzyme A; Escherichia coli; Organophosphorus Compounds; Pantetheine; Pantothenic Acid | 1981 |
Inactivation of 3-oxoacyl synthetase activity of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyl Coenzyme A; Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Acyltransferases; Amino Acids; Animals; Coenzyme A; Columbidae; Cysteine; Enzyme Activation; Fatty Acid Synthases; Iodoacetamide; Kinetics; Liver; Malonyl Coenzyme A; Pantetheine; Spectrophotometry | 1983 |
Role of cysteine and 4'-phosphopantetheine in the inactivation of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
Topics: Affinity Labels; Animals; Binding Sites; Coenzyme A; Columbidae; Cysteine; Fatty Acid Synthases; Kinetics; Liver; Organophosphorus Compounds; Pantetheine; Protein Binding; Sulfhydryl Compounds | 1982 |
Rat mammary-gland fatty acid synthase. A simple purification procedure and stoicheiometry of CoA ester binding.
Topics: Acyl Coenzyme A; Amino Acids; Animals; Coenzyme A; Esters; Fatty Acid Synthases; Female; Mammary Glands, Animal; Methods; NADP; Pantetheine; Pregnancy; Rats | 1982 |
Assay of the enzymatic hydrolysis of pantetheine.
Topics: Animals; Carbon Radioisotopes; Coenzyme A; Cysteamine; Hydrolysis; In Vitro Techniques; Kidney Cortex; Pantetheine; Pantothenic Acid; Substrate Specificity; Sulfhydryl Compounds; Swine | 1982 |
Studies in search of modifiers of the toxicity of mercurials and speculations on its biochemical mechanism.
Topics: Animals; Coenzyme A; Cysteine; Glutathione; Goldfish; Mercury; Methylmercury Compounds; Pantetheine | 1981 |
A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A.
Topics: 4-Butyrolactone; beta-Alanine; Coenzyme A; Cysteamine; Enzyme Precursors; Magnetic Resonance Spectroscopy; Molecular Structure; Origin of Life; Pantetheine; Solubility; Temperature | 1995 |
Pantothenic acid and its derivatives protect Ehrlich ascites tumor cells against lipid peroxidation.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Coenzyme A; Fatty Acids; Female; Ferrous Compounds; Hydrogen Peroxide; Lipid Peroxidation; Mice; Palmitic Acid; Palmitic Acids; Pantetheine; Pantothenic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
Topics: Acyl Carrier Protein; Anti-Bacterial Agents; Cloning, Molecular; Coenzyme A; DNA Primers; Escherichia coli; Molecular Structure; Multienzyme Complexes; Pantetheine; Polymerase Chain Reaction; Recombinant Proteins; Streptomyces; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) | 1997 |
The coenzyme A-synthesizing protein complex and its proposed role in CoA biosynthesis in bakers' yeast.
Topics: Catalysis; Coenzyme A; Feedback; Fungal Proteins; Molecular Weight; Multienzyme Complexes; Pantetheine; Peptide Synthases; Protein Binding; Saccharomyces cerevisiae | 1997 |
Aminoacylation of coenzyme A and pantetheine by aminoacyl-tRNA synthetases: possible link between noncoded and coded peptide synthesis.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Coenzyme A; Evolution, Molecular; Isoleucine-tRNA Ligase; Pantetheine; Peptide Biosynthesis; RNA, Transfer, Amino Acyl; Substrate Specificity | 1998 |
Selectivity of the yersiniabactin synthetase adenylation domain in the two-step process of amino acid activation and transfer to a holo-carrier protein domain.
Topics: Acylation; Adenosine Triphosphate; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Coenzyme A; Cysteine; Diphosphates; Holoenzymes; Iron-Binding Proteins; Pantetheine; Peptide Fragments; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Structure, Tertiary; Siderophores; Substrate Specificity; Thiazoles; Thiolester Hydrolases; Transfer RNA Aminoacylation; Yersinia pestis | 2000 |
The role of 4'-phosphopantetheine in t' biosynthesis of fatty acids, polyketides and peptides.
Topics: Carrier Proteins; Coenzyme A; Fatty Acids; Pantetheine; Peptides | 2000 |
Depigmenting effects of calcium D-pantetheine-S-sulfonate on human melanocytes.
Topics: Blotting, Western; Coenzyme A; Dihydroxyphenylalanine; Glycosylation; Humans; Immunoblotting; Melanins; Melanocytes; Melanoma; Membrane Glycoproteins; Monophenol Monooxygenase; Oxidoreductases; Pantetheine; Pigmentation; Proteins; Tumor Cells, Cultured | 2000 |
Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Chromatography, Gel; Coenzyme A; Cysteine; Escherichia coli; Flavin Mononucleotide; Flavoproteins; Molecular Sequence Data; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptides; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 2000 |
RNA-Catalyzed CoA, NAD, and FAD synthesis from phosphopantetheine, NMN, and FMN.
Topics: Coenzyme A; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Library; NAD; Nicotinamide Mononucleotide; Pantetheine; RNA; Sequence Analysis, RNA | 2000 |
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography, Gel; Coenzyme A; Crystallography, X-Ray; Cysteine; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Models, Chemical; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptide Synthases; Plant Proteins; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Salts; Sequence Homology, Amino Acid; Signal Transduction; Time Factors | 2001 |
Mechanistic studies on phosphopantothenoylcysteine decarboxylase.
Topics: Carboxy-Lyases; Catalysis; Coenzyme A; Cysteine; Cytidine Monophosphate; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Molecular Structure; Pantetheine; Pantothenic Acid; Peptide Synthases; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2001 |
Novel posttranslational activation of the LYS2-encoded alpha-aminoadipate reductase for biosynthesis of lysine and site-directed mutational analysis of conserved amino acid residues in the activation domain of Candida albicans.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Apoenzymes; Candida albicans; Coenzyme A; Conserved Sequence; Enzyme Activation; Holoenzymes; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Pantetheine; Protein Processing, Post-Translational | 2001 |
Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis.
Topics: Acyl Coenzyme A; Binding Sites; Binding, Competitive; Catalysis; Coenzyme A; Enzyme Stability; Hydrolases; Kinetics; Ligands; Mutagenesis, Site-Directed; Pantetheine; Substrate Specificity; Thermodynamics | 2001 |
Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site.
Topics: Adenine; Amino Acid Substitution; Aspartic Acid; Binding, Competitive; Catalysis; Coenzyme A; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Pantetheine; Phosphorus Isotopes; Protein Binding; Pseudomonas; Spectrum Analysis, Raman; Static Electricity; Substrate Specificity; Thiolester Hydrolases | 2002 |
4'-phosphopantetheine and coenzyme A biosynthesis in plants.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Arabidopsis; Biochemical Phenomena; Biochemistry; Cell Line; Cloning, Molecular; Coenzyme A; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genome, Plant; Magnesium; Models, Chemical; Molecular Sequence Data; Nucleotidyltransferases; Osmosis; Pantetheine; Plants; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Time Factors | 2003 |
Biosynthesis of coenzyme A from phospho-pantetheine and of pantetheine from pantothenate.
Topics: Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1954 |
[The growth of Lactobacillus helveticus in the presence of pantothenic acid and pantetheine, and its application to the microbiological determination of coenzyme A in tissues].
Topics: Biological Phenomena; Coenzyme A; Coenzymes; Health Services; Lactobacillus; Lactobacillus helveticus; Pantetheine; Pantothenic Acid; Physiological Phenomena | 1955 |
Enzymatic release of pantetheine from coenzyme A in animal tissues and its microbiological determination.
Topics: Animals; Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1957 |
PANTETHINE-REQUIRING BACTEROIDES.
Topics: Bacteroides; Biotin; Choline; Coenzyme A; Culture Media; Entamoeba histolytica; Folic Acid; Pantetheine; Pyridoxine; Research; Spectrophotometry; Thiamine | 1963 |
ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN.
Topics: Acyl Carrier Protein; Alkaline Phosphatase; Amines; Carbon Isotopes; Chemistry Techniques, Analytical; Chromatography; Coenzyme A; Electrophoresis; Lactobacillus; Lactones; Metabolism; Pantetheine; Pantothenic Acid; Pepsin A; Peptide Hydrolases; Phosphates; Protein Hydrolysates; Proteins; Radiometry; Research | 1965 |
The chemistry of pantothenic acid pantetheine and coenzyme A.
Topics: Coenzyme A; Coenzymes; Pantetheine; Pantothenic Acid | 1954 |
The comparative activities of pantethine, pantothenic acid, and coenzyme A for various microorganisms.
Topics: Coenzyme A; Humans; Pantetheine; Pantothenic Acid | 1951 |
In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.
Topics: Carrier Proteins; Coenzyme A; Escherichia coli; Fluorescent Dyes; Pantetheine | 2005 |
An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.
Topics: Acyl Coenzyme A; Arabidopsis; Arabidopsis Proteins; Coenzyme A; DNA, Bacterial; Fatty Acids; Molecular Sequence Data; Mutagenesis, Insertional; Pantetheine; Phenotype; RNA, Messenger; Seedlings; Seeds; Sucrose | 2006 |
Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.
Topics: Bacterial Proteins; Carrier Proteins; Coenzyme A; Escherichia coli; Kinetics; Pantetheine; Structure-Activity Relationship; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) | 2006 |
The inside tag.
Topics: Binding Sites; Coenzyme A; Escherichia coli; Fluorescent Dyes; Pantetheine; Proteins; Sequence Analysis, DNA | 2006 |
Phosphopantetheine adenylyltransferase from Escherichia coli: investigation of the kinetic mechanism and role in regulation of coenzyme A biosynthesis.
Topics: Calorimetry; Coenzyme A; Escherichia coli; Kinetics; Models, Molecular; Nucleotidyltransferases; Pantetheine; Protein Binding; Protein Conformation | 2007 |
An orthogonal purification strategy for isolating crosslinked domains of modular synthases.
Topics: Acrylates; Acyl Carrier Protein; Coenzyme A; Cross-Linking Reagents; Escherichia; Escherichia coli Proteins; Fatty Acid Synthases; Models, Molecular; Pantetheine; Polyketide Synthases; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Tertiary | 2008 |
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
Topics: Bacterial Proteins; Coenzyme A; Cysteamine; Cysteine; Genes, Bacterial; Multigene Family; Pantetheine; Streptomyces; Thienamycins | 2008 |
Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli.
Topics: Aldehyde-Lyases; Anti-Bacterial Agents; Antimetabolites; Coenzyme A; Combinatorial Chemistry Techniques; Cytochrome P-450 Enzyme System; Escherichia coli; Molecular Structure; Pantetheine; Structure-Activity Relationship | 2008 |
Solid phase 4'-phosphopantetheinylation: fungal thiolation domains are targets for chemoenzymatic modification.
Topics: Aspergillus fumigatus; Bacterial Proteins; Biocatalysis; Coenzyme A; Pantetheine; Recombinant Proteins; Transferases (Other Substituted Phosphate Groups) | 2009 |
Functional immobilization and patterning of proteins by an enzymatic transfer reaction.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Coenzyme A; Glass; Immobilized Proteins; Interferon-alpha; Models, Molecular; Oligopeptides; Pantetheine; Polyethylene Glycols; Protein Structure, Tertiary; Receptor, Interferon alpha-beta; Spectrum Analysis; Substrate Specificity; Surface Properties; Transferases (Other Substituted Phosphate Groups) | 2010 |
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Topics: Animals; Brain; Coenzyme A; Drosophila; Gene Expression Regulation; Humans; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Oxygen; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Phenotype; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis.
Topics: Adenosine Triphosphate; Calorimetry; Coenzyme A; Crystallography, X-Ray; Feedback, Physiological; Kinetics; Models, Biological; Models, Molecular; Mycobacterium tuberculosis; Nucleotidyltransferases; Pantetheine; Protein Conformation; Protein Structure, Quaternary; Recombinant Proteins; Thermodynamics | 2010 |
Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.
Topics: Adenosine Monophosphate; Amino Acid Motifs; Bacterial Proteins; Biocatalysis; Catalytic Domain; Coenzyme A; Coenzyme A Ligases; Crystallography, X-Ray; Cysteamine; Macrolides; Models, Molecular; Pantetheine; Polyketide Synthases; Pyrones; Streptomyces coelicolor; Substrate Specificity | 2011 |
Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine.
Topics: Adenosine Triphosphate; Coenzyme A; Crystallography, X-Ray; Enterococcus faecalis; Ligands; Models, Molecular; Nucleotidyltransferases; Pantetheine; Protein Structure, Quaternary | 2011 |
Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.
Topics: Acetylation; Animals; Coenzyme A; Disease Models, Animal; Drosophila; Histones; Humans; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Protein Processing, Post-Translational; Tubulin | 2011 |
Substrate recognition by β-ketoacyl-ACP synthases.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyltransferases; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Kinetics; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Palmitoyl Coenzyme A; Pantetheine; Phosphotransferases (Alcohol Group Acceptor); Substrate Specificity | 2011 |
Inhibitors of aminoglycoside resistance activated in cells.
Topics: Acetyltransferases; Aminoglycosides; Anti-Bacterial Agents; Coenzyme A; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterococcus faecium; Kanamycin; Pantetheine; Prodrugs; Structure-Activity Relationship | 2012 |
Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A.
Topics: Acyl Carrier Protein; Amino Acid Sequence; Chromatography, High Pressure Liquid; Coenzyme A; Disulfides; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glycine; Mass Spectrometry; Metabolic Networks and Pathways; Molecular Sequence Data; Pantetheine; Peptide Synthases; Phosphotransferases (Alcohol Group Acceptor); Urea | 2013 |
D-pantethine has vitamin activity equivalent to d-pantothenic acids for recovering from a deficiency of D-pantothenic acid in rats.
Topics: Acetyl Coenzyme A; Animals; Body Weight; Coenzyme A; Diet; Male; Organ Size; Pantetheine; Pantothenic Acid; Rats; Rats, Wistar; Vitamins; Weaning | 2013 |
Experimentally validated novel inhibitors of Helicobacter pylori phosphopantetheine adenylyltransferase discovered by virtual high-throughput screening.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Coenzyme A; Databases, Chemical; Drug Discovery; Enzyme Inhibitors; Helicobacter pylori; High-Throughput Screening Assays; Methotrexate; Microbial Sensitivity Tests; Molecular Docking Simulation; Nucleotidyltransferases; Pantetheine; Protein Binding | 2013 |
Integrated electroosmotic perfusion of tissue with online microfluidic analysis to track the metabolism of cystamine, pantethine, and coenzyme A.
Topics: Calibration; Coenzyme A; Cystamine; Electroosmosis; Extracellular Space; Hippocampus; Microfluidic Analytical Techniques; Pantetheine; Perfusion; Systems Integration | 2013 |
Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation.
Topics: Brain; Cloning, Molecular; Coenzyme A; Escherichia coli; Exome; Female; Fibroblasts; Gene Expression Regulation; Humans; Iron; Male; Mitochondria; Mutation, Missense; Nerve Degeneration; Pantetheine; Pedigree; Phosphorylation; Saccharomyces cerevisiae; Transferases | 2014 |
Crystal structure of phosphopantothenate synthetase from Thermococcus kodakarensis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Archaeal Proteins; Binding Sites; Coenzyme A; Crystallography, X-Ray; Multiprotein Complexes; Pantetheine; Peptide Synthases; Sequence Alignment; Thermococcus | 2014 |
Inhibitors of polyhydroxyalkanoate (PHA) synthases: synthesis, molecular docking, and implications.
Topics: Acyltransferases; Aldehydes; Animals; Bacterial Proteins; Biocatalysis; Biodegradation, Environmental; Coenzyme A; Cupriavidus necator; Dogs; Enzyme Assays; Enzyme Inhibitors; Esterases; Kinetics; Lipase; Molecular Docking Simulation; Pantetheine; Polyhydroxyalkanoates; Structural Homology, Protein; Substrate Specificity; Sulfolobus solfataricus | 2015 |
Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis.
Topics: Animals; Caenorhabditis elegans; Cell Line; Coenzyme A; Coenzyme A Ligases; Drosophila; Female; HEK293 Cells; Humans; Longevity; Male; Mice, Inbred C57BL; Pantetheine; Phosphotransferases (Alcohol Group Acceptor) | 2015 |
Metabolism: Jump-starting CoA biosynthesis.
Topics: Animals; Caenorhabditis elegans; Coenzyme A; Drosophila; Female; Humans; Male; Pantetheine | 2015 |
Coenzyme A: to make it or uptake it?
Topics: Animals; Biological Transport; Biosynthetic Pathways; Cell Membrane Permeability; Coenzyme A; Humans; Pantetheine | 2016 |
Efficient one-pot enzymatic synthesis of dephospho coenzyme A.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Chemistry Techniques, Synthetic; Cloning, Molecular; Coenzyme A; Escherichia coli; Nucleotidyltransferases; Oxidation-Reduction; Pantetheine; Phosphotransferases (Alcohol Group Acceptor); Plasmids | 2018 |
Mutations in PPCS, Encoding Phosphopantothenoylcysteine Synthetase, Cause Autosomal-Recessive Dilated Cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Biosynthetic Pathways; Cardiomyopathy, Dilated; Carnitine; Child, Preschool; Coenzyme A; Demography; Drosophila; Enzyme Stability; Female; Fibroblasts; Genes, Recessive; Heart; High-Throughput Nucleotide Sequencing; Homozygote; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Mutation; Pantetheine; Pedigree; Peptide Synthases; Reproducibility of Results; Saccharomyces cerevisiae | 2018 |
Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis.
Topics: Amino Acid Motifs; Azoles; Bacterial Proteins; Binding Sites; Carrier Proteins; Cloning, Molecular; Coenzyme A; Escherichia coli; Fluorescent Dyes; Gene Expression; Genetic Vectors; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Mycolic Acids; Nitrobenzenes; Pantetheine; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2019 |
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Topics: Animals; Biomarkers; Coenzyme A; Dopamine; Genotype; Iron; Mice; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor) | 2019 |
Design and synthesis of Coenzyme A analogues as Aurora kinase A inhibitors: An exploration of the roles of the pyrophosphate and pantetheine moieties.
Topics: Aurora Kinase A; Coenzyme A; Diphosphates; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Pantetheine; Protein Kinase Inhibitors; Structure-Activity Relationship | 2020 |
Lipoate protein ligase B primarily recognizes the C
Topics: Acyl Carrier Protein; Acyltransferases; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Ligases; Pantetheine; Thioctic Acid | 2022 |
Understanding and Circumventing the Requirement for Native Thioester Substrates for α-Oxoamine Synthase Reactions.
Topics: Acyl Carrier Protein; Coenzyme A; Kinetics; Pantetheine; Phosphates; Substrate Specificity | 2022 |