cocaine has been researched along with tyrosine in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (56.90) | 18.7374 |
| 1990's | 8 (13.79) | 18.2507 |
| 2000's | 9 (15.52) | 29.6817 |
| 2010's | 7 (12.07) | 24.3611 |
| 2020's | 1 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Lee, FL; Weiner, N | 1 |
| Bralet, J; Lallemant, AM | 2 |
| Patrick, RL; Roberts, MM | 1 |
| de Langen, CD; Mulder, AH; Stoof, JC | 1 |
| Barchas, JD; Patrick, RL | 3 |
| Barchas, JD; Patrick, RL; Snyder, TE | 1 |
| Arilla, E; Rodríguez-Sánchez, MN | 1 |
| Chadwick, MJ; Gregory, DL; Wendling, G | 1 |
| Berman, ML; Tennant, F | 1 |
| Dackis, CA; Gold, MS | 1 |
| Bagchi, SP | 1 |
| Tennant, FS | 1 |
| Lipton, MA | 1 |
| Stepanov, II | 1 |
| Angrist, B; Gershon, S | 1 |
| Stock, K; Westermann, E | 1 |
| Alousi, A; Weiner, N | 1 |
| Wennmalm, A | 1 |
| Harris, JE; Roth, RH | 1 |
| Hughes, J; Roth, RH | 1 |
| Costa, E; Groppetti, A; Naimzada, MK | 1 |
| Johnson, DG; Kopin, IJ; Thoa, NB | 1 |
| Gajda, L; Grabowska, M; Maj, J | 1 |
| Ahonen, A; Pentilä, A | 1 |
| Ando, N | 1 |
| Bhargava, KP; Kar, K; Parmar, S | 1 |
| Koppanyi, T; Maengwyn-Davies, GD | 1 |
| Haycock, DA; Patrick, RL | 1 |
| Muldoon, SM; Rorie, DK; Tyce, GM | 1 |
| Chen, SY; Kalivas, PW; Sorg, BA | 1 |
| Goeders, NE; Smith, JE | 1 |
| Chen, JG; Rudnick, G; Sachpatzidis, A | 1 |
| Dohi, T; Kitayama, S; Mitsuhata, C; Morita, K; Uhl, GR; Vandenbergh, D | 1 |
| Hirsh, J; McClung, C | 1 |
| Farmer, JA; Frangogiannis, NG; Lakkis, NM | 1 |
| Cowen, PJ; McTavish, SF; Raumann, B; Sharp, T | 1 |
| Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Brimijoin, S; Lockridge, O; Pang, YP; Sun, H | 1 |
| Barbas, CF; Basran, A; Bruce, NC; Larsen, NA; Lerner, RA; Turner, JM; Wilson, IA | 1 |
| LUDDEN, CT; PORTER, CC; STAVORSKI, JM; STONE, CA; TOTARO, JA | 1 |
| HURKMANS, AT | 1 |
| SIGG, EB; SIGG, TD | 1 |
| Gether, U; Grånäs, C; Javitch, JA; Loland, CJ | 1 |
| Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF | 1 |
| Benkelfat, C; Casey, KF; Delaney, JS; Kolivakis, T; Leyton, M | 1 |
| Michaeli, A; Schumann, J; Yaka, R | 1 |
| Benkelfat, C; Casey, KF; Cox, SM; Dagher, A; Delaney, JS; Durand, F; Kolivakis, T; Leyton, M; McKenzie, SA | 1 |
| Besnard, A; Caboche, J; Girault, JA; Heck, N; Hervé, D; Pagès, C; Pascoli, V; Vanhoutte, P | 1 |
| Gramage, E; Herradón, G; Pérez-García, C; Vicente-Rodríguez, M | 1 |
| Huang, X; Midde, NM; Quizon, PM; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J | 1 |
| Bagdas, D; Carroll, FI; Damaj, MI; Greenwald, M; Jackson, A; Lichtman, AH; Miles, MF; Muldoon, PP | 1 |
| Abbott, T; Eipper, BA; Kiraly, DD; Koleske, AJ; Lam, TT; Levy, AD; Machida, K; Mains, RE; Miller, MB; Wu, YI; Yan, Y | 1 |
| Brietzke, E; Carvalho, MSC; Costa, TBBC; Hayashi, MAF; Lacerda, ALT; Marins, LAN; Martins, LG; Mas, CD; Mitrovitch, MP; Nunes, MV; Pedrini, M; Pontes, JGM; Poppi, RJ; Saldanha, NL; Tasic, L | 1 |
| Ambrosio, E; Anadón, A; Capellán, R; Crego, AL; Higuera-Matas, A; Marcos, A; Martínez-Larrañaga, MR; Moreno, M; Mª de Paz, A; Orihuel, J; Ucha, M | 1 |
2 review(s) available for cocaine and tyrosine
| Article | Year |
|---|---|
Pharmacological approaches to cocaine addiction.
Topics: Brain Chemistry; Bromocriptine; Cocaine; Desipramine; Dopamine; Euphoria; Humans; Receptors, Dopamine; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders; Tyrosine | 1985 |
Dopamine and psychotic states: preliminary remarks.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Carbon Radioisotopes; Cats; Cocaine; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Methylphenidate; Pemoline; Phenmetrazine; Pimozide; Psychoses, Substance-Induced; Psychotic Disorders; Rats; Receptors, Cell Surface; Species Specificity; Stereotyped Behavior; Thioridazine; Tyrosine | 1974 |
3 trial(s) available for cocaine and tyrosine
| Article | Year |
|---|---|
A double-blind amino acids, L-tryptophan and L-tyrosine, and placebo study with cocaine-dependent subjects in an inpatient chemical dependency treatment center.
Topics: Adolescent; Adult; Cocaine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; MMPI; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1990 |
Cocaine craving, euphoria, and self-administration: a preliminary study of the effect of catecholamine precursor depletion.
Topics: Adult; Catecholamines; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Diet, Protein-Restricted; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Humans; Levodopa; Male; Phenylalanine; Self Administration; Time Factors; Tyrosine | 2005 |
Striatal dopamine responses to intranasal cocaine self-administration in humans.
Topics: Administration, Intranasal; Basal Ganglia; Cocaine; Dopamine; Female; Humans; Hydrocortisone; Male; Phenylalanine; Positron-Emission Tomography; Putamen; Raclopride; Receptors, Dopamine D2; Self Administration; Tyrosine; Young Adult | 2009 |
53 other study(ies) available for cocaine and tyrosine
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Norepinephrine release and the activation of tyrosine hydroxylase during nerve stimulation.
Topics: Animals; Cocaine; Corpus Striatum; Corticosterone; Cyclic AMP; Electric Stimulation; Enzyme Activation; In Vitro Techniques; Male; Norepinephrine; Rats; Stimulation, Chemical; Tyrosine; Tyrosine 3-Monooxygenase; Vas Deferens | 1976 |
[The effect of cocaine treatment on the level of dopamine and serotonin regeneration and on the level of acetylcholine in rat brain].
Topics: Acetylcholine; Animals; Brain; Cocaine; Dopamine; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Probenecid; Rats; Serotonin; Tyrosine | 1976 |
Amphetamine- and phenylethylamine-induced alterations in dopamine synthesis regulation in rat brain striatal synaptosomes.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; In Vitro Techniques; Male; Phenethylamines; Rats; Synaptosomes; Tyrosine; Veratridine | 1979 |
Studies on the nature of the releasable pool of dopamine in synaptosomes from rat corpus striatum: depolarization-induced release of 3H-dopamine from superfused synaptosomes labelled under various conditions.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Rats; Synaptosomes; Time Factors; Tyramine; Tyrosine | 1979 |
Potentiation by cocaine of the stimulus-induced increase in dopamine synthesis in rat brain striatal synaptosomes.
Topics: Animals; Benztropine; Brain; Cocaine; Dopamine; Drug Synergism; In Vitro Techniques; Male; Rats; Tyrosine; Veratridine; Veratrine | 1977 |
Regulation of dopamine synthesis in rat brain striatal synaptosomes.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Male; Rats; Strontium; Synaptosomes; Time Factors; Tyrosine; Veratridine | 1975 |
[The influence of treatment with cocaine on the synthesis and liberation of cerebral noradrenaline].
Topics: Animals; Brain; Brain Chemistry; Cocaine; Male; Methyltyrosines; Norepinephrine; Rats; Tranylcypromine; Tyrosine | 1975 |
Dopamine synthesis in rat brain striatal synaptosomes. I. Correlations between veratridine-induced synthesis stimulation and endogenous dopamine release.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Pargyline; Rats; Stimulation, Chemical; Synaptosomes; Tetrodotoxin; Time Factors; Tyrosine; Veratridine; Veratrine | 1976 |
Somatostatin receptors increase in the olfactory bulb of developing pups after perinatal exposure to cocaine.
Topics: Animals; Animals, Newborn; Cocaine; Female; Olfactory Bulb; Osmolar Concentration; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Somatostatin; Reference Values; Somatostatin; Time Factors; Tyrosine | 1992 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1988 |
Cocaine and phencyclidine. Heterogenous dopaminergic interactions with tetrabenazine.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Drug Interactions; In Vitro Techniques; Mitochondria; Nalidixic Acid; Naphthyridines; Phencyclidine; Phenylalanine; Rats; Receptors, Dopamine; Reserpine; Synaptosomes; Tetrabenazine; Tyrosine | 1985 |
Effect of cocaine dependence on plasma phenylalanine and tyrosine levels and on urinary MHPG excretion.
Topics: Adult; Cocaine; Female; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Phenylalanine; Substance-Related Disorders; Tyrosine | 1985 |
Regulation of catecholamine synthesis in rat brain synaptosomes.
Topics: Animals; Brain; Brain Stem; Catecholamines; Cerebral Cortex; Chromatography, Ion Exchange; Cocaine; Corpus Striatum; Dopamine; Kinetics; Male; Norepinephrine; Potassium; Rats; Reserpine; Serotonin; Synaptosomes; Time Factors; Tritium; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
Neuropsychopharmacology of monoamines and their regulatory enzymes.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Biogenic Amines; Brain; Cocaine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dopamine beta-Hydroxylase; Humans; Isoenzymes; Methylphenidate; Monoamine Oxidase; Neurons; Norepinephrine; Phenylethanolamine N-Methyltransferase; Schizophrenia; Serotonin; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
[On the importance of mediator sources in the terminal parts of noradrenergic neurons for synaptic transmission of impulses to smooth muscle].
Topics: Animals; Cocaine; Dogs; Male; Muscle Contraction; Norepinephrine; Penis; Sympathetic Nervous System; Synaptic Transmission; Time Factors; Tyrosine | 1969 |
[On the significance of the noradrenaline content of fatty tissue for the mobilization of unesterified fatty acids].
Topics: Adipose Tissue; Adrenal Medulla; Animals; Cocaine; Cold Temperature; Enzymes; Epididymis; Epinephrine; Fatty Acids; In Vitro Techniques; Lipids; Male; Metaraminol; Methyldopa; Methyltyrosines; Nialamide; Norepinephrine; Normetanephrine; Octopamine; Pargyline; Rats; Reserpine; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase | 1965 |
The regulation of norepinephrine synthesis in sympathetic nerves: effect of nerve stimulation, cocaine, and catecholamine-releasing agents.
Topics: Animals; Cocaine; Electric Stimulation; Guinea Pigs; Hydrazines; In Vitro Techniques; Norepinephrine; Reserpine; Sympathetic Nervous System; Tritium; Tyramine; Tyrosine | 1966 |
Studies on mechanisms controlling the secretion of neurotransmitters in the rabbit heart.
Topics: Acetylcholine; Animals; Carbon Isotopes; Catecholamines; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Cocaine; Depression, Chemical; Desipramine; Electric Stimulation; Ergotamine; Female; Ganglionic Blockers; Heart; Hexamethonium Compounds; Hydrogen-Ion Concentration; Male; Myocardium; Nerve Endings; Norepinephrine; Perfusion; Propylamines; Prostaglandins; Rabbits; Spectrophotometry; Stimulation, Chemical; Synaptic Transmission; Time Factors; Tritium; Tyrosine | 1971 |
Potassium-induced acceleration of catecholamine biosynthesis in brain slices. I. A study of the mechanism of action.
Topics: Animals; Brain; Calcium; Carbon Isotopes; Catecholamines; Cocaine; Corpus Striatum; Dopamine; Kinetics; Magnesium; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Tyrosine; Tyrosine 3-Monooxygenase | 1971 |
Variation in noradrenaline output with changes in stimulus frequency and train length: role of different noradrenaline pools.
Topics: Animals; Carbon Radioisotopes; Chromatography; Cocaine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Norepinephrine; Phenoxybenzamine; Portal Vein; Rabbits; Stimulation, Chemical; Tyrosine; Vas Deferens | 1974 |
Effects of amphetamine on the turnover rate of brain catecholamines and motor activity.
Topics: Animals; Appetite; Body Temperature Regulation; Brain; Cocaine; Corpus Striatum; Dextroamphetamine; Diencephalon; Dopamine; Feeding and Eating Disorders; Feeding Behavior; Fever; Humans; Male; Motor Activity; Norepinephrine; Rats; Telencephalon; Tritium; Tyrosine | 1972 |
Inhibition of norepinephrine biosynthesis by chlorpromazine in the guinea-pig vas deferens.
Topics: Animals; Carbon Isotopes; Chlorpromazine; Cocaine; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Electric Stimulation; Guinea Pigs; Hypogastric Plexus; In Vitro Techniques; Male; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Octopamine; Tritium; Tyrosine; Vas Deferens | 1971 |
Effect of apomorphine on motility in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Benzyl Compounds; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Esters; Fluorine; Haloperidol; Hydrazines; Male; Motor Activity; Nialamide; Nortriptyline; Phenoxybenzamine; Rats; Rats, Inbred Strains; Reserpine; Serine; Spiro Compounds; Stimulation, Chemical; Thiocarbamates; Tranquilizing Agents; Tyrosine | 1972 |
Effect of some drugs on the uptake of monoamines and their precursors in the mouse Paneth cells.
Topics: 5-Hydroxytryptophan; Amines; Amitriptyline; Amphetamine; Animals; Binding Sites; Catecholamines; Chlorpromazine; Cocaine; Colon; Cytoplasmic Granules; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Duodenum; Female; Guanethidine; Ileum; Imipramine; Jejunum; Male; Methyltyrosines; Mice; Microscopy, Fluorescence; Nortriptyline; Pargyline; Peptide Biosynthesis; Promazine; Reserpine; Serotonin; Tyrosine | 1971 |
[Release and biosynthesis of noradrenaline in the organs controlled by the nervous system].
Topics: Acetylcholine; Animals; Bretylium Compounds; Calcium; Carbon Isotopes; Cocaine; Dihydroxyphenylalanine; Dopamine; Guanethidine; Guanidines; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine; Potassium; Sodium; Sympathetic Nervous System; Tyrosine; Vas Deferens | 1970 |
Mechanism of action of dopamine and other precursors of noradrenaline on the guinea-pig isolated hypogastric nerve vas deferens preparation.
Topics: Animals; Cocaine; Dihydroxyphenylalanine; Disulfiram; Dopamine; Guinea Pigs; Hypogastric Plexus; Male; Norepinephrine; Phenoxybenzamine; Reserpine; Tyramine; Tyrosine; Vas Deferens | 1968 |
Cocaine tachyphylaxis and effects on indirectly-acting sympathomimetic drugs in the rabbit aortic strip and in splenic tissue.
Topics: Amphetamine; Animals; Aorta; Cocaine; Dextroamphetamine; Disulfiram; Enzymes; In Vitro Techniques; Iproniazid; Methyltyrosines; Nialamide; Norepinephrine; Pargyline; Phenylephrine; Rabbits; Spleen; Tachyphylaxis; Tranylcypromine; Tyramine; Tyrosine | 1966 |
Catecholamine synthesis regulation in hypothalamic synaptosomes.
Topics: Animals; Bucladesine; Catecholamines; Cocaine; Corpus Striatum; Desipramine; Dextroamphetamine; Dopamine; Hypothalamus; Male; Norepinephrine; Potassium; Rats; Synaptosomes; Tyrosine | 1981 |
Effects of L-dopa and L-tyrosine on adrenergic transmission in the canine saphenous vein.
Topics: Animals; Blood Vessels; Calcium; Cocaine; Corticosterone; Dogs; Dopamine; In Vitro Techniques; Levodopa; Norepinephrine; Saphenous Vein; Sympathetic Nervous System; Synaptic Transmission; Tyrosine; Vasoconstriction | 1982 |
Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Drug Tolerance; Hydroxylation; Male; Mesencephalon; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 1993 |
Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred F344; Self Administration; Tyrosine | 1993 |
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding.
Topics: Asparagine; Binding Sites; Carrier Proteins; Cell Line; Cell Membrane; Cocaine; Cysteine; Ethyl Methanesulfonate; Humans; Indicators and Reagents; Isoleucine; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tyrosine | 1997 |
Tyrosine-533 of rat dopamine transporter: involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine.
Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Sequence; Animals; Carrier Proteins; Cocaine; COS Cells; Cricetinae; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Rats; Substrate Specificity; Tyrosine | 1998 |
The trace amine tyramine is essential for sensitization to cocaine in Drosophila.
Topics: Animals; Brain; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drosophila melanogaster; Male; Mixed Function Oxygenases; Mutation; Octopamine; Time Factors; Tyramine; Tyrosine; Tyrosine Decarboxylase | 1999 |
Tirofiban for cocaine-induced coronary artery thrombosis: a novel therapeutic approach.
Topics: Adult; Cocaine; Coronary Thrombosis; Fibrinolytic Agents; Humans; Male; Tirofiban; Tyrosine; Vasoconstrictor Agents | 1999 |
Tyrosine depletion attenuates the behavioural stimulant effects of amphetamine and cocaine in rats.
Topics: Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology.
Topics: Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Cocaine; Codon; COS Cells; Desipramine; Dopamine; Fluoxetine; Humans; Kinetics; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Structure-Activity Relationship; Symporters; Transfection; Tyrosine | 2001 |
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Topics: Alanine; Amino Acid Substitution; Animals; Butyrylcholinesterase; CHO Cells; Cocaine; Cricetinae; Genetic Engineering; Hydrolases; Models, Molecular; Tryptophan; Tyrosine | 2002 |
Biochemical characterization and structural analysis of a highly proficient cocaine esterase.
Topics: Bacterial Proteins; Binding Sites; Binding Sites, Antibody; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Cocaine; Crystallization; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrolysis; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Rhodococcus; Structure-Activity Relationship; Substrate Specificity; Tyrosine; Urea | 2002 |
ANTAGONISM OF CERTAIN EFFECTS OF CATECHOLAMINE-DEPLETING AGENTS BY ANTIDEPRESSANT AND RELATED DRUGS.
Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Catecholamines; Chlorpromazine; Cocaine; Desipramine; Dogs; Dopamine; Electric Stimulation; Electrophysiology; Guanethidine; Imipramine; Metaraminol; Methylphenidate; Mice; Myocardium; Nictitating Membrane; Norepinephrine; Pharmacology; Piperidines; Promazine; Research; Reserpine; Tripelennamine; Tyrosine | 1964 |
MECHANISM OF ACTION OF PSYCHOMOTOR STIMULANT DRUGS. SIGNIFICANCE OF DOPAMINE IN LOCOMOTOR STIMULANT ACTION.
Topics: Amino Acids; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dopamine; Mice; Movement; Pargyline; Pharmacology; Research; Reserpine; Sympatholytics; Tyrosine | 1964 |
SYMPATHEIC STIMULATION AND BLOCKADE OF THE URINARY BLADDER IN CAT.
Topics: Acetylcholine; Atropine; Bretylium Compounds; Cats; Choline; Cocaine; Dopamine; Electric Stimulation; Ergotamine; Guanethidine; Hexamethonium Compounds; Hypogastric Plexus; Imipramine; Methyltyrosines; Norepinephrine; Pharmacology; Phentolamine; Physostigmine; Research; Reserpine; Serotonin; Sympathetic Nervous System; Tyramine; Tyrosine; Urinary Bladder | 1964 |
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.
Topics: Alanine; Amino Acid Sequence; Animals; Biotinylation; Blotting, Western; Cell Membrane; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Norepinephrine; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Transfection; Tyrosine; Zinc | 2004 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Src-protein tyrosine kinases are required for cocaine-induced increase in the expression and function of the NMDA receptor in the ventral tegmental area.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Electrophysiology; Excitatory Postsynaptic Potentials; Indicators and Reagents; Long-Term Potentiation; Male; Patch-Clamp Techniques; Phosphorylation; Proto-Oncogene Proteins c-fyn; Rats; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Subcellular Fractions; Tyrosine; Ventral Tegmental Area | 2009 |
Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.
Topics: Animals; Calcium; Cocaine; Conditioning, Psychological; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Mice; Motor Activity; Neurons; Phenols; Phosphorylation; Piperidines; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Tyrosine | 2011 |
Phosphoproteomic analysis of the striatum from pleiotrophin knockout and midkine knockout mice treated with cocaine reveals regulation of oxidative stress-related proteins potentially underlying cocaine-induced neurotoxicity and neurodegeneration.
Topics: Animals; Blotting, Western; Carrier Proteins; Chromatography, Affinity; Cocaine; Cytokines; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Knockout; Midkine; Neostriatum; Neurodegenerative Diseases; Neurotoxicity Syndromes; Oxidative Stress; Phosphoproteins; Phosphorylation; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2013 |
Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport.
Topics: Animals; Binding Sites; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Lysine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Conformation; tat Gene Products, Human Immunodeficiency Virus; Tyrosine | 2015 |
In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Benzamides; Bridged Bicyclo Compounds; Cocaine; Conditioning, Operant; Disease Models, Animal; Fenofibrate; Hypolipidemic Agents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Oxazoles; PPAR alpha; Pyrimidines; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tyrosine | 2017 |
Brain Region and Isoform-Specific Phosphorylation Alters Kalirin SH2 Domain Interaction Sites and Calpain Sensitivity.
Topics: Animals; Binding Sites; Calpain; Cocaine; Dopamine Uptake Inhibitors; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Male; Mass Spectrometry; Nucleus Accumbens; PDZ Domains; Phosphorylation; Prefrontal Cortex; Protein Isoforms; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; src Homology Domains; Tyrosine | 2017 |
Insights into the Effects of Crack Abuse on the Human Metabolome Using a NMR Approach.
Topics: Blood Specimen Collection; Carnitine; Case-Control Studies; Cocaine-Related Disorders; Crack Cocaine; Histidine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolome; Tyrosine | 2019 |
The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats.
Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Ethanol; Female; Humans; Infusions, Intravenous; Male; Rats; Reinforcement, Psychology; Self Administration; Sex Factors; Substance-Related Disorders; Tyrosine | 2020 |