cocaine and troparil

cocaine has been researched along with troparil in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's15 (60.00)18.2507
2000's4 (16.00)29.6817
2010's0 (0.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Brownell, AL; Brownell, GL; Davenport, PD; Elmaleh, DR; Hantraye, P; Isacson, O; Madras, BK; Maziere, M; Riche, D; Schumacher, JM1
Carroll, FI; De Costa, BR; Grieg, N; Kim, A; Pert, A; Rice, KC; Rothman, RB1
Abraham, P; Boja, JW; Carroll, FI; Gao, Y; Kuhar, MJ; Lew, R; Lewin, AH; Patel, A1
Balster, RL; Carroll, FI; Graham, JH; Lewin, AH; Mansbach, RS; Philip, A; Rahman, MA; Showalter, VM1
Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Philip, A; Rahman, MA2
Boja, JW; Carroll, FI; Grigoriadis, D; Kuhar, MJ; Lewis, AH; Ritz, MC; Zaczek, R1
Boja, JW; Kuhar, MJ; Scheffel, U1
Reith, ME1
Lajtha, A; Reith, ME; Sershen, H1
Goldberg, SR; Kelleher, RT; Spealman, RD1
Järbe, TU1
Abraham, P; Boja, JW; Carroll, FI; Gao, Y; Kuhar, MJ; Kuzemko, MA; Lewin, AH; Mascarella, SW1
Boja, JW; Brouard, A; Carroll, FI; Kuhar, MJ; Pelaprat, D; Rostene, W; Vial, M1
Marburger, A; Morgenstern, R; Reum, T; Schäfer, U; Schönfuss, D1
Aronson, B; Enmon, JL; Izenwasser, S; Katz, JL; Kelkar, SV; Luo, L; Nolan, SP; Trudell, ML1
Abraham, P; Boja, JW; Carroll, FI; Kotian, P; Kuhar, MJ; Lewin, AH; Mascarella, SW1
Abraham, P; Burgess, JP; Carroll, FI; Chang, AC; Kuhar, MJ; Mascarella, SW1
Izenwasser, S; Katz, JL; Klein, CL; Lomenzo, SA; Terry, PD; Trudell, ML; Zhu, N1
Steketee, JD1
Alagille, D; Baldessarini, RJ; Baldwin, RM; Fu, X; Innis, RB; Kula, NS; Tamagnan, G1
Cooper, ZD; Jutkiewicz, EM; Landry, DW; Larsen, NA; Mierzejewski, P; Narasimhan, D; Sunahara, RK; Wilson, IA; Woods, JH1
Baladi, MG; Cooper, ZD; Jutkiewicz, EM; Narasimhan, D; Sunahara, RK; Woods, JH1
Carroll, FI; Jin, C; Navarro, HA1
Bednarek, E; Błażewicz, A; Naumczuk, B; Popławska, M1

Other Studies

25 other study(ies) available for cocaine and troparil

ArticleYear
A primate model of Huntington's disease: functional neural transplantation and CT-guided stereotactic procedures.
    Cell transplantation, 1992, Volume: 1, Issue:4

    Topics: Animals; Apomorphine; Brain Tissue Transplantation; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Deoxyglucose; Female; Fetal Tissue Transplantation; Fluorodeoxyglucose F18; Glucose; Graft Survival; Huntington Disease; Ibotenic Acid; Male; Motor Activity; Neurotoxins; Papio; Putamen; Quinolinic Acid; Rats; Stereotaxic Techniques; Tomography, Emission-Computed; Tomography, X-Ray Computed; Transplantation, Heterologous

1992
Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Nomifensine; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior

1992
Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.
    Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10

    Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, Drug

1992
Potent substituted-3 beta-phenyltropane analogs of cocaine have cocaine-like discriminative stimulus effects.
    Drug and alcohol dependence, 1991, Dec-31, Volume: 29, Issue:2

    Topics: Animals; Appetitive Behavior; Association Learning; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Rats; Receptors, Dopamine; Structure-Activity Relationship

1991
Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.
    Molecular pharmacology, 1991, Volume: 39, Issue:3

    Topics: Animals; Benzamides; Binding, Competitive; Brain Stem; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Thiocyanates

1991
New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
    European journal of pharmacology, 1990, Aug-10, Volume: 184, Issue:2-3

    Topics: Animals; Binding, Competitive; Biological Transport; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Radioligand Assay; Rats; Synaptosomes

1990
[3H]WIN 35,065-2: a ligand for cocaine receptors in striatum.
    Journal of neurochemistry, 1990, Volume: 55, Issue:5

    Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Hydroxydopamines; Ligands; Male; Oxidopamine; Rats; Receptors, Drug; Tritium

1990
Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.
    Synapse (New York, N.Y.), 1989, Volume: 4, Issue:4

    Topics: Animals; Carrier Proteins; Cocaine; Male; Mice; Receptors, Drug

1989
Effect of repeated administration of various doses of cocaine and WIN 35,065-2 on locomotor behavior of mice.
    European journal of pharmacology, 1986, Oct-14, Volume: 130, Issue:1-2

    Topics: Anesthetics, Local; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Mice, Inbred BALB C; Motor Activity

1986
Saturable (3H)cocaine binding in central nervous system of mouse.
    Life sciences, 1980, Sep-22, Volume: 27, Issue:12

    Topics: Animals; Brain; Cell Membrane; Cocaine; Male; Mice; Morphine; Naloxone; Neurotransmitter Agents; Nicotine; Tubocurarine

1980
Stereoselective behavioral effects of cocaine and a phenyltropane analog.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 225, Issue:3

    Topics: Animals; Cocaine; Electroshock; Feeding Behavior; Male; Reinforcement Schedule; Saimiri; Stereoisomerism; Structure-Activity Relationship

1983
Cocaine cue in pigeons: time course studies and generalization to structurally related compounds (norcocaine, WIN 35,428 and 35,065-2) and (+)-amphetamine.
    British journal of pharmacology, 1981, Volume: 73, Issue:4

    Topics: Animals; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Structure-Activity Relationship; Time Factors

1981
Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
    Journal of medicinal chemistry, 1994, Sep-02, Volume: 37, Issue:18

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Chemical; Models, Molecular; Molecular Conformation; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1994
Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
    Brain research. Developmental brain research, 1993, Sep-17, Volume: 75, Issue:1

    Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Dopamine; Embryo, Mammalian; Fluoxetine; Iodine Radioisotopes; Kinetics; Mesencephalon; Neurons; Nomifensine; Rats; Rats, Wistar; Stereoisomerism; Tritium

1993
Grafts modulate dopamine transporters of the non-lesioned striatum.
    Neuroreport, 1995, Oct-02, Volume: 6, Issue:14

    Topics: Analysis of Variance; Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fetal Tissue Transplantation; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Rats; Rats, Wistar; Reference Values; Synaptosomes

1995
Synthesis and ligand binding of eta(6)-(2beta-carbomethoxy-3beta-phenyltropane) transition metal complexes.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Organometallic Compounds; Putamen; Rats; Structure-Activity Relationship; Tropanes

1996
Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.
    Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14

    Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Rats; Structure-Activity Relationship

1996
Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.
    Journal of medicinal chemistry, 1997, Apr-11, Volume: 40, Issue:8

    Topics: Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters

1997
Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Rats; Tropanes

1997
Repeated injection of GBR 12909, but not cocaine or WIN 35,065-2, into the ventral tegmental area induces behavioral sensitization.
    Behavioural brain research, 1998, Volume: 97, Issue:1-2

    Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Injections; Male; Microdialysis; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area

1998
Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes.
    Bioorganic & medicinal chemistry letters, 2006, Jan-01, Volume: 16, Issue:1

    Topics: Animals; Cell Membrane; Chemistry, Pharmaceutical; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Design; Humans; Kinetics; Models, Chemical; Prosencephalon; Protein Binding; Protein Transport; Rats; Serotonin Plasma Membrane Transport Proteins

2006
Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.
    Molecular pharmacology, 2006, Volume: 70, Issue:6

    Topics: Animals; Bacteria; Butyrylcholinesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cocaine; Humans; Hydrolysis; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization

2006
A bacterial cocaine esterase protects against cocaine-induced epileptogenic activity and lethality.
    Annals of emergency medicine, 2009, Volume: 54, Issue:3

    Topics: Animals; Anticonvulsants; Bacteria; Carboxylic Ester Hydrolases; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Electroencephalography; Hypnotics and Sedatives; Male; Midazolam; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome

2009
Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter.
    Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24

    Topics: Chemistry, Pharmaceutical; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Temperature; Tropanes

2008
Identification and structural characterization of three psychoactive substances, phenylpiperazines (pBPP and 3,4-CFPP) and a cocaine analogue (troparil), in collected samples.
    Forensic toxicology, 2022, Volume: 40, Issue:1

    Topics: Central Nervous System Agents; Cocaine; Gas Chromatography-Mass Spectrometry; Piperazines

2022