Compounds > cocaine

cocaine and sr141716

cocaine has been researched along with sr141716 in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (6.25)18.2507
2000's27 (56.25)29.6817
2010's16 (33.33)24.3611
2020's2 (4.17)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chaperon, F; Puech, AJ; Soubrié, P; Thiébot, MH1
Akinshola, BE; Chakrabarti, A; Onaivi, ES1
Goldberg, SR; Munzar, P; Tanda, G1
Cossu, G; Fattore, L; Fratta, W; Martellotta, MC; Mascia, MS1
Piomelli, D1
Crombag, H; De Vries, TJ; Dieben, J; Homberg, JR; Schoffelmeer, AN; Schuurman, K; Shaham, Y; Vanderschuren, LJ1
Deroche-Gamonet, V; Le Moal, M; Piazza, PV; Soubrié, P1
Balster, RL; Beardsley, PM; Dance, ME; Munzar, P1
Nomikos, GG; Panagis, G; Vlachou, S1
Forman, LJ1
France, CP; McMahon, LR1
Burton, P; Mechoulam, R; Parker, LA; Sorge, RE; Yakiwchuk, C1
Gessa, GL; Melis, M; Muntoni, AL; Perra, S; Pillolla, G; Pistis, M1
Cossu, G; Deiana, S; Fadda, P; Fattore, L; Fratta, W; Spano, MS1
Burbach, JP; Gerrits, MA; Hoogveld, E; Lesscher, HM; van Ree, JM1
Ledent, C; Maldonado, R; Mendizábal, V; Parmentier, M; Robledo, P; Soria, G; Touriño, C; Valverde, O1
Goldberg, SR; Justinova, Z; Redhi, GH; Solinas, M; Tanda, G1
Filip, M; Frankowska, M; Göthert, M; Przegaliński, E1
Caillé, S; Parsons, LH1
Battista, N; Bernardi, G; Centonze, D; De Chiara, V; Maccarrone, M; Mercuri, NB; Prosperetti, C; Rossi, S; Usiello, A1
Constales, C; Miller, DK; Putnam, WC; Rodvelt, KR1
Dillon, C; Gardner, EL; Gilbert, J; Li, X; Pak, AC; Peng, XQ; Spiller, K; Xi, ZX1
French, ED; Gerdeman, GL; Schechter, JB1
Nomikos, GG; Panagis, G; Stamatopoulou, F; Vlachou, S1
De Vries, TJ; Pattij, T; Schoffelmeer, AN; Wiskerke, J1
Gardner, EL; Hoffman, AF; Li, X; Lupica, CR; Peng, XQ; Xi, ZX1
Edwards, S; George, O; Koob, GF; Orio, L; Parsons, LH1
Dykstra, LA; Rosenberg, M; Walker, EA; Ward, SJ1
Walker, EA; Ward, SJ1
Fernandez-Espejo, E; Moratalla, R; Ortiz, O; Ramiro-Fuentes, S1
Jiang, W; Liu, JF; Lu, L; Wang, XY; Xue, YX; Yu, LL; Zhou, SJ1
Castelli, MP; Ennas, MG; Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M1
Fernandez-Espejo, E; Ramiro-Fuentes, S1
Lecca, S; Luchicchi, A; Melis, M; Muntoni, AL; Pistis, M1
Carroll, FI; McMahon, LR; Schulze, DR1
Chorvat, RJ1
Chun, LE; Green, JL; Katz, JL; Mereu, M; Tanda, G; Thomas, AM; Tronci, V1
Abbas, Z; Arvanitogiannis, A; Bernstein, DL; Cheer, JF; Gentry, RN; Hernandez, G; Oleson, EB1
Hu, SS; Liu, YW; Yu, L1
Baldaia, MA; Berro, LF; Frussa-Filho, R; Hollais, AW; Longo, BM; Marinho, EA; Oliveira-Lima, AJ; Patti, CL; Santos, R; Takatsu-Coleman, AL; Wuo-Silva, R; Yokoyama, TS1
Goldberg, SR; Justinova, Z; Makriyannis, A; Redhi, GH; Scherma, M; Schindler, CW; Vadivel, SK1
Antoniou, K; Delis, F; Goldberg, SR; Justinova, Z; Nomikos, GG; Polissidis, A; Poulia, N1
Baldaia, MA; Berro, LF; da Silva, RW; Frussa-Filho, R; Hollais, AW; Longo, BM; Marinho, EAV; Oliveira-Lima, AJ; Ribeiro, LTC; Santos-Baldaia, R; Talhati, F; Yokoyama, TS1
Hearing, MC; Huffington, ED; Ingebretson, AE; Thomas, MJ1
Ayvazian, VM; Beebe, EJ; Cheer, JF; Cruz, FC; Engi, SA; Wenzel, JM; Zlebnik, NE1
Chang, HA; Dai, W; Hu, SS1
Elvert, R; Haschke, G; Herling, AW; Kilp, S; Kramer, W1

Reviews

2 review(s) available for cocaine and sr141716

ArticleYear
The role of CB1 receptors in psychostimulant addiction.
    Addiction biology, 2008, Volume: 13, Issue:2

    Topics: Amphetamine-Related Disorders; Amphetamines; Animals; Association Learning; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Humans; Mice; Motivation; Neuronal Plasticity; Neurotransmitter Agents; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Substance-Related Disorders

2008
Peripherally restricted CB1 receptor blockers.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Animals; Brain; Cocaine; Drug Discovery; Humans; Liver Diseases; Metabolic Diseases; Morpholines; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Sulfonamides

2013

Other Studies

46 other study(ies) available for cocaine and sr141716

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats.
    Psychopharmacology, 1998, Volume: 135, Issue:4

    Topics: Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Morpholines; Motor Activity; Naphthalenes; Narcotics; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

1998
In-vitro and in-vivo action of cannabinoids.
    Neurochemical research, 1999, Volume: 24, Issue:10

    Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cyclic AMP; Gene Expression; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Piperidines; Polymerase Chain Reaction; Pyrazoles; Receptors, AMPA; Recombinant Proteins; Rimonabant; Xenopus laevis

1999
Self-administration behavior is maintained by the psychoactive ingredient of marijuana in squirrel monkeys.
    Nature neuroscience, 2000, Volume: 3, Issue:11

    Topics: Animals; Behavior, Animal; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dronabinol; Marijuana Smoking; Piperidines; Psychotropic Drugs; Pyrazoles; Reinforcement, Psychology; Rimonabant; Saimiri; Self Administration

2000
CB1 cannabinoid receptor agonist WIN 55,212-2 decreases intravenous cocaine self-administration in rats.
    Behavioural brain research, 1999, Volume: 104, Issue:1-2

    Topics: Animals; Benzoxazines; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Injections, Intravenous; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Self Administration

1999
Cannabinoid activity curtails cocaine craving.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2001
A cannabinoid mechanism in relapse to cocaine seeking.
    Nature medicine, 2001, Volume: 7, Issue:10

    Topics: Animals; Behavior, Animal; Cannabinoid Receptor Modulators; Cannabinoids; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dronabinol; Humans; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Recurrence; Rimonabant

2001
SR141716, a CB1 receptor antagonist, decreases the sensitivity to the reinforcing effects of electrical brain stimulation in rats.
    Psychopharmacology, 2001, Volume: 157, Issue:3

    Topics: Animals; Brain; Cocaine; Depression, Chemical; Electric Stimulation; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Reinforcement, Psychology; Rimonabant; Selective Serotonin Reuptake Inhibitors; Self Stimulation

2001
Evaluation of the reinforcing effects of the cannabinoid CB1 receptor antagonist, SR141716, in rhesus monkeys.
    European journal of pharmacology, 2002, Jan-25, Volume: 435, Issue:2-3

    Topics: Animals; Cannabinoids; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Macaca mulatta; Male; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Reinforcement Schedule; Rimonabant; Self Administration

2002
WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation.
    Behavioural brain research, 2003, May-15, Volume: 141, Issue:2

    Topics: Algorithms; Animals; Benzoxazines; Brain; Cocaine; Conditioning, Operant; Electrodes, Implanted; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Reinforcement, Psychology; Reward; Rimonabant; Self Stimulation; Stimulation, Chemical

2003
The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801.
    Brain research bulletin, 2003, Jul-15, Volume: 61, Issue:2

    Topics: Anesthetics, Local; Animals; Cannabinoid Receptor Modulators; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Cannabinoid; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Rimonabant

2003
Discriminative stimulus effects of the cannabinoid antagonist, SR 141716A, in delta -sup-9-tetrahydrocannabinol-treated rhesus monkeys.
    Experimental and clinical psychopharmacology, 2003, Volume: 11, Issue:4

    Topics: Anesthetics; Animals; Behavior, Animal; Cannabinoids; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Female; Ketamine; Macaca mulatta; Male; Photic Stimulation; Piperidines; Psychotropic Drugs; Pyrazoles; Rimonabant; Substance Withdrawal Syndrome

2003
Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats.
    Psychopharmacology, 2004, Volume: 175, Issue:3

    Topics: Amphetamine; Animals; Cannabidiol; Cocaine; Conditioning, Operant; Dronabinol; Extinction, Psychological; Learning; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant

2004
Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons.
    Biological psychiatry, 2004, Jul-15, Volume: 56, Issue:2

    Topics: Action Potentials; Age Factors; Amphetamine; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Critical Period, Psychological; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Electrophysiology; Illicit Drugs; Male; Morphine; Morpholines; Naphthalenes; Nerve Net; Neurons; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Ventral Tegmental Area

2004
CB1 receptor agonist and heroin, but not cocaine, reinstate cannabinoid-seeking behaviour in the rat.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: Animals; Behavior, Animal; Benzoxazines; Cannabinoids; Cocaine; Extinction, Psychological; Heroin; Male; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Rimonabant; Self Administration; Time Factors

2004
Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cannabinoid Receptor Antagonists; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Movement; Piperidines; Pyrazoles; Receptors, Cannabinoid; Reinforcement, Psychology; Rimonabant; Self Administration; Substance Abuse, Intravenous

2005
Lack of CB1 cannabinoid receptor impairs cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:9

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Feeding Behavior; Food Deprivation; Mice; Mice, Knockout; Microdialysis; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Self Administration; Time Factors; Water Deprivation

2005
The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Jun-08, Volume: 25, Issue:23

    Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cocaine; Endocannabinoids; Infusions, Intravenous; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Saimiri; Self Administration; Stereoisomerism; Substance-Related Disorders

2005
WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function.
    European journal of pharmacology, 2005, Jul-04, Volume: 517, Issue:1-2

    Topics: Animals; Benzoxazines; Cocaine; Dose-Response Relationship, Drug; Male; Morpholines; Motor Activity; Naphthalenes; Ondansetron; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Rimonabant; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists

2005
Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:4

    Topics: Analgesics, Opioid; Animals; Area Under Curve; Behavior, Animal; Cannabinoids; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine; Drug Administration Routes; Drug Interactions; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Neural Pathways; Piperidines; Pyrazoles; Rats; Rats, Wistar; Reinforcement, Psychology; Rimonabant; Self Administration; Time Factors

2006
Chronic cocaine sensitizes striatal GABAergic synapses to the stimulation of cannabinoid CB1 receptors.
    The European journal of neuroscience, 2007, Volume: 25, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine Uptake Inhibitors; Dronabinol; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Male; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Synapses

2007
Analogs of SR-141716A (Rimonabant) alter d-amphetamine-evoked [3H] dopamine overflow from preloaded striatal slices and amphetamine-induced hyperactivity.
    Life sciences, 2007, Jun-13, Volume: 81, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Hyperkinesis; Male; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Time Factors; Tritium

2007
Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:7

    Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Reinforcement Schedule; Reward; Rimonabant; Self Administration

2008
Context-specific reversal of cocaine sensitization by the CB1 cannabinoid receptor antagonist rimonabant.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:11

    Topics: Animals; Behavior, Addictive; Cocaine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2008
Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:7

    Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Endocannabinoids; Male; Morpholines; Motor Activity; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Stimulation; Synaptic Transmission

2008
Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice.
    Psychopharmacology, 2009, Volume: 204, Issue:1

    Topics: Animals; Cocaine; Dopamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleus Accumbens; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2009
A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Apr-15, Volume: 29, Issue:15

    Topics: Animals; Behavior, Addictive; Cannabinoid Receptor Modulators; Cocaine; Endocannabinoids; Male; Motivation; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Self Administration

2009
The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse.
    Drug and alcohol dependence, 2009, Dec-01, Volume: 105, Issue:3

    Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corn Oil; Cues; Dietary Sucrose; Disease Models, Animal; Extinction, Psychological; Food, Formulated; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Recurrence; Reinforcement Schedule; Rimonabant; Self Administration; Water

2009
Sex and cannabinoid CB1 genotype differentiate palatable food and cocaine self-administration behaviors in mice.
    Behavioural pharmacology, 2009, Volume: 20, Issue:7

    Topics: Animals; Cocaine; Conditioning, Operant; Corn Oil; Feeding Behavior; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement Schedule; Rimonabant; Self Administration; Sex Characteristics

2009
Intra-accumbens rimonabant is rewarding but induces aversion to cocaine in cocaine-treated rats, as does in vivo accumbal cannabinoid CB1 receptor silencing: critical role for glutamate receptors.
    Neuroscience, 2010, May-05, Volume: 167, Issue:2

    Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Drug Inverse Agonism; Gene Silencing; Lentivirus; Ligands; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Glutamate; Reward; Rimonabant

2010
Effects of cannabinoid CB₁ receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice.
    Behavioural brain research, 2011, Feb-02, Volume: 217, Issue:1

    Topics: Animals; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Methamphetamine; Mice; Mice, Inbred Strains; Piperidines; Pyrazoles; Reward; Rimonabant

2011
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:3

    Topics: Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Illicit Drugs; In Vitro Techniques; Male; Mecamylamine; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors; Ventral Tegmental Area

2011
Sensitization to cocaine is inhibited after intra-accumbal GR103691 or rimonabant, but it is enhanced after co-infusion indicating functional interaction between accumbens D(3) and CB1 receptors.
    Psychopharmacology, 2011, Volume: 214, Issue:4

    Topics: Animals; Biphenyl Compounds; Cocaine; Dose-Response Relationship, Drug; Drug Inverse Agonism; Drug Synergism; Infusions, Intraventricular; Motor Activity; Neuronal Plasticity; Nucleus Accumbens; Piperazines; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Dopamine D3; Rimonabant

2011
Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Dopaminergic Neurons; Electric Stimulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tegmentum Mesencephali; Time Factors; Ventral Tegmental Area

2012
Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.
    Psychopharmacology, 2012, Volume: 222, Issue:3

    Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Dronabinol; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tropanes

2012
Cocaine-induced endocannabinoid release modulates behavioral and neurochemical sensitization in mice.
    Addiction biology, 2015, Volume: 20, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cannabinoid Receptor Antagonists; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Endocannabinoids; Mice; Microdialysis; Motor Activity; Nucleus Accumbens; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2015
Endocannabinoids promote cocaine-induced impulsivity and its rapid dopaminergic correlates.
    Biological psychiatry, 2014, Mar-15, Volume: 75, Issue:6

    Topics: Animals; Cannabinoid Receptor Antagonists; Cocaine; Conditioning, Operant; Cues; Dopamine; Dopaminergic Neurons; Endocannabinoids; Impulsive Behavior; Male; Motor Activity; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Time Factors

2014
Medial prefrontal cannabinoid CB1 receptors modulate consolidation and extinction of cocaine-associated memory in mice.
    Psychopharmacology, 2015, Volume: 232, Issue:10

    Topics: Animals; Cannabinoid Receptor Antagonists; Cocaine; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Mice; Mice, Inbred C57BL; Piperidines; Prefrontal Cortex; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2015
Effects of rimonabant on the development of single dose-induced behavioral sensitization to ethanol, morphine and cocaine in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Apr-03, Volume: 58

    Topics: Akathisia, Drug-Induced; Animals; Animals, Outbred Strains; Anxiety; Cannabinoid Receptor Antagonists; Central Nervous System Depressants; Cocaine; Depression; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Morphine; Motor Activity; Narcotics; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance-Related Disorders

2015
Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys.
    Psychopharmacology, 2016, Volume: 233, Issue:10

    Topics: Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Drug-Seeking Behavior; Endocannabinoids; Male; Nicotine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Reinforcement, Psychology; Reward; Rimonabant; Saimiri; Self Administration

2016
Attenuation of Cocaine-Induced Conditioned Place Preference and Motor Activity via Cannabinoid CB2 Receptor Agonism and CB1 Receptor Antagonism in Rats.
    The international journal of neuropsychopharmacology, 2017, 03-01, Volume: 20, Issue:3

    Topics: Animals; Cannabinoids; Cocaine; Conditioning, Classical; Indoles; Male; Motor Activity; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant

2017
Post-sensitization treatment with rimonabant blocks the expression of cocaine-induced behavioral sensitization and c-Fos protein in mice.
    Pharmacology, biochemistry, and behavior, 2017, Volume: 156

    Topics: Animals; Behavior, Animal; Cannabinoid Receptor Antagonists; Cocaine; Locomotion; Male; Mice; Piperidines; Proto-Oncogene Proteins c-fos; Pyrazoles; Rimonabant

2017
Endogenous dopamine and endocannabinoid signaling mediate cocaine-induced reversal of AMPAR synaptic potentiation in the nucleus accumbens shell.
    Neuropharmacology, 2018, 03-15, Volume: 131

    Topics: Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Antagonists; Cocaine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Flupenthixol; Long-Term Synaptic Depression; Male; Mice; Morpholines; Naphthalenes; Nucleus Accumbens; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rimonabant; Synaptic Transmission

2018
Cocaine-induced increases in motivation require 2-arachidonoylglycerol mobilization and CB1 receptor activation in the ventral tegmental area.
    Neuropharmacology, 2021, 08-01, Volume: 193

    Topics: Animals; Arachidonic Acids; Cocaine; Conditioning, Operant; Endocannabinoids; Female; Glycerides; Male; Motivation; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Administration; Ventral Tegmental Area

2021
Sex differences in cocaine-associated memory: The interplay between CB
    Psychoneuroendocrinology, 2021, Volume: 133

    Topics: Animals; Cannabinoid Receptor Antagonists; Cocaine; Cocaine-Related Disorders; Estradiol; Female; Male; Mice; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Rimonabant; Sex Characteristics

2021
Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats.
    Endocrinology, 2008, Volume: 149, Issue:5

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Candy; Diet; Eating; Energy Metabolism; Fatty Acids, Nonesterified; Female; Liver Glycogen; Male; Photoperiod; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Time Factors; Weight Loss

2008