cocaine has been researched along with sirolimus in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Glick, SD; Huang, Y; McCallum, SE; Wu, J | 1 |
| Bailey, J; Ma, D; Szumlinski, KK | 1 |
| Gao, Y; Li, Y; Lin, J; Liu, L; Peng, S; Tan, Y; Wen, Q; Zheng, C | 1 |
| Charnley, JL; Dayas, CV; Dickson, PW; James, MH; Levi, EM; Ong, LK; Quinn, RK; Smith, DW | 1 |
| Aguiar, DC; Crippa, JA; de Oliveira, AC; Gobira, PH; Gonçalves, BD; Moreira, FA; Santos, RP; Vieira, LB; Vilela, LR | 1 |
| Dayas, CV; Dickson, PW; James, MH; Levi, EM; Ong, LK; Quinn, RK; Smith, DW | 1 |
| Betuing, S; Boudier, T; Caboche, J; Dos Santos, M; Forget, B; Garcia Perez, MA; Heck, N; Salery, M; Vanhoutte, P | 1 |
| Caffino, L; Castillo Díaz, F; Fumagalli, F; Mottarlini, F; Rizzi, B; Targa, G | 1 |
9 other study(ies) available for cocaine and sirolimus
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization.
Topics: Animals; Anti-Bacterial Agents; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Female; Rats; Rats, Sprague-Dawley; Sirolimus; TOR Serine-Threonine Kinases | 2011 |
Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Drug Interactions; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Motor Activity; Reinforcement, Psychology; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2012 |
Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Cues; Drug-Seeking Behavior; Ethanol; Male; Maze Learning; Memory; Morphine; Motor Activity; Protein Kinase Inhibitors; Rats; Reward; Sirolimus | 2014 |
mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Gene Expression Regulation; Mechanistic Target of Rapamycin Complex 1; Motor Activity; Multiprotein Complexes; Nucleus Accumbens; Rats; Receptors, AMPA; Recurrence; Reinforcement, Psychology; Self Administration; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release.
Topics: Anesthetics, Local; Animals; Antiemetics; Cannabidiol; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Immunosuppressive Agents; Indoles; Male; Mice; Seizures; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum.
Topics: Animals; Behavior, Animal; Body Weight; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Gene Expression Regulation; Male; Mechanistic Target of Rapamycin Complex 1; Motivation; Multiprotein Complexes; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Sirolimus; TOR Serine-Threonine Kinases; Ventral Striatum | 2016 |
Rapid Synaptogenesis in the Nucleus Accumbens Is Induced by a Single Cocaine Administration and Stabilized by Mitogen-Activated Protein Kinase Interacting Kinase-1 Activity.
Topics: Animals; Cocaine; Dendritic Spines; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Luminescent Proteins; MAP Kinase Kinase 1; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neostriatum; Neurogenesis; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Sirolimus; Synapses; Vesicular Glutamate Transport Protein 1 | 2017 |
Recency memory is altered in cocaine-withdrawn adolescent rats: Implication of cortical mTOR signaling.
Topics: Adolescent; Animals; Cocaine; Humans; Mammals; Memory; Prefrontal Cortex; Rats; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2023 |