cocaine has been researched along with s,n,n'-tripropylthiocarbamate in 1049 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (2.38) | 18.7374 |
| 1990's | 94 (8.96) | 18.2507 |
| 2000's | 287 (27.36) | 29.6817 |
| 2010's | 511 (48.71) | 24.3611 |
| 2020's | 132 (12.58) | 2.80 |
| Authors | Studies |
|---|---|
| Johanson, CE | 1 |
| Esposito, RU; Kornetsky, C | 1 |
| Beitner-Johnson, D; Guitart, X; Nestler, EJ | 2 |
| Koob, GF; Maldonado-Lopez, R; Pulvirenti, L | 1 |
| Koob, GF; Maldonado-Lopez, R; Robledo, P | 1 |
| Calcagnetti, DJ; Schechter, MD | 2 |
| Brown, RM | 1 |
| Frank, RA; Kokoris, D; Manderscheid, PZ; Panicker, S; Williams, HP | 1 |
| Fratta, W; Gessa, GL; Kuzmin, A; Martellotta, MC; Zvartau, E | 1 |
| Bauco, P; Carlezon, WA; Trojniar, W; Wise, RA | 1 |
| Clow, DW; Hammer, RP; Spear, LP | 1 |
| Beitner-Johnson, D; Nestler, EJ | 1 |
| Boja, JW; Kuhar, MJ; Ritz, MC | 1 |
| Koob, GF; Markou, A | 1 |
| Corbett, D | 1 |
| Clow, DW; Hammer, RP | 1 |
| Huston-Lyons, D; Kornetsky, C; Porrino, LJ | 1 |
| Carney, JM; Seale, TW | 1 |
| Horger, BA; Schenk, S; Shelton, K | 1 |
| Kokkinidis, L; McCarter, BD | 1 |
| Hammer, RP | 1 |
| Lett, BT | 1 |
| Frank, RA; Zubrycki, E | 1 |
| Holden, C | 2 |
| Mackey, WB; van der Kooy, D | 1 |
| Dackis, CA; Gold, MS | 2 |
| Seifert, WF; van Ree, JM; van Wolfswinkel, L | 1 |
| Gawin, FH | 1 |
| Hernandez, L; Hoebel, BG | 1 |
| Frank, RA; Martz, S; Pommering, T | 1 |
| Bain, GT; Kornetsky, C | 1 |
| Holman, EW; Smith, CA | 1 |
| Nomikos, GG; Spyraki, C; Varonos, DD | 1 |
| Badalamenti, JI; Glick, SD | 1 |
| Bergman, J; Johanson, CE | 1 |
| Kornetsky, C | 1 |
| Barr, GA; Lithgow, T | 1 |
| Winger, G; Woods, JH | 1 |
| Collier, HO | 1 |
| Crow, TJ | 1 |
| Wise, RA | 3 |
| Britt, MD; Wise, RA | 1 |
| Heidbreder, C; Shippenberg, TS | 2 |
| Parker, JL; van der Kooy, D | 1 |
| Gong, W; Justice, JB; Neill, DB | 2 |
| Misawa, M; Suzuki, T | 1 |
| Tella, SR | 1 |
| Gardner, EL; Lepore, M; Lowinson, J; Vorel, SR | 1 |
| Sevarino, KA; Walker, JR | 1 |
| Brown, EE; Fibiger, HC | 1 |
| Masukawa, Y; Misawa, M; Suzuki, T | 1 |
| Bradberry, CW; Jatlow, PI; Nobiletti, JB | 1 |
| Kelley, AE; Maldonado-Irizarry, CS; Stellar, JR | 1 |
| Hemby, SE; Hubert, GW; Jones, GH; Justice, JB; Neill, DB | 1 |
| Kiyatkin, EA; Stein, EA | 1 |
| Bozarth, MA; Morris, M; Pudiak, CM | 1 |
| Kling-Petersen, T; Svensson, K | 1 |
| Hammer, RP; Koob, GF; Markou, A; Pires, WS | 1 |
| Babovic-Vuksanovic, D; de Vries, TJ; Elmer, G; Shippenberg, TS | 1 |
| Heidbreder, C; LeFevour, A; Shippenberg, TS | 1 |
| Duvauchelle, C; Kornetsky, C | 1 |
| Fowler, JS; Hitzemann, R; Volkow, ND; Wang, GJ | 1 |
| Mash, DC; Staley, JK | 1 |
| Aigner, TG; Bowman, EM; Richmond, BJ | 1 |
| Biała, G; Langwiński, R | 1 |
| Balducci, C; Koob, GF; Pulvirenti, L | 1 |
| Comings, DE; Gade, R; Johnson, P; MacMurray, J; Muhleman, D; Saucier, G; Verde, R | 1 |
| Costentin, J; Duterte-Boucher, D; Le Pen, G | 2 |
| Abrahamsen, GC; Carr, KD | 1 |
| Bauco, P; Ranaldi, R; Wise, RA | 1 |
| Miner, LL | 1 |
| English, JA; Weed, MR; Woolverton, WL | 1 |
| Dewey, SL; Kornetsky, C; Kushner, SA | 2 |
| Bauco, P; Wise, RA | 1 |
| Boswell, KJ; Gonzales, PM; Hubbell, CL; Reid, LD | 1 |
| Bardo, MT | 1 |
| Dashevsky, BA; Frank, RA; Grocki, S; Kehne, JH; Schmidt, CJ; Sorensen, SM; Tsibulsky, VL | 1 |
| Chang, JY; Janak, PH; Woodward, DJ | 1 |
| Hecht, GS; Spear, LP; Spear, NE | 2 |
| LeFevour, A; Shippenberg, TS; Thompson, AC | 1 |
| Boedeker, KL; Cramer, CM; Gardell, LR; Harris, JR; Hubbell, CL; Reid, LD | 1 |
| Lesch, KP; Li, XF; Murphy, DL; Revay, R; Sora, I; Takahashi, N; Uhl, GR; Wichems, C; Zeng, Z | 1 |
| Davidson, ES; Schenk, S | 1 |
| Munn, E; Ranaldi, R | 1 |
| Bibi, R; Gee, F; Peoples, LL; West, MO | 1 |
| Costentin, J; Daoust, M; Duterte-Boucher, D; Le Pen, G | 1 |
| Brodkin, ES; Carlezon, WA; Duman, RS; Hiroi, N; Lane-Ladd, SB; Nestler, EJ; Neve, RL; Olson, VG; Thome, J | 1 |
| Schmidt, WJ; Tzschentke, TM | 2 |
| Patkina, NA; Zvartau, EE | 1 |
| Caine, SB; Everitt, BJ; Matthews, K; Robbins, TW | 1 |
| Barron, S; Hansen-Trench, LS; Segar, TM; Willford, JA | 1 |
| Harrison, AA; Koob, GF; Markou, A; Parsons, LH | 1 |
| Horger, BA; Taylor, JR | 1 |
| Kosofsky, BE; Malanga, CJ | 1 |
| Oglesby, MW; Ripley, TL; Rocha, BA; Stephens, DN | 1 |
| Berhow, MT; Horger, BA; Iyasere, CA; Messer, CJ; Nestler, EJ; Taylor, JR | 1 |
| Fredholm, BB; Johansson, B; Kuzmin, A; Zvartau, EE | 1 |
| Anstrom, K; Azarov, A; Chang, JY; Janak, P; Woodward, DJ | 2 |
| Breiter, HC; Rosen, BR | 1 |
| Grubb, MC; Keys, AS; Kinney, AE; Mark, GP | 1 |
| Cunningham, CL; Dickinson, SD; Grahame, NJ; McMullin, CS; Okorn, DM | 1 |
| Gomez, F; Grigson, PS | 1 |
| Kelley, BM; Middaugh, LD | 1 |
| Bardo, MT; Bevins, RA | 1 |
| Donovan, DM; Kirstein, CL; Kostic, V; Miner, LL; Perry, MP; Philpot, RM; Przedborski, S; Revay, RS; Rothman, RB; Schindler, CW; Sharpe, LG; Uhl, GR | 1 |
| Clarke, L; Coffin, V; Cornish, J; Glue, P; Kampman, K; Kaplan, HL; O'Brien, CP; Poole, S; Romach, MK; Sellers, EM; Somer, GR | 1 |
| Koob, GF | 1 |
| Baldo, BA; Koob, GF; Markou, A | 1 |
| Ashby, CR; Gardner, EL; Horan, B | 1 |
| Brené, S; Olson, L; Werme, M | 1 |
| Grimm, JW; See, RE | 1 |
| Appel, SB; Brodie, MS; Bunney, EB | 1 |
| Glowa, JR; LeSage, MG; Stafford, D | 1 |
| Karanian, DA; Self, DW; Sutton, MA | 1 |
| Carelli, RM; Crumling, AJ; Ijames, SG | 1 |
| De Felipe, C; Hunt, SP; Murtra, P; Sheasby, AM | 1 |
| Schmidt, WJ; Tzchentke, TM | 1 |
| Kastellakis, A; Nomikos, G; Panagis, G; Spyraki, C | 1 |
| Cossu, G; Fattore, L; Fratta, W; Martellotta, MC | 1 |
| Ohkuma, S; Shimosato, K | 1 |
| Le Foll, B; Schwartz, JC; Sokoloff, P | 1 |
| Deadwyler, SA; Nicola, SM | 1 |
| Johnson, KM; Kozikowski, AP; Prakash, KR; Trzcinska, M | 1 |
| Kiyatkin, DE; Kiyatkin, EA; Rebec, GV | 1 |
| Martin-Fardon, R; Maurice, T; Romieu, P | 1 |
| Dickinson, A; Everitt, BJ; Miles, FJ; Olmstead, MC; Parkinson, JA | 1 |
| Cabeza de Vaca, S; Carr, KD; Kim, GY | 1 |
| Ledent, C; Maldonado, R; Martin, M; Parmentier, M; Valverde, O | 1 |
| Besson, MJ; Caboche, J; Corvol, JC; Maldonado, R; Pages, C; Valjent, E | 1 |
| Böhme, GA; Cossu, G; Fattore, L; Fratta, W; Imperato, A; Ledent, C; Parmentier, M | 1 |
| Akins, CK; Levens, N | 1 |
| Babich, JW; Choi, SW; Elmaleh, DR; Hanson, RN; Johnson, KM; Kozikowski, AP; Pimentel, P; Prakash, KR; Smith, MP; Stellar, JR; Tamiz, AP; Trzcińska, M; Zhang, J | 1 |
| Andrews, AM; Hall, FS; Itokawa, M; Lesch, KP; Li, XF; Murphy, DL; Sora, I; Uhl, GR; Wei, HB; Wichems, C | 1 |
| Gardner, EL; Hayes, RJ; Liu, X; Spector, JA; Vorel, SR | 1 |
| Grimm, JW; Kruzich, PJ; See, RE | 1 |
| Ranaldi, R; Wise, RA | 1 |
| Caron, MG; Gainetdinov, RR; Premont, RT | 1 |
| Binzak, JM; Kelley, AE; Schroeder, BE | 1 |
| Ciraulo, DA; Foye, M; Knapp, CM; Kornetsky, C; Lee, K | 1 |
| Allan, AM; Chynoweth, J; Engel, SR; Galindo, R; Savage, DD | 1 |
| Dockstader, CL; van der Kooy, D | 1 |
| Hodge, CW; Koenig, HN; Nannini, MA; Olive, MF | 1 |
| Dackis, CA; O'Brien, CP | 1 |
| Andersen, SL; Arvanitogiannis, A; Carlezon, WA; LeBlanc, C; Pliakas, AM | 1 |
| Belluzzi, JD; Manzardo, AM; Stein, L | 1 |
| De La Garza, R; Jentsch, JD; Olausson, P; Taylor, JR | 1 |
| Hall, FS; Sora, I; Uhl, GR | 1 |
| Fuchs, RA; Neisewander, JL; Rice, HJ; Weber, SM | 1 |
| Bozarth, MA; Pudiak, CM | 1 |
| Blanc, G; Cotecchia, S; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP; Trovero, F | 1 |
| Mori, T; Nagase, H; Narita, M; Nomura, M; Suzuki, T | 1 |
| Brown, G; Stephens, DN | 1 |
| Dobrovitsky, V; Duarte, A; Froestl, W; Pimentel, P; Stellar, JR; Trzcińska, M | 1 |
| Grigson, PS; Twining, RC | 1 |
| Ahmed, SH; Kenny, PJ; Koob, GF; Markou, A | 1 |
| Contarino, A; Gold, LH; Kieffer, BL; Koob, GF; Matthes, HW; Picetti, R | 1 |
| Carlezon, WA; Gilliss, B; Malanga, CJ; Pieper, JO | 1 |
| Martin-Fardon, R; Matsumoto, RR; Maurice, T; Romieu, P | 1 |
| Li, N; Sorg, BA; Wu, WR | 1 |
| Farabee, D; Huber, A; Ling, W; McCann, M; Rawson, RA; Reiber, C; Shoptaw, S | 1 |
| Grimm, JW; Hope, BT; Shaham, Y | 1 |
| Rademacher, DJ; Steinpreis, RE | 1 |
| Ashby, CR; Gardner, EL; Hagan, JJ; Hayes, R; Liu, X; Middlemiss, DN; Paul, M; Stemp, G; Vorel, SR | 1 |
| Hodge, CW; Kelley, SP | 1 |
| McGeehan, AJ; Olive, MF | 1 |
| Choi, KH; Karanian, DA; Monteggia, LM; Neve, RL; Schad, CA; Schmidt, EF; Self, DW; Simmons, D; Sutton, MA; Whisler, K | 1 |
| Kenny, PJ; Koob, GF; Markou, A; Polis, I | 1 |
| Gál, K; Gyertyán, I | 1 |
| Brown, PL; Kiyatkin, EA | 1 |
| Grimm, JW; Hayashi, T; Hope, BT; Lu, L; Shaham, Y; Su, TP | 1 |
| Platt, DM; Rodefer, JS; Rowlett, JK; Spealman, RD | 1 |
| Cole, JC; Marsden, CA; O'Shea, E; Sumnall, HR | 1 |
| Hotsenpiller, G; Wolf, ME | 1 |
| Fabian, SJ; Festa, ED; Jenab, S; Kemen, LM; Quinones-Jenab, V; Russo, SJ | 1 |
| Bowen, WD; Martin-Fardon, R; Maurice, T; Romieu, P | 1 |
| Nomikos, GG; Panagis, G; Vlachou, S | 1 |
| Achat-Mendes, C; Anderson, KL; Itzhak, Y | 1 |
| Chavkin, C; Marton-Popovici, M; McLaughlin, JP | 1 |
| Clarke, PB; Sellings, LH | 1 |
| Capó-Ramos, DE; Febo, M; González-Rodríguez, LA; González-Segarra, NY; Segarra, AC | 1 |
| Collu, M; Fadda, P; Fratta, W; Fresu, A; Scherma, M | 1 |
| Fabian, SJ; Festa, ED; Gazi, FM; Jenab, S; Kraish, M; Quiñones-Jenab, V; Russo, SJ | 1 |
| Fabbricatore, AT; Ghitza, UE; Pawlak, AP; Prokopenko, V; West, MO | 1 |
| De Felipe, C; Gadd, CA; Hunt, SP; Murtra, P | 1 |
| Ikemoto, S | 2 |
| McClung, CA; Nestler, EJ | 1 |
| Alleweireldt, AT; Neisewander, JL; Rice, HJ; Weber, SM; Zavala, AR | 1 |
| Kenny, PJ; Koob, GF; Markou, A | 1 |
| Meyers, RA; Neisewander, JL; Zavala, AR | 1 |
| Bohn, LM; Caron, MG; Dykstra, LA; Gainetdinov, RR; Lefkowitz, RJ; Medvedev, IO; Sotnikova, TD | 1 |
| Blendy, JA; Kuo, YC; Walters, CL | 1 |
| Griffin, WC; Middaugh, LD | 1 |
| Carelli, RM; Wondolowski, J | 1 |
| Boutrel, B; Gasparini, F; Harrison, AA; Kenny, PJ; Koob, GF; Markou, A; Paterson, NE; Semenova, S; Skoubis, PD | 1 |
| Kalivas, PW; Middaugh, LD; Szumlinski, KK; Toda, S; Worley, PF | 1 |
| Butelman, ER; Ho, A; Kreek, MJ; Schlussman, SD; Zhang, Y | 1 |
| Lee, DY; Quinlan, MG; Ranaldi, R; Sharf, R; Wise, RA | 1 |
| Arbuckle, MI; Beaulieu, JM; Caron, MG; Cyr, M; Gainetdinov, RR; Grant, SG; Sotnikova, TD; Torres, GE; Yao, WD | 1 |
| Cheer, J; Deadwyler, SA; Hampson, RE; Hayashizaki, S | 1 |
| Buhot, MC; Cazala, P; David, V; Ichaye, M; Segu, L | 1 |
| Fields, HL; Hjelmstad, GO; Kim, JA; Pollak, KA | 1 |
| Boilet, V; Cador, M; Dias, C; Huitelec, E; Lachize, S | 1 |
| Roth-Deri, I; Schindler, CJ; Yadid, G | 1 |
| Broadbear, JH; Winger, G; Woods, JH | 1 |
| Baptista, MA; Martin-Fardon, R; Weiss, F | 1 |
| Festa, ED; Kraish, M; Nazarian, A; Quinones-Jenab, V; Russo, SJ | 1 |
| Ait-Daoud, N; Johnson, BA; Mauldin, JB; Roache, JD; Wells, LT | 1 |
| Huber, R; Panksepp, JB | 1 |
| Gardner, EL; Hayes, RJ | 1 |
| Busse, GD; Riley, AL | 1 |
| Robinson, TE | 1 |
| Belin, D; Deroche-Gamonet, V; Piazza, PV | 1 |
| Everitt, BJ; Vanderschuren, LJ | 1 |
| Babovic, D; Daoust, M; Houchi, H; Ledent, C; Naassila, M; Pierrefiche, O | 1 |
| Gill, BM; Knapp, CM; Kornetsky, C | 1 |
| Belluzzi, JD; Leslie, FM; Wang, R | 1 |
| Duvauchelle, CL; Ikegami, A | 1 |
| Drgonova, J; Goeb, M; Hall, FS; Li, XF; Sora, I; Uhl, GR | 1 |
| Herzig, V; Schmidt, WJ | 1 |
| Brown, S; Chambers, RA; Jones, RM; Taylor, JR | 1 |
| Morgan, D; Roberts, DC; Ward, SJ | 1 |
| Fujio, M; Minami, M; Nakagawa, T; Ozawa, T; Satoh, M | 1 |
| Bidlack, JM; Mello, NK; Negus, SS; Stevenson, GW; Wentland, MP | 1 |
| Boutrel, B; Gasparini, F; Kenny, PJ; Koob, GF; Markou, A | 1 |
| Brown, G; Le Merrer, J; Mead, AN; Stephens, DN | 1 |
| Febo, M; Ferris, CF; Harder, JA; Kulkarni, P; Messenger, TL; Sullivan, JM | 1 |
| Brabant, C; Quertemont, E; Tirelli, E | 1 |
| Ahmed, SH; Koob, GF | 1 |
| Amalric, M; Baunez, C; Cador, M; Dias, C | 1 |
| Cryan, JF; Froestl, W; Markou, A; Slattery, DA | 1 |
| Kosten, TA; Zhang, XY | 1 |
| Alvaro, JD; Duman, RS; Haile, C; Han, G; Hruby, VJ; Hsu, R; Nestler, EJ; Newton, SS; Taylor, JR | 1 |
| Norman, AB; Tsibulsky, VL | 1 |
| Brackett, DJ; Chen, GD; Lerner, MR; Liu, Y; Matsumoto, RR | 1 |
| Arnold, JC | 1 |
| Antkiewicz-Michaluk, L; Filip, M; Michaluk, J; Papla, I; Patsenka, A; Przegaliński, E; Romańska, I; Vetulani, J | 1 |
| Barrot, M; Bolanos, CA; Edwards, S; Eisch, AJ; Hughes, T; Nestler, EJ; Neve, RL; Olson, VG; Self, DW; Zabetian, CP | 1 |
| Blendy, JA; Cleck, JN; Kuo, YC; Walters, CL | 1 |
| Cooper, DC; McClung, CA; Nestler, EJ; Sidiropoulou, K; Takahashi, JS; Vitaterna, M; White, FJ | 1 |
| Heusner, CL; Palmiter, RD | 1 |
| Capuani, EM; Herzig, V; Kovar, KA; Schmidt, WJ | 1 |
| Castañé, A; Ledent, C; Maldonado, R; Parmentier, M; Soria, G; Valverde, O | 1 |
| Gong, JP; Grumet, M; Hall, FS; Ishiguro, H; Liu, QR; Morales, M; Sakurai, T; Uhl, GR; Ujike, H | 1 |
| Marinelli, M | 1 |
| Cheng, R; George, SR; Karasinska, JM; O'Dowd, BF | 1 |
| Ashby, CR; Gardner, EL; Gilbert, JG; Gitajn, L; Newman, AH; Pak, AC; Peng, XQ; Xi, ZX | 1 |
| Cui, CL; Han, JS | 1 |
| Bussolino, DF; Cuadra, GR; Orsingher, OA; Valdomero, A | 1 |
| Jurd, R; Ron, D | 1 |
| Boutrel, B; de Lecea, L; Kenny, PJ; Koob, GF; Markou, A; Martin-Fardon, R; Specio, SE | 1 |
| Bornovalova, MA; Daughters, SB; Hernandez, GD; Lejuez, CW; Richards, JB | 1 |
| Gonsai, K; Gonzalez, G; Kosten, TR; Martell, B; Oliveto, A; Petry, N; Poling, J; Sofuoglu, M | 1 |
| Becker, N; Mead, AN; Stephens, DN; Zamanillo, D | 1 |
| Edwards, S; Fuller, DC; Orsulak, PJ; Self, DW; Whisler, KN | 1 |
| Duong, TQ; Febo, M; Ferris, CF; Luo, F; Schmidt, KF; Shen, Q; Sicard, KM; Stein, EA | 1 |
| Augustine, GJ; Gitler, D; Greengard, P; Phillips, PE; Seipel, AT; Venton, BJ; Wetsel, WC; Wightman, RM | 1 |
| Gosnell, HB; Grueter, BA; Landreth, GE; Nekrasova, T; Olsen, CM; Schramm-Sapyta, NL; Winder, DG | 1 |
| Katz, ES; Mantsch, JR | 1 |
| Chocyk, A; Czyrak, A; Wedzony, K | 1 |
| Ravna, AW | 1 |
| Aguilar, MA; Estelles, J; Maldonado, C; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Chen, R; Ching, S; Gu, HH; Han, DD; Hill, ER; Nottoli, T; Quan, N; Stephens, RL; Tilley, MR; Wei, H; Zhou, F; Zhou, FM | 1 |
| Jaworski, JN; Jones, DC | 1 |
| Feltenstein, MW; Fuchs, RA; See, RE | 1 |
| Cui, D; Ding, J; Duan, S; Fei, J; Guo, L; Shi, J; Xu, L | 1 |
| Limebeer, CL; Parker, LA; Slomke, J | 1 |
| Graham, DL; Hendryx, A; Hoppenot, R; Self, DW | 1 |
| Antkiewicz-Michaluk, L; Filip, M; Michaluk, J; Przegaliński, E; Romańska, I; Vetulani, J | 1 |
| Jasmin, L; Narasaiah, M; Tien, D | 1 |
| Gardner, EL; Gilbert, JG; Li, X; Pak, AC; Peng, XQ; Xi, ZX | 1 |
| Coolen, EJ; Cools, AR; Ellenbroek, BA; van der Kam, EL | 1 |
| Aguilar, MA; Estelles, J; Maldonado, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Foltin, RW | 1 |
| Francis, DD; Kozel, M; Kuhar, MJ; Moffett, MC; Plotsky, P; Vicentic, A | 1 |
| Adler, KJ; Badanich, KA; Kirstein, CL | 1 |
| Bechtholt, AJ; Berger, SP; Finn, DA; Grubb, MC; Kinney, AE; Mader, SL; Mark, GP; Zhu, X | 1 |
| Bernardi, RE; Ettenberg, A | 2 |
| Anaclet, C; Brabant, C; Lin, JS; Ohtsu, H; Quertemont, E; Tirelli, E | 1 |
| Manzardo, AM; O'Dell, LE; Parsons, LH; Polis, I; Stouffer, DG | 1 |
| Black, YD; Di Pietro, NC; Kantak, KM | 1 |
| Cryan, JF; Markou, A; Slattery, DA | 1 |
| Bissonette, GB; Gugsa, N; Roesch, MR; Schoenbaum, G; Takahashi, Y | 1 |
| Bland, ST; Der-Avakian, A; Hutchinson, MR; Maier, SF; Rozeske, RR; Tamblyn, JP; Watkins, LR | 1 |
| Bland, ST; Der-Avakian, A; Maier, SF; Rozeske, RR; Watkins, LR | 1 |
| Carrigan, KA; Dykstra, LA | 1 |
| Ettenberg, A; Guzman, D | 1 |
| Aujla, H; Bowen, WD; Martin-Fardon, R; Maurice, T; Weiss, F | 1 |
| Filip, M; Frankowska, M; Gołda, A; Przegaliński, E; Zaniewska, M | 1 |
| Badiani, A; Caprioli, D; Celentano, M; Nencini, P; Paolone, G; Testa, A | 1 |
| Ahmed, SH; Cador, M; Zittel-Lazarini, A | 1 |
| Duvauchelle, CL; Reveron, ME; Seiwell, AP | 1 |
| Belluzzi, JD; Leslie, FM; Lotfipour, S; McQuown, SC; Villégier, AS | 1 |
| Panlilio, LV; Schindler, CW; Thorndike, EB | 2 |
| D'Souza, MS; Duvauchelle, CL; Ikegami, A; Olsen, CM | 1 |
| Anderson, MM; Carroll, ME; Morgan, AD; Nelson, SE; Perry, JL | 1 |
| Barot, SK; Ferguson, SM; Neumaier, JF | 1 |
| Dickinson, A; Everitt, BJ; Pelloux, Y | 1 |
| Hu, XT | 1 |
| Dietz, D; Kabbaj, M; Wang, H | 1 |
| Bianchi, E; Cadet, P; Casares, FM; Esch, T; Fricchione, GL; Guarna, M; Kream, RM; Mantione, KJ; Stefano, GB; Zhu, W | 1 |
| Aston-Jones, G; Harris, GC; Hummel, M; Mague, SD; Wimmer, M | 1 |
| Carlezon, WA; Kosofsky, BE; Malanga, CJ; Riday, TT | 1 |
| Liu, X; Slamberová, R; Vathy, I | 1 |
| Cagniard, B; Gu, HH; Han, DD; Tiao, N; Tilley, MR; Zhuang, X | 1 |
| Lu, L; Qiu, Y; Zhai, HF; Zhang, ZY; Zhao, M | 1 |
| Mendez, IA; Setlow, B; Simon, NW | 1 |
| Cherng, CF; Lin, YC; Su, SW; Yu, L | 1 |
| Kantak, KM; Kerstetter, KA | 1 |
| Feltenstein, MW; See, RE | 1 |
| Ferguson, SM; Mitchell, ES; Neumaier, JF | 1 |
| Kosofsky, BE; Malanga, CJ; Pejchal, M | 1 |
| Schoenbaum, G; Shaham, Y; Stalnaker, TA | 1 |
| Ghitza, UE; Lu, L; Qiu, Y; Zhai, HF; Zhang, ZY; Zhao, M | 1 |
| Ahmed, SH; Cantin, L; Lenoir, M; Serre, F | 1 |
| Bahi, A; Dreyer, JL | 1 |
| Hummel, M; Schroeder, JA; Sheikh, R; Simpson, AD; Soderman, AR; Unterwald, EM | 1 |
| Carelli, RM | 1 |
| Akil, H; Flagel, SB; Robinson, TE; Watson, SJ | 1 |
| Dillon, C; Gardner, EL; Gilbert, J; Li, X; Pak, AC; Peng, XQ; Spiller, K; Xi, ZX | 1 |
| Cardon, AL; Diller, AJ; Nation, JR; Rocha, A; Valles, R; Wellman, PJ | 1 |
| Dillon, C; Gardner, EL; Li, SJ; Li, X; Peng, XQ; Spiller, K; Xi, ZX; Yang, Z | 1 |
| Apiou, G; Benturquia, N; Canestrelli, C; Lagente, V; Le Guen, S; Noble, F; Roques, BP | 1 |
| Adinoff, B; Williams, MJ | 1 |
| Bassel-Duby, R; Covington, HE; Graham, A; Haggarty, SJ; Kerstetter, KA; Kippin, TE; Krishnan, V; Kumar, A; Maze, I; McKinsey, TA; Nestler, EJ; Neve, RL; Olson, EN; Renthal, W; Russo, SJ; Tsankova, N; Xiao, G | 1 |
| Hnasko, TS; Palmiter, RD; Sotak, BN | 1 |
| Benavides, DR; Bibb, JA; DiLeone, RJ; Hawasli, AH; Kansy, JW; Olausson, P; Quinn, JJ; Taylor, JR; Yan, Z; Zhong, P | 1 |
| Dell'Orco, JM; Pevzner, A; Robinson, TE; Uslaner, JM | 1 |
| Ashby, CR; Brodie, JD; Dewey, SL; Gardner, EL; Gilbert, JG; Li, X; Pak, AC; Peng, XQ; Xi, ZX | 1 |
| Akhavan, A; Festa, ED; Jenab, S; Luine, V; Minerly, AC; Nazarian, A; Niyomchai, T; Quiñones-Jenab, V; Russo, SJ; Sun, WL; Weierstall, K | 1 |
| Hamid, A; Lutfy, K; Marquez, P; Nguyen, AT | 1 |
| Barnea-Ygael, N; Cooper, A; Levy, D; Shabat-Simon, M; Shalev, U; Zangen, A | 1 |
| Baliram, R; Dabaja, I; Gajawada, N; Lutfy, K; Marquez, P | 1 |
| Antkiewicz-Michaluk, L; Filip, M; Frankowska, M; Gołda, A; Przegaliński, E; Vetulani, J; Zaniewska, M | 1 |
| Ersche, KD; Robbins, TW; Roiser, JP; Sahakian, BJ | 1 |
| Akbarian, S; Jones, SR; Konradi, C; Matevossian, A; Penta, KL; Schroeder, FA; Tapper, AR | 1 |
| Bevins, RA; Reichel, CM | 2 |
| Mashoodh, R; Robertson, HA; Stamp, JA; van Kampen, JM | 1 |
| Katz, JL; Kopajtic, TA; Tanda, G | 1 |
| Nomikos, GG; Panagis, G; Stamatopoulou, F; Vlachou, S | 1 |
| Caba, J; Hernandez, L; Santucci, AC | 1 |
| Michaelides, M; Thanos, PK; Umegaki, H; Volkow, ND | 1 |
| Neisewander, JL; Okun, AC; Thiel, KJ | 1 |
| Soderman, AR; Unterwald, EM | 1 |
| Bohn, MJ; Petry, NM | 1 |
| Hefner, KR; Holmes, A; Karlsson, RM; Sibley, DR | 1 |
| Carlezon, WA; Chartoff, EH; Cohen, BM; Todtenkopf, MS; Tomasiewicz, HC | 1 |
| Arcusa, A; Barcia, JA; Canales, JJ; Ferragud, A; Hernández-Rabaza, V; Hontecillas-Prieto, L; Pérez-Villaba, A; Trejo, JL; Velázquez-Sánchez, C | 1 |
| Bonci, A; Bowers, MS; Carelli, RM; Chen, BT; Chou, JK; Guillory, AM; Hopf, FW; Martin, M | 1 |
| Tomasello, M; Warneken, F | 1 |
| Haines, E; Hernandez, G; Shizgal, P | 1 |
| Wang, B; Wise, RA; You, ZB; Zitzman, D | 1 |
| Brooks, MP; Caster, JM; Kuhn, CM; Schramm-Sapyta, NL; Walker, QD; Waller, ST | 1 |
| Costentin, J; Duterte-Boucher, D; Pelloux, Y | 1 |
| Chandler, LJ; Kalivas, PW | 1 |
| Adamantidis, A; Lakaye, B; Tirelli, E; Tyhon, A | 1 |
| Cowan, CW; Hale, CF; Taniguchi, M | 1 |
| Gu, HH; Han, DD; O'Neill, B; Tilley, MR | 1 |
| Bachtell, RK; Berton, O; Bolanos, CA; DiLeone, RJ; Edwards, S; Gent, LM; Graham, A; Graham, DL; Krishnan, V; Larson, EB; Nestler, EJ; Parada, LF; Self, DW; Simmons, D | 1 |
| Izenwasser, S; Kichko, I; Leoni, G; Zakharova, E | 1 |
| Izenwasser, S; Wade, D; Zakharova, E | 1 |
| Allison, DW; Barber, EN; Horton, ML; Lyle, LT; Steffensen, SC; Stobbs, SH; Taylor, SR | 1 |
| Borrelli, E; De Mei, C; Iitaka, C; Ramos, M | 1 |
| Baumann, MH; Blough, BE; Mello, NK; Negus, SS; Rothman, RB | 1 |
| Gardner, EL; Li, J; Li, X; Peng, XQ; Spiller, K; Xi, ZX | 1 |
| Marron, K | 1 |
| Ettenberg, A; Guzman, D; Moscarello, JM | 1 |
| Abi-Dargham, A; Hwang, DR; Laruelle, M; Liebowitz, MR; Martinez, D; Schneier, FR; Slifstein, M | 1 |
| Carle, T; Carlezon, WA; Dinieri, JA; Gurevich, E; Gurevich, VV; Nemeth, CL; Nestler, EJ; Neve, RL; Parsegian, A | 1 |
| Self, DW; Simmons, D | 1 |
| Barry, D; Petry, NM; Sullivan, B | 1 |
| Barker, PA; Bhakar, AL; Birnbaum, SG; Bolaños, CA; Clark, MS; Dietz, DM; Graham, A; Green, TA; Krishnan, V; Kumar, A; Lesselyong, A; Maze, I; Mazei-Robison, MS; Nestler, EJ; Neumaier, JF; Neve, RL; Perrotti, LI; Renthal, W; Robison, B; Russo, SJ; Wilkinson, MB | 1 |
| Freet, CS; Grigson, PS; Nestler, EJ; Steffen, C | 1 |
| Newland, MC; Reed, MN | 1 |
| Belluzzi, JD; Bonci, A; Chung, S; Civelli, O; Hopf, FW; Li, CY; Nagasaki, H | 1 |
| Cherng, CG; Chiang, CY; Chuang, JY; Ho, MC; Kao, SF; Tsai, YP; Yu, L | 1 |
| Bizon, JL; Gilbert, RJ; Mayse, JD; Setlow, B; Simon, NW | 1 |
| Deadwyler, SA; Hampson, RE; Opris, I | 1 |
| Dembro, KA; Harvey, RC; Kantak, KM; Mutebi, MM; Rajagopalan, K | 1 |
| Bradley, KP; Durgin, A; Laraway, S; Poling, A; Porter, LK | 1 |
| Gardner, EL; Kiyatkin, M; Li, J; Li, X; Peng, XQ; Spiller, K; Wiggins, A; Xi, ZX | 1 |
| Izenwasser, S; Miller, J; Unterwald, E; Wade, D; Zakharova, E | 1 |
| Kelamangalath, L; Seymour, CM; Wagner, JJ | 1 |
| Canales, JJ; Cardá, M; Ferragud, A; Hernández-Rabaza, V; Merino, V; Murga, J; Nácher, A; Velázquez-Sánchez, C | 2 |
| Dezfouli, A; Ekhtiari, H; Keramati, MM; Lucas, C; Mokri, A; Piray, P | 1 |
| Blendy, JA; Briand, L; Cleck, JN; Ecke, L; Kreibich, AS; Rice, KC | 1 |
| Carlezon, WA; Rudolph, U; Straub, CJ | 1 |
| Larson, GA; Nelson, AM; Zahniser, NR | 1 |
| Fowler, JS; Kollins, SH; Logan, J; Ma, Y; Newcorn, JH; Pradhan, K; Swanson, JM; Telang, F; Volkow, ND; Wang, GJ; Wigal, TL; Wong, C; Zhu, W | 1 |
| Fang, J; Grigson, PS; Puhl, MD | 1 |
| Buffalari, DM; See, RE | 1 |
| Undieh, AS; Williams, SN | 1 |
| Faccidomo, S; Fish, EW; Hodge, CW; Malanga, CJ; McGuigan, MM; Riday, TT | 1 |
| Costa, AC; Gregus, AM; Hauck, SC; Inturrisi, CE; Rajadhyaksha, AM; Tropea, TF; Wang, Y | 1 |
| Ashby, CR; Gardner, EL; Li, J; Peng, XQ; Slusher, BS; Thomas, A; Wozniak, K; Xi, ZX | 1 |
| Hiranita, T; Katz, JL; Soto, PL; Tanda, G | 1 |
| Gallo, A; Lapointe, S; Potvin, S; Rompré, PP; Stip, E | 1 |
| De Jesus Quinn, M; Kampman, KM; Lynch, KG; Peoples, L; Plebani, J; Small, AC | 1 |
| Figge, DA; Rademacher, DJ; Sullivan, EM | 1 |
| Colado, MI; Izco, M; Lopez-Jimenez, A; Lopez-Moreno, JA; Mayado, A; O'Shea, E; Peraile, I; Torres, E | 1 |
| Burton, CL; Fletcher, PJ; Nobrega, JN | 1 |
| Burdick, MA; Johnson, ZV; Revis, AA; Rhodes, JS | 1 |
| Covington, HE; Dietz, DM; Greengard, P; Haggarty, SJ; Hurd, YL; LaPlant, Q; Maze, I; Mechanic, M; Mouzon, E; Nestler, EJ; Neve, RL; Ren, Y; Renthal, W; Russo, SJ; Sampath, SC; Schaefer, A; Tarakhovsky, A | 1 |
| Jang, CG; Lee, SY; Nguyen, TL; Oh, S; Yang, CH; You, IJ | 1 |
| Febo, M; Nephew, BC | 1 |
| Atack, JR; Belelli, D; Breen, G; Desrivieres, S; Dixon, CI; Guindalini, C; Jugurnauth, S; King, SL; Lambert, JJ; Laranjeira, R; Messas, G; Morris, HV; Peden, DR; Rosahl, TW; Schumann, G; Steiner, RC; Stephens, DN; Vallada, H | 1 |
| Fernandez-Espejo, E; Moratalla, R; Ortiz, O; Ramiro-Fuentes, S | 1 |
| Ahmed, SH; Cador, M; Darnaudéry, M; Gueye, AB; Vendruscolo, LF | 1 |
| Deadwyler, SA | 1 |
| Brimijoin, S; Gao, Y; Kinsey, B; Kosten, T; Orson, FM | 1 |
| Christensen, CJ; Kearns, DN; Marks, KR; Silberberg, A; Weiss, SJ | 1 |
| Canales, JJ; Cardá, M; Ferragud, A; Murga, J; Velázquez-Sánchez, C | 1 |
| Hironaka, N; Takano, H; Takano, Y; Tanaka, T | 1 |
| Allen, CP; Leri, F | 1 |
| Chavkin, C; Li, S; Schindler, AG | 1 |
| Carta, S; Goldberg, SR; Lecca, S; Luchicchi, A; Muntoni, AL; Pillolla, G; Pistis, M; Yasar, S | 1 |
| Beales, M; Conrad, KL; Cotterly, LM; Ford, KA; Marinelli, M; McCutcheon, JE | 1 |
| Bevins, RA; Reichel, CM; Wilkinson, JL | 1 |
| Angelucci, F; Bernardi, G; Caltagirone, C; Cantarella, C; Castelli, M; Cavasinni, F; Centonze, D; De Chiara, V; Maccarrone, M; Mataluni, G; Musella, A; Napolitano, F; Rossi, S; Sacchetti, L; Usiello, A | 1 |
| Ardecky, R; Conn, PJ; Cosford, ND; Dahl, R; Jin, X; Markou, A; Semenova, S; Sheffler, DJ; Yang, L | 1 |
| Dickson, SL; Egecioglu, E; Engel, JA; Jerlhag, E | 1 |
| Apazoglou, K; Katsidoni, V; Panagis, G | 1 |
| Picciotto, MR | 1 |
| Amelio, AL; Bali, P; Conkright, MD; Hollander, JA; Im, HI; Kenny, PJ; Kocerha, J; Lu, Q; Wahlestedt, C; Willoughby, D | 1 |
| Anderson, BJ; Robison, L; Stamos, J; Thanos, PK; Tucci, A; Volkow, ND; Wang, GJ | 1 |
| Funabiki, K; Hikida, T; Kimura, K; Nakanishi, S; Wada, N | 1 |
| Andersen, SL; Brenhouse, HC; Dumais, K | 1 |
| Foster, R; Gubner, N; Mark, GP; Phillips, TJ; Shabani, S | 1 |
| Bruckmann, W; De Vry, J; Rutten, K; Tzschentke, TM | 1 |
| Harro, J; Kivastik, T; Kõiv, K; Raudkivi, K; Zobel, R | 1 |
| Sanchez, H; Taylor, JR; Torregrossa, MM | 1 |
| Chung, NN; Gibula-Bruzda, E; Izdebski, J; Kotlinska, JH; Kunce, D; Pachuta, A; Schiller, PW; Witkowska, E | 1 |
| Galankin, T; Shekunova, E; Zvartau, E | 1 |
| Fowler, JS; Goldstein, RZ; Klein, N; Kollins, SH; Logan, J; Newcorn, JH; Swanson, JM; Telang, F; Volkow, ND; Wang, GJ; Wigal, TL; Wong, C | 1 |
| Fuchs, RA; Lasseter, HC; Ramirez, DR; Xie, X | 1 |
| Greenwald, MK; Lundahl, LH; Steinmiller, CL | 1 |
| Jiang, W; Liu, JF; Lu, L; Wang, XY; Xue, YX; Yu, LL; Zhou, SJ | 1 |
| Chaudhury, D; Covington, HE; Damez-Werno, D; Deisseroth, K; Dietz, DM; Friedman, AK; Han, MH; Kennedy, PJ; Koo, JW; Lobo, MK; Mogri, M; Mouzon, E; Nestler, EJ; Neve, RL; Sun, H; Zaman, S | 1 |
| España, RA; Jones, SR; Melchior, JR; Roberts, DC | 1 |
| Czoty, PW; Gould, RW; Martelle, JL; Nader, MA | 1 |
| Anker, JJ; Brimijoin, S; Carroll, ME; Gao, Y | 1 |
| Boleij, H; Broekhoven, MH; Cousijn, J; Guitart Masip, M; Snoeren, EM; Spooren, W; Vanderschuren, LJ; Veeneman, MM | 1 |
| Hu, XT; Nasif, FJ; Perez, MF; Ramirez, OA | 1 |
| Ding, ZB; Li, SX; Lu, L; Luo, YX; Shi, HS; Wei, YM; Xue, YX; Yu, CX | 2 |
| Blendy, JA; Cleck, JN; Ecke, LE; Mifflin, L; Schug, J; White, P | 1 |
| Breton, YA; Conover, K; Hernandez, G; Shizgal, P | 1 |
| Anikeeva, P; Brodsky, M; Deisseroth, K; Diester, I; Gradinaru, V; Lin, SC; Prakash, R; Ramakrishnan, C; Witten, IB | 1 |
| Kong, H; Kuang, W; Li, S; Xu, M | 1 |
| Hales, CA; Henehan, RM; Neugebauer, NM; Picciotto, MR | 1 |
| Cami-Kobeci, G; Husbands, SM; Khroyan, TV; Polgar, WE; Toll, L; Zaveri, NT | 1 |
| Brown, AL; Dayas, CV; Flynn, JR; Smith, DW | 1 |
| Blaha, CD; Chesler, EJ; Dickson, PE; Goldowitz, D; Lester, DB; Matta, SG; Miller, MM; Mittleman, G; Rogers, TD | 1 |
| Halbout, B; Heidbreder, C; Hutcheson, DM; Quarta, D; Rigal, A; Valerio, E | 1 |
| Ewan, EE; Martin, TJ | 1 |
| Feng, J; Maze, I; Nestler, EJ; Shen, L; Sun, H; Wilkinson, MB | 1 |
| Halbout, B; Heidbreder, CA; Hutcheson, DM; Quarta, D; Valerio, E | 1 |
| Suto, N; Vezina, P; Wise, RA | 1 |
| Moore, B; Pantalon, MV; Schottenfeld, RS | 1 |
| He, YY; Li, FQ; Li, YQ; Lu, L; Sacktor, TC; Shaham, Y; Xu, CM; Xue, LF; Xue, YX | 1 |
| Aragona, BJ; Cacciapaglia, F; Carelli, RM; Day, JJ; Fuhrmann, KA; Jones, JL; Wheeler, RA; Wightman, RM | 1 |
| Ben-Shahar, O; Ettenberg, A; Haber, ZM; Su, ZI; Waldroup, SA; Wenzel, JM | 1 |
| Gaál, J; Gardner, EL; Li, J; Li, X; Peng, XQ; Song, R; Su, RB; Wu, N; Xi, ZX; Yang, RF | 1 |
| Anderson, KL; Itzhak, Y | 1 |
| Corley, G; Henry, C; Kim, JK; Rasmussen, BA; Rawls, SM; Walker, EA; Ward, SJ | 1 |
| Dobbs, LK; Hansen, ST; Mark, GP; Shabani, S | 1 |
| Markou, A; Stoker, AK | 1 |
| Anastasio, NC; Bubar, MJ; Cunningham, KA; Fox, RG; Gilbertson, SR; Moeller, FG; Rosenzweig-Lipson, S; Stutz, SJ | 1 |
| Gao, S; Nakahara, D; Oki, Y; Suenaga, T; Yukie, M | 1 |
| Ding, ZB; Lu, L; Wu, P; Xu, CM; Xue, LF; Xue, YX | 1 |
| Cabeza de Vaca, S; Carr, KD; Liu, S; Peng, XX; Zheng, D | 1 |
| Grimes, M; Izquierdo, A; Kosheleff, AR; Marshall, JF; O'Dell, SJ | 1 |
| Ion, DI; Lammel, S; Malenka, RC; Roeper, J | 1 |
| Covington, HE; Miczek, KA; Nikulina, EM; Shimamoto, A | 1 |
| Alvarez, VA; Bello, EP; Gelman, DM; Lovinger, DM; Low, MJ; Mateo, Y; Noaín, D; Rubinstein, M; Shin, JH | 1 |
| Kailanto, S; Kankaanpää, A; Seppälä, T | 1 |
| Carlezon, WA; Chartoff, EH; Cohen, BM; Damez-Werno, D; Potter, DN | 1 |
| Aston-Jones, G; Luo, AH; Lupica, CR; Tahsili-Fahadan, P; Wise, RA | 1 |
| Aramini, TC; Bittencourt, LR; Borçoi, AR; Corrêa, JM; Fernandes, HA; Frussa-Filho, R; Fukushiro, DF; Hollais, AW; Kameda, SR; Procópio-Souza, R; Ribeiro, LT; Saito, LP; Santos, R; Talhati, F; Tufik, S; Wuo-Silva, R | 1 |
| Ambrose-Lanci, LM; Berrettini, WH; Bloch, PJ; Clarke, TK; Dackis, CA; Ferraro, TN; Kampman, KM; Lohoff, FW; O'Brien, CP; Oslin, DW; Pettinati, HM | 1 |
| Liu, QS; Pan, B; Sun, D; Zhong, P | 1 |
| Ma, ST; Meyer, PJ; Robinson, TE | 1 |
| Abdalla, M; Ahrens, AM; Duvauchelle, CL; Maier, EY; Schallert, T | 1 |
| Alsiö, J; Arvidsson, E; Birgner, C; Descarries, L; Fortin, GM; Halbout, B; Kullander, K; Lévesque, D; Mahmoudi, S; Nordenankar, K; Olson, L; Smith, C; Trudeau, LÉ; Wallén-Mackenzie, A | 1 |
| Cui, C; Luo, F; Wang, X; Yu, P; Zuo, Y | 1 |
| Bardo, MT; Beckmann, JS; Crooks, PA; Denehy, ED; Dwoskin, LP; Zheng, G | 1 |
| Bushman, BJ; Crocker, J; Moeller, SJ | 1 |
| Carlezon, WA; Muschamp, JW; Nemeth, CL; Nestler, EJ; Robison, AJ | 1 |
| Gesch, J; Giorgetti, F; Heberlein, U; Kharazia, V; Lasek, AW | 1 |
| Baker, LE; Panos, JJ | 1 |
| Kuhn, C; Luo, B; Nicolelis, MA; Oliveira-Maia, AJ; Roberts, CD; Simon, SA; Walker, QD | 1 |
| Broekhoven, MH; Limpens, JH; van Ast, M; Vanderschuren, LJ; Veeneman, MM | 1 |
| Cowhey, KE; Fuchs, RA; Lasseter, HC; Reittinger, AM; Wells, AM; Xie, X | 1 |
| Minogianis, EA; Nachar, W; Samaha, AN | 1 |
| Carrier, N; Dietz, DM; Gaval-Cruz, M; Hollis, F; Kabbaj, M | 1 |
| He, YY; Jiang, WG; Liu, JF; Lu, L; Luo, YX; Wang, XY; Xue, LF; Xue, YX; Zhou, SJ | 1 |
| Edwards, S; Koob, GF; Misra, KK; Park, PE; Schlosburg, JE; Schulteis, G; Vendruscolo, LF; Wee, S | 1 |
| Fish, EW; Jarrett, TM; Malanga, CJ; McGuigan, MM; Riday, TT; Robinson, JE | 1 |
| Markou, A; Olivier, B; Stoker, AK | 1 |
| Glaser, PE; Hays, LR; Lile, JA; Rush, CR; Stoops, WW | 1 |
| Huber, R; Nathaniel, TI; Panksepp, J | 1 |
| Kosofsky, BE; Malanga, CJ; Riday, TT | 1 |
| Matsumoto, RR; McCurdy, CR; Patel, D; Robson, MJ; Rooney, R; Szeszel-Fedorowicz, W; Xu, YT | 1 |
| West, AE | 1 |
| Carreira, MB; Cowan, CW; Neve, RL; Smith, LN; Taniguchi, M; Zirlin, BC | 1 |
| Argento, JK; Arvanitogiannis, A; Flores, C | 1 |
| Burokas, A; Gutiérrez-Cuesta, J; Maldonado, R; Martín-García, E | 1 |
| Foscue, EP; Schramm-Sapyta, NL; Wood, KN | 1 |
| Canestrelli, C; Marie, N; Noble, F | 1 |
| Broos, N; De Vries, TJ; Diergaarde, L; Pattij, T; Schoffelmeer, AN | 1 |
| Ecke, LE; Elmer, GI; Suto, N | 1 |
| Riley, AL; Wetzell, B | 1 |
| Cao, GF; Chen, T; Dang, YH; Zhu, J | 1 |
| Hutchison, MA; Riley, AL | 1 |
| Jenck, F; Lecourt, H; Steiner, MA | 1 |
| Arsenault, JT; Jarraya, B; Mandeville, JB; Marota, JJ; Nelissen, K; Rosen, BR; Vanduffel, W; Wald, LL | 1 |
| España, RA; Ferris, MJ; Harp, J; Jones, SR; Oleson, EB | 1 |
| Jansen, HT; Sergeeva, A; Sorg, BA; Stark, G | 1 |
| Aguilar, MA; Arenas, MC; Daza-Losada, M; Miñarro, J; Rodríguez-Arias, M; Vidal-Infer, A | 2 |
| Arguello, AA; Fuchs, RA; Reittinger, AM; Wells, AM; Xie, X | 1 |
| Alguacil, LF; Cano, V; Del Olmo, N; Fole, A; López, L; Merino, B; Morales, L; Ruggieri, D; Ruiz-Gayo, M; Stucchi, P; Valladolid-Acebes, I | 1 |
| Klug, JR; Kourrich, S; Mayford, M; Thomas, MJ | 1 |
| Friedman, TC; Hamid, A; Kieffer, B; Lutfy, K; Marquez, P; Nguyen, AT | 1 |
| Carroll, ME; Meisel, RL; Regier, PS | 1 |
| Conrad, KL; Davis, AR; Javitch, JA; Lindsley, CW; Matthies, HJ; Saleh, SA; Sen, N; Sheffler, DJ; Shields, AD; Silberman, Y; Winder, DG | 1 |
| Alexander, DN; Grigson, PS; Liang, NC; Nyland, JE | 1 |
| Agoglia, AE; Fish, EW; Krouse, MC; Malanga, CJ; Robinson, JE | 1 |
| Araújo, I; Bober, J; Dietrich, MO; Ferreira, JG; Gao, XB; Horvath, TL; Liu, ZW; Mineur, YS; Picciotto, MR; Souza, DO; Tellez, LA | 1 |
| Izenwasser, S; Matos, J; Stagg, M; Starosciak, AK; Zakharova, E | 1 |
| Carlezon, WA; Engin, E; Lau, HM; Muschamp, JW; Reynolds, LM; Rudolph, U; Tantillo, G | 1 |
| Alaghband, Y; Marshall, JF | 1 |
| Goldstone, AP; Hackenberg, T; Jackson, RN; Jackson, SN; le Roux, CW; Miras, AD; Olbers, T; Spector, AC | 1 |
| Alia-Klein, N; Goldstein, RZ; Maloney, T; Moeller, SJ; Parvaz, MA; Squires, NK; Telang, F; Volkow, ND; Wang, GJ; Woicik, PA | 1 |
| Anagnostou, I; Katsidoni, V; Panagis, G | 1 |
| Conover, K; Cossette, MP; Hernandez, G; Shizgal, P; Trujillo-Pisanty, I | 1 |
| Aragon, CM; Ledesma, JC | 1 |
| Tai, F; Wang, J; Zhang, L; Zhang, P | 1 |
| Beck, KD; Bobzean, SA; Dennis, TS; Dougall, AL; Perrotti, LI | 1 |
| Itoh, T; Mori, T; Rahmadi, M; Shibasaki, M; Suzuki, T; Yoshizawa, K | 1 |
| Béguin, C; Carlezon, WA; Cohen, BM; Potter, DN; Stöhr, T | 1 |
| Bailey, JS; Eisener-Dorman, AF; Grabowski-Boase, L; Huitron-Resendiz, S; Roberts, AJ; Tarantino, LM; Wiltshire, T | 1 |
| Anagnostaras, SG; Cai, DJ; Sage, JR; Shuman, T | 1 |
| Jonkman, S; Kenny, PJ | 1 |
| Barwitz, CM; Dechant, G; Humpel, C; Kummer, KK; Prast, JM; Zernig, G | 1 |
| Ho, A; Kreek, MJ; Kruyer, A; Zhou, Y | 1 |
| Gu, HH; O'Neill, B; Tilley, MR | 1 |
| Robinson, TE; Yager, LM | 1 |
| Dankoski, EC; Fish, EW; Han, JE; Hodge, CW; Krouse, MC; Malanga, CJ; Philpot, BD; Riday, TT; Walsh, PL; Wightman, RM | 1 |
| Araos, P; Bermúdez-Silva, FJ; Bilbao, A; Blanco, E; Fernández-Espejo, E; Luque-Rojas, MJ; Palomino, A; Rodríguez de Fonseca, F; Spanagel, R; Suárez, J; Vida, M | 1 |
| Grigson, PS; Nyland, JE | 1 |
| Chavkin, C; Chavkin, NW; Gustin, RM; Hagan, CE; Lemos, JC; Messinger, DI; Neumaier, JF; Schattauer, SS; Schindler, AG; Shankar, H; Smith, JS | 1 |
| Chen, X; Damaj, MI; Jackson, KJ; Sanjakdar, SS | 1 |
| Bailey, CP; Cordery, SF; Delgado-Charro, MB; Guy, RH; Husbands, SM; Ridzwan, IE; Taverner, A | 1 |
| Febo, M; Johnson, TR; Moulder, JK; Smerkers, B; Stellar, JR | 1 |
| Carlezon, WA; Muschamp, JW | 1 |
| Ding, ZB; Liu, MM; Lu, L; Ren, ZY; Xue, LF; Xue, YX; Zhai, SD | 1 |
| Ahmed, SH; Cantin, L; Lenoir, M; Serre, F; Vanhille, N | 1 |
| Allen, AG; DePoy, LM; Gourley, SL; Noble, B | 1 |
| Cabeza de Vaca, S; Carr, KD; Liu, S; Zheng, D | 1 |
| Frankort, A; Havermans, R; Jansen, A; Roebroeck, A; Roefs, A; Siep, N | 1 |
| Chefer, S; Guillem, K; Kurup, P; Liu, HS; Lu, H; Peoples, L; Rea, W; Stein, EA; Yang, Y | 1 |
| Blendy, JA; Briand, LA | 1 |
| Barch, DM; Luking, KR | 1 |
| Cheer, JF; Myal, S; Oleson, EB; Wang, B; Wise, RA; You, ZB | 1 |
| Adrover, MF; Alvarez, VA; Bock, R; Christensen, CH; Dobi, A; Gremel, CM; Kaplan, AR; Kramer, PF; Markey, E; Shin, JH | 1 |
| Dominguez, JM; Hattori, T; Nutsch, VL; Roma, PG; Tobiansky, DJ; Will, RG | 1 |
| Ettenberg, A; Santoostaroam, A; Su, ZI; Wenzel, J | 1 |
| Glenn, MJ; Helm, SR; St Laurent, R | 1 |
| Huang, B; Liu, X; Ma, L; Yin, XM | 1 |
| Hamon, M; Hervé, D; Lanfumey, L; Molet, J; Thiébot, MH | 1 |
| Ben-Shahar, O; Ettenberg, A; Su, ZI; Wenzel, J | 1 |
| Carelli, RM; West, EA | 1 |
| Boehning, D; Fan, X; Green, TA; Li, D; Pavlovsky, AA; Zhang, Y | 1 |
| LeBlanc, KH; Maidment, NT; Ostlund, SB | 1 |
| Damaj, MI; Ignatowska-Jankowska, BM; Lichtman, AH; Muldoon, PP | 1 |
| Gore, BB; Zweifel, LS | 1 |
| Ahmed, SH; Guillem, K; Vandaele, Y | 1 |
| Belgardt, BF; Brönneke, HS; Brüning, JC; Dietrich, MO; Elemento, O; Franz, T; Hess, ME; Hess, S; Horvath, TL; Jaffrey, SR; Jordan, SD; Kloppenburg, P; Koch, L; Meyer, KD; Rüther, U; Saletore, Y; Verhagen, LA | 1 |
| Bonito-Oliva, A; Cabib, S; Conversi, D; Montanari, C; Orsini, C | 1 |
| Ahmed, SH; Augier, E; Lenoir, M; Vouillac, C | 1 |
| Baunez, C; Cador, M; Lardeux, S; Paleressompoulle, D; Pernaud, R | 1 |
| Arcan, C; Fulkerson, JA; Hannan, PJ; Himes, JH; Rock, BH; Smyth, M; Story, M | 1 |
| Bamba, T; Bando, K; Fukusaki, E; Horie, H; Ishii, A; Katagi, M; Miyawaki, I; Sato, T; Shima, N; Suzuki, K; Tatsuno, M; Tsuchihashi, H; Zaitsu, K | 1 |
| Carey, AN; Gomes, SM; He, JJ; McLaughlin, JP; Paris, JJ; Shay, CF | 1 |
| Colagiuri, B; Lovibond, PF | 1 |
| Robinson, TE; Saunders, BT; Yager, LM | 1 |
| Hokazono, M; Mori, T; Ogawa, Y; Rahmadi, M; Shibasaki, M; Suzuki, T; Wang, TC | 1 |
| Gubner, NR; McKinnon, CS; Phillips, TJ; Reed, C | 1 |
| Bi, GH; Gardner, EL; Keck, TM; Newman, AH; Srivastava, R; Wang, XF; Xi, ZX; Yang, HJ; Zhang, HY; Zou, MF | 1 |
| Belluzzi, JD; Leslie, FM; Mojica, CY | 1 |
| Carelli, RM; Saddoris, MP | 1 |
| Chiu, YT; Huang, P; Lee, DY; Liu-Chen, LY; Ma, Z; Rasakham, K; Unterwald, E; Wang, Y; Xu, W | 1 |
| Gao, Y; Li, Y; Lin, J; Liu, L; Peng, S; Tan, Y; Wen, Q; Zheng, C | 1 |
| Feng, J; Ferguson, D; Heller, E; Heshmati, M; Koo, JW; Liu, X; Nestler, EJ; Neve, R; Rabkin, J; Renthal, W; Sartorelli, V; Shao, N; Shen, L | 1 |
| Kiyatkin, EA; Wakabayashi, KT | 1 |
| Beveridge, TJ; Calipari, ES; Jones, SR; Porrino, LJ | 1 |
| Abbas, Z; Arvanitogiannis, A; Bernstein, DL; Cheer, JF; Gentry, RN; Hernandez, G; Oleson, EB | 1 |
| Bi, GH; Gardner, EL; Li, J; Song, R; Xi, ZX; Yang, RF; Zhang, HY | 1 |
| Caffrey, MK; Febo, M | 1 |
| Shelton, KL; Slavova-Hernandez, GG; Tracy, ME | 1 |
| Diberto, JF; Fish, EW; Krouse, MC; Malanga, CJ; Robinson, JE; Stringfield, SJ | 1 |
| Bachtell, RK; Merritt, KE | 1 |
| Carroll, ME; Hedges, VL; Meisel, RL; Zlebnik, NE | 1 |
| Bisaga, A; Hołuj, M; Popik, P | 1 |
| Martin-Fardon, R; Weiss, F | 2 |
| Bishop, GA; During, MJ; Gu, HH; Han, DD; Hill, ER; O'Neill, B; Thirtamara-Rajamani, K; Tilley, MR; Zhou, FM | 1 |
| Dow-Edwards, D; Iijima, M; Jackson, A; Stephenson, S; Weedon, J | 1 |
| Dixon, CI; Halbout, B; King, SL; Stephens, DN | 1 |
| De La Garza, R; Hamon, SC; Harding, MJ; Kosten, TR; Mahoney, JJ; Newton, TF; Nielsen, DA; Reyes, JA; Spellicy, CJ | 1 |
| Barch, DM; Luby, JL; Luking, KR | 1 |
| Lagorio, CH; Winger, G | 1 |
| Aston-Jones, G; Beckley, JT; Deisseroth, K; Kaufling, J; Keistler, CR; Mahler, SV; McGlinchey, EM; Vazey, EM; Wilson, SP; Woodward, JJ | 1 |
| Ahmed, SH; Madsen, HB | 1 |
| Białko, M; Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E | 1 |
| Baker, DA; Lim, Y; Makky, K; Mantsch, JR; McReynolds, JR; Thao, M; Vranjkovic, O | 1 |
| Ananthan, S; Hachimine, P; Ranaldi, R; Seepersad, N | 1 |
| Borgland, SL; Carlezon, WA; Hassinger, LC; Hollander, JA; Kamenecka, TM; Kenny, PJ; Muschamp, JW; Onvani, S; Thompson, JL; Voren, G | 1 |
| Brown, RM; Kim, JH; Lawrence, AJ; Luikinga, S; Perry, C; Zbukvic, I | 1 |
| Arango-Lievano, M; Bradbury, K; Feliz, A; Gelfand, Y; Greengard, P; Kaplitt, MG; Marongiu, R; Nestler, EJ; Russo, SJ; Schwarz, JT; Vernov, M; Warner-Schmidt, J; Wilkinson, MB | 1 |
| Albein-Urios, N; Civit, E; de la Torre, R; Lozano, O; Martinez-Gonzalez, JM; Verdejo-Garcia, A | 1 |
| Bouayad-Gervais, K; Lévesque, D; Minogianis, EA; Samaha, AN | 1 |
| Bozarth, MA; KuoLee, R; Pudiak, CM | 1 |
| Anschütz, DJ; Buijzen, M; Folkvord, F; Nederkoorn, C; Westerik, H | 1 |
| DiBerto, JF; Fish, EW; Malanga, CJ; Morrow, AL; Robinson, JE; Whitman, BJ | 1 |
| Gu, HH; Han, DD; O'Neill, B; Thirtamara-Rajamani, K; Wang, Y; Wu, H | 1 |
| Aguilar, MA; Arenas, MC; Manzanedo, C; Mateos-García, A; Miñarro, J; Rodriguez-Arias, M; Roger-Sánchez, C | 1 |
| De Sanctis, P; Foxe, JJ; Garavan, H; Morie, KP | 1 |
| Anglard, P; Barbelivien, A; Bodetto, SP; Majchrzak, M; Romieu, P; Sartori, M; Tesone-Coelho, C; Zwiller, J | 1 |
| Chavkin, C; Ehrich, JM; Phillips, PE | 1 |
| Filip, M; Fuxe, K; Gołembiowska, K; Kamińska, K; Suder, A; Wydra, K | 1 |
| Bowers, MS; Brunzell, DH; Damaj, MI; Maldoon, PP; Marks, MJ; Maskos, U; McIntosh, JM; Sanjakdar, SS | 1 |
| Carter, AG; Cassel, JM; MacAskill, AF | 1 |
| Green, CE; Heads, A; Schmitz, JM; Stotts, AL; Suchting, R; Vujanovic, A | 1 |
| Caparelli, EC; Logan, J; Tomasi, D; Volkow, ND; Wang, GJ; Wang, R | 1 |
| Cameron, CM; Carelli, RM; Wightman, RM | 1 |
| Clark, SD; Dietz, DM; Kausch, MA; MacLaren, DA; Markovic, T; Mueller, LE; Park, J | 1 |
| Barr, JL; Unterwald, EM | 1 |
| Chen, YJ; Ma, L; Tao, YZ; Wang, JJ; Yao, WQ | 1 |
| Itzhak, Y; Liddie, S | 1 |
| Bi, GH; Gao, M; Gardner, EL; Li, X; Liu, QR; Wu, J; Xi, ZX; Yang, HJ; Zhang, HY | 1 |
| Svenningsson, P | 1 |
| Arey, RN; Falcon, E; Gillman, AG; Lyons-Weiler, J; McClung, CA; Mukherjee, S; Nugent, AL; Ozburn, AR; Self, DW; Spencer, SM; Twaddle, A | 1 |
| Havermans, RC; Kalamatianos, A; Nederkoorn, C; Vancleef, L | 1 |
| Alexander, DN; Anosike, N; Ballard, SM; Carter, AB; Cox, TA; Freet, CS; Grigson, PS; Imperio, CG; Mahmoud, S; Ruiz-Velasco, V | 1 |
| Li, X; Wolf, ME | 1 |
| Broekhoven, MH; Damsteegt, R; Limpens, JH; Vanderschuren, LJ; Voorn, P | 1 |
| Cuadra, GR; Orsingher, OA; Perondi, MC; Valdomero, A | 1 |
| Amoa, R; Apostolidis, S; Kaster, M; O'Rear, C; Ritz, R; Schmitzer-Torbert, N; Stowers, J | 1 |
| Al-Hassani, HK; Gregg, RA; Grizzanti, D; Haidery, M; Raffa, RB; Ramnath, A; Rawls, SM; Reitz, AB; Smith, GR; Tallarida, CS; Vouga, A | 1 |
| Belzung, C; Castelnau, P; Chalon, S; Cortese, S; Emond, P; Faraone, SV; Galineau, L; Lepelletier, FX; Nicolas, C; Solinas, M; Tauber, C | 1 |
| Benturquia, N; Geoffroy, HA; Noble, F; Puig, S | 1 |
| Kearns, DN; Tunstall, BJ | 1 |
| Clementz, MA; Jablonski, J; McLaughlin, JP; Mediouni, S; Paris, JJ; Thenin-Houssier, S; Valente, ST | 1 |
| Atalayer, D; Haney, RZ; Kambhampati, S; Lucantonio, F; Rowland, NE; Schoenbaum, G; Shaham, Y | 1 |
| Amat, J; Bachtell, RK; Baratta, MV; Cochran, TA; Cooper, DC; Galer, EL; Hiranita, T; Huang, Y; Hutchinson, MR; Katz, JL; Kopajtic, TA; Larson, G; Li, CM; Maier, SF; Northcutt, AL; O'Neill, CE; Pomrenze, MB; Rice, KC; Wang, X; Watkins, LR; Yin, H; Zahniser, NR | 1 |
| Ettenberg, A; Fomenko, V; Kaganovsky, K; Shelton, K; Wenzel, JM | 1 |
| Rawls, SM; Tallarida, CS; Tallarida, RJ | 1 |
| Aguilar, MA; Miñarro, J; Rodríguez-Arias, M; Roger-Sánchez, C | 1 |
| Brosch, T; Delplanque, S; Pool, E; Sander, D | 1 |
| Carelli, RM; Dykstra, LA; Green, JL | 1 |
| Brimijoin, S; Gao, Y; Geng, L; Miller, JD; Murthy, V; Reyes, S; Zhang, B | 1 |
| Cui, C; Li, Y; Ping, X; Yu, P; Zuo, Y | 1 |
| Hauber, W; Mai, B | 1 |
| Grasing, K; He, S; Yang, Y | 1 |
| Aguilar, MA; Arenas, MC; Manzanedo, C; Mateos-García, A; Miñarro, J; Navarro-Francés, CI; Reig-Sanchis, E; Rodríguez-Arias, M; Valverde, O | 1 |
| Perreau-Lenz, S; Spanagel, R | 1 |
| Funabiki, K; Goto, A; Kamioka, Y; Matsuda, M; Nakahara, I; Nakanishi, S; Sumiyama, K; Yamaguchi, T | 1 |
| Baunez, C; Bonneau, N; Cador, M; Cohen, C; Fournier, ML; Hachem-Delaunay, S; Le Moine, C | 1 |
| Aguilar, MA; Maldonado, C; Manzanedo, C; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M | 1 |
| Flores, C; Gifuni, AJ; McCrea, ET; Reynolds, LM; Shizgal, P | 1 |
| Herrmann, ES; Johnson, MW; Johnson, PS; Sweeney, MM | 1 |
| Cahill, CM; Castonguay, A; Cook, C; De Koninck, Y; Evans, CJ; Ghogha, A; Murphy, NP; Olmstead, MC; Taylor, AJ; Taylor, AM; Xue, L | 1 |
| Canales, JJ; Hoener, MC; Mortas, P; Pei, Y | 1 |
| Archbold, J; Febo, M; Girard, L; Hildebrand, DG; McConnell, K; Moffa, A; Morin, K; Pira, AS; Price, K; Radic, M; Reed, MD; Rycyna, L; Santangelo, G; Stellar, JR; Tang, A | 1 |
| Lecca, S; Mameli, M; Meye, FJ; Tchenio, A; Valentinova, K | 1 |
| Arango-Lievano, M; Kaplitt, MG | 1 |
| Boivin, JR; Piscopo, DM; Wilbrecht, L | 1 |
| Rorabaugh, JM; Stratford, JM; Zahniser, NR | 1 |
| Allen, AG; Butkovich, LM; DePoy, LM; Gourley, SL; Shapiro, LP; Swanson, AM | 1 |
| Anderson, LC; Chesler, EJ; Dickson, PE; Hou, L; Long, KH; McNaughton, KA | 1 |
| Arthur, K; Enman, NM; Perrine, SA; Unterwald, EM; Ward, SJ | 1 |
| Ahmed, SH; Cantin, L; Serre, F; Vandaele, Y; Vouillac-Mendoza, C | 1 |
| Erb, S; Ito, R; Nguyen, D; Schumacher, A | 1 |
| Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S | 1 |
| Cahill, CM; Castonguay, A; De Koninck, Y; Evans, CJ; Ghogha, A; Levitt, P; Mehrabani, S; Olmstead, MC; Pradhan, AA; Taylor, AM; Vayssiere, P; Wu, J; Xue, L | 1 |
| Baker, PM; Chartoff, EH; Ebner, SR; Potter, D; Ragozzino, ME; Roitman, MF; Sparrow, A | 1 |
| Liu, QR; Otvos, L; Wang, B; Wise, RA; Wu, Y; You, ZB | 1 |
| Abbott, S; Boyapati, V; Deakin, JF; Elliott, R; Erritzoe, D; Ersche, KD; Faluyi, Y; Faravelli, L; Fernandez-Egea, E; Flechais, RS; Kalk, NJ; Kuchibatla, SS; Lingford-Hughes, AR; McGonigle, J; Metastasio, A; Mick, I; Murphy, A; Nestor, L; Nutt, DJ; Orban, C; Passetti, F; Paterson, LM; Rabiner, EA; Reed, LJ; Robbins, TW; Smith, DG; Suckling, J; Tait, R; Taylor, EM; Waldman, AD | 1 |
| Bostwick, TA; Pomfrey, RL; Riley, AL; Wetzell, BB | 1 |
| Carroll, ME; Holtz, NA; Radke, AK; Zlebnik, NE | 1 |
| Andrews, ZB; Dinan, T; Lawrence, AJ; Lockie, SH; Spencer, SJ | 1 |
| Dechant, G; El Rawas, R; Kummer, KK; Sadangi, C; Salti, A; Saria, A | 1 |
| Bohn, LM; David Leonardo, E; Garcia-Garcia, AL; Gardner, PD; Koob, GF; Tapper, AR; Wee, S; Wright, SR; You, IJ | 1 |
| Eans, SO; Ganno, ML; Hunkele, A; Le Rouzic, V; Majumdar, S; Marrone, GF; McLaughlin, JP; Pasternak, GW; Subrath, JJ; Váradi, A | 1 |
| Cheer, JF; Covey, DP; Lupica, CR; Treadway, T; Wang, H | 1 |
| Labouesse, MA; Langhans, W; Meyer, U | 1 |
| Cruz, B; Iñiguez, SD; Mazei-Robison, MS; Nieto, SJ; Riggs, LM; Robison, AJ; Wright, KN; Zamora, NN; Zavala, AR | 1 |
| Martin-Fardon, R; Matzeu, A; Weiss, F | 1 |
| Cox, CD; Gall, CM; Geschwind, DH; Karsten, CA; Lee, D; Peñagarikano, O; Piomelli, D; Wei, D | 1 |
| Alexander, DN; Boisvert, MM; Grigson, PS; Handly, E; Iyer, P; Nyland, JE; Piquet, AL; Puhl, MD; Rao, A; Subramanian, MP; Subramanian, T; Venkiteswaran, K | 1 |
| Cools, R; De Bruijn, ER; Franke, B; Ramaekers, JG; Spronk, DB; Van der Schaaf, ME; van Wel, JH; Verkes, RJ | 1 |
| Engmann, O; Filhol, O; Gasmi, L; Gervasi, N; Gilligan, D; Giralt, A; Girault, JA; Greengard, P; Hervé, D; Marion-Poll, L; Nairn, AC; Picciotto, MR | 1 |
| Alexander, DN; Grigson, PS; Nyland, JE | 1 |
| Chen, L; Ge, S; Li, N; Li, Y; Wang, J; Wang, X; Wu, H; Zhang, S | 1 |
| Nestler, EJ | 1 |
| Carelli, RM; Saddoris, MP; Sugam, JA; Wang, X | 1 |
| Abraham, AD; Lattal, KM; Neve, KA | 2 |
| Goldberg, SR; Justinova, Z; Makriyannis, A; Redhi, GH; Scherma, M; Schindler, CW; Vadivel, SK | 1 |
| Amano, M; Funahashi, Y; Kaibuchi, K; Kobayashi, K; Kuroda, K; Miura, M; Nagai, T; Nakamuta, S; Nakano, T; Nakauchi, S; Nishi, A; Nishioka, T; Takano, T; Tsuboi, D; Uchigashima, M; Watanabe, M; Yamada, K; Yoshimoto, J; Zhang, X | 1 |
| Alajaji, M; Carroll, FI; Damaj, MI; Kota, D; Lazenka, MF; Levine, A; Selley, DE; Sim-Selley, LJ; Wise, LE; Younis, RM | 1 |
| Li, JX; Liu, JF; Thorn, DA; Zhang, Y | 1 |
| Bagot, RC; Calipari, ES; Davidson, TJ; Deisseroth, K; Guise, KG; Nestler, EJ; Peña, CJ; Pirpinias, ST; Purushothaman, I; Ramakrishnan, C; Walker, DM; Yorgason, JT | 1 |
| de Carvalho, CR; Takahashi, RN | 1 |
| Bagot, RC; Cahill, ME; Cates, HM; Dietz, DM; Feng, J; Gancarz, AM; Heller, EA; Kennedy, PJ; Koo, JW; Nestler, EJ; Neve, RL; Shen, L; Sun, H; Walker, DM; Wang, ZJ | 1 |
| Havermans, RC; Jansen, A; van den Akker, K; van den Broek, M | 1 |
| Daglian, J; Jung, KM; Lee, D; Li, D; Piomelli, D; Wei, D | 1 |
| Aguilar, MA; Manzanedo, C; Miñarro, J; Revert, N; Rodríguez-Arias, M; Roger-Sánchez, C; Vilanova, I | 1 |
| Alvarez, VA | 1 |
| Gourley, SL; Pitts, EG; Taylor, JR | 1 |
| Chan, CL; Wheeler, DS; Wheeler, RA | 1 |
| Avvisati, R; Badiani, A; Contu, L; Michetti, C; Montanari, C; Scattoni, ML; Stendardo, E | 1 |
| Akins, CK; Gill, KE; Prendergast, MA; Reynolds, AR | 1 |
| Cowan, CW; Penrod, RD; Smith, LN; Taniguchi, M | 1 |
| Brimijoin, S; Carroll, ME; Gao, Y; Greer, A; Parks, RJ; Smethells, JR; Swalve, N | 1 |
| Bachtell, RK; Burrow, KR; Cao, JL; Cooper, DC; Fowler, M; Illig, KR; Klipec, WD; Lawyer, CR; O'Neill, C; Ostertag, E | 1 |
| Delis, F; Greengard, P; Grunseich, A; Kane, K; Malave, L; Mangine, P; Thanos, PK; Vitale, M; Volkow, ND | 1 |
| Cherng, CF; Tzeng, WY; Wang, SW; Yu, L | 1 |
| Cannella, LA; Heldt, NA; Lutton, EM; Merkel, SF; Persidsky, Y; Ramirez, SH; Rawls, SM; Razmpour, R; Tallarida, CS | 1 |
| Damez-Werno, DM; Dias, C; Dietz, DM; Gancarz, AM; Koo, JW; Martin, JA; Mouzon, EA; Nestler, EJ; Neve, RL; Rabkin, J; Scobie, KN; Shao, NY; Shen, L; Sun, H; Wang, ZJ; Werner, CT | 1 |
| Burek, DD; Hamilton, PJ; Heller, EA; Lombroso, SI; Nestler, EJ; Neve, RL; Peña, CJ | 1 |
| Chen, Y; Liu, QS; Liu, X; Lu, Y; Penzes, P; Proudfoot, SC; Qi, J; Reynolds, AM; Tong, J | 1 |
| Caffino, L; Fumagalli, F; Giannotti, G; Mottarlini, F; Racagni, G | 1 |
| Wolf, ME | 1 |
| Cheng, G; Liu, C; Wang, J; Zhan, B | 1 |
| Aguilar, MA; Guerri, C; Miñarro, J; Montagud-Romero, S; Montesinos, J; Pascual, M; Rodríguez-Arias, M; Roger-Sanchez, C | 1 |
| Gabbay, V; Goldstein, RZ; Malaker, P; Parvaz, MA | 1 |
| Abin-Carriquiry, JA; Galvalisi, M; Perra, V; Piras, G; Prieto, JP; Scorza, C; Serra, GP; Valentini, V | 1 |
| Barker, AT; Rebec, GV | 1 |
| Bullmore, ET; de Wit, S; Ersche, KD; Gillan, CM; Jones, PS; Luijten, M; Robbins, TW; Sahakian, BJ; Ward, LH; Williams, GB | 1 |
| Carroll, ME; Collins, M; Dougen, B; Johnson, S; Kohl, EA | 1 |
| Borges, S; Coimbra, B; Costa, P; David-Pereira, A; Pinto, L; Rodrigues, AJ; Soares-Cunha, C; Sousa, N | 1 |
| LE, QM; Li, YQ; Ma, L; Wang, FF; Yu, XC | 1 |
| Atlas, D; Filip, M; Frankowska, M; Jastrzębska, J | 1 |
| Aguilar, MA; Guerri, C; Miñarro, J; Montagud-Romero, S; Pascual, M; Reguilon, MD; Rodríguez-Arias, M; Roger-Sanchez, C | 1 |
| Bentzley, BS; Kawa, AB; Robinson, TE | 1 |
| Nelson, KH; Rice, KC; Riley, AL; Woloshchuk, CJ | 1 |
| Rose, EJ; Ross, TJ; Salmeron, BJ; Schweitzer, JB; Stein, EA; Waltz, J | 1 |
| Cosme, CV; Ewald, VA; Gutman, AL; LaLumiere, RT; Worth, WR | 1 |
| Alleva, L; Brabant, C; Charlier, Y; Navacerrada, MES; Tirelli, E | 1 |
| Allen, AG; DePoy, LM; Gourley, SL | 1 |
| Galaj, E; Harding, W; Ranaldi, R | 1 |
| Aguilar, MA; Arenas, MC; Gutiérrez, MS; Manzanares, J; Manzanedo, C; Mateos-García, A; Miñarro, J; Navarrete, F; Rodríguez-Arias, M | 1 |
| Carelli, RM; Saddoris, MP; Sugam, JA | 1 |
| Fitzpatrick, CJ; Morrow, JD | 1 |
| Childress, AR; Franklin, TR; Gawrysiak, M; Jagannathan, K; Kampman, KM; Langleben, DD; Monge, ZA; O'Brien, CP; Regier, PS; Suh, JJ; Teitelman, A; Wang, Z; Wetherill, RR; Young, KA | 1 |
| Bell, GA; Bolaños-Guzmán, CA; Hull, EM; McHenry, JA; Nestler, EJ; Robison, CL; Vialou, VV | 1 |
| Aguilar, MA; Aracil-Fernández, A; Blanco-Gandía, MC; Cantacorps, L; Manzanares, J; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M; Valverde, O | 1 |
| Barker, DJ; Gentile, TA; Gregg, RA; Mo, L; Muschamp, JW; Rawls, SM; Simmons, SJ; Tran, FH; von Weltin, E; Watterson, LR | 1 |
| Gewirtz, JC; Kennedy, BC; Kohli, M; Maertens, JJ; Marell, PS | 1 |
| Jiang, C; Liu, P; Ma, L; Shen, M; Wang, F | 1 |
| Gracia-Rubio, I; Laorden, ML; Martinez-Laorden, E; Milanés, MV; Moscoso-Castro, M; Valverde, O | 1 |
| Freeman, KB; Townsend, EA | 1 |
| Jayanthi, LD; Mannangatti, P; Ramamoorthy, S; Sundaramurthy, S | 1 |
| Ahmed, SH; Guillem, K | 3 |
| Cheong, JH; Choi, MJ; Jang, CG; Kim, HJ; Lee, S; Lee, YS; Seo, JW; Yoon, SS | 1 |
| Cahill, ME; Calipari, ES; Deisseroth, K; Han, MH; Juarez, B; Morel, C; Nestler, EJ; Ramakrishnan, C; Ribeiro, E; Roman-Ortiz, C; Walker, DM | 1 |
| Bass, CE; Bettler, B; Bonci, A; Edwards, NJ; McDevitt, RA; Morales, M; Pignatelli, M; Tejeda, HA; Wu, J; Zhang, S | 1 |
| Mooney, J; Rawls, SM | 1 |
| Blanco-Gandía, MC; Rodríguez-Arias, M | 1 |
| Caffino, L; Fumagalli, F; Giannotti, G; Racagni, G | 1 |
| Akil, H; Flagel, SB; García-Fuster, MJ; Parsegian, A; Watson, SJ | 1 |
| Camarasa, J; Duart-Castells, L; Escubedo, E; López-Arnau, R; Luján, MA; Pubill, D; Valverde, O | 1 |
| Bi, GH; Cao, J; Gardner, EL; He, Y; Newman, AH; Tanda, G; Xi, ZX; Xue, G; Yang, HJ; Zhang, HY | 1 |
| Baunez, C; Pelloux, Y | 1 |
| Barker, DJ; España, RA; Gentile, TA; Muschamp, JW; Shaw, JK; Simmons, SJ | 1 |
| Aguilar, MA; Aracil-Fernández, A; Blanco-Gandía, MC; Manzanares, J; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M | 1 |
| Aguilar, MA; Almela, P; Blanco-Gandia, MC; Laorden, ML; Martínez-Laorden, E; Milanés, MV; Miñarro, J; Montagud-Romero, S; Navarro-Zaragoza, J; Nuñez, C; Rodríguez-Arias, M | 1 |
| Conn, PJ; Dall, C; Dencker, D; Fink-Jensen, A; Molander, AC; Thomsen, M; Weikop, P; Wörtwein, G | 1 |
| Donohoe, M; Fischer, DK; Martinez Rivera, A; Rajadhyaksha, AM; Rice, RC | 1 |
| Bagot, RC; Cahill, ME; Dietz, DM; Gancarz, AM; Lardner, CK; Nestler, EJ; Neve, RL; Walker, DM; Wang, ZJ | 1 |
| Carelli, RM; Hurley, SW; West, EA | 1 |
| Hicks, C; Liu-Chen, LY; Philogene-Khalid, HL; Rawls, SM; Reitz, AB | 1 |
| Cuadra, GR; Gutiérrez, MC; Perondi, MC; Valdomero, A | 1 |
| Bissonette, GB; Burton, AC; Patel, PK; Roesch, MR; Zhao, AC | 1 |
| Dencker, D; Gether, U; Jensen, KL; Runegaard, AH; Wörtwein, G | 1 |
| Cho, BR; Kim, JH; Kim, WY; Kwak, MJ | 1 |
| Accoto, A; Andolina, D; Coassin, A; D'Amato, FR; Di Segni, M; Lizzi, AR; Luchetti, A; Luzi, C; Pascucci, T; Ventura, R | 1 |
| Black, EM; Brodnik, ZD; Clark, MJ; España, RA; Kornsey, KN; Snyder, NW | 1 |
| Baranyi, M; Gagov, H; Kalfin, R; Petkova-Kirova, P; Rakovska, A; Windisch, K | 1 |
| Beiser, T; Kohen, R; Numa, R; Yaka, R | 1 |
| Dasalla, J; Grigson, PS; Jenney, CB | 1 |
| Andrews, AM; Cannella, LA; Lutton, EM; Merkel, SF; Ramirez, SH; Razmpour, R | 1 |
| Bruchas, MR; Gomez, AM | 1 |
| Astur, RS; de Wit, H; Hudd, EC; McQuade, CM; Palmisano, AN | 1 |
| Abboussi, O; Ajonijebu, DC; Daniels, WMU; Mabandla, MV | 1 |
| Baker, DA; Bohn, AT; Ebben, AL; Gasser, PJ; Jasek, IA; Kurtoglu, B; Lovell, ME; Mantsch, JR; Wheeler, DS; Wheeler, RA | 1 |
| Badve, PS; Barson, JR; Bass, CE; Bernstein, DL; España, RA | 1 |
| Albert, R; Desai, N; Gonzalez-Fernandez, G; Hakimian, JK; Mendez, IA; Minasyan, A; Mittal, N; Ostlund, SB; Romaneschi, N; Schallert, T; Walwyn, W | 1 |
| Li, Y; Liu, QS; Liu, X; Vickstrom, CR; Yu, L | 1 |
| Aguilar, MA; Blanco-Gandía, MC; Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M | 1 |
| George, O; Kallupi, M; Martin-Fardon, R; Matzeu, A; Schweitzer, P | 1 |
| Kamii, H; Kaneda, K; Minami, M; Shinohara, F | 1 |
| Dakmak, Z; Galaj, E; Ranaldi, R; Seepersad, N | 1 |
| Antonelli, MC; Pallarés, ME; Pastor, V | 1 |
| Hutchinson, CV; Mohammed Jawad, RA; Prados, J | 1 |
| Datta, U; Martini, M; Sun, W | 1 |
| Almacellas-Barbanoj, A; Homberg, JR; Kaag, AM; Karel, P; Prijn, J; Reneman, L; Verheij, MMM | 1 |
| Certa, B; He, D; Lasek, AW; Satta, R | 1 |
| Cheng, D; He, G; Huang, B; Li, Y; Liu, X; Ma, L | 1 |
| Besnard, A; Caboche, J; Engmann, O; Girault, JA; Hervé, D; Longueville, S; Marion-Poll, L; Valjent, E | 1 |
| Belin, D; Everitt, BJ; Giuliano, C | 1 |
| Gross, JD; Kaski, SW; Schroer, AB; Setola, V; Siderovski, DP; Wix, KA | 1 |
| Bristot, G; Escobar, M; Guimarães, LSP; Ornell, F; Pechansky, F; Scherer, JN; Soares, CM; Von Diemen, L | 1 |
| Casal, L; Huitron-Resendiz, S; Roberts, AJ; Tarantino, LM; Thompson, T | 1 |
| Boutrel, B; de Lecea, L; Halfon, O; Magistretti, PJ; Rossetti, C; Sakurai, T; Steiner, N; Yanagisawa, M | 1 |
| Clavin, BH; Deutsch, D; Figueiredo, A; Haj-Dahmane, S; Hamilton, J; Kaczocha, M; Marion, M; Thanos, PK | 1 |
| Asaoka, Y; Kamii, H; Kaneda, K; Minami, M; Shinohara, F | 1 |
| Edamura, M; Fukuda, A; Furukawa, T; Iwashita, T; Kawasaki, H; Kosugi, I; Murakami, G; Nakahara, D | 1 |
| Bu, Q; Cen, X; Chen, B; Fu, D; Guo, W; Hu, Z; Jiang, L; Liu, B; Shao, X; Tian, J; Zhao, Y; Zhu, R | 1 |
| Almeida, FB; Barros, HMT; Freese, L; Gomez, R; Hansen, AW; Heidrich, N; Moura, DJ; Steffens, L; Steinmetz, A | 1 |
| Bissonette, GB; Blume, EM; Burton, AC; Donnelly, M; Heatley, KC; Hinduja, A; Roesch, MR; Vazquez, D | 1 |
| Becker-Krail, DD; Enwright, JF; Fitzgerald, E; Huang, YH; Kaplan, GN; Logan, RW; McClung, CA; Oliver-Smith, J; Parekh, PK; Shelton, MA; Sundarvelu, P; Waplinger, S; Williams, WP; Yamaguchi, S; Yoshino, J; Zhang, H; Zhu, X | 1 |
| Cen, X; Deng, P; Du, C; Fu, D; Gu, H; Jiang, L; Jiang, W; Kong, J; Li, Y; Long, H; Luo, L; Shao, X; Zhang, B; Zhao, Q; Zhao, Y; Zhu, R | 1 |
| Broberger, C; Fisone, G; Protzmann, J; Spigolon, G; Stagkourakis, S; Williams, P | 1 |
| Cui, Y; Ostlund, SB | 1 |
| Bagot, RC; Cahill, KM; Calipari, ES; Cates, HM; Doyle, MA; Feng, J; Godino, A; Koo, JW; Kronman, HG; Labonté, B; Lardner, CK; Logan, RW; Loh, YE; Lorsch, ZS; Mews, P; Nestler, EJ; Purushothaman, I; Rabkin, J; Ramakrishnan, A; Seney, ML; Shen, L; Walker, DM | 1 |
| Gadhiya, S; Harding, W; Manuszak, M; Ranaldi, R | 1 |
| Bading, H; Baur, K; Bengtson, CP; Bernardi, RE; Hach, A; Spanagel, R | 1 |
| Datta, U; Fan, M; Martini, M; Sun, W | 1 |
| Arenas, MC; Manzanedo, C; Miñarro, J; Montagud-Romero, S; Navarro-Francés, CI | 1 |
| Deyama, S; Domoto, M; Hinoi, E; Kaneda, K; Kaneko, S; Nagayasu, K; Nishitani, N; Sasase, H; Wada, S; Yanagida, J; Zhang, T | 1 |
| Delpire, E; Grueter, BA; Joffe, ME; Turner, BD | 1 |
| D'Souza, MS; Rorabaugh, BR; Rose, MJ; Seeley, SL; Stevens, AA; Stoops, TS | 1 |
| Gether, U; Jensen, KL; Runegaard, AH; Wörtwein, G | 1 |
| Beckmann, JS; Lile, JA; Marks, KR; Rush, CR; Stoops, WW; Strickland, JC | 1 |
| Abumrad, NN; Albaugh, VL; Erreger, K; Flynn, CR; Foster, DJ; Galli, A; Ghose, D; Grueter, BA; Hackett, TA; McGuinness, O; Poe, A; Reddy, IA; Saunders, C; Smith, NK; Turner, B | 1 |
| Bagot, RC; Burek, D; Calipari, ES; Doyle, M; Hamilton, PJ; Han, MH; Heshmati, M; Juarez, B; Kasarskis, A; Koo, JW; Kronman, H; Ku, SM; Lardner, C; Mouzon, E; Nestler, EJ; Neve, RL; Pirpinias, S; Purushothaman, I; Ribeiro, EA; Salery, M; Scarpa, JR; Strat, A | 1 |
| Aguiar, DC; Asth, L; Bastos, JR; Batista, EM; da Silveira, VT; de Oliveira, AC; Del Bel, EA; Finn, DP; Gobira, PH; Gomes, JS; Issy, AC; Moreira, FA; Okine, BN; Oliveira, AC; Ribeiro, FM | 1 |
| Marshall, AT; Ostlund, SB | 1 |
| Krpan, D; Schnall, S | 1 |
| Carelli, RM; Moschak, TM; Wang, X | 1 |
| Ehrlich, S; Hölling, H; Mogwitz, S; Reimelt, C; Roessner, V; Wolff, N | 1 |
| Akumuo, RC; España, RA; Gao, WJ; Li, YC; Yan, CX; Zhang, YX | 1 |
| Graziane, NM; McDevitt, DS | 1 |
| Kiguchi, N; Kishioka, S; Kobayashi, D; Matsuzaki, S; Saika, F | 1 |
| Bechard, AR; Jackson, B; Knackstedt, LA; LaCrosse, A; Namba, MD | 1 |
| Ferrer-Pérez, C; Guardia Carrión, AM; López Gallardo, M; Marco, E; Miñarro, J; Montagud-Romero, S; Pérez-Villalba, A; Rodríguez-Arias, M; Viveros, MP | 1 |
| Borroto-Escuela, DO; Filip, M; Fuxe, K; Wydra, K | 1 |
| Bell, RP; Hobkirk, AL; Huettel, S; Meade, CS; Utevsky, AV | 1 |
| Allain, F; Gueye, AB; Samaha, AN | 1 |
| Gardner, EL; Wang, B; Wise, RA; You, ZB | 1 |
| de Miguel, E; Hyytiä, P; Janhunen, SK; Kaskinoro, J; Korpi, ER; Kuokkanen, K; Lainiola, M; Linden, AM; Myllymäki, M; Paasikoski, N; Vekovischeva, O; Vesajoki, M | 1 |
| Borroto Escuela, DO; Filip, M; Frankowska, M; Fuxe, K; Suder, A; Wydra, K | 1 |
| Ballestín, R; Castro-Zavala, A; Ferrer-Pérez, C; Filarowska, J; Luján, MÁ; Miñarro, J; Rodríguez-Arias, M; Valverde, O | 1 |
| Maiya, R; Messing, RO | 1 |
| Harris, RA; Mayfield, RD | 1 |
| Byrnes, EM; Toorie, AM; Vassoler, FM | 1 |
| Ballestín, R; Ferrer-Pérez, C; Martinez, TE; Miñarro, J; Montagud-Romero, S; Reguilón, MD; Rodríguez-Arias, M | 1 |
| Aguilar, MA; Calpe-López, C; García-Pardo, MP; Miñarro, J | 1 |
| Oliva, I; Wanat, MJ | 1 |
| Adams, WK; Ferland, JN; Hounjet, CD; Hynes, TJ; Lindenbach, D; Phillips, AG; Vonder Haar, C; Winstanley, CA | 1 |
| Bodeen, JL; Cessac, ME; Gereau, GB; Lee, JR; Mason, KL; Miller, DK; Moore, JM; Tapia, MA; Weise, VN; Will, MJ | 1 |
| Marrero-Garcia, Y; Rada, RM; Schoenbaum, G; Stalnaker, TA; Takahashi, YK | 1 |
| Petrauskienė, A; Vaitkevičiūtė, J | 1 |
| Li, SX; Liu, KZ; Wang, CY; Wang, DQ; Wang, XL; Wang, Y | 1 |
| Gautam, R; Janda, KD; Leggio, L; Vendruscolo, LF; Wenthur, CJ; Zhou, B | 1 |
| Ahmed, SH; Vandaele, Y; Vouillac-Mendoza, C | 1 |
| Gopinath, KS; Howell, LL; Maltbie, EA | 1 |
| Coutens, B; Guiard, BP; Jouanjus, E; Lapeyre-Mestre, M; Mouledous, L; Rampon, C; Roussin, A; Stella, M | 1 |
| Garcia, BJ; Glass, JD; Jacobson, DA; Jones, PC; Prosser, RA; Yaw, AM | 1 |
| Hernandez, NS; Schmidt, HD | 1 |
| Alsiö, J; Belin, D; Dalley, JW; Everitt, BJ; Giuliano, C; Jupp, B; Morris, Z; Puaud, M; Robbins, TW; Sabir, A; Sala-Bayo, J; Searle, L; Xia, J; Zhukovsky, P | 1 |
| Camarini, R; Hoffmann, LB; Marcourakis, T; Pautassi, RM; Rae, M; Suarez, A | 1 |
| Abdeen, GN; Alqahtani, AR; le Roux, CW; Miras, AD | 1 |
| Chen, JG; Gao, SQ; He, JG; Hu, ZL; Shen, ZC; Wang, F; Xu, JF; Zhang, H; Zhang, PW; Zhao, HH; Zheng, HL | 1 |
| Busatto, GF; Cunha, PJ; Duran, F; Gonçalves, PD; Lima, DR; Malbergier, A; Melo, CVI; Oliveira, HP; Serpa, MH | 1 |
| Groman, SM | 1 |
| Deyama, S; Hinoi, E; Kaneda, K; Sasase, H; Yanagida, J; Zhang, T | 1 |
| Filip, M; Mizera, J; Niedzielska-Andres, E; Pomierny-Chamioło, L; Sadakierska-Chudy, A | 1 |
| Bernardi, RE; Brambilla, R; Fasano, S; Morella, I; Olevska, A; Santos, E; Spanagel, R | 1 |
| Filion, MP; Minogianis, EA; Samaha, AN; Servonnet, A | 1 |
| Anderson, EM; Gomez, D; Hearing, MC; Ingebretson, AE; Madayag, AC; Thomas, MJ | 1 |
| Al-Hasani, R; Bruchas, MR; Dougherty, JD; Maloney, SE; Rieger, MA; Wozniak, DF | 1 |
| Adams, J; Bagley, JR; Bozadjian, RV; Bubalo, L; Kippin, TE | 1 |
| Bertaso, F; Castell, L; Castro, L; Gangarossa, G; Tarot, P; Valjent, E; Veyrunes, F; Vincent, P | 1 |
| Alhadeff, AL; Betley, JN; Goldstein, N; Klima, ML; Park, O; Vargas, A | 1 |
| Abtahi, S; Bastacky, JMR; Currie, PJ; Dunn, DP; Gray, CC | 1 |
| Badiani, A; Caprioli, D; De Pirro, S | 1 |
| Barr, JL; Shi, X; Unterwald, EM; von Weltin, E | 1 |
| Denny, RR; Unterwald, EM | 1 |
| Bi, GH; Galaj, E; Xi, ZX; Yang, HJ | 1 |
| Caron, MG; Karne, SL; Liles, LC; Paladini, CA; Petko, AK; Porter-Stransky, KA; Urs, NM; Weinshenker, D | 1 |
| Ballestín, R; Blanco-Gandia, MC; Guerri, C; Miñarro, J; Montagud-Romero, S; Montesinos, J; Pavón, FJ; Rodríguez de Fonseca, F; Rodríguez-Arias, M | 1 |
| Alalawi, A; Aldhafiri, A; Dodu, JC; Emadzadeh, N; Soderstrom, K | 1 |
| Brady, LJ; Calipari, ES; Hofford, RS; Kiraly, DD; Tat, J | 1 |
| Aguinaga, D; Casanovas, M; Franco, R; Navarro, G; Reyes-Resina, I; Rivas-Santisteban, R | 1 |
| Ávila-Gámiz, F; Castilla-Ortega, E; Moreno Fernández, RD; Sampedro-Piquero, P; Santín, LJ | 1 |
| Davis, RG; Fellers, RT; Goo, YA; Greer, JB; Kelleher, NL; Lasek, AW; LeDuc, RD; Park, HM; Patrie, SM; Romanova, EV; Rubakhin, SS; Satta, R; Sweedler, JV; Tai, R; Thomas, PM | 1 |
| Nawarawong, NN; Olsen, CM | 1 |
| Clasen, MM; Davidson, TL; Kearns, DN; Riley, AL; Sanon, TV | 1 |
| Betzhold, SM; Bizon, JL; Blaes, SL; Dragone, RJ; Finner, AM; Orsini, CA; Setlow, B | 1 |
| Crissman, ME; Nelson, KH; Pescatore, KA; Riley, AL | 1 |
| Andrews, AM; Cannella, LA; Corbett, CB; Kahn, J; McGary, H; Ramirez, SH; Razmpour, R | 1 |
| Cantacorps, L; Luján, MÁ; Montagud-Romero, S; Valverde, O | 1 |
| Donate, MM; Lefner, MJ; Oliva, I; Wanat, MJ | 1 |
| Lane, AE; Lane, DA; Qian, L; Trubetckaia, O; Zhou, P | 1 |
| Burton, AC; Pribut, HJ; Roesch, MR; Tennyson, SS; Vázquez, D | 1 |
| Cheong, JH; Choi, MJ; Jang, CG; Jang, EY; Ka, M; Kim, HJ; Kim, JS; Kim, WH; Lee, YE; Lee, YS; Ryu, IS; Seo, JW; Steffensen, SC; Woo, DH; Yoon, SS | 1 |
| Ahammad, RU; Amano, M; Ariza, A; Emi, R; Funahashi, Y; Kaibuchi, K; Kozawa, S; Kuroda, K; Nagai, T; Shan, W; Suzuki, K; Takano, T; Wu, M; Xu, Y; Yamada, K; Yura, Y | 1 |
| Fullerton, EI; Hildebrant, PC; Judd, JM; Lever, JR; Lever, SZ; Miller, DK; Sage, AS; Tapia, MA; Will, MJ | 1 |
| Bernat, N; Inbar, D; Inbar, K; Kupchik, YM; Levi, LA; Odesser, T | 1 |
| Bailey, L; Chesler, EJ; de Villena, FP; Dickson, PE; Farrington, J; Gagnon, LH; Gaines, CH; Gómez-A, A; Jentsch, JD; Khan, S; Kim, SM; Kumar, P; Leonardo, MR; Logan, RW; McClung, CA; Neira, S; Olson, AA; Philip, VM; Riker, KD; Robinson, DL; Roy, TA; Schoenrock, SA; Tarantino, LM; Valdar, W; Wilcox, TD | 1 |
| Chen, M; Chen, P; Gao, Y; Li, Y; Ren, W; Ruan, J; Zhang, X; Zhu, S | 1 |
| Ahmadi-Soleimani, SM; Azadi, M; Azizi, H; Halliwell, RF; Pachenari, N; Rubino, T; Salmanzadeh, H | 1 |
| Cano, M; Gad, M; Green, KN; Leslie, FM; Linker, KE; Tawadrous, P; Wood, MA | 1 |
| Denomme, WJ; Shane, MS | 1 |
| Amaral, IM; Dechant, G; El Rawas, R; Fontebasso, V; Hofer, A; Lemos, C; Salti, A; Singewald, N | 1 |
| Deyama, S; Domoto, M; Hinoi, E; Kamii, H; Kaneda, K; Kaneko, S; Li, X; Minami, M; Nagayasu, K; Nishitani, N; Sasase, H; Wada, S; Yamanaka, A; Yanagida, J; Zhang, T | 1 |
| Blanco-Gandía, MDC; Miñarro López, J; Ródenas-González, F; Rodriguez-Arias, M | 1 |
| Arenivar, MA; Castillo, SA; Flores-Ramirez, FJ; Garcia-Carachure, I; Iñiguez, SD; Lobo, MK; Preciado-Piña, J; Themann, A; Zavala, AR | 1 |
| Buch, S; Burkovetskaya, ME; Guo, L; Guo, ML; Small, R | 1 |
| Ambrosio, E; Borcel, É; Higuera-Matas, A; Santos-Toscano, R; Ucha, M | 1 |
| Ferrer-Pérez, C; Miñarro, J; Reguilón, MD; Rodríguez-Arias, M | 1 |
| Ben-Ezra, A; Dunn, A; Erazo, J; Kreek, MJ; Morochnik, M; Pikus, P; Reed, B; Windisch, K | 1 |
| Filip, M; Frankowska, M; Gawlińska, K; Gawliński, D | 1 |
| Berridge, KC; Naffziger, EE; Warlow, SM | 1 |
| Baskin, BM; Dymecki, SM; Kantak, KM; Mai, JJ | 1 |
| Alnouti, Y; Buch, S; Burkovetskaya, ME; Gautam, N; Guo, M; Hopkins, CR; Kumar, S; Liu, Q; Miczek, K; Vadukoot, AK | 1 |
| Frankowska, M; Gamberini, S; Gawlińska, K; Gawliński, D; Jastrzębska, J; Pieniążek, R; Suder, A; Wydra, K | 1 |
| Bastle, RM; Dell'Orco, M; Neisewander, JL; Perrone-Bizzozero, NI; Powell, GL; Vannan, A; Wilson, MA | 1 |
| Cann, C; Hope, BT; Ramsey, LA; Venniro, M | 1 |
| Bingor, A; Haham, T; Stern-Bach, Y; Thornton, C; Yaka, R | 1 |
| Ashwal-Fluss, R; Bleistein, N; Citri, A; Del Mar Reus-Garcia, M; Gonzales, BJ; Groysman, M; Mukherjee, D; Peretz-Rivlin, N; Terem, A | 1 |
| Abreu, K; Adams, R; Brown, AN; Chitaman, JM; Feng, J; Hedinger, RL; Kaplan, GJ; Liu, X; Nestler, EJ; Neve, R; Shen, L; Stockman, V; Waddell, NJ; Wang, Z; Xu, H | 1 |
| Ahmed, SH; Canchy, L; Durand, A; Girardeau, P; Vouillac-Mendoza, C | 1 |
| Bi, GH; Cao, J; He, Y; Jordan, CJ; Newman, AH; Xi, ZX; You, ZB | 1 |
| Dhingra, I; Le, TM; Li, CR; Wang, W; Zhang, S; Zhornitsky, S | 1 |
| Samaha, AN | 1 |
| Crissman, ME; Hempel, BJ; Imanalieva, A; Melkumyan, M; Riley, AL; Winston, CA | 1 |
| Baldi, P; Borrelli, E; Brami-Cherrier, K; Cervantes, M; Lewis, RG; Liu, Y; Sassone-Corsi, P; Tognini, P | 1 |
| Doyle, MA; Fejes-Tóth, G; Mazei-Robison, MS; Náray-Fejes-Tóth, A; Stark, AR | 1 |
| Engeln, M; Fox, ME; Lobo, MK | 1 |
| Bobadilla, AC; Dereschewitz, E; Heinsbroek, JA; Kalivas, PW; Scofield, MD; Vaccaro, L | 1 |
| Chaouloff, F; Georges, F; Hurel, I; Marsicano, G; Medrano, MC; Melis, M; Mesguich, E; Redon, B; Stevens, C | 1 |
| Chesworth, R; Karl, T | 1 |
| Blanco-Gandía, MC; Guerri, C; Miñarro, J; Montagud-Romero, S; Pascual, M; Reguilón, MD; Rodríguez-Arias, M | 1 |
| Blakely, RD; Grumbar, GJ; Hahn, MK; Iwamoto, H; Li, Y; Mayer, FP; Stewart, A | 1 |
| Aranäs, C; Jerlhag, E; Kalafateli, AL | 1 |
| Chao, YS; Eid, M; Jhou, TC; Li, H; Pullmann, D; Thomas, AA | 1 |
| Mueller, LE; Schoenbaum, G; Sharpe, MJ; Stalnaker, TA; Wikenheiser, AM | 1 |
| Anastasio, NC; Bjork, JM; Cunningham, KA; Moeller, FG; Nigam, KB; Sami, A; Straub, LK; Zuniga, EA | 1 |
| Chu, J; Deyama, S; Esaki, H; Kaneda, K; Li, X; Motono, M; Nishitani, N; Otoda, A; Saito, A | 1 |
| Amaral, IM; Cera, I; Dechant, G; El Rawas, R; Hofer, A; Lemos, C | 1 |
| Crummy, EA; Ferguson, SM; Garcia, AF; Nooney, MN; Webb, IG | 1 |
| Green, TA; Gupta, NS; Koshy, S; Marmol-Contreras, Y; McAuley, RJ; Vasquez, TES | 1 |
| Chang, Y; Galaj, E; Haishui, S; Jiaqi, L; Li, S; Rulan, D; Wenshuya, L; Xi, Y; Xiaorui, S; Yan, Z; Yipu, Z; Yixiao, L; Yuan, G; Zhenbang, Y | 1 |
| Caffino, L; Cervo, L; Di Clemente, A; Fumagalli, F; Giannotti, G; Moro, F; Mottarlini, F; Orrù, A; Targa, G; Toia, M | 1 |
| Dong, H; He, C; Hong, JH; Huang, M; Kim, YJ; Kong, Q; Kuramoto, K; Levine, B; Meltzer, HY; Miller, RJ; Qiu, X; Wang, N; Xiao, T; Xu, M; Yamamoto, S; Zhao, Y | 1 |
| Kong, Q; Li, Y; Wu, X; Xu, M; Yue, J | 1 |
| Grad, E; Thornton, C; Yaka, R | 1 |
| Khayat, A; Weitz, M; Yaka, R | 1 |
| Almeida-Pereira, G; Haddock, CJ; Harada, CM; Hayes, MR; Kolar, GR; Salvemini, D; Samson, WK; Stein, LM; Yosten, GLC | 1 |
| Blanco-Gandía, MDC; Guerri, C; López, JM; Molari, I; Pascual, M; Ródenas-González, F; Rodríguez-Arias, M | 1 |
| Befort, K; Bourdy, R; De Sa Nogueira, D; Filliol, D; Romieu, P | 1 |
| Cirino, TJ; McLaughlin, JP | 1 |
| Brockett, AT; Pribut, HJ; Roesch, MR; Tennyson, SS; Vázquez, D; Wei, AD | 1 |
| Bagot, RC; Cates, HM; Cunningham, AM; Lipschultz, AP; Nestler, EJ; Ramakrishnan, A; Shen, L; Walker, DM; Zhang, B; Zhou, X | 1 |
| Bjorness, TE; Greene, RW | 1 |
| Bartsch, D; Bernardi, RE; Enkel, T; Pohořalá, V; Spanagel, R | 1 |
| Bills, KB; Chang, S; Fan, Y; Kim, HY; Kim, SC; Lee, BH; Lee, SM; Ryu, Y; Steffensen, SC; Yang, CH | 1 |
| Datta, P; De Freitas, B; Guss, H; Honma, P; Jain, A; Li, Y; Lilascharoen, V; Lim, BK; Okamoto, A; Pate, S; Pribiag, H; Shin, S; Sun, F; Wang, EH; Wang, XY | 1 |
| Ayvazian, VM; Beebe, EJ; Cheer, JF; Cruz, FC; Engi, SA; Wenzel, JM; Zlebnik, NE | 1 |
| Bickel, WK; McClure, SM; Snider, SE; Turner, JK | 1 |
| Campbell, RR; Lobo, MK | 1 |
| Kim, HY; Lee, BH; Yang, CH; Yoon, SS; Yun, J | 1 |
| Gobira, PH; Joca, SR; Roncalho, AL; Sales, AJ; Silote, GP; Silva, NR | 1 |
| Ballestín, R; Colado, MI; Ferrer-Pérez, C; Gil de Biedma-Elduayen, L; Giménez-Gómez, P; Miñarro, J; O'Shea, E; Reguilón, MD; Rodríguez-Arias, M; Vidal, R | 1 |
| Epstein, DH; Panlilio, LV; Shaham, Y; Venniro, M | 1 |
| Carrette, LL; de Guglielmo, G; George, O; Sedighim, S; Shaham, Y; Venniro, M | 1 |
| Gil-Miravet, I; Guarque-Chabrera, J; Melchor-Eixea, I; Miquel, M; Olucha-Bordonau, F | 1 |
| Carpenter, MD; Fischer, DK; Garcia, BA; Hamilton, PJ; Heller, EA; Lim, CJ; Lombroso, SI; Marchione, DM; Neve, RL; Pierce, RC; Wimmer, ME; Xu, SJ | 1 |
| Bali, P; Kenny, PJ | 1 |
| Ahmed, SH; Vandaele, Y | 1 |
| Broderick, MR; Ellis, AL; Horchar, MJ; Kappesser, JL; Wright, MR; Yates, JR | 1 |
| Kawahara, H; Kawahara, Y; Nishi, A; Ohnishi, YH; Ohnishi, YN | 1 |
| Miñarro, J; Montagud-Romero, S; Rodríguez-Arias, M | 1 |
| Kramvis, I; Mansvelder, HD; Matos, MR; Mitrić, MM; Smit, AB; van den Oever, MC; van der Loo, RJ; Visser, E | 1 |
| Fink-Jensen, A; Gainetdinov, RR; Gether, U; Herborg, F; Leo, D; Lilja, JH; Lycas, MD; Rickhag, M; Ridderstrøm, PH; Rifes, P; Sørensen, G; Weikop, P; Woldbye, D; Wörtwein, G | 1 |
| Almeida, FB; Barros, HMT; Costa, PA; de Siqueira Umpierrez, L; de Souza, MF; Fernandes, PR; Freese, L; Nin, MS | 1 |
| Ding, XY; Han, X; Jing, MY; Li, J; Luo, MM; Song, R; Wu, N; Zhao, TY | 1 |
| Chalhoub, RM; Kalivas, PW; Nall, RW | 1 |
| Betzhold, SM; Blaes, SL; Orsini, CA; Setlow, B; Shimp, KG | 1 |
| Pribut, HJ; Roesch, MR; Sciarillo, XA | 1 |
| Burnell, K; De, A; Grasing, KW | 1 |
| Blanco-Gandía, MC; Miñarro, J; Ródenas-González, F; Rodríguez-Arias, M | 1 |
| Baumgartner, HM; Berridge, KC; Granillo, M; Schulkin, J | 1 |
| Beiser, T; Mechoulam, R; Nemirovski, A; Shahen-Zoabi, S; Smoum, R; Yaka, R | 1 |
| Ballestín, R; Miñarro, J; Reguilón, MD; Rodríguez-Arias, M | 1 |
| Casby, J; Groman, SM; Villiamma, P | 1 |
| Calarco, CA; Chandra, R; Choi, EY; Engeln, M; Fox, ME; Herman, RJ; Lobo, MK; Nam, H; Qadir, H; Rhodes, VM; Thomas, SS; Turner, MD | 1 |
| Crook, C; de Guglielmo, G; Iemolo, A; Martinez, A; Montilla-Perez, P; Nur, A; Roberts, A; Telese, F; Turner, A | 1 |
| Adeniran, CA; Ananthan, S; Augelli-Szafran, CE; Cirino, TJ; Deliscar, LS; Eans, SO; Hammond, HR; Jiménez-Torres, AC; McLaughlin, JP; Moukha-Chafiq, O; Nguyen, TH; O'Hara, P; Ofori, E; Patel, P; Quizon, PM; Saini, SK; Strauss, MJ; Vekariya, RH; Wang, Y; Zhan, CG; Zhang, S; Zhu, J | 1 |
| Alvarez, VA; Blegen, MB; Bocarsly, ME; Choi, IB; Dai, KZ; Dobbs, LK; Kaplan, AR; Kellendonk, C; Levitt, R; Matsui, A; Shin, JH; Simpson, EH | 1 |
| Bagot, RC; Browne, CJ; Cates, HM; Cunningham, AM; Godino, A; Hodes, GE; Issler, O; Kennedy, PJ; Lardner, CK; Lipschultz, AP; Nestler, EJ; Parise, EM; Peña, CJ; Ramakrishnan, A; Shen, L; Torres-Berrio, A; Van der Zee, Y; Walker, DM; Zhang, B; Zhou, X | 1 |
| Bagley, JR; Bailey, LS; Chesler, EJ; Jentsch, JD; Karkhanis, A; Tarantino, LM; Wherry, JD | 1 |
| Bills, KB; Fan, Y; Jang, HB; Kim, HY; Kim, SC; Lee, BH; Lee, SM; Steffensen, SC | 1 |
| Ahmed, SH; Guillem, K; Lenoir, M; Navailles, S; Vandaele, Y; Vouillac-Mendoza, C | 1 |
| Aston-Jones, G; Moorman, DE | 1 |
| Bednarska-Makaruk, M; Gawryluk, A; Kołosowska, K; Lehner, M; Liguz-Lęcznar, M; Maciejak, P; Skórzewska, A; Sobolewska, A; Tomczuk, F; Turzyńska, D; Wisłowska-Stanek, A | 1 |
| Baraban, JM; Chen, J; Chen, KH; Liu, Y; Qiu, Z; Yang, J | 1 |
| Beroun, A; Bijoch, Ł; Kaczmarek, L; Klos, J; Legutko, D; Pawłowska, M; Szachowicz, U; Wiśniewska, J | 1 |
| de Fonseca, FR; González-Portilla, M; Montagud-Romero, S; Moya, M; Orio, L; Rodríguez-Arias, M | 1 |
| Dreyer, JK; Ejdrup, AL; Gether, U; Herborg, F; Jørgensen, SH; Lycas, MD; Madsen, KL; Posselt, LP; Sørensen, AT; Tian, L | 1 |
| Brunty, S; Dickson, PE; Huffman, J; Leonardo, M; Lester, DB | 1 |
| Browne, CJ; Durand-de Cuttoli, R; Estill, MS; Futamura, R; Godino, A; Hamilton, PJ; Holt, LM; Mews, P; Nestler, EJ; Neve, RL; Russo, SJ; Salery, M; Shen, L | 1 |
| Cheong, JH; Custodio, RJP; Kim, HJ; Kim, M; Lee, CH; Lee, HJ; Lee, YS; Ortiz, DM; Sayson, LV | 1 |
| Ahluwahlia, A; Dios, C; Green, CE; Holden, C; Hoots, JK; Lane, SD; Miloslavich, K; Nunez, C; Schmitz, JM; Wardle, MC | 1 |
| Aguilar, MA; Calpe-López, C; García-Pardo, MP; Martínez-Caballero, MÁ | 1 |
| Barbee, BR; Butkovich, LM; Davies, RA; Garcia-Sifuentes, Y; Gourley, SL | 1 |
| Butelman, ER; Ewald, A; Kivell, BM; Kornberger, L; McElroy, BD; Prisinzano, TE; van de Wetering, R; Welsh, S; Williamson, SE | 1 |
| Dalto, JF; Medina, JH; Pastor, V | 1 |
| Bingor, A; Grad, E; Mechoulam, R; Nemirovski, A; Shahen-Zoabi, S; Shekh-Ahmad, T; Smoum, R; Yaka, R | 1 |
| Qiu, Z; Yang, J | 1 |
| Asokan, M; Choi, IB; Dobbs, LK; Le, NN; Matsumura, K; Natividad, LA; Nicot, A | 1 |
| Del Bel, E; Gobira, PH; Gomes, FV; Guimarães, FS; Pedrazzi, JFC; Sales, AJ; Silveira, JR | 1 |
| Chujo, Y; Deyama, S; Kaneda, K; Murata, H; Nagasaki, J; Niitani, K; Nishitani, N; Otoda, A; Saito, A; Yanagida, J | 1 |
| Dong, Y; He, Y; Huang, YH; Schlüter, OM | 1 |
60 review(s) available for cocaine and s,n,n'-tripropylthiocarbamate
| Article | Year |
|---|---|
Common intracellular actions of chronic morphine and cocaine in dopaminergic brain reward regions.
Topics: Animals; Brain; Cocaine; Cyclic AMP; GTP-Binding Proteins; Limbic System; Locus Coeruleus; Morphine; Rats; Rats, Inbred Strains; Reward; Tyrosine 3-Monooxygenase | 1992 |
The basic neurobiology of addiction.
Topics: Blood-Brain Barrier; Brain; Cocaine; Humans; Reward; Substance-Related Disorders | 1992 |
Self-stimulation and drug reward mechanisms.
Topics: Animals; Brain; Cocaine; Humans; Nicotine; Phencyclidine; Reward; Self Stimulation; Substance-Related Disorders | 1992 |
Opioid involvement in the rewarding effects of chronic cocaine.
Topics: Animals; Cocaine; Humans; Receptors, Opioid; Reward | 1990 |
The dopamine hypothesis of the reinforcing properties of cocaine.
Topics: Amphetamine; Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Euphoria; Humans; Limbic System; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Protein Binding; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders | 1991 |
New concepts in cocaine addiction: the dopamine depletion hypothesis.
Topics: Animals; Brain; Cocaine; Conditioning, Operant; Dopamine; Euphoria; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mice; Models, Neurological; Models, Psychological; Prolactin; Rats; Reward; Serotonin; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission; Thyroid Gland; Thyrotropin-Releasing Hormone | 1985 |
Chronic neuropharmacology of cocaine: progress in pharmacotherapy.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Humans; Methylphenidate; Psychotherapy; Reward; Self Stimulation; Substance Withdrawal Syndrome; Substance-Related Disorders | 1988 |
Pharmacological approaches to cocaine addiction.
Topics: Brain Chemistry; Bromocriptine; Cocaine; Desipramine; Dopamine; Euphoria; Humans; Receptors, Dopamine; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders; Tyrosine | 1985 |
Neural mechanisms of the reinforcing action of cocaine.
Topics: Amphetamine; Animals; Brain; Cocaine; Food; Humans; Narcotics; Receptors, Dopamine; Reinforcement, Psychology; Reward; Substance-Related Disorders; Water | 1984 |
Dopamine, a common substrate for the rewarding effects of brain stimulation reward, cocaine, and morphine.
Topics: Animals; Brain; Cocaine; Dopamine Uptake Inhibitors; Humans; Morphine; Narcotics; Psychomotor Performance; Reward; Stimulation, Chemical | 1994 |
Cocaine reward and cocaine craving: the role of dopamine in perspective.
Topics: Animals; Brain; Cocaine; Dopamine; Dopamine Agonists; Humans; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Neuropharmacological mechanisms of drug reward: beyond dopamine in the nucleus accumbens.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Humans; Narcotics; Nucleus Accumbens; Reward; Substance-Related Disorders | 1998 |
Stimulant preexposure sensitizes rats and humans to the rewarding effects of cocaine.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Humans; Narcotics; Rats; Reward | 1998 |
Mechanisms of action of drugs of abuse on the developing fetal brain.
Topics: Alcoholism; Animals; Brain; Child; Child Development; Child Rearing; Cocaine; Cocaine-Related Disorders; Confounding Factors, Epidemiologic; Disease Models, Animal; Ethanol; Female; Fetus; Humans; Illicit Drugs; Narcotics; Nutritional Physiological Phenomena; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Reinforcement, Psychology; Reward; Substance-Related Disorders | 1999 |
Mesolimbic neuronal activity across behavioral states.
Topics: Amygdala; Animals; Behavior, Animal; Brain; Cocaine; Limbic System; Neostriatum; Neurons; Prefrontal Cortex; Rats; Reward; Self Administration | 1999 |
Functional magnetic resonance imaging of brain reward circuitry in the human.
Topics: Animals; Brain; Brain Mapping; Cocaine; Cocaine-Related Disorders; Cognition; Humans; Magnetic Resonance Imaging; Male; Nerve Net; Reward | 1999 |
Gamma-hydroxybutyric acid: an evaluation of its rewarding properties in rats and mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Hydroxybutyrates; Injections, Intravenous; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders | 2000 |
Activity patterns in mesolimbic regions in rats during operant tasks for reward.
Topics: Action Potentials; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agonists; Electrodes, Implanted; Ethanol; Haplorhini; Heroin; Limbic System; Models, Neurological; Nicotine; Nucleus Accumbens; Prefrontal Cortex; Psychomotor Performance; Rats; Reward; Species Specificity; Time Factors | 2000 |
Cocaine dependence: a disease of the brain's reward centers.
Topics: Brain; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Disruptive, Impulse Control, and Conduct Disorders; Dopamine Uptake Inhibitors; Humans; Limbic System; Models, Neurological; Psychotherapy; Reward | 2001 |
Cocaine, reward, movement and monoamine transporters.
Topics: Animals; Brain; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Genetic Predisposition to Disease; Genetic Variation; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Mice, Knockout; Models, Neurological; Models, Psychological; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 2002 |
Sigma(1) (sigma(1)) receptor antagonists represent a new strategy against cocaine addiction and toxicity.
Topics: Animals; Brain Stem; Calcium; Cocaine; Cocaine-Related Disorders; Dopamine; Excitatory Amino Acid Antagonists; Humans; Limbic System; Models, Animal; Narcotics; Radioligand Assay; Receptors, Dopamine; Receptors, Serotonin; Receptors, sigma; Reinforcement, Psychology; Reward; Self Administration; Sigma-1 Receptor | 2002 |
Reward, memory and substance abuse: functional neuronal circuits in the nucleus accumbens.
Topics: Action Potentials; Anesthetics, Local; Animals; Cocaine; Male; Memory; Nerve Net; Neural Inhibition; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2004 |
Dopamine mechanisms and cocaine reward.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Humans; Reward | 2004 |
Molecular mechanisms underlying the rewarding effects of cocaine.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Reward; Serotonin Plasma Membrane Transport Proteins; Symporters | 2004 |
The role of endocannabinoid transmission in cocaine addiction.
Topics: Animals; Cannabinoid Receptor Modulators; Cocaine; Cocaine-Related Disorders; Endocannabinoids; Humans; Reward; Self Administration; Synaptic Transmission | 2005 |
[Natural rewarding and drug rewarding].
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Heroin; Humans; Limbic System; Mesencephalon; Motivation; Reward; Ventral Tegmental Area | 2005 |
The "ups and downs" of signaling cascades in addiction.
Topics: Alcoholism; Animals; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Cyclic AMP; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ethanol; Guanine Nucleotide Dissociation Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Limbic System; Mice; Nuclear Matrix-Associated Proteins; Nucleus Accumbens; Phosphorylation; Prefrontal Cortex; Protein Kinases; Protein Processing, Post-Translational; Receptors, G-Protein-Coupled; Reward; RGS Proteins; Signal Transduction; Substance-Related Disorders; Transcription, Genetic; Ventral Tegmental Area | 2005 |
Three-dimensional models of neurotransmitter transporters and their interactions with cocaine and S-citalopram.
Topics: Antidepressive Agents; Citalopram; Cocaine; Depressive Disorder; Models, Molecular; Neurotransmitter Transport Proteins; Protein Conformation; Reward | 2006 |
The role of CART in the reward/reinforcing properties of psychostimulants.
Topics: Amphetamines; Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Gene Expression; Nerve Tissue Proteins; Reinforcement, Psychology; Reward | 2006 |
Maternal separation alters drug intake patterns in adulthood in rats.
Topics: Alcohol Drinking; Animals; Brain; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Epigenesis, Genetic; Maternal Deprivation; Rats; Receptors, Dopamine; Reward; Self Administration; Substance-Related Disorders | 2007 |
Cocaine withdrawal and neuro-adaptations in ion channel function.
Topics: Adaptation, Physiological; Animals; Calcium; Cocaine; Dopamine; Humans; Ion Channels; Neurons; Prefrontal Cortex; Receptors, Dopamine; Reward; Signal Transduction; Substance Withdrawal Syndrome | 2007 |
Nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: the dopamine-morphine hypothesis.
Topics: Alcohols; Animals; Cocaine; Humans; Models, Biological; Morphine; Nicotine; Reward; Signal Transduction | 2007 |
Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.
Topics: Animals; Brain Mapping; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Efferent Pathways; Fluorescent Dyes; Immunohistochemistry; Male; Models, Neurological; Nucleus Accumbens; Olfactory Pathways; Psychotropic Drugs; Rats; Rats, Wistar; Reward; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2007 |
The nucleus accumbens and reward: neurophysiological investigations in behaving animals.
Topics: Action Potentials; Animals; Association Learning; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Nucleus Accumbens; Rats; Reward; Self Administration | 2002 |
The role of acetylcholine in cocaine addiction.
Topics: Acetylcholine; Adaptation, Psychological; Animals; Cocaine; Cocaine-Related Disorders; Cognition; Disease Models, Animal; Humans; Learning; Memory; Neostriatum; Parasympathetic Nervous System; Reward | 2008 |
Getting specialized: presynaptic and postsynaptic dopamine D2 receptors.
Topics: Animals; Cocaine; Dopamine; Dopamine D2 Receptor Antagonists; Mice; Mice, Knockout; Motor Activity; Mutation; Neurons; Receptors, Dopamine D2; Receptors, Presynaptic; Reinforcement, Psychology; Reward; Synapses; Synaptic Transmission | 2009 |
Electrophysiological correlates of abused drugs: relation to natural rewards.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine; Electrophysiological Phenomena; Humans; Illicit Drugs; Neurons; Reward; Substance-Related Disorders | 2010 |
Cholinergic modulation of mesolimbic dopamine function and reward.
Topics: Acetylcholine; Animals; Cocaine; Dopamine; Feeding Behavior; Motivation; Neurons; Nucleus Accumbens; Reward; Self Administration; Substantia Nigra; Synapses; Ventral Tegmental Area | 2011 |
Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.
Topics: Adolescent; Black or African American; Case-Control Studies; Chi-Square Distribution; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Dopamine; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Haplotypes; Humans; Linkage Disequilibrium; Male; Polymorphism, Single Nucleotide; Receptor, Cannabinoid, CB1; Reward; United States | 2013 |
[Structural plasticity associated with drugs addiction].
Topics: Amphetamine; Animals; Brain; Cocaine; Humans; Morphine; Neuronal Plasticity; Nicotine; Reward; Substance-Related Disorders; Synapses | 2011 |
Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Humans; MicroRNAs; Neuronal Plasticity; Reward; Self Administration | 2013 |
Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Dynorphins; Gene Expression Regulation; Humans; Mammals; Morphine; Motivation; Narcotics; Nucleus Accumbens; Receptors, Neurotransmitter; Reward; Signal Transduction; Substance-Related Disorders; Transcriptional Activation | 2013 |
When a good taste turns bad: Neural mechanisms underlying the emergence of negative affect and associated natural reward devaluation by cocaine.
Topics: Animals; Avoidance Learning; Cocaine; Electromyography; Humans; Models, Animal; Nerve Net; Nucleus Accumbens; Rats; Reward; Taste | 2014 |
Sugar addiction: pushing the drug-sugar analogy to the limit.
Topics: Animals; Behavior, Addictive; Carbohydrates; Cocaine; Energy Intake; Food Preferences; Humans; Reward; Taste | 2013 |
Multiple faces of BDNF in cocaine addiction.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corpus Striatum; Craving; Disease Models, Animal; Mice; Neuronal Plasticity; Rats; Receptors, AMPA; Reward; Self Administration | 2015 |
Clock genes × stress × reward interactions in alcohol and substance use disorders.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Circadian Clocks; Circadian Rhythm Signaling Peptides and Proteins; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Gene-Environment Interaction; Humans; Hypothalamo-Hypophyseal System; Nicotine; Nicotinic Agonists; Pituitary-Adrenal System; Reward; Stress, Psychological; Substance-Related Disorders | 2015 |
[Depression and addiction comorbidity: towards a common molecular target?].
Topics: Anhedonia; Animals; Annexin A2; Appetitive Behavior; Cholinergic Neurons; Cocaine; Comorbidity; Depression; Depressive Disorder; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Humans; Interneurons; Mice; Mice, Knockout; Molecular Targeted Therapy; Nerve Tissue Proteins; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Optogenetics; Pleasure; Prevalence; Protein Transport; Receptors, Neurotransmitter; Reward; RNA Interference; S100 Proteins; Substance-Related Disorders | 2015 |
Reflections on: "A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function".
Topics: Animals; Cocaine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; GTP-Binding Proteins; Humans; Locus Coeruleus; Morphine; Nucleus Accumbens; Rats; Reward; Substance-Related Disorders; Up-Regulation | 2016 |
Prefrontal cortical BDNF: A regulatory key in cocaine- and food-reinforced behaviors.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Decision Making; Humans; Neuronal Plasticity; Prefrontal Cortex; Reward | 2016 |
Synaptic mechanisms underlying persistent cocaine craving.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Craving; Humans; Nerve Net; Neuronal Plasticity; Reward; Synapses | 2016 |
Addictive behaviour in experimental animals: prospects for translation.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Humans; Memory; Mice; Pharmaceutical Preparations; Primates; Rats; Reinforcement, Psychology; Reward; Translational Research, Biomedical | 2018 |
Neuronal mechanisms mediating pathological reward-related behaviors: A focus on silent synapses in the nucleus accumbens.
Topics: Animals; Cocaine; Drug-Seeking Behavior; Morphine; Neurons; Nucleus Accumbens; Reward; Synapses | 2018 |
A2AR-D2R Heteroreceptor Complexes in Cocaine Reward and Addiction.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Humans; Nucleus Accumbens; Receptor, Adenosine A2A; Receptors, Dopamine D2; Receptors, sigma; Reward; Sigma-1 Receptor | 2018 |
Central GLP-1 receptors: Novel molecular targets for cocaine use disorder.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Humans; Reward; Self Administration | 2019 |
The sigma-1 receptor as key common factor in cocaine and food-seeking behaviors.
Topics: Animals; Appetite; Calcium; Cocaine; Cocaine-Related Disorders; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Feeding Behavior; Humans; Ligands; Mitogen-Activated Protein Kinases; Neurons; Receptors, Dopamine; Receptors, Ghrelin; Receptors, sigma; Reward; Sigma-1 Receptor; Signal Transduction | 2019 |
Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function.
Topics: Adolescent; Age Factors; Amphetamine; Animals; Brain; Cannabinoids; Cocaine; Cognition; Critical Period, Psychological; Dopamine; Ethanol; Humans; Illicit Drugs; Models, Animal; Nicotine; Prefrontal Cortex; Recreational Drug Use; Reward | 2020 |
The role of mitochondria in cocaine addiction.
Topics: Animals; Antioxidants; Brain; Cocaine; Cocaine-Related Disorders; Energy Metabolism; Female; Glycolysis; Humans; Mice; Mitochondria; Mitochondrial Transmembrane Permeability-Driven Necrosis; Mitochondrial Turnover; Neuroglia; Organelle Biogenesis; Oxidative Phosphorylation; Oxidative Stress; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Reactive Oxygen Species; Reward; Substance Withdrawal Syndrome | 2021 |
Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein.
Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Ethanol; HIV Infections; HIV-1; Humans; Mice; Quality of Life; Reward; Substance-Related Disorders; tat Gene Products, Human Immunodeficiency Virus | 2021 |
Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking.
Topics: Adenosine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Male; Orexins; Reward; Self Administration; Sleep; Sleep Wake Disorders | 2021 |
Biphasic reward effects are characteristic of both lorcaserin and drugs of abuse: implications for treatment of substance use disorders.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Reward; Self Administration; Substance-Related Disorders | 2022 |
12 trial(s) available for cocaine and s,n,n'-tripropylthiocarbamate
| Article | Year |
|---|---|
Attenuation of the euphoric effects of cocaine by the dopamine D1/D5 antagonist ecopipam (SCH 39166)
Topics: Adult; Behavior, Addictive; Benzazepines; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Euphoria; Female; Humans; Male; Receptors, Dopamine; Reward | 1999 |
A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependence.
Topics: Adult; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Patient Compliance; Reward; Substance Abuse Detection; Treatment Outcome | 2002 |
Effects of isradipine on cocaine-induced subjective mood.
Topics: Adolescent; Adult; Affect; Area Under Curve; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isradipine; Male; Reproducibility of Results; Reward; Stimulation, Chemical; Surveys and Questionnaires | 2004 |
Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population.
Topics: Adult; Behavior Therapy; Bupropion; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Comorbidity; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heroin Dependence; Humans; Male; Methadone; Placebos; Psychiatric Status Rating Scales; Reward; Substance Abuse Detection | 2006 |
Comparable efficacy of contingency management for cocaine dependence among African American, Hispanic, and White methadone maintenance clients.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Behavior Therapy; Black or African American; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Female; Hispanic or Latino; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Psychiatric Status Rating Scales; Reward; Substance Abuse Detection; Treatment Outcome; White People | 2009 |
Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers.
Topics: Adolescent; Adult; Buprenorphine; Choice Behavior; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Seeking Behavior; Female; Humans; Hydromorphone; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Reinforcement Schedule; Reward; Substance Withdrawal Syndrome | 2010 |
Contingency management with community reinforcement approach or twelve-step facilitation drug counseling for cocaine dependent pregnant women or women with young children.
Topics: Adult; Alcoholism; Ambulatory Care; Behavior Therapy; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Comorbidity; Depressive Disorder, Major; Female; Humans; Male; Maternal Behavior; Pregnancy; Pregnancy Complications; Pregnant Women; Psychiatric Status Rating Scales; Reinforcement, Psychology; Residence Characteristics; Reward; Self-Help Groups; Time Factors; Treatment Outcome; Urban Population | 2011 |
Influence of acute bupropion pre-treatment on the effects of intranasal cocaine.
Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Bupropion; Choice Behavior; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Reward | 2012 |
Gastric bypass surgery for obesity decreases the reward value of a sweet-fat stimulus as assessed in a progressive ratio task.
Topics: Adult; Appetite; Body Mass Index; Candy; Case-Control Studies; Cohort Studies; Diet, Reducing; Feeding Behavior; Female; Food Preferences; Gastric Bypass; Humans; Male; Middle Aged; Obesity; Patient Compliance; Reward; United Kingdom; Vegetables; Weight Loss | 2012 |
Impulsivity, "advergames," and food intake.
Topics: Advertising; Appetite Regulation; Candy; Child; Cues; Eating; Energy Intake; Female; Food; Food Preferences; Humans; Impulsive Behavior; Individuality; Inhibition, Psychological; Male; Motivation; Pediatric Obesity; Reward; Video Games | 2014 |
The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description.
Topics: Adult; Behavior, Addictive; Biomedical Research; Brain; Cocaine; Cross-Over Studies; Drug Discovery; Ethanol; Female; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Middle Aged; Naltrexone; Neurokinin-1 Receptor Antagonists; Pharmaceutical Preparations; Receptors, Dopamine D3; Receptors, Neurokinin-1; Reward; Secondary Prevention; Substance-Related Disorders | 2015 |
Violation of eating expectancies does not reduce conditioned desires for chocolate.
Topics: Adolescent; Adult; Appetite Regulation; Behavior Therapy; Candy; Chocolate; Conditioning, Psychological; Cues; Diet, Reducing; Extinction, Psychological; Female; Food Preferences; Humans; Hyperphagia; Netherlands; Patient Compliance; Patient Education as Topic; Reward; Time Factors; Young Adult | 2016 |
977 other study(ies) available for cocaine and s,n,n'-tripropylthiocarbamate
| Article | Year |
|---|---|
Effects of intravenous cocaine, diethylpropion, d-amphetamine and perphenazine on responding maintained by food delivery and shock avoidance in rhesus monkeys.
Topics: Animals; Cocaine; Conditioning, Operant; Dextroamphetamine; Diethylpropion; Haplorhini; Macaca mulatta; Male; Perphenazine; Punishment; Reinforcement Schedule; Reward | 1978 |
Euphorigenic drugs: effects on the reward pathways of the brain.
Topics: Amphetamine; Animals; Brain; Cocaine; Electroencephalography; Euphoria; Morphine; Narcotic Antagonists; Narcotics; Neural Pathways; Pentazocine; Phencyclidine; Rats; Reward; Self Stimulation | 1979 |
NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dopamine; Glutamates; Glutamic Acid; Heroin; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration | 1992 |
Role of dopamine receptors in the nucleus accumbens in the rewarding properties of cocaine.
Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Haloperidol; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration | 1992 |
Attenuation of drinking sweetened water following calcium channel blockade.
Topics: Animals; Calcium Channel Blockers; Cocaine; Dihydropyridines; Dose-Response Relationship, Drug; Drinking Behavior; Female; Injections, Intraventricular; Isradipine; Male; Rats; Rats, Inbred Strains; Reward; Taste | 1992 |
Cocaine euphoria, dysphoria, and tolerance assessed using drug-induced changes in brain-stimulation reward.
Topics: Animals; Brain; Cocaine; Depression; Drug Tolerance; Euphoria; Male; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1992 |
Calcium antagonists isradipine and nimodipine suppress cocaine and morphine intravenous self-administration in drug-naive mice.
Topics: Animals; Calcium Channel Blockers; Cocaine; Dihydropyridines; Dopamine; Injections, Intravenous; Isradipine; Mice; Morphine; Nimodipine; Reinforcement, Psychology; Reward; Self Administration | 1992 |
Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions.
Topics: Animals; Cocaine; Dopamine; Male; Morphine; Nucleus Accumbens; Phosphorylation; Rats; Rats, Inbred Strains; Reward; Tegmentum Mesencephali; Time Factors; Tyrosine 3-Monooxygenase | 1991 |
Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine- and cocaine-regulated phosphoproteins.
Topics: Animals; Brain; Cocaine; Dopamine; Genotype; Morphine; Phosphoproteins; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reward; Tyrosine 3-Monooxygenase | 1991 |
Construct validity of a self-stimulation threshold paradigm: effects of reward and performance manipulations.
Topics: Animals; Cocaine; Curare; Electric Stimulation; Male; Motivation; Rats; Rats, Inbred Strains; Reaction Time; Reward; Self Stimulation; Sensory Thresholds | 1992 |
Cocaine enhances the reward value of medial prefrontal cortex self-stimulation.
Topics: Animals; Cocaine; Differential Threshold; Electric Stimulation; Frontal Lobe; Male; Medial Forebrain Bundle; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1991 |
Cocaine abstinence following chronic treatment alters cerebral metabolism in dopaminergic reward regions. Bromocriptine enhances recovery.
Topics: Analysis of Variance; Animals; Autoradiography; Brain; Bromocriptine; Carbon Radioisotopes; Cocaine; Deoxyglucose; Dopamine; Glucose; Male; Organ Specificity; Rats; Rats, Inbred Strains; Reference Values; Reward; Substance Withdrawal Syndrome | 1991 |
The role of the olfactory tubercle in the effects of cocaine, morphine and brain-stimulation reward.
Topics: Animals; Brain; Cocaine; Electric Stimulation; Glucose; Male; Morphine; Olfactory Bulb; Rats; Rats, Inbred F344; Reward; Sodium Chloride; Tissue Distribution | 1991 |
Genetic determinants of susceptibility to the rewarding and other behavioral actions of cocaine.
Topics: Animals; Appetitive Behavior; Arousal; Brain; Cocaine; Genotype; Mice; Mice, Inbred Strains; Models, Genetic; Polymorphism, Genetic; Reward; Social Environment; Species Specificity; Substance-Related Disorders | 1991 |
Preexposure sensitizes rats to the rewarding effects of cocaine.
Topics: Animals; Cocaine; Conditioning, Operant; Injections, Intravenous; Male; Motor Activity; Rats; Rats, Inbred Strains; Reward; Self Administration | 1990 |
Postcocaine depression and sensitization of brain-stimulation reward: analysis of reinforcement and performance effects.
Topics: Animals; Cocaine; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Male; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Self Administration; Self Stimulation; Tegmentum Mesencephali; Time Factors | 1990 |
Cocaine alters opiate receptor binding in critical brain reward regions.
Topics: Animals; Autoradiography; Brain; Cocaine; Globus Pallidus; Hypothalamic Area, Lateral; Male; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Reward | 1989 |
Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine.
Topics: Amphetamine; Animals; Chlorides; Cocaine; Conditioning, Operant; Lithium; Lithium Chloride; Male; Morphine; Rats; Rats, Inbred Strains; Reward | 1989 |
Chronic imipramine does not block cocaine-induced increases in brain stimulation reward.
Topics: Animals; Brain; Cocaine; Drug Interactions; Electric Stimulation; Imipramine; Male; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1989 |
Street-wise crack research.
Topics: Acquired Immunodeficiency Syndrome; Behavior; Brain; Cocaine; Disease Outbreaks; Dopamine; Drug and Narcotic Control; Humans; Legislation, Drug; Reward; Substance-Related Disorders; United States | 1989 |
Neuroleptics block the positive reinforcing effects of amphetamine but not of morphine as measured by place conditioning.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Drug Interactions; Flupenthixol; Male; Morphine; Orientation; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward | 1985 |
Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward.
Topics: Animals; Catecholamines; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Haloperidol; Male; Mesencephalon; Naloxone; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1988 |
Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Cocaine; Dialysis; Dopamine; Eating; Electric Stimulation; Extracellular Space; Food; Homovanillic Acid; Hypothalamus; Kinetics; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Septal Nuclei | 1988 |
The effect of chronic cocaine on self-stimulation train-duration thresholds.
Topics: Animals; Cocaine; Male; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1988 |
Naloxone attenuation of the effect of cocaine on rewarding brain stimulation.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Euphoria; Male; Medial Forebrain Bundle; Naloxone; Rats; Reward; Tegmentum Mesencephali | 1987 |
Rewarding and aversive effects of stimulant drugs in infant rats.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Female; Learning; Male; Odorants; Phenylpropanolamine; Rats; Rats, Inbred Strains; Reward | 1987 |
Intravenous cocaine-induced place preference: attenuation by haloperidol.
Topics: Animals; Cocaine; Conditioning, Psychological; Haloperidol; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Reward | 1987 |
Sex difference in reward asymmetry and effects of cocaine.
Topics: Animals; Cocaine; Electric Stimulation; Female; Functional Laterality; Hypothalamic Area, Lateral; Male; Rats; Rats, Inbred Strains; Reward; Self Administration; Self Stimulation; Sex Factors | 1986 |
The reinforcing properties of diazepam under several conditions in the rhesus monkey.
Topics: Animals; Cocaine; Diazepam; Female; Injections, Intravenous; Macaca mulatta; Male; Pentobarbital; Reinforcement Schedule; Reward; Self Administration | 1985 |
Brain-stimulation reward: a model for the neuronal bases for drug-induced euphoria.
Topics: Animals; Brain; Cocaine; Dextroamphetamine; Electric Stimulation; Euphoria; Humans; Models, Neurological; Morphine; Nalbuphine; Neural Pathways; Neurons; Rats; Reward; Self Stimulation; Substance-Related Disorders; Tripelennamine | 1985 |
Pharmaco-ontogeny of reward: enhancement of self-stimulation by D-amphetamine and cocaine in 3- and 10-day-old rats.
Topics: Aging; Amphetamine; Animals; Animals, Newborn; Brain; Cocaine; Electric Stimulation; Female; Male; Rats; Rats, Inbred Strains; Reaction Time; Reward; Self Stimulation | 1986 |
Comparison of fixed-ratio and progressive-ratio schedules of maintenance of stimulant drug-reinforced responding.
Topics: Animals; Cocaine; Isoquinolines; Macaca mulatta; Male; Nomifensine; Psychopharmacology; Reinforcement Schedule; Reward | 1985 |
Supersensitivity and dependence on cocaine.
Topics: Cocaine; Feedback; Humans; Neurotransmitter Agents; Norepinephrine; Receptors, Drug; Reward; Substance-Related Disorders | 1968 |
Enhancement of coaine of intra-cranial self-stimulation in the rat.
Topics: Amphetamine; Animals; Catecholamines; Cocaine; Conditioning, Operant; Male; Mesencephalon; Rats; Reward; Self Stimulation; Stimulation, Chemical | 1970 |
Opiate rewarding action: independence of the cells of the lateral hypothalamus.
Topics: Animals; Cocaine; Heroin; Hypothalamus; Kainic Acid; Male; Motivation; Rats; Rats, Inbred Strains; Reward; Self Administration | 1981 |
The delta-opioid receptor antagonist naltrindole prevents sensitization to the conditioned rewarding effects of cocaine.
Topics: Animals; Association Learning; Cocaine; Conditioning, Operant; Drug Interactions; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reward; Sensitivity and Specificity | 1995 |
Tegmental pedunculopontine nucleus lesions do not block cocaine reward.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Motivation; Narcotics; Pons; Rats; Rats, Wistar; Reward; Tegmentum Mesencephali | 1995 |
Increased sensitivity to cocaine place-preference conditioning by septal lesions in rats.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Hippocampus; Learning; Male; Rats; Rats, Sprague-Dawley; Reward; Septal Nuclei; Stereotaxic Techniques | 1995 |
Sertindole antagonizes morphine-, cocaine-, and methamphetamine-induced place preference in the rat.
Topics: Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Fluphenazine; Haloperidol; Imidazoles; Indoles; Male; Methamphetamine; Morphine; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior | 1995 |
Effects of monoamine reuptake inhibitors on cocaine self-administration in rats.
Topics: Animals; Biogenic Monoamines; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intravenous; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 1995 |
Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.
Topics: Amphetamine; Animals; Benzazepines; Cocaine; Conditioning, Classical; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Male; Morphine; Raclopride; Rats; Rats, Sprague-Dawley; Reward; Salicylamides; Time Factors | 1995 |
Conditioned place preference induced by delta 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Classical; Dronabinol; Food; Male; Morphine; Rats; Reward | 1995 |
Regulation of cytochrome c oxidase subunit mRNA and enzyme activity in rat brain reward regions during withdrawal from chronic cocaine.
Topics: Animals; Brain; Caudate Nucleus; Cocaine; Electron Transport Complex IV; Isoenzymes; Male; Nucleus Accumbens; Prefrontal Cortex; Putamen; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors | 1995 |
Differential effects of excitotoxic lesions of the amygdala on cocaine-induced conditioned locomotion and conditioned place preference.
Topics: Amygdala; Animals; Cocaine; Conditioning, Operant; Gliosis; Male; Motor Activity; Oxidopamine; Quinolinic Acid; Rats; Reward | 1993 |
Differential modification of the rewarding effects of methamphetamine and cocaine by opioids and antihistamines.
Topics: Animals; Appetite; Chlorpheniramine; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Histamine Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward | 1993 |
Differences in bioavailability between cocaine and cocaethylene and their implications for drug-reward studies.
Topics: Animals; Biological Availability; Cocaine; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reward | 1994 |
Effects of cocaine and GBR-12909 on brain stimulation reward.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Electrodes, Implanted; Male; Medial Forebrain Bundle; Motor Activity; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation | 1994 |
Assessment of the relative contribution of peripheral and central components in cocaine place conditioning.
Topics: Animals; Central Nervous System; Cocaine; Conditioning, Psychological; Dopamine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Peripheral Nervous System; Procaine; Rats; Rats, Wistar; Reward; Substance-Related Disorders | 1994 |
Biphasic changes in mesolimbic dopamine signal during cocaine self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine; Electrochemistry; Limbic System; Male; Microdialysis; Microelectrodes; Nucleus Accumbens; Procaine; Rats; Reward; Self Administration | 1994 |
Nitric oxide synthesis inhibition does not affect brain stimulation reward.
Topics: Animals; Arginine; Brain; Cocaine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Reward; Self Stimulation | 1994 |
A simple computer-based method for performing and analyzing intracranial self-stimulation experiments in rats.
Topics: Animals; Biogenic Monoamines; Brain; Cocaine; Dextroamphetamine; Electric Stimulation; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Stimulation; Synaptic Transmission | 1993 |
Extinction of cocaine-induced place approach in rats: a validation of the "biased" conditioning procedure.
Topics: Animals; Cocaine; Conditioning, Classical; Conditioning, Operant; Extinction, Psychological; Habituation, Psychophysiologic; Male; Rats; Rats, Inbred Strains; Reward | 1993 |
Withdrawal following cocaine self-administration decreases regional cerebral metabolic rate in critical brain reward regions.
Topics: Animals; Autoradiography; Brain; Cocaine; Deoxyglucose; Male; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tissue Distribution | 1993 |
Lack of involvement of delta-opioid receptors in mediating the rewarding effects of cocaine.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reward; Self Administration; Time Factors | 1995 |
kappa-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Cocaine; Conditioning, Psychological; Dopamine; Male; Naltrexone; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward | 1996 |
Neurochemical mechanisms underlying responses to psychostimulants.
Topics: Animals; Behavior; Brain; Brain Chemistry; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Humans; Methylphenidate; Opioid-Related Disorders; Raclopride; Receptors, Dopamine; Research Design; Reward; Salicylamides; Substance-Related Disorders | 1996 |
Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities.
Topics: Adaptation, Physiological; Adult; Autoradiography; Brain; Cocaine; Drug Overdose; Humans; Image Processing, Computer-Assisted; Neural Pathways; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward; Tetrahydronaphthalenes; Tissue Distribution | 1996 |
Locomotor response to novelty does not predict cocaine place preference conditioning in rats.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Environment; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward | 1996 |
Neural signals in the monkey ventral striatum related to motivation for juice and cocaine rewards.
Topics: Animals; Cocaine; Corpus Striatum; Female; Macaca mulatta; Male; Models, Psychological; Motivation; Neurons; Reaction Time; Reward | 1996 |
Effects of calcium channel antagonists on the reinforcing properties of morphine, ethanol and cocaine as measured by place conditioning.
Topics: Animals; Calcium; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Ethanol; Male; Morphine; Nifedipine; Rats; Rats, Wistar; Reward; Substance-Related Disorders | 1996 |
Inhibition of nitric oxide synthesis reduces intravenous cocaine self-administration in the rat.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Opioid-Related Disorders; Rats; Rats, Wistar; Reward; Self Administration | 1996 |
Cannabinoid receptor gene (CNR1): association with i.v. drug use.
Topics: Administration, Inhalation; Administration, Oral; Adult; Alcoholism; Alleles; Amphetamines; Cocaine; Comorbidity; Disease Susceptibility; Evoked Potentials; Female; Gene Frequency; Genotype; Heroin; Heroin Dependence; Humans; Injections, Intravenous; Male; Middle Aged; Receptors, Cannabinoid; Receptors, Drug; Reward; Risk Factors; Smoking; Substance Abuse, Intravenous; Substance-Related Disorders; Trinucleotide Repeats | 1997 |
Place conditioning with cocaine and the dopamine uptake inhibitor GBR12783.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Male; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Reward | 1996 |
Effect of adrenalectomy on cocaine facilitation of lateral hypothalamic self-stimulation.
Topics: Adrenal Glands; Adrenalectomy; Animals; Cocaine; Corticosterone; Drug Evaluation, Preclinical; Hypothalamic Area, Lateral; Male; Narcotics; Rats; Rats, Sprague-Dawley; Restraint, Physical; Reward; Self Administration; Self Stimulation; Stress, Physiological | 1997 |
Synergistic effects of cocaine and dizocilpine (MK-801) on brain stimulation reward.
Topics: Animals; Brain; Cocaine; Dizocilpine Maleate; Drug Synergism; Male; Rats; Reward; Self Stimulation | 1997 |
Cocaine reward and locomotor activity in C57BL/6J and 129/SvJ inbred mice and their F1 cross.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Genotype; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Narcotics; Reward; Species Specificity | 1997 |
Choice between cocaine and food in a discrete-trials procedure in monkeys: a unit price analysis.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Food; Macaca mulatta; Male; Narcotics; Reaction Time; Reward; Self Administration | 1997 |
Gamma-vinyl GABA attenuates cocaine-induced lowering of brain stimulation reward thresholds.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred F344; Reward; Vigabatrin | 1997 |
Synergistic effects of cocaine with lateral hypothalamic brain stimulation reward: lack of tolerance or sensitization.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Hypothalamus; Male; Rats; Reward; Self Stimulation | 1997 |
Isradipine blocks cocaine's ability to facilitate pressing for intracranial stimulation.
Topics: Animals; Calcium Channel Blockers; Cocaine; Isradipine; Male; Medial Forebrain Bundle; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation | 1997 |
Mixed D2/5-HT2A antagonism of cocaine-induced facilitation of brain stimulation reward.
Topics: Animals; Brain; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reward; Risperidone; Self Stimulation; Serotonin Antagonists | 1998 |
Comparison of mesocorticolimbic neuronal responses during cocaine and heroin self-administration in freely moving rats.
Topics: Action Potentials; Animals; Behavior, Animal; Cerebral Cortex; Cocaine; Dopamine Uptake Inhibitors; Electrophysiology; Heroin; Limbic System; Locomotion; Male; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance-Related Disorders | 1998 |
Alterations in the reinforcing efficacy of cocaine in adult rats following prenatal exposure to cocaine.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reinforcement Schedule; Reward; Sucrose | 1998 |
Sensitization to the conditioned rewarding effects of morphine and cocaine: differential effects of the kappa-opioid receptor agonist U69593.
Topics: Analgesics; Animals; Benzeneacetamides; Cocaine; Conditioning, Operant; Cues; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward | 1998 |
Isradipine combined with naltrexone persistently reduces the reward-relevant effects of cocaine and alcohol.
Topics: Animals; Body Weight; Calcium Channel Blockers; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Drinking; Drug Interactions; Ethanol; Isradipine; Male; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward | 1998 |
Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice.
Topics: Animals; Carrier Proteins; Choice Behavior; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Mice, Knockout; Nerve Tissue Proteins; Restriction Mapping; Reward; Serotonin Plasma Membrane Transport Proteins | 1998 |
Sensitization to the rewarding effects of the specific dopamine uptake inhibitor GBR12783.
Topics: Animals; Anxiety; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Image Processing, Computer-Assisted; Male; Morphine; Narcotics; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Stereotyped Behavior | 1998 |
Polydrug self-administration in rats: cocaine-heroin is more rewarding than cocaine-alone.
Topics: Animals; Cocaine; Conditioning, Operant; Drug Synergism; Heroin; Injections, Intravenous; Male; Narcotics; Rats; Reward; Self Administration | 1998 |
Phasic firing time locked to cocaine self-infusion and locomotion: dissociable firing patterns of single nucleus accumbens neurons in the rat.
Topics: Action Potentials; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Electrophysiology; Locomotion; Motivation; Neurons; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reaction Time; Reward; Self Administration; Stereotyped Behavior | 1998 |
Pre-exposure to alcohol does not sensitize to the rewarding effects of cocaine.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Ethanol; Male; Rats; Reward | 1998 |
Regulation of cocaine reward by CREB.
Topics: Animals; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Dynorphins; Gene Expression; Gene Expression Regulation; Gene Transfer Techniques; Genetic Vectors; Naltrexone; Narcotic Antagonists; Neurons; Nucleus Accumbens; Point Mutation; Rats; Receptors, Opioid, kappa; Reward; RNA, Messenger; Simplexvirus | 1998 |
Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm.
Topics: Amphetamine; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward | 1998 |
Caffeine place conditioning in rats: comparison with cocaine and ethanol.
Topics: Analysis of Variance; Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Cues; Ethanol; Male; Rats; Rats, Wistar; Reward | 1998 |
Repeated neonatal maternal separation alters intravenous cocaine self-administration in adult rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzazepines; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Male; Maternal Deprivation; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Salicylamides; Self Administration; Sex Factors | 1999 |
The effects of neonatal cocaine exposure on a play-rewarded spatial discrimination task in juvenile rats.
Topics: Animals; Animals, Newborn; Body Weight; Cocaine; Discrimination Learning; Female; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward | 1999 |
RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist.
Topics: Animals; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Indoles; Male; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Self Stimulation; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitization.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Psychological; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Synergism; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 1999 |
Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Feeding Behavior; Injections, Intravenous; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuronal Plasticity; Prefrontal Cortex; Reward; Self Administration; Tissue Plasminogen Activator | 1999 |
Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug Synergism; Female; Infusion Pumps; Male; Mice; Mice, Knockout; Motor Activity; Nerve Growth Factors; Rats; Rats, Sprague-Dawley; Reward | 1999 |
Caffeine, acting on adenosine A(1) receptors, prevents the extinction of cocaine-seeking behavior in mice.
Topics: Animals; Behavior, Animal; Caffeine; Cocaine; Extinction, Psychological; Male; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Reward; Substance Abuse, Intravenous; Theophylline; Triazoles; Xanthines | 1999 |
The irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor gamma-vinyl-GABA blocks cocaine self-administration in rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Cocaine; Conditioning, Operant; Enzyme Inhibitors; Food; gamma-Aminobutyric Acid; Male; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Vigabatrin | 1999 |
Involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Food; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration | 1999 |
Changes in progressive ratio responding for intravenous cocaine throughout the reproductive process in female rats.
Topics: Animals; Appetitive Behavior; Behavior, Addictive; Central Nervous System Stimulants; Cocaine; Dietary Sucrose; Estrus; Female; Injections, Intravenous; Maternal Behavior; Narcotics; Pregnancy; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reproduction; Reward; Self Administration; Sexual Behavior, Animal | 1999 |
Genetic differences in cocaine-induced conditioned place preference in mice depend on conditioning trial duration.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reward; Species Specificity; Time Factors | 1999 |
The suppressive effects of LiCl, sucrose, and drugs of abuse are modulated by sucrose concentration in food-deprived rats.
Topics: Analysis of Variance; Animals; Appetite; Avoidance Learning; Cocaine; Conditioning, Classical; Dietary Sucrose; Dose-Response Relationship, Drug; Drinking Behavior; Food Deprivation; Food Preferences; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Taste | 1999 |
Periadolescent nicotine exposure reduces cocaine reward in adult mice.
Topics: Age Factors; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Nicotine; Reinforcement, Psychology; Reward; Self Administration; Sensitivity and Specificity; Weight Gain | 1999 |
Conditioned increase in place preference by access to novel objects: antagonism by MK-801.
Topics: Animals; Appetite; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Environment; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Substance-Related Disorders | 1999 |
Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Gene Expression Regulation; Genetic Variation; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Mice, Transgenic; Motor Activity; MPTP Poisoning; Nerve Tissue Proteins; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Reward; Serotonin; Substantia Nigra; Transgenes; Tyrosine 3-Monooxygenase | 1999 |
Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Excitatory Amino Acid Antagonists; Functional Laterality; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward; Stereotyped Behavior; Time Factors | 1999 |
Cocaine reward and dopamine receptors: love at first site.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Euphoria; Humans; Rats; Receptors, Dopamine; Reward | 1999 |
Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats.
Topics: Adenosine; Animals; Brain; Caffeine; Cocaine; Differential Threshold; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reaction Time; Receptors, Purinergic P1; Reference Values; Reward; Substance Withdrawal Syndrome; Theobromine | 1999 |
Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3, 4-methylenedioxymethamphetamine (MDMA).
Topics: Animals; Appetite; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward | 2000 |
NGFI-B and nor1 mRNAs are upregulated in brain reward pathways by drugs of abuse: different effects in Fischer and Lewis rats.
Topics: Animals; Brain; Cocaine; Corpus Striatum; DNA-Binding Proteins; Gyrus Cinguli; Male; Morphine; Narcotics; Nerve Tissue Proteins; Nuclear Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reward; RNA, Messenger; Species Specificity; Time Factors; Transcription Factors; Up-Regulation | 2000 |
Dissociation of primary and secondary reward-relevant limbic nuclei in an animal model of relapse.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Infusion Pumps, Implantable; Limbic System; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Sodium Channels; Tetrodotoxin | 2000 |
Cocaine potentiates ethanol-induced excitation of dopaminergic reward neurons in the ventral tegmental area.
Topics: Animals; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Drug Synergism; Ethanol; Extracellular Space; Ketanserin; Neurons; Rats; Rats, Inbred F344; Reward; Serotonin Antagonists; Sulpiride; Ventral Tegmental Area | 2000 |
Effects of phentermine on responding maintained by progressive-ratio schedules of cocaine and food delivery in rhesus monkeys.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Food; Infusions, Intravenous; Injections, Intramuscular; Macaca mulatta; Male; Phentermine; Reinforcement Schedule; Reward | 1999 |
Factors that determine a propensity for cocaine-seeking behavior during abstinence in rats.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Locomotion; Male; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Self Administration; Substance Withdrawal Syndrome | 2000 |
Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Electrodes, Implanted; Electrophysiology; Food; Injections, Intravenous; Male; Nerve Net; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Water | 2000 |
Rewarding effects of opiates are absent in mice lacking the receptor for substance P.
Topics: Animals; Cocaine; Conditioning, Classical; Corpus Striatum; Cyclic AMP; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Reward | 2000 |
Effects of the non-competitive NMDA-receptor antagonist memantine on morphine- and cocaine-induced potentiation of lateral hypothalamic brain stimulation reward.
Topics: Analgesics, Opioid; Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; Memantine; Morphine; Rats; Rats, Long-Evans; Reward | 2000 |
Effects of methyllycaconitine (MLA), an alpha 7 nicotinic receptor antagonist, on nicotine- and cocaine-induced potentiation of brain stimulation reward.
Topics: Aconitine; Animals; Cocaine; Dopamine Uptake Inhibitors; Hypothalamic Area, Lateral; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reward; Ventral Tegmental Area | 2000 |
Simultaneous monitoring of conditioned place preference and locomotor sensitization following repeated administration of cocaine and methamphetamine.
Topics: Animals; Association Learning; Cocaine; Conditioning, Psychological; Drug Resistance; Environment; Locomotion; Male; Methamphetamine; Mice; Monitoring, Physiologic; Reward | 2000 |
Dopamine D3 receptor agents as potential new medications for drug addiction.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Naphthalenes; Neurons; Nucleus Accumbens; Pyrrolidines; Rats; Receptors, Dopamine; Reward | 2000 |
Firing rate of nucleus accumbens neurons is dopamine-dependent and reflects the timing of cocaine-seeking behavior in rats on a progressive ratio schedule of reinforcement.
Topics: Animals; Appetitive Behavior; Cocaine; Dopamine; Dopamine D2 Receptor Antagonists; Electrodes, Implanted; Injections, Intravenous; Male; Neural Inhibition; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine D1; Reinforcement Schedule; Reward; Self Administration | 2000 |
An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-(p-fluorophenyl)-2-propyltropanes.
Topics: Animals; Behavior, Animal; Biological Transport; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Design; Ligands; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Molecular Structure; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Radioligand Assay; Rats; Reward; Serotonin; Tropanes | 2000 |
Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Injections, Intravenous; Male; Nucleus Accumbens; Rats; Reward; Self Administration; Time Factors | 2000 |
Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference.
Topics: Animals; Anisoles; Antipsychotic Agents; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Ethylenediamines; Male; Mice; Mice, Inbred C57BL; Narcotic Antagonists; Propylamines; Receptors, sigma; Reward | 2000 |
Cocaine-seeking by rats: regulation, reinforcement and activation.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Male; Rats; Reinforcement, Psychology; Reward; Self Administration | 2000 |
Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II.
Topics: Animals; Brain; Cocaine; Diet, Reducing; Dopamine; Enkephalin, D-Penicillamine (2,5)-; Male; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Reward | 2000 |
Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice.
Topics: Animals; Avoidance Learning; Cannabinoids; Cocaine; Drug Administration Schedule; Exploratory Behavior; Injections, Intraperitoneal; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Receptors, Cannabinoid; Receptors, Drug; Reward | 2000 |
Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties.
Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; DNA-Binding Proteins; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Drug Antagonism; Enzyme Activation; ets-Domain Protein Elk-1; Immunohistochemistry; Male; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Motor Activity; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reward; Transcription Factors | 2000 |
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Addictive; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Knockout; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, Cannabinoid; Receptors, Drug; Reward | 2001 |
Cocaine induces conditioned place preference and increases locomotor activity in male Japanese quail.
Topics: Animals; Cocaine; Conditioning, Operant; Coturnix; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Male; Motor Activity; Reward; Salicylamides; Stimulation, Chemical | 2001 |
Novel monoamine transporter ligands reduce cocaine-induced enhancement of brain stimulation reward.
Topics: Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Electric Stimulation; Ligands; Male; Neurotransmitter Uptake Inhibitors; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reward | 2001 |
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.
Topics: Animals; Biogenic Monoamines; Body Weight; Brain; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Gene Deletion; Genotype; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reward; Serotonin Plasma Membrane Transport Proteins | 2001 |
Relapse to cocaine-seeking after hippocampal theta burst stimulation.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Electric Stimulation; Electrodes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamic Acid; Hippocampus; Injections, Intravenous; Kynurenic Acid; Medial Forebrain Bundle; Memory; N-Methylaspartate; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration; Synaptic Transmission; Theta Rhythm; Ventral Tegmental Area | 2001 |
Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Motor Activity; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Recurrence; Reward; Self Administration | 2001 |
Drug addiction. Zapping memory center triggers drug craving.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Electric Stimulation; Extinction, Psychological; Glutamic Acid; Hippocampus; Injections, Intravenous; Medial Forebrain Bundle; Memory; Rats; Recurrence; Reward; Self Administration; Ventral Tegmental Area | 2001 |
Blockade of D1 dopamine receptors in the ventral tegmental area decreases cocaine reward: possible role for dendritically released dopamine.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Dendrites; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Antagonism; Drug Synergism; Ketanserin; Male; Microinjections; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reinforcement, Psychology; Reward; Self Administration; Serotonin Antagonists; Ventral Tegmental Area | 2001 |
Following the trace of elusive amines.
Topics: Animals; Biogenic Amines; Brain Chemistry; Cocaine; Consensus Sequence; Drosophila melanogaster; Food; GTP-Binding Proteins; Hemodynamics; Humans; Insect Proteins; Nerve Tissue Proteins; Neurotransmitter Agents; Phenethylamines; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Reward; Tyramine; Tyrosine Decarboxylase | 2001 |
A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues.
Topics: Animals; Behavior, Animal; Cacao; Candy; Cell Count; Conditioning, Psychological; Cues; Learning; Male; Motor Activity; Neural Pathways; Neuronal Plasticity; Neurons; Nicotine; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Tobacco Use Disorder | 2001 |
Additive effects of intra-accumbens infusion of the cAMP-specific phosphodiesterase inhibitor, rolipram and cocaine on brain stimulation reward.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cocaine; Drug Administration Routes; Drug Synergism; Nucleus Accumbens; Phosphodiesterase Inhibitors; Rats; Reward; Rolipram | 2001 |
Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor.
Topics: Animals; Brain; Cocaine; Conditioning, Psychological; Crosses, Genetic; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Radioligand Assay; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reward | 2001 |
Mouse strain differences in opiate reward learning are explained by differences in anxiety, not reward or learning.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Cues; Diazepam; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Modulators; Learning; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Motivation; Naloxone; Narcotics; Pentobarbital; Phenotype; Reward; Species Specificity | 2001 |
Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine.
Topics: Amphetamine; Animals; Cocaine; Endorphins; Ethanol; Extracellular Space; Male; Microdialysis; Motivation; Nicotine; Nucleus Accumbens; Radioimmunoassay; Rats; Rats, Long-Evans; Reward; Synaptic Transmission | 2001 |
Altered responsiveness to cocaine in rats exposed to methylphenidate during development.
Topics: Adaptation, Physiological; Adult; Aging; Animals; Central Nervous System Stimulants; Child; Cocaine; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Humans; Methylphenidate; Nucleus Accumbens; Rats; Receptors, AMPA; Reward; Time Factors | 2002 |
Rats prefer cocaine over nicotine in a two-lever self-administration choice test.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Infusion Pumps; Male; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder | 2002 |
Impairments of reversal learning and response perseveration after repeated, intermittent cocaine administrations to monkeys.
Topics: Animals; Chlorocebus aethiops; Cocaine; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Female; Male; Reinforcement Schedule; Reversal Learning; Reward; Substance Withdrawal Syndrome | 2002 |
Effects of excitotoxic lesions of the basolateral amygdala on cocaine-seeking behavior and cocaine conditioned place preference in rats.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Denervation; Discrimination Learning; Exploratory Behavior; Extinction, Psychological; Male; Motor Activity; Neurotoxins; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2002 |
The effect of nitric oxide synthesis inhibition on intravenous cocaine self-administration.
Topics: Animals; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Long-Evans; Reward; Self Administration | 2002 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
Effects of a newly synthesized kappa-opioid receptor agonist, TRK-820, on the discriminative stimulus and rewarding effects of cocaine in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine; Conditioning, Psychological; Discrimination Learning; Dose-Response Relationship, Drug; Male; Morphinans; Rats; Rats, Inbred F344; Receptors, Opioid, kappa; Reward; Spiro Compounds | 2002 |
Effects of cocaine on responding for ethanol or sucrose under a progressive ratio schedule.
Topics: Animals; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Drinking; Ethanol; Male; Rats; Reinforcement Schedule; Reward; Sucrose | 2002 |
CGP 44532, a GABAB receptor agonist, is hedonically neutral and reduces cocaine-induced enhancement of reward.
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Organophosphonates; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Reward | 2002 |
Cocaine-induced suppression of saccharin intake: a model of drug-induced devaluation of natural rewards.
Topics: Administration, Oral; Animals; Catheters, Indwelling; Cocaine; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Feeding Behavior; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Saccharin; Self Administration; Taste | 2002 |
Neurobiological evidence for hedonic allostasis associated with escalating cocaine use.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Drug Administration Schedule; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Hypothalamus; Male; Rats; Rats, Wistar; Reaction Time; Regression Analysis; Reward; Self Administration; Sensory Thresholds | 2002 |
Lack of reward and locomotor stimulation induced by heroin in mu-opioid receptor-deficient mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Female; Hallucinogens; Heroin; Male; Mice; Mice, Knockout; Motor Activity; Receptors, Opioid, mu; Reward | 2002 |
Cocaine and SKF-82958 potentiate brain stimulation reward in Swiss-Webster mice.
Topics: Animals; Benzazepines; Brain; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Reaction Time; Reward | 2002 |
Regulation of medial prefrontal cortex dopamine by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Motor Activity; Neostriatum; Neurons; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Reward; Stress, Physiological; Synaptic Transmission; Up-Regulation | 2002 |
Effect of cocaine and sucrose withdrawal period on extinction behavior, cue-induced reinstatement, and protein levels of the dopamine transporter and tyrosine hydroxylase in limbic and cortical areas in rats.
Topics: Animals; Cerebral Cortex; Cocaine; Conditioning, Operant; Cues; Dopamine Plasma Membrane Transport Proteins; Extinction, Psychological; Immunoblotting; Limbic System; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome; Sucrose; Tyrosine 3-Monooxygenase | 2002 |
Effects of the selective mu(1)-opioid receptor antagonist, naloxonazine, on cocaine-induced conditioned place preference and locomotor behavior in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward | 2002 |
Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats.
Topics: Animals; Behavior, Animal; Brain; Catalepsy; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Haloperidol; Male; Nitriles; Quinolines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Secondary Prevention; Self Administration; Spatial Behavior; Tetrahydroisoquinolines | 2002 |
The 5-HT3 antagonist Y-25130 blocks cocaine-induced lowering of ICSS reward thresholds in the rat.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; Hypothalamic Area, Lateral; Male; Medial Forebrain Bundle; Oxazines; Rats; Rats, Long-Evans; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reward; Self Stimulation; Serotonin Antagonists | 2003 |
The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Illicit Drugs; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Narcotics; Nicotine; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward | 2003 |
Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Extinction, Psychological; Gene Expression; Male; Nucleus Accumbens; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reward; RNA, Messenger; Stress, Physiological; Up-Regulation | 2003 |
Low dose cocaine self-administration transiently increases but high dose cocaine persistently decreases brain reward function in rats.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Motivation; Rats; Rats, Wistar; Reward; Self Administration; Self Stimulation; Time Factors | 2003 |
Dopamine D3 receptor ligands show place conditioning effect but do not influence cocaine-induced place preference.
Topics: Animals; Avoidance Learning; Benzazepines; Benzopyrans; Cocaine; Conditioning, Classical; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Indans; Male; Naphthalenes; Nitriles; Oxazines; Piperazines; Pyrrolidines; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Spatial Behavior; Substance-Related Disorders; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2003 |
Fluctuations in neural activity during cocaine self-administration: clues provided by brain thermorecording.
Topics: Animals; Body Temperature; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Energy Metabolism; Male; Motivation; Rats; Rats, Long-Evans; Reward; Self Administration | 2003 |
Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving.
Topics: Acoustic Stimulation; Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine; Drug Administration Routes; Extinction, Psychological; Limbic System; Male; Nerve Growth Factor; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance Withdrawal Syndrome; Sucrose; Time; Ventral Tegmental Area | 2003 |
Suppression of cocaine- and food-maintained behavior by the D2-like receptor partial agonist terguride in squirrel monkeys.
Topics: Animals; Behavior, Animal; Benzamides; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Food; Injections, Intravenous; Lisuride; Male; Motor Activity; Muscle Rigidity; Quinpirole; Receptors, Dopamine D2; Reinforcement Schedule; Reward; Saimiri | 2003 |
Effects of MDMA exposure on the conditioned place preference produced by other drugs of abuse.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Psychological; Drug Interactions; Ethanol; Hallucinogens; Heroin; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reward | 2003 |
Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward; Substance Withdrawal Syndrome; Synaptic Transmission | 2003 |
Sex differences in the conditioned rewarding effects of cocaine.
Topics: Adrenalectomy; Animals; Cocaine; Conditioning, Psychological; Corticosterone; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Inbred F344; Reward; Sex Characteristics | 2003 |
Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
Topics: Animals; Behavior, Animal; Cinnamates; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclopropanes; Dehydroepiandrosterone; Disease Susceptibility; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Finasteride; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnenolone; Progesterone; Receptors, sigma; Reward; Sigma-1 Receptor; Steroids | 2003 |
WIN 55,212-2 decreases the reinforcing actions of cocaine through CB1 cannabinoid receptor stimulation.
Topics: Algorithms; Animals; Benzoxazines; Brain; Cocaine; Conditioning, Operant; Electrodes, Implanted; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Reinforcement, Psychology; Reward; Rimonabant; Self Stimulation; Stimulation, Chemical | 2003 |
Methylphenidate and MDMA adolescent exposure in mice: long-lasting consequences on cocaine-induced reward and psychomotor stimulation in adulthood.
Topics: Age Factors; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Male; Methylphenidate; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Psychomotor Performance; Reward; Substance Withdrawal Syndrome; Time Factors; Weight Gain | 2003 |
Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses.
Topics: Analgesia; Animals; Behavior, Animal; Cocaine; Drug Synergism; Enkephalins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Threshold; Protein Precursors; Reaction Time; Receptors, Opioid, kappa; Reward; Spatial Behavior; Stress, Physiological; Swimming | 2003 |
Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core.
Topics: Amphetamine; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Motor Activity; Narcotics; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Oxidopamine; Rats; Rats, Long-Evans; Reward; Serotonin Plasma Membrane Transport Proteins; Spatial Behavior | 2003 |
Estrogen-dependent alterations in D2/D3-induced G protein activation in cocaine-sensitized female rats.
Topics: Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Brain; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Implants; Estradiol; Estrogens; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ovariectomy; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward; Sulfur Radioisotopes | 2003 |
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat.
Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Agonists; GABA-B Receptor Agonists; Male; Microdialysis; Morphine; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Receptors, GABA-B; Reward; Substance-Related Disorders; Synaptic Transmission; Up-Regulation | 2003 |
Gonadal hormones differentially modulate cocaine-induced conditioned place preference in male and female rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Biogenic Monoamines; Cesarean Section; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Psychological; Corticosterone; Drug Interactions; Estrogens; Exploratory Behavior; Female; Hormone Replacement Therapy; Male; Motor Activity; Nucleus Accumbens; Progesterone; Radioimmunoassay; Rats; Rats, Inbred F344; Reaction Time; Reward; Sex Characteristics; Time Factors; Ventral Tegmental Area | 2003 |
Persistent cue-evoked activity of accumbens neurons after prolonged abstinence from self-administered cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Discrimination Learning; Evoked Potentials, Auditory; Kinetics; Male; Neurons; Nucleus Accumbens; Rats; Rats, Long-Evans; Recurrence; Reward; Self Administration | 2003 |
Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Crosses, Genetic; Drug Administration Routes; Illicit Drugs; Immunotoxins; Male; Maze Learning; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Receptors, Neurokinin-1; Reward; Ribosome Inactivating Proteins, Type 1; Saporins; Spatial Behavior; Substance P | 2003 |
Involvement of the olfactory tubercle in cocaine reward: intracranial self-administration studies.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Choice Behavior; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Administration Routes; Male; Olfactory Pathways; Rats; Rats, Wistar; Receptors, Dopamine D1; Reinforcement, Psychology; Reward; Self Administration | 2003 |
Regulation of gene expression and cocaine reward by CREB and DeltaFosB.
Topics: Anesthetics, Local; Animals; Bacterial Proteins; Behavior, Addictive; Behavior, Animal; Cluster Analysis; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Gene Deletion; Gene Expression Regulation; Male; Mice; Mice, Transgenic; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; Time; Time Factors | 2003 |
Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Operant; Extinction, Psychological; Limbic System; Male; Motivation; Prefrontal Cortex; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward | 2003 |
Conditioned facilitation of brain reward function after repeated cocaine administration.
Topics: Animals; Brain; Cocaine; Conditioning, Psychological; Male; Rats; Rats, Wistar; Reward | 2003 |
Dorsal, but not ventral, hippocampal lesions disrupt cocaine place conditioning.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Denervation; Environment; Hippocampus; Male; Motivation; Neural Pathways; Orientation; Rats; Rats, Sprague-Dawley; Reward | 2003 |
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
Topics: Animals; Arrestins; Behavior, Animal; beta-Arrestin 2; beta-Arrestins; Cocaine; Corpus Striatum; Dopamine; Male; Mice; Mice, Knockout; Microdialysis; Morphine; Motor Activity; Reward; Spatial Behavior | 2003 |
Differential distribution of CREB in the mesolimbic dopamine reward pathway.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA; Dopamine; Dynorphins; Illicit Drugs; Limbic System; Mice; Mice, Mutant Strains; Morphine; Neural Pathways; Nucleus Accumbens; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Reward; Substance-Related Disorders; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2003 |
Acquisition of lever pressing for cocaine in C57BL/6J mice: effects of prior Pavlovian conditioning.
Topics: Animals; Catheterization; Cocaine; Conditioning, Classical; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Reward; Self Administration | 2003 |
Selective encoding of cocaine versus natural rewards by nucleus accumbens neurons is not related to chronic drug exposure.
Topics: Administration, Oral; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Drug Administration Schedule; Electrodes, Implanted; Injections, Intravenous; Male; Nerve Net; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Time; Water | 2003 |
Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Tobacco Use Disorder | 2003 |
Evidence for a relationship between Group 1 mGluR hypofunction and increased cocaine and ethanol sensitivity in Homer2 null mutant mice.
Topics: Animals; Carrier Proteins; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Ethanol; Excitatory Amino Acid Agonists; Homer Scaffolding Proteins; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Motor Activity; Neuronal Plasticity; Neuropeptides; Receptors, Metabotropic Glutamate; Reward; Substance-Related Disorders | 2003 |
Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dynorphins; Male; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; Neostriatum; Receptors, Opioid, kappa; Reward | 2004 |
Blockade of substantia nigra dopamine D1 receptors reduces intravenous cocaine reward in rats.
Topics: Animals; Benzazepines; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dendrites; Dopamine; Dopamine Antagonists; Injections, Intravenous; Male; Microinjections; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reinforcement, Psychology; Reward; Self Administration; Substantia Nigra; Time Factors | 2004 |
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disks Large Homolog 4 Protein; Dopamine; Down-Regulation; Guanylate Kinases; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Potentiation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Neural Pathways; Neuronal Plasticity; Nucleus Accumbens; Presynaptic Terminals; Reward; RNA, Messenger; Synaptic Transmission | 2004 |
Rewarding effects elicited by cocaine microinjections into the ventral tegmental area of C57BL/6 mice: involvement of dopamine D1 and serotonin1B receptors.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred C57BL; Microinjections; Oxadiazoles; Piperazines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Dopamine D1; Reward; Self Administration; Serotonin Antagonists; Spatial Behavior; Ventral Tegmental Area | 2004 |
A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Environment; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Ventral Tegmental Area | 2004 |
Differential effects of dopaminergic agents on locomotor sensitisation and on the reinstatement of cocaine-seeking and food-seeking behaviour.
Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Agonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Feeding Behavior; Male; Motor Activity; Photic Stimulation; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Recurrence; Reward; Tetrahydronaphthalenes | 2004 |
A critical role for beta-endorphin in cocaine-seeking behavior.
Topics: Animals; Antibodies, Blocking; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2004 |
Self-administration of fentanyl, cocaine and ketamine: effects on the pituitary-adrenal axis in rhesus monkeys.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fentanyl; Hydrocortisone; Ketamine; Macaca mulatta; Male; Pituitary-Adrenal System; Reinforcement Schedule; Reward; Self Administration | 2004 |
Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer.
Topics: Amino Acids; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Reward; Secondary Prevention; Self Administration | 2004 |
The role of D1 and D2 receptors in the cocaine conditioned place preference of male and female rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Male; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Sex Factors | 2004 |
Ethological analyses of crayfish behavior: a new invertebrate system for measuring the rewarding properties of psychostimulants.
Topics: Amphetamine; Analysis of Variance; Animals; Astacoidea; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Locomotion; Reward; Spatial Behavior; Stimulation, Chemical; Time Factors | 2004 |
The basolateral complex of the amygdala mediates the modulation of intracranial self-stimulation threshold by drug-associated cues.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Discrimination Learning; Male; Morphine; Rats; Rats, Long-Evans; Reward; Self Stimulation | 2004 |
Cocaine, but not alcohol, reinstates cocaine-induced place preferences.
Topics: Animals; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Ethanol; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Reward | 2004 |
Neuroscience. Addicted rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cues; Electroshock; Humans; Models, Animal; Motivation; Rats; Reward; Self Administration; Time Factors | 2004 |
Evidence for addiction-like behavior in the rat.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cues; Electroshock; Humans; Male; Models, Animal; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors | 2004 |
Drug seeking becomes compulsive after prolonged cocaine self-administration.
Topics: Animals; Appetitive Behavior; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Electroshock; Fear; Male; Models, Animal; Rats; Reinforcement, Psychology; Reward; Self Administration; Sucrose; Time Factors | 2004 |
CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors.
Topics: Alcohol Drinking; Animals; Anti-Anxiety Agents; Benzazepines; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Dextroamphetamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Ethanol; Mice; Mice, Knockout; Motor Activity; Neostriatum; Quinpirole; Raclopride; Radioligand Assay; Receptor, Cannabinoid, CB1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2005 |
The effects of cocaine on the rate independent brain stimulation reward threshold in the mouse.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Reward | 2004 |
Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats.
Topics: Acetaldehyde; Adolescent; Age Factors; Aging; Animals; Brain; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Nicotiana; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement, Psychology; Reward; Self Administration; Tobacco Use Disorder | 2005 |
Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine.
Topics: Animals; Body Weight; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Learning; Male; Morphine; Motor Activity; Narcotic Antagonists; Narcotics; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reward | 2004 |
Natural reward-related learning in rats with neonatal ventral hippocampal lesions and prior cocaine exposure.
Topics: Animals; Animals, Newborn; Cocaine; Conditioning, Operant; Excitatory Amino Acid Agonists; Female; Hippocampus; Ibotenic Acid; Learning; Male; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward | 2005 |
Comparison of the reinforcing effects of cocaine and cocaine/heroin combinations under progressive ratio and choice schedules in rats.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Synergism; Heroin; Male; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration | 2005 |
Effect of MS-153, a glutamate transporter activator, on the conditioned rewarding effects of morphine, methamphetamine and cocaine in mice.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Methamphetamine; Mice; Morphine; Motor Activity; Narcotics; Nicotinic Acids; Reward; Time Factors | 2005 |
Effects of the mixed-action kappa/mu opioid agonist 8-carboxamidocyclazocine on cocaine- and food-maintained responding in rhesus monkeys.
Topics: Animals; Cocaine; Conditioning, Operant; Cyclazocine; Dose-Response Relationship, Drug; Female; Food; Hypnotics and Sedatives; Macaca mulatta; Male; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement Schedule; Reward; Vomiting | 2004 |
Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats.
Topics: Animals; Brain; Choice Behavior; Cocaine; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Male; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Self Administration; Self Stimulation | 2005 |
Effects of deletion of gria1 or gria2 genes encoding glutamatergic AMPA-receptor subunits on place preference conditioning in mice.
Topics: Amygdala; Animals; Choice Behavior; Cocaine; Conditioning, Classical; Food; Mice; Mice, Knockout; Receptors, AMPA; Reward | 2005 |
Pup suckling is more rewarding than cocaine: evidence from functional magnetic resonance imaging and three-dimensional computational analysis.
Topics: Animals; Animals, Suckling; Brain; Brain Mapping; Cocaine; Dopamine; Female; Image Processing, Computer-Assisted; Injections, Intraventricular; Lactation; Magnetic Resonance Imaging; Maternal Behavior; Neural Pathways; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2005 |
Evidence that the relations between novelty-induced activity, locomotor stimulation and place preference induced by cocaine qualitatively depend upon the dose: a multiple regression analysis in inbred C57BL/6J mice.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Environment; Male; Mice; Mice, Inbred C57BL; Motor Activity; Regression Analysis; Reward; Stimulation, Chemical | 2005 |
Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function.
Topics: Adaptation, Physiological; Algorithms; Animals; Cocaine; Computer Simulation; Neural Networks, Computer; Reinforcement, Psychology; Reward; Self Administration; Substance-Related Disorders | 2005 |
The subthalamic nucleus exerts opposite control on cocaine and 'natural' rewards.
Topics: Animals; Appetitive Behavior; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; GABA Agonists; Male; Muscimol; Rats; Rats, Long-Evans; Rats, Wistar; Reinforcement Schedule; Reward; Statistics, Nonparametric; Subthalamic Nucleus; Time Factors | 2005 |
The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Baclofen; Behavior, Animal; Cocaine; Cyclopentanes; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation | 2005 |
Prazosin, an alpha-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Prazosin; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement Schedule; Reward | 2005 |
Blockade of melanocortin transmission inhibits cocaine reward.
Topics: Agouti Signaling Protein; alpha-MSH; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleus Accumbens; Protein Precursors; Rats; Rats, Mutant Strains; Receptor, Melanocortin, Type 4; Reward; RNA, Messenger; Self Administration; Time Factors | 2005 |
Real time computation of in vivo drug levels during drug self-administration experiments.
Topics: Algorithms; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Computer Systems; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Models, Statistical; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Software; Substance-Related Disorders; Syringes | 2005 |
Cocaine up-regulates Fra-2 and sigma-1 receptor gene and protein expression in brain regions involved in addiction and reward.
Topics: Actins; Animals; Blotting, Western; Brain; Brain Chemistry; Cocaine; DNA-Binding Proteins; DNA, Complementary; Fos-Related Antigen-2; Male; Mice; Motor Activity; Oligonucleotide Array Sequence Analysis; Piperazines; Receptors, sigma; Reverse Transcriptase Polymerase Chain Reaction; Reward; Sigma-1 Receptor; Substance-Related Disorders; Transcription Factor AP-1; Transcription Factors; Up-Regulation | 2005 |
Conditioned rewarding stimulus associated with cocaine self-administration reverses the depression of catecholamine brain systems following cocaine withdrawal in rats.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine; Extinction, Psychological; Male; Norepinephrine; Rats; Rats, Wistar; Reward; Serotonin; Substance Withdrawal Syndrome | 2006 |
Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Female; Green Fluorescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Narcotics; Neurons; Nucleus Accumbens; Receptors, AMPA; Recombinant Fusion Proteins; Reward; Transcription, Genetic; Tyrosine 3-Monooxygenase; Up-Regulation; Ventral Tegmental Area | 2005 |
Mu-opioid receptor and CREB activation are required for nicotine reward.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Blotting, Northern; Blotting, Western; Brain; Cell Count; Cocaine; Conditioning, Operant; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Narcotic Antagonists; Neurons; Nicotine; Phosphorylation; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Reward; RNA, Messenger; Time Factors; Tobacco Use Disorder | 2005 |
Regulation of dopaminergic transmission and cocaine reward by the Clock gene.
Topics: Animals; Blotting, Western; Brain; Circadian Rhythm; CLOCK Proteins; Cocaine; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Homozygote; Immunohistochemistry; Male; Mice; Mice, Transgenic; Models, Neurological; Mutation; Neurons; Oligonucleotide Array Sequence Analysis; Phenotype; Phosphorylation; Point Mutation; Reward; Substance-Related Disorders; Time Factors; Trans-Activators; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2005 |
Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference.
Topics: Amino Acid Substitution; Amphetamine; Animals; Brain; Central Nervous System Stimulants; Chromosomes, Artificial, P1 Bacteriophage; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine; Exploratory Behavior; Glutamic Acid; Locomotion; Mice; Mutation, Missense; Neurons; Point Mutation; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Reward | 2005 |
Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats.
Topics: Amphetamine; Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Feeding Behavior; Locomotion; Male; N-Methyl-3,4-methylenedioxyamphetamine; Pyridines; Rats; Rats, Sprague-Dawley; Reward; Serotonin Agents | 2005 |
The lack of A2A adenosine receptors diminishes the reinforcing efficacy of cocaine.
Topics: Adenosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Male; Mice; Mice, Knockout; Motor Activity; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration | 2006 |
NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice.
Topics: Amphetamine-Related Disorders; Animals; Blotting, Northern; Brain Chemistry; Cell Adhesion Molecules; Chromosome Mapping; Cloning, Molecular; Cocaine; Cocaine-Related Disorders; DNA, Complementary; Gene Expression Regulation; Genome, Human; Genotype; Haplotypes; Humans; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Substance-Related Disorders | 2006 |
The many facets of the locomotor response to a novel environment test: theoretical comment on Mitchell, Cunningham, and Mark (2005).
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Exploratory Behavior; Generalization, Psychological; Motor Activity; Reward; Self Administration; Time Factors | 2005 |
Deletion of dopamine D1 and D3 receptors differentially affects spontaneous behaviour and cocaine-induced locomotor activity, reward and CREB phosphorylation.
Topics: Animals; Behavior, Animal; Blotting, Western; Cell Count; Cocaine; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Phosphorylation; Receptors, Dopamine D1; Receptors, Dopamine D3; Reward; Time Factors | 2005 |
The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Extinction, Psychological; Fluorenes; Male; Piperazines; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration | 2006 |
Perinatal protein malnutrition enhances rewarding cocaine properties in adult rats.
Topics: Animals; Animals, Newborn; Brain; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Protein-Energy Malnutrition; Proto-Oncogene Proteins c-fos; Rats; Reward | 2006 |
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Intracellular Signaling Peptides and Proteins; Male; Models, Statistical; Naphthyridines; Neuropeptides; Orexins; Rats; Rats, Wistar; Reward; Self Administration; Time Factors; Urea | 2005 |
Differences in impulsivity and risk-taking propensity between primary users of crack cocaine and primary users of heroin in a residential substance-use program.
Topics: Age Factors; Analysis of Variance; Behavioral Research; Cocaine-Related Disorders; Crack Cocaine; District of Columbia; Female; Heroin; Heroin Dependence; Humans; Impulsive Behavior; Male; Residential Treatment; Reward; Risk-Taking; Sex Factors; Surveys and Questionnaires; Urban Population | 2005 |
AMPA-receptor GluR1 subunits are involved in the control over behavior by cocaine-paired cues.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Extinction, Psychological; Glutamic Acid; Learning; Male; Mice; Mice, Knockout; Reaction Time; Receptors, AMPA; Reinforcement, Psychology; Reward; Self Administration; Synaptic Transmission | 2007 |
Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration.
Topics: Animals; Behavior, Addictive; Brain; Chronic Disease; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Hyperkinesis; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Substance Withdrawal Syndrome | 2007 |
Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI.
Topics: Algorithms; Anesthesia; Animals; Blood Volume; Brain Chemistry; Cerebrovascular Circulation; Cocaine; Data Interpretation, Statistical; Hemodynamics; Hypercapnia; Injections, Intravenous; Magnetic Resonance Imaging; Male; Metabolism; Oxygen; Rats; Rats, Sprague-Dawley; Reward | 2006 |
Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool.
Topics: alpha-Methyltyrosine; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Medial Forebrain Bundle; Mice; Mice, Knockout; Neostriatum; Presynaptic Terminals; Reward; Synapsins; Synaptic Transmission; Synaptic Vesicles; Up-Regulation; Ventral Tegmental Area | 2006 |
Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration.
Topics: Animals; Anxiety Disorders; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Septal Nuclei; Stress, Psychological; Synaptic Transmission | 2006 |
Elevation of glucocorticoids is necessary but not sufficient for the escalation of cocaine self-administration by chronic electric footshock stress in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Chronic Disease; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroshock; Male; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological; Up-Regulation | 2007 |
Acute and repeated cocaine induces alterations in FosB/DeltaFosB expression in the paraventricular nucleus of the hypothalamus.
Topics: Adaptation, Physiological; Animals; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hypothalamo-Hypophyseal System; Male; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine; Reward; Transcriptional Activation; Up-Regulation | 2006 |
Prenatal cocaine alters later responses to morphine in adult male mice.
Topics: Aggression; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cocaine; Conditioning, Operant; Exploratory Behavior; Female; Interpersonal Relations; Male; Mice; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reward | 2006 |
Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter.
Topics: Animals; Brain; Cocaine; Conditioning, Psychological; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gene Targeting; In Vitro Techniques; Mice; Mice, Transgenic; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Patch-Clamp Techniques; Reward | 2006 |
The role of the basolateral amygdala in stimulus-reward memory and extinction memory consolidation and in subsequent conditioned cued reinstatement of cocaine seeking.
Topics: Amygdala; Animals; Cocaine; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Injections, Intraventricular; Male; Memory; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Sodium Channels; Tetrodotoxin | 2006 |
Development of peptidic dopamine transporter inhibitors via aromatic modification-mediated conformational restriction.
Topics: Animals; Benzoates; Binding Sites; Biphenyl Compounds; Central Nervous System Stimulants; CHO Cells; Cocaine; Conditioning, Psychological; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Mice; Motor Activity; Naphthalenes; Oligopeptides; Protein Structure, Secondary; Radioligand Assay; Rats; Reward; Structure-Activity Relationship | 2006 |
Renewal effect: context-dependent extinction of a cocaine- and a morphine-induced conditioned floor preference.
Topics: Animals; Association Learning; Choice Behavior; Cocaine; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Injections, Intraperitoneal; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Social Environment | 2006 |
Differential ability of D1 and D2 dopamine receptor agonists to induce and modulate expression and reinstatement of cocaine place preference in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Agonists; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward; Self Administration | 2007 |
An endogenous neuroprotectant substance, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), prevents the behavioral and neurochemical effects of cocaine reinstatement in drug-dependent rats.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Limbic System; Male; Neural Pathways; Neuroprotective Agents; Norepinephrine; Rats; Reward; Secondary Prevention; Self Administration; Serotonin; Substance Withdrawal Syndrome; Tetrahydroisoquinolines; Ventral Tegmental Area | 2007 |
Noradrenaline is necessary for the hedonic properties of addictive drugs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Appetitive Behavior; Benzazepines; Biphenyl Compounds; Bupropion; Carbidopa; Cocaine; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Droxidopa; Female; Genotype; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Reward; Substance-Related Disorders | 2006 |
Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Recurrence; Reward | 2006 |
Expression of cocaine-induced conditioned place preference in apomorphine susceptible and unsusceptible rats.
Topics: Animals; Apomorphine; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Wistar; Reward; Species Specificity | 2006 |
Gestational exposure to cocaine alters cocaine reward.
Topics: Animals; Association Learning; Avoidance Learning; Brain; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Dose-Response Relationship, Drug; Female; Mice; Motivation; Orientation; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Social Environment | 2006 |
"Tasting and wasting" behavior in non-human primates: aberrant behavior or normal behavior in "times of plenty".
Topics: Animals; Appetitive Behavior; Candy; Conditioning, Operant; Energy Intake; Feeding Behavior; Female; Food Preferences; Male; Papio; Reward; Sex Factors; Taste | 2006 |
Adolescents differ from adults in cocaine conditioned place preference and cocaine-induced dopamine in the nucleus accumbens septi.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Data Interpretation, Statistical; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2006 |
Injection of oxotremorine in nucleus accumbens shell reduces cocaine but not food self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Feeding Behavior; Male; Microinjections; Muscarinic Agonists; Nucleus Accumbens; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reward; Self Administration | 2006 |
Anxiolytic-like actions of buspirone in a runway model of intravenous cocaine self-administration.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Cocaine; Injections, Intravenous; Male; Rats; Reward; Self Administration; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists | 2006 |
The psychostimulant and rewarding effects of cocaine in histidine decarboxylase knockout mice do not support the hypothesis of an inhibitory function of histamine on reward.
Topics: Animals; Arousal; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Exploratory Behavior; Genotype; Histamine; Histidine Decarboxylase; Hypothalamic Area, Lateral; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Motivation; Motor Activity; Neural Inhibition; Reward | 2007 |
Biphasic alterations in serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Male; Motor Activity; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Reward; Self Administration; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Synaptic Transmission; Ventral Tegmental Area | 2006 |
Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Environment, Controlled; Lidocaine; Male; Neural Pathways; Odorants; Photic Stimulation; Prefrontal Cortex; Rats; Reward; Self Administration | 2006 |
Evaluation of reward processes in an animal model of depression.
Topics: Animals; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Cocaine; Depression; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Food Preferences; Locomotion; Male; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Self Stimulation; Sensory Thresholds; Sucrose; Time Factors | 2007 |
Previous cocaine exposure makes rats hypersensitive to both delay and reward magnitude.
Topics: Animals; Choice Behavior; Cocaine; Male; Rats; Rats, Long-Evans; Reward; Task Performance and Analysis; Time Factors | 2007 |
The effects of a single exposure to uncontrollable stress on the subsequent conditioned place preference responses to oxycodone, cocaine, and ethanol in rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroshock; Ethanol; Injections, Subcutaneous; Male; Motor Activity; Oxycodone; Rats; Rats, Sprague-Dawley; Restraint, Physical; Reward; Stress, Psychological; Tail; Time Factors | 2007 |
The effects of a single session of inescapable tailshock on the subsequent locomotor response to brief footshock and cocaine administration in rats.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroshock; Injections, Intraperitoneal; Male; Motor Activity; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Restraint, Physical; Reward; Stress, Psychological; Tail | 2007 |
Behavioral effects of morphine and cocaine in M1 muscarinic acetylcholine receptor-deficient mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Muscarinic Antagonists; Pain Measurement; Pain Threshold; Pirenzepine; Receptor, Muscarinic M1; Reward | 2007 |
Runway self-administration of intracerebroventricular cocaine: evidence of mixed positive and negative drug actions.
Topics: Animals; Arousal; Avoidance Learning; Brain; Central Nervous System Stimulants; Cocaine; Conflict, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Running; Self Administration; Social Environment | 2007 |
Differential effects of sigma1 receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylenediamines; Food Preferences; Male; Milk; Rats; Rats, Wistar; Receptors, sigma; Reward; Self Administration | 2007 |
Effects of serotonin 5-HT1B receptor ligands on the cocaine- and food-maintained self-administration in rats.
Topics: Animals; Behavior, Animal; Benzamides; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Injections, Intravenous; Ligands; Male; Motor Activity; Oxadiazoles; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Reinforcement Schedule; Reward; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists | 2007 |
Environmental modulation of cocaine self-administration in the rat.
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Infusions, Intravenous; Male; Motivation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration | 2007 |
A critical transition in cocaine self-administration: behavioral and neurobiological implications.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Models, Theoretical; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration | 2007 |
Increased accumbens Cdk5 expression in rats after short-access to self-administered cocaine, but not after long-access sessions.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cyclin-Dependent Kinase 5; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Tolerance; Enzyme Activation; Male; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors; Up-Regulation; Ventral Tegmental Area | 2007 |
Tranylcypromine enhancement of nicotine self-administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Half-Life; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Self Administration; Tranylcypromine | 2007 |
Blocking of conditioning to a cocaine-paired stimulus: testing the hypothesis that cocaine perpetually produces a signal of larger-than-expected reward.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Male; Models, Psychological; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration | 2007 |
Experience-dependent effects of cocaine self-administration/conditioning on prefrontal and accumbens dopamine responses.
Topics: Animals; Calibration; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine; Dopamine Uptake Inhibitors; Food; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2007 |
Impulsivity (delay discounting) for food and cocaine in male and female rats selectively bred for high and low saccharin intake.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Eating; Female; Food Preferences; Impulsive Behavior; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Saccharin; Sex Characteristics | 2007 |
5-HT(1B) receptors in nucleus accumbens efferents enhance both rewarding and aversive effects of cocaine.
Topics: Animals; Avoidance Learning; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Genetic Vectors; Injections, Intraperitoneal; Male; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Reward; Serotonin; Synaptic Transmission; Transfection | 2007 |
Compulsive drug seeking by rats under punishment: effects of drug taking history.
Topics: Anesthetics, Local; Animals; Animals, Outbred Strains; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Electroshock; Fear; Feeding Behavior; Male; Punishment; Rats; Reinforcement Schedule; Reward; Self Administration; Solutions; Sucrose; Time Factors | 2007 |
Corticosterone fails to produce conditioned place preference or conditioned place aversion in rats.
Topics: Animals; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Corticosterone; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Exploratory Behavior; Hormones; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward | 2007 |
Effects of buspirone on the immediate positive and delayed negative properties of intravenous cocaine as measured in the conditioned place preference test.
Topics: Animals; Anxiety; Buspirone; Cocaine; Conditioning, Operant; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reward; Serotonin; Serotonin Receptor Agonists; Synapses | 2007 |
Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward function.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Gene Expression Regulation; Male; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome; Systole | 2007 |
Prenatal exposure to cocaine increases the rewarding potency of cocaine and selective dopaminergic agonists in adult mice.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Female; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Self Stimulation; Sex Factors | 2008 |
Foster mother care but not prenatal morphine exposure enhances cocaine self-administration in young adult male and female rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Estrous Cycle; Female; Male; Maternal Behavior; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Sex Factors; Sodium Chloride; Sucrose | 2007 |
Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Locomotion; Male; Mice; Mice, Transgenic; Reward | 2007 |
Effects of stress during reactivation on rewarding memory.
Topics: Anesthetics, Local; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Male; Memory; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological; Sucrose | 2007 |
Cocaine exposure causes long-term increases in impulsive choice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Impulsive Behavior; Male; Motor Activity; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Time Factors | 2007 |
Prenatal exposure of bupropion may enhance agitation, anxiety responses, and sensitivity to cocaine effects in adult mice.
Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Anxiety; Bupropion; Cocaine; Dose-Response Relationship, Drug; Female; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Agitation; Reward | 2007 |
Differential effects of self-administered cocaine in adolescent and adult rats on stimulus-reward learning.
Topics: Age Factors; Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Infusions, Intravenous; Learning; Male; Memory; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration | 2007 |
NMDA receptor blockade in the basolateral amygdala disrupts consolidation of stimulus-reward memory and extinction learning during reinstatement of cocaine-seeking in an animal model of relapse.
Topics: Amygdala; Animals; Appetitive Behavior; Association Learning; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward | 2007 |
Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Indoles; Male; Motor Activity; Nucleus Accumbens; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reward; Serotonin Antagonists; Simplexvirus; Time Factors; Up-Regulation | 2008 |
Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Fetal Nutrition Disorders; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Stress, Psychological | 2007 |
A role for BDNF in cocaine reward and relapse.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Humans; Nucleus Accumbens; Recurrence; Reward | 2007 |
Conditioned drug reward enhances subsequent spatial learning and memory in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Male; Maze Learning; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior | 2007 |
Intense sweetness surpasses cocaine reward.
Topics: Animals; Cocaine; Conditioning, Operant; Corpus Striatum; Diet; Dopamine; Dopamine Uptake Inhibitors; Food Preferences; Humans; Locomotion; Male; Meta-Analysis as Topic; Pleasure; Rats; Rats, Wistar; Reward; Saccharin; Substance-Related Disorders; Sweetening Agents; Taste; Taste Perception | 2007 |
Overexpression of plasminogen activators in the nucleus accumbens enhances cocaine-, amphetamine- and morphine-induced reward and behavioral sensitization.
Topics: Amphetamine; Animals; Base Sequence; Behavior, Animal; Cocaine; DNA Primers; Doxycycline; Lentivirus; Male; Molecular Sequence Data; Morphine; Nucleus Accumbens; Plasminogen Activators; Polymerase Chain Reaction; Rats; Rats, Wistar; Reward; RNA, Small Interfering; RNA, Viral; Tissue Plasminogen Activator; Viral Proteins | 2008 |
A role for mu opioid receptors in cocaine-induced activity, sensitization, and reward in the rat.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Motor Activity; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Somatostatin | 2007 |
Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization.
Topics: Animals; Appetitive Behavior; Association Learning; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Classical; Cues; Dopamine; Dopamine Uptake Inhibitors; Individuality; Logistic Models; Male; Motivation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reward; Statistics, Nonparametric | 2008 |
Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Reinforcement Schedule; Reward; Rimonabant; Self Administration | 2008 |
The effects of concurrent administration of +/-3,4-methylenedioxymethamphetamine and cocaine on conditioned place preference in the adult male rat.
Topics: Animals; Body Weight; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Serotonin | 2007 |
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Berberine Alkaloids; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Stereoisomerism | 2007 |
Specific blockade of morphine- and cocaine-induced reinforcing effects in conditioned place preference by nitrous oxide in mice.
Topics: Analgesics, Opioid; Animals; Anxiety; Cocaine; Conditioning, Operant; Food Preferences; Male; Memory; Mice; Morphine; Motor Activity; Nitrous Oxide; Recognition, Psychology; Reinforcement, Psychology; Reward; Swimming | 2007 |
A stimulus-control account of regulated drug intake in rats.
Topics: Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Cues; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Light; Male; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Reward; Self Administration | 2008 |
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.
Topics: Acetylation; Adaptation, Physiological; Animals; Chromatin; Chronic Disease; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Emotions; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Histone Deacetylases; Histones; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Stress, Psychological | 2007 |
Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin.
Topics: Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Fluoxetine; Male; Mice; Mice, Knockout; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission | 2007 |
Cdk5 modulates cocaine reward, motivation, and striatal neuron excitability.
Topics: Animals; Cocaine; Corpus Striatum; Cyclin-Dependent Kinase 5; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motivation; Motor Activity; Neurons; Reward | 2007 |
The influence of subthalamic nucleus lesions on sign-tracking to stimuli paired with food and drug rewards: facilitation of incentive salience attribution?
Topics: Animals; Attention; Axotomy; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Denervation; Dopamine Uptake Inhibitors; Eye Movements; Feeding Behavior; Impulsive Behavior; Male; Motivation; Neural Pathways; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders; Subthalamic Nucleus | 2008 |
Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Exploratory Behavior; Extinction, Psychological; GABA Agents; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Vigabatrin | 2008 |
Progesterone attenuates cocaine-induced conditioned place preference in female rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Female; Learning; Memory Disorders; Menstrual Cycle; Neuropsychological Tests; Progesterone; Rats; Rats, Inbred F344; Recognition, Psychology; Recurrence; Reward; Sex Characteristics | 2008 |
The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Benzimidazoles; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Receptors, Opioid; Reward; Time Factors | 2008 |
Repeated electrical stimulation of reward-related brain regions affects cocaine but not "natural" reinforcement.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Electric Stimulation; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration | 2007 |
The role of beta-endorphin in the acute motor stimulatory and rewarding actions of cocaine in mice.
Topics: Animals; Association Learning; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Crosses, Genetic; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Genetic Carrier Screening; Genotype; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Morphine; Motivation; Motor Activity; Pro-Opiomelanocortin; Reward; Social Environment | 2008 |
Effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline on the behavioral effects of cocaine in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Feeding Behavior; Male; Motor Activity; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Tetrahydroisoquinolines | 2007 |
Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans.
Topics: Adolescent; Adult; Aged; Amphetamine; Amphetamine-Related Disorders; Appetitive Behavior; Association Learning; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Humans; Male; Middle Aged; Motivation; Opioid-Related Disorders; Probability Learning; Receptors, Serotonin; Reversal Learning; Reward; Stereotyped Behavior | 2008 |
Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors.
Topics: Acetylation; Animals; Brain; Brain Chemistry; Brain-Derived Neurotrophic Factor; Chromatin Assembly and Disassembly; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine D1; Reward; Signal Transduction; Synaptic Transmission; Tyrosine 3-Monooxygenase | 2008 |
Competition between the conditioned rewarding effects of cocaine and novelty.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Exploratory Behavior; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward | 2008 |
Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat.
Topics: Adrenal Glands; Animals; Blotting, Western; Caloric Restriction; Cocaine; Corticosterone; Darkness; Dose-Response Relationship, Drug; Light; Male; Motor Activity; Nucleus Accumbens; Organ Size; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Thymus Gland | 2008 |
Cocaine-like neurochemical effects of antihistaminic medications.
Topics: Animals; Central Nervous System Stimulants; Chlorpheniramine; Cocaine; Diphenhydramine; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Histamine H1 Antagonists; Male; Nucleus Accumbens; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Reward; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Substance-Related Disorders; Synaptic Transmission; Synaptosomes; Triprolidine | 2008 |
Enhancement of endocannabinoid neurotransmission through CB1 cannabinoid receptors counteracts the reinforcing and psychostimulant effects of cocaine.
Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Endocannabinoids; Male; Morpholines; Motor Activity; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Stimulation; Synaptic Transmission | 2008 |
Wheel-running behavior is altered following withdrawal from repeated cocaine in adult rats.
Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Exploratory Behavior; Habituation, Psychophysiologic; Male; Motivation; Motor Activity; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Statistics, Nonparametric; Substance Withdrawal Syndrome | 2008 |
D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats.
Topics: Adenoviridae; Animals; Cocaine; Cocaine-Related Disorders; DNA; Dopamine; Dopamine Uptake Inhibitors; Gene Transfer Techniques; Genetic Vectors; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reward; Self Administration; Treatment Outcome; Up-Regulation | 2008 |
Social reward-conditioned place preference: a model revealing an interaction between cocaine and social context rewards in rats.
Topics: Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Classical; Conditioning, Operant; Extinction, Psychological; Models, Biological; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Social Behavior; Social Environment; Spatial Behavior; Substance-Related Disorders | 2008 |
Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Immunohistochemistry; Injections, Intraventricular; Male; Nucleus Accumbens; Peptide Fragments; Proto-Oncogene Proteins c-fos; Psychomotor Agitation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Somatostatin; Ventral Tegmental Area | 2008 |
Fishbowls and candy bars: using low-cost incentives to increase treatment retention.
Topics: Candy; Goals; Humans; Reward; Substance Abuse Treatment Centers; Substance-Related Disorders; Urinalysis | 2003 |
Comparison of dopamine D1 and D5 receptor knockout mice for cocaine locomotor sensitization.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward; Stereotyped Behavior | 2008 |
The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward.
Topics: Analysis of Variance; Animals; Benzeneacetamides; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Electric Stimulation; Male; Medial Forebrain Bundle; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Time Factors | 2008 |
The hippocampal dentate gyrus is essential for generating contextual memories of fear and drug-induced reward.
Topics: Analysis of Variance; Animals; Association Learning; Central Nervous System Agents; Cocaine; Conditioning, Classical; Dentate Gyrus; Exploratory Behavior; Fear; Hippocampus; Male; Rats; Rats, Long-Evans; Retention, Psychology; Reward | 2008 |
Cocaine but not natural reward self-administration nor passive cocaine infusion produces persistent LTP in the VTA.
Topics: Animals; Cocaine; Conditioning, Operant; Infusions, Parenteral; Long-Term Potentiation; Male; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ventral Tegmental Area | 2008 |
Human behaviour: Share and share alike.
Topics: Altruism; Animals; Candy; Child; Child, Preschool; Female; Humans; Infant; Male; Pan troglodytes; Reward; Social Justice | 2008 |
Potentiation of intracranial self-stimulation during prolonged subcutaneous infusion of cocaine.
Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Subcutaneous; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors | 2008 |
Acetylcholine release in the mesocorticolimbic dopamine system during cocaine seeking: conditioned and unconditioned contributions to reward and motivation.
Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Behavior, Animal; Cholinergic Antagonists; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Extinction, Psychological; Male; Mecamylamine; Microdialysis; Motivation; Rats; Rats, Long-Evans; Reward; Self Administration; Substantia Nigra; Ventral Tegmental Area | 2008 |
Novelty-induced locomotion is positively associated with cocaine ingestion in adolescent rats; anxiety is correlated in adults.
Topics: Aging; Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Environment; Female; Male; Motor Activity; Pharmaceutical Solutions; Rats; Reward; Sex Characteristics | 2009 |
Anxiety increases the place conditioning induced by cocaine in rats.
Topics: Analysis of Variance; Animals; Anxiety; Association Learning; Avoidance Learning; Cocaine; Conditioning, Psychological; Exploratory Behavior; Injections, Intraperitoneal; Maze Learning; Mice; Rats; Rats, Wistar; Reward; Stimulation, Chemical | 2009 |
Neuroscience: Brain's defence against cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dendrites; Humans; Myogenic Regulatory Factors; Neuronal Plasticity; Phosphorylation; Reward; Synapses; Transcription Factors | 2008 |
Amphetamine- and cocaine-induced conditioned place preference and concomitant psychomotor sensitization in mice with genetically inactivated melanin-concentrating hormone MCH(1) receptor.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Psychomotor Performance; Receptors, Somatostatin; Reward | 2008 |
Regulation of synaptic connectivity with chronic cocaine.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dendritic Spines; Disease Models, Animal; Gene Expression; Humans; MEF2 Transcription Factors; Myogenic Regulatory Factors; Neuronal Plasticity; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward; Signal Transduction; Synaptic Transmission | 2008 |
Cocaine does not produce reward in absence of dopamine transporter inhibition.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reward | 2009 |
Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Integrases; Male; Mice; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, trkB; Reward; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2009 |
Differential effects of methamphetamine and cocaine on conditioned place preference and locomotor activity in adult and adolescent male rats.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2009 |
Sensitivity to cocaine conditioned reward depends on sex and age.
Topics: Aging; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Reward; Sex Characteristics | 2009 |
Cocaine disinhibits dopamine neurons in the ventral tegmental area via use-dependent blockade of GABA neuron voltage-sensitive sodium channels.
Topics: Action Potentials; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Methamphetamine; Neural Inhibition; Neurons; Rats; Rats, Wistar; Receptors, Dopamine D2; Reward; Sodium Channel Blockers; Sodium Channels; Synaptic Transmission; Ventral Tegmental Area | 2008 |
Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.
Topics: Animals; Biogenic Monoamines; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dopamine Uptake Inhibitors; Food; Macaca mulatta; Male; Norepinephrine; Phenmetrazine; Piperazines; Piperidines; Reward; Serotonin; Synaptosomes | 2009 |
Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism.
Topics: Administration, Oral; Animals; Behavior, Animal; Benzhydryl Compounds; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; gamma-Aminobutyric Acid; Globus Pallidus; GluK3 Kainate Receptor; Male; Microdialysis; Motor Activity; Rats; Rats, Long-Evans; Receptors, Kainic Acid; Reinforcement Schedule; Reward; Self Administration; Sucrose; Sweetening Agents | 2009 |
Bees may enjoy coke.
Topics: Animal Feed; Animals; Bees; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Insecticides; Motor Activity; Pollen; Reward; Sucrose | 2009 |
The effects of medial prefrontal cortex infusions of cocaine in a runway model of drug self-administration: evidence of reinforcing but not anxiogenic actions.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Male; Microinjections; Motivation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Running; Self Administration | 2009 |
Dopamine transporters, D2 receptors, and dopamine release in generalized social anxiety disorder.
Topics: Adult; Carbon Radioisotopes; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Image Processing, Computer-Assisted; Male; Motivation; Nucleus Accumbens; Personality Inventory; Phobic Disorders; Positron-Emission Tomography; Psychometrics; Raclopride; Receptors, Dopamine D2; Reward; Tomography, Emission-Computed, Single-Photon; Young Adult | 2009 |
Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nucleus Accumbens; Prosencephalon; Rats; Rats, Sprague-Dawley; Reward | 2009 |
Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Recurrence; Reward; Self Administration; Substance Withdrawal Syndrome | 2009 |
Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward.
Topics: Animals; Cells, Cultured; Cocaine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; NF-kappa B; Nucleus Accumbens; PC12 Cells; Rats; Reward; Signal Transduction | 2009 |
Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice.
Topics: Analysis of Variance; Animals; Antimanic Agents; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cues; Dopamine Uptake Inhibitors; Eating; Food Preferences; Lithium Chloride; Male; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-fos; Reward; Saccharin; Self Administration; Sweetening Agents | 2009 |
Gestational methylmercury exposure selectively increases the sensitivity of operant behavior to cocaine.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cocaine; Conditioning, Operant; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Male; Methylmercury Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward | 2009 |
The melanin-concentrating hormone system modulates cocaine reward.
Topics: Animals; Behavior; Cocaine; Cues; Dopamine; Hypothalamic Hormones; Male; Melanins; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleus Accumbens; Pituitary Hormones; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Somatostatin; Reward; Self Administration; Stress, Physiological | 2009 |
Chronic treatment with monoamine oxidase-B inhibitors decreases cocaine reward in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Feeding Behavior; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Reinforcement Schedule; Reward; Serotonin; Time Factors | 2009 |
Balancing risk and reward: a rat model of risky decision making.
Topics: Amphetamine; Analysis of Variance; Animals; Behavior, Animal; Biophysics; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Decision Making; Dopamine Uptake Inhibitors; Electroshock; Male; Models, Animal; Probability Learning; Rats; Rats, Long-Evans; Reaction Time; Reward; Risk-Taking; Satiety Response; Task Performance and Analysis; Time Factors | 2009 |
The encoding of cocaine vs. natural rewards in the striatum of nonhuman primates: categories with different activations.
Topics: Action Potentials; Animals; Basal Ganglia; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Macaca mulatta; Male; Neural Pathways; Neurons; Neuropsychological Tests; Photic Stimulation; Reinforcement, Psychology; Reward; Signal Processing, Computer-Assisted | 2009 |
Effects of self-administered cocaine in adolescent and adult male rats on orbitofrontal cortex-related neurocognitive functioning.
Topics: Age Factors; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cognition; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Learning; Male; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration | 2009 |
Cocaine and automaintained responding in pigeons: rate-reducing effects and tolerance thereto with different durations of food delivery.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Female; Food; Reward | 2009 |
N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intravenous; Male; Microdialysis; Neuroprotective Agents; Organophosphorus Compounds; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration | 2010 |
Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Plasma Membrane Transport Proteins; Environment; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Social Environment; Tyrosine 3-Monooxygenase | 2009 |
D-serine facilitates the effects of extinction to reduce cocaine-primed reinstatement of drug-seeking behavior.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Association Learning; Behavior, Addictive; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Drug Interactions; Excitatory Amino Acid Agonists; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration; Serine | 2009 |
The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward.
Topics: Animals; Benztropine; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression; Male; Mice; Motor Activity; Nomifensine; Proto-Oncogene Proteins c-fos; Reward; Space Perception; Stereotyped Behavior | 2009 |
A neurocomputational model for cocaine addiction.
Topics: Algorithms; Animals; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Computer Simulation; Decision Making; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Humans; Impulsive Behavior; Learning; Reinforcement, Psychology; Reward | 2009 |
Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB.
Topics: Animals; Cocaine; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Mice; Mice, Knockout; Nucleus Accumbens; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Reward; Septum of Brain; Space Perception; Stress, Psychological; Swimming; Time Factors | 2009 |
Diazepam and cocaine potentiate brain stimulation reward in C57BL/6J mice.
Topics: Animals; Cocaine; Conditioning, Operant; Diazepam; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes, Implanted; Hypnotics and Sedatives; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Reward; Self Stimulation; Staining and Labeling | 2010 |
Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Extracellular Space; Male; Microdialysis; Motor Activity; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reward | 2009 |
Evaluating dopamine reward pathway in ADHD: clinical implications.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Brain; Brain Mapping; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Mesencephalon; Positron-Emission Tomography; Raclopride; Receptors, Dopamine D2; Reward; Synaptic Transmission | 2009 |
Acute sleep deprivation increases the rate and efficiency of cocaine self-administration, but not the perceived value of cocaine reward in rats.
Topics: Animals; Behavior, Addictive; Cocaine; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration; Sleep Deprivation; Time Factors | 2009 |
A dopamine transport inhibitor with markedly low abuse liability suppresses cocaine self-administration in the rat.
Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Sucrose | 2009 |
Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction.
Topics: Animals; Behavior, Addictive; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Humans; Infusions, Intravenous; Long-Term Potentiation; Long-Term Synaptic Depression; Microinjections; Neural Pathways; Reinforcement, Psychology; Reward; Self Stimulation; Substantia Nigra; Ventral Tegmental Area | 2009 |
Footshock stress potentiates cue-induced cocaine-seeking in an animal model of relapse.
Topics: Anesthetics, Local; Animals; Behavior, Addictive; Biophysics; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Electroshock; Extinction, Psychological; Male; Multivariate Analysis; Rats; Rats, Long-Evans; Reward; Secondary Prevention; Self Administration; Stress, Psychological | 2009 |
Brain-derived neurotrophic factor signaling modulates cocaine induction of reward-associated ultrasonic vocalization in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indole Alkaloids; Injections, Intraventricular; Male; Motor Activity; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptor, trkB; Reward; Signal Transduction; Ultrasonics; Vocalization, Animal | 2010 |
Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice.
Topics: Alcohol Drinking; Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Electric Stimulation; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reward; Self Stimulation; Species Specificity | 2010 |
Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference.
Topics: Animals; Central Nervous System Stimulants; Choice Behavior; Cocaine; Conditioning, Psychological; Male; Mice; Mice, Knockout; Motor Activity; Receptors, Kainic Acid; Reward | 2010 |
Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats.
Topics: Administration, Oral; Amino Acids; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutarates; Male; Rats; Receptors, Metabotropic Glutamate; Reward; Self Administration; Stereoisomerism; Sucrose; Sulfhydryl Compounds; Time Factors; Xanthenes | 2010 |
Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Guanidines; Male; Morpholines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement Schedule; Reward; Self Administration | 2010 |
Quetiapine blocks cocaine-induced enhancement of brain stimulation reward.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Biophysics; Cocaine; Conditioning, Operant; Dibenzothiazepines; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Male; Medial Forebrain Bundle; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration | 2010 |
Tolerance and sensitization to the effects of cocaine use in humans: a retrospective study of long-term cocaine users in Philadelphia.
Topics: Adult; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Drug Costs; Drug Tolerance; Euphoria; Female; Humans; Male; Middle Aged; Models, Biological; Models, Psychological; Philadelphia; Poisoning; Retrospective Studies; Reward; Sexual Behavior; Time Factors | 2009 |
The effects of infusions of CART 55-102 into the basolateral amygdala on amphetamine-induced conditioned place preference in rats.
Topics: Amphetamine; Amygdala; Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Nerve Tissue Proteins; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reward | 2010 |
Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice.
Topics: Animals; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Piperidines; Protein Kinase C; Protein Kinase Inhibitors; Reward; Time Factors | 2010 |
The effects of adolescent methylphenidate self-administration on responding for a conditioned reward, amphetamine-induced locomotor activity, and neuronal activation.
Topics: Age Factors; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Early Growth Response Protein 1; Male; Methylphenidate; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; RNA, Messenger; Self Administration | 2010 |
A similar pattern of neuronal Fos activation in 10 brain regions following exposure to reward- or aversion-associated contextual cues in mice.
Topics: Animals; Avoidance Learning; Brain; Cocaine; Conditioning, Classical; Cues; Lithium Chloride; Male; Mice; Mice, Inbred ICR; Neurons; Proto-Oncogene Proteins c-fos; Reward | 2010 |
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dendritic Spines; Down-Regulation; Enzyme Repression; Gene Expression Profiling; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Histones; Lysine; Male; Methylation; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-fos; Reward; Self Administration; Transcription, Genetic | 2010 |
Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Mice, Inbred ICR; Reward; Theophylline | 2010 |
Effect of cocaine sensitization prior to pregnancy on maternal care and aggression in the rat.
Topics: Aggression; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Darkness; Female; Lactation; Light; Male; Maternal Behavior; Pregnancy; Rats; Rats, Long-Evans; Reward; Time Factors | 2010 |
Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.
Topics: Adult; Animals; Azides; Benzodiazepines; Binding Sites; Case-Control Studies; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Female; Humans; Learning; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Nucleus Accumbens; Point Mutation; Polymorphism, Single Nucleotide; Receptors, GABA-A; Reward; Young Adult | 2010 |
Competition between novelty and cocaine conditioned reward is sensitive to drug dose and retention interval.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Rats; Rats, Sprague-Dawley; Retention, Psychology; Reward; Time Factors | 2010 |
Intra-accumbens rimonabant is rewarding but induces aversion to cocaine in cocaine-treated rats, as does in vivo accumbal cannabinoid CB1 receptor silencing: critical role for glutamate receptors.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Drug Inverse Agonism; Gene Silencing; Lentivirus; Ligands; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Glutamate; Reward; Rimonabant | 2010 |
Sugar overconsumption during adolescence selectively alters motivation and reward function in adult rats.
Topics: Age Factors; Anesthetics, Local; Animals; Body Weight; Cocaine; Dietary Carbohydrates; Feeding Behavior; Food Preferences; Mice; Motivation; Polysaccharides; Rats; Rats, Wistar; Reward; Saccharin; Self Administration; Sucrose; Sweetening Agents | 2010 |
The concept of pharmacologic cocaine interception as a treatment for drug abuse.
Topics: Animals; Antibodies; Biological Transport; Brain; Cocaine; Drug Therapy, Combination; Humans; Hydrolases; Hydrolysis; Mice; Rats; Reward; Substance-Related Disorders | 2010 |
Learning that a cocaine reward is smaller than expected: A test of Redish's computational model of addiction.
Topics: Animals; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Computer Simulation; Learning; Male; Models, Psychological; Neuropsychological Tests; Rats; Rats, Long-Evans; Reward | 2010 |
The high affinity dopamine uptake inhibitor, JHW 007, blocks cocaine-induced reward, locomotor stimulation and sensitization.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benztropine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Male; Maze Learning; Mice; Motor Activity; Reward | 2010 |
Hippocampal theta rhythm and drug-related reward-seeking behavior: an analysis of cocaine-induced conditioned place preference in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Exploratory Behavior; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Reward; Theta Rhythm | 2010 |
Effect of acute and repeated cocaine exposure on response matching capabilities of Sprague-Dawley rats responding for sucrose on concurrent schedules of reinforcement.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Reinforcement Schedule; Reward; Sucrose | 2010 |
Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Exploratory Behavior; Male; Mental Recall; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reward; Stress, Psychological; Swimming | 2010 |
Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors.
Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Cocaine; Dopamine; Evoked Potentials; Male; Morphine; Neurons; Nicotine; Nucleus Accumbens; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reward; Ventral Tegmental Area | 2010 |
Persistent increases in cocaine-seeking behavior after acute exposure to cold swim stress.
Topics: Animals; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Environment; Extinction, Psychological; Male; Motivation; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration; Stress, Physiological | 2010 |
Reference place conditioning procedure with cocaine: increased sensitivity for measuring associatively motivated choice behavior in rats.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Motivation; Rats; Rats, Sprague-Dawley; Reference Standards; Reward | 2010 |
Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
Topics: Animals; Behavior, Animal; beta-Cyclodextrins; Brain-Derived Neurotrophic Factor; Cholesterol; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dronabinol; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agents; Haloperidol; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward | 2010 |
The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Biphenyl Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Cocaine; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Extinction, Psychological; Feeding Behavior; Glutamic Acid; Humans; Indans; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Reward; Self Administration; Time Factors | 2010 |
Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference.
Topics: Amphetamine; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine; Drug Delivery Systems; Male; Mice; Motor Activity; Nucleus Accumbens; Receptors, Ghrelin; Reward; Signal Transduction | 2010 |
Role of serotonin 5-HT2A and 5-HT2C receptors on brain stimulation reward and the reward-facilitating effect of cocaine.
Topics: Animals; Brain; Cocaine; Dopamine; Electric Stimulation; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Reward; Serotonin Antagonists; Serotonin Receptor Agonists | 2011 |
Neuroscience: MicroRNA knocks down cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cyclic AMP Response Element-Binding Protein; MAP Kinase Kinase Kinases; MicroRNAs; Neostriatum; Proto-Oncogene Proteins c-raf; Rats; Repressor Proteins; Reward | 2010 |
Striatal microRNA controls cocaine intake through CREB signalling.
Topics: Adenylyl Cyclases; Animals; Cocaine; Cocaine-Related Disorders; Cyclic AMP Response Element-Binding Protein; Male; MAP Kinase Kinase Kinases; MicroRNAs; Neostriatum; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Reward; Signal Transduction; Transcription Factors; Up-Regulation | 2010 |
Chronic forced exercise during adolescence decreases cocaine conditioned place preference in Lewis rats.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Female; Male; Physical Conditioning, Animal; Rats; Rats, Inbred Lew; Reward | 2010 |
Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior.
Topics: Action Potentials; Adaptation, Physiological; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Central Nervous System Stimulants; Cholera Toxin; Cocaine; Conditioning, Operant; Corpus Striatum; Dependovirus; Dopamine Uptake Inhibitors; Doxycycline; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Methamphetamine; Mice; Mice, Transgenic; Neural Pathways; Neurons; Neurotoxins; Proto-Oncogene Proteins c-fos; Recombinant Fusion Proteins; Reward; RNA, Messenger; Substantia Nigra; Synaptic Transmission; Tetanus Toxin; Transfection; Vesicle-Associated Membrane Protein 2 | 2010 |
Enhancing the salience of dullness: behavioral and pharmacological strategies to facilitate extinction of drug-cue associations in adolescent rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Uptake Inhibitors; Age Factors; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Cocaine; Conditioning, Psychological; Cues; Dopamine; Extinction, Psychological; Extracellular Space; Male; Memory; Microinjections; Narcotics; Norepinephrine; Prefrontal Cortex; Propylamines; Rats; Receptors, Dopamine D1; Reward | 2010 |
Muscarinic type 2 receptors in the lateral dorsal tegmental area modulate cocaine and food seeking behavior in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Microinjections; Motor Activity; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Reinforcement Schedule; Reward; Self Administration; Tegmentum Mesencephali | 2010 |
Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats.
Topics: Analgesics, Opioid; Animals; Benzimidazoles; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Combinations; Imidazoles; Injections, Intraperitoneal; Male; Morphine Derivatives; Motivation; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reward; Spiro Compounds | 2010 |
The effect of denervation of the locus coeruleus projections with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) on cocaine-induced locomotion and place preference in rats.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Operant; Denervation; Dopamine; Dopamine Uptake Inhibitors; Frontal Lobe; Hippocampus; Locus Coeruleus; Male; Motor Activity; Neural Pathways; Norepinephrine; Rats; Rats, Wistar; Reward | 2011 |
D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Cycloserine; Environment; Extinction, Psychological; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors | 2010 |
Influence of new deltorphin analogues on reinstatement of cocaine-induced conditioned place preference in rats.
Topics: Animals; Behavior, Addictive; Behavioral Research; Cocaine; Conditioning, Psychological; Infusions, Intraventricular; Maze Learning; Motor Activity; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, delta; Reward | 2010 |
Estradiol lowers intracranial self-stimulation thresholds and enhances cocaine facilitation of intracranial self-stimulation in rats.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Down-Regulation; Estradiol; Female; Male; Ovariectomy; Rats; Rats, Wistar; Reward; Self Stimulation; Sex Characteristics | 2010 |
Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Humans; Male; Mesencephalon; Motivation; Nucleus Accumbens; Personality Inventory; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward | 2011 |
Sub-region specific contribution of the ventral hippocampus to drug context-induced reinstatement of cocaine-seeking behavior in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Reward | 2010 |
Effects of cannabinoid CB₁ receptor antagonist rimonabant on acquisition and reinstatement of psychostimulant reward memory in mice.
Topics: Animals; Cannabinoid Receptor Antagonists; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Methamphetamine; Mice; Mice, Inbred Strains; Piperidines; Pyrazoles; Reward; Rimonabant | 2011 |
Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Channelrhodopsins; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Light; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Motor Activity; Neurons; Nucleus Accumbens; Receptor, trkB; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; RNA, Messenger; Signal Transduction | 2010 |
Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine; Infusions, Parenteral; Injections, Intravenous; Intracellular Signaling Peptides and Proteins; Male; Microdialysis; Motivation; Neuropeptides; Orexins; Potentiometry; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Signal Transduction; Time Factors; Ventral Tegmental Area | 2011 |
Prolonged attenuation of the reinforcing strength of cocaine by chronic d-amphetamine in rhesus monkeys.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dextroamphetamine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Macaca mulatta; Male; Reinforcement, Psychology; Reward; Self Administration; Time Factors | 2011 |
Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats.
Topics: Animals; Butyrylcholinesterase; Cocaine; Female; Humans; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration | 2011 |
Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Male; Morphine; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Thiazoles | 2011 |
Inhibition of neuronal nitric oxide synthase prevents alterations in medial prefrontal cortex excitability induced by repeated cocaine administration.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Enzyme Inhibitors; Indazoles; Male; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome | 2011 |
Protracted cocaine withdrawal produces circadian rhythmic alterations of phosphorylated GSK-3β in reward-related brain areas in rats.
Topics: Analysis of Variance; Animals; Blotting, Western; Circadian Rhythm; Cocaine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Motor Activity; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome; Suprachiasmatic Nucleus; Ventral Tegmental Area | 2011 |
CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine.
Topics: Amygdala; Animals; Behavior, Addictive; Brain; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Extinction, Psychological; Female; Gene Expression Profiling; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Targeted Therapy; Reward; Transcription Factors; Transcriptome | 2011 |
At what stage of neural processing does cocaine act to boost pursuit of rewards?
Topics: Animals; Cocaine; Conditioning, Operant; Electric Stimulation; Hypothalamus; Male; Neurons; Rats; Rats, Long-Evans; Reward; Synaptic Transmission; Time Factors; Vasoconstrictor Agents | 2010 |
Cholinergic interneurons control local circuit activity and cocaine conditioning.
Topics: Acetylcholine; Action Potentials; Animals; Behavior, Animal; Choline O-Acetyltransferase; Cocaine; Conditioning, Psychological; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Transgenic; Motor Activity; Neurons; Nucleus Accumbens; Reward; Synaptic Potentials | 2010 |
Activation of dopamine D3 receptors inhibits reward-related learning induced by cocaine.
Topics: Animals; Blotting, Western; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Enzyme Activation; Female; Learning; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Receptors, Dopamine D3; Reward; Signal Transduction | 2011 |
Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Psychological; Galanin; Male; Mice; Mice, 129 Strain; Mice, Congenic; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Morphine; Nicotine; Nucleus Accumbens; Phosphorylation; Reward; Signal Transduction; Synaptic Transmission | 2011 |
The first universal opioid ligand, (2S)-2-[(5R,6R,7R,14S)-N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol (BU08028): characterization of the in vitro profile and in vivo behavioral effects in mouse mode
Topics: Acute Disease; Analgesics, Opioid; Animals; Buprenorphine; CHO Cells; Cocaine; Cricetinae; Cricetulus; Disease Models, Animal; Humans; Ligands; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Protein Binding; Receptors, Opioid; Reward | 2011 |
Down-regulated striatal gene expression for synaptic plasticity-associated proteins in addiction and relapse vulnerable animals.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Classical; Corpus Striatum; Dopamine Uptake Inhibitors; Down-Regulation; Extinction, Psychological; Gene Expression; Male; Molecular Targeted Therapy; Motivation; Neuronal Plasticity; Proteins; Rats; Rats, Sprague-Dawley; Reward; Secondary Prevention; Self Administration; Substance-Related Disorders; Synapses; TOR Serine-Threonine Kinases | 2011 |
Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nicotine; Nucleus Accumbens; Reward; Sex Characteristics; Species Specificity | 2011 |
Orexin-1 receptor antagonist SB-334867 reduces the acquisition and expression of cocaine-conditioned reinforcement and the expression of amphetamine-conditioned reward.
Topics: Animals; Behavior, Animal; Benzoxazoles; Cocaine; Conditioning, Operant; Cues; Dextroamphetamine; Discrimination Learning; Male; Naphthyridines; Orexin Receptors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement Schedule; Reward; Self Administration; Urea | 2011 |
Opioid facilitation of rewarding electrical brain stimulation is suppressed in rats with neuropathic pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Heroin; Hyperalgesia; Ligation; Male; Morphine; Neuralgia; Pain Measurement; Pressure; Rats; Rats, Inbred F344; Reward; Self Stimulation; Spinal Nerves; Ventral Tegmental Area | 2011 |
Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens.
Topics: Analysis of Variance; Animals; Base Sequence; Blotting, Western; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; DNA Primers; Gene Regulatory Networks; Genomic Instability; Heterochromatin; Histones; Immunohistochemistry; Long Interspersed Nucleotide Elements; Lysine; Methylation; Mice; Models, Statistical; Molecular Sequence Data; Nucleus Accumbens; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Reward; Sequence Analysis, DNA | 2011 |
The GABA-B positive modulator GS39783 decreases psychostimulant conditioned-reinforcement and conditioned-reward.
Topics: Allosteric Regulation; Amphetamine; Animals; Association Learning; Baclofen; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Cyclopentanes; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Motivation; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, GABA-B; Reinforcement Schedule; Reward; Self Administration | 2011 |
Dorsal as well as ventral striatal lesions affect levels of intravenous cocaine and morphine self-administration in rats.
Topics: Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Morphine; Narcotics; Neostriatum; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance-Related Disorders | 2011 |
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Oligopeptides; Organophosphonates; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Time Factors; Valine | 2011 |
Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Cues; Dopamine; Dopamine Uptake Inhibitors; Drive; Electrochemistry; Emotions; Male; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2011 |
Effects of lidocaine-induced inactivation of the bed nucleus of the stria terminalis, the central or the basolateral nucleus of the amygdala on the opponent-process actions of self-administered cocaine in rats.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Lidocaine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Septal Nuclei | 2011 |
YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.
Topics: Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluorenes; Guanosine 5'-O-(3-Thiotriphosphate); Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nitriles; Piperazines; Quinpirole; Radioligand Assay; Random Allocation; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Self Administration; Sucrose; Tetrahydroisoquinolines | 2012 |
Changes in the magnitude of drug-unconditioned stimulus during conditioning modulate cocaine-induced place preference in mice.
Topics: Animals; Association Learning; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Reinforcement Schedule; Reward; Sodium Chloride | 2012 |
Beta-lactam antibiotic decreases acquisition of and motivation to respond for cocaine, but not sweet food, in C57Bl/6 mice.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 2; Food; Male; Mice; Mice, Inbred C57BL; Motivation; Reinforcement Schedule; Reinforcement, Psychology; Reward; Self Administration | 2011 |
Withdrawal from chronic cocaine administration induces deficits in brain reward function in C57BL/6J mice.
Topics: Animals; Brain; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Infusion Pumps, Implantable; Male; Mice; Mice, Inbred C57BL; Microinjections; Motor Activity; Reward; Self Stimulation; Substance Withdrawal Syndrome | 2011 |
Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues.
Topics: Animals; Azepines; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Dietary Sucrose; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Feeding Behavior; Impulsive Behavior; Indoles; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reward; Self Administration; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Cocaine enhances resistance to extinction of responding for brain-stimulation reward in adult prenatally stressed rats.
Topics: Analysis of Variance; Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Extinction, Psychological; Female; Hypothalamo-Hypophyseal System; Male; Medial Forebrain Bundle; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reward; Stress, Psychological | 2011 |
Glycogen synthase kinase 3β in the basolateral amygdala is critical for the reconsolidation of cocaine reward memory.
Topics: Adjuvants, Immunologic; Amygdala; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Lithium Chloride; Male; Maleimides; Memory; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2011 |
Enhanced cocaine-conditioned place preference and associated brain regional levels of BDNF, p-ERK1/2 and p-Ser845-GluA1 in food-restricted rats.
Topics: Analysis of Variance; Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; Enzyme-Linked Immunosorbent Assay; Food Deprivation; Male; Mitogen-Activated Protein Kinase 3; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reward; Serine; Signal Transduction | 2011 |
Work aversion and associated changes in dopamine and serotonin transporter after methamphetamine exposure in rats.
Topics: Animals; Cocaine; Corpus Striatum; Decision Making; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Frontal Lobe; Male; Maze Learning; Methamphetamine; Physical Exertion; Radioligand Assay; Rats; Rats, Long-Evans; Reward; Serotonin Plasma Membrane Transport Proteins | 2012 |
Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Bicuculline; Biotin; Cerebral Cortex; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Green Fluorescent Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Patch-Clamp Techniques; Reward; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase | 2011 |
Escalated or suppressed cocaine reward, tegmental BDNF, and accumbal dopamine caused by episodic versus continuous social stress in rats.
Topics: Analysis of Variance; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Food Handling; Gene Expression Regulation; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Oncogene Proteins v-fos; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Stress, Psychological; Sucrose; Time Factors; Ventral Tegmental Area | 2011 |
Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors.
Topics: Analysis of Variance; Animals; Autoradiography; Baclofen; Choice Behavior; Cocaine; Conditioning, Operant; Dihydroxyphenylalanine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Exploratory Behavior; Food; GABA-B Receptor Agonists; Hydrazines; Hyperkinesis; In Vitro Techniques; Maze Learning; Membrane Potentials; Mesencephalon; Mice; Mice, Knockout; Motivation; Motor Activity; Neurons; Quinpirole; Receptors, Dopamine D2; Reinforcement Schedule; Reward; Sulpiride | 2011 |
Subchronic steroid administration induces long lasting changes in neurochemical and behavioral response to cocaine in rats.
Topics: Anabolic Agents; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Male; Microdialysis; Motor Activity; Nandrolone; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Serotonin; Stereotyped Behavior | 2011 |
Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Diterpenes, Clerodane; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Male; Naltrexone; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Signal Transduction; Time Factors | 2011 |
Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area.
Topics: Action Potentials; Animals; Behavior, Animal; Brain Mapping; CA3 Region, Hippocampal; Cocaine; Dopamine; Drug-Seeking Behavior; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Models, Neurological; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Septal Nuclei; Theta Rhythm; Ventral Tegmental Area | 2011 |
Addictive potential of modafinil and cross-sensitization with cocaine: a pre-clinical study.
Topics: Animals; Benzhydryl Compounds; Brain; Central Nervous System Sensitization; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Mice; Modafinil; Motivation; Motor Activity; Neuronal Plasticity; Reward; Social Environment; Substance-Related Disorders | 2011 |
Extracellular signal-regulated kinase signaling in the ventral tegmental area mediates cocaine-induced synaptic plasticity and rewarding effects.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzoxazines; Biophysics; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; GABA Antagonists; In Vitro Techniques; Male; Morpholines; Naphthalenes; Neuronal Plasticity; Patch-Clamp Techniques; Picrotoxin; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reward; Signal Transduction; Synapses; Ventral Tegmental Area | 2011 |
A cocaine cue is more preferred and evokes more frequency-modulated 50-kHz ultrasonic vocalizations in rats prone to attribute incentive salience to a food cue.
Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Feeding Behavior; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Ultrasonics; Vocalization, Animal | 2012 |
The missing variable: ultrasonic vocalizations reveal hidden sensitization and tolerance-like effects during long-term cocaine administration.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Drug Tolerance; Extinction, Psychological; Locomotion; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Ultrasonics; Vocalization, Animal | 2012 |
Enhanced sucrose and cocaine self-administration and cue-induced drug seeking after loss of VGLUT2 in midbrain dopamine neurons in mice.
Topics: Analysis of Variance; Animals; Autoradiography; Behavior, Addictive; Behavior, Animal; Cell Death; Cocaine; Conditioning, Operant; Cues; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemical Techniques; Food Preferences; Gene Expression Regulation; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 1; Potassium Chloride; Protein Binding; Proto-Oncogene Proteins c-fos; Receptors, Dopamine; Reinforcement Schedule; Reward; RNA, Messenger; Self Administration; Sucrose; Vesicular Glutamate Transport Protein 2 | 2011 |
Cocaine-induced impulsive choices are accompanied by impaired delay-dependent anticipatory activity in basolateral amygdala.
Topics: Algorithms; Amygdala; Animals; Anticipation, Psychological; Choice Behavior; Cocaine; Conditioning, Operant; Cues; Data Interpretation, Statistical; Electrodes, Implanted; Electrophysiological Phenomena; Impulsive Behavior; Light; Male; Neurons; Rats; Rats, Sprague-Dawley; Reaction Time; Reward | 2012 |
The effect of a novel VMAT2 inhibitor, GZ-793A, on methamphetamine reward in rats.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Food; Lobeline; Male; Methamphetamine; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Vesicular Monoamine Transport Proteins | 2012 |
Sweets, sex, or self-esteem? Comparing the value of self-esteem boosts with other pleasant rewards.
Topics: Analysis of Variance; Candy; Feeding Behavior; Female; Humans; Male; Michigan; Narcissism; Personality; Personality Inventory; Reward; Self Concept; Sex; Social Values; Students; Universities | 2011 |
ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Anesthetics, Local; Animals; Biophysics; Cocaine; Conditioning, Operant; Corpus Striatum; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypothalamic Area, Lateral; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos; Receptors, Opioid, kappa; Reward; Self Stimulation | 2012 |
Alk is a transcriptional target of LMO4 and ERα that promotes cocaine sensitization and reward.
Topics: Adaptor Proteins, Signal Transducing; Anaplastic Lymphoma Kinase; Animals; Animals, Newborn; Cells, Cultured; Cocaine; Estrogen Receptor alpha; Gene Targeting; HEK293 Cells; Humans; LIM Domain Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptor Protein-Tyrosine Kinases; Reward; Transcription, Genetic | 2011 |
Modulatory effects of low-dose MDMA on cocaine-induced locomotor activity and place conditioning in rats.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Hallucinogens; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Serotonin Agents | 2012 |
Intravascular food reward.
Topics: Animals; Behavior, Animal; Blood Glucose; Cocaine; Dopamine; Electrochemistry; Feeding Behavior; Food; Glucose; Jugular Veins; Male; Models, Cardiovascular; Mucous Membrane; Portal Vein; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reward; Time Factors | 2011 |
Seeking-taking chain schedules of cocaine and sucrose self-administration: effects of reward size, reward omission, and α-flupenthixol.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Flupenthixol; Male; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Sucrose | 2012 |
Interaction between the basolateral amygdala and dorsal hippocampus is critical for cocaine memory reconsolidation and subsequent drug context-induced cocaine-seeking behavior in rats.
Topics: Amygdala; Analysis of Variance; Animals; Association Learning; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Environment; Extinction, Psychological; Hippocampus; Male; Memory, Long-Term; Neural Pathways; Rats; Rats, Sprague-Dawley; Reward | 2011 |
Cues paired with either rapid or slower self-administered cocaine injections acquire similar conditioned rewarding properties.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Rats; Rats, Wistar; Reward; Self Administration | 2011 |
Juvenile and adult rats differ in cocaine reward and expression of zif268 in the forebrain.
Topics: Aging; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Gene Expression Regulation; Locomotion; Male; Prosencephalon; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger | 2012 |
NMDA receptor glycine modulatory site in the ventral tegmental area regulates the acquisition, retrieval, and reconsolidation of cocaine reward memory.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Classical; Glycine; Kynurenic Acid; Male; Memory; Microinjections; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Substantia Nigra; Ventral Tegmental Area | 2012 |
Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: alleviation by CRF₁ receptor antagonism.
Topics: Alcoholism; Animals; Cocaine; Cocaine-Related Disorders; Heroin; Heroin Dependence; Hyperalgesia; Male; Pain Perception; Pain Threshold; Physical Stimulation; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reward; Self Administration | 2012 |
Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice.
Topics: Animals; Benzoxazoles; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Male; Mice; Motor Activity; Naphthyridines; Orexin Receptors; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement Schedule; Reward; Self Administration; Urea | 2012 |
Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal.
Topics: Anhedonia; Animals; Brain; Cocaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Self Stimulation; Substance Withdrawal Syndrome; Time Factors | 2012 |
Alteration of c-Fos mRNA in the accessory lobe of crayfish is associated with a conditioned-cocaine induced reward.
Topics: Animals; Astacoidea; Behavior, Animal; Brain; Cocaine; Conditioning, Psychological; Male; Motor Activity; Proto-Oncogene Proteins c-fos; Reward | 2012 |
The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice.
Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Male; Mice; Motor Activity; Nucleus Accumbens; Receptors, AMPA; Reward; Ventral Tegmental Area | 2012 |
CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain.
Topics: 14-3-3 Proteins; Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Brain Chemistry; Cocaine; Conditioning, Operant; DNA, Complementary; Gene Expression; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Motor Activity; Piperazines; Prealbumin; Real-Time Polymerase Chain Reaction; Receptors, sigma; Reinforcement Schedule; Reward; RNA; RNA, Long Noncoding; RNA, Untranslated; Seizures; Sulfur Compounds | 2012 |
Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction.
Topics: Active Transport, Cell Nucleus; Animals; Cocaine; Cyclic AMP; Dopamine Uptake Inhibitors; Histone Deacetylases; Humans; Male; Reward | 2012 |
Histone deacetylase 5 limits cocaine reward through cAMP-induced nuclear import.
Topics: Active Transport, Cell Nucleus; Analysis of Variance; Animals; Cells, Cultured; Cocaine; Conditioning, Operant; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase 5; Dopamine Uptake Inhibitors; Embryo, Mammalian; Food Preferences; Histone Deacetylases; Humans; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Models, Biological; Mutation; Neurons; Protein Phosphatase 2; Rats; Reward; Sucrose; Sweetening Agents; Time Factors; Transfection | 2012 |
Juvenile exposure to methylphenidate reduces cocaine reward and alters netrin-1 receptor expression in adulthood.
Topics: Animals; Animals, Newborn; Cocaine; Conditioning, Operant; Cues; DCC Receptor; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Receptors, Cell Surface; Reward; Tumor Suppressor Proteins; Ventral Tegmental Area | 2012 |
Operant model of frustrated expected reward in mice.
Topics: Aggression; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Eating; Extinction, Psychological; Frustration; Male; Mice; Mice, Inbred C57BL; Reinforcement Schedule; Reward; Self Administration | 2012 |
Characterization of a semi-rapid method for assessing delay discounting in rodents.
Topics: Animals; Choice Behavior; Cocaine; Impulsive Behavior; Male; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2012 |
Transfer of neuroplasticity from nucleus accumbens core to shell is required for cocaine reward.
Topics: Animals; Anisomycin; Cocaine; Conditioning, Operant; Dendritic Spines; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microscopy, Confocal; Neuronal Plasticity; Nucleus Accumbens; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reward | 2012 |
Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation.
Topics: Analysis of Variance; Animals; Benzazepines; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Impulsive Behavior; Male; Methylphenidate; Predictive Value of Tests; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Risk Factors; Secondary Prevention; Self Administration; Statistics as Topic; Time Factors | 2012 |
Cocaine self-administration is not dependent upon mesocortical α1 noradrenergic signaling.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine; Dopamine Antagonists; Male; Norepinephrine; Prazosin; Prefrontal Cortex; Rats; Reinforcement, Psychology; Reward; Self Administration; Ventral Tegmental Area | 2012 |
Adolescent exposure to methylphenidate has no effect on the aversive properties of cocaine in adulthood.
Topics: Animals; Avoidance Learning; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Male; Methylphenidate; Models, Animal; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Taste | 2012 |
Ethanol exposure during either adolescence or adulthood alters the rewarding effects of cocaine in adult rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Reward | 2012 |
The dual orexin receptor antagonist almorexant, alone and in combination with morphine, cocaine and amphetamine, on conditioned place preference and locomotor sensitization in the rat.
Topics: Acetamides; Amphetamine; Anesthetics; Animals; Cocaine; Conditioning, Operant; Dopamine Agents; Drug Interactions; Dual Oxidases; Flavoproteins; Isoquinolines; Locomotion; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward | 2013 |
Neural correlates of the formation and retention of cocaine-induced stimulus-reward associations.
Topics: Animals; Cerebral Cortex; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Drug-Seeking Behavior; Macaca mulatta; Magnetic Resonance Imaging; Male; Reward | 2012 |
Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward.
Topics: Animals; Behavior, Animal; Benztropine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Exploratory Behavior; Histamine H1 Antagonists; Illicit Drugs; Kinetics; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Piperidines; Psychomotor Agitation; Reward; Spatial Behavior | 2012 |
Circadian discrimination of reward: evidence for simultaneous yet separable food- and drug-entrained rhythms in the rat.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Biological Clocks; Body Temperature Regulation; Caloric Restriction; Central Nervous System Stimulants; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Feeding Behavior; Male; Motor Activity; Photoperiod; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome; Suprachiasmatic Nucleus; Time Factors | 2012 |
High novelty-seeking predicts greater sensitivity to the conditioned rewarding effects of cocaine.
Topics: Animals; Cocaine; Conditioning, Psychological; Exploratory Behavior; Female; Male; Mice; Predictive Value of Tests; Reaction Time; Reward | 2012 |
Role of nicotinic acetylcholine receptors in the effects of cocaine-paired contextual stimuli on impulsive decision making in rats.
Topics: Animals; Behavior, Animal; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Decision Making; Impulsive Behavior; Male; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Reinforcement Schedule; Reward | 2012 |
Shift of circadian feeding pattern by high-fat diets is coincident with reward deficits in obese mice.
Topics: Adipose Tissue; Animals; Body Weight; Circadian Rhythm; Cocaine; Diet, High-Fat; Feeding Behavior; Leptin; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Size; Reward | 2012 |
AMPAR-independent effect of striatal αCaMKII promotes the sensitization of cocaine reward.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Conditioning, Psychological; Corpus Striatum; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Organ Culture Techniques; Receptors, AMPA; Reward; Synapses; Up-Regulation | 2012 |
The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice.
Topics: Animals; Behavior, Animal; beta-Endorphin; Cocaine; Conditioning, Operant; Male; Mice; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Reward | 2012 |
Cocaine-induced c-Fos expression in rats selectively bred for high or low saccharin intake and in rats selected for high or low impulsivity.
Topics: Animals; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Gene Expression Regulation; Impulsive Behavior; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reward; Saccharin; Self Administration | 2012 |
Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine-independent processes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Animal; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Neuropeptides; Neurotransmitter Agents; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Orexin Receptors; Orexins; Patch-Clamp Techniques; Reboxetine; Receptors, Adrenergic, alpha-2; Receptors, Corticotropin-Releasing Hormone; Receptors, Neuropeptide; Reward; Septal Nuclei; Synaptic Transmission; Yohimbine | 2012 |
Bilateral lesions of the thalamic trigeminal orosensory area dissociate natural from drug reward in contrast paradigms.
Topics: Analysis of Variance; Animals; Antimanic Agents; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Conditioning, Operant; Dopamine Uptake Inhibitors; Eating; Excitatory Amino Acid Agonists; Food Preferences; Ibotenic Acid; Lithium Chloride; Male; Morphine; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Saccharin; Taste; Thalamus | 2012 |
Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Male; Medial Forebrain Bundle; Methamphetamine; Mice; Mice, Inbred C57BL; Reward; Self Stimulation; Time Factors | 2012 |
AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors.
Topics: Agouti-Related Protein; Animals; Behavior, Animal; Cocaine; Dopamine; Dopaminergic Neurons; Female; Gene Knockdown Techniques; Long-Term Potentiation; Mice; Mice, Transgenic; Neuronal Plasticity; Neurons; Reward | 2012 |
Differential alteration of the effects of MDMA (ecstasy) on locomotor activity and cocaine conditioned place preference in male adolescent rats by social and environmental enrichment.
Topics: Age Factors; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Hallucinogens; Housing, Animal; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Reward; Social Environment; Social Isolation | 2012 |
Differential roles of GABA(A) receptor subtypes in benzodiazepine-induced enhancement of brain-stimulation reward.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzodiazepines; Brain; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agents; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Protein Subunits; Receptors, GABA-A; Reinforcement Schedule; Reward; Self Stimulation | 2012 |
Common influences of non-competitive NMDA receptor antagonists on the consolidation and reconsolidation of cocaine-cue memory.
Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward | 2013 |
Sensitivity to monetary reward is most severely compromised in recently abstaining cocaine addicted individuals: a cross-sectional ERP study.
Topics: Adult; Brain; Case-Control Studies; Cocaine; Cocaine-Related Disorders; Cross-Sectional Studies; Dopamine Uptake Inhibitors; Electroencephalography; Event-Related Potentials, P300; Female; Humans; Male; Middle Aged; Motivation; Reward | 2012 |
Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Cannabidiol; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes, Implanted; Male; Medial Forebrain Bundle; Microinjections; Morphine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reward; Self Stimulation; Sensory Thresholds; Serotonin Antagonists | 2013 |
Role of dopamine tone in the pursuit of brain stimulation reward.
Topics: Analysis of Variance; Animals; Brain; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Male; Microdialysis; Models, Biological; Piperazines; Rats; Rats, Long-Evans; Reward; Self Stimulation; Time Factors | 2012 |
Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the H₂O₂ scavenger alpha lipoic acid.
Topics: Acetaldehyde; Animals; Antioxidants; Brain; Cocaine; Conditioning, Classical; Ethanol; Hydrogen Peroxide; Mice; Morphine; Reward; Thioctic Acid | 2013 |
Cocaine-induced rewarding properties, behavioural sensitization and alteration in social behaviours in group-housed and postpuberty isolated female mandarin voles.
Topics: Animals; Anxiety; Arvicolinae; Behavior, Animal; Cocaine; Conditioning, Psychological; Female; Motor Activity; Reward; Sexual Maturation; Social Behavior; Social Environment; Social Isolation | 2012 |
Assessing learned associations between conditioned cocaine reward and environmental stimuli in the Wistar Kyoto rat.
Topics: Animals; Anxiety Disorders; Association Learning; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Reward | 2012 |
Inhibitory effects of SA4503 on the rewarding effects of abused drugs.
Topics: Animals; Cocaine; Conditioning, Operant; Conditioning, Psychological; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibition, Psychological; Male; Methamphetamine; Morphine; Narcotics; Nootropic Agents; Pentazocine; Piperazines; Psychomotor Performance; Rats, Inbred F344; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2014 |
Effects of the anticonvulsant lacosamide compared to valproate and lamotrigine on cocaine-enhanced reward in rats.
Topics: Acetamides; Animals; Anticonvulsants; Cocaine; Lacosamide; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Stimulation; Treatment Outcome; Triazines; Valproic Acid | 2012 |
Characterization of Highper, an ENU-induced mouse mutant with abnormal psychostimulant and stress responses.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Corticosterone; Ethanol; Ethylnitrosourea; Female; Hypothalamo-Hypophyseal System; Male; Methylphenidate; Mice; Mice, Mutant Strains; Motor Activity; Mutagenesis; Pituitary-Adrenal System; Restraint, Physical; Reward; Self Administration; Species Specificity; Stress, Physiological | 2013 |
Interactions between modafinil and cocaine during the induction of conditioned place preference and locomotor sensitization in mice: implications for addiction.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Sensitization; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Modafinil; Multivariate Analysis; Reward; Sensitivity and Specificity; Time Factors | 2012 |
Acetylcholine, drug reward and substance use disorder treatment: intra- and interindividual striatal and accumbal neuron ensemble heterogeneity may explain apparent discrepant findings.
Topics: Acetylcholine; Animals; Basal Ganglia; Cocaine; Conditioning, Psychological; Early Growth Response Protein 1; Male; Neurons; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2012 |
Cocaine place conditioning increases pro-opiomelanocortin gene expression in rat hypothalamus.
Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression; Hypothalamus; Male; Pituitary Gland; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger | 2012 |
Cocaine produces conditioned place aversion in mice with a cocaine-insensitive dopamine transporter.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Plasma Membrane Transport Proteins; Inbreeding; Mice; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Reward | 2013 |
A classically conditioned cocaine cue acquires greater control over motivated behavior in rats prone to attribute incentive salience to a food cue.
Topics: Animals; Behavior; Behavior, Addictive; Cocaine; Conditioning, Classical; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Food; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward | 2013 |
Pathway-specific dopaminergic deficits in a mouse model of Angelman syndrome.
Topics: Angelman Syndrome; Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Electric Stimulation; Female; Indoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Raclopride; Receptors, Dopamine D1; Reward; Self Stimulation; Substantia Nigra; Synaptic Transmission; Ubiquitin-Protein Ligases; Ventral Tegmental Area | 2012 |
Oleoylethanolamide dose-dependently attenuates cocaine-induced behaviours through a PPARα receptor-independent mechanism.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Endocannabinoids; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Oleic Acids; PPAR alpha; Reinforcement, Psychology; Reward | 2013 |
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste | 2013 |
Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake.
Topics: Animals; Avoidance Learning; Brain; Cocaine; Corpus Striatum; Dopamine; Dynorphins; G-Protein-Coupled Receptor Kinase 3; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microinjections; Naltrexone; Narcotic Antagonists; Nicotine; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Raphe Nuclei; Receptors, Opioid, kappa; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Stress, Psychological; Substance Withdrawal Syndrome; Synaptosomes | 2012 |
Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice.
Topics: Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cocaine; Female; Haplotypes; Humans; Linkage Disequilibrium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nucleus Accumbens; Phenotype; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2012 |
A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm.
Topics: Animals; Behavior, Animal; Buprenorphine; Cocaine; Conditioning, Psychological; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward | 2014 |
Neural processing of a cocaine-associated odor cue revealed by functional MRI in awake rats.
Topics: Animals; Brain; Brain Mapping; Cocaine; Conditioning, Operant; Cues; Electric Stimulation; Magnetic Resonance Imaging; Male; Odorants; Rats; Rats, Sprague-Dawley; Reward; Sensory Thresholds; Wakefulness | 2013 |
A critical role for protein degradation in the nucleus accumbens core in cocaine reward memory.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Extinction, Psychological; Male; Memory; Nucleus Accumbens; Polyubiquitin; Proteolysis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Reward; Time Factors; Ubiquitin | 2013 |
Extended heroin access increases heroin choices over a potent nondrug alternative.
Topics: Animals; Behavior, Addictive; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Heroin; Male; Narcotics; Rats; Reward; Saccharin; Self Administration | 2013 |
Developmentally divergent effects of Rho-kinase inhibition on cocaine- and BDNF-induced behavioral plasticity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Female; Male; Mice; Mice, Biozzi; Mice, Inbred C57BL; Motor Activity; Neuronal Plasticity; Protein Kinase Inhibitors; Reward; rho-Associated Kinases | 2013 |
Effects of time of feeding on psychostimulant reward, conditioned place preference, metabolic hormone levels, and nucleus accumbens biochemical measures in food-restricted rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Dextroamphetamine; Feeding Behavior; Food Deprivation; Ghrelin; Injections, Intraventricular; Insulin; Male; Nucleus Accumbens; Postprandial Period; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation; Time Factors | 2013 |
The craving stops before you feel it: neural correlates of chocolate craving during cue exposure with response prevention.
Topics: Brain; Brain Mapping; Cacao; Candy; Craving; Cues; Eating; Executive Function; Extinction, Psychological; Female; Humans; Hunger; Magnetic Resonance Imaging; Neural Pathways; Reward; Signal Processing, Computer-Assisted; Time Factors; Visual Perception; Young Adult | 2014 |
Dorsolateral caudate nucleus differentiates cocaine from natural reward-associated contextual cues.
Topics: Animals; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Cues; Discrimination Learning; Magnetic Resonance Imaging; Male; Models, Neurological; Models, Psychological; Neuronal Plasticity; Odorants; Rats; Rats, Long-Evans; Reward; Self Administration; Smell; Visual Cortex | 2013 |
Not all stress is equal: CREB is not necessary for restraint stress reinstatement of cocaine-conditioned reward.
Topics: Analysis of Variance; Animals; Brain; Cocaine; Conditioning, Operant; CREB-Binding Protein; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Restraint, Physical; Reward | 2013 |
Candy and the brain: neural response to candy gains and losses.
Topics: Adult; Brain; Candy; Female; Humans; Image Processing, Computer-Assisted; Learning; Magnetic Resonance Imaging; Male; Motivation; Reinforcement, Psychology; Reward; Young Adult | 2013 |
Conditioned contribution of peripheral cocaine actions to cocaine reward and cocaine-seeking.
Topics: Animals; Cocaine; Conditioning, Operant; Conditioning, Psychological; Dopamine; Drug-Seeking Behavior; Extinction, Psychological; Male; Nucleus Accumbens; Rats; Reward; Self Administration | 2013 |
Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bacterial Proteins; Channelrhodopsins; Clozapine; Cocaine; Compulsive Behavior; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Green Fluorescent Proteins; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Nerve Net; Neural Pathways; Neurons; Nucleus Accumbens; Receptors, Dopamine D2; Reward; Self Administration; Synapses; Time Factors | 2013 |
The medial preoptic area modulates cocaine-induced activity in female rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Female; gamma-Aminobutyric Acid; Motor Activity; Neurons; Nucleus Accumbens; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reward | 2013 |
On the persistence of cocaine-induced place preferences and aversions in rats.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Male; Rats; Rats, Sprague-Dawley; Reward; Time Factors | 2013 |
Reduced cocaine-seeking behavior in heterozygous BDNF knockout rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Female; Rats; Rats, Sprague-Dawley; Repetition Priming; Reward | 2013 |
[β-arrestin2 plays a critical role in reward behaviors induced by cocaine].
Topics: Animals; Arrestins; Behavior, Animal; beta-Arrestin 2; beta-Arrestins; Cocaine; Mice; Mice, Knockout; Motor Activity; Reward | 2013 |
Juvenile ethanol exposure increases rewarding properties of cocaine and morphine in adult DBA/2J mice.
Topics: Age Factors; Analgesics; Animals; Animals, Newborn; Brain; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Ethanol; Extracellular Signal-Regulated MAP Kinases; Locomotion; Male; Mice; Mice, Inbred DBA; Morphine; Reward | 2013 |
Prior extended daily access to cocaine elevates the reward threshold in a conditioned place preference test.
Topics: Amygdala; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Immunohistochemistry; Male; Motivation; Nucleus Accumbens; Prefrontal Cortex; Rats, Sprague-Dawley; Reward; Self Administration | 2014 |
Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brain.
Topics: Activating Transcription Factor 3; Animals; Antigens, Differentiation; Brain; Cocaine; Endoplasmic Reticulum Stress; Gene Expression Regulation; Male; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Stress, Psychological | 2013 |
Repeated cocaine exposure facilitates the expression of incentive motivation and induces habitual control in rats.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Cues; Male; Motivation; Rats; Reward; Substance-Related Disorders | 2013 |
The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice.
Topics: Animals; Anisoles; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclohexanols; Dose-Response Relationship, Drug; Female; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Receptor, Cannabinoid, CB2; Reward; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2013 |
Genetic reconstruction of dopamine D1 receptor signaling in the nucleus accumbens facilitates natural and drug reward responses.
Topics: Analysis of Variance; Animals; Benzazepines; Cocaine; Conditioning, Classical; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Reward; Rotarod Performance Test; Signal Transduction | 2013 |
Glycogen synthase kinase-3β in the ventral tegmental area mediates diurnal variations in cocaine-induced conditioned place preference in rats.
Topics: Animals; Circadian Rhythm; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Glycogen Synthase Kinase 3; Indoles; Male; Maleimides; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Reward; Suprachiasmatic Nucleus; Ventral Tegmental Area | 2014 |
The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.
Topics: Adenine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Cocaine; Corpus Striatum; Dopamine; Dopaminergic Neurons; Exploratory Behavior; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Locomotion; Male; Mesencephalon; Methylation; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mixed Function Oxygenases; Oxo-Acid-Lyases; Phenotype; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction | 2013 |
Partial extinction of a conditioned context enhances preference for elements previously associated with cocaine but not with chocolate.
Topics: Analysis of Variance; Animals; Cacao; Cocaine; Conditioning, Operant; Data Interpretation, Statistical; Dopamine Uptake Inhibitors; Extinction, Psychological; Genes, fos; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Inbred DBA; Motor Activity; Neural Pathways; Reward | 2013 |
A choice-based screening method for compulsive drug users in rats.
Topics: Animals; Choice Behavior; Cocaine; Compulsive Behavior; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug-Seeking Behavior; Rats; Rats, Wistar; Reward; Saccharin; Self Administration; Substance Abuse Detection; Sweetening Agents; Time Factors | 2013 |
Different populations of subthalamic neurons encode cocaine vs. sucrose reward and predict future error.
Topics: Adaptation, Psychological; Animals; Cocaine; Cues; Discrimination, Psychological; Male; Neurons; Rats; Rats, Long-Evans; Reward; Subthalamic Nucleus; Sucrose | 2013 |
Intervention effects on kindergarten and first-grade teachers' classroom food practices and food-related beliefs in American Indian reservation schools.
Topics: Candy; Child; Child Nutrition Sciences; Child, Preschool; Faculty; Female; Food Dispensers, Automatic; Food Preferences; Health Knowledge, Attitudes, Practice; Health Promotion; Humans; Indians, North American; Male; Obesity; Prospective Studies; Reward; Role; Schools; Surveys and Questionnaires | 2013 |
Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Metabolic Networks and Pathways; Metabolome; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2014 |
Effects of conditional central expression of HIV-1 tat protein to potentiate cocaine-mediated psychostimulation and reward among male mice.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Drug Synergism; Gene Expression Regulation; HIV-1; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reward; tat Gene Products, Human Immunodeficiency Virus | 2014 |
Facilitation of voluntary goal-directed action by reward cues.
Topics: Adolescent; Adult; Cacao; Candy; Conditioning, Classical; Cues; Female; Goals; Humans; Male; Motivation; Reward; Transfer, Psychology; Young Adult | 2013 |
Cue-evoked cocaine "craving": role of dopamine in the accumbens core.
Topics: Amphetamine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dopamine; Dopamine Antagonists; Drug-Seeking Behavior; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2013 |
Comparison of the behavioral effects of bupropion and psychostimulants.
Topics: Animals; Behavior, Animal; Bupropion; Cocaine; Male; Methamphetamine; Mice; Motor Activity; Psychotropic Drugs; Reward; Substance-Related Disorders | 2013 |
Unique genetic factors influence sensitivity to the rewarding and aversive effects of methamphetamine versus cocaine.
Topics: Animals; Association Learning; Avoidance Learning; Central Nervous System Stimulants; Cocaine; Female; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Reward; Species Specificity | 2013 |
A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Binding, Competitive; Cocaine; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Inhibitory Concentration 50; Male; Motor Activity; Nitriles; Piperidines; Pyridines; Random Allocation; Rats; Receptor, Metabotropic Glutamate 5; Reinforcement Schedule; Reward; Secondary Prevention; Self Administration; Sucrose; Thiazoles | 2014 |
Age-dependent alterations in reward-seeking behavior after brief nicotine exposure.
Topics: Aging; Animals; Appetitive Behavior; Catheters, Indwelling; Cocaine; Conditioning, Operant; Dietary Sucrose; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Nicotine; Nicotinic Agonists; Rats, Sprague-Dawley; Reward; Self Administration | 2014 |
Cocaine self-administration abolishes associative neural encoding in the nucleus accumbens necessary for higher-order learning.
Topics: Action Potentials; Animals; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Male; Neurons; Nucleus Accumbens; Rats; Reward; Self Administration | 2014 |
L-isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors.
Topics: Animals; Behavior, Animal; Berberine Alkaloids; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corydalis; Cyclic AMP; Dopamine Agonists; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Male; Mice; Motor Activity; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward | 2013 |
Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Cues; Drug-Seeking Behavior; Ethanol; Male; Maze Learning; Memory; Morphine; Motor Activity; Protein Kinase Inhibitors; Rats; Reward; Sirolimus | 2014 |
Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action.
Topics: Animals; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Reward; Signal Transduction; Sirtuin 1; Sirtuin 2 | 2013 |
Critical role of peripheral drug actions in experience-dependent changes in nucleus accumbens glutamate release induced by intravenous cocaine.
Topics: Animals; Behavior, Animal; Biosensing Techniques; Blood-Brain Barrier; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Electrochemistry; Glutamic Acid; Injections, Intravenous; Male; Nucleus Accumbens; Peripheral Nervous System; Rats; Rats, Long-Evans; Reward; Self Administration; Substance-Related Disorders | 2014 |
Withdrawal from extended-access cocaine self-administration results in dysregulated functional activity and altered locomotor activity in rats.
Topics: Animals; Attention; Brain; Cocaine; Cocaine-Related Disorders; Glucose; Learning; Locomotion; Male; Memory; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Sleep; Substance Withdrawal Syndrome | 2013 |
Endocannabinoids promote cocaine-induced impulsivity and its rapid dopaminergic correlates.
Topics: Animals; Cannabinoid Receptor Antagonists; Cocaine; Conditioning, Operant; Cues; Dopamine; Dopaminergic Neurons; Endocannabinoids; Impulsive Behavior; Male; Motor Activity; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Time Factors | 2014 |
Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Electric Stimulation; Male; Piperazines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reward | 2014 |
Cocaine-associated odor cue re-exposure increases blood oxygenation level dependent signal in memory and reward regions of the maternal rat brain.
Topics: Animals; Animals, Newborn; Brain; Cocaine; Conditioning, Psychological; Cues; Female; Humans; Magnetic Resonance Imaging; Maternal Behavior; Memory; Odorants; Oxygen; Pregnancy; Rats; Rats, Long-Evans; Reward; Smell | 2014 |
Assessment of reinforcement enhancing effects of toluene vapor and nitrous oxide in intracranial self-stimulation.
Topics: Administration, Inhalation; Animals; Cocaine; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Gases; Illicit Drugs; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Nitrous Oxide; Reinforcement Schedule; Reinforcement, Psychology; Reward; Self Stimulation; Toluene; Volatilization | 2014 |
Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Blotting, Western; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; Immunoenzyme Techniques; Male; Mice; Mice, Knockout; Motor Activity; Muscarinic Antagonists; Piperazines; Pyridines; Quinolones; Receptor, Metabotropic Glutamate 5; Reward; Trihexyphenidyl; Tyrosine 3-Monooxygenase | 2013 |
Initial d2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Gene Expression; Male; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration | 2013 |
Chronic wheel running affects cocaine-induced c-Fos expression in brain reward areas in rats.
Topics: Animals; Brain; Cell Count; Cocaine; Dopamine Uptake Inhibitors; Female; Gene Expression Regulation; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward; Running; Time Factors | 2014 |
Conditioned rewarding effects of morphine and methadone in mice pre-exposed to cocaine.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Motivation; Reward; Time Factors | 2013 |
Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Reward; Self Administration; Sweetening Agents; Urea | 2014 |
Behavior of knock-in mice with a cocaine-insensitive dopamine transporter after virogenetic restoration of cocaine sensitivity in the striatum.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Knock-In Techniques; HEK293 Cells; Humans; Mice; Mice, Transgenic; Nucleus Accumbens; Psychomotor Agitation; Reward; Space Perception | 2014 |
The effects of prenatal cocaine, post-weaning housing and sex on conditioned place preference in adolescent rats.
Topics: Animals; Body Weight; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Housing, Animal; Male; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Reward; Sex Characteristics; Social Isolation; Space Perception | 2014 |
Deletion of the GABAA α2-subunit does not alter self administration of cocaine or reinstatement of cocaine seeking.
Topics: Animals; Cocaine; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, GABA-A; Reinforcement, Psychology; Reward; Self Administration | 2014 |
A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study.
Topics: Adolescent; Adult; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Receptors, Dopamine D2; Reward | 2014 |
Kids, candy, brain and behavior: age differences in responses to candy gains and losses.
Topics: Adult; Age Factors; Aging; Analysis of Variance; Brain; Brain Mapping; Candy; Cerebral Cortex; Child; Child Behavior; Feedback, Psychological; Female; Games, Experimental; Humans; Magnetic Resonance Imaging; Male; Motivation; Neostriatum; Reaction Time; Reward; Surveys and Questionnaires; Young Adult | 2014 |
Random-ratio schedules produce greater demand for i.v. drug administration than fixed-ratio schedules in rhesus monkeys.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Ketamine; Macaca mulatta; Male; Motivation; Piperidines; Reinforcement Schedule; Remifentanil; Reward; Self Administration; Substance-Related Disorders | 2014 |
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking.
Topics: Animals; Basal Ganglia; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopaminergic Neurons; Male; Neural Inhibition; Neural Pathways; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine; Recurrence; Reward; Ventral Tegmental Area | 2014 |
Drug versus sweet reward: greater attraction to and preference for sweet versus drug cues.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Heroin; Lighting; Male; Motivation; Narcotics; Rats, Wistar; Reinforcement, Psychology; Reward; Saccharin; Sweetening Agents; Taste | 2015 |
The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression.
Topics: Acetylcysteine; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration | 2014 |
Beta-2 adrenergic receptors mediate stress-evoked reinstatement of cocaine-induced conditioned place preference and increases in CRF mRNA in the bed nucleus of the stria terminalis in mice.
Topics: Adrenergic beta-Agonists; Animals; Behavior, Addictive; Clenbuterol; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Mice; Pyrimidines; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Corticotropin-Releasing Hormone; Recurrence; Reward; Self Administration; Septal Nuclei; Stress, Psychological | 2014 |
The novel dopamine D3 receptor antagonist, SR 21502, reduces cocaine conditioned place preference in rats.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Cues; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavior; Imidazoles; Male; Pyridines; Rats, Long-Evans; Reward | 2014 |
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area.
Topics: Animals; Cocaine; Dopaminergic Neurons; Dynorphins; Hypothalamus; Impulsive Behavior; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropeptides; Neurotransmitter Agents; Orexin Receptors; Orexins; Reward; Self Administration; Synaptic Transmission; Ventral Tegmental Area | 2014 |
Extinction of a cocaine-taking context that protects against drug-primed reinstatement is dependent on the metabotropic glutamate 5 receptor.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Pyridines; Receptor, Metabotropic Glutamate 5; Recurrence; Reward; Self Administration; Thiazoles | 2015 |
Cell-type specific expression of p11 controls cocaine reward.
Topics: Animals; Annexin A2; Cocaine; Conditioning, Psychological; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Reward; S100 Proteins | 2014 |
Decision-making impairment predicts 3-month hair-indexed cocaine relapse.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognition; Decision Making; Female; Gambling; Hair; Humans; Intelligence Tests; Male; Neuropsychological Tests; Punishment; Recurrence; Reward; Sensitivity and Specificity | 2014 |
The self-administration of rapidly delivered cocaine promotes increased motivation to take the drug: contributions of prior levels of operant responding and cocaine intake.
Topics: Animals; Behavior, Addictive; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Motivation; Rats; Rats, Wistar; Receptor, trkB; Reward; Self Administration | 2014 |
Tolerance to cocaine in brain stimulation reward following continuous cocaine infusions.
Topics: Animals; Brain; Cocaine; Drug Tolerance; Infusion Pumps; Male; Rats; Rats, Long-Evans; Reward; Self Stimulation | 2014 |
Effects of the neuroactive steroid allopregnanolone on intracranial self-stimulation in C57BL/6J mice.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Pregnanolone; Reward; Self Stimulation | 2014 |
Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter.
Topics: Animals; Brain; Cocaine; Conditioning, Psychological; Dependovirus; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Gene Knockout Techniques; Genetic Vectors; Immunohistochemistry; Male; Mice, Transgenic; Motor Activity; Reward; Spatial Behavior | 2014 |
Capacity of novelty-induced locomotor activity and the hole-board test to predict sensitivity to the conditioned rewarding effects of cocaine.
Topics: Age Factors; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Linear Models; Male; Mice; Motor Activity; Reaction Time; Reward | 2014 |
Higher sensitivity to the conditioned rewarding effects of cocaine and MDMA in High-Novelty-Seekers mice exposed to a cocaine binge during adolescence.
Topics: Age Factors; Animals; Cocaine; Conditioning, Psychological; Exploratory Behavior; Male; Maze Learning; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward | 2015 |
Executive dysfunction and reward dysregulation: a high-density electrical mapping study in cocaine abusers.
Topics: Adult; Anhedonia; Brain; Cocaine; Cocaine-Related Disorders; Cognition; Dopamine Uptake Inhibitors; Evoked Potentials; Executive Function; Female; Humans; Inhibition, Psychological; Male; Neuropsychological Tests; Regression Analysis; Reward; Severity of Illness Index; Surveys and Questionnaires | 2014 |
Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or food.
Topics: Animals; Brain; Cell Adhesion Molecules, Neuronal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Eating; Extracellular Matrix Proteins; Food Deprivation; Gene Expression; Glutamate Decarboxylase; Male; Memory; Methyl-CpG-Binding Protein 2; Nerve Tissue Proteins; Protein Phosphatase 1; Random Allocation; Rats, Wistar; Reelin Protein; Reward; Self Administration; Serine Endopeptidases; Volition | 2014 |
Kappa opioid receptor activation potentiates the cocaine-induced increase in evoked dopamine release recorded in vivo in the mouse nucleus accumbens.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Dopamine; Electric Stimulation; Follow-Up Studies; Male; Medial Forebrain Bundle; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Receptors, Opioid, kappa; Reward; Time Factors | 2014 |
On the role of adenosine (A)₂A receptors in cocaine-induced reward: a pharmacological and neurochemical analysis in rats.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Basal Forebrain; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Nucleus Accumbens; Phenethylamines; Purines; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reinforcement, Psychology; Reward; Self Administration; Triazoles | 2015 |
Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Conotoxins; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Food; Lithium Chloride; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Reward; Spatial Behavior | 2015 |
Cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens.
Topics: Afferent Pathways; Amygdala; Animals; Behavior, Animal; Cocaine; Dendritic Spines; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Female; Male; Mice, Mutant Strains; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Organ Culture Techniques; Receptors, N-Methyl-D-Aspartate; Reward | 2014 |
The role of avoidance and inflexibility in characterizing response to contingency management for cocaine use disorders: A secondary profile analysis.
Topics: Adolescent; Adult; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Female; Humans; Male; Middle Aged; Reinforcement, Psychology; Reward; Treatment Outcome; Young Adult | 2015 |
Overlapping patterns of brain activation to food and cocaine cues in cocaine abusers: association to striatal D2/D3 receptors.
Topics: Adult; Body Mass Index; Brain; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Antagonists; Food; Humans; Image Processing, Computer-Assisted; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Oxygen; Photic Stimulation; Positron-Emission Tomography; Raclopride; Reproducibility of Results; Reward | 2015 |
Dynamics of rapid dopamine release in the nucleus accumbens during goal-directed behaviors for cocaine versus natural rewards.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dietary Sucrose; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Food; Goals; Male; Nucleus Accumbens; Psychomotor Performance; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration | 2014 |
Intra-ventral tegmental area microinjections of urotensin II modulate the effects of cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine; Drug-Seeking Behavior; Microinjections; Neural Pathways; Neurons; Nucleus Accumbens; Peptide Hormones; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reward; Sulfonamides; Urotensins; Ventral Tegmental Area | 2015 |
Activity-regulated gene expression in immature neurons in the dentate gyrus following re-exposure to a cocaine-paired environment.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cocaine; Conditioning, Operant; Dentate Gyrus; Dopamine Uptake Inhibitors; Doublecortin Domain Proteins; Doublecortin Protein; Gene Expression Regulation; Male; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reward | 2015 |
[Neurons in NAc core and BLA are activated during cocaine context-associated reward memory retrieval in mice].
Topics: Animals; Basolateral Nuclear Complex; Cocaine; Conditioning, Psychological; Early Growth Response Protein 1; Hippocampus; Memory; Mice; Mice, Inbred C57BL; Neurons; Nucleus Accumbens; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Reward | 2014 |
Variations in the stimulus salience of cocaine reward influences drug-associated contextual memory.
Topics: Aminoacetonitrile; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Piperidines; Receptors, N-Methyl-D-Aspartate; Reward | 2016 |
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice.
Topics: Action Potentials; Animals; Appetitive Behavior; Cannabinoids; Cocaine; Cocaine-Related Disorders; Dopamine; Dopaminergic Neurons; Feeding Behavior; Indoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microinjections; Nerve Tissue Proteins; Neuroglia; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reward; RNA, Messenger; Self Administration; Spleen; Ventral Tegmental Area | 2014 |
Reductions of p11 and 5-HT1B receptor availability in limbic brain regions in cocaine dependence.
Topics: Animals; Annexin A2; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Female; Humans; Male; Neurons; Nucleus Accumbens; Receptor, Serotonin, 5-HT1B; Reward; S100 Proteins | 2014 |
Direct regulation of diurnal Drd3 expression and cocaine reward by NPAS2.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Circadian Rhythm; CLOCK Proteins; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D3; Reward; Space Perception | 2015 |
Eating and inflicting pain out of boredom.
Topics: Boredom; Cacao; Candy; Eating; Emotions; Female; Humans; Male; Motivation; Pain; Random Allocation; Reinforcement, Psychology; Reward; Young Adult | 2015 |
Cocaine-induced suppression of saccharin intake and morphine modulation of Ca²⁺ channel currents in sensory neurons of OPRM1 A118G mice.
Topics: Animals; Behavior, Addictive; Calcium Channels; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Humans; Male; Mice, Transgenic; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Reward; Saccharin; Sensory Receptor Cells; Substance Withdrawal Syndrome; Trigeminal Ganglion | 2015 |
Pharmacological inactivation of the prelimbic cortex emulates compulsive reward seeking in rats.
Topics: Animals; Baclofen; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Decision Making; Dietary Sucrose; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Executive Function; GABA Agonists; Goals; Impulsive Behavior; Male; Muscimol; Rats, Wistar; Reward | 2015 |
Exogenous GM1 ganglioside increases accumbal BDNF levels in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Operant; G(M1) Ganglioside; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reward | 2015 |
Post-training cocaine administration facilitates habit learning and requires the infralimbic cortex and dorsolateral striatum.
Topics: Animals; Cocaine; Conditioning, Operant; Extinction, Psychological; Habits; Learning; Male; Neostriatum; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward | 2015 |
Stereochemistry and neuropharmacology of a 'bath salt' cathinone: S-enantiomer of mephedrone reduces cocaine-induced reward and withdrawal in invertebrates.
Topics: Animals; Cocaine; Conditioning, Psychological; Methamphetamine; Movement; Planarians; Reward; Stereotyped Behavior; Substance Withdrawal Syndrome | 2015 |
Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats.
Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dietary Sucrose; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Female; Male; Methylphenidate; Motivation; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar; Reward | 2014 |
Temporal regulation of peripheral BDNF levels during cocaine and morphine withdrawal: comparison with a natural reward.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome | 2014 |
Sign-tracking predicts increased choice of cocaine over food in rats.
Topics: Animal Feed; Animals; Behavior, Addictive; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Classical; Cues; Male; Motivation; Rats; Rats, Long-Evans; Reward | 2015 |
Didehydro-cortistatin A inhibits HIV-1 Tat mediated neuroinflammation and prevents potentiation of cocaine reward in Tat transgenic mice.
Topics: Animals; Anti-HIV Agents; Chemokines; Cocaine; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Heterocyclic Compounds, 4 or More Rings; HIV Infections; HIV-1; Inflammation; Isoquinolines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurocognitive Disorders; Reward; tat Gene Products, Human Immunodeficiency Virus | 2015 |
Effects of prior cocaine versus morphine or heroin self-administration on extinction learning driven by overexpectation versus omission of reward.
Topics: Animals; Cocaine; Conditioning, Classical; Drug-Seeking Behavior; Extinction, Psychological; Heroin; Morphine; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reward; Self Administration | 2015 |
DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling.
Topics: Animals; Cells, Cultured; Cocaine; Dopamine Plasma Membrane Transport Proteins; Interleukin-1beta; Male; Mice; Mice, Inbred C3H; Mutation; Naloxone; Narcotic Antagonists; Neuroglia; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; RNA, Messenger; Self Administration; Signal Transduction; Toll-Like Receptor 4; Ventral Tegmental Area | 2015 |
On the positive and negative affective responses to cocaine and their relation to drug self-administration in rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Self Administration | 2015 |
Levamisole enhances the rewarding and locomotor-activating effects of cocaine in rats.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Synergism; Levamisole; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward | 2015 |
Cocaine enhances the conditioned rewarding effects of MDMA in adolescent mice.
Topics: Animals; Biogenic Monoamines; Cocaine; Conditioning, Psychological; Drug Synergism; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward | 2015 |
Stress increases cue-triggered "wanting" for sweet reward in humans.
Topics: Adult; Analysis of Variance; Candy; Conditioning, Classical; Conditioning, Operant; Cues; Female; Humans; Male; Motivation; Odorants; Reward; Stress, Psychological; Sweetening Agents; Transfer, Psychology; Visual Analog Scale; Young Adult | 2015 |
Examination of cocaine dose in a preclinical model of natural reward devaluation by cocaine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Male; Models, Animal; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration; Taste Perception; Video Recording | 2015 |
Reward and Toxicity of Cocaine Metabolites Generated by Cocaine Hydrolase.
Topics: Animals; Benzoic Acid; Butyrylcholinesterase; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Genetic Therapy; HEK293 Cells; Humans; Hydrolases; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Reward | 2015 |
Role of basolateral amygdala dopamine D2 receptors in impulsive choice in acute cocaine-treated rats.
Topics: Animals; Basolateral Nuclear Complex; Benzazepines; Choice Behavior; Cocaine; Delay Discounting; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Impulsive Behavior; Male; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Salicylamides | 2015 |
Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats.
Topics: Amphetamine; Animals; Cocaine; Decision Making; Dopamine; Dopamine Agents; Frontal Lobe; Male; Neuropsychological Tests; Nucleus Accumbens; Oxidopamine; Probability; Rats; Reward; Risk-Taking | 2015 |
Enduring effects of tacrine on cocaine-reinforced behavior: Analysis by conditioned-place preference, temporal separation from drug reward, and reinstatement.
Topics: Animals; Cholinergic Agonists; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Food; Infusion Pumps; Kidney; Liver; Male; Motor Activity; Nootropic Agents; Rats; Rats, Wistar; Reward; Self Administration; Tacrine | 2015 |
Sex differences in the long-lasting consequences of adolescent ethanol exposure for the rewarding effects of cocaine in mice.
Topics: Adolescent; Age Factors; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Ethanol; Female; Humans; Male; Mice; Motor Activity; Reward; Self Administration; Sex Characteristics | 2015 |
Circuit-dependent striatal PKA and ERK signaling underlies rapid behavioral shift in mating reaction of male mice.
Topics: Animals; Cocaine; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Electroshock; Female; Fluorescence Resonance Energy Transfer; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Sexual Behavior, Animal | 2015 |
Subthalamic nucleus high-frequency stimulation modulates neuronal reactivity to cocaine within the reward circuit.
Topics: Animals; Basolateral Nuclear Complex; Cocaine; Corpus Striatum; Cytoskeletal Proteins; Electric Stimulation; Globus Pallidus; Male; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Reward; Subthalamic Nucleus | 2015 |
Acute social defeat stress increases the conditioned rewarding effects of cocaine in adult but not in adolescent mice.
Topics: Aggression; Aging; Agonistic Behavior; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Mice; Reward; Stress, Psychological | 2015 |
dcc Haploinsufficiency results in blunted sensitivity to cocaine enhancement of reward seeking.
Topics: Animals; Cocaine; DCC Receptor; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Haploinsufficiency; Hypothalamic Area, Lateral; Implantable Neurostimulators; Male; Mice, Transgenic; Receptors, Cell Surface; Reward; Self Stimulation; Tumor Suppressor Proteins | 2016 |
Delay and probability discounting of sexual and monetary outcomes in individuals with cocaine use disorders and matched controls.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Condoms; Delay Discounting; Economics, Behavioral; Female; Humans; Impulsive Behavior; Male; Probability; Reward; Risk; Safe Sex; Sexual Behavior; Sexual Partners; Sexually Transmitted Diseases; Unsafe Sex | 2015 |
Microglia disrupt mesolimbic reward circuitry in chronic pain.
Topics: Animals; Area Under Curve; Chronic Pain; Cocaine; Conditioning, Classical; Disease Models, Animal; Glutamate Decarboxylase; Hyperalgesia; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Minocycline; Morphine; Nerve Net; Nucleus Accumbens; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward; Sciatic Neuropathy; Ventral Tegmental Area | 2015 |
Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds.
Topics: Analysis of Variance; Animals; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Oxazoles; Rats; Rats, Long-Evans; Receptors, G-Protein-Coupled; Reward; Self Administration; Ventral Tegmental Area | 2015 |
Assessing contributions of nucleus accumbens shell subregions to reward-seeking behavior.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Operant; Extinction, Psychological; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2015 |
[Hell after the pleasure: drug-induced negative symptoms involve lateral habenula].
Topics: Animals; Anxiety; Avoidance Learning; Brain Mapping; Cocaine; Cocaine-Related Disorders; Depression; Dopaminergic Neurons; Efferent Pathways; Habenula; Humans; Models, Neurological; Motor Activity; Neuronal Plasticity; Pleasure; Protein Transport; Rats; Receptors, AMPA; Receptors, Dopamine; Reward; Substance Withdrawal Syndrome; Ventral Tegmental Area | 2015 |
Brief cognitive training interventions in young adulthood promote long-term resilience to drug-seeking behavior.
Topics: Aging; Animals; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Mice, Inbred C57BL; Motor Activity; Resilience, Psychological; Reward; Spatial Behavior | 2015 |
Differences in bingeing behavior and cocaine reward following intermittent access to sucrose, glucose or fructose solutions.
Topics: Animals; Bulimia; Cocaine; Conditioning, Psychological; Eating; Feeding Behavior; Fructose; Glucose; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Sucrose | 2015 |
Adolescent-onset GABAA α1 silencing regulates reward-related decision making.
Topics: Age Factors; Animals; Cocaine; Conditioning, Operant; Decision Making; Dopamine Uptake Inhibitors; Food; Green Fluorescent Proteins; HSP70 Heat-Shock Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prefrontal Cortex; Receptors, GABA-A; Reward; Self Administration | 2015 |
Sex and strain influence attribution of incentive salience to reward cues in mice.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cues; Female; Male; Mice; Motivation; Reward; Self Administration; Sexual Behavior | 2015 |
Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder.
Topics: Anhedonia; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Self Administration; Stress Disorders, Post-Traumatic | 2015 |
Choosing Under the Influence: A Drug-Specific Mechanism by Which the Setting Controls Drug Choices in Rats.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drinking Behavior; Drinking Water; Follow-Up Studies; Food Deprivation; Heroin; Male; Narcotics; Rats, Wistar; Reward; Saccharin; Self Administration; Spatial Behavior; Taste Perception; Time Factors | 2016 |
Aberrant approach-avoidance conflict resolution following repeated cocaine pre-exposure.
Topics: Animals; Avoidance Learning; Cocaine; Conflict, Psychological; Cues; Male; Motivation; Rats; Rats, Long-Evans; Reinforcement, Psychology; Reward | 2015 |
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological | 2015 |
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; GABAergic Neurons; K Cl- Cotransporters; Male; Mice; Mice, Inbred C57BL; Microglia; Models, Neurological; Morphine; Neuroimmunomodulation; Reward; Substance Withdrawal Syndrome; Symporters; Ventral Thalamic Nuclei | 2016 |
Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release.
Topics: Affect; Animals; Cocaine; Diterpenes, Clerodane; Dopamine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Time Factors; Ventral Tegmental Area | 2016 |
Reciprocal Inhibitory Interactions Between the Reward-Related Effects of Leptin and Cocaine.
Topics: Animals; Cocaine; Conditioning, Classical; Dopamine; Drug-Seeking Behavior; Extinction, Psychological; Leptin; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Signal Transduction; Ventral Tegmental Area | 2016 |
Adolescent nicotine exposure fails to impact cocaine reward, aversion and self-administration in adult male rats.
Topics: Age Factors; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Male; Nicotine; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2015 |
Cocaine-induced reward enhancement measured with intracranial self-stimulation in rats bred for low versus high saccharin intake.
Topics: Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Food Preferences; Male; Rats; Reward; Saccharin; Self Stimulation; Substance-Related Disorders; Sweetening Agents | 2016 |
Diet-induced obesity causes ghrelin resistance in reward processing tasks.
Topics: Animals; Cocaine; Conditioning, Operant; Diet, High-Fat; Dopamine; Dopamine Uptake Inhibitors; Ghrelin; Mice; Mice, Knockout; Neurons; Obesity; Reward; Saccharin; Ventral Tegmental Area | 2015 |
Social interaction reward decreases p38 activation in the nucleus accumbens shell of rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Fluorescent Antibody Technique; Male; Neurons; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Psychological Tests; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reward; Social Behavior; Spatial Behavior; Stress, Psychological; Time Factors | 2015 |
5-HT1A Autoreceptors in the Dorsal Raphe Nucleus Convey Vulnerability to Compulsive Cocaine Seeking.
Topics: Animals; Autoreceptors; Cocaine; Compulsive Behavior; Conditioning, Classical; Designer Drugs; Dorsal Raphe Nucleus; Drug-Seeking Behavior; Gene Knockdown Techniques; Male; Mice; Motivation; Neural Pathways; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Reward; Serotonergic Neurons; Serotonin 5-HT1 Receptor Antagonists | 2016 |
Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior.
Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Morphinans; Naltrexone; Nociception; Nuclear Receptor Subfamily 1, Group F, Member 1; Random Allocation; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Spatial Behavior | 2015 |
Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area.
Topics: Animals; Arachidonic Acids; Biological Transport; Calcium; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Endocannabinoids; gamma-Aminobutyric Acid; Gene Expression Regulation; Glycerides; GTP-Binding Protein alpha Subunits, Gq-G11; Male; Norepinephrine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Adrenergic, alpha-1; Receptors, GABA; Receptors, Metabotropic Glutamate; Reward; Synaptic Transmission; Type C Phospholipases; Ventral Tegmental Area | 2015 |
Abnormal context-reward associations in an immune-mediated neurodevelopmental mouse model with relevance to schizophrenia.
Topics: Animals; Cocaine; Conditioning, Psychological; Disease Models, Animal; Fear; Female; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Reward; Schizophrenia; Sucrose | 2015 |
Fluoxetine exposure during adolescence increases preference for cocaine in adulthood.
Topics: Age Factors; Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Food Preferences; Male; Mice, Inbred C57BL; Reward; Selective Serotonin Reuptake Inhibitors; Time Factors | 2015 |
Transient inactivation of the posterior paraventricular nucleus of the thalamus blocks cocaine-seeking behavior.
Topics: Animals; Baclofen; Cocaine; Conditioning, Psychological; Cues; Discrimination, Psychological; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats, Wistar; Reward; Self Administration | 2015 |
Endocannabinoid signaling mediates oxytocin-driven social reward.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Autism Spectrum Disorder; Benzamides; Benzodiazepines; Camphanes; Carbamates; Clozapine; Cocaine; Endocannabinoids; Immunohistochemistry; Infusions, Intraventricular; Lipids; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Oxytocin; Piperazines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Reward; Signal Transduction; Social Behavior | 2015 |
Transplantation of human retinal pigment epithelial cells in the nucleus accumbens of cocaine self-administering rats provides protection from seeking.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopaminergic Neurons; Drug-Seeking Behavior; Epithelial Cells; Extinction, Psychological; Humans; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Retinal Pigment Epithelium; Retinal Pigments; Reward; Self Administration; Substance-Related Disorders; Ventral Tegmental Area | 2016 |
Acute effects of cocaine and cannabis on reversal learning as a function of COMT and DRD2 genotype.
Topics: Adolescent; Adult; Attention; Cannabis; Catechol O-Methyltransferase; Cocaine; Double-Blind Method; Female; Genetic Variation; Humans; Male; Neuropsychological Tests; Punishment; Receptors, Dopamine D2; Reversal Learning; Reward; Substance-Related Disorders; Young Adult | 2016 |
DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons.
Topics: Animals; Behavior, Animal; Brain; Caffeine; Calmodulin-Binding Proteins; Central Nervous System Stimulants; Chlorocebus aethiops; Cocaine; COS Cells; Dendritic Spines; Dopamine and cAMP-Regulated Phosphoprotein 32; Environment; Fluorescence Recovery After Photobleaching; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mutation; Neostriatum; Neurons; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Reward | 2015 |
Drug-motivated behavior in rats with lesions of the thalamic orosensory area.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Body Weight; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Male; Motivation; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Statistics as Topic; Sweetening Agents; Taste; Taste Perception; Thalamus | 2016 |
NMDA and dopamine D1 receptors within NAc-shell regulate IEG proteins expression in reward circuit during cocaine memory reconsolidation.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Genes, Immediate-Early; Male; Memory; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Propranolol; Proto-Oncogene Proteins c-fos; Raclopride; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reward; Spatial Behavior | 2016 |
Cocaine Self-Administration Experience Induces Pathological Phasic Accumbens Dopamine Signals and Abnormal Incentive Behaviors in Drug-Abstinent Rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Medication; Synaptic Transmission | 2016 |
Activation of D1/5 Dopamine Receptors: A Common Mechanism for Enhancing Extinction of Fear and Reward-Seeking Behaviors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; beta-Arrestins; Cocaine; Conditioning, Classical; Cyclic AMP; Extinction, Psychological; Fear; Male; Mice, Inbred C57BL; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward | 2016 |
Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys.
Topics: Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Drug-Seeking Behavior; Endocannabinoids; Male; Nicotine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Reinforcement, Psychology; Reward; Rimonabant; Saimiri; Self Administration | 2016 |
Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Topics: Action Potentials; Animals; Benzazepines; Cocaine; Colforsin; Corpus Striatum; Cyclic AMP-Dependent Protein Kinases; Dopamine; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Mice; Mice, Knockout; Neurons; Nucleus Accumbens; Phosphoproteins; Phosphorylation; Proteome; Proteomics; rap1 GTP-Binding Proteins; Receptors, Dopamine D1; Reward; Signal Transduction | 2016 |
Early adolescent nicotine exposure affects later-life cocaine reward in mice.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Eating; Male; Mice; Mice, Inbred ICR; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Reward | 2016 |
Effects of Trace Amine-associated Receptor 1 Agonists on the Expression, Reconsolidation, and Extinction of Cocaine Reward Memory.
Topics: Animals; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Locomotion; Male; Memory; Oxazoles; Phenethylamines; Rats; Receptors, G-Protein-Coupled; Reward; Self Administration | 2016 |
In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward.
Topics: Analysis of Variance; Animals; Cocaine; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Immunohistochemistry; Mice, Inbred C57BL; Mice, Transgenic; Neuroimaging; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Signal Transduction | 2016 |
Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats.
Topics: Animals; Cannabidiol; Cocaine; Conditioning, Classical; Cues; Disease Models, Animal; Male; Memory; Mental Recall; Morphine; Naltrexone; Rats; Rats, Wistar; Reward | 2017 |
Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling.
Topics: Actins; Animals; Cocaine; Guanine Nucleotide Exchange Factors; Mice; Neuronal Plasticity; Nucleus Accumbens; Proto-Oncogene Proteins c-akt; rap GTP-Binding Proteins; Reward; Rho Guanine Nucleotide Exchange Factors; Self Administration; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases | 2016 |
Perseveration of craving: effects of stimuli conditioned to drugs of abuse versus conventional reinforcers differing in demand.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Craving; Cues; Dietary Sugars; Disease Models, Animal; Ethanol; Male; Motivation; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Water | 2017 |
A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dietary Fats; Endocannabinoids; Hippocampus; Male; Mice; Mice, Transgenic; Monoacylglycerol Lipases; Nucleus Accumbens; Random Allocation; Receptor, Cannabinoid, CB1; Reward; Signal Transduction; Social Behavior | 2016 |
Effects of Cannabinoid Exposure during Adolescence on the Conditioned Rewarding Effects of WIN 55212-2 and Cocaine in Mice: Influence of the Novelty-Seeking Trait.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cocaine; Conditioning, Classical; Exploratory Behavior; Male; Mice; Morpholines; Naphthalenes; Reward | 2016 |
Clues on the coding of reward cues by the nucleus accumbens.
Topics: Animals; Cocaine; Neurons; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2016 |
The neural encoding of cocaine-induced devaluation in the ventral pallidum.
Topics: Action Potentials; Animals; Avoidance Learning; Basal Forebrain; Cocaine; Cues; Dopamine Uptake Inhibitors; Male; Neurons; Quinine; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Taste Perception | 2016 |
Ultrasonic vocalization in rats self-administering heroin and cocaine in different settings: evidence of substance-specific interactions between drug and setting.
Topics: Analgesics, Opioid; Animals; Cocaine; Dopamine Uptake Inhibitors; Heroin; Male; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Substance-Related Disorders; Ultrasonic Waves; Vocalization, Animal | 2016 |
Female Japanese quail with high levels of estradiol demonstrate cocaine-induced conditioned place preference.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Coturnix; Cues; Dose-Response Relationship, Drug; Estradiol; Female; Reward | 2016 |
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Conditioning, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Reward; Substance-Related Disorders | 2016 |
Long-Term Blockade of Cocaine Self-Administration and Locomotor Activation in Rats by an Adenoviral Vector-Delivered Cocaine Hydrolase.
Topics: Adenoviridae; Animals; Anxiety; Carboxylic Ester Hydrolases; Cocaine; Cocaine-Related Disorders; Diet; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Male; Motor Activity; Rats; Rats, Wistar; Reward; Self Administration; Weight Gain | 2016 |
Loss of the trpc4 gene is associated with a reduction in cocaine self-administration and reduced spontaneous ventral tegmental area dopamine neuronal activity, without deficits in learning for natural rewards.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Female; Gene Expression Regulation; Male; Maze Learning; Membrane Potentials; Rats; Rats, Inbred F344; Rats, Transgenic; Reinforcement Schedule; Reward; Self Administration; Sucrose; TRPC Cation Channels; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2016 |
Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice.
Topics: Animals; Annexin A2; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Extinction, Psychological; Female; Male; Mice; Mice, Inbred C57BL; Motor Activity; Repetition Priming; Reward; S100 Proteins; Sex Factors | 2016 |
Familiar companions diminish cocaine conditioning and attenuate cocaine-stimulated dopamine release in the nucleus accumbens.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Corticosterone; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Friends; In Vitro Techniques; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward | 2016 |
Adolescent Traumatic Brain Injury Induces Chronic Mesolimbic Neuroinflammation with Concurrent Enhancement in the Rewarding Effects of Cocaine in Mice during Adulthood.
Topics: Age Factors; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Cocaine; Conditioning, Psychological; Inflammation; Inflammation Mediators; Limbic System; Locomotion; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Self Administration | 2017 |
BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli.
Topics: Adenosine Triphosphatases; Animals; Behavior, Animal; Chromatin; Chromosomal Proteins, Non-Histone; Cocaine; Emotions; Epigenesis, Genetic; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Social Environment; Stress, Psychological; Transcription Factors | 2016 |
Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cyclin-Dependent Kinase 5; Epigenesis, Genetic; Histones; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Rats; Reward; Zinc Fingers | 2016 |
Epac Signaling Is Required for Cocaine-Induced Change in AMPA Receptor Subunit Composition in the Ventral Tegmental Area.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cocaine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Excitatory Postsynaptic Potentials; Female; Male; Mice; Mice, Knockout; Neurons; Patch-Clamp Techniques; Receptors, AMPA; Reward; Synapses; Thionucleotides; Ventral Tegmental Area | 2016 |
Region-specific effects of developmental exposure to cocaine on fibroblast growth factor-2 expression in the rat brain.
Topics: Amygdala; Animals; Brain; Cocaine; Dopamine Uptake Inhibitors; Fibroblast Growth Factor 2; Hippocampus; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Ventral Tegmental Area | 2016 |
Neuronal activity and the expression of hypothalamic oxytocin and vasopressin in social versus cocaine conditioning.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Hypothalamus; Immunochemistry; Male; Mice, Inbred ICR; Neurons; Oxytocin; Proto-Oncogene Proteins c-fos; Reward; Social Behavior; Vasopressins | 2016 |
`Up-regulation of histone acetylation induced by social defeat mediates the conditioned rewarding effects of cocaine.
Topics: Acetylation; Animals; Central Nervous System Stimulants; Cerebral Cortex; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dominance-Subordination; Epigenesis, Genetic; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Male; Mice; Reward; Spatial Behavior; Stress, Psychological; Up-Regulation; Valproic Acid | 2016 |
Objective and specific tracking of anhedonia via event-related potentials in individuals with cocaine use disorders.
Topics: Adult; Anhedonia; Brain; Cocaine; Cocaine-Related Disorders; Depressive Disorder; Electroencephalography; Evoked Potentials; Female; Humans; Male; Middle Aged; Motivation; Reward | 2016 |
Caffeine, a common active adulterant of cocaine, enhances the reinforcing effect of cocaine and its motivational value.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Motivation; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Reward; Self Administration | 2016 |
Cocaine withdrawal alters the reward omission effect and enhances traits of negative urgency in rats across multiple days of testing.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome | 2016 |
Carrots and sticks fail to change behavior in cocaine addiction.
Topics: Adult; Avoidance Learning; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Female; Goals; Habits; Humans; Male; Middle Aged; Punishment; Reward | 2016 |
Sex and menstrual cycle effects on chronic oral cocaine self-administration in rhesus monkeys: Effects of a nondrug alternative reward.
Topics: Administration, Oral; Animals; Cocaine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Female; Follicular Phase; Luteal Phase; Macaca mulatta; Male; Menstrual Cycle; Phencyclidine; Reward; Saccharin; Self Administration; Sex Factors; Sweetening Agents | 2016 |
Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation.
Topics: Animals; Cocaine; Female; Gene Expression Regulation; Genes, Transgenic, Suicide; Male; Mice; Mice, Inbred C57BL; Motivation; Nucleus Accumbens; Rats; Receptors, Dopamine D2; Reward | 2016 |
[Sucrose reward promotes rats' motivation for cocaine].
Topics: Animals; Cocaine; Conditioning, Classical; Conditioning, Operant; Memory; Motivation; Rats; Reward; Self Administration; Sucrose | 2016 |
Effects of D1 receptor knockout on fear and reward learning.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Classical; Dopamine Agonists; Dopamine Uptake Inhibitors; Extinction, Psychological; Fear; Female; Generalization, Psychological; Male; Mice; Mice, Knockout; Receptors, Dopamine D1; Receptors, Dopamine D5; Reward | 2016 |
N-acetylcysteine amide (AD4) reduces cocaine-induced reinstatement.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Depression; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration | 2016 |
Role of dopamine neurotransmission in the long-term effects of repeated social defeat on the conditioned rewarding effects of cocaine.
Topics: Age Factors; Animals; Benzazepines; Cerebral Cortex; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hippocampus; Male; Mice; Raclopride; Receptors, Dopamine; Reward; Statistics, Nonparametric; Stress, Psychological | 2016 |
Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Economics, Behavioral; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Time Factors | 2016 |
Effects of 3,4-methylenedioxypyrovalerone (MDPV) pre-exposure on the aversive effects of MDPV, cocaine and lithium chloride: Implications for abuse vulnerability.
Topics: Animals; Avoidance Learning; Benzodioxoles; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Lithium Chloride; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sweetening Agents; Synthetic Cathinone; Taste | 2016 |
Dissociable Effects of Cocaine Dependence on Reward Processes: The Role of Acute Cocaine and Craving.
Topics: Adult; Anticipation, Psychological; Brain; Cocaine; Cocaine-Related Disorders; Craving; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Reward | 2017 |
The infralimbic and prelimbic cortices contribute to the inhibitory control of cocaine-seeking behavior during a discriminative stimulus task in rats.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Discrimination, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward | 2017 |
Action of Pitolisant on the stimulant and rewarding effects of cocaine in mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Piperidines; Reward; Spatial Behavior | 2016 |
Adolescent cocaine self-administration induces habit behavior in adulthood: sex differences and structural consequences.
Topics: Age Factors; Animals; Baclofen; Behavior, Animal; Cocaine; Conditioning, Psychological; Decision Making; Dendritic Spines; Dopamine Uptake Inhibitors; Female; Flavones; GABA-B Receptor Agonists; Male; Mice; Prefrontal Cortex; Receptor, trkB; Reward; Self Administration | 2016 |
Dopamine D1 and D3 receptor interactions in cocaine reward and seeking in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Drug Therapy, Combination; Drug-Seeking Behavior; Fluorenes; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D3; Reinforcement, Psychology; Reward | 2016 |
Topiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness.
Topics: Analysis of Variance; Animals; Anticonvulsants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Fructose; Male; Mice; Reward; Topiramate; Ventral Tegmental Area | 2016 |
Prior Cocaine Experience Impairs Normal Phasic Dopamine Signals of Reward Value in Accumbens Shell.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2017 |
Subanesthetic ketamine decreases the incentive-motivational value of reward-related cues.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Classical; Cues; Drug-Seeking Behavior; Ketamine; Male; Motivation; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward | 2017 |
Emotional, physical and sexual abuse are associated with a heightened limbic response to cocaine cues.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Emotions; Humans; Limbic System; Magnetic Resonance Imaging; Male; Middle Aged; Physical Abuse; Reward; Sex Offenses | 2017 |
The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history.
Topics: Animals; Cocaine; Copulation; Female; Male; Nucleus Accumbens; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Reward; Sexual Behavior, Animal | 2016 |
Effects of bingeing on fat during adolescence on the reinforcing effects of cocaine in adult male mice.
Topics: Animals; Anxiety; Body Weight; Bulimia; Cocaine; Conditioning, Classical; Corticosterone; Diet, High-Fat; Drug-Seeking Behavior; Gene Expression; Ghrelin; Leptin; Male; Mice; Nucleus Accumbens; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Reward; Self Administration; Ventral Tegmental Area | 2017 |
Comparing rewarding and reinforcing properties between 'bath salt' 3,4-methylenedioxypyrovalerone (MDPV) and cocaine using ultrasonic vocalizations in rats.
Topics: Animals; Benzodioxoles; Cocaine; Dopamine Uptake Inhibitors; Male; Pyrrolidines; Rats; Reinforcement, Psychology; Reward; Self Administration; Synthetic Cathinone; Ultrasonic Waves; Vocalization, Animal | 2018 |
Conditioned object preference: an alternative approach to measuring reward learning in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Exploratory Behavior; Extinction, Psychological; Male; Models, Animal; Psychological Tests; Rats, Sprague-Dawley; Reward | 2016 |
Mesolimbic leptin signaling negatively regulates cocaine-conditioned reward.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine; Exons; Leptin; Male; Mice, Knockout; Mice, Obese; Motivation; Nucleus Accumbens; Receptors, Dopamine D2; Receptors, Leptin; Reward; Signal Transduction; Ventral Tegmental Area | 2016 |
Maternal Separation Impairs Cocaine-Induced Behavioural Sensitization in Adolescent Mice.
Topics: Age Factors; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Female; Homeodomain Proteins; Male; Maternal Deprivation; Mice; Motor Activity; Neural Pathways; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Dopamine D2; Reward; Self Administration; Transcription Factors | 2016 |
Comparison of cocaine reinforcement in lean and obese Zucker rats: Relative potency and reinstatement of extinguished operant responding.
Topics: Administration, Intravenous; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Obesity; Psychotropic Drugs; Rats, Zucker; Reward; Self Administration; Species Specificity; Survival Analysis | 2017 |
Differential effects of aprepitant, a clinically used neurokinin-1 receptor antagonist on the expression of conditioned psychostimulant versus opioid reward.
Topics: Amphetamine; Analgesics, Opioid; Animals; Aprepitant; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Reward | 2017 |
Preference for Cocaine is Represented in the Orbitofrontal Cortex by an Increased Proportion of Cocaine Use-Coding Neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Male; Neurons; Prefrontal Cortex; Rats; Rats, Wistar; Reaction Time; Reward; Saccharin | 2018 |
Behavioral evidence for the abuse potential of the novel synthetic cathinone alpha-pyrrolidinopentiothiophenone (PVT) in rodents.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Locomotion; Male; Methamphetamine; Mice; Pyrrolidines; Rats; Reinforcement, Psychology; Reward; Rodentia; Self Administration; Thiophenes | 2017 |
Dopaminergic dynamics underlying sex-specific cocaine reward.
Topics: Animals; Calcium; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Electrophysiology; Estrus; Female; Male; Mice, Inbred C57BL; Reward; Sex Factors; Ventral Tegmental Area | 2017 |
Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior.
Topics: Animals; Cocaine; Dopaminergic Neurons; Female; Gene Knockdown Techniques; Locomotion; Male; Mice; Morphine; Neural Inhibition; Nucleus Accumbens; Receptor, Adenosine A1; Receptors, GABA-A; Receptors, GABA-B; Reward; Synaptic Transmission; Ventral Tegmental Area | 2017 |
KCNQ2/3 channel agonist flupirtine reduces cocaine place preference in rats.
Topics: Aminopyridines; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; KCNQ3 Potassium Channel; Locomotion; Male; Motor Activity; Rats; Receptors, Dopamine; Reward | 2017 |
Bingeing on fat increases cocaine reward.
Topics: Animals; Brain; Brain Mapping; Bulimia; Choice Behavior; Cocaine; Diet, High-Fat; Dopamine; Dopaminergic Neurons; Gene Expression Profiling; Mice; Obesity; Receptors, Opioid, mu; Reward; Substance-Related Disorders | 2017 |
A single cocaine exposure disrupts actin dynamics in the cortico-accumbal pathway of adolescent rats: modulation by a second cocaine injection.
Topics: Actins; Analysis of Variance; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward | 2017 |
Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Psychological; Disease Models, Animal; Goals; Hippocampus; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Reward | 2017 |
Exposure of adolescent mice to 3,4-methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood.
Topics: Animals; Benzodioxoles; Cocaine; Conditioning, Psychological; Humans; Injections, Subcutaneous; Locomotion; Male; Mice; Pyrrolidines; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synthetic Cathinone | 2017 |
The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic.
Topics: Administration, Intravesical; Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extracellular Space; Male; Motor Activity; Nucleus Accumbens; Propylamines; Rats, Long-Evans; Reward; Self Administration | 2017 |
Targeting the subthalamic nucleus in a preclinical model of alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Animals; Cocaine; Ethanol; Male; Motivation; Rats; Reinforcement, Psychology; Reward; Subthalamic Nucleus | 2017 |
Suvorexant, an orexin/hypocretin receptor antagonist, attenuates motivational and hedonic properties of cocaine.
Topics: Animals; Azepines; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Locomotion; Male; Motivation; Orexin Receptor Antagonists; Rats; Reinforcement, Psychology; Reward; Self Administration; Triazoles; Ventral Striatum | 2018 |
Changes in gene expression and sensitivity of cocaine reward produced by a continuous fat diet.
Topics: Animals; Cocaine; Conditioning, Classical; Diet, High-Fat; Gene Expression; Male; Mice; Nucleus Accumbens; Prefrontal Cortex; Receptor, Cannabinoid, CB1; Receptors, Ghrelin; Receptors, Opioid, mu; Reinforcement, Psychology; Reward; Ventral Tegmental Area | 2017 |
Repeated social defeat and the rewarding effects of cocaine in adult and adolescent mice: dopamine transcription factors, proBDNF signaling pathways, and the TrkB receptor in the mesolimbic system.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Classical; Corticosterone; Dopamine; Male; Membrane Glycoproteins; Mice; Nucleus Accumbens; Protein Precursors; Receptor, trkB; Receptors, Dopamine D2; Reward; Stress, Psychological; Transcription Factors; Ventral Tegmental Area | 2017 |
Muscarinic receptor M
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Hyperkinesis; Male; Mice; Mice, Knockout; Pyridazines; Pyridines; Reinforcement, Psychology; Reward; Thiophenes | 2017 |
Altered reward sensitivity in female offspring of cocaine-exposed fathers.
Topics: Amphetamine; Animals; Anxiety; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Fathers; Female; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Phenotype; Reward; Sex Characteristics; Social Behavior | 2017 |
The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling.
Topics: Actins; Animals; Cocaine; Cocaine-Related Disorders; Dendrites; Dendritic Spines; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Myelin and Lymphocyte-Associated Proteolipid Proteins; Neurogenesis; Neurons; Nucleus Accumbens; Reward; Serum Response Factor; Signal Transduction | 2018 |
Opposing Roles of Rapid Dopamine Signaling Across the Rostral-Caudal Axis of the Nucleus Accumbens Shell in Drug-Induced Negative Affect.
Topics: Animals; Avoidance Learning; Channelrhodopsins; Cocaine; Cues; Dopamine; Dopamine Uptake Inhibitors; Light; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Transgenic; Reinforcement, Psychology; Reward; Self Administration; Self Stimulation; Taste; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2017 |
Synthetic cathinones and stereochemistry: S enantiomer of mephedrone reduces anxiety- and depressant-like effects in cocaine- or MDPV-abstinent rats.
Topics: Alkaloids; Animals; Anxiety; Anxiety Disorders; Central Nervous System Stimulants; Cocaine; Dopamine; Locomotion; Male; Methamphetamine; Rats; Reward; Stereoisomerism | 2017 |
Perinatal protein deprivation facilitates morphine cross-sensitization to cocaine and enhances ΔFosB expression in adult rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Gene Expression Regulation; Male; Morphine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward | 2017 |
Prior Cocaine Self-Administration Increases Response-Outcome Encoding That Is Divorced from Actions Selected in Dorsal Lateral Striatum.
Topics: Animals; Choice Behavior; Cocaine; Corpus Striatum; Decision Making; Male; Rats; Rats, Long-Evans; Reaction Time; Reward; Self Administration | 2017 |
Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm.
Topics: Animals; Behavior, Addictive; Central Nervous System Stimulants; Choice Behavior; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Environment; Equipment Design; Extinction, Psychological; Female; Male; Mice, Inbred C57BL; Motor Activity; Neuropsychological Tests; Psychotropic Drugs; Reward; Spatial Behavior; Time Factors | 2017 |
Interaction between trait and housing condition produces differential decision-making toward risk choice in a rat gambling task.
Topics: Animals; Choice Behavior; Cocaine; Decision Making; Gambling; Housing, Animal; Male; Models, Animal; Punishment; Rats, Sprague-Dawley; Reward; Risk-Taking; Social Isolation | 2017 |
Sensitivity to cocaine in adult mice is due to interplay between genetic makeup, early environment and later experience.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Disease Susceptibility; Dopamine Uptake Inhibitors; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Inbred DBA; Proto-Oncogene Proteins c-fos; Random Allocation; Reward; Spatial Behavior; Species Specificity | 2017 |
Susceptibility to traumatic stress sensitizes the dopaminergic response to cocaine and increases motivation for cocaine.
Topics: Animals; Anxiety; Avoidance Learning; Cocaine; Cocaine-Related Disorders; Disease Susceptibility; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Motivation; Motor Activity; Nucleus Accumbens; Predatory Behavior; Rats, Sprague-Dawley; Resilience, Psychological; Reward; Self Administration; Stress, Psychological | 2017 |
Neurochemical evidence that cocaine- and amphetamine-regulated transcript (CART) 55-102 peptide modulates the dopaminergic reward system by decreasing the dopamine release in the mouse nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Extracellular Space; Homovanillic Acid; Humans; Male; Mice; Nerve Tissue Proteins; Norepinephrine; Nucleus Accumbens; Peptide Fragments; Phenylethyl Alcohol; Reward; Tissue Culture Techniques | 2017 |
Chronic treatment with Tempol during acquisition or withdrawal from CPP abolishes the expression of cocaine reward and diminishes oxidative damage.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclic N-Oxides; Disease Models, Animal; Lipid Peroxidation; Male; Nitric Oxide; Nitrites; Oxidative Stress; Prefrontal Cortex; Rats; Reinforcement, Psychology; Reward; Spin Labels; Treatment Outcome | 2017 |
Female rats exhibit less avoidance than male rats of a cocaine-, but not a morphine-paired, saccharin cue.
Topics: Analysis of Variance; Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Corticosterone; Cues; Estrous Cycle; Female; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sex Characteristics; Taste | 2018 |
Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury.
Topics: Aging; Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Cocaine; Dexamethasone; Diagnostic Imaging; Gene Expression Regulation; Immunity; Male; Mice, Inbred C57BL; Monocytes; Neuroglia; Nucleus Accumbens; Phenotype; Reward | 2017 |
A Molecular Code for Imprinting Drug-Cue Associations.
Topics: Cocaine; Cues; Histone Deacetylases; Humans; Reward | 2017 |
The effects of nicotine on conditioning, extinction, and reinstatement in humans.
Topics: Adult; Candy; Conditioning, Psychological; Connecticut; Extinction, Psychological; Female; Ganglionic Stimulants; Humans; Male; Nicotine; Reward; Students; Tobacco Use Disorder; Universities | 2018 |
Differential epigenetic changes in the hippocampus and prefrontal cortex of female mice that had free access to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Epigenesis, Genetic; Female; Hippocampus; Mice, Inbred C57BL; Motor Activity; Prefrontal Cortex; Reward | 2018 |
Corticosterone regulates both naturally occurring and cocaine-induced dopamine signaling by selectively decreasing dopamine uptake.
Topics: Animals; Cocaine; Corticosterone; Dopamine; Dopamine Uptake Inhibitors; Male; Nucleus Accumbens; Rats, Sprague-Dawley; Reward; Signal Transduction | 2017 |
Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Limbic Lobe; Male; Mesencephalon; Motivation; Orexin Receptors; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Signal Transduction; Ventral Tegmental Area | 2018 |
Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function.
Topics: Animals; Behavior, Animal; beta-Arrestins; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Learning; Mice; Mice, Knockout; Neurons; Nucleus Accumbens; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Reward; Self Administration | 2017 |
VTA mTOR Signaling Regulates Dopamine Dynamics, Cocaine-Induced Synaptic Alterations, and Reward.
Topics: Animals; Association Learning; Cocaine; Conditioning, Psychological; Dopamine; Dopamine Plasma Membrane Transport Proteins; GABAergic Neurons; Male; Mice; Mice, Knockout; Microinjections; Neuronal Plasticity; Neurons; Nucleus Accumbens; Reward; Synapses; Synaptic Transmission; TOR Serine-Threonine Kinases; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2018 |
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat.
Topics: Animals; Animals, Outbred Strains; Anxiety; Bulimia; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Corticosterone; Diet, High-Fat; Disease Models, Animal; Dopamine Uptake Inhibitors; Housing, Animal; Leptin; Male; Mice; Random Allocation; Reward; Social Isolation; Spatial Behavior | 2018 |
Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Drug Interactions; Dynorphins; Excitatory Postsynaptic Potentials; Extinction, Psychological; Male; Microinjections; Miniature Postsynaptic Potentials; Naltrexone; Orexins; Paraventricular Hypothalamic Nucleus; Rats; Reward; Self Administration | 2018 |
The Role of Dopaminergic Signaling in the Medial Prefrontal Cortex for the Expression of Cocaine-Induced Conditioned Place Preference in Rats.
Topics: Animals; Channelrhodopsins; Cocaine; Conditioning, Operant; Dopamine; Dopamine D2 Receptor Antagonists; Dopaminergic Neurons; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; Male; Optogenetics; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Signal Transduction; Ventral Tegmental Area | 2017 |
Blockade of NMDA receptors blocks the acquisition of cocaine conditioned approach in rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Male; Rats; Receptors, N-Methyl-D-Aspartate; Reward | 2018 |
Prenatal stress increases adult vulnerability to cocaine reward without affecting pubertal anxiety or novelty response.
Topics: Animals; Anxiety; Anxiety Disorders; Cocaine; Conditioning, Psychological; Exploratory Behavior; Female; Male; Motor Activity; Rats, Wistar; Reward | 2018 |
Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian.
Topics: Animals; Behavior, Addictive; Benzazepines; Cocaine; Conditioning, Classical; Disease Models, Animal; Dopamine Antagonists; Drug Tolerance; Male; Planarians; Reward; Sucrose | 2018 |
Different functional domains measured by cocaine self-administration under the progressive-ratio and punishment schedules in male Wistar rats.
Topics: Animals; Area Under Curve; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Inhibition, Psychological; Male; Motivation; Punishment; Rats; Rats, Wistar; Reward; Sucrose | 2018 |
Appetitive to aversive counter-conditioning as intervention to reduce reinstatement of reward-seeking behavior: the role of the serotonin transporter.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Psychological; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Rats, Inbred Strains; Reinforcement, Psychology; Reward; Self Administration; Serotonin Plasma Membrane Transport Proteins | 2019 |
Estrogen Receptor β in the Nucleus Accumbens Regulates the Rewarding Properties of Cocaine in Female Mice.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mice; Mice, Inbred C57BL; Nitriles; Nucleus Accumbens; Ovariectomy; Propionates; Reward | 2018 |
β-Arrestin-biased β-adrenergic signaling promotes extinction learning of cocaine reward memory.
Topics: Adrenergic beta-Antagonists; Animals; beta-Arrestin 2; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Extinction, Psychological; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Prefrontal Cortex; Propranolol; Reward; Signal Transduction | 2018 |
Cocaine conditioned place preference: unexpected suppression of preference due to testing combined with strong conditioning.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Neurons; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2019 |
Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Locomotion; Mice; Mice, Inbred C57BL; Mice, Knockout; Reward; RGS Proteins; Signal Transduction; Ventral Striatum | 2018 |
Leptin levels and its correlation with crack-cocaine use severity: A preliminary study.
Topics: Adult; Biomarkers; Body Composition; Body Mass Index; Brazil; Cocaine-Related Disorders; Crack Cocaine; Cross-Sectional Studies; Humans; Leptin; Male; Reward; Severity of Illness Index; Young Adult | 2018 |
Intravenous cocaine self-administration in a panel of inbred mouse strains differing in acute locomotor sensitivity to cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Infusions, Intravenous; Locomotion; Male; Mice; Mice, Inbred Strains; Reinforcement, Psychology; Reward; Self Administration | 2018 |
Hypocretin/orexin deficiency decreases cocaine abuse liability.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orexins; Reward; Saccharin; Self Administration; Time Factors | 2018 |
Fatty acid binding protein deletion prevents stress-induced preference for cocaine and dampens stress-induced corticosterone levels.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Corticosterone; Drug-Seeking Behavior; Extinction, Psychological; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Proteins; Reward; Stress, Psychological | 2018 |
Stress augments the rewarding memory of cocaine via the activation of brainstem-reward circuitry.
Topics: Adrenergic alpha-Antagonists; Adrenergic Neurons; Animals; Brain Stem; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Idazoxan; Male; Memory; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Restraint, Physical; Reward; Stress, Psychological; Tegmentum Mesencephali; Timolol | 2019 |
MHC class I in dopaminergic neurons suppresses relapse to reward seeking.
Topics: Animals; Behavior, Animal; Cocaine; Dopaminergic Neurons; Extinction, Psychological; Glutamates; Histocompatibility Antigens Class I; Mice, Inbred C57BL; Mice, Knockout; Reward; Self Administration; Sucrose; Synaptic Transmission; Ventral Tegmental Area | 2018 |
Toll-like receptor 3 modulates the behavioral effects of cocaine in mice.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression Regulation; Green Fluorescent Proteins; I-kappa B Kinase; Locomotion; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-KappaB Inhibitor alpha; Nucleus Accumbens; Reward; Self Administration; Toll-Like Receptor 3; Transcription Factor RelA; Transduction, Genetic | 2018 |
Environmental enrichment reduces cocaine neurotoxicity during cocaine-conditioned place preference in male rats.
Topics: Animals; Antioxidants; Brain; Catalase; Cocaine; Comet Assay; Conditioning, Classical; DNA Damage; Environment; Male; Neurotoxicity Syndromes; Oxidation-Reduction; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Reward; Superoxide Dismutase | 2018 |
Previous cocaine self-administration disrupts reward expectancy encoding in ventral striatum.
Topics: Animals; Anticipation, Psychological; Choice Behavior; Cocaine; Dopamine Uptake Inhibitors; Male; Random Allocation; Rats; Rats, Long-Evans; Reward; Self Administration; Ventral Striatum | 2018 |
NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward.
Topics: Animals; Brain; Circadian Rhythm; CLOCK Proteins; Cocaine; Conditioning, Operant; Conditioning, Psychological; Male; Mice; Mice, Inbred BALB C; NAD; Neurons; Nucleus Accumbens; Oxidation-Reduction; Reward; Sirtuin 1; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2019 |
Nicotinamide phosphoribosyltransferase regulates cocaine reward through Sirtuin 1.
Topics: Animals; Cocaine; Conditioning, Psychological; Cytokines; Dopamine Uptake Inhibitors; Locomotion; Magnetic Resonance Spectroscopy; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nicotinamide Phosphoribosyltransferase; Reward; Sirtuin 1; Ventral Tegmental Area | 2018 |
A neural network for intermale aggression to establish social hierarchy.
Topics: Aggression; Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Glutamic Acid; Hierarchy, Social; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nerve Net; Neural Conduction; Neurons; Optogenetics; Reward; Ventromedial Hypothalamic Nucleus | 2018 |
Not worth the wait: cocaine alters reward processing in the nucleus accumbens.
Topics: Cocaine; Nucleus Accumbens; Reward; Self Administration; Ventral Striatum | 2018 |
Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain's Reward Circuitry.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Dopamine Uptake Inhibitors; Gene Expression Regulation; Gene Regulatory Networks; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Self Administration; Sequence Analysis, RNA; Transcriptome | 2018 |
(-)-Stepholidine reduces cue-induced reinstatement of cocaine seeking and cocaine self-administration in rats.
Topics: Animals; Berberine; Cocaine; Cues; Dopamine Agonists; Dopamine Antagonists; Extinction, Psychological; Locomotion; Male; Rats; Reinforcement, Psychology; Reward; Self Administration | 2018 |
c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo.
Topics: Animals; Autonomic Nervous System; Cocaine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Reward; Substance Withdrawal Syndrome; Transcriptional Activation; Ventral Tegmental Area | 2018 |
Compulsive sucrose- and cocaine-seeking behaviors in male and female Wistar rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Compulsive Behavior; Dose-Response Relationship, Drug; Estrous Cycle; Female; Male; Punishment; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration; Sucrose | 2018 |
Baseline prepulse inhibition of the startle reflex predicts the sensitivity to the conditioned rewarding effects of cocaine in male and female mice.
Topics: Animals; Cocaine; Conditioning, Classical; Dopamine; Dopamine Uptake Inhibitors; Female; Forecasting; Male; Mice; Nucleus Accumbens; Prepulse Inhibition; Reflex, Startle; Reward | 2018 |
Activation of GABAergic Neurons in the Nucleus Accumbens Mediates the Expression of Cocaine-Associated Memory.
Topics: Animals; Clozapine; Cocaine; Cocaine-Related Disorders; GABAergic Neurons; Humans; Male; Mice; Mice, Transgenic; Nucleus Accumbens; Patch-Clamp Techniques; Reinforcement, Psychology; Reward; Synaptic Potentials | 2018 |
Genetic loss of GluN2B in D1-expressing cell types enhances long-term cocaine reward and potentiation of thalamo-accumbens synapses.
Topics: Animals; Cocaine; Gene Deletion; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reward; Thalamus | 2018 |
Regulators of G-protein signaling 2 and 4 differentially regulate cocaine-induced rewarding effects.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine Uptake Inhibitors; Female; Male; Mice, Knockout; Motor Activity; Reward; RGS Proteins; Sex Factors; Spatial Behavior | 2018 |
Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol.
Topics: Amphetamine; Animals; Cocaine; Designer Drugs; Dopamine; Dopaminergic Neurons; Male; Mice, Inbred C57BL; Reward; Signal Transduction; Ventral Tegmental Area | 2019 |
Contribution of cocaine-related cues to concurrent monetary choice in humans.
Topics: Adult; Attention; Choice Behavior; Cocaine; Cocaine-Related Disorders; Cues; Female; Humans; Male; Middle Aged; Photic Stimulation; Prospective Studies; Reward | 2018 |
Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward.
Topics: Animals; Bariatric Surgery; Behavior, Animal; Bile; Choice Behavior; Cocaine; Dopamine; Gallbladder; Ileum; Male; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nucleus Accumbens; Reward; Signal Transduction | 2018 |
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine.
Topics: Adaptation, Physiological; Animals; Brain; Cocaine; Gene Expression Profiling; Gene Expression Regulation; Gene Transfer Techniques; Interneurons; Locomotion; Male; Mice; Mice, Inbred C57BL; Neurons; Nucleus Accumbens; Optogenetics; Proto-Oncogene Proteins c-jun; Reward; Sequence Analysis, RNA; Somatostatin; Transcription Factors; Transcriptome | 2018 |
Opposing roles of CB
Topics: Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cocaine; Conditioning, Classical; Endocannabinoids; Glycerides; Male; Mice; Motor Activity; Polyunsaturated Alkamides; Protein Binding; Proto-Oncogene Proteins c-fos; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reward | 2019 |
Repeated cocaine exposure dysregulates cognitive control over cue-evoked reward-seeking behavior during Pavlovian-to-instrumental transfer.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Male; Rats; Rats, Long-Evans; Reward; Transfer, Psychology | 2018 |
Close or far? Affect explains conflicting findings on motivated distance perception to rewards.
Topics: Adolescent; Affect; Candy; Distance Perception; Eating; Female; Humans; Male; Motivation; Reward; Young Adult | 2018 |
A Neuronal Ensemble in the Rostral Agranular Insula Tracks Cocaine-Induced Devaluation of Natural Reward and Predicts Cocaine Seeking.
Topics: Affect; Animals; Cerebral Cortex; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Lithium Chloride; Male; Neurons; Quinine; Rats, Sprague-Dawley; Reward; Saccharin; Taste; Taste Perception | 2018 |
On the positive association between candy and fruit gum consumption and hyperactivity in children and adolescents with ADHD.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Candy; Child; Diet; Dietary Carbohydrates; Energy Metabolism; Fruit; Humans; Reward; Surveys and Questionnaires | 2019 |
The histone demethylase KDM6B in the medial prefrontal cortex epigenetically regulates cocaine reward memory.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Psychological; Enzyme Inhibitors; Extinction, Psychological; Jumonji Domain-Containing Histone Demethylases; Male; Memory; Memory Consolidation; Mice; Prefrontal Cortex; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome | 2018 |
Chemokine CXCL1 is responsible for cocaine-induced reward in mice.
Topics: Animals; Benzazepines; Benzimidazoles; Chemokine CCL2; Chemokine CXCL1; Cocaine; Cocaine-Related Disorders; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Phenylurea Compounds; Prefrontal Cortex; Reward; RNA, Messenger | 2018 |
Impairments in reversal learning following short access to cocaine self-administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Rats; Rats, Sprague-Dawley; Reversal Learning; Reward; Self Administration; Sucrose | 2018 |
Social stress during adolescence activates long-term microglia inflammation insult in reward processing nuclei.
Topics: Animals; Astrocytes; Brain; Cell Count; Cocaine; Conditioning, Psychological; Inflammation; Male; Mice; Microglia; Neurons; Reward; Stress, Psychological | 2018 |
Reward and executive control network resting-state functional connectivity is associated with impulsivity during reward-based decision making for cocaine users.
Topics: Adult; Brain; Brain Mapping; Cocaine; Cocaine-Related Disorders; Decision Making; Executive Function; Female; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Male; Nerve Net; Reward | 2019 |
Intermittent intake of rapid cocaine injections promotes the risk of relapse and increases mesocorticolimbic BDNF levels during abstinence.
Topics: Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Craving; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Nucleus Accumbens; Prefrontal Cortex; Rats; Reward; Self Administration; Time Factors; Ventral Tegmental Area | 2019 |
Cocaine and cocaine expectancy increase growth hormone, ghrelin, GLP-1, IGF-1, adiponectin, and corticosterone while decreasing leptin, insulin, GIP, and prolactin.
Topics: Adiponectin; Animals; Cocaine; Cocaine-Related Disorders; Corticosterone; Disease Models, Animal; Drug Substitution; Gastric Inhibitory Polypeptide; Ghrelin; Glucagon-Like Peptide 1; Growth Hormone; Injections, Intravenous; Insulin; Leptin; Prolactin; Rats; Reward; Saline Solution; Self Administration; Signal Transduction | 2019 |
GABA
Topics: Allosteric Regulation; Animals; Baclofen; Behavior, Animal; Benzofurans; Central Nervous System Depressants; CHO Cells; Cocaine; Cricetulus; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Ethanol; GABA Modulators; GABA-B Receptor Agonists; Humans; Mice; Neuronal Plasticity; Quinazolinones; Rats; Receptors, GABA-B; Receptors, Glutamate; Reward; Self Administration; Ventral Tegmental Area | 2019 |
Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats.
Topics: Adenosine A2 Receptor Agonists; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Ligands; Male; Microinjections; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reward; Self Administration | 2018 |
Oxytocin prevents the increase of cocaine-related responses produced by social defeat.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Cocaine; Conditioning, Classical; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Hippocampus; Male; Mice; Oxytocin; Prefrontal Cortex; Reinforcement, Psychology; Reward; Self Administration; Stress, Psychological | 2019 |
Killing the Buζζ: accumbal PKMζ blunts cocaine seeking and reward.
Topics: Cocaine; Dopamine Uptake Inhibitors; Nucleus Accumbens; Reward | 2019 |
Persistence of Drug Memories: Melting Transcriptomes.
Topics: Brain; Cocaine; Memory; Reward; Transcriptome | 2018 |
Increased cocaine reward in offspring of females exposed to morphine during adolescence.
Topics: Age Factors; Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Female; Male; Morphine; Nucleus Accumbens; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Self Administration; Sex Characteristics | 2019 |
A neuronal population code for resemblance between drug and nondrug reward outcomes in the orbitofrontal cortex.
Topics: Animals; Choice Behavior; Cocaine; Dopamine Uptake Inhibitors; Heroin; Male; Narcotics; Neurons; Prefrontal Cortex; Rats; Rats, Wistar; Reward | 2019 |
Indomethacin blocks the increased conditioned rewarding effects of cocaine induced by repeated social defeat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dominance-Subordination; Exploratory Behavior; Indomethacin; Interleukin-6; Mice; Psychotropic Drugs; Random Allocation; Reward; Stress, Psychological | 2018 |
Role of N-methyl-D-aspartate receptors in the long-term effects of repeated social defeat stress on the rewarding and psychomotor properties of cocaine in mice.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Male; Memantine; Mice; Mice, Inbred Strains; Psychological Distance; Receptors, N-Methyl-D-Aspartate; Reward; Social Behavior; Stress, Psychological | 2019 |
Operant Costs Modulate Dopamine Release to Self-Administered Cocaine.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Food; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reward; Self Administration | 2019 |
Prior Exposure to Salient Win-Paired Cues in a Rat Gambling Task Increases Sensitivity to Cocaine Self-Administration and Suppresses Dopamine Efflux in Nucleus Accumbens: Support for the Reward Deficiency Hypothesis of Addiction.
Topics: Acoustic Stimulation; Animals; Behavior, Addictive; Cocaine; Cues; Dopamine; Drug-Seeking Behavior; Gambling; Locomotion; Male; Nucleus Accumbens; Photic Stimulation; Rats, Long-Evans; Reward | 2019 |
Sigma-1 receptor antagonist PD144418 suppresses food reinforced operant responding in rats.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Eating; Isoxazoles; Motivation; Pyridines; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement, Psychology; Reward; Sigma-1 Receptor | 2019 |
Expectancy-Related Changes in Dopaminergic Error Signals Are Impaired by Cocaine Self-Administration.
Topics: Action Potentials; Analysis of Variance; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Rats; Reward; Self Administration; Ventral Tegmental Area | 2019 |
The Associations between Body Mass Index of Seven- and Eight-Year-Old Children, Dietary Behaviour and Nutrition-Related Parenting Practices.
Topics: Anthropometry; Body Mass Index; Candy; Child; Child Nutritional Physiological Phenomena; Dairy Products; Diet; Diet, Healthy; Dietary Proteins; Fast Foods; Feeding Behavior; Female; Humans; Linear Models; Lithuania; Male; Meat Products; Nutritive Value; Parenting; Pediatric Obesity; Punishment; Reward; Surveys and Questionnaires; Vegetable Products | 2019 |
Effects of chronic cocaine exposure on the circadian rhythmic expression of the clock genes in reward-related brain areas in rats.
Topics: Animals; Brain; Circadian Rhythm; Cocaine; Gene Expression Regulation; Hippocampus; Male; Nuclear Proteins; Nucleus Accumbens; Period Circadian Proteins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reward; Suprachiasmatic Nucleus; Transcription Factors; Ventral Tegmental Area | 2019 |
Ghrelin Receptor Influence on Cocaine Reward is Not Directly Dependent on Peripheral Acyl-Ghrelin.
Topics: Animals; Appetite; Blood-Brain Barrier; Central Nervous System; Cocaine; Craving; Energy Metabolism; Ghrelin; Humans; Male; Mice; Receptors, Ghrelin; Reward; Signal Transduction; Weight Gain | 2019 |
Inflexible habitual decision-making during choice between cocaine and a nondrug alternative.
Topics: Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Operant; Cues; Decision Making; Habits; Male; Motivation; Rats; Rats, Wistar; Reward; Self Administration | 2019 |
Effects of ketamine treatment on cocaine-induced reinstatement and disruption of functional connectivity in unanesthetized rhesus monkeys.
Topics: Anesthetics, Dissociative; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Extinction, Psychological; Female; Frontal Lobe; Ketamine; Macaca mulatta; Magnetic Resonance Imaging; Nerve Net; Reward; Self Administration; Treatment Outcome | 2019 |
Lack of correlation between the activity of the mesolimbic dopaminergic system and the rewarding properties of pregabalin in mouse.
Topics: Analgesics; Animals; Cocaine; Conditioning, Classical; Dopamine; Dopaminergic Neurons; Male; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; Nucleus Accumbens; Pregabalin; Reward; Ventral Tegmental Area | 2019 |
Epigenetic effects of paternal cocaine on reward stimulus behavior and accumbens gene expression in mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cytokines; Disease Models, Animal; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Fathers; Female; Gene Expression Regulation; Inheritance Patterns; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Reward; Sequence Analysis, RNA; Sex Characteristics | 2019 |
Withdrawal from escalated cocaine self-administration impairs reversal learning by disrupting the effects of negative feedback on reward exploitation: a behavioral and computational analysis.
Topics: Animals; Cocaine; Conditioning, Operant; Drug-Seeking Behavior; Male; Models, Neurological; Prefrontal Cortex; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin, 5-HT2; Reversal Learning; Reward; Ventral Striatum | 2019 |
Cocaine-induced behavioral sensitization is greater in adolescent than in adult mice and heightens cocaine-induced conditioned place preference in adolescents.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Drug Evaluation, Preclinical; Locomotion; Male; Mice; Reward; Saline Solution | 2019 |
Vertical sleeve gastrectomy in adolescents reduces the appetitive reward value of a sweet and fatty reinforcer in a progressive ratio task.
Topics: Adolescent; Appetite; Candy; Dietary Fats; Energy Intake; Female; Food Preferences; Gastrectomy; Humans; Male; Pediatric Obesity; Prospective Studies; Reinforcement, Psychology; Reward; Weight Loss | 2019 |
Neuronal HMGB1 in nucleus accumbens regulates cocaine reward memory.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; HMGB1 Protein; Male; Memory; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2020 |
Gray and white matter alterations in cocaine addiction: Clinical and methodological aspects.
Topics: Cocaine; Cocaine-Related Disorders; Humans; Motivation; Reward; White Matter | 2020 |
Investigating the computational underpinnings of addiction.
Topics: Behavior, Addictive; Cocaine; Reversal Learning; Reward; Self Administration | 2019 |
[Analyses of cocaine rewarding memories by AAV vector-induced introduction of DREADD system].
Topics: Animals; Cocaine; Dependovirus; GABAergic Neurons; Genetic Vectors; Memory; Mice; Nucleus Accumbens; Prefrontal Cortex; Pyramidal Cells; Reward | 2019 |
Changes in the glutamate biomarker expression in rats vulnerable or resistant to the rewarding effects of cocaine and their reversal by ceftriaxone.
Topics: Amino Acid Transport Systems, Acidic; Animals; Biomarkers, Pharmacological; Brain; Ceftriaxone; Cocaine; Cocaine-Related Disorders; Drug-Seeking Behavior; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glutamic Acid; Male; NF-E2-Related Factor 2; NF-kappa B; Nucleus Accumbens; Rats; Rats, Wistar; Reward; Self Administration | 2019 |
The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice.
Topics: Acetylation; Animals; Benzamides; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Diphenylamine; Gene Knockdown Techniques; Genetic Vectors; Histones; Lentivirus; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Organ Specificity; Phosphorylation; Protein Processing, Post-Translational; ras Guanine Nucleotide Exchange Factors; ras-GRF1; Reward; RNA, Small Interfering; Self Administration | 2019 |
Role of the orbitofrontal cortex and the dorsal striatum in incentive motivation for cocaine.
Topics: Animals; Baclofen; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Drug-Seeking Behavior; Male; Motivation; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Self Administration | 2019 |
Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal.
Topics: Animals; Cocaine; Excitatory Postsynaptic Potentials; Male; Mice, Transgenic; Morphine; Neuronal Plasticity; Neurons; Nucleus Accumbens; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2019 |
Loss of CELF6 RNA binding protein impairs cocaine conditioned place preference and contextual fear conditioning.
Topics: Animals; CELF Proteins; Cocaine; Conditioning, Classical; Dopaminergic Neurons; Exploratory Behavior; Fear; Female; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mutation; Reward; RNA, Messenger | 2019 |
Strain differences in maternal neuroendocrine and behavioral responses to stress and the relation to offspring cocaine responsiveness.
Topics: Animals; Behavior, Animal; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Female; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Restraint, Physical; Reward; Species Specificity; Stress, Psychological | 2019 |
Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals.
Topics: Acoustic Stimulation; Animals; Avoidance Learning; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Enzyme Activation; Gerbillinae; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Reward | 2019 |
Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits.
Topics: Agouti-Related Protein; Amphetamine; Animals; Central Nervous System Depressants; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Ethanol; Feeding Behavior; Hypothalamus; Mice; Neural Pathways; Neurons; Nicotine; Nicotinic Agonists; Pro-Opiomelanocortin; Reward; Vagotomy; Vagus Nerve | 2019 |
Role of mesolimbic ghrelin in the acquisition of cocaine reward.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Ghrelin; Glycine; Injections, Intraventricular; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Triazoles; Ventral Tegmental Area | 2019 |
Opposite environmental gating of the experienced utility ('liking') and decision utility ('wanting') of heroin versus cocaine in animals and humans: implications for computational neuroscience.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cocaine; Computer Simulation; Decision Making; Dopamine Uptake Inhibitors; Emotions; Female; Heroin; Humans; Male; Models, Psychological; Motivation; Neurosciences; Rats; Rats, Sprague-Dawley; Reward | 2019 |
Activation of GSK3β induced by recall of cocaine reward memories is dependent on GluN2A/B NMDA receptor signaling.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Glycogen Synthase Kinase 3 beta; Male; Memory Consolidation; Mental Recall; Mice; Protein Phosphatase 1; Receptors, N-Methyl-D-Aspartate; Reward; Signal Transduction | 2019 |
Clonidine, an α2 adrenergic receptor agonist, disrupts reconsolidation of a cocaine-paired environmental memory.
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Cues; Male; Memory; Memory Consolidation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reward | 2019 |
Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT
Topics: Animals; Anticonvulsants; Cannabidiol; Cocaine; Dopamine; Dose-Response Relationship, Drug; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB2; Receptor, Serotonin, 5-HT1A; Reinforcement Schedule; Reward; Self Administration; TRPV Cation Channels | 2020 |
Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids.
Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Central Nervous System Stimulants; Cocaine; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2020 |
Social defeat-induced increase in the conditioned rewarding effects of cocaine: Role of CX3CL1.
Topics: Animals; Chemokine CX3CL1; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reward; Social Defeat | 2020 |
Delta-9-THC exposure during zebra finch sensorimotor vocal learning increases cocaine reinforcement in adulthood.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Dronabinol; Female; Finches; Learning; Male; Nicotine; Reinforcement, Psychology; Reward; Sensorimotor Cortex; Sex Factors; Vocalization, Animal | 2019 |
Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Estrous Cycle; Female; Granulocyte Colony-Stimulating Factor; Mice; Nucleus Accumbens; Reward | 2019 |
The presence of a social stimulus reduces cocaine-seeking in a place preference conditioning paradigm.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Male; Mice; Mice, Inbred C57BL; Reward; Social Behavior; Social Isolation | 2019 |
Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol.
Topics: Animals; Brain; Cocaine; Conditioning, Classical; Dopamine; Dopamine Uptake Inhibitors; Estradiol; Estrogens; Female; Mice, Inbred C57BL; Ovariectomy; Proteome; Proteomics; Reward; Ventral Tegmental Area | 2019 |
Within-animal comparisons of novelty and cocaine neuronal ensemble overlap in the nucleus accumbens and prefrontal cortex.
Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Exploratory Behavior; Female; Male; Mice; Mice, Transgenic; Nucleus Accumbens; Prefrontal Cortex; Reward; Sex Characteristics; Stress, Psychological | 2020 |
Ad libitum high fat diet consumption during adolescence and adulthood fails to impact the affective properties of cocaine in male Sprague-Dawley rats.
Topics: Administration, Intravenous; Animals; Cocaine; Conditioning, Psychological; Diet, High-Fat; Male; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Taste | 2020 |
Distinct relationships between risky decision making and cocaine self-administration under short- and long-access conditions.
Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Decision Making; Female; Male; Punishment; Rats; Rats, Long-Evans; Reward; Risk; Risk-Taking; Self Administration; Sex Characteristics | 2020 |
Conditioned taste avoidance induced by the combination of heroin and cocaine: Implications for the use of speedball.
Topics: Animals; Aversive Agents; Avoidance Learning; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Heroin; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Self Administration; Taste | 2019 |
Reward and immune responses in adolescent females following experimental traumatic brain injury.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Brain Injuries, Traumatic; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Estradiol; Female; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotection; Progesterone; Reward; Sex Characteristics | 2020 |
Prenatal and postnatal alcohol exposure increases vulnerability to cocaine addiction in adult mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Pregnancy; Reward | 2020 |
Cocaine experience abolishes the motivation suppressing effect of CRF in the ventral midbrain.
Topics: Animals; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine; Drug-Seeking Behavior; Male; Motivation; Nucleus Accumbens; Rats; Receptors, Corticotropin-Releasing Hormone; Reward; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2021 |
Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.
Topics: alpha-Synuclein; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Disease Susceptibility; Dopaminergic Neurons; Extracellular Space; Immunohistochemistry; Male; Mesencephalon; Mice; Mice, Knockout; Models, Biological; Motivation; Motor Activity; Reward; Signal Transduction | 2019 |
Prior cocaine self-administration impairs attention signals in anterior cingulate cortex.
Topics: Animals; Attention; Behavior, Animal; Cocaine; Decision Making; Dopamine Uptake Inhibitors; Female; Gyrus Cinguli; Male; Neurons; Rats, Long-Evans; Reward | 2020 |
The potent psychomotor, rewarding and reinforcing properties of 3-fluoromethamphetamine in rodents.
Topics: Animals; Cocaine; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration | 2020 |
Phosphorylation of Npas4 by MAPK Regulates Reward-Related Gene Expression and Behaviors.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Brain-Derived Neurotrophic Factor; Cell Line; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Female; Gene Expression; Male; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Proteomics; Receptors, Dopamine D1; Reward; Signal Transduction; Transcription, Genetic | 2019 |
The sigma receptor ligand N-phenylpropyl-N'-(4-methoxyphenethyl)3piperazine (YZ-067) enhances the cocaine conditioned-rewarding properties while inhibiting the development of sensitization of cocaine in mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Piperazines; Protein Binding; Receptors, sigma; Reward | 2020 |
Cocaine Dysregulates Dynorphin Modulation of Inhibitory Neurotransmission in the Ventral Pallidum in a Cell-Type-Specific Manner.
Topics: Animals; Basal Forebrain; Cocaine; Drug-Seeking Behavior; Dynorphins; Female; Male; Mice; Mice, Inbred C57BL; Neurons; Reward; Substance Withdrawal Syndrome; Synaptic Transmission | 2020 |
Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Collaborative Cross Mice; Corpus Striatum; Dopamine Uptake Inhibitors; Female; Hypothalamo-Hypophyseal System; Locomotion; Male; Mice; Pituitary-Adrenal System; Reinforcement, Psychology; Reward; Self Administration; Species Specificity | 2020 |
Alcohol inhibits morphine/cocaine reward memory acquisition and reconsolidation in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Memory; Morphine; Rats; Rats, Sprague-Dawley; Reward | 2020 |
Microglial activation increases cocaine self-administration following adolescent nicotine exposure.
Topics: Aminopyridines; Animals; Chemokine CX3CL1; Cocaine; Disease Models, Animal; Drug-Seeking Behavior; Electronic Nicotine Delivery Systems; Female; Gene Expression Regulation; Male; Microglia; Minocycline; Nicotine; Phenotype; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration; Synaptophysin | 2020 |
History of withdrawal modulates drug- and food-cue reactivity in cocaine dependent participants.
Topics: Adult; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Female; Food; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Reward; Substance Withdrawal Syndrome; Young Adult | 2020 |
Social interaction reward in rats has anti-stress effects.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Male; Nucleus Accumbens; Rats; Receptors, Corticotropin-Releasing Hormone; Reward; Social Interaction; Stress, Psychological | 2021 |
Acute restraint stress augments the rewarding memory of cocaine through activation of α
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Cocaine; Dopamine Uptake Inhibitors; Female; Male; Memory; Mice; Microinjections; Prefrontal Cortex; Receptors, Adrenergic, alpha-1; Restraint, Physical; Reward; Stress, Psychological | 2020 |
Behavioral and neuroimmune characterization of resilience to social stress: Rewarding effects of cocaine.
Topics: Animals; Cocaine; Disease Models, Animal; Humans; Male; Mice; Reward; Stress, Psychological | 2021 |
Enduring effects of adolescent ketamine exposure on cocaine- and sucrose-induced reward in male and female C57BL/6 mice.
Topics: Animals; Cocaine; Female; Ketamine; Male; Mice; Mice, Inbred C57BL; Reward; Stress, Psychological; Sucrose | 2020 |
Cocaine self-administration differentially activates microglia in the mouse brain.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Male; Mice, Inbred C57BL; Microglia; Neostriatum; Reward; Self Administration; Up-Regulation | 2020 |
Maternal immune activation is associated with a lower number of dopamine receptor 3-expressing granulocytes with no alterations in cocaine reward, resistance to extinction or cue-induced reinstatement.
Topics: Animals; Biomarkers; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Extinction, Psychological; Female; Granulocytes; Leukocyte Count; Lipopolysaccharides; Male; Pregnancy; Prepulse Inhibition; Rats; Rats, Inbred Lew; Receptor, Cannabinoid, CB2; Receptors, Dopamine D3; Reward; Schizophrenia; Self Administration; T-Lymphocytes | 2020 |
Endogenous oxytocin is essential for the buffering effects of pair housing against the increase in cocaine reward induced by social stress.
Topics: Animals; Cocaine; Housing; Male; Mice; Oxytocin; Reward; Social Behavior; Stress, Psychological | 2020 |
Reorganization of theta phase-locking in the orbitofrontal cortex drives cocaine choice under the influence.
Topics: Animals; Choice Behavior; Cocaine; Electrophysiological Phenomena; Male; Neural Pathways; Prefrontal Cortex; Rats; Reward; Theta Rhythm | 2020 |
Modulation of cocaine-related behaviors by low doses of the potent KOR agonist nalfurafine in male C57BL6 mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Behavior, Addictive; Cocaine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphinans; Receptors, Opioid, kappa; Reward; Self Administration; Signal Transduction; Spiro Compounds | 2020 |
Maternal Diet Influences the Reinstatement of Cocaine-Seeking Behavior and the Expression of Melanocortin-4 Receptors in Female Offspring of Rats.
Topics: Animals; Behavior, Animal; Cocaine; Diet; Diet, High-Fat; Drug-Seeking Behavior; Female; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptor, Melanocortin, Type 4; Reward | 2020 |
The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain.
Topics: Animals; Brain; Central Amygdaloid Nucleus; Channelrhodopsins; Cocaine; Cues; Female; Learning; Male; Motivation; Optogenetics; Pain; Rats, Sprague-Dawley; Reward; Sucrose | 2020 |
Cocaine reward and memory after chemogenetic inhibition of distinct serotonin neuron subtypes in mice.
Topics: Animals; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reward; Serotonergic Neurons | 2020 |
KVA-D-88, a Novel Preferable Phosphodiesterase 4B Inhibitor, Decreases Cocaine-Mediated Reward Properties
Topics: Animals; Cocaine; Cyclic Nucleotide Phosphodiesterases, Type 4; Mice; Phosphodiesterase 4 Inhibitors; Reward; Rolipram | 2020 |
The impact of GABA
Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Depression; Disease Models, Animal; Drug-Seeking Behavior; GABA-B Receptor Agonists; Male; Organophosphorus Compounds; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Reward | 2020 |
Environmental enrichment during forced abstinence from cocaine self-administration opposes gene network expression changes associated with the incubation effect.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug-Seeking Behavior; Environment; Gene Expression Regulation; Gene Regulatory Networks; Male; Neurons; Rats; Rats, Sprague-Dawley; Reelin Protein; Reward; RNA-Seq; Self Administration; Signal Transduction; Synapses | 2020 |
Parametric investigation of social place preference in adolescent mice.
Topics: Aging; Animals; Cocaine; Conditioning, Classical; Female; Male; Mice; Mice, Inbred C57BL; Reward; Sex Characteristics; Social Behavior; Social Isolation | 2020 |
Zeta Inhibitory Peptide attenuates learning and memory by inducing NO-mediated downregulation of AMPA receptors.
Topics: Animals; Cell-Penetrating Peptides; Cocaine; Conditioning, Psychological; Down-Regulation; Endocytosis; Excitatory Postsynaptic Potentials; HEK293 Cells; Humans; Lipopeptides; Long-Term Potentiation; Male; Memory, Long-Term; Mice; Models, Animal; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nucleus Accumbens; Phosphorylation; Primary Cell Culture; Protein Kinase C; Rats; Receptors, AMPA; Reward; Stereotaxic Techniques | 2020 |
Claustral Neurons Projecting to Frontal Cortex Mediate Contextual Association of Reward.
Topics: Animals; Basal Ganglia; Claustrum; Cocaine; Dopamine Uptake Inhibitors; Frontal Lobe; Male; Mice; Mice, Inbred C57BL; Neurons; Receptors, Dopamine D1; Reward | 2020 |
Role of Long Noncoding RNA Gas5 in Cocaine Action.
Topics: Animals; Cocaine; Gene Expression Regulation; Male; Mice; Nucleus Accumbens; Reward; RNA, Long Noncoding | 2020 |
Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction.
Topics: Animals; Behavior, Addictive; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Rats; Reward; Self Administration | 2021 |
(±)VK4-40, a novel dopamine D
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Mice; Pharmaceutical Preparations; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reward; Rodentia; Self Administration | 2020 |
Cue-elicited functional connectivity of the periaqueductal gray and tonic cocaine craving.
Topics: Adult; Anxiety; Cocaine; Cocaine-Related Disorders; Craving; Cues; Female; Humans; Magnetic Resonance Imaging; Male; Periaqueductal Gray; Prefrontal Cortex; Reward; Substance Withdrawal Syndrome; Young Adult | 2020 |
Sugar now or cocaine later?
Topics: Behavior, Addictive; Cocaine; Dopamine; Reward; Sugars | 2021 |
Cross-generational THC Exposure Weakly Attenuates Cocaine's Rewarding Effects in Adult Male Offspring.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Dronabinol; Female; Male; Rats; Reward; Self Administration | 2020 |
Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation.
Topics: Administration, Oral; Animals; Circadian Clocks; Cocaine; Cocaine-Related Disorders; Dopamine; Injections, Intraperitoneal; Locomotion; Male; Mice; Mice, Knockout; Neurons; Nucleus Accumbens; Pioglitazone; PPAR gamma; Receptors, Dopamine D2; Reward; Signal Transduction | 2020 |
Behavioral effects of SGK1 knockout in VTA and dopamine neurons.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Female; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Serine-Threonine Kinases; Reward; Signal Transduction; Ventral Tegmental Area | 2020 |
Housing conditions during self-administration determine motivation for cocaine in mice following chronic social defeat stress.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Cues; Extinction, Psychological; Housing, Animal; Male; Mice; Mice, Inbred C57BL; Motivation; Rats; Reward; Self Administration; Social Behavior; Social Defeat; Social Isolation; Stress, Psychological | 2021 |
Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core.
Topics: Animals; Cocaine; Cues; Drug-Seeking Behavior; Extinction, Psychological; Mice; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Sucrose | 2020 |
Exercise craving potentiates excitatory inputs to ventral tegmental area dopaminergic neurons.
Topics: Amphetamine; Animals; Cocaine; Craving; Cues; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dronabinol; Excitatory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Reward; Synapses; Ventral Tegmental Area | 2021 |
Cannabidiol (CBD) reduces cocaine-environment memory in mice.
Topics: Animals; Cannabidiol; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Extinction, Psychological; Locomotion; Male; Memory; Mice; Mice, Inbred C57BL; Reward | 2020 |
Critical role of TLR4 in uncovering the increased rewarding effects of cocaine and ethanol induced by social defeat in male mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine Uptake Inhibitors; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reward; Self Administration; Social Defeat; Toll-Like Receptor 4 | 2021 |
There's no place like home? Return to the home cage triggers dopamine release in the mouse nucleus accumbens.
Topics: Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Housing, Animal; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Nucleus Accumbens; Photometry; Reward | 2021 |
Activation of the amylin pathway modulates cocaine-induced activation of the mesolimbic dopamine system in male mice.
Topics: Animals; Brain; Calcitonin; Cocaine; Dopamine; Islet Amyloid Polypeptide; Locomotion; Male; Mice; Neuropeptides; Nucleus Accumbens; Receptors, Dopamine; Reward; Signal Transduction; Ventral Tegmental Area | 2021 |
Entopeduncular Nucleus Projections to the Lateral Habenula Contribute to Cocaine Avoidance.
Topics: Animals; Avoidance Learning; Cocaine; Cocaine-Related Disorders; Electrophysiological Phenomena; Entopeduncular Nucleus; Habenula; Male; Neural Pathways; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reward; Ventral Tegmental Area | 2021 |
Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making.
Topics: Animals; Choice Behavior; Cocaine; Cocaine-Related Disorders; Decision Making; Interneurons; Male; Neostriatum; Neurons; Odorants; Psychomotor Performance; Rats; Rats, Long-Evans; Reaction Time; Reward; Self Administration; Sucrose | 2021 |
Blunted prefrontal signature of proactive inhibitory control in cocaine use disorder.
Topics: Adult; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Cues; Executive Function; Female; Humans; Impulsive Behavior; Inhibition, Psychological; Magnetic Resonance Imaging; Male; Motivation; Reward; Substance-Related Disorders | 2021 |
Role of 5-HT
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Infusions, Intraventricular; Male; Memory; Mice; Mice, Inbred C57BL; Piperazines; Prefrontal Cortex; Pyridines; Receptor, Serotonin, 5-HT1A; Restraint, Physical; Reward; Serotonergic Neurons; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Stress, Psychological | 2021 |
Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Versus Social Interaction Reward.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Social Interaction | 2020 |
Distinct populations of cortical pyramidal neurons mediate drug reward and aversion.
Topics: Animals; Cerebral Cortex; Cocaine; Electrophysiological Phenomena; Male; Pharmaceutical Preparations; Pyramidal Cells; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Reward | 2021 |
Lever-press duration as a measure of frustration in sucrose and drug reinforcement.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Craving; Frustration; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Self Administration; Sucrose | 2021 |
Exogenous SO
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Humans; Memory Consolidation; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward; Sulfites; Sulfur Dioxide; Time Factors | 2021 |
Repeated exposure to cocaine during adolescence enhances the rewarding threshold for cocaine-conditioned place preference in adulthood.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Female; Male; Motivation; Rats; Receptors, AMPA; Reward; Self Administration | 2021 |
An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system.
Topics: Animals; Autophagy-Related Proteins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Reward | 2021 |
Reducing alcohol and/or cocaine-induced reward and toxicity via an epidermal stem cell-based gene delivery platform.
Topics: Animals; Butyrylcholinesterase; Cocaine; Cocaine-Related Disorders; Mice; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Stem Cells | 2021 |
GABAergic projections to the ventral tegmental area govern cocaine-conditioned reward.
Topics: Animals; Cocaine; Conditioning, Psychological; Dopamine; Dopaminergic Neurons; GABAergic Neurons; gamma-Aminobutyric Acid; Nucleus Accumbens; Optogenetics; Rats; Reward; Ventral Tegmental Area | 2021 |
Past, present and future of cocaine- and amphetamine-regulated transcript peptide.
Topics: Cocaine; Feeding Behavior; Nerve Tissue Proteins; Neuropeptides; Reward | 2021 |
A limited and intermittent access to a high-fat diet modulates the effects of cocaine-induced reinstatement in the conditioned place preference in male and female mice.
Topics: Animals; Cocaine; Conditioning, Classical; Craving; Diet, High-Fat; Dopamine Uptake Inhibitors; Extinction, Psychological; Female; Male; Mice; Reward | 2021 |
Hippocampal mu opioid receptors are modulated following cocaine self-administration in rat.
Topics: Animals; Cocaine; Hippocampus; Rats; Receptors, Opioid, mu; Reward; Self Administration | 2021 |
Prior Cocaine Exposure Increases Firing to Immediate Reward While Attenuating Cue and Context Signals Related to Reward Value in the Insula.
Topics: Animals; Cerebral Cortex; Choice Behavior; Cocaine; Cues; Female; Male; Rats; Rats, Long-Evans; Reward | 2021 |
Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain's Reward Circuitry.
Topics: Animals; Brain; Cocaine; Female; Male; Mice; Nucleus Accumbens; Reward; Transcriptome | 2022 |
Sign- and goal-tracking score does not correlate with addiction-like behavior following prolonged cocaine self-administration.
Topics: Animals; Attention; Behavior, Addictive; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Goals; Male; Motivation; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 2021 |
Acupuncture reduces cocaine psychomotor responses by activating the rostromedial tegmental nucleus.
Topics: Acupuncture Therapy; Animals; Cocaine; GABAergic Neurons; Male; Nucleus Accumbens; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reward; Tegmentum Mesencephali; Ventral Tegmental Area | 2021 |
Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking.
Topics: Animals; Basal Forebrain; Cocaine; Dopamine; Drug-Seeking Behavior; Female; Habenula; Male; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Nucleus Accumbens; Receptors, Dopamine D3; Reward; Ventral Tegmental Area | 2021 |
Cocaine-induced increases in motivation require 2-arachidonoylglycerol mobilization and CB1 receptor activation in the ventral tegmental area.
Topics: Animals; Arachidonic Acids; Cocaine; Conditioning, Operant; Endocannabinoids; Female; Glycerides; Male; Motivation; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Administration; Ventral Tegmental Area | 2021 |
Reinforcer pathology in cocaine use disorder: Temporal window determines cocaine valuation.
Topics: Behavior, Addictive; Cocaine; Delay Discounting; Humans; Reward; Substance-Related Disorders | 2021 |
DRD3-dependent plasticity within the VP drives subcircuit activity critical for cocaine seeking.
Topics: Basal Forebrain; Cocaine; Drug-Seeking Behavior; Neurons; Reward | 2021 |
Acupuncture Modulates Intracranial Self-Stimulation of the Medial Forebrain Bundle in Rats.
Topics: Acupuncture Therapy; Anesthetics, Local; Animals; Cocaine; Electric Stimulation; Male; Medial Forebrain Bundle; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation | 2021 |
Adolescent cannabinoid exposure modulates the vulnerability to cocaine-induced conditioned place preference and DNMT3a expression in the prefrontal cortex in Swiss mice.
Topics: Animals; Cannabinoids; Cocaine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Mice; Prefrontal Cortex; Reward | 2021 |
Decreased kynurenine pathway potentiate resilience to social defeat effect on cocaine reward.
Topics: Animals; Cerebellum; Cocaine; Conditioning, Operant; Environment; Indomethacin; Kynurenine; Male; Mice; Mice, Inbred C57BL; Oxytocin; Resilience, Psychological; Reward; Signal Transduction; Social Defeat; Tryptophan | 2021 |
The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward.
Topics: Animals; Cocaine; Conditioning, Operant; Female; Male; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration | 2021 |
Individual differences in addiction-like behaviors and choice between cocaine versus food in Heterogeneous Stock rats.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Individuality; Rats; Reward; Self Administration | 2021 |
When the front fails, the rear wins. Cerebellar correlates of prefrontal dysfunction in cocaine-induced memory in male rats.
Topics: Animals; Cerebellum; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Interneurons; Lidocaine; Male; Nerve Net; Prefrontal Cortex; Rats; Reward | 2022 |
Chromatin-mediated alternative splicing regulates cocaine-reward behavior.
Topics: Alternative Splicing; Animals; Behavior, Addictive; Chromatin; Cocaine; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Female; Male; Mice; Mice, Inbred C57BL; Reward; Self Administration | 2021 |
Gene splicing SETs the scene for cocaine addiction.
Topics: Cocaine; Cocaine-Related Disorders; Humans; Protein Processing, Post-Translational; Reward | 2021 |
Choosing between cocaine and sucrose under the influence: testing the effect of cocaine tolerance.
Topics: Animals; Cocaine; Rats; Reward; Self Administration; Sucrose; Taste | 2022 |
The association between risky decision making and cocaine conditioned place preference is moderated by sex.
Topics: Animals; Cocaine; Conditioning, Classical; Decision Making; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Reward | 2021 |
Distinct Role of Dopamine in the PFC and NAc During Exposure to Cocaine-Associated Cues.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Conditioning, Classical; Cues; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Mice; Nucleus Accumbens; Prefrontal Cortex; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Reward | 2021 |
Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse.
Topics: Adolescent; Adult; Brain; Cocaine; Humans; Reward; Social Defeat; Stress, Psychological | 2022 |
Extinction of Cocaine Memory Depends on a Feed-Forward Inhibition Circuit Within the Medial Prefrontal Cortex.
Topics: Animals; Cocaine; Extinction, Psychological; Mice; Parvalbumins; Prefrontal Cortex; Reward | 2022 |
Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation.
Topics: Animals; Binding Sites; Cocaine; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Homeostasis; Male; Mice; Motivation; PDZ Domains; Protein Binding; Reward; Self Administration | 2021 |
Effects of neonatal dopaminergic lesion on oral cocaine self-administration in rats: Higher female vulnerability to cocaine consumption.
Topics: Adrenergic Agents; Animals; Animals, Newborn; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Female; Locomotion; Male; Oxidopamine; Prefrontal Cortex; Rats; Receptors, GABA; Reward; Self Administration; Sex Factors | 2022 |
Activation of mesocorticolimbic dopamine projections initiates cue-induced reinstatement of reward seeking in mice.
Topics: Animals; Cocaine; Cues; Dopamine; Drug-Seeking Behavior; Mice; Mice, Transgenic; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Self Administration | 2022 |
Drug versus non-drug behaviors: A dual-reward model of sex differences and neurobiological mechanisms in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cues; Extinction, Psychological; Female; Male; Pharmaceutical Preparations; Rats; Reward; Sex Characteristics | 2022 |
Chronic cocaine causes age-dependent increases in risky choice in both males and females.
Topics: Animals; Cocaine; Decision Making; Female; Male; Rats; Rats, Long-Evans; Reward; Self Administration | 2022 |
Insula lesions reduce stimulus-driven control of behavior during odor-guided decision-making and autoshaping.
Topics: Animals; Choice Behavior; Cocaine; Decision Making; Odorants; Rats; Rats, Long-Evans; Reward | 2022 |
Effects of ketosis on cocaine-induced reinstatement in male mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Extinction, Psychological; Female; Humans; Ketosis; Male; Mice; Reward | 2022 |
Corticotropin releasing factor (CRF) systems: Promoting cocaine pursuit without distress via incentive motivation.
Topics: Animals; Central Amygdaloid Nucleus; Cocaine; Corticotropin-Releasing Hormone; Motivation; Rats; Reward | 2022 |
N-Oleoyl Glycine and Its Derivatives Attenuate the Acquisition and Expression of Cocaine-Induced Behaviors.
Topics: Animals; Cocaine; Endocannabinoids; Glycine; Mice; Nucleus Accumbens; Reward | 2023 |
Resilience to social defeat stress in adolescent male mice.
Topics: Animals; Cocaine; Ethanol; Interleukin-6; Male; Mice; Reward; Social Defeat; Stress, Psychological | 2022 |
Adolescent reinforcement-learning trajectories predict cocaine-taking behaviors in adult male and female rats.
Topics: Animals; Behavior, Addictive; Cocaine; Decision Making; Female; Male; Rats; Rats, Long-Evans; Reinforcement, Psychology; Reversal Learning; Reward | 2022 |
Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward.
Topics: Animals; Basal Forebrain; Cocaine; Gene Expression Profiling; Mice; Neurons; Reward; Thalamus | 2022 |
Reelin deficiency exacerbates cocaine-induced hyperlocomotion by enhancing neuronal activity in the dorsomedial striatum.
Topics: Adult; Animals; Cocaine; Corpus Striatum; Humans; In Situ Hybridization, Fluorescence; Mice; Neostriatum; Reward | 2022 |
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Doxycycline; HIV-1; Humans; Mice; Mice, Transgenic; Reward; tat Gene Products, Human Immunodeficiency Virus; Trans-Activators; Transcription Factor DP1 | 2022 |
Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward.
Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; Mice; Narcotic Antagonists; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; RNA, Messenger | 2022 |
Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females.
Topics: Amygdala; Animals; Cocaine; Female; Male; Mice; mu-Crystallins; Neurons; Reward | 2022 |
Repeated dosing with cocaine produces strain-dependent effects on responding for conditioned reinforcement in Collaborative Cross mice.
Topics: Animals; Cocaine; Collaborative Cross Mice; Dopamine; Dopamine Uptake Inhibitors; Female; Male; Mice; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2023 |
Nociceptive Stimuli Activate the Hypothalamus-Habenula Circuit to Inhibit the Mesolimbic Reward System and Cocaine-Seeking Behaviors.
Topics: Animals; Cocaine; Dopamine; Habenula; Hypothalamic Area, Lateral; Male; Nociception; Rats; Rats, Sprague-Dawley; Reward; Sensation; Ventral Tegmental Area | 2022 |
Large-scale brain correlates of sweet versus cocaine reward in rats.
Topics: Animals; Brain; Cocaine; Conditioning, Operant; Rats; Rats, Wistar; Reward; Saccharin; Taste; Water | 2023 |
Prelimbic and infralimbic medial prefrontal cortex neuron activity signals cocaine seeking variables across multiple timescales.
Topics: Cocaine; Cues; Drug-Seeking Behavior; Extinction, Psychological; Neurons; Prefrontal Cortex; Reward; Self Administration | 2023 |
Molecular pattern of a decrease in the rewarding effect of cocaine after an escalating-dose drug regimen.
Topics: Animals; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Corticosterone; MicroRNAs; Pro-Opiomelanocortin; Rats; Reward; RNA, Messenger | 2023 |
Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA.
Topics: Animals; Astrocytes; Cocaine; Dopaminergic Neurons; gamma-Aminobutyric Acid; Membrane Proteins; Mice; Receptors, GABA-A; Reward; Ventral Tegmental Area | 2023 |
Whole-brain tracking of cocaine and sugar rewards processing.
Topics: Animals; Cocaine; Neurons; Nucleus Accumbens; Reward; Sucrose; Sugars | 2023 |
Oleoylethanolamide attenuates the stress-mediated potentiation of rewarding properties of cocaine associated with an increased TLR4 proinflammatory response.
Topics: Animals; Cocaine; Mice; Oleic Acids; Reward; Toll-Like Receptor 4 | 2023 |
Behavioral encoding across timescales by region-specific dopamine dynamics.
Topics: Animals; Cocaine; Dopamine; Mice; Reward; Ventral Striatum | 2023 |
Effects of isolation housing stress and mouse strain on intravenous cocaine self-administration, sensory stimulus self-administration, and reward preference.
Topics: Animals; Cocaine; Housing; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reward; Self Administration | 2023 |
Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards.
Topics: Animals; Cocaine; Female; Male; Mental Disorders; Mice; Mice, Inbred C57BL; Neurons; Nucleus Accumbens; Receptors, Dopamine D1; Retinoid X Receptor alpha; Reward | 2023 |
The differential vulnerabilities of Per2 knockout mice to the addictive properties of methamphetamine and cocaine.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Methamphetamine; Mice; Mice, Knockout; Period Circadian Proteins; Reward | 2023 |
Deficits in consummatory reward relate to severity of cocaine use.
Topics: Adult; Anhedonia; Bayes Theorem; Cocaine; Cocaine-Related Disorders; Cross-Sectional Studies; Humans; Motivation; Pleasure; Reward | 2023 |
Resilience to the short- and long-term behavioral effects of intermittent repeated social defeat in adolescent male mice.
Topics: Animals; Cocaine; Male; Mice; Mice, Inbred C57BL; Reward; Social Defeat; Stress, Psychological | 2023 |
Subunit-selective PI3-kinase control of action strategies in the medial prefrontal cortex.
Topics: Animals; Cocaine; Mice; Phosphatidylinositol 3-Kinases; Prefrontal Cortex; Prospective Studies; Reward | 2023 |
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors.
Topics: Animals; Anxiety; Cocaine; HEK293 Cells; Humans; Locomotion; Mice; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward | 2023 |
α7 nicotinic acetylcholine receptors in the medial prefrontal cortex control rewarding but not aversive memory expression in a dopamine-sensitive manner.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Cocaine; Dopamine; Prefrontal Cortex; Receptors, Nicotinic; Reward | 2023 |
N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice.
Topics: Animals; Brain; Cocaine; Ethanol; Glycine; Mice; Nucleus Accumbens; Reward; Ventral Tegmental Area | 2023 |
Swell1 channel-mediated tonic GABA release from astrocytes modulates cocaine reward.
Topics: Astrocytes; Cocaine; gamma-Aminobutyric Acid; Reward; Synaptic Transmission | 2024 |
Endogenous opioid system modulates conditioned cocaine reward in a sex-dependent manner.
Topics: Analgesics, Opioid; Animals; Cocaine; Enkephalins; Female; Male; Mice; Naloxone; Narcotic Antagonists; Opioid Peptides; Reward | 2023 |
Doxycycline diminishes the rewarding and psychomotor effects induced by morphine and cocaine.
Topics: Animals; Cocaine; Doxycycline; Mice; Morphine; Reward; Substance-Related Disorders | 2024 |
Social defeat stress enhances the rewarding effects of cocaine through α
Topics: Animals; Cocaine; Male; Mice; Prefrontal Cortex; Receptors, Adrenergic; Reward; Social Defeat; Stress, Psychological | 2024 |
Cue- versus reward-encoding basolateral amygdala projections to nucleus accumbens.
Topics: Animals; Basolateral Nuclear Complex; Cocaine; Cues; Mice; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward | 2023 |