cocaine and risperidone

cocaine has been researched along with risperidone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.71)18.2507
2000's18 (64.29)29.6817
2010's6 (21.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA1
Lombardo, F; Obach, RS; Waters, NJ1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Roy, A; Roy, M; Smelson, DA2
Dashevsky, BA; Frank, RA; Grocki, S; Kehne, JH; Schmidt, CJ; Sorensen, SM; Tsibulsky, VL1
Bailey, R; Creson, D; Grabowski, J; Rhoades, H; Schmitz, JM; Silverman, P; Stotts, A1
Baldessarini, RJ; Tarazi, FI; Zhang, K1
Gessa, GL; Marchese, G; Pani, L; Ruiu, S; Saba, PL1
Kalechstein, AD; Ling, W; Newton, TF; Tervo, K; Uslaner, J1
Broderick, PA; Rahni, DN; Zhou, Y1
Cowan, K; Dougherty, A; Grabowski, J; Hassan, S; Kopecky, C; Moeller, FG; Rhoades, H; Schmitz, J; Stotts, A1
Clifton, PG; Hartfield, AW; Moore, NA1
Connor, DF; Melloni, RH; Morrison, RL; Ricci, LA; Schwartzer, JJ1
Alvarez, Y; Farré, M; Pérez-Mañá, C; Torrens, M1
Correll, CU; Iwata, N; Kishi, T; Matsuda, Y1
Banks, ML; Hutsell, BA; Negus, SS1
Makiguchi, A; Okada, T; Shioda, K; Suda, S1

Reviews

2 review(s) available for cocaine and risperidone

ArticleYear
Antipsychotic drugs in cocaine dependence: a systematic review and meta-analysis.
    Journal of substance abuse treatment, 2013, Volume: 45, Issue:1

    Topics: Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Humans; Outcome Assessment, Health Care; Patient Dropouts; Randomized Controlled Trials as Topic; Risperidone; Severity of Illness Index

2013
Antipsychotics for cocaine or psychostimulant dependence: systematic review and meta-analysis of randomized, placebo-controlled trials.
    The Journal of clinical psychiatry, 2013, Volume: 74, Issue:12

    Topics: Amphetamine-Related Disorders; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Humans; Methamphetamine; Olanzapine; Outcome Assessment, Health Care; Piperazines; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Substance Withdrawal Syndrome; Synaptic Transmission; Treatment Outcome

2013

Trials

3 trial(s) available for cocaine and risperidone

ArticleYear
Risperidone diminishes cue-elicited craving in withdrawn cocaine-dependent patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1997, Volume: 42, Issue:9

    Topics: Antipsychotic Agents; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Cues; Drive; Humans; Male; Prospective Studies; Risperidone; Substance Withdrawal Syndrome; Treatment Outcome

1997
Risperidone for the treatment of cocaine dependence: randomized, double-blind trial.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:3

    Topics: Adult; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Patient Dropouts; Psychotherapy; Recurrence; Risperidone; Time Factors

2000
Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence: two double-blind randomized clinical trials.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heroin Dependence; HIV Infections; Humans; Male; Methadone; Middle Aged; Narcotics; Patient Dropouts; Psychiatric Status Rating Scales; Risperidone; Substance Abuse Detection

2004

Other Studies

23 other study(ies) available for cocaine and risperidone

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A two-state homology model of the hERG K+ channel: application to ligand binding.
    Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Risperidone and neuropsychological test performance in cocaine-withdrawn patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1997, Volume: 42, Issue:4

    Topics: Adult; Antipsychotic Agents; Cocaine; Humans; Male; Neuropsychological Tests; Risperidone; Substance Withdrawal Syndrome; Substance-Related Disorders

1997
Mixed D2/5-HT2A antagonism of cocaine-induced facilitation of brain stimulation reward.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:2

    Topics: Animals; Brain; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reward; Risperidone; Self Stimulation; Serotonin Antagonists

1998
Olanzapine, quetiapine, and risperidone: long-term effects on monoamine transporters in rat forebrain.
    Neuroscience letters, 2000, Jun-23, Volume: 287, Issue:2

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Carrier Proteins; Caudate Nucleus; Cocaine; Dibenzothiazepines; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Olanzapine; Paroxetine; Pirenzepine; Prosencephalon; Putamen; Quetiapine Fumarate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium

2000
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
    Molecular psychiatry, 2000, Volume: 5, Issue:6

    Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium

2000
Risperidone pre-treatment reduces the euphoric effects of experimentally administered cocaine.
    Psychiatry research, 2001, Jul-24, Volume: 102, Issue:3

    Topics: Adult; Analysis of Variance; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dose-Response Relationship, Drug; Euphoria; Female; Humans; Male; Middle Aged; Risperidone; Serotonin Antagonists

2001
Acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior.
    Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:6

    Topics: Animals; Cocaine; Dopamine; Electrochemistry; Exploratory Behavior; Locomotion; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin

2003
Effects of atypical antipsychotic drugs on intralipid intake and cocaine-induced hyperactivity in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:9

    Topics: Animals; Antipsychotic Agents; Cocaine; Dibenzothiazepines; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Fat Emulsions, Intravenous; Female; Hyperkinesis; Male; Motor Activity; Piperazines; Quetiapine Fumarate; Rats; Risperidone; Thiazoles

2006
Repeated risperidone administration during puberty prevents the generation of the aggressive phenotype in a developmentally immature animal model of escalated aggression.
    Physiology & behavior, 2008, Sep-03, Volume: 95, Issue:1-2

    Topics: Age Factors; Aggression; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Body Weight; Cocaine; Cricetinae; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Mesocricetus; Phenotype; Reaction Time; Risperidone

2008
Effects of 21-day d-amphetamine and risperidone treatment on cocaine vs food choice and extended-access cocaine intake in male rhesus monkeys.
    Drug and alcohol dependence, 2016, Nov-01, Volume: 168

    Topics: Animals; Central Nervous System Stimulants; Choice Behavior; Cocaine; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Food; Macaca mulatta; Male; Risperidone; Self Administration

2016
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
    The international journal of neuropsychopharmacology, 2020, 12-29, Volume: 23, Issue:12

    Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists

2020