Compounds > cocaine

cocaine and rimcazole

cocaine has been researched along with rimcazole in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowen, WD; Husbands, SM; Izenwasser, S; Katz, JL; Kopajtic, T; Newman, AH; Vilner, BJ1
Cao, J; Husbands, SM; Katz, JL; Kopajtic, T; Newman, AH1
Bowen, WD; Cao, J; George, C; Husbands, SM; Katz, JL; Kopajtic, T; Kulkarni, SS; Newman, AH; Williams, W1
Bowen, WD; Husbands, SM; Izenwasser, S; Katz, JL; Loeloff, RJ; Newman, AH; Vilner, BJ1
Bowen, WD; Cao, JJ; Hewett, KL; Husbands, SM; Matsumoto, RR; Newman, AH; Pouw, B1
Husbands, SM; Katz, JL; Kopajtic, T; Libby, TA; Newman, AH1
Blakely, RD; Henry, LK1
Cao, J; Katz, JL; Kopajtic, T; Newman, AH1
Bartlett, PJ; Berwick, ZC; Chakraborty, S; Kumar, S; Obukhov, AG; Sturek, M; Thomas, AP; Tune, JD1
Cao, J; Hiranita, T; Katz, JL; Kohut, SJ; Kopajtic, T; Newman, AH; Soto, PL; Tanda, G1
Atluri, VSR; Jayant, RD; Kaushik, A; Nair, M; Pilakka-Kanthikeel, S; Tiwari, S; Yndart, A1

Other Studies

11 other study(ies) available for cocaine and rimcazole

ArticleYear
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.
    Journal of medicinal chemistry, 1999, Oct-21, Volume: 42, Issue:21

    Topics: Aniline Compounds; Animals; Brain; Carbazoles; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Guinea Pigs; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters

1999
[3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.
    Bioorganic & medicinal chemistry letters, 2001, Dec-17, Volume: 11, Issue:24

    Topics: Animals; Carbazoles; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Nerve Tissue Proteins; Piperazines; Rats

2001
Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
    Journal of medicinal chemistry, 2003, Jun-19, Volume: 46, Issue:13

    Topics: Animals; Binding, Competitive; Brain; Cocaine-Related Disorders; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Receptors, sigma; Structure-Activity Relationship

2003
Isothiocyanate derivatives of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole): irreversible ligands for the dopamine transporter.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carbazoles; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guinea Pigs; Isothiocyanates; Ligands; Liver; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Receptors, sigma

1997
Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters.
    Neuropharmacology, 2001, Volume: 41, Issue:7

    Topics: Animals; Anticonvulsants; Binding Sites; Carbazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Ethylamines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures

2001
Behavioral effects of rimcazole analogues alone and in combination with cocaine.
    European journal of pharmacology, 2003, May-09, Volume: 468, Issue:2

    Topics: Animals; Behavior, Animal; Carbazoles; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, sigma; Structure-Activity Relationship

2003
Distinctions between dopamine transporter antagonists could be just around the bend.
    Molecular pharmacology, 2008, Volume: 73, Issue:3

    Topics: Animals; Benztropine; Carbazoles; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Mice; Models, Molecular; Motor Activity; Protein Conformation; Protein Structure, Secondary; Rats

2008
Dual DAT/sigma1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropan-1-ol.
    Bioorganic & medicinal chemistry letters, 2008, Oct-01, Volume: 18, Issue:19

    Topics: Animals; Carbazoles; Cocaine; Combinatorial Chemistry Techniques; Dopamine Plasma Membrane Transport Proteins; Molecular Structure; Piperazines; Protein Binding; Rats; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship

2008
Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; Behavior, Addictive; Calcium Channels; Carbazoles; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Male; Naphthalenes; Phosphodiesterase Inhibitors; Phospholipases; Pyrones; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Self Administration; Swine; Thapsigargin; Transient Receptor Potential Channels

2011
Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Animals; Anisoles; Antipsychotic Agents; Carbazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Molecular Targeted Therapy; Oxalates; Piperidines; Propylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement, Psychology; Self Administration

2011
Novel nanoformulation to mitigate co-effects of drugs of abuse and HIV-1 infection: towards the treatment of NeuroAIDS.
    Journal of neurovirology, 2017, Volume: 23, Issue:4

    Topics: AIDS Dementia Complex; Astrocytes; Blood-Brain Barrier; Carbazoles; Cocaine; Delayed-Action Preparations; Endothelial Cells; HIV Protease Inhibitors; HIV-1; Humans; Illicit Drugs; Magnets; Methamphetamine; Nanostructures; Nelfinavir; Neuroprotective Agents; Primary Cell Culture; Substance Abuse, Intravenous

2017