cocaine and promethazine

cocaine has been researched along with promethazine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199020 (71.43)18.7374
1990's0 (0.00)18.2507
2000's5 (17.86)29.6817
2010's3 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Allan, D; Michell, RH1
Pierluisi, GJ; Terndrup, TE1
Bergman, J; Spealman, RD1
Tozzi, S1
Goth, A; Isaac, L2
Brody, TM; McNeill, JH1
Gokhale, SD; Gulati, OD; Udwadia, BP1
Slivko, SF1
Schrold, J1
el-Asmar, MF; Ibrahim, SA; Ismail, M; Osman, OH1
Mason, RG; Read, MS; Saba, SR; Shermer, RW1
Mannucci, PM; Sirigu, F1
Thomas, KB1
Brissie, RM; Fu, K; Hardy, RW; Konrad, RJ; Robinson, CA1
BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I1
CHITTAL, SM; SHETH, UK1
BOFF, E; SCHECKEL, CL1
STEWART, GA; YOUNG, PA1
DAY, M; STOCKBRIDGE, A1
de Jong, M; De Wael, K; Florea, A; Samyn, N; Sleegers, N; Van Loon, J; van Nuijs, ALN1

Other Studies

28 other study(ies) available for cocaine and promethazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Enhanced synthesis de novo of phosphatidylinositol in lymphocytes treated with cationic amphiphilic drugs.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Amphetamine; Animals; Cetrimonium Compounds; Chlorpromazine; Cocaine; Dibucaine; Dose-Response Relationship, Drug; Fenfluramine; Imipramine; Lectins; Lymphocytes; Phenethylamines; Phosphatidylinositols; Procaine; Promethazine; Swine; Time Factors; Trifluoperazine

1975
Influence of topical anesthesia on the sedation of pediatric emergency department patients with lacerations.
    Pediatric emergency care, 1989, Volume: 5, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Child, Preschool; Chlorpromazine; Cocaine; Drug Combinations; Drug Therapy, Combination; Emergencies; Epinephrine; Humans; Meperidine; Premedication; Promethazine; Retrospective Studies; Tetracaine; Wounds and Injuries

1989
Some behavioral effects of histamine H1 antagonists in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Animals; Behavior, Animal; Chlordiazepoxide; Chlorpheniramine; Cimetidine; Clozapine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diphenhydramine; Electroshock; Feeding Behavior; Histamine H1 Antagonists; Male; Promethazine; Saimiri; Self Administration; Tripelennamine

1986
The mechanism of action of histamine on the isolated rat uterus.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:3

    Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Promethazine; Propranolol; Rats; Reserpine; Tachyphylaxis; Tyramine; Uterus

1973
Interaction of antihistaminics with norepinephrine uptake: a cocaine-like effect.
    Life sciences, 1965, Volume: 4, Issue:19

    Topics: Animals; Chlorpheniramine; Cocaine; Heart; Histamine H1 Antagonists; In Vitro Techniques; Norepinephrine; Promethazine; Rats; Tripelennamine

1965
The effect of antihistaminics, cocaine and reserpine on amine-induced rat cardiac phosphorylase activation.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 152, Issue:3

    Topics: Animals; Cocaine; Drug Synergism; Glucosyltransferases; Histamine H1 Antagonists; Isoproterenol; Myocardium; Norepinephrine; Promethazine; Propranolol; Rats; Reserpine; Tripelennamine; Triprolidine

1966
Antagonism of the adrenergic neurone blocking action of guanethidine by certain antidepressant and antihistamine drugs.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 160, Issue:2

    Topics: Animals; Blood Pressure; Carotid Arteries; Cocaine; Dextroamphetamine; Dogs; Drug Antagonism; Guanethidine; Histamine H1 Antagonists; Hydrazines; Imipramine; Methamphetamine; Methylphenidate; Promethazine

1966
The mechanism of the potentiation of norepinephrine by antihistaminics.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:3

    Topics: Animals; Blood Pressure; Chlorpheniramine; Cocaine; Drug Synergism; Female; Heart; Heart Atria; Histamine H1 Antagonists; Isoproterenol; Norepinephrine; Pressoreceptors; Promethazine; Rats; Sympathetic Nervous System; Tripelennamine; Tritium

1967
[The effect of cholinomimetics, biogenic amines and their antagonists on the local anesthetic effect].
    Biulleten' eksperimental'noi biologii i meditsiny, 1967, Volume: 63, Issue:6

    Topics: Anesthesia, Local; Animals; Cocaine; Cornea; Diphenhydramine; Diphenylacetic Acids; Epinephrine; Guinea Pigs; Histamine; Nicotine; Pilocarpine; Promethazine; Sensory Receptor Cells; Serotonin; Sympatholytics; Sympathomimetics; Tetracaine

1967
Behavioural effects od d-amphetamine alone and in combination with antidepressants, antihistamines or other psychotropic drugs in young chicks.
    Psychopharmacologia, 1972, Volume: 23, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Chickens; Chlorpheniramine; Cocaine; Desipramine; Dextroamphetamine; Diphenhydramine; Drug Antagonism; Drug Interactions; Histamine H1 Antagonists; Imipramine; Male; Nortriptyline; Promethazine

1972
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
    Toxicon : official journal of the International Society on Toxinology, 1972, Volume: 10, Issue:4

    Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compounds; Kinins; Lysergic Acid Diethylamide; Methysergide; Muscle Contraction; ortho-Aminobenzoates; Papaverine; Pregnancy; Promethazine; Rats; Scorpions; Toluene; Tripelennamine; Uterus; Venoms

1972
Apparent similarity of mechanisms of platelet adhesion and aggregation. Differentiation of these functions from clot retraction.
    Thrombosis et diathesis haemorrhagica, 1972, Feb-29, Volume: 27, Issue:1

    Topics: Amitriptyline; Aspirin; Blood Coagulation Tests; Caffeine; Chloromercuribenzoates; Chlorpromazine; Clot Retraction; Cocaine; Diphenhydramine; Ethacrynic Acid; Guanidines; Humans; Phenothiazines; Phentolamine; Phenylbutazone; Platelet Adhesiveness; Promethazine; Quinacrine; Quinidine; Reserpine; Sulfinpyrazone; Sulfones; Tosyl Compounds

1972
Effect of inhibitors of aggregation on platelet ultrastructure in vitro.
    Thrombosis et diathesis haemorrhagica, 1969, Apr-30, Volume: 21, Issue:2

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Blood Platelets; Cocaine; Diphenhydramine; Epinephrine; Humans; In Vitro Techniques; Microscopy, Electron; Norepinephrine; Nucleosides; Phentolamine; Promethazine; Reserpine; Tendons; Thrombin; Tissue Extracts; Tryptamines

1969
Neuroleptanalgesia for cataract surgery.
    Acta anaesthesiologica Scandinavica. Supplementum, 1966, Volume: 24

    Topics: Adult; Aged; Anesthesia, Local; Benperidol; Cataract Extraction; Cocaine; Female; Humans; Hypoventilation; Lidocaine; Male; Middle Aged; Neuroleptanalgesia; Phenoperidine; Postoperative Complications; Preanesthetic Medication; Promethazine; Tonometry, Ocular

1966
An unusual multiple drug intoxication case involving citalopram.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Cocaine; Dextropropoxyphene; Drug Synergism; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Oxycodone; Promethazine; Selective Serotonin Reuptake Inhibitors; Tissue Distribution

2000
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
    Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental

1962
EFFECT OF DRUGS ON CONDITIONED AVOIDANCE RESPONSE IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1963, Aug-02, Volume: 144

    Topics: Avoidance Learning; Chlordiazepoxide; Chlorpromazine; Cocaine; Codeine; Conditioning, Operant; Ethanol; Hydroxyzine; Meperidine; Methylphenidate; Morphine; Pharmacology; Promethazine; Rats; Research; Sodium Salicylate

1963
BEHAVIORAL EFFECTS OF INTERACTING IMIPRAMINE AND OTHER DRUGS WITH D-AMPHETAMINE, COCAINE, AND TETRABENAZINE.
    Psychopharmacologia, 1964, Feb-12, Volume: 5

    Topics: Amitriptyline; Atropine; Avoidance Learning; Chlorpromazine; Cocaine; Desipramine; Dextroamphetamine; Guanethidine; Imipramine; Iproniazid; Isocarboxazid; Methylphenidate; Parasympatholytics; Pharmacology; Piperidines; Promazine; Promethazine; Rats; Research; Scopolamine; Tetrabenazine; Trihexyphenidyl; Tyramine

1964
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
    Progress in medicinal chemistry, 1963, Volume: 19

    Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine

1963
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
    British journal of pharmacology and chemotherapy, 1964, Volume: 23

    Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imipramine; Isoproterenol; Lysergic Acid Diethylamide; Mast Cells; Metabolism; Methysergide; Mice; Neoplasms; Neoplasms, Experimental; Norepinephrine; Pharmacology; Phenoxybenzamine; Promethazine; Research; Serotonin; Sympatholytics; Tryptamines

1964
Unraveling the Mechanisms Behind the Complete Suppression of Cocaine Electrochemical Signals by Chlorpromazine, Promethazine, Procaine, and Dextromethorphan.
    Analytical chemistry, 2019, 12-17, Volume: 91, Issue:24

    Topics: Anesthetics, Local; Antiemetics; Antipruritics; Antitussive Agents; Chlorpromazine; Cocaine; Dextromethorphan; Electrochemical Techniques; Molecular Structure; Procaine; Promethazine; Sensitivity and Specificity

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