cocaine has been researched along with proadifen in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Summers, RJ; Tillman, J | 1 |
| Shaw, K; Shuster, L; Thompson, ML | 1 |
| Englert, LF; Estevez, VS; Ho, BT | 2 |
| James, RC; Pounds, JG; Roberts, SM | 1 |
| Cornette, C; Lallemant, AM; Serrar, D; Thevenin, M | 1 |
| Kobrinski, E; Saxon, M | 1 |
| Kato, R; Onoda, K; Takayanagi, M | 1 |
| Goodman, DR; Harbison, RD; James, RC | 1 |
| May, DA; Shah, NS; Yates, JD | 1 |
| Ross, SB | 1 |
| Greenblatt, DJ; LeDuc, BW; Shuster, L; Sinclair, JF; Sinclair, PR; Walton, HS | 1 |
| Abdel-Rahman, MS; Labib, R; Turkall, R | 1 |
| Houlihan, WJ; Kelly, L | 1 |
| Chang, HW; Holsapple, MP; Jeon, TW; Jeong, HG; Jeong, TC; Lee, ES | 1 |
16 other study(ies) available for cocaine and proadifen
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Investigation of the role of calcium in the supersensitivity produced by cocaine in cat spleen strips.
Topics: Angiotensin II; Animals; Calcium; Cats; Chlorpheniramine; Cocaine; Desipramine; Drug Interactions; Female; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Oxymetazoline; Potassium; Proadifen; Spleen | 1979 |
Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Proadifen; Sleep | 1979 |
Metabolism correlates of cocaine-induced stereotypy in rats.
Topics: Animals; Behavior; Brain Chemistry; Cocaine; Female; Humans; Proadifen; Rats; Stereotyped Behavior; Time Factors | 1979 |
Inhibition of the metabolism of cocaine by SKF-525A.
Topics: Animals; Brain; Cocaine; Depression, Chemical; Hydrolysis; In Vitro Techniques; Liver; Lung; Motor Activity; Proadifen; Rats | 1977 |
Cocaine toxicity in cultured rat hepatocytes.
Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1990 |
[Modifications of the hepatotoxicity of cocaine on Swiss mice by various inhibitors].
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cholesterol; Cocaine; Diazinon; Insecticides; Liver; Male; Maleates; Mice; Proadifen; Triglycerides | 1985 |
Two types of spontaneous contractions in rat myocardium and their possible relation to different Ca release processes.
Topics: Animals; Calcium; Cocaine; Dantrolene; In Vitro Techniques; Lidocaine; Myocardial Contraction; Myocardium; Proadifen; Rats; Rats, Inbred Strains | 1986 |
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine | 1969 |
Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics.
Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Narcotics; Proadifen; Time Factors | 1982 |
Disposition of levo-[3H]cocaine in pregnant and nonpregnant mice.
Topics: Animals; Cocaine; Female; Male; Maternal-Fetal Exchange; Mice; Pregnancy; Pregnancy, Animal; Proadifen; Stereoisomerism; Time Factors; Tissue Distribution | 1980 |
Comparison of high affinity binding of 3H-proadifen and 3H-(-)-cocaine to rat liver membranes.
Topics: Alanine; Animals; Binding, Competitive; Cadmium; Cadmium Chloride; Chlorides; Cocaine; Liver; Male; Microsomes, Liver; Proadifen; Rats; Rats, Sprague-Dawley; Subcellular Fractions | 1995 |
Cocaine toxicity in cultured chicken hepatocytes: role of cytochrome P450.
Topics: Allylisopropylacetamide; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Immunoblotting; L-Lactate Dehydrogenase; Liver; Methylcholanthrene; Models, Biological; Porphyrins; Proadifen; Protein Biosynthesis | 1994 |
Inhibition of cocaine oxidative metabolism attenuates endotoxin potentiation of cocaine mediated hepatotoxicity.
Topics: Animals; Biotransformation; Catalase; Chemical and Drug Induced Liver Injury; Cocaine; Endotoxins; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lipopolysaccharides; Liver; Liver Function Tests; Male; Mice; Oxidation-Reduction; Proadifen | 2002 |
Assessment of mazindane, a pro-drug form of mazindol, in assays used to define cocaine treatment agents.
Topics: Analysis of Variance; Animals; Binding, Competitive; Cell Membrane; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Isoindoles; Macaca mulatta; Male; Mazindol; Mice; Motor Activity; Neurotransmitter Agents; Proadifen; Rats; Rats, Sprague-Dawley; Tritium | 2003 |
Skf 525-A induces cocaine N-demethylase, ethoxyresorufin O-deethylase, and pentoxyresorufin O-dealkylase activities by induction of cytochrome p-450 2B in female B6C3F1 mice.
Topics: Animals; Cocaine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Mice; Oxidoreductases, N-Demethylating; Proadifen | 2004 |