cocaine and prilocaine

cocaine has been researched along with prilocaine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199011 (47.83)18.7374
1990's6 (26.09)18.2507
2000's4 (17.39)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y1
Brouillette, WJ; Brown, GB; Zha, C1
de Jong, RH1
el-Kholy, A1
Whittet, HB; Williams, HO; Wright, A1
Belt, WD; Benoit, PW1
Paton, DM1
Geddes, IC1
Cheong, DK; Gangarosa, LP1
Frewin, DB; Gerke, DC1
Jyväkorpi, M1
Doyle, E; Russell, SC1
Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD1
Barrett, T; Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD1
Sleth, JC1
Keyes, PD; Rizos, J; Tallon, JM1
Caló, G; Joyce, PI; Lambert, DG; Rizzi, D; Rowbotham, DJ1
THORNTON, JA1
Guay, J1
Jero, J; Luukkainen, V; Sinkkonen, ST1

Reviews

3 review(s) available for cocaine and prilocaine

ArticleYear
A risk-benefit assessment of topical percutaneous local anaesthetics in children.
    Drug safety, 1997, Volume: 16, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Anaphylaxis; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Synergism; Epinephrine; Ethyl Chloride; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Narcotics; Ointments; Prilocaine; Risk Assessment; Skin Absorption; Tetracaine

1997
Topical anesthesia.
    Canadian family physician Medecin de famille canadien, 1998, Volume: 44

    Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Patient Selection; Prilocaine; Research Design; Suture Techniques; Tetracaine; Wounds and Injuries

1998
Methemoglobinemia related to local anesthetics: a summary of 242 episodes.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Cocaine; Female; Hemoglobins; Humans; Infant; Lidocaine; Male; Methemoglobinemia; Middle Aged; Pregnancy; Prilocaine; Tetracaine; Young Adult

2009

Trials

3 trial(s) available for cocaine and prilocaine

ArticleYear
An evaluation of topical anaesthesia for myringotomy.
    Clinical otolaryngology and allied sciences, 1988, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthetics, Local; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Middle Ear Ventilation; Pain Measurement; Prilocaine; Prospective Studies

1988
New non-cocaine-containing topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
    Pediatrics, 1997, Volume: 100, Issue:5

    Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Epinephrine; Female; Humans; Infant; Lidocaine; Male; Pain; Phenylephrine; Prilocaine; Prospective Studies; Suture Techniques; Tetracaine; Wounds and Injuries

1997
Prilocaine-phenylephrine and bupivacaine-phenylephrine topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
    The American journal of emergency medicine, 1998, Volume: 16, Issue:2

    Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cocaine; Dermatologic Surgical Procedures; Double-Blind Method; Emergency Service, Hospital; Epinephrine; Female; Hospitals, Pediatric; Humans; Infant; Male; Pain; Pain Measurement; Phenylephrine; Prilocaine; Prospective Studies; Safety; Skin; Suture Techniques; Tetracaine; Vasoconstrictor Agents

1998

Other Studies

17 other study(ies) available for cocaine and prilocaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship

2009
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Biotransformation of local anesthetics: General concepts.
    International anesthesiology clinics, 1975,Winter, Volume: 13, Issue:4

    Topics: Anesthetics, Local; Animals; Biotransformation; Cocaine; Humans; Lidocaine; Mepivacaine; Prilocaine; Procainamide; Procaine

1975
Which local anaesthetic?
    Drug and therapeutics bulletin, 1976, Feb-27, Volume: 14, Issue:5

    Topics: Administration, Topical; Anesthesia, Conduction; Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Local; Bupivacaine; Cocaine; Humans; Lidocaine; Nerve Block; Prilocaine

1976
Manipulation of the fractured nose using topical local anaesthesia.
    The Journal of laryngology and otology, 1989, Volume: 103, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Anesthesia, Local; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Manipulation, Orthopedic; Nasal Bone; Prilocaine; Skull Fractures

1989
Some effects of local anesthetic agents on skeletal muscle.
    Experimental neurology, 1972, Volume: 34, Issue:2

    Topics: Anesthesia, Local; Anesthetics; Animals; Bupivacaine; Cocaine; Lidocaine; Male; Mepivacaine; Muscles; Prilocaine; Procaine; Rats

1972
Effect of local anaesthetics on the accumulation of ( 3 H)-metaraminol by rabbit atria and vasa deferentia.
    Experientia, 1972, Oct-15, Volume: 28, Issue:10

    Topics: Anesthetics, Local; Animals; Cocaine; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male; Metaraminol; Myocardium; Prilocaine; Procaine; Rabbits; Tritium; Vas Deferens

1972
Local anaesthetics.
    Laval medical, 1971, Volume: 42, Issue:8

    Topics: Amides; Anesthetics, Local; Brain Edema; Cardiovascular Diseases; Central Nervous System Diseases; Cocaine; Dibucaine; Drug Hypersensitivity; Esters; Humans; Hypoxia; Lidocaine; Methemoglobinemia; Prilocaine; Procaine

1971
Local anesthetics: inhibition of subcutaneous absorption in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:4

    Topics: Absorption; Animals; Antipyrine; Cocaine; Depression, Chemical; Injections, Subcutaneous; Lidocaine; Phosphates; Phosphorus Isotopes; Prilocaine; Procaine; Rats; Tetracaine

1970
The comparative effects of prilocaine, lignocaine and cocaine on the response of the rabbit ear artery to adrenaline and noradrenaline.
    Australian dental journal, 1982, Volume: 27, Issue:1

    Topics: Animals; Arteries; Blood Pressure; Cocaine; Drug Combinations; Drug Synergism; Ear, External; Epinephrine; Lidocaine; Norepinephrine; Perfusion; Prilocaine; Rabbits

1982
A comparison of topical Emla cream with Bonain's solution for anesthesia of the tympanic membrane during tympanocentesis.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1996, Volume: 253, Issue:4-5

    Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Menthol; Middle Aged; Middle Ear Ventilation; Ointments; Pain Measurement; Phenols; Prilocaine; Solutions; Tympanic Membrane

1996
[The Bonain anesthetic mixture: a forgotten ancestor of Emla cream?].
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:4

    Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Menthol; Ointments; Phenols; Prilocaine

1998
The effect of guanethidine and local anesthetics on the electrically stimulated mouse vas deferens.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:5

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Cocaine; Electric Stimulation; Guanethidine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Prazosin; Prilocaine; Procaine; Tetrodotoxin; Vas Deferens

2002
RECENT ADVANCES IN LOCAL ANALGESIA. CLINICAL EXPERIENCE WITH PRILOCAINE.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58

    Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Bronchoscopy; Cocaine; Humans; Lidocaine; Pain; Pharmacology; Prilocaine; Statistics as Topic; Tetracaine; Toxicology

1965
Balloon Eustachian tuboplasty under monitored anaesthesia care with different balloon dilation devices: A pilot feasibility study with 18 patients.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2019, Volume: 44, Issue:1

    Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; Dilatation; Epinephrine; Eustachian Tube; Feasibility Studies; Female; Humans; Lidocaine; Male; Middle Aged; Pain Measurement; Pilot Projects; Prilocaine

2019