cocaine has been researched along with pirenzepine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Flynn, DD; Mash, DC; Vaishnav, AA | 1 |
| Choo, LK; Mitchelson, F | 1 |
| Cost, M; Majewski, H | 1 |
| Hanson, RC; Kuhar, MJ; Ritz, MC; Schenden, JA; Sharkey, J | 1 |
| Costa, LG; Tan, XX | 1 |
| Meil, WM; Schechter, MD | 1 |
| Allen, AC; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH | 1 |
| Baldessarini, RJ; Tarazi, FI; Zhang, K | 1 |
| Longo, LP | 1 |
| Kampman, KM; Lynch, KG; O'Brien, CP; Pettinati, H; Sparkman, T | 1 |
| Hayase, T; Muso, E; Shiota, K; Yamamoto, K; Yamamoto, Y | 1 |
| Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH | 1 |
| Carrigan, KA; Dykstra, LA | 1 |
| Katz, JL; Tanda, G | 1 |
| Donovan, DM; Katz, JL; Kopajtic, TA; Liu, Y; Newman, AH; Surratt, CK | 1 |
1 trial(s) available for cocaine and pirenzepine
| Article | Year |
|---|---|
A pilot trial of olanzapine for the treatment of cocaine dependence.
Topics: Adolescent; Adult; Benzodiazepines; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Olanzapine; Pilot Projects; Pirenzepine; Retention, Psychology; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
15 other study(ies) available for cocaine and pirenzepine
| Article | Year |
|---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Interactions of cocaine with primary and secondary recognition sites on muscarinic receptors.
Topics: Adult; Allosteric Site; Binding Sites; Brain Stem; Carbachol; Cocaine; Ethylmaleimide; Guanine Nucleotides; Humans; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1992 |
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium Compounds; Carbachol; Cocaine; Electric Stimulation; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pancuronium; Pirenzepine; Rabbits; Vas Deferens | 1990 |
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cocaine; Diamines; Dicyclomine; Female; Heart; Hexamethonium Compounds; In Vitro Techniques; Mice; Myocardium; Nerve Endings; Neurons; Norepinephrine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Sympathetic Nervous System; Synaptic Transmission | 1991 |
Cocaine inhibits muscarinic cholinergic receptors in heart and brain.
Topics: Animals; Brain; Cocaine; Heart Atria; Male; Methacholine Chloride; Methacholine Compounds; Myocardial Contraction; Myocardium; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain.
Topics: Animals; Brain Chemistry; Carbachol; Cerebral Cortex; Cocaine; Female; Male; Muscarinic Antagonists; Neurotransmitter Uptake Inhibitors; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Rats; Rats, Sprague-Dawley | 1994 |
Olanzapine attenuates the reinforcing effects of cocaine.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Food Preferences; Male; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Self Administration | 1997 |
Novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine.
Topics: Animals; Cocaine; Discrimination Learning; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Pirenzepine; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Tropanes | 1999 |
Olanzapine, quetiapine, and risperidone: long-term effects on monoamine transporters in rat forebrain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Carrier Proteins; Caudate Nucleus; Cocaine; Dibenzothiazepines; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Olanzapine; Paroxetine; Pirenzepine; Prosencephalon; Putamen; Quetiapine Fumarate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium | 2000 |
Olanzapine for cocaine craving and relapse prevention in 2 patients.
Topics: Adult; Antipsychotic Agents; Behavior, Addictive; Benzodiazepines; Cocaine-Related Disorders; Crack Cocaine; Drug Administration Schedule; Female; Humans; Male; Olanzapine; Pirenzepine; Secondary Prevention | 2002 |
Stressor-like effects of cocaine on heat shock protein and stress-activated protein kinase expression in the rat hippocampus: interaction with ethanol and anti-toxicity drugs.
Topics: Animals; Azides; Benzazepines; Benzodiazepines; Central Nervous System Depressants; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Ethanol; Heat-Shock Proteins; Hippocampus; Infusions, Parenteral; Ketanserin; Male; Mitogen-Activated Protein Kinases; Motor Activity; Muscarinic Antagonists; Pirenzepine; Rats; Serotonin Antagonists; Swimming | 2003 |
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.
Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine | 2005 |
Behavioral effects of morphine and cocaine in M1 muscarinic acetylcholine receptor-deficient mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Muscarinic Antagonists; Pain Measurement; Pain Threshold; Pirenzepine; Receptor, Muscarinic M1; Reward | 2007 |
Muscarinic preferential M(1) receptor antagonists enhance the discriminative-stimulus effects of cocaine in rats.
Topics: Animals; Cocaine; Data Interpretation, Statistical; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Trihexyphenidyl | 2007 |
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.
Topics: Adrenergic Uptake Inhibitors; Animals; Benztropine; Binding, Competitive; Cell Line, Tumor; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Mice; Mice, 129 Strain; Mice, Inbred Strains; Mice, Knockout; Neuroblastoma; Piperazines; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Selective Serotonin Reuptake Inhibitors; Sodium; Triprolidine | 2010 |