cocaine and phenobarbital

cocaine has been researched along with phenobarbital in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199030 (51.72)18.7374
1990's17 (29.31)18.2507
2000's8 (13.79)29.6817
2010's3 (5.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Burstein, Y; Giardina, PJ; Kandall, SR; Peterson, CM; Rausen, AR; Siljestrom, K1
Shaw, K; Shuster, L; Thompson, ML1
Borisenko, SA; Burov, IuV1
Harbison, RD; James, RC; Roberts, SM; Roth, L; Tobin, T1
Harbison, RD; James, RC; Roberts, SM; Roth, L1
Ammann, H; Vinet, B1
Tortella, FC; Witkin, JM1
Charles, SJ; Connolly, AK; Powell, CJ1
Conway, EE; Mezey, AP; Powers, K1
James, RC; Pounds, JG; Roberts, SM1
Ernst, AA; Sanders, WM1
Durand, DJ; Fulroth, R; Phillips, B1
Gomez, J; Rodriguez, A1
Brendel, K; Conners, S; Krumdieck, CL; Rankin, DR1
Benuck, M; Lajtha, A; Reith, ME; Sershen, H; Wiener, HL1
Wessinger, WD1
Burton, BT; Daya, MR; DiLiberti, JH; Schleiss, MR1
Boyer, CS; Petersen, DR; Ross, D1
Calligaro, DO; el-Maghrabi, EA; Eldefrawi, ME1
Goldenberg, GJ1
Frings, CS; Queen, CA1
Kazama, K1
McCarthy, WJ; St John, PA; Winefordner, JD1
Evans, HE; Glass, L1
Bertels-Meeuws, MM; Polak, RL1
Lajtha, A; Toth, J1
Freeman, RW; Harbison, RD; Teaf, CM1
Horiuchi, M; Inoue, Y; Yamamoto, K; Yoshimura, K1
Emley, GS; Hutchinson, RR1
Gilbert, LM; Golz, A; Komorowski, FS; Westerman, ST1
Evans, MA1
Yamamoto, K; Yoshimura, K1
Braithwaite, RA; George, S1
Alvarez, A; Boscá, L; Cascales, M; Fernández-Simón, L; Gascó, P; Sanz, N1
Castell, JV; Gómez-Lechón, J; Jover, R; Ponsoda, X1
Murphy, JL1
Aoki, K; Kuroiwa, Y; Yoshida, T1
Halpert, JR; McQueen, CA; Poet, TS1
Carter, RB; Gasior, M; Goldberg, SR; Witkin, JM1
Bornheim, LM1
Abdel-Rahman, MS; Figliomeni, ML1
Alvarez, AM; Cascales, M; Díez-Fernández, C; Zaragoza, A1
Aoki, K; Ota, H; Takimoto, M; Yoshida, T1
Egan-Hafley, M; Liang, S; Moore, DD; Wei, P; Zhang, J1
Fukui, Y; Hayase, T; Yamamoto, K; Yamamoto, Y1
MEIDINGER, F1
BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I1
OHTSUKI, I; OZAWA, H1
TEUCHMANN, JK; WIGLUSZ, Z1
Caligara, M; Campobasso, CP; Gherardi, M; Introna, F; Sironi, L1
Forcelli, PA; Gale, K; Gutherz, SB; Kondratyev, A; Kulick, CV; Soper, C1

Reviews

1 review(s) available for cocaine and phenobarbital

ArticleYear
Phosphorimetry as an analytical approach in biochemistry.
    Methods of biochemical analysis, 1967, Volume: 15

    Topics: Animals; Anticoagulants; Aspirin; Atropine; Blood Chemical Analysis; Chemical Phenomena; Chemistry, Physical; Chlorpromazine; Chromatography; Cocaine; Cold Temperature; Enzymes; Equipment and Supplies; Hot Temperature; Luminescent Measurements; Methods; Nitrophenols; Nucleic Acids; Phenobarbital; Procaine; Proteins; Solvents; Sulfonamides; Time Factors

1967

Other Studies

57 other study(ies) available for cocaine and phenobarbital

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Thrombocytosis and increased circulating platelet aggregates in newborn infants of polydrug users.
    The Journal of pediatrics, 1979, Volume: 94, Issue:6

    Topics: Amphetamine; Cocaine; Diazepam; Female; Heroin Dependence; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Morphine Dependence; Phenobarbital; Platelet Aggregation; Substance Withdrawal Syndrome; Substance-Related Disorders; Thrombocytosis

1979
Cocaine-induced hepatic necrosis in mice--the role of cocaine metabolism.
    Biochemical pharmacology, 1979, Aug-01, Volume: 28, Issue:15

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cocaine; Male; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Proadifen; Sleep

1979
[The effect of psychotropic substances on the mental and physical work capacity of rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:2

    Topics: Amphetamine; Animals; Benactyzine; Caffeine; Chlordiazepoxide; Cocaine; Diazepam; Disability Evaluation; Electric Stimulation; Learning; Male; Meprobamate; Morphine; Phenobarbital; Psychotropic Drugs; Rats; Reinforcement, Psychology; Self Stimulation; Stimulation, Chemical; Work Capacity Evaluation

1975
Cocaine hepatotoxicity: influence of hepatic enzyme inducing and inhibiting agents on the site of necrosis.
    Hepatology (Baltimore, Md.), 1992, Volume: 15, Issue:5

    Topics: Alanine Transaminase; Animals; Benzoflavones; beta-Naphthoflavone; Cocaine; Liver; Male; Necrosis; Norisoprenoids; Phenobarbital; Rats; Rats, Inbred Strains; Terpenes

1992
Cocaethylene hepatotoxicity in mice.
    Biochemical pharmacology, 1992, May-08, Volume: 43, Issue:9

    Topics: Alanine Transaminase; Animals; Benzoflavones; beta-Naphthoflavone; Cocaine; Diazinon; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Necrosis; Phenobarbital

1992
Accuracy, precision, and interferences of three modified EMIT procedures for determining serum phenobarbital, urine morphine, and urine cocaine metabolite with a Cobas-Fara.
    Clinical chemistry, 1991, Volume: 37, Issue:12

    Topics: Autoanalysis; Cocaine; Humans; Immunoenzyme Techniques; Morphine; Phenobarbital

1991
Modulators of N-methyl-D-aspartate protect against diazepam- or phenobarbital-resistant cocaine convulsions.
    Life sciences, 1991, Volume: 48, Issue:11

    Topics: Amino Acids; Animals; Anticonvulsants; Cocaine; Diazepam; Dizocilpine Maleate; Male; Mice; Phencyclidine; Phenobarbital; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors

1991
Shifting necrosis: butylated hydroxytoluene (BHT) and phenobarbital move cocaine-induced hepatic necrosis across the lobule.
    Toxicology letters, 1991, Volume: 55, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Butylated Hydroxytoluene; Cocaine; Drug Interactions; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Inbred DBA; Microsomes, Liver; Necrosis; Organ Size; Phenobarbital

1991
Status epilepticus following the oral ingestion of cocaine in an infant.
    Pediatric emergency care, 1990, Volume: 6, Issue:3

    Topics: Cocaine; Diagnosis, Differential; Diazepam; Electroencephalography; Emergencies; Humans; Infant; Male; Phenobarbital; Phenytoin; Status Epilepticus

1990
Cocaine toxicity in cultured rat hepatocytes.
    Toxicology letters, 1990, Volume: 50, Issue:2-3

    Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains

1990
Unexpected cocaine intoxication presenting as seizures in children.
    Annals of emergency medicine, 1989, Volume: 18, Issue:7

    Topics: Child, Preschool; Cocaine; Diazepam; Emergencies; Female; Gastric Lavage; Humans; Infant; Male; Phenobarbital; Seizures

1989
Perinatal outcome of infants exposed to cocaine and/or heroin in utero.
    American journal of diseases of children (1960), 1989, Volume: 143, Issue:8

    Topics: Cocaine; Drug Synergism; Female; Fetal Growth Retardation; Heroin; Humans; Infant, Newborn; Microcephaly; Obstetric Labor, Premature; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Substance Withdrawal Syndrome

1989
An evaluation of the results of a drug sample analysis.
    Bulletin on narcotics, 1989, Volume: 41, Issue:1-2

    Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders

1989
Interactive toxicity of cocaine with phenobarbital, morphine and ethanol in organ cultured human and rat liver slices.
    Proceedings of the Western Pharmacology Society, 1989, Volume: 32

    Topics: Animals; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Drug Interactions; Ethanol; Humans; Liver; Male; Morphine; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Inbred Strains

1989
Oxidative metabolism of cocaine: comparison of brain and liver.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 190, Issue:1

    Topics: Animals; Biotransformation; Brain; Chloral Hydrate; Cocaine; Diazinon; Liver; Male; Mice; Mice, Inbred BALB C; Microsomes; Microsomes, Liver; Organ Specificity; Phenobarbital; Reference Values

1989
Approaches to the study of drug interactions in behavioral pharmacology.
    Neuroscience and biobehavioral reviews, 1986,Summer, Volume: 10, Issue:2

    Topics: Alkaloids; Animals; Behavior, Animal; Brain; Chloral Hydrate; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Haloperidol; Humans; Phencyclidine; Phenobarbital; Synaptic Transmission

1986
Recurrent seizures following mucosal application of TAC.
    Annals of emergency medicine, 1988, Volume: 17, Issue:6

    Topics: Administration, Buccal; Anesthetics, Local; Child, Preschool; Cocaine; Drug Combinations; Epilepsy, Tonic-Clonic; Epinephrine; Humans; Male; Phenobarbital; Tetracaine

1988
Sex and strain differences in the hepatotoxic response to acute cocaine administration in the mouse.
    Journal of biochemical toxicology, 1988,Winter, Volume: 3

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Mice; Phenobarbital; Sex Factors; Species Specificity

1988
High affinity binding of [3H] cocaine to rat liver microsomes.
    Life sciences, 1988, Volume: 42, Issue:17

    Topics: Amines; Animals; Cations, Monovalent; Cocaine; Enzyme Induction; Guinea Pigs; Humans; Kinetics; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity; Tritium

1988
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
    Cancer research, 1974, Volume: 34, Issue:10

    Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Cell Line; Cells, Cultured; Choline; Cocaine; Cyclopentanes; Diazepam; Glucose; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Mice; Morphine; Phenobarbital; Stimulation, Chemical

1974
Stability of certain drugs of abuse in urine specimens.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Substance-Related Disorders; Temperature

1972
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1972, Volume: 74, Issue:7

    Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine

1972
Narcotic withdrawal in the newborn.
    American family physician, 1972, Volume: 6, Issue:1

    Topics: Birth Weight; Chlorpromazine; Cocaine; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methadone; Phenobarbital; Pregnancy; Prognosis; Substance Withdrawal Syndrome; Substance-Related Disorders

1972
Influence of antimuscarinic substances on in vitro synthesis of acetylcholine by rat cerebral cortex.
    British journal of pharmacology and chemotherapy, 1968, Volume: 33, Issue:2

    Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Cerebral Cortex; Cholinesterase Inhibitors; Cocaine; Female; In Vitro Techniques; Lysergic Acid Diethylamide; Phenobarbital; Physostigmine; Plants, Medicinal; Plants, Toxic; Potassium; Rats; Scopolamine

1968
The effects of drugs on uptake and exit of cerebral amino acids.
    Biochemical pharmacology, 1965, Volume: 14, Issue:5

    Topics: Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Brain; Chlorpromazine; Cocaine; Hypothermia, Induced; Lysergic Acid Diethylamide; Lysine; Mescaline; Mice; Morphine; Ouabain; Pentobarbital; Phenobarbital; Reserpine

1965
Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:4

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital

1984
[Pharmacological studies on drug dependence. (III): Intravenous self-administration of some CNS-affecting drugs and a new sleep-inducer, 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:1

    Topics: Animals; Central Nervous System Agents; Cocaine; Diazepam; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Methamphetamine; Morphine Dependence; Pentazocine; Phenobarbital; Rats; Rats, Inbred Strains; Self Administration; Substance-Related Disorders; Triazoles

1984
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:1

    Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri

1983
Qualitative measurement of drugs.
    The Laryngoscope, 1984, Volume: 94, Issue:2 Pt 1

    Topics: Adult; Anesthetics; Cocaine; Dextroamphetamine; Double-Blind Method; Electronystagmography; Evoked Potentials; Humans; Infant, Newborn; Meperidine; Middle Aged; Morphine; Nystagmus, Physiologic; Phenobarbital; Secobarbital

1984
Role of protein binding in cocaine-induced hepatic necrosis.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:1

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cricetinae; Esterases; Guinea Pigs; Liver Diseases; Male; Mesocricetus; Mice; Microsomes, Liver; Necrosis; Organ Specificity; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Time Factors

1983
[Neuropharmacological studies on drug dependence (II). Changes in spontaneous motor activity, EEG and brain monoamines during the period of dependence development and of abrupt withdrawal in rats, with special reference to circadian rhythm (author's trans
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:5

    Topics: Animals; Biogenic Amines; Brain; Circadian Rhythm; Cocaine; Diazepam; Electroencephalography; Humans; Male; Methamphetamine; Morphine Dependence; Motor Activity; Opioid-Related Disorders; Phenobarbital; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders

1980
Drugs of abuse screening in the West Midlands: a 6 year retrospective survey of results.
    Annals of clinical biochemistry, 1994, Volume: 31 ( Pt 5)

    Topics: Amphetamine; Cannabinoids; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Phenobarbital; Retrospective Studies; Substance-Related Disorders; United Kingdom

1994
Cocaine-induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:4 Pt 1

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Division; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Flow Cytometry; Glutathione; Isocitrate Dehydrogenase; Liver; Liver Regeneration; Male; Malondialdehyde; Mice; NADP; Necrosis; Phenobarbital; Ploidies; Polyploidy; Time Factors

1994
Cocaine hepatotoxicity: two different toxicity mechanisms for phenobarbital-induced and non-induced rat hepatocytes.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Cocaine; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Liver; Male; Oxidoreductases; Phenobarbital; Rats; Rats, Sprague-Dawley

1993
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:2

    Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ketamine; Lidocaine; Phenobarbital; Pulmonary Edema; Substance-Related Disorders; Tachycardia

1993
Forensic immunochemistry.
    Forensic science international, 1996, Jun-28, Volume: 80, Issue:1-2

    Topics: Central Nervous System Agents; Cocaine; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Humans; Latex Fixation Tests; Methamphetamine; Morphine; Phenobarbital; Radioimmunoassay; Sensitivity and Specificity; Substance-Related Disorders

1996
Participation of cytochromes P4502B and P4503A in cocaine toxicity in rat hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:1

    Topics: Animals; Cell Line; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dogs; Enzyme Induction; Guinea Pigs; Humans; Hydroxylation; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity

1996
Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: Animals; Anticonvulsants; Cocaine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Neuroprotective Agents; Phenobarbital; Steroids

1997
Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity.
    Toxicology and applied pharmacology, 1998, Volume: 150, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoenzymes; Liver; Male; Mice; Narcotics; Phencyclidine; Phenobarbital

1998
Ethanol does not increase the hepatotoxicity of cocaine in primary rat hepatocyte culture.
    Toxicology, 1998, Aug-21, Volume: 129, Issue:2-3

    Topics: Animals; Cells, Cultured; Cocaine; Drug Synergism; Ethanol; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley

1998
Cocaine cytotoxicity in hepatocyte cultures from phenobarbital-induced rats: involvement of reactive oxygen species and expression of antioxidant defense systems.
    Biochemical pharmacology, 1999, Sep-01, Volume: 58, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Catalase; Cells, Cultured; Cocaine; Gene Expression Regulation, Enzymologic; Liver; Male; Oxidative Stress; Phenobarbital; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase

1999
Participation of CYP2A in cocaine-induced hepatotoxicity in female mice.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:1

    Topics: Alanine Transaminase; Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Enzyme Activators; Enzyme Induction; Female; Liver Diseases; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Steroid Hydroxylases

2000
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism.
    Nature, 2000, Oct-19, Volume: 407, Issue:6806

    Topics: Alanine Transaminase; Animals; Aryl Hydrocarbon Hydroxylases; Cell Line; Cocaine; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Gene Targeting; Humans; Liver; Male; Mice; Pharmaceutical Preparations; Phenobarbital; Pyridines; Receptors, Virus; Steroid Hydroxylases; Xenobiotics; Zoxazolamine

2000
Comparison of effect of ethanol and anticonvulsants on cardiovascular drug-modified cocaine toxicity.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:1

    Topics: Animals; Anticonvulsants; Cardiovascular Agents; Cocaine; Diazepam; Enalapril; Ethanol; Male; Mice; Mice, Inbred ICR; Phenobarbital; Phentolamine; Propranolol; Seizures

2000
[Comparative action of products, numbers 3277 R.P., 4560 R.P., 4909 R.P. and of phenobarbital on convulsions induced by strychnine, picrotoxin, cocaine, cafeine and amphetamine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7

    Topics: Amphetamine; Amphetamines; Chlorpromazine; Cocaine; Histamine H1 Antagonists; Phenobarbital; Phenothiazines; Picrotoxin; Seizures; Strychnine

1956
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
    Helvetica physiologica et pharmacologica acta, 1962, Volume: Suppl 12

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental

1962
[PHARMACOLOGICAL STUDIES ON GUANETHIDINE DERIVATIVES. II. EFFECTS OF SOME DRUGS ON HYPOTENSIVE ACTION OF GUANETHIDINE AND (2-(HEXAHYDRO-1-AZEPINYL)ETHYL)GUANIDINE SULFATE].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84

    Topics: Antihypertensive Agents; Blood Pressure; Chloralose; Cocaine; Epinephrine; Guanethidine; Guanidine; Hydrazines; Norepinephrine; Pentobarbital; Pharmacology; Phenobarbital; Rats; Research; Reserpine; Secobarbital; Sympathomimetics; Thiopental; Tyramine; Urethane

1964
[EXPERIMENTAL STUDIES ON THE EFFECT OF SOME PHARMACOLOGICAL PREPARATIONS ON THE ANESTHETIC ACTIVITY OF COCAINE].
    Klinika oczna, 1964, Volume: 34

    Topics: Adjuvants, Anesthesia; Anesthetics; Anura; Caffeine; Chlorpromazine; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Humans; Nitrates; Pentylenetetrazole; Pharmacology; Phenobarbital; Rabbits; Research; Reserpine

1964
Drug analysis in blowfly larvae and in human tissues: a comparative study.
    International journal of legal medicine, 2004, Volume: 118, Issue:4

    Topics: Animals; Antidepressive Agents; Cadaver; Cocaine; Diptera; Feeding Behavior; Forensic Medicine; Humans; Larva; Liver; Narcotics; Phenobarbital; Xenobiotics

2004
Brief postnatal exposure to phenobarbital impairs passive avoidance learning and sensorimotor gating in rats.
    Epilepsy & behavior : E&B, 2014, Volume: 37

    Topics: Animals; Anticonvulsants; Avoidance Learning; Cocaine; Female; Male; Memory; Phenobarbital; Rats; Seizures; Sensory Gating

2014