cocaine has been researched along with paroxetine in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 27 (57.45) | 18.2507 |
| 2000's | 13 (27.66) | 29.6817 |
| 2010's | 7 (14.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goodman, MM; Kabalka, GW; Kung, HF; Kung, MP; Switzer, R | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Abraham, P; Carroll, FI; Cline, EJ; Dannals, RF; Kuhar, MJ; Lewin, AH; Ricaurte, GA; Scheffel, U | 1 |
| Abraham, P; Boja, JW; Carroll, FI; Kopajtic, TA; Kuhar, MJ; Lewin, AH; Mitchell, WM; Patel, A | 1 |
| Akunne, HC; de Costa, BR; Jacobson, AE; Rice, KC; Rothman, RB | 1 |
| Akbari, HM; Azmitia, EC; Kramer, HK; Spear, LP; Whitaker-Azmitia, PM | 1 |
| Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH; Philip, A; Rahman, MA | 1 |
| London, ED; Mantione, CR; Ritz, MC | 1 |
| Alexoff, DA; Chen, R; Dewey, SL; Ding, YS; Fowler, JS; Gatley, SJ; Pan, D | 1 |
| Kelly, PA; McBean, DE; Ritchie, IM; Sharkey, J | 1 |
| Cline, EJ; Kim, S; Kuhar, MJ; Scheffel, U | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD | 1 |
| Campbell, AD; Erwin, VG; Jones, BC; Womer, DE | 1 |
| Cheng, CH; Costall, B; Naylor, RJ; Rudd, JA | 1 |
| Childers, SR; Davies, HM; Kuhn, LA; Matasi, JJ; Sexton, T; Thornley, C | 1 |
| Allard, P; Marcusson, JO; Ross, SB | 1 |
| Abraham, P; Blough, BE; Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH | 1 |
| Abraham, P; Boja, JW; Carroll, FI; Holmquist, CR; Keverline-Frantz, KI; Kuhar, MJ | 1 |
| Abraham, P; Carroll, FI; Kopajtic, T; Kuhar, MJ; Lever, JR; Mathews, WB; Parham, KR; Scheffel, U | 1 |
| Carroll, FI; Holmquist, CR; Kepler, JA; Kuhar, MJ; Saindane, AM; Scheffel, U; Taylor, GF; Zhan, Y | 1 |
| Dannals, RF; Liu, X; Mochizuki, T; Musachio, JL; Scheffel, U; Villemagne, VL; Wagner, HN | 1 |
| Avor, K; Basmadjian, GP; Chan, HM; Hall, N; Seale, TW; Singh, S | 1 |
| Abraham, P; Boja, JW; Burgess, JP; Carroll, FI; Keverline-Frantz, KI; Kuhar, MJ; Lewin, AH | 1 |
| McReynolds, AM; Meyer, JS | 1 |
| Elmer, LW; Little, KY; Zhang, L | 1 |
| Baldwin, RM; Berman, R; Carpenter, L; Charney, DS; Innis, RB; Malison, RT; Nemeroff, CB; Owens, MJ; Pelton, GH; Price, LH; Rajeevan, N; Sanacora, G; Seibyl, JP; van Dyck, CH | 1 |
| McReynolds, AM; Meyer, JS; Shearman, LP; Zhou, FC | 1 |
| Battaglia, G; Carroll, FI; Kuhar, MJ; Vicentic, A | 1 |
| Baldessarini, RJ; Tarazi, FI; Zhang, K | 1 |
| Deslandes, PN; Pache, DM; Sewell, RD; Subhan, F | 1 |
| DeFelice, LJ; Ramsey, IS | 1 |
| Buckland, P; Deslandes, PN; Pache, DM; Sewell, RD | 1 |
| Battaglia, G; Carrasco, GA; Chen, Z; Landry, M; Van de Kar, LD; Waimey, K | 1 |
| Anand, A; Baldwin, RM; Bozkurt, A; Charney, D; Innis, RB; Khan, S; Kugaya, A; Malison, RT; Sanacora, G; Seibyl, JP; Staley, JK; Van Dyck, CH | 1 |
| Battaglia, G; Carrasco, GA; Chen, Z; Muma, NA; Shankaran, M; Sripathirathan, K; Tetzlaff, J; Van De Kar, LD | 1 |
| Daniela, E; Gittings, D; Hely, L; Lake, B; Mash, DC; Schenk, S | 1 |
| Booij, J; Fransen, EJ; Franssen, EJ; Michel, MC; Reitsma, JB; Ruhé, HG; Schene, AH; v Weert, HC | 1 |
| Cheng, FC; Feng, JJ; Lin, CH; Wei, JW; Yang, SD | 1 |
| Abad, S; Camarasa, J; Escubedo, E; Pubill, D; Torres, I | 1 |
| Booij, J; Koster, M; Ruhé, HG; Schene, AH; van Herk, M; Veltman, DJ | 1 |
| Davis, BA; Forrest, LR; Nagarajan, A; Singh, SK | 1 |
| Aungier, J; Cuesta, M; Morton, AJ; Ouk, K | 1 |
3 trial(s) available for cocaine and paroxetine
| Article | Year |
|---|---|
Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography.
Topics: Adult; Antidepressive Agents; Brain; Brain Stem; Carrier Proteins; Cocaine; Depressive Disorder; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Psychiatric Status Rating Scales; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 1998 |
Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
Topics: Adult; Analysis of Variance; Brain Mapping; Cocaine; Depressive Disorder, Major; Diencephalon; Female; Fluoxetine; Humans; Iodine Radioisotopes; Male; Matched-Pair Analysis; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Radiopharmaceuticals; Reference Values; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2004 |
Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antidepressive Agents, Second-Generation; Brain; Cocaine; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Paroxetine; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon; Young Adult | 2009 |
44 other study(ies) available for cocaine and paroxetine
| Article | Year |
|---|---|
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tropanes | 1994 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[123/125I]RTI-55, an in vivo label for the serotonin transporter.
Topics: Animals; Biological Transport, Active; Cocaine; Fenfluramine; Histocytochemistry; Indicators and Reagents; Iodine Radioisotopes; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tomography, Emission-Computed, Single-Photon | 1992 |
High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.
Topics: Animals; Autoradiography; Benztropine; Binding, Competitive; Brain; Carrier Proteins; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tritium | 1992 |
[3H] cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: allosteric modulation by paroxetine.
Topics: Allosteric Regulation; Animals; Binding Sites; Brain; Carrier Proteins; Cell Membrane; Cocaine; Guinea Pigs; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Piperazines; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tritium | 1992 |
Prenatal cocaine exposure disrupts the development of the serotonergic system.
Topics: Animals; Animals, Newborn; Cocaine; Embryonic and Fetal Development; Female; Immunohistochemistry; Maternal-Fetal Exchange; Nerve Fibers; Neurons; Paroxetine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1992 |
Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.
Topics: Animals; Benzamides; Binding, Competitive; Brain Stem; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Thiocyanates | 1991 |
Spermine interacts with cocaine binding sites on dopamine transporters.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Inbred F344; Receptors, Drug; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spermine | 1994 |
Binding of bromine-substituted analogs of methylphenidate to monoamine transporters.
Topics: Animals; Binding, Competitive; Bromine; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Microdialysis; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tomography, Emission-Computed, Single-Photon | 1994 |
Alterations in local cerebral blood flow in mature rats following prenatal exposure to cocaine.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Cocaine; Female; Glucose; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1994 |
Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: in vivo studies with [125I]RTI-55.
Topics: 1-Naphthylamine; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Cocaine; Fluoxetine; Hypothalamus; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sertraline | 1994 |
Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.
Topics: Carrier Proteins; Cells, Cultured; Choriocarcinoma; Cocaine; Female; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Microvilli; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Placenta; Pregnancy; Serotonin; Serotonin Plasma Membrane Transport Proteins; Uterine Neoplasms | 1994 |
Pharmacogenetics of cocaine: II. Mesocorticolimbic and striatal dopamine and cocaine receptors in C57BL and DBA mice.
Topics: Animals; Benzamides; Benzazepines; Binding Sites; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Limbic System; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nerve Tissue Proteins; Paroxetine; Pharmacogenetics; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Drug; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Sulpiride | 1993 |
The effect of 5-HT receptor ligands on the uptake of [3H]5-hydroxytryptamine into rat cortical synaptosomes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cocaine; Desipramine; Female; Fluoxetine; In Vitro Techniques; Indoles; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptosomes; Tropisetron | 1993 |
Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Frontal Lobe; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters; Tropanes | 1996 |
[3H]WIN 35,428 binding in the human brain.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Brain; Cocaine; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Humans; Male; Middle Aged; Paroxetine; Radioligand Assay; Selective Serotonin Reuptake Inhibitors | 1996 |
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine; Nortropanes; Paroxetine; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes | 1996 |
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
Topics: Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Serotonin; Stereoisomerism; Structure-Activity Relationship | 1996 |
N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter.
Topics: Analysis of Variance; Animals; Binding, Competitive; Brain; Carrier Proteins; Cerebellum; Cocaine; Corpus Striatum; Desipramine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Radioligand Assay; Rats; Structure-Activity Relationship; Symporters | 1997 |
RTI-352: a 3 alpha analogue of RTI-55 as an in vivo dopamine transporter binding ligand.
Topics: Animals; Brain; Carrier Proteins; Cocaine; Desipramine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Piperazines; Tritium | 1997 |
A simple probe measures the pharmacokinetics of[125I]RTI-55 in mouse brain in vivo.
Topics: Absorptiometry, Photon; Animals; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Male; Mice; Paroxetine; Piperazines; Radiometry; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Symporters | 1997 |
Synthesis and ligand binding of tropane ring analogues of paroxetine.
Topics: Binding, Competitive; Cocaine; Dopamine Uptake Inhibitors; Isomerism; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Paroxetine; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tropanes | 1998 |
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1998 |
Expression and regulation of the human dopamine transporter in a neuronal cell line.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Enzyme Activation; Gene Expression Regulation, Developmental; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neurons; Paroxetine; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta.
Topics: Animals; Autoradiography; Binding Sites; Carrier Proteins; Cocaine; Female; Immunohistochemistry; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution | 1998 |
Serotonin transporter production and degradation rates: studies with RTI-76.
Topics: Animals; Carrier Proteins; Cerebral Cortex; Cerebral Ventricles; Citalopram; Cocaine; Half-Life; Injections, Intraventricular; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Neurological; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tropanes | 1999 |
Olanzapine, quetiapine, and risperidone: long-term effects on monoamine transporters in rat forebrain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Carrier Proteins; Caudate Nucleus; Cocaine; Dibenzothiazepines; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Olanzapine; Paroxetine; Pirenzepine; Prosencephalon; Putamen; Quetiapine Fumarate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium | 2000 |
Do antidepressants affect motivation in conditioned place preference?
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclobutanes; Cyclohexanols; Dose-Response Relationship, Drug; Fluoxetine; Male; Motivation; Norepinephrine; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sertraline; Venlafaxine Hydrochloride | 2000 |
Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor.
Topics: Amphetamine; Animals; Blotting, Western; Carrier Proteins; Cocaine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Recombinant Proteins; RNA, Complementary; Serotonin; Serotonin Plasma Membrane Transport Proteins; Xenopus laevis | 2002 |
Morphine, cocaine and antidepressant induced motivational activity and midbrain dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mesencephalon; Morphine; Motivation; Nucleus Accumbens; Paroxetine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Sertraline | 2002 |
Prenatal cocaine exposure potentiates paroxetine-induced desensitization of 5-HT2A receptor function in adult male rat offspring.
Topics: Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Drug Synergism; Female; Male; Oxytocin; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists | 2004 |
Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Growth; Oxytocin; Paroxetine; Piperazines; Pregnancy; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Renin; Weight Gain | 2005 |
MDMA self-administration in rats: acquisition, progressive ratio responding and serotonin transporter binding.
Topics: Animals; Autoradiography; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Protein Binding; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tritium | 2007 |
Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [(3)H]8-OH-DPAT and other serotonergic ligands.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Biogenic Amines; Cocaine; Fluoxetine; HeLa Cells; Humans; Kinetics; Ligands; Paroxetine; Radioligand Assay; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Vesicular Biogenic Amine Transport Proteins | 2011 |
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Paroxetine; PC12 Cells; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes | 2011 |
Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder.
Topics: Adult; Amygdala; Cocaine; Depressive Disorder, Major; Dose-Response Relationship, Drug; Facial Expression; Female; Functional Neuroimaging; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2014 |
Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Chickens; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drosophila melanogaster; Drosophila Proteins; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Paroxetine; Protein Conformation; Radioligand Assay; Selective Serotonin Reuptake Inhibitors; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2016 |
Chronic paroxetine treatment prevents disruption of methamphetamine-sensitive circadian oscillator in a transgenic mouse model of Huntington's disease.
Topics: Animals; Central Nervous System Stimulants; Circadian Clocks; Circadian Rhythm; Cocaine; Disease Models, Animal; Female; Huntington Disease; Male; Methamphetamine; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Motor Activity; Paroxetine; Receptors, Dopamine; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Vesicular Monoamine Transport Proteins | 2018 |