cocaine has been researched along with ondansetron in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (44.12) | 18.2507 |
| 2000's | 15 (44.12) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Chebib, M; Johnston, GA | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Emmett-Oglesby, MW; Fagan, K; Hooper, ML; Lane, JD; Pickering, CL; Tyers, MB | 1 |
| van Haaren, F | 1 |
| Lambert, JJ; Malone, HM; Peters, JA | 1 |
| Jasinski, DR; Preston, KL; Sullivan, JT; Testa, M | 1 |
| Peltier, R; Schenk, S | 1 |
| Gifford, AN; Johnson, KM; Yi, SJ | 1 |
| Costall, B; Jones, BJ; Kelly, ME; Naylor, RJ; Onaivi, ES; Tyers, MB | 1 |
| Surprenant, A; Vanner, S | 1 |
| Ellinwood, EH; Joyner, CM; King, GR | 1 |
| Depoortere, RY; Emmett-Oglesby, MW; Lane, JD; Li, DH | 1 |
| Cervo, L; Pozzi, L; Samanin, R | 1 |
| Ellinwood, EH; King, GR; Xiong, Z | 3 |
| Brown, AM; Hope, AG; Lambert, JJ; Peters, JA | 1 |
| Douglass, S; Ellinwood, EH; King, GR; Xiong, Z | 1 |
| Herges, S; Taylor, DA | 1 |
| Davidson, C; Ellinwood, EH; Lee, TH; Xiong, Z | 1 |
| Frys, KA; Kalivas, PW; Szumlinski, KK | 1 |
| De Deurwaerdère, P; Moison, D; Porras, G; Spampinato, U | 1 |
| Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH | 1 |
| Filip, M; Frankowska, M; Göthert, M; Przegaliński, E | 1 |
| Chen, Q; Davidson, C; Ellinwood, EH; Lee, TH; Mi, J; Wetsel, WC; Xiong, X; Zhang, X | 1 |
| Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH; Wetsel, WC; Zhang, X | 1 |
| Chen, Q; Davidson, C; Ellinwood, EH; Lee, TH; Liu, Y; Sun, QA; Wetsel, WC; Xiong, X; Zhang, X | 1 |
| da Silva, FC; de Oliveira Citó, Mdo C; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macêdo, DS; Moura, BA; Silva, MI; Woods, DJ | 1 |
| Ait-Daoud, N; Blevins, D; Johnson, BA; Seneviratne, C; Wang, XQ | 1 |
1 review(s) available for cocaine and ondansetron
| Article | Year |
|---|---|
GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.
Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ion Channels; Ligands; Receptors, GABA; Receptors, GABA-A; Structure-Activity Relationship | 2000 |
1 trial(s) available for cocaine and ondansetron
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled trial of ondansetron for the treatment of cocaine use disorder with post hoc pharmacogenetic analysis.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Humans; Ondansetron; Pharmacogenomic Testing; Treatment Outcome | 2021 |
32 other study(ies) available for cocaine and ondansetron
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Failure of ondansetron to block the discriminative or reinforcing stimulus effects of cocaine in the rat.
Topics: Animals; Arousal; Benzazepines; Brain; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Imidazoles; Motivation; Ondansetron; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Self Administration; Serotonin Antagonists | 1992 |
Effects of cocaine alone and in combination with prazosin or ondansetron on multiple fixed-interval fixed-ratio performance in pigeons.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Drug Interactions; Female; Food; Imidazoles; Male; Ondansetron; Prazosin; Reinforcement Schedule; Serotonin Antagonists | 1992 |
Physiological and pharmacological properties of 5-HT3 receptors--a patch clamp-study.
Topics: Action Potentials; Animals; Cocaine; Ganglia; Guinea Pigs; Imidazoles; Ion Channels; Ketamine; Metoclopramide; Neuroblastoma; Neurons; Ondansetron; Potassium; Rabbits; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sodium; Tubocurarine; Tumor Cells, Cultured | 1991 |
Evaluation of the 5HT3 antagonist ondansetron (O) for cocaine (C)-like activity and abuse potential.
Topics: Cocaine; Humans; Imidazoles; Ondansetron; Substance-Related Disorders | 1990 |
GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Injections, Intravenous; Male; Ondansetron; Rats; Rats, Inbred Strains; Self Administration; Serotonin Antagonists | 1991 |
Effect of cocaine and 5-HT3 receptor antagonists on 5-HT-induced [3H]dopamine release from rat striatal synaptosomes.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dopamine; Female; Imidazoles; Lysergic Acid Diethylamide; Nomifensine; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synaptosomes; Tropanes | 1991 |
Ondansetron inhibits a behavioural consequence of withdrawing from drugs of abuse.
Topics: Animals; Cocaine; Ethanol; Exploratory Behavior; Illicit Drugs; Imidazoles; Male; Mice; Nicotine; Ondansetron; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior; Substance Withdrawal Syndrome | 1990 |
Effects of 5-HT3 receptor antagonists on 5-HT and nicotinic depolarizations in guinea-pig submucosal neurones.
Topics: Acetylcholine; Animals; Cocaine; Curare; Electric Stimulation; Ganglionic Stimulants; Gastric Mucosa; Guinea Pigs; Hexamethonium Compounds; Imidazoles; In Vitro Techniques; Indoles; Iontophoresis; Neuromuscular Depolarizing Agents; Ondansetron; Receptors, Nicotinic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes; Tropisetron | 1990 |
5-HT3 receptor modulation of behavior during withdrawal from continuous or intermittent cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Infusions, Intravenous; Male; Motor Activity; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Substance Withdrawal Syndrome | 1994 |
Parameters of self-administration of cocaine in rats under a progressive-ratio schedule.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Male; Ondansetron; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Reinforcement Schedule; Self Administration | 1993 |
5-HT3 receptor antagonists do not modify cocaine place conditioning or the rise in extracellular dopamine in the nucleus accumbens of rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Indoles; Male; Microdialysis; Nucleus Accumbens; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropanes; Tropisetron | 1996 |
Blockade of cocaine sensitization and tolerance by the co-administration of ondansetron, a 5-HT3 receptor antagonist, and cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Implants; Drug Tolerance; Injections, Subcutaneous; Male; Narcotic Antagonists; Narcotics; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Substance Withdrawal Syndrome | 1997 |
Blockade of the expression of sensitization and tolerance by ondansetron, a 5-HT3 receptor antagonist, administered during withdrawal from intermittent and continuous cocaine.
Topics: Animals; Cocaine; Drug Tolerance; Male; Models, Psychological; Narcotics; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Substance Withdrawal Syndrome | 1998 |
Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).
Topics: Calcium; Cations, Divalent; Cell Line; Cell Membrane Permeability; Cocaine; Electric Conductivity; Evoked Potentials; Humans; Kinetics; Magnesium; Meglumine; Metoclopramide; Models, Chemical; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Recombinant Proteins; Serotonin; Serotonin Antagonists; Sodium; Transfection; Tubocurarine | 1998 |
Blockade of accumbens 5-HT3 receptor down-regulation by ondansetron administered during continuous cocaine administration.
Topics: Analysis of Variance; Animals; Biguanides; Brain; Calcium; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; In Vitro Techniques; Infusion Pumps; Injections, Subcutaneous; Male; Ondansetron; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Long-term blockade of the expression of cocaine sensitization by ondansetron, a 5-HT(3) receptor antagonist.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists | 2000 |
Involvement of 5-HT(3) receptors in the nucleus accumbens in the potentiation of cocaine-induced behaviours in the rat.
Topics: Animals; Behavior, Animal; Cocaine; Drug Synergism; Fluoxetine; Motor Activity; Nucleus Accumbens; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Time Factors | 2000 |
Ondansetron given in the acute withdrawal from a repeated cocaine sensitization dosing regimen reverses the expression of sensitization and inhibits self-administration.
Topics: Acute Disease; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Ondansetron; Rats; Rats, Sprague-Dawley; Reaction Time; Self Administration; Serotonin Antagonists; Substance Withdrawal Syndrome | 2002 |
Pretreatment with serotonin 5-HT(3) receptor antagonists produces no observable blockade of long-term motor sensitization to cocaine in rats.
Topics: Anesthetics, Local; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Fluphenazine; Injections; Male; Motor Activity; Ondansetron; Oxazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropanes | 2003 |
Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electrochemistry; Haloperidol; Male; Microdialysis; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT3 Receptor Antagonists; Tropanes | 2003 |
Ondansetron, given during the acute cocaine withdrawal, attenuates oral cocaine self-administration.
Topics: Administration, Oral; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists; Stereotyped Behavior; Substance Withdrawal Syndrome | 2004 |
WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function.
Topics: Animals; Benzoxazines; Cocaine; Dose-Response Relationship, Drug; Male; Morpholines; Motor Activity; Naphthalenes; Ondansetron; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Rimonabant; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists | 2005 |
PI3 kinase is involved in cocaine behavioral sensitization and its reversal with brain area specificity.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Resistance; Locomotion; Male; Ondansetron; Pergolide; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2006 |
Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors.
Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Therapy, Combination; Glutamic Acid; Male; Neurons; Nucleus Accumbens; Ondansetron; Pergolide; Phosphorylation; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Synaptic Transmission | 2007 |
Reversal of cocaine sensitization-induced behavioral sensitization normalizes GAD67 and GABAA receptor alpha2 subunit expression, and PKC zeta activity.
Topics: Animals; Behavior, Animal; Caudate Nucleus; Cocaine; Glutamate Decarboxylase; Isoenzymes; Male; Nucleus Accumbens; Ondansetron; Pergolide; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotyped Behavior | 2007 |
Reversal of cocaine withdrawal-induced anxiety by ondansetron, buspirone and propranolol.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Cocaine; Male; Motor Activity; Ondansetron; Propranolol; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2012 |