cocaine has been researched along with nomifensine in 80 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (31.25) | 18.7374 |
| 1990's | 36 (45.00) | 18.2507 |
| 2000's | 14 (17.50) | 29.6817 |
| 2010's | 5 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH | 1 |
| Adkins, S; Duval, RA; Foster, JD; Hauck-Newman, A; Kulkarni, SS; Lever, JR; Parnas, ML; Sakrikar, DS; Vaughan, RA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Arunotayanun, W; Dalley, JW; Gibbons, S; Huang, XP; Iversen, L; Roth, BL; Setola, V; Treble, R | 1 |
| Subbaiah, MAM | 1 |
| Doggrell, SA; Woodruff, GN | 1 |
| Algeri, S; Cattabeni, F; Di Giulio, AM; Galli, CL; Groppetti, A; Maggi, A; Ponzio, F | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB | 2 |
| Carroll, FI; De Costa, BR; Grieg, N; Kim, A; Pert, A; Rice, KC; Rothman, RB | 1 |
| Kuczenski, R; Segal, DS | 1 |
| Gifford, AN; Johnson, KM; Yi, SJ | 1 |
| Gale, K; Meloni, R | 1 |
| Baldessarini, RJ; Kula, NS | 1 |
| Rothman, RB | 1 |
| Badia, A; Sallés, J; Vila, E | 1 |
| Boyson, SJ; Cass, WA; Curella, P; Dwoskin, LP; Larson, G; Lin, LH; Peris, J; Yasuda, RP; Zahniser, NR | 1 |
| Kapusta, DR; Robie, NW | 1 |
| Bergman, J; Johnson, SE; Madras, BK; Spealman, RD | 1 |
| Kruk, ZL; Millar, J; Stamford, JA | 1 |
| Bendriem, B; Dewey, SL; Fowler, JS; Gatley, SJ; Hitzemann, R; Logan, J; Macgregor, RR; Schlyer, DJ; Volkow, ND; Wolf, AP | 1 |
| Palmer, RK; Winger, G; Woods, JH | 1 |
| Carboni, E; Di Chiara, G; Imperato, A; Perezzani, L | 1 |
| Cubeddu, LX; Hoffmann, IS; Talmaciu, RK | 1 |
| Arbilla, S; Baud, P; Langer, SZ | 1 |
| Ishida, Y; Kihara, M; Kobayashi, S; Koga, N; Nanbu, T | 1 |
| Byrd, LD; Church, WH; Justice, JB | 1 |
| Castelletti, L; Govoni, S; Hanbauer, I; Missale, C; Spano, PF; Trabucchi, M | 1 |
| Winger, G; Woods, JH | 1 |
| McQuade, PS; Richard, JW; Thakur, M | 1 |
| Bonanno, G; Marchi, M; Maura, G; Raiteri, M | 1 |
| Gianutsos, G; Light, S; Morrow, G; Sweeney, MJ | 1 |
| Cubeddu, LX; Hoffmann, IS; James, MK | 1 |
| Hertting, G; Hoffmann, I; Jackisch, R; Starke, K; Zumstein, A | 1 |
| Cohen, G; Dembiec, D | 1 |
| Kamiya, H; Kohjimoto, Y; Saito, R; Sakurai, Y; Takano, Y | 1 |
| Dóda, M; György, L; Orr, Z | 1 |
| Dembiec, D | 1 |
| de Langen, CD; Mulder, AH | 1 |
| Braakhuis, B; De Regt, V; Dijkstra, D; Horn, AS; Mulder, AH | 1 |
| Garris, PA; Wightman, RM | 1 |
| Garris, PA; Jones, SR; Wightman, RM | 1 |
| Bonnet, JJ; Costentin, J; Héron, C | 1 |
| Kruk, ZL; Wieczorek, WJ | 1 |
| Callaway, CW; Geyer, MA; Paulus, MP | 1 |
| Cabib, S; Castellano, C; Cestari, V; Puglisi-Allegra, S | 1 |
| Bolinao, ML; Moghaddam, B | 1 |
| Brinjak, R; Chrapusta, SJ; Hitri, A; Karoum, F; Wyatt, RJ | 1 |
| Meiergerd, SM; Schenk, JO | 1 |
| Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC | 1 |
| Boja, JW; Brouard, A; Carroll, FI; Kuhar, MJ; Pelaprat, D; Rostene, W; Vial, M | 1 |
| Cass, WA; Flach, KA; Gerhardt, GA; Zahniser, NR | 1 |
| Hirobe, M; Nagao, T; Ohta, S; Ono, H; Tateyama, M; Watanabe, H | 1 |
| Hirobe, M; Nagao, T; Ohta, S; Ono, H; Tateyama, M | 1 |
| Kuzmin, AV; Mantsev, VV; Vislobokov, AI | 1 |
| Jones, SR; Marshall, JF; O'Dell, SJ; Wightman, RM | 1 |
| De Pandis, MF; Margotta, V; Palladini, G; Ruggeri, S; Stocchi, F; Venturini, G | 1 |
| Bernardi, G; Bonci, A; Mercuri, NB; Scarponi, M; Siniscalchi, A | 1 |
| Cadet, JL; Ladenheim, B; Tella, SR | 1 |
| Aspen, JM; Winger, G | 1 |
| Bolanos, CA; Glatt, SJ; Jackson, D | 1 |
| Gerhardt, GA; Hoffman, AF; Lupica, CR | 1 |
| Hashimoto, T; Kajii, Y; Nishikawa, T | 1 |
| Gerhardt, GA; Hebert, MA; Larson, GA; Zahniser, NR | 1 |
| Bernardi, G; Mercuri, NB; Scarponi, M | 1 |
| Wirtshafter, D | 1 |
| Dohi, T; Ikeda, T; Kitayama, S; Morita, K; Sato, T | 1 |
| Davidson, C; Douglas, SB; Ellinwood, EH; Lee, TH | 1 |
| Carroll, FI; Garris, PA; Kuhar, MJ; Reith, ME; Wu, Q | 1 |
| Balu, R; Davidson, C; Ellinwood, EH; Lee, TH | 1 |
| Garris, PA; Kawagoe, KT; Reith, ME; Wightman, RM; Wu, Q | 1 |
| Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF | 1 |
| Nuwayhid, SJ; Werling, LL | 1 |
| Dopheide, MM; Miller, DK; Morgan, RE; Rodvelt, KR; Schachtman, TR | 1 |
| Eshleman, AJ; Janowsky, A; Johnson, RA; Wilhelm, CJ | 1 |
| Canales, JJ; Cardá, M; Ferragud, A; Hernández-Rabaza, V; Merino, V; Murga, J; Nácher, A; Velázquez-Sánchez, C | 1 |
| Borgkvist, A; Feltmann, K; Lindskog, M; Malmlöf, T; Schilström, B | 1 |
| Calipari, ES; Ferris, MJ; Jones, SR; Mateo, Y; Melchior, JR; Roberts, DC | 1 |
| Hoffman, AF; Lupica, CR; Spivak, CE | 1 |
2 review(s) available for cocaine and nomifensine
| Article | Year |
|---|---|
Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.
Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship | 1992 |
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Drug Design; Humans; Selective Serotonin Reuptake Inhibitors | 2018 |
78 other study(ies) available for cocaine and nomifensine
| Article | Year |
|---|---|
Localization of cocaine analog [125I]RTI 82 irreversible binding to transmembrane domain 6 of the dopamine transporter.
Topics: Animals; Azides; Cocaine; Cyanogen Bromide; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epitopes; Humans; Iodine Radioisotopes; Methionine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Trypsin | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.
Topics: Allyl Compounds; HEK293 Cells; Humans; Indoles; Magnetic Resonance Spectroscopy; Molecular Conformation; Propylamines; Protein Binding; Psychotropic Drugs; Receptors, Serotonin; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Tryptamines | 2013 |
Effects of nomifensine on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle.
Topics: Animals; Cocaine; Drug Interactions; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Nomifensine; Norepinephrine; Rats | 1978 |
Significance of dopamine metabolites in the evaluation of drugs acting on dopaminergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Cocaine; Dextroamphetamine; Dopamine; Homovanillic Acid; Male; Methyltyrosines; Neurons; Nomifensine; Pargyline; Rats; Tyramine | 1978 |
Actions of levodopa on rat substantia nigra zona compacta neurons.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cocaine; Female; Levodopa; Male; Neurons; Nomifensine; Rats; Rats, Wistar; Substantia Nigra; Sulpiride | 1992 |
Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter.
Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Nomifensine; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1992 |
Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Homovanillic Acid; Nomifensine; Nucleus Accumbens; Rats | 1992 |
Dopamine uptake inhibition potentiates the effects of L-DOPA on rat substantia nigra zona compacta neurons.
Topics: Action Potentials; Amphetamine; Animals; Biological Transport; Cocaine; Dopamine; Dopamine Antagonists; Drug Synergism; Female; In Vitro Techniques; Levodopa; Male; Neurons; Neurotransmitter Uptake Inhibitors; Nomifensine; Rats; Rats, Inbred Strains; Substantia Nigra; Sulpiride | 1991 |
Effect of cocaine and 5-HT3 receptor antagonists on 5-HT-induced [3H]dopamine release from rat striatal synaptosomes.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dopamine; Female; Imidazoles; Lysergic Acid Diethylamide; Nomifensine; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Synaptosomes; Tropanes | 1991 |
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; Cocaine; Dopamine; Fetal Tissue Transplantation; Fluoxetine; Imipramine; Male; Neural Pathways; Neurotransmitter Uptake Inhibitors; Nomifensine; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Substantia Nigra | 1991 |
Lack of increase in dopamine transporter binding or function in rat brain tissue after treatment with blockers of neuronal uptake of dopamine.
Topics: Animals; Benztropine; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Reference Values | 1991 |
High affinity dopamine reuptake inhibitors as potential cocaine antagonists: a strategy for drug development.
Topics: Benztropine; Bupropion; Cocaine; Dopamine; Drug Evaluation, Preclinical; Humans; Mazindol; Nomifensine; Propiophenones; Substance-Related Disorders | 1990 |
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle Contraction; Muscles; Nomifensine; Normetanephrine; Nortriptyline; Phenylephrine; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine | 1990 |
Persistence of neurochemical changes in dopamine systems after repeated cocaine administration.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Male; Motor Activity; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Stereotyped Behavior | 1990 |
Effects of cocaine and nomifensine on canine renal venous norepinephrine and dopamine content during electrical stimulation of the renal nerves.
Topics: Animals; Cocaine; Dogs; Dopamine; Electric Stimulation; Female; Kidney; Male; Nomifensine; Norepinephrine; Renal Circulation; Vasoconstriction | 1988 |
Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys.
Topics: Animals; Bupropion; Cocaine; Dopamine; Male; Mazindol; Methylphenidate; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Propiophenones; Saimiri; Self Administration | 1989 |
Dissociation of the actions of uptake blockers upon dopamine overflow and uptake in the rat nucleus accumbens: in vivo voltammetric data.
Topics: Animals; Benztropine; Bupropion; Cocaine; Dopamine; Electric Stimulation; Electrochemistry; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Mapping cocaine binding sites in human and baboon brain in vivo.
Topics: Adult; Animals; Brain; Cocaine; Corpus Striatum; Dopamine; Humans; Male; Middle Aged; Nomifensine; Papio; Receptors, Opioid; Tomography, Emission-Computed | 1989 |
Drug-reinforced responding: rapid determination of dose-response functions.
Topics: Animals; Anticonvulsants; Appetitive Behavior; Arousal; Cocaine; Conditioning, Operant; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Ketamine; Macaca mulatta; Male; Motivation; Nomifensine; Phencyclidine; Self Administration | 1989 |
Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats.
Topics: Amphetamines; Animals; Cocaine; Dopamine; Dose-Response Relationship, Drug; Male; Nomifensine; Nucleus Accumbens; Phencyclidine; Rats; Rats, Inbred Strains; Septal Nuclei; Time Factors | 1989 |
Interactions between endogenous dopamine and dopamine agonists at release modulatory receptors: multiple effects of neuronal uptake inhibitors on transmitter release.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Apomorphine; Bromocriptine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Ergolines; Haloperidol; In Vitro Techniques; Methyltyrosines; Neurotransmitter Uptake Inhibitors; Nomifensine; Quinpirole; Rabbits; Receptors, Dopamine; Reserpine | 1986 |
Inhibition of the electrically evoked release of [3H]acetylcholine in rat striatal slices: an experimental model for drugs that enhance dopaminergic neurotransmission.
Topics: Acetylcholine; Amphetamine; Animals; Chlorpromazine; Clozapine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptic Transmission | 1985 |
4-Hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline (PI-OH): a new potentiator of sympathomimetic amines on the rat anococcygeus muscle.
Topics: Animals; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; In Vitro Techniques; Male; Muscles; Nomifensine; Propranolol; Rats; Rats, Inbred Strains; Sympathomimetics | 1988 |
Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine.
Topics: Animals; Benztropine; Cocaine; Corpus Striatum; Dopamine; Extracellular Space; Male; Nomifensine; Rats; Rats, Inbred Strains; Time Factors; Tropanes | 1987 |
Dopamine uptake is differentially regulated in rat striatum and nucleus accumbens.
Topics: Animals; Biological Transport, Active; Cocaine; Corpus Striatum; Dopamine; Kinetics; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sodium | 1985 |
Comparison of fixed-ratio and progressive-ratio schedules of maintenance of stimulant drug-reinforced responding.
Topics: Animals; Cocaine; Isoquinolines; Macaca mulatta; Male; Nomifensine; Psychopharmacology; Reinforcement Schedule; Reward | 1985 |
Some factors affecting striatal 3-methoxytyramine concentrations in the mouse and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Cocaine; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mice; Nalidixic Acid; Naphthyridines; Nomifensine; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?
Topics: Acetylcholine; Animals; Clomipramine; Clonidine; Cocaine; Desipramine; Dopamine; Hemicholinium 3; In Vitro Techniques; Lysergic Acid Diethylamide; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Nomifensine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Serotonin; Synaptosomes | 1984 |
Dopaminergic properties of nomifensine.
Topics: Animals; Apomorphine; Brain; Cocaine; Dopamine; Dose-Response Relationship, Drug; Isoquinolines; Male; Motor Activity; Muridae; Nomifensine; Norepinephrine; Receptors, Dopamine; Synaptic Transmission; Synaptosomes | 1982 |
Frequency-dependent effects of neuronal uptake inhibitors on the autoreceptor-mediated modulation of dopamine and acetylcholine release from the rabbit striatum.
Topics: Acetylcholine; Animals; Apomorphine; Benztropine; Bupropion; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Neurons; Nomifensine; Propiophenones; Rabbits; Sulpiride | 1983 |
Modulation by endogenous dopamine of the release of acetylcholine in the caudate nucleus of the rabbit.
Topics: Acetylcholine; Animals; Apomorphine; Bretylium Tosylate; Caudate Nucleus; Cocaine; Dopamine; Electric Stimulation; Haloperidol; Nomifensine; Potassium; Rabbits | 1980 |
Potassium-induced release of [3H]catecholamine from brain: effects of pre-exposure to catecholamine uptake inhibitors.
Topics: Acetophenones; Animals; Brain Chemistry; Catecholamines; Cocaine; Corpus Striatum; Desipramine; Dopamine; Drug Interactions; Imidazoles; In Vitro Techniques; Male; Mazindol; Nomifensine; Norepinephrine; Occipital Lobe; Potassium; Rats | 1981 |
Effect of imipramine on high potassium evoked 3H-dopamine release in the rat striatum.
Topics: Animals; Calcium; Cocaine; Corpus Striatum; Dopamine; Imipramine; Male; Nomifensine; Potassium; Rats | 1981 |
Influence of dopamine and dopaminergic agonists on relaxation of isolated rabbit ileum induced by sympathetic nerve stimulation.
Topics: Animals; Apomorphine; Bromocriptine; Cocaine; Dopamine; Electric Stimulation; Ileum; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nomifensine; Norepinephrine; Rabbits; Sulpiride; Sympathetic Nervous System; Yohimbine | 1981 |
Inhibition of potassium-stimulated release of [3H]dopamine from rat striata as a result of prior exposure to cocaine, nomifensine, or mazindol.
Topics: Animals; Catecholamines; Cocaine; Corpus Striatum; Dopamine; Male; Mazindol; Nomifensine; Potassium; Rats | 1980 |
Effects of psychotropic drugs on the distribution of 3H-dopamine into compartments of rat striatal synaptosomes and on subsequent depolarization-induced 3H-dopamine release.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; In Vitro Techniques; Nomifensine; Potassium; Psychotropic Drugs; Rats; Reserpine; Synaptosomes; Tyramine | 1980 |
Effects of ADTN and various other 2-aminotetralin derivatives on the efflux of 3H-dopamine from rat striatal slices.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Naphthalenes; Naphthols; Nomifensine; Rats; Receptors, Dopamine; Structure-Activity Relationship; Tetrahydronaphthalenes; Tritium | 1980 |
Distinct pharmacological regulation of evoked dopamine efflux in the amygdala and striatum of the rat in vivo.
Topics: Amygdala; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Electric Stimulation; Electrochemistry; Extracellular Space; Male; Microelectrodes; Neostriatum; Nomifensine; Putamen; Rats; Rats, Sprague-Dawley | 1995 |
Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens.
Topics: Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; In Vitro Techniques; Kinetics; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1995 |
Evidence that pure uptake inhibitors including cocaine interact slowly with the dopamine neuronal carrier.
Topics: Amphetamine; Animals; Binding Sites; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylmaleimide; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Neurons; Nomifensine; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley | 1994 |
A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice.
Topics: Animals; Benztropine; Brain; Caudate Nucleus; Cocaine; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Nomifensine; Nucleus Accumbens; Putamen; Rats; Rats, Wistar; Sulpiride | 1994 |
Quantitative assessment of the microstructure of rat behavior: II. Distinctive effects of dopamine releasers and uptake inhibitors.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dextroamphetamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Motor Activity; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1993 |
Strain-dependent effects of post-training cocaine or nomifensine on memory storage involve both D1 and D2 dopamine receptors.
Topics: Animals; Avoidance Learning; Benzazepines; Cocaine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electroshock; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nomifensine; Receptors, Dopamine D1; Receptors, Dopamine D2; Species Specificity; Sulpiride | 1994 |
Glutamatergic antagonists attenuate ability of dopamine uptake blockers to increase extracellular levels of dopamine: implications for tonic influence of glutamate on dopamine release.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Chloral Hydrate; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Extracellular Space; Glutamic Acid; Microdialysis; Nomifensine; Rats | 1994 |
Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; Male; Methyltyrosines; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 1994 |
Kinetic evaluation of the commonality between the site(s) of action of cocaine and some other structurally similar and dissimilar inhibitors of the striatal transporter for dopamine.
Topics: Animals; Benztropine; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Male; Mazindol; Models, Biological; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley | 1994 |
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1994 |
Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Dopamine; Embryo, Mammalian; Fluoxetine; Iodine Radioisotopes; Kinetics; Mesencephalon; Neurons; Nomifensine; Rats; Rats, Wistar; Stereoisomerism; Tritium | 1993 |
Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: role of metabolism and effects of locally applied uptake inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase; Cocaine; Corpus Striatum; Deoxyepinephrine; Dopamine; Electrochemistry; Kinetics; Male; Microinjections; Nomifensine; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Methamphetamine antagonistic property of (+)- and (-)-4-phenyltetrahydroisoquinoline in rat anococcygeus muscle.
Topics: Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Isoquinolines; Male; Methamphetamine; Methoxamine; Muscle Contraction; Muscles; Nerve Endings; Nomifensine; Norepinephrine; Oxidopamine; Rats; Rats, Wistar; Stereoisomerism; Tetrahydroisoquinolines | 1993 |
4-Phenyltetrahydroisoquinoline, but not nomifensine or cocaine, inhibits methamphetamine-induced dopamine release.
Topics: Animals; Cocaine; Dopamine; Isoquinolines; Male; Methamphetamine; Nomifensine; Nucleus Accumbens; Rats; Rats, Wistar; Tetrahydroisoquinolines | 1993 |
Cocaine, amphetamine and cathinone, but not nomifensine and pargyline increase calcium inward current in internally perfused neurons.
Topics: Alkaloids; Amphetamine; Animals; Calcium; Cocaine; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Techniques; Ion Transport; Lymnaea; Membrane Potentials; Neurons; Nomifensine; Pargyline; Perfusion; Psychotropic Drugs | 1993 |
Functional and anatomical evidence for different dopamine dynamics in the core and shell of the nucleus accumbens in slices of rat brain.
Topics: Animals; Autoradiography; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; Electrochemistry; In Vitro Techniques; Kinetics; Male; Mazindol; Microelectrodes; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1996 |
A pharmacological study of cocaine activity in planaria.
Topics: Amidines; Analysis of Variance; Animals; Biological Evolution; Cocaine; Cyclic AMP; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluorescent Dyes; Microscopy, Fluorescence; Motor Activity; Narcotics; Nomifensine; Planarians; Receptors, Dopamine D1; Receptors, Dopamine D2; Staining and Labeling | 1996 |
Monoamine oxidase inhibition causes a long-term prolongation of the dopamine-induced responses in rat midbrain dopaminergic cells.
Topics: Amphetamine; Animals; Clorgyline; Cocaine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Isoenzymes; Membrane Potentials; Mesencephalon; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Nomifensine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Selegiline; Sulpiride | 1997 |
Differential regulation of dopamine transporter after chronic self-administration of bupropion and nomifensine.
Topics: Animals; Bupropion; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 1997 |
Ethanol effects on self-administration of alfentanil, cocaine, and nomifensine in rhesus monkeys.
Topics: Alfentanil; Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Macaca mulatta; Male; Narcotics; Nomifensine; Self Administration | 1997 |
Subsensitivity to dopaminergic drugs in periadolescent rats: a behavioral and neurochemical analysis.
Topics: Acetylcholine; Aging; Amphetamine; Animals; Apomorphine; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Resistance; Grooming; Habituation, Psychophysiologic; In Vitro Techniques; Male; Motor Activity; Nomifensine; Rats; Rats, Long-Evans; Stereotyped Behavior | 1998 |
Dopamine transporter activity in the substantia nigra and striatum assessed by high-speed chronoamperometric recordings in brain slices.
Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electrochemistry; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Norepinephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Substantia Nigra | 1998 |
Psychotomimetic-induction of tissue plasminogen activator mRNA in corticostriatal neurons in rat brain.
Topics: Animals; Benzazepines; Central Nervous System Agents; Cocaine; Corpus Striatum; Dopamine Antagonists; Haloperidol; In Situ Hybridization; Male; Methamphetamine; Neurons; Nomifensine; Phencyclidine; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Tissue Plasminogen Activator | 1998 |
Age-related reductions in [3H]WIN 35,428 binding to the dopamine transporter in nigrostriatal and mesolimbic brain regions of the fischer 344 rat.
Topics: Age Factors; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred F344; Substantia Nigra; Tritium; Ventral Tegmental Area | 1999 |
Electrophysiological evidence for a reciprocal interaction between amphetamine and cocaine-related drugs on rat midbrain dopaminergic neurons.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Female; Male; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neurons; Nomifensine; Patch-Clamp Techniques; Rats; Rats, Wistar; Reserpine | 1999 |
A comparison of the patterns of striatal Fos-like immunoreactivity induced by various dopamine agonists in rats.
Topics: Amphetamine; Animals; Apomorphine; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine Uptake Inhibitors; Immunohistochemistry; Injections, Intraperitoneal; Male; Nalidixic Acid; Naphthyridines; Nomifensine; Piperazines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Staining and Labeling | 2000 |
Changes in seizure susceptibility to local anesthetics by repeated administration of cocaine and nomifensine but not GBR12935: possible involvement of noradrenergic system.
Topics: Anesthetics, Local; Animals; Cocaine; Male; Mice; Mice, Inbred ICR; Nomifensine; Norepinephrine; Piperazines; Seizures | 2000 |
Effect of cocaine, nomifensine, GBR 12909 and WIN 35428 on carbon fiber microelectrode sensitivity for voltammetric recording of dopamine.
Topics: Animals; Artifacts; Calibration; Carbon; Coated Materials, Biocompatible; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Electrodes, Implanted; Equipment Failure; Fluorocarbon Polymers; Male; Microelectrodes; Nomifensine; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2000 |
Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.
Topics: Animals; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electric Stimulation; Electrochemistry; Electrodes, Implanted; Extracellular Space; Injections, Intraperitoneal; Injections, Intraventricular; Male; Medial Forebrain Bundle; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nomifensine; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tropanes | 2001 |
Differential time-course profiles of dopamine release and uptake changes induced by three dopamine uptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Animals; Benzazepines; Brain Chemistry; Clomipramine; Cocaine; Desipramine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrochemistry; Male; Nomifensine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sulpiride | 2001 |
Determination of release and uptake parameters from electrically evoked dopamine dynamics measured by real-time voltammetry.
Topics: Action Potentials; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electric Stimulation; Electrophysiology; Extracellular Space; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Models, Neurological; Neostriatum; Nerve Tissue Proteins; Nomifensine; Nonlinear Dynamics; Nucleus Accumbens; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2001 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Sigma2 (sigma2) receptors as a target for cocaine action in the rat striatum.
Topics: Animals; Benzylamines; Calcium; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Maleimides; Mesylates; N-Methylaspartate; Nomifensine; Pentazocine; Piperidines; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Sulfonamides; Tritium | 2006 |
Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Male; Modafinil; Nicotine; Nomifensine; Rats; Rats, Sprague-Dawley | 2007 |
Lobeline effects on tonic and methamphetamine-induced dopamine release.
Topics: Amphetamine-Related Disorders; Cell Line; Cocaine; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lobeline; Methamphetamine; Nomifensine; Reserpine; Vesicular Monoamine Transport Proteins | 2008 |
The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward.
Topics: Animals; Benztropine; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression; Male; Mice; Motor Activity; Nomifensine; Proto-Oncogene Proteins c-fos; Reward; Space Perception; Stereotyped Behavior | 2009 |
Dopamine in the hippocampus is cleared by the norepinephrine transporter.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Interactions; Hippocampus; Idazoxan; Male; Microdialysis; Morpholines; Nomifensine; Norepinephrine Plasma Membrane Transport Proteins; Raclopride; Rats; Rats, Wistar; Reboxetine; Sodium Channel Blockers; Tetrodotoxin; Time Factors; Wakefulness | 2012 |
Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate.
Topics: Animals; Bupropion; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Male; Methylphenidate; Nomifensine; Rats; Rats, Sprague-Dawley; Self Administration | 2012 |
Enhanced Dopamine Release by Dopamine Transport Inhibitors Described by a Restricted Diffusion Model and Fast-Scan Cyclic Voltammetry.
Topics: Animals; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electric Stimulation; Electrochemical Techniques; Male; Nomifensine; Rats, Sprague-Dawley | 2016 |