Compounds > cocaine

cocaine and nepicastat

cocaine has been researched along with nepicastat in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gaval-Cruz, M; Javors, MA; Liles, LC; Schroeder, JP; Weinshenker, D1
Cooper, DA; Edwards, GL; Freeman, KG; Gaval-Cruz, M; Holmes, PV; Iuvone, PM; Lyle, MA; Ogbonmwan, YE; Pozdeyev, N; Schank, JR; Schroeder, JP; Weinshenker, D1
Gaval-Cruz, M; Iuvone, PM; Liles, LC; Weinshenker, D1
Bini, V; Devoto, P; Flore, G; Gessa, GL; Saba, P1
Epps, SA; Grice, TW; Schroeder, JP; Weinshenker, D1
DePoy, LM; Manvich, DF; Weinshenker, D1
Cooper, DA; Howell, LL; Kimmel, HL; Manvich, DF; Schmidt, KT; Weinshenker, D1
Antinori, S; Devoto, P; Fattore, L; Fratta, W; Frau, R; Gessa, GL; Saba, P1
Devoto, P; Flore, G; Frau, R; Gessa, GL; Saba, P1

Other Studies

9 other study(ies) available for cocaine and nepicastat

ArticleYear
Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: Alcohol Deterrents; Animals; Cocaine; Disulfiram; Dopamine beta-Hydroxylase; Drug Synergism; Enzyme Inhibitors; Female; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Seizures; Thiones

2008
Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:12

    Topics: Alcohol Deterrents; Animals; Brain; Cocaine; Conditioning, Operant; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Drug Interactions; Extinction, Psychological; Food; Imidazoles; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Self Administration; Thiones

2010
Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Cocaine; Disulfiram; Dopamine beta-Hydroxylase; Female; Imidazoles; Locomotion; Male; Mice; Mice, Knockout; Thiones

2012
The dopamine beta-hydroxylase inhibitor nepicastat increases dopamine release and potentiates psychostimulant-induced dopamine release in the prefrontal cortex.
    Addiction biology, 2014, Volume: 19, Issue:4

    Topics: Amphetamine; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Synergism; Imidazoles; Male; Microdialysis; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Thiones

2014
The selective dopamine β-hydroxylase inhibitor nepicastat attenuates multiple aspects of cocaine-seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:6

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine beta-Hydroxylase; Imidazoles; Male; Motor Activity; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Thiones

2013
Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 347, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Disulfiram; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Imidazoles; Male; Morpholines; Rats; Rats, Sprague-Dawley; Reboxetine; Thiones

2013
Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:1

    Topics: Animals; Autonomic Nervous System Diseases; Behavior, Addictive; Cocaine; Conditioning, Operant; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Extinction, Psychological; Imidazoles; Male; Norepinephrine; Nucleus Accumbens; Rats; Saimiri; Self Administration; Thiones

2014
Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation.
    Addiction biology, 2016, Volume: 21, Issue:1

    Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Imidazoles; Levodopa; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Self Administration; Thiones

2016
Selective inhibition of dopamine-beta-hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex.
    Brain and behavior, 2015, Volume: 5, Issue:10

    Topics: Adrenergic Neurons; Animals; Cocaine; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Imidazoles; Injections, Intraventricular; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Self Administration; Thiones

2015