cocaine has been researched along with nalmefene in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Litten, RZ | 1 |
| Bühler, KM; Calleja-Conde, J; Echeverry-Alzate, V; Giné, E; Gual, A; López-Moreno, JA; Maldonado, R; Nadal, R; Rodríguez de Fonseca, F | 1 |
| Kreek, MJ; Reed, B; Windisch, KA | 1 |
| Kreek, MJ; Morochnik, M; Reed, B; Windisch, KA | 1 |
6 other study(ies) available for cocaine and nalmefene
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
International update: new findings on promising medications.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Clinical Trials as Topic; Cocaine; Comorbidity; Europe; Humans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Taurine; United States | 1996 |
Nalmefene is effective at reducing alcohol seeking, treating alcohol-cocaine interactions and reducing alcohol-induced histone deacetylases gene expression in blood.
Topics: Alcohol Drinking; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Gene Expression Regulation, Enzymologic; Histone Deacetylases; Male; Naltrexone; Rats; Rats, Wistar; Structure-Activity Relationship | 2016 |
Naltrexone and nalmefene attenuate cocaine place preference in male mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Opioid; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists | 2018 |
Nalmefene, a mu opioid receptor antagonist/kappa opioid receptor partial agonist, potentiates cocaine motivation but not intake with extended access self-administration in adult male mice.
Topics: Analgesics, Opioid; Animals; Cocaine; Male; Mice; Mice, Inbred C57BL; Motivation; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration | 2021 |