cocaine and nalbuphine

cocaine has been researched along with nalbuphine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's3 (20.00)18.2507
2000's10 (66.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Kornetsky, C1
Drieze, J; Kamien, JB; Lukas, SE; Mello, NK; Mendelson, JH1
Hursh, SR; Winger, G1
France, CP; Gerak, LR1
Brandt, MR; France, CP; Galici, R1
Gerrits, MA; Kuzmin, AV; van Ree, JM; Zvartau, EE1
Winger, G; Woods, JH1
Mello, NK; Negus, SS1
Rodefer, JS; Rowlett, JK; Spealman, RD2
Goletiani, N; Jaszyna-Gasior, M; Mello, NK; Mendelson, JH; Sholar, MB; Siegel, AJ1
Goletiani, NV; Mello, NK; Mendelson, JH; Sholar, MB; Siegel, AJ1
Cole, KT; Iordanou, JC; Kerns, DC; Newsom, PC; Peitz, GW; Schmidt, KT; Smith, MA1

Trials

2 trial(s) available for cocaine and nalbuphine

ArticleYear
Effects of the mixed mu/kappa opioid nalbuphine on cocaine-induced changes in subjective and cardiovascular responses in men.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:3

    Topics: Analgesics, Opioid; Analysis of Variance; Blood Pressure; Cocaine; Diastole; Drug Interactions; Heart Rate; Humans; Male; Nalbuphine; Receptors, Opioid, kappa; Receptors, Opioid, mu; Systole

2005
Opioid and cocaine combined effect on cocaine-induced changes in HPA and HPG axes hormones in men.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Analgesics, Opioid; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Gonadal Steroid Hormones; Gonads; Hormones; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Nalbuphine; Narcotic Antagonists; Testosterone; Young Adult

2009

Other Studies

13 other study(ies) available for cocaine and nalbuphine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Brain-stimulation reward: a model for the neuronal bases for drug-induced euphoria.
    NIDA research monograph, 1985, Volume: 62

    Topics: Animals; Brain; Cocaine; Dextroamphetamine; Electric Stimulation; Euphoria; Humans; Models, Neurological; Morphine; Nalbuphine; Neural Pathways; Neurons; Rats; Reward; Self Stimulation; Substance-Related Disorders; Tripelennamine

1985
The effects of nalbuphine and butorphanol treatment on cocaine and food self-administration by rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1993, Volume: 8, Issue:1

    Topics: Analysis of Variance; Animals; Butorphanol; Cocaine; Conditioning, Operant; Feeding Behavior; Female; Macaca mulatta; Male; Nalbuphine; Receptors, Opioid; Self Administration; Substance-Related Disorders

1993
Normalized demand for drugs and other reinforcers.
    Journal of the experimental analysis of behavior, 1995, Volume: 64, Issue:3

    Topics: Alfentanil; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Macaca mulatta; Methohexital; Nalbuphine; Phencyclidine; Reinforcement, Psychology; Self Administration

1995
Discriminative stimulus effects of nalbuphine in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2

    Topics: Analgesics, Opioid; Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Female; Macaca mulatta; Male; Nalbuphine; Naltrexone

1996
The discriminative stimulus effects of morphine in pigeons responding under a progressive ratio schedule of food presentation.
    Behavioural pharmacology, 2000, Volume: 11, Issue:1

    Topics: Animals; Buprenorphine; Cocaine; Columbidae; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Food; Morphine; Nalbuphine; Narcotic Antagonists; Narcotics; Reinforcement Schedule; Time Factors

2000
Influence of buprenorphine, butorphanol and nalbuphine on the initiation of intravenous cocaine self-administration in drug naive mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:6

    Topics: Analysis of Variance; Animals; Buprenorphine; Butorphanol; Cocaine; Dose-Response Relationship, Drug; Infusions, Intravenous; Male; Mice; Mice, Inbred DBA; Motor Activity; Nalbuphine; Narcotic Antagonists; Self Administration

2000
The effects of chronic morphine on behavior reinforced by several opioids or by cocaine in rhesus monkeys.
    Drug and alcohol dependence, 2001, May-01, Volume: 62, Issue:3

    Topics: Alfentanil; Analgesics, Opioid; Animals; Buprenorphine; Cocaine; Dopamine Uptake Inhibitors; Drug Tolerance; Heroin; Macaca mulatta; Male; Morphine; Nalbuphine; Reaction Time; Reinforcement, Psychology

2001
Effects of mu-opioid agonists on cocaine- and food-maintained responding and cocaine discrimination in rhesus monkeys: role of mu-agonist efficacy.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Analgesics, Opioid; Animals; Butorphanol; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Food; Macaca mulatta; Nalbuphine; Narcotic Antagonists; Receptors, Opioid, mu; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2002
Self-administration of cocaine, alfentanil, and nalbuphine under progressive-ratio schedules: consumer demand and labor supply analyses of relative reinforcing effectiveness.
    Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:4

    Topics: Alfentanil; Animals; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intravenous; Macaca; Male; Nalbuphine; Narcotics; Reaction Time; Reinforcement Schedule; Self Administration

2002
Self-Administration of cocaine-opioid combinations by rhesus monkeys: evaluation of the role of mu receptor efficacy using labor supply analysis.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Alfentanil; Animals; Behavior, Animal; Cocaine; Female; Heroin; Macaca mulatta; Male; Models, Economic; Nalbuphine; Narcotics; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration

2005
The mu/kappa agonist nalbuphine attenuates sensitization to the behavioral effects of cocaine.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Drug Tolerance; Male; Motor Activity; Nalbuphine; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration

2013