cocaine and n-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane

cocaine has been researched along with n-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's9 (37.50)29.6817
2010's9 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Byon, C; Elmaleh, DR; Fischman, AJ; Hanson, RN; Liang, AY; Madras, BK; Meltzer, PC; Shoup, TM1
Babich, JW; Barrow, SA; Elmaleh, DR; Fischman, AJ; Hanson, RN; Madras, BK; Meltzer, P1
Babich, J; Elmaleh, DR; Fischman, AJ; Liang, AY; Madras, BK; Meltzer, PC1
Elmaleh, DR; Fischman, AJ; Gracz, LM; Kaufman, MJ; Liang, AY; Madras, BK; Meltzer, PC1
Babich, J; Elmaleh, D; Fahey, MA; Fischman, AJ; Gracz, LM; Liang, AY; Madras, BK; Meltzer, PC; Stopa, EG1
Alpert, NM; Babich, JW; Barrow, SA; Bonab, AA; Callahan, RJ; Elmaleh, DR; Fischman, AJ; Graham, W; Hanson, RN; Madras, BK; Meltzer, PC; Palmer, EP1
Catz, P; Green, CE; Hettiarachchi, K; Ridge, S; Salem, MA; Wu, B1
Alpert, NM; Babich, JW; Bonab, AA; Fischman, AJ; Livni, E; Madras, BK; Meltzer, PC1
Ward, J1
Cattabeni, F1
Biederman, J; Bonab, AA; Dougherty, DD; Faraone, SV; Fischman, AJ; Madras, BK; Spencer, TJ1
Anderson, CM; Bendor, JT; Fischman, AJ; Frederick, Bd; Kaufman, MJ; Livni, E; Lukas, SE; Maas, LC; Madras, BK; Renshaw, PF; Spencer, TJ1
Biederman, J; Bonab, AA; Ciccone, PE; Dougherty, DD; Fischman, AJ; Livni, E; Madras, BK; Parasrampuria, DA; Spencer, TJ1
Biederman, J; Bonab, AA; Dougherty, DD; Fischman, AJ; Livni, E; Madras, BK; Martin, J; Meltzer, PC; Rauch, S; Spencer, TJ1
Bonab, AA; Clarke, A; Dougherty, DD; Fischman, AJ; Madras, BK; Martin, J; Mirto, T; Spencer, TJ1
Doering, LC; Farncombe, TH; Gleave, JA; Saab, C1
Bonab, AA; Clarke, A; Dougherty, DD; Fischman, AJ; Martin, J; Mirto, T; Spencer, TJ1
Alpert, NM; Becker, JA; El Fakhri, G; Fang, YH1
Batchelder, H; Biederman, J; Bonab, AA; Clarke, A; Dougherty, DD; Faraone, SV; Fischman, AJ; Madras, BK; Spencer, TJ1
Buckner, RL; Hedden, T; Johnson, KA; Rieckmann, A; Sperling, RA; Younger, AP1
Bayer, S; Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M1
Alpert, N; Beltzer, M; Berretta, S; Boyer-Boiteau, A; El Fakhri, G; Goer, F; Kumar, P; Mechawar, N; Murray, L; Normandin, M; Pilobello, KT; Pizzagalli, DA; Turecki, G; Vitaliano, G; Wooten, D1
Clement, N; Frosch, M; Gomez-Isla, T; Gomperts, SN; Growdon, JH; Johnson, KA; Katz, S; Schultz, A; Shirvan, J; Ye, R1

Reviews

3 review(s) available for cocaine and n-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Altropane. O 587.
    Drugs in R&D, 2002, Volume: 3, Issue:3

    Topics: Clinical Trials as Topic; Cocaine; Drug Industry; Humans; Parkinson Disease; Tomography, Emission-Computed, Single-Photon

2002
Altropane (Boston Life Science).
    Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:11

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Cocaine; Humans; Parkinson Disease; Radiopharmaceuticals; Technology, Pharmaceutical; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

2002
In vivo neuroreceptor imaging in attention-deficit/hyperactivity disorder: a focus on the dopamine transporter.
    Biological psychiatry, 2005, Jun-01, Volume: 57, Issue:11

    Topics: Age Factors; Animals; Attention Deficit Disorder with Hyperactivity; Brain Mapping; Carbon Isotopes; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Sensory Receptor Cells; Time Factors; Tomography, Emission-Computed

2005

Trials

5 trial(s) available for cocaine and n-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Rapid detection of Parkinson's disease by SPECT with altropane: a selective ligand for dopamine transporters.
    Synapse (New York, N.Y.), 1998, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Brain; Brain Chemistry; Carrier Proteins; Child; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Receptors, Dopamine D1; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1998
Cerebellar vermis involvement in cocaine-related behaviors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:6

    Topics: Adult; Aged; Autoradiography; Brain Mapping; Carbon Isotopes; Cerebellum; Cocaine; Cocaine-Related Disorders; Female; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Magnetic Resonance Imaging; Male; Oxygen; Positron-Emission Tomography; Postmortem Changes

2006
PET study examining pharmacokinetics, detection and likeability, and dopamine transporter receptor occupancy of short- and long-acting oral methylphenidate.
    The American journal of psychiatry, 2006, Volume: 163, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Behavior, Addictive; Brain; Cocaine; Corpus Striatum; Delayed-Action Preparations; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Humans; Male; Methylphenidate; Middle Aged; Osmosis; Positron-Emission Tomography; Substance Abuse Detection

2006
A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride.
    Biological psychiatry, 2010, Nov-15, Volume: 68, Issue:10

    Topics: Adolescent; Adult; Benzhydryl Compounds; Carbon Radioisotopes; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Modafinil; Positron-Emission Tomography; Raclopride; Radioligand Assay

2010
Understanding the central pharmacokinetics of spheroidal oral drug absorption system (SODAS) dexmethylphenidate: a positron emission tomography study of dopamine transporter receptor occupancy measured with C-11 altropane.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Brain; Carbon Radioisotopes; Cocaine; Delayed-Action Preparations; Dexmethylphenidate Hydrochloride; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Male; Methylphenidate; Middle Aged; Positron-Emission Tomography; Radioligand Assay

2012

Other Studies

16 other study(ies) available for cocaine and n-iodoallyl-2-carbomethoxy-3-(4-fluorophenyl)tropane

ArticleYear
Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:7

    Topics: Animals; Autoradiography; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Saimiri; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon

1996
SPECT imaging of dopamine transporter sites in normal and MPTP-Treated rhesus monkeys.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding Sites; Carrier Proteins; Cocaine; Contrast Media; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Macaca mulatta; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nortropanes; Parkinson Disease; Parkinson Disease, Secondary; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1997
Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain.
    Synapse (New York, N.Y.), 1998, Volume: 29, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Iodine Radioisotopes; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1998
Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain.
    Synapse (New York, N.Y.), 1998, Volume: 29, Issue:2

    Topics: Animals; Autoradiography; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Receptors, Dopamine D1; Saimiri; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1998
Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain.
    Synapse (New York, N.Y.), 1998, Volume: 29, Issue:2

    Topics: Aged; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Putamen; Radioligand Assay; Receptors, Dopamine D1; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1998
Analysis of 2beta-carbomethoxy-3beta-(4-fluorophenyl)-N-(3-iodo-E-allyl)nortropane in rat plasma. I. Method development and validation by capillary electrophoresis.
    Journal of chromatography. A, 2000, Oct-20, Volume: 895, Issue:1-2

    Topics: Animals; Cocaine; Electrophoresis, Capillary; Radiopharmaceuticals; Rats; Reference Standards; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2000
[(11)C, (127)I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites.
    Synapse (New York, N.Y.), 2001, Mar-15, Volume: 39, Issue:4

    Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Ligands; Macaca mulatta; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Sensitivity and Specificity; Tomography, Emission-Computed

2001
New radiopharmaceutical may settle ADHD treatment debate.
    Advance for nurse practitioners, 2001, Volume: 9, Issue:2

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Biological Psychiatry; Child; Cocaine; Gamma Cameras; Humans; Radiopharmaceuticals; Receptors, Dopamine

2001
Further evidence of dopamine transporter dysregulation in ADHD: a controlled PET imaging study using altropane.
    Biological psychiatry, 2007, Nov-01, Volume: 62, Issue:9

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Chi-Square Distribution; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Positron-Emission Tomography

2007
Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:5

    Topics: Animals; Behavior, Animal; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Neostriatum; Neural Stem Cells; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Tomography, Emission-Computed, Single-Photon

2011
Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET.
    NeuroImage, 2012, May-15, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Algorithms; Bayes Theorem; Bias; Carbon Radioisotopes; Cocaine; Data Interpretation, Statistical; Female; Humans; Image Processing, Computer-Assisted; Kinetics; Least-Squares Analysis; Male; Middle Aged; Neuroimaging; Nonlinear Dynamics; Normal Distribution; Population; Positron-Emission Tomography; Radiopharmaceuticals; Reference Values; Sample Size; Young Adult

2012
Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects.
    Biological psychiatry, 2013, Jul-15, Volume: 74, Issue:2

    Topics: 3' Untranslated Regions; Adolescent; Adult; Alleles; Attention Deficit Disorder with Hyperactivity; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Genomics; Humans; Male; Middle Aged; Minisatellite Repeats; Polymorphism, Genetic; Radionuclide Imaging; Risk Factors; Young Adult

2013
Dopamine transporter availability in clinically normal aging is associated with individual differences in white matter integrity.
    Human brain mapping, 2016, Volume: 37, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Aniline Compounds; Benzothiazoles; Blood Pressure; Brain; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Magnetic Resonance Imaging; Male; Multimodal Imaging; Organ Size; Positron-Emission Tomography; Radiopharmaceuticals; Regression Analysis; Thiazoles; White Matter

2016
PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.
    Neuro-degenerative diseases, 2016, Volume: 16, Issue:1-2

    Topics: Alzheimer Disease; Aniline Compounds; Brain; Carbolines; Cocaine; Cognitive Dysfunction; Cross-Sectional Studies; Diagnosis, Differential; Lewy Body Disease; Magnetic Resonance Imaging; Neuropsychological Tests; Parkinson Disease; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Survival Analysis; Thiazoles

2016
Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence.
    JAMA psychiatry, 2019, 08-01, Volume: 76, Issue:8

    Topics: Adult; Autopsy; Carbon Radioisotopes; Cocaine; Cross-Sectional Studies; Depressive Disorder, Major; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Neostriatum; Positron-Emission Tomography; Recurrence; Tissue Banks; Young Adult

2019
Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease.
    Neurology, 2019, 07-30, Volume: 93, Issue:5

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Aniline Compounds; Autopsy; Brain; Cocaine; Contrast Media; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Lewy Body Disease; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Thiazoles

2019