cocaine has been researched along with morphine in 886 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 260 (29.35) | 18.7374 |
| 1990's | 211 (23.81) | 18.2507 |
| 2000's | 223 (25.17) | 29.6817 |
| 2010's | 160 (18.06) | 24.3611 |
| 2020's | 32 (3.61) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Jacobson, AE; Klee, WA; Rice, KC; Shiotani, S | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bonnardot, JP; Bonvoisin, R; Brulé, M; Charron, R; Deligné, P; Tavernier, M | 1 |
| Ellinwood, EH; Kilbey, MM | 1 |
| Ajemian, I; Mount, BM; Scott, JF | 1 |
| Melzack, R; Mount, BM; Ofiesh, JG | 1 |
| Davis, AJ | 1 |
| Tepper, P; Woods, JH | 1 |
| Bonese, K; Killian, A; Rothberg, RM; Schuster, CR; Wainer, BH | 1 |
| Tessel, RE; Tyler, TD | 1 |
| Goldberg, SR; Kelleher, RT; Spealman, RD | 1 |
| Boissier, JR; Simon, P; Soubrié, P | 1 |
| Shuster, L; Webster, GW; Yu, G | 2 |
| Ali, B; Auyong, TK; Parmar, SS; Spencer, HW | 2 |
| Tanner, JA | 1 |
| Miaskowski, C | 1 |
| Castro, A; Malkus, H | 1 |
| Rastogi, RB; Singhal, RL | 1 |
| Gordon, JM; Melzack, R; Mount, BM | 1 |
| Bates, A; Shuster, L; Yu, G | 1 |
| Stretch, R | 1 |
| Sanchez-Ramos, JR; Schuster, CR | 1 |
| Esposito, RU; Jacobson, JO; Kornetsky, C; McLean, S | 1 |
| Governo, TF; Harrington, SM; Prager, MJ | 1 |
| Bürgi, H; Selz, B | 1 |
| Esposito, RU; Kornetsky, C | 1 |
| Hamilton, HE; Harris, SC; Wallace, JE | 1 |
| Twycross, R | 1 |
| Fowler, SC; Leberer, MR | 1 |
| Cravey, RH; Garriott, JC; Lundberg, GD; Reynolds, PC; Shaw, RF | 1 |
| Blumberg, H; Ikeda, C | 1 |
| Martz, G | 1 |
| Castro, A; Mittleman, R | 1 |
| Hirabayashi, M; Iizuka, M; Tadokoro, S | 1 |
| Bertulli, G; Mosca, L; Pedroni, G | 1 |
| Kelleher, RT | 1 |
| Goldberg, DM; Goldberg, SR; Morse, WH | 1 |
| Hosoya, E; Oka, T | 1 |
| Guerrant, GO; Hall, CT | 1 |
| Cuparencu, B; Sandor, V | 1 |
| Leander, JD; Lucot, JB | 1 |
| Ayhan, H; Papeschi, R; Theiss, P | 1 |
| Knapp, S; Mandell, AJ | 3 |
| Austin, DL; Caddy, GR; Gottheil, E | 1 |
| Oksenkryg, GF | 1 |
| Hill, SY; Powell, BJ | 1 |
| Goldenberg, GJ | 2 |
| Pickens, R; Thompson, T | 1 |
| Banford, TA; Cordova, VF | 1 |
| Borisenko, SA; Burov, IuV | 1 |
| Murgia, E; Walton, HF | 1 |
| Reuland, DJ; Trinler, WA | 1 |
| Tgashira, E; Yanaura, S | 1 |
| Jensen, P; Wilkinson, DR; Winsley, D | 1 |
| Kornetsky, C; Porrino, LJ | 1 |
| Martinez, F; Poet, TS; Watson, RR | 2 |
| Billings, B; Candido, J; Duttaroy, A; Lutfy, K; Sierra, V; Yoburn, BC; Zito, SW | 1 |
| Beitner-Johnson, D; Guitart, X; Nestler, EJ | 3 |
| Beitner-Johnson, D; Guitart, X; Kosten, TA; Marby, DW; Nestler, EJ | 1 |
| Doty, P; Dykstra, LA; Johnson, AB; Picker, MJ | 1 |
| Gessa, GL; Hmaidan, Y; Rossetti, ZL | 1 |
| Kauppila, T; Mecke, E; Pertovaara, A | 1 |
| Kuribara, H; Tadokoro, S; Uchihashi, Y | 1 |
| Balabanova, S; Boschek, HJ; Hermann, B; Scheitler, H; Schneider, E; Wepler, R | 1 |
| Adger, H; Duggan, AK; Joffe, A; Kokotailo, PK; Repke, J | 1 |
| Fratta, W; Gessa, GL; Kuzmin, A; Martellotta, MC; Zvartau, E | 1 |
| Watson, RR | 1 |
| Fischman, MW; Foltin, RW | 1 |
| Albertson, TE; Derlet, RW; Tharratt, RS; Tseng, CC | 1 |
| Carboni, S; Gessa, GL; Melis, F; Rossetti, ZL | 1 |
| Curcuruto, O; Guidugli, F; Marigo, M; Sturaro, A; Tagliaro, F; Traldi, P | 1 |
| Goldberg, SR; Grayson, NA; Jaffe, JH; Johnson, RE; Katz, JL; Rice, KC; Witkin, JM | 1 |
| Beitner-Johnson, D; Crain, SM; Nestler, EJ; Sevarino, KA; Terwilliger, RZ | 1 |
| Beitner-Johnson, D; Nestler, EJ | 1 |
| Cory-Slechta, DA; Widzowski, DV | 1 |
| Chen, GJ; Watson, RR | 1 |
| Brady, M; Gause, S; Ostrea, EM; Raymundo, AL; Stevens, M | 1 |
| Ammann, H; Vinet, B | 1 |
| Dworkin, SI; Porrino, LJ; Smith, JE | 1 |
| Chiba, S; Nishida, N | 1 |
| Carney, JM; Cheng, MS; Landrum, RW; Seale, TW | 1 |
| Gjerde, H; Mørland, J | 1 |
| Chau, F; Desforges, B; Lechat, P; Pocidalo, JJ; Rouveix, B; Sinet, M; Starec, M | 1 |
| Chen, GJ; Huang, DS; Lopez, MC; Watson, RR; Watzl, B | 1 |
| Bokos, P; Donahoe, RM; Falek, A; Gallegos, K; Madden, JJ; Nicholson, JK; Veit, R | 1 |
| Sastry, BV | 1 |
| Evans, EB; Wenger, GR | 1 |
| Burnett, D; Richens, A; Smith, BL; Toseland, PA; Walker, G; Williams, J; Wilson, JF | 1 |
| Garriott, JC | 1 |
| Huston-Lyons, D; Kornetsky, C; Porrino, LJ | 1 |
| Kuribara, H; Tadokoro, S | 1 |
| Asami, T; Ida, I; Kuribara, H; Machiyama, Y; Tadokoro, S | 1 |
| Cai, B; Matsumoto, K; Nakamura, S; Watanabe, H | 1 |
| Martinez, F; Watson, RR | 1 |
| Wenger, GR; Wright, DW | 1 |
| Brodin, P; Skoglund, LA | 1 |
| Mohs, ME; Watson, RR | 1 |
| Ash, KO; Pearson, SD; Urry, FM | 1 |
| Lett, BT | 1 |
| Amass, L; Benedikt, R; Lukas, SE; Mendelson, JH | 1 |
| Needleman, SB; Romberg, RW | 1 |
| Asensio, DC; Brady, MJ; Naluz, A; Ostrea, EM; Parks, PM | 1 |
| Asami, T; Kuribara, H | 1 |
| Misra, AL; Pontani, RB; Vadlamani, NL | 1 |
| Brendel, K; Conners, S; Krumdieck, CL; Rankin, DR | 1 |
| Klöppel, A; Weiler, G | 1 |
| Mackey, WB; van der Kooy, D | 1 |
| Sieghart, W | 1 |
| Baud, FJ; Diamant-Berger, O; Dupeyron, JP; Gherardi, RK; Leporc, P; Marc, B | 1 |
| Boone, DJ; Caudill, SP; Hansen, HJ | 1 |
| Chiang, CN; Lee, CC | 1 |
| Järbe, TU; Swedberg, MD | 2 |
| Shimada, A; Tsuda, T; Yanagita, T | 1 |
| Hori, A; Kaneto, H | 1 |
| Canel, AM; Foley, KM; Houde, RW; Kaiko, RF; Kanner, R; Rogers, AG; Wallenstein, SL | 1 |
| Duffy, P; Kalivas, PW | 1 |
| Inturrisi, CE; Yoburn, BC | 1 |
| Hijikuro, K; Kaneto, H | 1 |
| Broussolle, EP; Fanelli, RJ; Jaffe, JH; London, ED; Weissman, AD; Wilkerson, G | 1 |
| Das, NP; Ratty, AK | 1 |
| Paule, MG; Wenger, GR | 1 |
| Brettell, TA; Saferstein, R | 1 |
| Kornetsky, C | 1 |
| Emmett-Oglesby, MW; Wood, DM | 1 |
| Gorodetzky, CW | 1 |
| Perry, RH; Weller, M | 1 |
| Bastos, ML; Jukofsky, D; Mulé, SJ | 1 |
| Bennett, A; Stockley, HL | 1 |
| Elliott, HW; Hine, CH; Nomof, N; Parker, KD | 1 |
| Bewley, T | 1 |
| Doetsch, RN; Smith, JL | 1 |
| Berger, H | 1 |
| Schuster, CR; Wilson, MC | 1 |
| Goldberg, SR; Hoffmeister, F | 1 |
| Hoffmeister, F; Wuttke, W | 1 |
| Westfall, TC | 1 |
| Hoffmeister, F; Kroneberg, G; Oberdorf, A; Wirth, W | 1 |
| Goldberg, SR; Hoffmeister, F; Schlichting, U; Wuttke, W | 1 |
| Takemori, AE; Wang, JH | 1 |
| Trendelenburg, U | 1 |
| Paton, WD; Zar, MA | 1 |
| Goldenberg, MM | 3 |
| Marlow, HF | 1 |
| Peterson, GR; Shuster, L; Werner, I | 1 |
| Gascon, AL; Pérès, MT | 1 |
| Bastiani, RJ; Phillips, RC; Schneider, RS; Ullman, EF | 1 |
| Park, WK; Regoli, D; Rioux, F | 1 |
| Leute, R | 1 |
| Conine, F; Paul, J | 1 |
| Benfey, BG; Cohen, J; Kunos, G; Vermes-Kunos, I | 1 |
| Hadidian, Z; Ilievski, V; Smith, ER | 1 |
| Bennett, A | 1 |
| Mennear, JH; Rudzik, AD | 1 |
| Akubue, PI | 1 |
| Dhalla, NS | 1 |
| Baird, KM; Rixon, RH | 1 |
| Kato, R; Onoda, K; Takayanagi, M | 1 |
| Afrikanov, II; Vedernikov, YP | 1 |
| Saarnivaara, L | 1 |
| Dyer, DC | 1 |
| Ishida, Y; Moritoki, H | 1 |
| Vedernikov, YP | 1 |
| Krstić, MK | 3 |
| Saxena, PR | 1 |
| Aihara, H; Kasai, A; Sakai, T | 1 |
| Sapeika, N; Zwarenstein, H | 1 |
| Higgins, TN; Taylor, JD | 1 |
| Harwood, CT | 1 |
| Dubileĭ, PV; Urazaeva, ZV | 1 |
| Price, KR | 1 |
| Henriksson, BG; Järbe, TU | 1 |
| Farag, AA; Ghonemy, AM; Wagih, IM | 1 |
| Bonese, KF; Fitch, FW; Rothberg, RM; Schuster, CR; Wainer, BH | 1 |
| Bläsig, J; Herz, A; Papeschi, R | 1 |
| Froede, R | 1 |
| Fog, R | 1 |
| Bläsig, J; Herz, A | 1 |
| Frings, CS | 1 |
| Hoffmeister, F; Schlichting, UU | 1 |
| Motzer, EJ; Sokolov, SL | 1 |
| Frings, CS; Queen, CA | 1 |
| Kubasik, NP; Sine, HE; Woytash, J | 1 |
| Castellano, C | 1 |
| Carmichael, FJ; Israel, Y | 1 |
| Bartlet, AL | 1 |
| Klepfisz, A; Racy, J | 1 |
| Donoso, E; Lipski, J; Stimmel, B | 1 |
| Boggan, WO | 1 |
| Carman, RS | 1 |
| Gibson, A; Pollock, D | 1 |
| Seitz, G | 1 |
| Gorodetzky, CW; Kullberg, MP | 1 |
| Ahtee, L; Boullin, DJ; Paasonen, MK; Saarnivaara, L | 1 |
| Brasted, M; Westfall, TC | 1 |
| el-Darawy, ZI; Mobarak, ZM | 1 |
| Hano, K; Kakunaga, T; Kaneto, H | 1 |
| Kakunaga, T | 1 |
| Deneau, G; Seevers, MH; Yanagita, T | 1 |
| Wikler, A | 1 |
| Deshpande, VR; Jayaswal, CL; Sharma, ML | 1 |
| Macdonald, AD | 1 |
| Del Basso, P; Longo, VG; Ziegler, H | 1 |
| Alling, S; Kaplan, E; Mayron, LW | 1 |
| Kameyama, T; Kisara, K; Nagaoka, H; Ozaki, S; Sakurada, S | 1 |
| Kumar, R; Steinberg, H; Stolerman, IP | 1 |
| Ueda, S | 1 |
| Fraser, HF; Gorodetzky, CW; Martin, WR; Rosenberg, DE | 1 |
| Bhagat, B; Shein, K | 1 |
| Beyermann, K; Kessler, A | 1 |
| Cook, A; Harrison, AJ | 1 |
| Colonna, L; Cottereau, MJ; Deniker, P; Lôo, H | 1 |
| Jamison, K; McGlothlin, W; Rosenblatt, S | 1 |
| Paton, WD | 1 |
| Hayakawa, C | 1 |
| Barbaz, BS; Bernard, PS; Chernov, HI; DeStevens, G; Partyka, DA; Wilson, DE | 1 |
| Bapna, JS; Dandiya, PC; Menon, MK | 1 |
| Nishino, K; Taga, F; Takagi, K; Takayanagi, I | 1 |
| Goldwyn, RM; Shore, S | 1 |
| Tewari, SN | 1 |
| Willis, JH | 1 |
| Nott, MW | 1 |
| Davidson, WD; Thompson, JC; Urushibara, O | 1 |
| Halbach, H | 1 |
| Michal, F | 1 |
| Fish, F; Wilson, WD | 1 |
| Blumberg, AG; Heaton, AM | 1 |
| Lajtha, A; Toth, J | 1 |
| Gunne, LM; Jonsson, J | 1 |
| Brochmann-Hanssen, E; Fontan, CR | 1 |
| Gavitt, JA; Karmin, M; Smith, AA | 1 |
| Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C | 1 |
| Botting, JH; Turmer, AD | 1 |
| Zetler, G | 1 |
| Bartholomew, AA; Reynolds, WS | 1 |
| Burks, TF; Long, JP | 1 |
| Bell, EC; Hill, HE; Wikler, A | 1 |
| Buchwald, WF; Cone, EJ; Darwin, WD; Gorodetzky, CW; Pickworth, WB; Risner, ME; Sharpe, LG | 1 |
| Lajtha, A; Reith, ME; Sershen, H | 1 |
| Spector, R | 1 |
| Ennis, C; Gaskin, M; Robbins, TW; Watson, BA | 1 |
| Baker, JP | 1 |
| Cousins, MJ; Gourlay, GK | 1 |
| Fentiman, AF; Foltz, RB; Foltz, RL | 1 |
| Copeland, ES; Yang, GC | 1 |
| Bucenieks, P; Mucha, RF; O'Shaughnessy, M; van der Kooy, D | 1 |
| Järbe, TU | 1 |
| Brake, SC; Spear, LP | 1 |
| Colp, R | 1 |
| Stewart, J | 2 |
| Akers, TK; Geiger, JD; Parmar, SS | 1 |
| Emley, GS; Hutchinson, RR | 1 |
| Kawai, T; Masukawa, Y; Suzuki, T; Yanaura, S; Yoshii, T | 1 |
| Broekkamp, CL; Fibiger, HC; Phillips, AG | 1 |
| Gilbert, LM; Golz, A; Komorowski, FS; Westerman, ST | 1 |
| Gardner, ML; Goldberg, SR | 1 |
| Spratto, GR; Wiechman, BE | 1 |
| Valdman, AV; Zvartau, EE | 1 |
| Kaneto, H; Kosaka, N | 1 |
| Cheymol, J; Vigneron, M | 1 |
| Haan, J | 1 |
| Kato, S; Yanagita, T | 1 |
| Val'dman, AV; Zvartau, EE | 1 |
| Spratto, GR; Wiechman, BE; Wood, TE | 1 |
| Cradock, JC; Poochikian, GK | 1 |
| Smith, RN | 1 |
| Cassini, M; Pigliapochi, M; Valente, D; Vansetti, G | 1 |
| Bacotti, AV | 1 |
| Göthert, M; Wehking, E | 1 |
| Ku, PY; Lee, HK; Yen, MH | 1 |
| Bilsky, EJ; French, ED; Glick, SD; Menkens, KA; Porreca, F; Reid, LD | 1 |
| Ashby, CR; Eberle, WF; Strecker, RE | 1 |
| Di Bello, MG; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S; Romano, V | 2 |
| Archer, S; Glick, SD; Maisonneuve, IM; Raucci, J | 1 |
| Albuquerque, ML; Anday, EK; Kurth, CD; Monitto, CL; Shaw, L | 1 |
| Medina, AM; Moody, DE | 1 |
| Misawa, M; Mori, T; Suzuki, T; Tsuji, M | 1 |
| Chang, SL; Kenigs, V; Moldow, RL; Zadina, JE | 1 |
| Misawa, M; Suzuki, T | 1 |
| Lasoń, W; Przewłocka, B; Przewłocki, R | 1 |
| Adams, M; Cicero, TJ; Meyer, ER; Nock, B; O'Connor, L | 1 |
| Heidbreder, C; Shippenberg, TS | 1 |
| Gardner, EL; Lepore, M; Lowinson, J; Vorel, SR | 1 |
| Bjijou, Y; Cador, M; Stinus, L | 1 |
| Chan, KM; Moriya, F; Noguchi, TT; Parnassus, WN | 1 |
| Fischman, MW; Foltin, RW; Levin, FR | 1 |
| Kintz, P; Mangin, P | 1 |
| Ator, NA; Sannerud, CA | 1 |
| Braithwaite, RA; George, S | 1 |
| Bermejo Barrera, AM; Strano Rossi, S | 1 |
| Masukawa, Y; Misawa, M; Suzuki, T | 1 |
| Pert, A; Zocchi, A | 1 |
| Käferstein, H; Schmidt, P; Sticht, G | 1 |
| Alleva, E; Fiore, M; Laviola, G; Loggi, G | 1 |
| Uchtenhagen, A | 1 |
| Corrigall, WA; Higgins, GA; Joharchi, N; Sellers, EM; Wang, Y | 1 |
| Deng, ZH; Dong, ZQ; Liu, DL | 1 |
| Moriya, F | 1 |
| Bentley, G; Bourson, A; Hargreaves, R; Iversen, S; Jackson, A; Rycroft, W; Tattersall, D; Tricklebank, M | 1 |
| Pan, CQ; Singhal, PC | 1 |
| Chiarotti, M; Offidani, C; Strano Rossi, S | 1 |
| Fey, P; Moeller, MR; Wennig, R | 1 |
| Favretto, D; Tagliaro, F; Traldi, P | 1 |
| Allgood, CC; Sniegoski, LT; Welch, MJ | 1 |
| Gastfriend, DR; Kuehnle, J; Mello, NK; Mendelson, JH; Rhoades, E; Sholar, W; Teoh, SK | 1 |
| Deroche, V; Le Moal, M; Maccari, S; Marinelli, M; Piazza, PV; Simon, H | 1 |
| Jeziorski, M; Wolf, ME | 1 |
| Balfour, HH; Chao, CC; Gekker, G; Hu, S; Peterson, PK; Schut, R | 1 |
| Aceto, MD; Bowman, ER | 1 |
| Aiello, R; Dorizzi, R; Ghielmi, S; Marigo, M; Poiesi, C; Tagliaro, F | 1 |
| Niesink, RJ; Ramsey, NF; Van Ree, JM | 1 |
| Leoni, LM; Losa, GA | 1 |
| Bacosi, A; Di Carlo, S; Pacifici, R; Zuccaro, P | 1 |
| Ostrea, EM; Romero, A; Yee, H | 1 |
| Kuehnle, J; Mello, NK; Mendelson, JH; Rhoades, EM; Sintavanarong, P; Teoh, SK | 1 |
| Driessen, B; Giertz, H; Reimann, W | 1 |
| Beitner-Johnson, D; Berhow, MT; Lindsay, RM; Nestler, EJ; Russell, DS; Self, DW; Terwilliger, RZ | 1 |
| O'Neill, WM | 1 |
| Murphey, LJ; Olsen, GD | 1 |
| Vathy, I | 1 |
| Cirimele, V; Kintz, P; Majdalani, R; Mangin, P | 1 |
| Fitzgerald, LW; Hamedani, AG; Nestler, EJ; Ortiz, J | 1 |
| Di Chiara, G; Pontieri, FE; Tanda, G | 1 |
| White, NM | 1 |
| Aoki, K; Kuroiwa, Y; Yoshida, T | 1 |
| Duvauchelle, C; Kornetsky, C | 1 |
| Ahtee, L; Kivastik, T; Piepponen, TP; Vuorikallas, K; Zharkovsky, A | 1 |
| Berhow, MT; Hiroi, N; Nestler, EJ | 1 |
| Bandarage, UK; Glick, SD; Kuehne, ME; Maisonneuve, IM; Molinari, HH | 1 |
| Bonci, A; Williams, JT | 1 |
| Ali, SF; Dillon, K; French, ED | 1 |
| Funada, M; Misawa, M; Sugano, Y; Suzuki, T | 1 |
| Bayer, BM; Ding, XZ; Hernandez, MC | 1 |
| Cox, BM; Izenwasser, S; Katz, JL; Newman, AH | 1 |
| Biała, G; Langwiński, R | 1 |
| Edel, Y; Kintz, P; Mangin, P; Tracqui, A | 1 |
| Kishimoto, Y; Misawa, M; Suzuki, T | 1 |
| Cone, EJ; Jenkins, AJ; Oyler, JM | 1 |
| Giorgi, SN; Meeker, JE | 1 |
| Hernandez, MR; Klimov, AD; Kravec, CV; Rouse, SL; Salamone, SJ; Subuhi, HS; Towt, J; Tsai, SC; Twarowska, B | 1 |
| Archer, S; Bidlack, JM; Glick, SD | 1 |
| Akil, H; Curran, EJ; Watson, SJ | 1 |
| Kuribara, H | 1 |
| Bourin, M; Hascoet, M; Lombet, A; Payeur, R; Peglion, JL | 1 |
| Caddy, B; Carvajal, R; Lora-Tamayo, C; Smith, FP; Tagliaro, F | 1 |
| Nunn, DB | 1 |
| Gerrits, MA; Kuzmin, AV; Semenova, S; Van Ree, JM; Zvartau, EE | 1 |
| Grigson, PS | 1 |
| Kishimoto, Y; Maeda, J; Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M | 1 |
| Maruta, T; Nihira, M; Tomita, Y | 1 |
| Kuhlman, G; Mosner, A; Roehm, C; Vogel, WH | 1 |
| Craft, RM; Stratmann, JA | 1 |
| Bailey, DN | 1 |
| Beydoun, A; Casey, KL; Morrow, TJ | 1 |
| Diana, M | 1 |
| Bonci, A; Fiorillo, CD; Williams, JT | 1 |
| De Vries, TJ; Hogenboom, F; Mulder, AH; Nestby, P; Schoffelmeer, AN; Vanderschuren, LJ; Wardeh, G | 1 |
| Demuth, M; Götz, ME; Koutsilieri, E; Riederer, P; Sauer, U; Sopper, S; ter Meulen, V | 1 |
| Kameyama, T; Mori, E; Ukai, M | 1 |
| Andrenyak, DM; Cheever, ML; Crouch, DJ; Kuntz, DJ; Loughmiller, DL | 1 |
| Fraser, AD | 1 |
| Marson, L; Vathy, I | 1 |
| Carboni, G; Corda, MG; Di Chiara, G; Frau, V; Giorgi, O; Valentini, V | 1 |
| Meltzer, HY; Willins, DL | 1 |
| Bhargava, HN; Cao, YJ | 1 |
| Chaperon, F; Puech, AJ; Soubrié, P; Thiébot, MH | 1 |
| Collison, IB; Guluzian, S; Sedgwick, PR; Spiehler, VR | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S; Ueda, H; Usa, M | 1 |
| Bani Sacchi, T; Di Bello, MG; Fomusi Ndisang, J; Ioannides, C; Mannaioni, PF; Masini, E; Ndisang, JF; Raspanti, S | 1 |
| LeFevour, A; Shippenberg, TS; Thompson, AC | 1 |
| Garcia, MM; Harlan, RE | 1 |
| Crivellente, F; Manetto, G; Marigo, M; Scarcella, D; Tagliaro, F | 1 |
| Glick, SD; Maisonneuve, IS | 1 |
| Costentin, J; Duterte-Boucher, D; Le Pen, G | 1 |
| Carroll, ME; Heaser, WA; Lynch, WJ | 1 |
| Dubrovsky, T; ElSohly, MA; Salamone, SJ; Towt, J; Tsai, SC; Twarowska, B | 1 |
| Boundy, VA; Chen, J; Gold, SJ; Joh, TH; Messer, CJ; Nestler, EJ; Son, JH | 1 |
| Schmidt, WJ; Tzschentke, TM | 2 |
| Holtzman, SG; Waddell, AB | 1 |
| Gatch, MB; Mello, NK; Negus, SS | 1 |
| Gewolb, IH; O'Brien, J; Slavin, RE | 1 |
| Abrous, DN; Barrot, M; Le Moal, M; Marinelli, M; Piazza, PV; Rougé-Pont, F | 2 |
| Baer, DM; Sangueza, OP | 1 |
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| Bamba, T; Bando, K; Fukusaki, E; Horie, H; Ishii, A; Katagi, M; Miyawaki, I; Sato, T; Shima, N; Suzuki, K; Tatsuno, M; Tsuchihashi, H; Zaitsu, K | 1 |
| Gao, Y; Li, Y; Lin, J; Liu, L; Peng, S; Tan, Y; Wen, Q; Zheng, C | 1 |
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| Becker, JAJ; Corde, Y; Gandía, J; Laboute, T; Le Merrer, J; Léauté, A; Pellissier, LP | 1 |
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| Babigian, CJ; Sartor, GC; Wahlestedt, C; Wiedner, HJ | 1 |
| Doustkhah, E; Khalili, NP; Liu, CH; Moradi, R; Rotkin, SV; Septiani, NLW; Yamauchi, Y | 1 |
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| An, Q; Bai, D; Huo, T; Li, X; Wang, H; Xu, B; Yang, L | 1 |
| Fan, FS | 1 |
| Calderon-Garcia, AA; Curto-Aguilera, D; Gonzalez-Nunez, V; Perez-Fernandez, M; Rodriguez-Martin, I; Sánchez-Barba, M | 1 |
| Ash, P; Darcq, E; Flores, C; Gratton, A; Hernandez, G; Kieffer, B; Moquin, L; Nouel, D; Pokinko, M | 1 |
| Copeland, C; Rock, K; Rooney, B; Sobiecka, P | 1 |
| Jones, AW | 1 |
| Becker-Krail, DD; Ketchesin, KD; Lam, TT; Logan, RW; Nairn, AC; Tseng, GC; Williams, KR; Wilson, RS; Xue, X | 1 |
| Bongiovanni, AR; Carr, GV; Desalvo, H; Do, C; Dressler, CC; Mayberry, HL; Schumacher, SP; Selamawi, D; Toussaint, AB; Wimmer, ME; Zeid, D | 1 |
| Del Bel, E; Gobira, PH; Gomes, FV; Guimarães, FS; Pedrazzi, JFC; Sales, AJ; Silveira, JR | 1 |
| Akay, M; Akay, YM; Castillo, VCG; Ganaway, A; Ohsawa, M; Ohta, J; Ohta, Y; Okada, R; Sunaga, Y; Tatsuta, K | 1 |
| Browne, SP; Covert, R; Dusick, A; Moore, CM; Tebbett, IR; Yee, GT | 1 |
| Callahan, CM; Clark, G; Grant, TM; Novack, AH; Phipps, P; Raisys, VA; Streissguth, AP | 1 |
| Amoruso, LP; Maynard, EC; Oh, W | 1 |
| Clatterbaugh, HE; Frankenfield-Chernicoff, M; Schutzman, DL; Singer, J | 1 |
| Decavalas, GO; Mastrogiannis, DS; Tejani, N; Verma, U | 1 |
| Leikin, J; Lewis, D; Moore, C | 1 |
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| Browne, S; Covert, R; Dusick, A; Moore, C; Negrusz, A; Tebbett, I | 1 |
| Dempsey, DA; Ferriero, DM; Konkol, RJ; Murphey, LJ; Olsen, GD | 1 |
| Klein, J; Koren, G; Lewis, D; Papageorgiou, A; Potter, S; Stack, DM; Stott, W; Valiante, G; Zelazo, PR | 1 |
| Behnke, M; Bertholf, RL; Casanova, OQ; Conlon, M; Eyler, FD; Lombardero, N | 1 |
| Leikin, JB; Lewis, DE; Moore, CM | 1 |
| Aldano, A; Barbieri, EJ; Chawla, H; DiGregorio, GJ; Ferko, AP; Keohane, D; Rosenstock, R; Ruch, EK | 1 |
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| Googins, MK; Lupo, VR; Thompson, LR; Yawn, BP; Yawn, RA | 1 |
| Feldman, MS; Hand, I; Kim, MH; Noble, L; Wingert, WE; Yoon, JJ | 1 |
| Knapp, DK; Lucena, JE; Ostrea, AR; Ostrea, EM; Romero, A; Utarnachitt, RB | 1 |
| Bandstra, ES; Hearn, WL; Hime, GW; Steele, BW; Wu, NC | 1 |
| Abukhalaf, IK; Abusada, GM; Alford, DD; Ansari, NA; Manno, BR; Manno, JE; Pramanik, AK; Vinzon-Bautista, I | 1 |
| Konkol, RJ; Murphey, LJ; Olsen, GD | 1 |
| Bernstein, BA; Boctor, F; Cooke, E; Fishman, S; Lewis, SC; Longobucco, DB; Rosengren, SS | 1 |
| Szeto, HH | 1 |
| Garcia, DC; Garcia, GC; Ostrea, EM; Romero, A | 1 |
| Arditti, J; Bourdon, H; Jouglard, J; Lacroze, V; Masset, D; Millet, V; Sampériz, S; Unal, D | 1 |
| Angelilli, ML; Baker, D; Covington, C; Delaney-Black, V; Hack, C; Long, J; Nordstrom-Klee, B; Ostrea, E; Romero, A; Silvestre, MA; Tagle, MT | 1 |
| Cone, EJ; Darwin, WD; Oyler, J; Preston, KL; Suess, P | 1 |
| Ostrea, EM; Reyes, MP; Salari, V; Sison, CG | 1 |
| Ostrea, AR; Ostrea, EM; Simpson, PM | 1 |
| Lewis, D; Moore, C; Negrusz, A | 1 |
| ElSohly, MA; Feng, S; Kopycki, W; Murphy, TP | 1 |
| Cabral, H; Frank, DA; McCarten, KM; Mirochnick, M; Park, H; Robson, CD; Zuckerman, B | 1 |
| Christ, MJ; Fujiwara, N; Gries, DM; Iwamoto, LM; Moore, CM; Nakamura, KT | 1 |
| Bartlett, MG; Busch, KL; Solomon, HM; Wang, P; Xia, Y | 1 |
| Dempsey, DA; Ferriero, DM; Good, W; Hajnal, BL; Jacobson, SN; Jones, RT; Partridge, JC | 1 |
| Bada, HS; Bauer, CR; ElSohly, M; Finnegan, LP; Huestis, MA; Lester, BM; Maza, PL; Shankaran, S; Smeriglio, VL; Verter, J; Walls, HH; Wright, LL | 1 |
| Arendt, R; Lewis, BA; Minnes, S; Salvator, A; Siegel, AC; Singer, LT | 1 |
| Boskovic, R; Karaskov, T; Klein, J; Koren, G; Woodland, C | 1 |
| Accornero, VH; Anthony, JC; Bandstra, ES; Johnson, AL; Morrow, CE; Xue, L | 1 |
| Augustyn, M; Beeghly, M; Bellinger, D; Cabral, H; Frank, DA; Heeren, T; Jacobs, RR | 1 |
| Anthony, JC; Bandstra, ES; Morrow, CE; Ofir, AY; Reyes, MB; Xue, L | 1 |
| Bar-Oz, B; Karaskov, T; Klein, J; Koren, G | 1 |
| Brassart, C; Codaccioni, X; Humbert, L; Lhermitte, M; Thibault, D; Vignau, J; Vinner, E | 1 |
| García-Algar, O; Marchei, E; Pacifici, R; Pellegrini, M; Pérez-Alarcón, E; Pichini, S; Puig, C; Vall, O | 1 |
| Ostrea, EM; Rintelman, W; Sison-Switala, C; Tan-Laxa, MA | 1 |
| García-Algar, O; Lozano, J; Marchei, E; Pacifici, R; Pellegrini, M; Pichini, S | 1 |
| García-Algar, O; Marchei, E; Murillo, J; Pacifici, R; Pellegrini, M; Pichini, S; Puig, C; Vall, O; Zuccaro, P | 1 |
| Bada, HS; Bauer, CR; Finnegan, LP; Krause-Steinrauf, H; Langer, JC; Lester, B; Maza, PL; Shankaran, S; Smeriglio, VL; Verter, J; Wright, LL | 1 |
| Alder, SC; Christensen, RD; Jones, J; Jones, M; Montgomery, D; Plate, C | 1 |
| Garcia-Bournissen, F; Karaskov, T; Koren, G; Rokach, B | 1 |
| Kirchner, HL; Lewis, BA; Minnes, S; Satayathum, S; Short, EJ; Singer, LT; Weishampel, P | 1 |
| Choo, RE; Huestis, MA; Johnson, RE; Jones, HE; Kacinko, SL | 1 |
| Gray, TR; Huestis, MA; Shakleya, DM | 1 |
| Keith, L; Marin, SJ; McMillin, GA; Merrell, M | 1 |
| Alvarez, I; Bermejo, AM; Cabarcos, P; Fernández, P; López, P; Tabernero, MJ | 1 |
| Karaskov, T; Koren, G; Moller, M | 1 |
| Choo, RE; Concheiro, M; Elko, A; Gray, TR; Huestis, MA; Jansson, LM; Jones, HE; Williams, E | 1 |
| Marin, SJ; McMillin, GA; Merrell, M | 1 |
| de Castro, A; Gray, TR; Huestis, MA; Johnson, RE; Jones, HE; Shakleya, DM | 2 |
| García-Algar, O; García-Serra, J; Joya, X; Pichini, S; Ramis, J; Simó, S; Vall, O | 1 |
| Concheiro, M; Concheiro-Guisán, A; Cruz-Landeira, A; de Castro, A; González-Colmenero, E; Lendoiro, E; López-Rivadulla, M | 1 |
| Delano, K; Gareri, J; Koren, G | 1 |
| Diniz, EM; Lima, MB; Mantovani, Cde C; Menck, Rde A; Oliveira, CD; Yonamine, M | 1 |
| Krasowski, MD; McMillin, GA; Rysgaard, CD; Sinclair, LL; Strathmann, FG; Wood, KE | 1 |
| Krasowski, MD; McMillin, GA; Strathmann, FG; Wood, KE | 1 |
| Calvaresi, V; García-Algar, O; Joya, X; Marchei, E; Pacifici, R; Pichini, S; Salat-Batlle, J | 1 |
| D'Avila, FB; Ferreira, PC; Fröehlich, PE; Limberger, RP; Pechansky, F; Pereira, AG; Salazar, FR; Santos, MK | 1 |
| D'Avila, FB; Fröehlich, PE; Limberger, RP | 1 |
| Concheiro, M; Concheiro-Guisan, A; Cruz-Landeira, A; de Castro, A; Gónzalez-Colmenero, E; Lendoiro, E; López-Rivadulla, M; Macias-Cortiña, M; Peñas-Silva, P | 1 |
| Marin, SJ; McMillin, GA; Wu, F | 1 |
| Chertok, I; Cottrell, L; Giacobbi, P; Long, L; Stabler, M; Yossuck, P | 1 |
| McMillin, GA; Scroggin, TL | 1 |
| Goggin, MM; Janis, GC | 1 |
| Busardò, FP; Carlier, J; Di Trana, A; Huestis, MA; La Maida, N; Pichini, S | 1 |
| Danell, AS; Forbes, L; Kew, K; Kuehn, D; Mamillapalli, SS; May, L; McIntyre, K; Poppenfuse, S; Ravisankar, S; Rushing, B; Smith-Joyner, A; Strom, C | 1 |
| McMillin, GA; Pandya, V; Wilker, C | 1 |
57 review(s) available for cocaine and morphine
| Article | Year |
|---|---|
Radioimmunoassays of drugs of abuse in humans: a review.
Topics: Amphetamines; Barbiturates; Body Fluids; Cocaine; Humans; Illicit Drugs; Lysergic Acid Diethylamide; Methadone; Methaqualone; Morphine; Nicotine; Pharmaceutical Preparations; Radioimmunoassay | 1977 |
Brain 5-hydroxytryptamine metabolism: adaptive changes after long-term administration of psychotropic drugs.
Topics: Adrenal Cortex Hormones; Animals; Brain; Cocaine; Diazepam; Hyperthyroidism; Hypothyroidism; Lithium; Morphine; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1978 |
An experimental analysis of behavioral factors in drug dependence.
Topics: Administration, Oral; Alcoholism; Amphetamine; Animals; Behavior, Animal; Cannabis; Chlorpromazine; Cocaine; Dextroamphetamine; Drinking Behavior; Dronabinol; Ethanol; Humans; Imipramine; Injections, Intravenous; Macaca mulatta; Morphine; Pentobarbital; Reinforcement Schedule; Secobarbital; Social Environment; Substance-Related Disorders; Time Factors | 1975 |
Brain mechanisms of drug-induced reinforcement.
Topics: Animals; Brain; Cocaine; Morphine; Motivation; Psychotropic Drugs; Rats; Receptors, Dopamine; Receptors, Opioid; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Common intracellular actions of chronic morphine and cocaine in dopaminergic brain reward regions.
Topics: Animals; Brain; Cocaine; Cyclic AMP; GTP-Binding Proteins; Limbic System; Locus Coeruleus; Morphine; Rats; Rats, Inbred Strains; Reward; Tyrosine 3-Monooxygenase | 1992 |
LP-BM5, a murine model of acquired immunodeficiency syndrome: role of cocaine, morphine, alcohol and carotenoids in nutritional immunomodulation.
Topics: Animals; Carotenoids; Cocaine; Ethanol; Immunity, Innate; Mice; Mice, Inbred C57BL; Morphine; Murine Acquired Immunodeficiency Syndrome; Protein Deficiency | 1992 |
Basal forebrain involvement in self-administration of drugs of abuse.
Topics: Amphetamine; Animals; Cocaine; Heroin; Morphine; Neurotoxins; Prosencephalon; Self Administration; Substance-Related Disorders | 1991 |
Effects of cocaine and other drugs of abuse on immune function.
Topics: Antigens, CD; CD4-CD8 Ratio; Cocaine; Drug Interactions; Ethanol; Gene Expression Regulation; Heroin; Heroin Dependence; Humans; Immune System; Morphine; Rosette Formation; Substance-Related Disorders; T-Lymphocyte Subsets | 1991 |
Placental toxicology: tobacco smoke, abused drugs, multiple chemical interactions, and placental function.
Topics: Amino Acids; Cocaine; DNA Damage; Drug Interactions; Female; Humans; Morphine; Placenta; Pregnancy; Smoking; Substance-Related Disorders | 1991 |
Effects of morphine, cocaine, and heroin on nutrition.
Topics: Animals; Cocaine; Heroin; Humans; Morphine; Narcotics; Nutrition Disorders; Nutritional Physiological Phenomena; Substance-Related Disorders | 1990 |
Forensic science.
Topics: Amphetamines; Barbiturates; Biochemical Phenomena; Biochemistry; Cannabinoids; Cocaine; Dermatoglyphics; Ethanol; Forensic Medicine; Glass; Hair; Humans; Morphine; Narcotics; Petroleum; Pharmaceutical Preparations; Plants; Poisons; Solvents | 1985 |
On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Caffeine; Catalepsy; Cocaine; Compulsive Behavior; Corpus Striatum; Disease Models, Animal; Dopamine; Hippocampus; Humans; Lysergic Acid Diethylamide; Methamphetamine; Methylphenidate; Morphine; Norepinephrine; Pemoline; Phenmetrazine; Psychoses, Substance-Induced; Rats; Reserpine; Thalamus; Tranquilizing Agents | 1972 |
[Neurobiologic aspects of the morphine addictions].
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dopamine; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Tolerance; Guinea Pigs; Humans; Mice; Models, Biological; Morphine; Morphine Dependence; Rats; Receptors, Drug; Serotonin; Substance Withdrawal Syndrome | 1974 |
Drug screening.
Topics: Amphetamine; Barbiturates; Bromides; Cocaine; Codeine; Drug Stability; Ethchlorvynol; Fluorometry; Glutethimide; Hemagglutination Inhibition Tests; Humans; Meprobamate; Methadone; Methods; Morphine; Pharmaceutical Preparations; Phenothiazines; Quinine; Salicylates | 1973 |
GC/MS assays for abused drugs in body fluids.
Topics: Amphetamines; Chromatography, Gas; Cocaine; Diazepam; Dronabinol; Humans; Mass Spectrometry; Mescaline; Methadone; Methaqualone; Morphine; Pharmaceutical Preparations; Phencyclidine; Substance-Related Disorders | 1980 |
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Cocaine; Exploratory Behavior; Female; Haloperidol; Learning; Limbic System; Male; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Social Behavior | 1983 |
Second-order schedules: extended sequences of behavior controlled by brief environmental stimuli associated with drug self-administration.
Topics: Animals; Behavior, Animal; Cocaine; Drug Administration Schedule; Environment; Humans; Injections, Intramuscular; Injections, Intravenous; Macaca mulatta; Morphine; Nicotine; Rats; Saimiri; Self Administration; Substance-Related Disorders | 1981 |
[Drugs and opiates: an overview from anthropological, psychological, socio-cultural, biochemical and medical perspectives].
Topics: Adult; Alcoholism; Amphetamines; Chemical Phenomena; Chemistry; Cocaine; Emergencies; Female; Hallucinogens; Humans; Male; Morphine; Narcotics; Psychotropic Drugs; Socioeconomic Factors | 1981 |
Cardiovascular effects of cocaine in humans: laboratory studies.
Topics: Alcohol Drinking; Arousal; Blood Pressure; Calcium Channel Blockers; Cannabinoids; Cardiovascular System; Cocaine; Desipramine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; Heart Rate; Hemodynamics; Humans; Morphine; Motor Activity; Receptors, Adrenergic | 1995 |
Enhancement of HIV-1 replication by opiates and cocaine: the cytokine connection.
Topics: Cocaine; Cytokines; Cytomegalovirus; HIV-1; Humans; Leukocytes, Mononuclear; Morphine; Narcotics; Virus Replication | 1993 |
Effects of morphine and cocaine on breathing control in neonatal animals: a minireview.
Topics: Animals; Animals, Newborn; Cocaine; Female; Humans; Morphine; Narcotics; Pregnancy; Respiratory Mechanics | 1995 |
Effects of prenatal morphine and cocaine on postnatal behaviors and brain neurotransmitters.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Female; Humans; Male; Morphine; Narcotics; Neurotransmitter Agents; Pregnancy; Prenatal Exposure Delayed Effects | 1995 |
Addictive drugs as reinforcers: multiple partial actions on memory systems.
Topics: Amphetamines; Animals; Behavior, Animal; Brain; Cocaine; Ethanol; Hippocampus; Learning; Memory; Morphine; Nicotine; Reinforcement, Psychology; Self Administration | 1996 |
Dopamine, a common substrate for the rewarding effects of brain stimulation reward, cocaine, and morphine.
Topics: Animals; Brain; Cocaine; Dopamine Uptake Inhibitors; Humans; Morphine; Narcotics; Psychomotor Performance; Reward; Stimulation, Chemical | 1994 |
Cyclazocine revisited.
Topics: Animals; Cocaine; Cyclazocine; Drug Tolerance; Humans; Morphine; Morphine Dependence; Narcotic Antagonists; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Substance-Related Disorders | 1996 |
Drugs of abuse and dopamine cell activity.
Topics: Amphetamine; Animals; Brain; Cocaine; Dopamine; Humans; Morphine; Neurons; Substance-Related Disorders | 1998 |
Drugs of abuse and immediate-early genes in the forebrain.
Topics: Amphetamines; Animals; Caffeine; Cocaine; Dronabinol; Gene Expression Regulation; Genes, Immediate-Early; Humans; Illicit Drugs; Immediate-Early Proteins; Morphine; Nicotine; Prosencephalon; Substance-Related Disorders | 1998 |
Mechanisms of antiaddictive actions of ibogaine.
Topics: Animals; Cocaine; Female; Ibogaine; Morphine; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Tobacco Use Disorder | 1998 |
Identifying genes for alcohol and drug sensitivity: recent progress and future directions.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Chromosome Mapping; Cocaine; Crosses, Genetic; Ethanol; Female; Forecasting; Genetic Predisposition to Disease; Humans; Lod Score; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Morphine; Pentobarbital; Quantitative Trait, Heritable; Substance Withdrawal Syndrome; Substance-Related Disorders | 1999 |
Recreational drug misuse: issues for the cardiologist.
Topics: Adolescent; Adult; Amphetamines; Cannabis; Cardiovascular Diseases; Child; Cocaine; Drug Overdose; Female; Hallucinogens; Heroin; Humans; Lysergic Acid Diethylamide; Male; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Psilocybin; Substance-Related Disorders | 2000 |
[Pharmacokinetic and toxicokinetic parameters of some drugs of abuse].
Topics: Amphetamines; Cannabinoids; Cannabis; Cocaine; Codeine; Humans; Illicit Drugs; Lysergic Acid Diethylamide; Morphine | 2001 |
Mechanisms of action of ibogaine: relevance to putative therapeutic effects and development of a safer iboga alkaloid congener.
Topics: Animals; Behavior, Animal; Cocaine; Humans; Ibogaine; Morphine; Motor Activity; Self Administration | 2001 |
Second-order schedules of drug self-administration in animals.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Interactions; Extinction, Psychological; Food; Morphine; Photic Stimulation; Piperazines; Reinforcement Schedule; Self Administration; Time Factors | 2002 |
The dopamine-containing neuron: maestro or simple musician in the orchestra of addiction?
Topics: Amphetamine; Animals; Cocaine; Dopamine; Humans; Mesencephalon; Models, Biological; Morphine; Narcotics; Nerve Endings; Neurons; Nicotine; Receptors, Dopamine; Substance-Related Disorders | 2003 |
Drug-induced neurobehavioral plasticity: the role of environmental context.
Topics: Amphetamine; Animals; Behavior; Brain; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Environment; Exploratory Behavior; Gene Expression Regulation; Humans; Morphine; Narcotics; Neuronal Plasticity; Substance-Related Disorders | 2004 |
[Behavioral and pharmacological characteristics of mice lacking the dopamine transporter].
Topics: Adaptation, Physiological; Amphetamines; Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Humans; Hyperkinesis; Mice; Mice, Knockout; Morphine; Narcotics | 2004 |
Toxicokinetics of drugs of abuse: current knowledge of the isoenzymes involved in the human metabolism of tetrahydrocannabinol, cocaine, heroin, morphine, and codeine.
Topics: Cocaine; Codeine; Dronabinol; Heroin; Humans; Illicit Drugs; Isoenzymes; Morphine; Narcotics; Psychotropic Drugs; Substance-Related Disorders | 2006 |
Nicotine, alcohol and cocaine coupling to reward processes via endogenous morphine signaling: the dopamine-morphine hypothesis.
Topics: Alcohols; Animals; Cocaine; Humans; Models, Biological; Morphine; Nicotine; Reward; Signal Transduction | 2007 |
The influence of putrefaction and sample storage on post-mortem toxicology results.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amphetamines; Bacteria; Cocaine; Forensic Toxicology; Humans; Morphine; Oxidative Phosphorylation; Postmortem Changes; Time Factors | 2010 |
The nociceptin/orphanin FQ receptor (NOP) as a target for drug abuse medications.
Topics: Alcoholism; Analgesics, Opioid; Animals; Behavior, Addictive; Buprenorphine; Cocaine; Dopamine; Drug Combinations; Humans; Imidazoles; Ligands; Mice; Mice, Knockout; Morphine; Nociceptin; Nociceptin Receptor; Opioid Peptides; Psychotropic Drugs; Rats; Receptors, Opioid; Spiro Compounds; Substance-Related Disorders | 2011 |
Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse.
Topics: Aggression; Amines; Amphetamine; Anhedonia; Animals; Brain; Brain Stem; Cocaine; Female; Gene Expression Regulation; Genome; Male; Mice; Morphine; Peptides; Rats; Stress, Psychological; Substance-Related Disorders; Time Factors; Violence | 2011 |
Genes and pathways co-associated with the exposure to multiple drugs of abuse, including alcohol, amphetamine/methamphetamine, cocaine, marijuana, morphine, and/or nicotine: a review of proteomics analyses.
Topics: Amphetamines; Animals; Brain; Brain Chemistry; Cannabinoids; Cannabis; Cocaine; Ethanol; Gene Expression; Gene Expression Profiling; Humans; Illicit Drugs; Methamphetamine; Morphine; Nicotine; Proteomics; Substance-Related Disorders | 2011 |
[Structural plasticity associated with drugs addiction].
Topics: Amphetamine; Animals; Brain; Cocaine; Humans; Morphine; Neuronal Plasticity; Nicotine; Reward; Substance-Related Disorders; Synapses | 2011 |
[The effect of psychoactive substances on expression of heat shock protein 70].
Topics: Animals; Apoptosis; Cocaine; Ethanol; Fever; HSP70 Heat-Shock Proteins; Humans; Morphine; Psychotropic Drugs | 2012 |
HIV-1 gp120 and drugs of abuse: interactions in the central nervous system.
Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Animals; Apoptosis; Blood-Brain Barrier; Central Nervous System; Central Nervous System Stimulants; Cocaine; HIV Envelope Protein gp120; HIV-1; Humans; Methamphetamine; Mice; Morphine; Oxidative Stress; Rats; Substance-Related Disorders | 2012 |
Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Dynorphins; Gene Expression Regulation; Humans; Mammals; Morphine; Motivation; Narcotics; Nucleus Accumbens; Receptors, Neurotransmitter; Reward; Signal Transduction; Substance-Related Disorders; Transcriptional Activation | 2013 |
Mitoepigenetics and drug addiction.
Topics: 5-Methylcytosine; Amphetamines; Animals; Cocaine; Cytosine; DNA, Mitochondrial; Dose-Response Relationship, Drug; Epigenesis, Genetic; Ethanol; Gene Expression; Humans; Mitochondria; Morphine; Oxidative Stress; Substance-Related Disorders | 2014 |
[Role of alteration in intracellular Ca2+ dynamics in the development of drug dependence].
Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Signaling; Cocaine; Humans; Methamphetamine; Mice; Morphine; Neurons; Rats; Ryanodine Receptor Calcium Release Channel; Substance-Related Disorders; Up-Regulation | 2014 |
Reflections on: "A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function".
Topics: Animals; Cocaine; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; GTP-Binding Proteins; Humans; Locus Coeruleus; Morphine; Nucleus Accumbens; Rats; Reward; Substance-Related Disorders; Up-Regulation | 2016 |
Underexplored Opportunities for Natural Products in Drug Discovery.
Topics: Biological Products; Cocaine; Drug Discovery; Estradiol; Humans; Molecular Conformation; Morphine; Quinine | 2016 |
Neuronal mechanisms mediating pathological reward-related behaviors: A focus on silent synapses in the nucleus accumbens.
Topics: Animals; Cocaine; Drug-Seeking Behavior; Morphine; Neurons; Nucleus Accumbens; Reward; Synapses | 2018 |
Nanoarchitectonics for Abused-Drug Biosensors.
Topics: Biosensing Techniques; Cocaine; Illicit Drugs; Morphine | 2022 |
Cocaine metabolites in the neonate: potential for toxicity.
Topics: Butyrylcholinesterase; Central Nervous System Diseases; Cocaine; Female; Fetal Blood; Fever; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Neonatal Abstinence Syndrome; Pregnancy; Prospective Studies; Respiratory Distress Syndrome, Newborn | 1994 |
Kinetics of drug transfer to the fetus.
Topics: Amniotic Fluid; Animals; Cannabis; Cocaine; Female; Fetus; Hair; Humans; Maternal-Fetal Exchange; Meconium; Narcotics; Pregnancy | 1993 |
Determination of drugs of abuse in meconium.
Topics: Amphetamines; Cannabis; Chromatography, High Pressure Liquid; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoenzyme Techniques; Infant, Newborn; Meconium; Narcotics; Phencyclidine; Radioimmunoassay; Substance Abuse Detection | 1998 |
Cocaine and crack cocaine abuse by pregnant or lactating mothers and analysis of its biomarkers in meconium and breast milk by LC-MS-A review.
Topics: Biomarkers; Chromatography, Liquid; Cocaine-Related Disorders; Crack Cocaine; Female; Forensic Toxicology; Humans; Lactation; Mass Spectrometry; Meconium; Milk, Human; Pregnancy | 2016 |
Testing Unconventional Matrices to Monitor for Prenatal Exposure to Heroin, Cocaine, Amphetamines, Synthetic Cathinones, and Synthetic Opioids.
Topics: Alkaloids; Amphetamines; Analgesics, Opioid; Cocaine; Drug Monitoring; Female; Hair; Heroin; Humans; Meconium; Placenta; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Substance-Related Disorders; Umbilical Cord | 2020 |
16 trial(s) available for cocaine and morphine
| Article | Year |
|---|---|
The Brompton cocktail.
Topics: Chemistry, Pharmaceutical; Chlorpromazine; Clinical Trials as Topic; Cocaine; Drug Combinations; Drug Evaluation; Female; Heroin; Humans; London; Male; Morphine; Neoplasms; Pain, Intractable; Palliative Care | 1979 |
The Brompton mixture versus morphine solution given orally: effects on pain.
Topics: Administration, Oral; Analgesics; Chloroform; Clinical Trials as Topic; Cocaine; Codeine; Confusion; Double-Blind Method; Drug Combinations; Drug Evaluation; Ethanol; Humans; Morphine; Nausea; Neoplasms; Pain, Intractable; Phenothiazines; Sleep Stages | 1979 |
Cocaine and morphine interaction in acute and chronic cancer pain.
Topics: Adult; Aged; Clinical Trials as Topic; Cocaine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain, Postoperative; Random Allocation | 1987 |
Studies of the dependence-producing potential of the narcotic antagonist 2-cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan (cyclazocine, WIN-20,740, ARC II-c-3).
Topics: Amphetamine; Analgesics; Barbiturates; Cannabis; Clinical Trials as Topic; Cocaine; Cyclazocine; Drug Tolerance; Euphoria; Humans; Morphine; Nalorphine; Narcotic Antagonists; Pupil; Substance Withdrawal Syndrome; Substance-Related Disorders | 1965 |
Buprenorphine effects on morphine- and cocaine-induced subjective responses by drug-dependent men.
Topics: Administration, Sublingual; Adult; Ambulatory Care; Arousal; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Male; Morphine; Morphine Dependence; Prognosis; Substance Abuse, Intravenous; Substance-Related Disorders; Treatment Outcome | 1994 |
Acute interactions of buprenorphine with intravenous cocaine and morphine: an investigational new drug phase I safety evaluation.
Topics: Administration, Sublingual; Adult; Arousal; Blood Pressure; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Heroin Dependence; Humans; Liver Function Tests; Male; Morphine; Single-Blind Method; Substance-Related Disorders | 1993 |
The cognitive and psychomotor effects of opioid drugs in cancer pain management.
Topics: Adult; Amphetamines; Analgesics, Opioid; Buprenorphine; Central Nervous System Stimulants; Chronic Disease; Cocaine; Codeine; Cognition; Dextropropoxyphene; Dopamine Uptake Inhibitors; Humans; Methylphenidate; Morphine; Neoplasms; Pain; Psychomotor Performance; Randomized Controlled Trials as Topic; Reaction Time; Thiazoles | 1994 |
Morphine- and cocaine-induced conditioned place preference: effects of quinpirole and preclamol.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Agonists; Male; Morphine; Narcotics; Piperidines; Rats; Rats, Wistar; Synaptic Transmission | 1996 |
Sweat testing in opioid users with a sweat patch.
Topics: Amphetamines; Benzodiazepines; Buprenorphine; Cannabinoids; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Heroin; Heroin Dependence; Humans; Illicit Drugs; Morphine; Morphine Derivatives; Reproducibility of Results; Sweat | 1996 |
Influence of morphine sulfate on cocaine-induced coronary vasoconstriction.
Topics: Administration, Intranasal; Blood Pressure; Cocaine; Coronary Artery Disease; Coronary Vessels; Drug Administration Schedule; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Narcotics; Substance-Related Disorders; Vasoconstriction | 2002 |
Needle exchange and injection drug use frequency: a randomized clinical trial.
Topics: Adult; Alaska; Algorithms; Amphetamine; Cocaine; Cohort Studies; Community Pharmacy Services; Female; Humans; Injections; Male; Morphine; Needle-Exchange Programs; Needles; Patient Education as Topic; Program Evaluation; Substance Abuse, Intravenous; Surveys and Questionnaires; Syringes | 2003 |
An LC-MS-MS method for the comprehensive analysis of cocaine and cocaine metabolites in meconium.
Topics: Chromatography, Liquid; Cocaine; Female; Humans; Illicit Drugs; Infant, Newborn; Mass Spectrometry; Meconium; Pregnancy | 2000 |
Acute neonatal effects of cocaine exposure during pregnancy.
Topics: Abnormalities, Drug-Induced; Acute Disease; Adolescent; Adult; Birth Weight; Cocaine; Cocaine-Related Disorders; Female; Fetus; Gestational Age; Humans; Infant, Newborn; Meconium; Middle Aged; Neonatal Screening; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; United States | 2005 |
Correlations of maternal buprenorphine dose, buprenorphine, and metabolite concentrations in meconium with neonatal outcomes.
Topics: Adult; Buprenorphine; Cocaine; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Maternal Behavior; Maternal-Fetal Exchange; Meconium; Methadone; Narcotic Antagonists; Neonatal Abstinence Syndrome; Nicotine; Opiate Alkaloids; Opioid-Related Disorders; Pregnancy; Smoking | 2008 |
Maternal methadone dose, placental methadone concentrations, and neonatal outcomes.
Topics: Analgesics, Opioid; Apgar Score; Birth Weight; Body Size; Cephalometry; Cocaine; Female; Gestational Age; Humans; Infant, Newborn; Maternal Exposure; Meconium; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Pyrrolidines; Tissue Distribution | 2011 |
Methadone, cocaine, opiates, and metabolite disposition in umbilical cord and correlations to maternal methadone dose and neonatal outcomes.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pyrrolidines; Umbilical Cord | 2011 |
813 other study(ies) available for cocaine and morphine
| Article | Year |
|---|---|
N-(2,4,5-Trihydroxyphenehtyl)normetazocine, a potential irreversible inhibitor of the narcotic receptor.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Benzomorphans; Brain; Cyclazocine; Depression, Chemical; In Vitro Techniques; Male; Mice; Morphinans; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Protein Binding; Rats; Receptors, Opioid | 1977 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Treatment of terminal conditions with hyperalgia].
Topics: Analgesics, Opioid; Chloroform; Cocaine; Drug Combinations; Ethanol; Humans; Morphine; Pain, Intractable; Terminal Care | 1978 |
Discriminative stimulus properties of psychomotor stimulants in the cat.
Topics: Animals; Cats; Central Nervous System Stimulants; Clozapine; Cocaine; Dextroamphetamine; Discrimination, Psychological; Feeding Behavior; Female; Male; Morphine; Reinforcement Schedule | 1979 |
Use of the Brompton mixture in treating the chronic pain of malignant disease.
Topics: Aged; Antipsychotic Agents; Cocaine; Drug Combinations; Ethanol; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Palliative Care; Phenothiazines; Solutions | 1976 |
The Brompton mixture: effects on pain in cancer patients.
Topics: Affect; Antipsychotic Agents; Attitude; Cocaine; Drug Combinations; Ethanol; Evaluation Studies as Topic; Female; Hospital Units; Humans; Male; Morphine; Neoplasms; Pain, Intractable; Palliative Care; Phenothiazines; Sensation; Solutions; Surveys and Questionnaires | 1976 |
Brompton's cocktail: making good-byes possible.
Topics: Cocaine; Female; Humans; Leiomyosarcoma; Morphine; Palliative Care; Terminal Care | 1978 |
The Brompton cocktail.
Topics: Administration, Oral; Cocaine; Drug Combinations; Ethanol; Heroin; Humans; London; Morphine; Neoplasms; Palliative Care; Terminal Care | 1979 |
Changes in locomotor activity and naloxone-induced jumping in mice produced by WIN 35, 197-2 (ethylketazocine) and morphine.
Topics: Animals; Cocaine; Cyclazocine; Female; Humans; Mice; Morphine; Motor Activity; Naloxone; Narcotics; Substance Withdrawal Syndrome; Time Factors | 1978 |
Effects of passive immunization against morphine on heroin self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Haplorhini; Heroin; Heroin Dependence; Humans; Immune Sera; Immunity, Maternally-Acquired; Macaca mulatta; Morphine; Naloxone; Self Administration | 1978 |
A new device for the simultaneous measurement of locomotor and stereotypic frequency in mice.
Topics: Animals; Behavior; Body Weight; Cocaine; Dextroamphetamine; Humans; Male; Methylphenidate; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Psychology, Experimental; Stereotyped Behavior | 1979 |
Enhancement of drug-seeking behavior by environmental stimuli associated with cocaine or morphine injections.
Topics: Animals; Appetitive Behavior; Cocaine; Conditioning, Operant; Environment; Haplorhini; Morphine; Reinforcement Schedule; Saimiri | 1979 |
[Effects of diazepam on six drug-induced locomotor hyperactivities in mice (author's transl)].
Topics: Animals; Cocaine; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Male; Methamphetamine; Mice; Morphine; Motor Activity; Reserpine; Trihexyphenidyl | 1975 |
Increased running response to morphine in morphine-pretreated mice.
Topics: Aging; Analgesics, Opioid; Animals; Animals, Newborn; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hot Temperature; Levorphanol; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Morphine; Motor Activity; Naloxone; Reaction Time; Species Specificity; Stereoisomerism; Stimulation, Chemical; Time Factors | 1975 |
Selective induction of hepatic drug metabolizing enzymes by lithium treatment in dogs.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Anisoles; Cocaine; Dogs; Enzyme Induction; Female; Lithium; Liver; Methyltransferases; Mixed Function Oxygenases; Morphine | 1975 |
Brompton's solution: regime for chronic pain relief.
Topics: Cocaine; Humans; Morphine; Pain, Intractable; Prochlorperazine | 1978 |
The Brompton Cocktail.
Topics: Acute Disease; Adult; Chronic Disease; Cocaine; Ethanol; Female; Humans; Male; Morphine; Neoplasms; Pain, Intractable | 1978 |
Sensitization to cocaine stimulation in mice.
Topics: Animals; Brain Chemistry; Cocaine; Cycloheximide; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Imipramine; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Motor Activity; Norepinephrine; Reserpine; Species Specificity; Stimulation, Chemical; Time Factors | 1977 |
Discrete-trial control of cocaine self-injection behaviour in squirrel monkeys: effects of morphine, naloxone, and chlorpromazine.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Haplorhini; Male; Morphine; Naloxone; Reinforcement Schedule; Saimiri; Self Administration; Time Factors | 1977 |
Second-order schedules of intravenous drug self-administration in rhesus monkeys.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Haplorhini; Humans; Macaca mulatta; Morphine; Naloxone; Reinforcement Schedule; Self Administration; Substance-Related Disorders | 1977 |
Intracranial self-stimulation thresholds: a model for the hedonic effects of drugs of abuse.
Topics: Animals; Brain; Cocaine; Cyclazocine; Dose-Response Relationship, Drug; Illicit Drugs; Male; Models, Neurological; Morphine; Nalorphine; Naloxone; Pentazocine; Pharmacology; Phencyclidine; Rats; Self Stimulation; Sensory Thresholds | 1979 |
Gas-liquid chromatographic determination of morphine, heroin, and cocaine.
Topics: Chromatography, Gas; Cocaine; Heroin; Methods; Morphine | 1979 |
[Experiences with an oral cocaine-morphine solution (Brompton mixture) in the treatment of severe pain in patients with neoplasms].
Topics: Administration, Oral; Analgesia; Cocaine; Drug Combinations; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain | 1979 |
Euphorigenic drugs: effects on the reward pathways of the brain.
Topics: Amphetamine; Animals; Brain; Cocaine; Electroencephalography; Euphoria; Morphine; Narcotic Antagonists; Narcotics; Neural Pathways; Pentazocine; Phencyclidine; Rats; Reward; Self Stimulation | 1979 |
Incidence of cocaine metabolites in urine specimens from medical examiners' cases.
Topics: Cadaver; Cocaine; Humans; Morphine; Radioimmunoassay | 1979 |
Value of cocaine in opiate-containing elixirs.
Topics: Cocaine; Drug Combinations; Humans; Morphine; Terminal Care | 1977 |
Drug discrimination and generalization in pigeons.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Methocarbamol; Morphine; Pentobarbital; Pharmaceutical Preparations | 1977 |
Cocaine-related death.
Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Brain Edema; Cocaine; Ethanol; Female; Forensic Medicine; Humans; Intracranial Aneurysm; Lidocaine; Male; Morphine; Nortriptyline; Phenmetrazine; Substance-Related Disorders; Suicide; Tissue Distribution | 1977 |
Naltrexone, morphine and cocaine interactions in mice and rats.
Topics: Animals; Cocaine; Drug Interactions; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Reaction Time; Reflex | 1978 |
[Therapy of complications due to neoplasm metastases].
Topics: Cocaine; Female; Humans; Laminectomy; Male; Morphine; Neoplasm Metastasis; Pain; Paralysis; Spinal Neoplasms; Tranquilizing Agents | 1978 |
Determination of drugs of abuse in body fluids by radioimmunoassay.
Topics: Amphetamines; Barbiturates; Body Fluids; Cocaine; Humans; Lysergic Acid Diethylamide; Methadone; Methaqualone; Morphine; Radioimmunoassay; Substance-Related Disorders | 1978 |
[Simple and easy method for measurement of ambulatory activity in mice (author's transl)].
Topics: Amphetamines; Animals; Cocaine; Dose-Response Relationship, Drug; Male; Methamphetamine; Methods; Mice; Morphine; Motor Activity; Time Factors | 1978 |
[Rapid method for the identification and quantitative determination of cocaine, heroin and morphine in illicit drugs].
Topics: Chromatography, Thin Layer; Cocaine; Heroin; Illicit Drugs; Methods; Morphine; Pharmaceutical Preparations; Spectrophotometry, Ultraviolet | 1978 |
Characteristics of behavior controlled by scheduled injections of drugs.
Topics: Animals; Barbiturates; Behavior, Animal; Cocaine; Drug Administration Schedule; Environment; Food; Haplorhini; Humans; Macaca mulatta; Methadone; Methohexital; Morphine; Pharmaceutical Preparations; Reinforcement Schedule; Saimiri; Substance-Related Disorders; Time Factors | 1975 |
Behavior maintained under a second-order schedule by intramuscular injection of morphine or cocaine in rhesus monkeys.
Topics: Animals; Behavior, Animal; Cocaine; Haplorhini; Injections, Intravenous; Macaca mulatta; Male; Morphine; Nalorphine; Reinforcement Schedule; Time Factors | 1976 |
The different effect of humoral modulators on the morphine- and central nervous system stimulant-induced hyperactivity of rats.
Topics: Acetylcholine; Animals; Atropine; Atropine Derivatives; Caffeine; Catecholamines; Cocaine; Male; Methamphetamine; Methyltyrosines; Morphine; Motor Activity; Rats; Scopolamine; Scopolamine Derivatives | 1977 |
Drug abuse proficiency testing.
Topics: Barbiturates; Cocaine; Dextroamphetamine; False Negative Reactions; Humans; Illicit Drugs; Laboratories; Methadone; Methamphetamine; Morphine; Pharmaceutical Preparations; Substance-Related Disorders; United States | 1977 |
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol | 1977 |
Toxic interactions of stimulants, narcotics and narcotic antagonists.
Topics: Animals; Cocaine; Cyclazocine; Dextroamphetamine; Drug Synergism; Male; Methadone; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats | 1977 |
AMT catalepsy and hypokinesia: interaction with morphine and cocaine.
Topics: Animals; Body Temperature; Brain Chemistry; Catalepsy; Catecholamines; Cocaine; Drug Interactions; Drug Tolerance; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Psychomotor Disorders; Rats | 1976 |
A neurobiological model for the symmetrical prophylactic action of lithium in bipolar affective disorder.
Topics: Animals; Bipolar Disorder; Brain; Cocaine; Corpus Striatum; Humans; Kinetics; Lithium; Male; Mesencephalon; Models, Biological; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1976 |
Fallibility of urine drug screens in monitoring methadone programs.
Topics: Amphetamine; Cocaine; Heroin Dependence; Humans; Laboratories; Licensure; Methadone; Morphine; Pharmaceutical Preparations; Secobarbital; Substance-Related Disorders; United States | 1976 |
[Effect of D-, M- and T-antagonists of serotonin on its absorption by human thrombocytes].
Topics: Absorption; Blood Platelets; Cocaine; Depression, Chemical; Dihydroergotamine; Humans; Indoles; Methysergide; Morphine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1976 |
Cocaine and morphine self-administration: effects of differential rearing.
Topics: Animals; Body Weight; Cocaine; Drinking; Environment; Male; Morphine; Rats; Self Medication; Time Factors | 1976 |
Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro.
Topics: Biological Transport; Choline; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Mechlorethamine; Morphine | 1976 |
Experience in the identification of abuse drugs in urines collected under Treatment Alternatives to Street Crime.
Topics: Amphetamine; Barbiturates; Charcoal; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Crime; Electronic Data Processing; Forensic Medicine; Humans; Mass Screening; Methadone; Methamphetamine; Morphine; Pharmaceutical Preparations; Spectrometry, Fluorescence; Substance-Related Disorders | 1975 |
[The effect of psychotropic substances on the mental and physical work capacity of rats].
Topics: Amphetamine; Animals; Benactyzine; Caffeine; Chlordiazepoxide; Cocaine; Diazepam; Disability Evaluation; Electric Stimulation; Learning; Male; Meprobamate; Morphine; Phenobarbital; Psychotropic Drugs; Rats; Reinforcement, Psychology; Self Stimulation; Stimulation, Chemical; Work Capacity Evaluation | 1975 |
Ligand-exchange chromatography of alkaloids.
Topics: Alkaloids; Atropine; Chromatography, Ion Exchange; Cinchona; Cinchona Alkaloids; Cocaine; Codeine; Copper; Hydrolysis; Ion Exchange Resins; Methadone; Methods; Morphine; Noscapine; Papaverine; Plants, Medicinal; Quinine; Strychnine | 1975 |
Rapid screening of street drugs by high pressure liquid chromatography: the screening of cocaine, heroin, methadone and morphine by reverse phase HPLC.
Topics: Chromatography, High Pressure Liquid; Cocaine; Heroin; Methadone; Morphine | 1975 |
Perinatal narcotic addiction in mice: sensitization to morphine stimulation.
Topics: Age Factors; Animals; Animals, Newborn; Cocaine; Cycloheximide; Dextroamphetamine; Dextrorphan; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Synergism; Female; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Levorphanol; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Morphine; Motor Activity; Naloxone; Species Specificity; Substance-Related Disorders; Time Factors | 1975 |
[Dependence on and preference for morphine. (III) Improvement of spontaneous drug intake after combined treatment with morphine and cocaine].
Topics: Animals; Cocaine; Codeine; Humans; Male; Morphine; Morphine Dependence; Quinine; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1975 |
Current research in the indoleamine hypothesis of affective disorders.
Topics: Affective Symptoms; Animals; Bipolar Disorder; Brain; Cocaine; Humans; Indoles; Lithium; Male; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1975 |
Letter: Drug screening for employment purposes: the importance of telling it like it is.
Topics: Chromatography, Thin Layer; Cocaine; Evaluation Studies as Topic; False Positive Reactions; Female; Humans; Morphine; Occupational Medicine; Quinine | 1976 |
Effect of murine retroviral infection on hair and serum levels of cocaine and morphine.
Topics: Age Factors; Animals; Cocaine; Disease Models, Animal; Female; Hair; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Morphine; Radioimmunoassay; Retroviridae Infections | 1992 |
Potentiation of opioid analgesia by cocaine: the role of spinal and supraspinal receptors.
Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Morphine; Receptors, Opioid; Spinal Cord | 1992 |
Fischer and Lewis rat strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system.
Topics: Animals; Brain; Cocaine; Cytoskeletal Proteins; Dopamine; Limbic System; Male; Morphine; Neurofilament Proteins; Rats; Rats, Inbred F344; Rats, Inbred Lew; Self Administration; Tegmentum Mesencephali; Time Factors; Tissue Distribution; Tyrosine 3-Monooxygenase | 1992 |
Neurofilament proteins and the mesolimbic dopamine system: common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area.
Topics: Animals; Cocaine; Cytoskeletal Proteins; Dopamine; Limbic System; Male; Molecular Weight; Morphine; Neurofilament Proteins; Phosphoproteins; Psychotropic Drugs; Rats; Rats, Inbred Strains; Rosaniline Dyes; Staining and Labeling; Stress, Physiological; Tegmentum Mesencephali; Time Factors | 1992 |
Discriminative stimulus properties of cocaine, alone and in combination with buprenorphine, morphine and naltrexone.
Topics: Animals; Buprenorphine; Cocaine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Combinations; Male; Morphine; Naltrexone; Rats; Sodium Chloride | 1992 |
Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Male; Morphine; Naloxone; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1992 |
Enhancement of morphine-induced analgesia and attenuation of morphine-induced side-effects by cocaine in rats.
Topics: Analgesia; Animals; Body Temperature; Cocaine; Drug Synergism; Heart Rate; Male; Morphine; Motor Activity; Pain Measurement; Rats; Rats, Wistar; Regional Blood Flow; Respiration; Skin | 1992 |
Assessment of the ambulation-increasing effect of ketamine by coadministration with central-acting drugs in mice.
Topics: alpha-Methyltyrosine; Animals; Caffeine; Central Nervous System Agents; Central Nervous System Depressants; Ceruletide; Cocaine; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methamphetamine; Methyltyrosines; Mice; Morphine; Motor Activity; Neurotransmitter Uptake Inhibitors; Nimodipine; Piperazines; Scopolamine | 1992 |
[Significance of drug determination in pilocarpine sweat for detection of past drug abuse].
Topics: Adult; Cocaine; Female; Humans; Illicit Drugs; Male; Methadone; Morphine; Pilocarpine; Psychotropic Drugs; Substance Abuse Detection; Sweat; Time Factors | 1992 |
Cigarette, alcohol, and other drug use by school-age pregnant adolescents: prevalence, detection, and associated risk factors.
Topics: Adolescent; Alcohol Drinking; Attitude to Health; Baltimore; Breath Tests; Cannabinoids; Carbon Monoxide; Cocaine; Female; Health Behavior; Humans; Interpersonal Relations; Logistic Models; Marijuana Smoking; Morphine; Pregnancy; Pregnancy in Adolescence; Pregnancy Trimester, Third; Prevalence; Risk Factors; Smoking; Substance Abuse Detection; Substance-Related Disorders | 1992 |
Calcium antagonists isradipine and nimodipine suppress cocaine and morphine intravenous self-administration in drug-naive mice.
Topics: Animals; Calcium Channel Blockers; Cocaine; Dihydropyridines; Dopamine; Injections, Intravenous; Isradipine; Mice; Morphine; Nimodipine; Reinforcement, Psychology; Reward; Self Administration | 1992 |
The cardiovascular and subjective effects of intravenous cocaine and morphine combinations in humans.
Topics: Adult; Blood Pressure; Cocaine; Drug Combinations; Heart Rate; Humans; Injections, Intravenous; Male; Morphine; Psychomotor Performance; Surveys and Questionnaires | 1992 |
The effect of morphine and naloxone on cocaine toxicity.
Topics: Animals; Cocaine; Death; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Seizures | 1992 |
Dramatic depletion of mesolimbic extracellular dopamine after withdrawal from morphine, alcohol or cocaine: a common neurochemical substrate for drug dependence.
Topics: Alcoholism; Animals; Cocaine; Dopamine; Limbic System; Morphine; Morphine Dependence; Neurons; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1992 |
Ion-trap mass spectrometry applications in forensic sciences. I. Identification of morphine and cocaine in hair extracts of drug addicts.
Topics: Cocaine; Forensic Medicine; Hair; Humans; Mass Spectrometry; Morphine; Substance-Related Disorders | 1992 |
The partial opioid agonist, buprenorphine, protects against lethal effects of cocaine.
Topics: Animals; Brain; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; Methadone; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Receptors, Opioid; Receptors, Opioid, mu; Seizures | 1991 |
A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function.
Topics: Adenylyl Cyclases; Animals; Brain; Cells, Cultured; Cocaine; Cyclic AMP; Drug Administration Schedule; Ganglia, Spinal; GTP-Binding Proteins; Male; Models, Neurological; Morphine; Morphine Dependence; Neurons; Organ Specificity; Protein Kinases; Rats; Rats, Inbred Strains; Spinal Cord; Substance-Related Disorders | 1991 |
Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions.
Topics: Animals; Cocaine; Dopamine; Male; Morphine; Nucleus Accumbens; Phosphorylation; Rats; Rats, Inbred Strains; Reward; Tegmentum Mesencephali; Time Factors; Tyrosine 3-Monooxygenase | 1991 |
Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Cocaine; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Dopamine Agents; Drug Synergism; Ergolines; Generalization, Psychological; Haloperidol; Lead; Male; Morphine; N-Methylaspartate; Pentobarbital; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine- and cocaine-regulated phosphoproteins.
Topics: Animals; Brain; Cocaine; Dopamine; Genotype; Morphine; Phosphoproteins; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reward; Tyrosine 3-Monooxygenase | 1991 |
Modulation of tumor necrosis factor and gamma interferon production by cocaine and morphine in aging mice infected with LP-BM5, a murine retrovirus.
Topics: Aging; Animals; Cocaine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Interferons; Mice; Mice, Inbred C57BL; Morphine; Murine Acquired Immunodeficiency Syndrome; Retroviridae; Retroviridae Infections; Spleen; Tumor Necrosis Factor-alpha | 1991 |
Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study.
Topics: Cannabis; Cocaine; Female; Humans; Infant, Newborn; Marijuana Abuse; Mass Screening; Meconium; Morphine; Morphine Dependence; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Sensitivity and Specificity; Substance-Related Disorders; United States | 1992 |
Accuracy, precision, and interferences of three modified EMIT procedures for determining serum phenobarbital, urine morphine, and urine cocaine metabolite with a Cobas-Fara.
Topics: Autoanalysis; Cocaine; Humans; Immunoenzyme Techniques; Morphine; Phenobarbital | 1991 |
Intravenous self-administration of an enkephalin analog, EK-399, by rats.
Topics: Analgesics; Animals; Behavior, Animal; Cocaine; Enkephalins; Infusions, Intravenous; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1991 |
Establishment of chronic intravenous drug self-administration in the C57BL/6J mouse.
Topics: Animals; Cocaine; Disease Models, Animal; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Pentobarbital; Self Administration; Species Specificity; Substance-Related Disorders | 1991 |
A case of high opiate tolerance: implications for drug analyses and interpretations.
Topics: Automobile Driving; Cocaine; Ethylmorphine; Forensic Medicine; Humans; Morphine; Substance-Related Disorders | 1991 |
Immune status and survival of opiate- and cocaine-treated mice infected with Friend virus.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibody Formation; Cocaine; Drug Tolerance; Friend murine leukemia virus; Hemagglutination Tests; Hypersensitivity, Delayed; Immunity, Cellular; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Morphine; Pentazocine; Substance-Related Disorders | 1991 |
Splenocyte subsets in normal and protein malnourished mice after long-term exposure to cocaine or morphine.
Topics: Animals; Antigens, Surface; Cocaine; Disease Models, Animal; Female; Leukocyte Count; Lymphocyte Subsets; Macrophages; Mice; Mice, Inbred C57BL; Morphine; Nutrition Disorders; Organ Size; Spleen; Substance-Related Disorders | 1991 |
The effects of cocaine in combination with other drugs of abuse on schedule-controlled behavior in the pigeon.
Topics: Animals; Caffeine; Cocaine; Columbidae; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Illicit Drugs; Male; Morphine; Reinforcement Schedule | 1990 |
Performance of techniques used to detect drugs of abuse in urine: study based on external quality assessment.
Topics: Amphetamine; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; False Positive Reactions; Humans; Immunoassay; Methadone; Morphine; Quality Control | 1991 |
Skeletal muscle as an alternative specimen for alcohol and drug analysis.
Topics: Antidepressive Agents, Tricyclic; Benzodiazepines; Cocaine; Codeine; Dextropropoxyphene; Ethanol; Humans; Morphine; Muscles; Pharmaceutical Preparations; Postmortem Changes; Vitreous Body | 1991 |
The role of the olfactory tubercle in the effects of cocaine, morphine and brain-stimulation reward.
Topics: Animals; Brain; Cocaine; Electric Stimulation; Glucose; Male; Morphine; Olfactory Bulb; Rats; Rats, Inbred F344; Reward; Sodium Chloride; Tissue Distribution | 1991 |
The ambulation-increasing effect of buprenorphine in mice: comparison with the effect of morphine.
Topics: Animals; Buprenorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Morphine; Naloxone; Pilocarpine; Scopolamine | 1991 |
[Characteristics of antagonism between ceruletide and various central-acting drugs: investigation by means of ambulatory activity in mice].
Topics: Animals; Bromocriptine; Caffeine; Ceruletide; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Ephedrine; Haloperidol; Male; Methamphetamine; Methylphenidate; Mice; Morphine; Motor Activity; Scopolamine | 1990 |
[A new system for the measurement and analysis of motor activity in mice: effect of several central stimulants].
Topics: Animals; Apomorphine; Behavioral Sciences; Caffeine; Cocaine; Dose-Response Relationship, Drug; Male; Methamphetamine; Mice; Morphine; Motor Activity | 1990 |
Effects of cocaine and morphine on IgG production by human peripheral blood lymphocytes in vitro.
Topics: Acquired Immunodeficiency Syndrome; B-Lymphocytes; Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Morphine; Pokeweed Mitogens; Substance Abuse, Intravenous | 1990 |
Hair analysis.
Topics: Animals; Cocaine; Hair; Humans; Male; Mice; Morphine; Substance Abuse Detection | 1990 |
Behavioral effects of cocaine and its interaction with d-amphetamine and morphine in rats.
Topics: Amphetamines; Animals; Behavior, Animal; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Morphine; Reinforcement, Psychology | 1990 |
Dose-response inhibition of rat compound nerve action potential by dextropropoxyphene and codeine compared to morphine and cocaine in vitro.
Topics: Action Potentials; Animals; Cocaine; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Morphine; Neural Conduction; Neurons; Rats; Rats, Inbred Strains | 1990 |
Mechanism of false-negative urine cannabinoid immunoassay screens by Visine eyedrops.
Topics: Amphetamine; Benzalkonium Compounds; Cannabinoids; Cocaine; Dronabinol; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Morphine; Nasal Decongestants; Oxazepam; Phencyclidine; Secobarbital; Ultrafiltration | 1989 |
Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine.
Topics: Amphetamine; Animals; Chlorides; Cocaine; Conditioning, Operant; Lithium; Lithium Chloride; Male; Morphine; Rats; Rats, Inbred Strains; Reward | 1989 |
Behavioral and EEG studies of acute cocaine administration: comparisons with morphine, amphetamine, pentobarbital, nicotine, ethanol and marijuana.
Topics: Adult; Affect; Alpha Rhythm; Amphetamine; Arousal; Cerebral Cortex; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Electroencephalography; Ethanol; Euphoria; Female; Humans; Male; Morphine; Nicotine; Pentobarbital; Signal Processing, Computer-Assisted | 1989 |
Comparison of drug abuse in different military populations.
Topics: Amphetamines; Cocaine; Codeine; Humans; Marijuana Smoking; Military Personnel; Morphine; Radioimmunoassay; Substance-Related Disorders; United States | 1989 |
Drug screening of meconium in infants of drug-dependent mothers: an alternative to urine testing.
Topics: Animals; Cannabinoids; Cocaine; Feces; Female; Heroin; Humans; Infant, Newborn; Mass Screening; Maternal-Fetal Exchange; Meconium; Morphine; Predictive Value of Tests; Pregnancy; Psychotropic Drugs; Rats; Rats, Inbred Strains; Substance-Related Disorders | 1989 |
Enhancement of ambulation-increasing effect of methamphetamine by peripherally-administered 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (R-THBP) in mice.
Topics: Animals; Biopterins; Bromocriptine; Cocaine; Drug Synergism; Ephedrine; Male; Mazindol; Methamphetamine; Mice; Morphine; Motor Activity; Scopolamine; Time Factors | 1989 |
Blockade of tolerance to morphine analgesia by cocaine.
Topics: Analgesics; Animals; Cocaine; Drug Implants; Drug Tolerance; Male; Morphine; Pain; Rats; Rats, Inbred Strains | 1989 |
Interactive toxicity of cocaine with phenobarbital, morphine and ethanol in organ cultured human and rat liver slices.
Topics: Animals; Calcium; Chemical and Drug Induced Liver Injury; Cocaine; Drug Interactions; Ethanol; Humans; Liver; Male; Morphine; Organ Culture Techniques; Phenobarbital; Potassium; Rats; Rats, Inbred Strains | 1989 |
[Diaplacental poisoning with narcotics and alcohol in newborn infants].
Topics: Amphetamine; Cause of Death; Cocaine; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Maternal-Fetal Exchange; Morphine; Neonatal Abstinence Syndrome; Pregnancy | 1989 |
Neuroleptics block the positive reinforcing effects of amphetamine but not of morphine as measured by place conditioning.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Drug Interactions; Flupenthixol; Male; Morphine; Orientation; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward | 1985 |
[Methodology and problems in the study of drugs of abuse in urine].
Topics: Amphetamines; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Cannabinoids; Chromatography; Cocaine; Heroin; Heroin Dependence; Humans; Illicit Drugs; Immunologic Techniques; Morphine; Morphine Dependence; Pharmaceutical Preparations; Specimen Handling; Substance-Related Disorders | 1986 |
Detection of drugs in the urine of body-packers.
Topics: Cocaine; Crime; Evaluation Studies as Topic; Foreign Bodies; Foreign-Body Migration; Heroin; Humans; Immunoenzyme Techniques; Morphine; Radiography; Rectum | 1988 |
Crisis in drug testing. Results of CDC blind study.
Topics: Amphetamines; Barbiturates; Centers for Disease Control and Prevention, U.S.; Cocaine; Codeine; Diagnostic Errors; Humans; Illicit Drugs; Laboratories; Methadone; Morphine; Pharmaceutical Preparations; Quality Control; Research Design; United States | 1985 |
Maternal-fetal transfer of abused substances: pharmacokinetic and pharmacodynamic data.
Topics: Amphetamine; Animals; Cocaine; Dronabinol; Female; Fetus; Humans; Kinetics; Lysergic Acid Diethylamide; Maternal-Fetal Exchange; Meperidine; Methadone; Morphine; Nicotine; Phencyclidine; Pregnancy; Substance-Related Disorders | 1985 |
Drug discrimination procedures: differential characteristics of the drug A vs drug B and the drug A vs drug B vs no drug cases.
Topics: Animals; Cocaine; Columbidae; Discrimination Learning; Discrimination, Psychological; Female; Generalization, Psychological; Male; Morphine; Psychotropic Drugs | 1986 |
Mode of potentiating action of cocaine in morphine analgesia.
Topics: Analgesia; Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Morphine; Muscle Contraction; Nociceptors; Pentazocine; Rabbits | 1988 |
[Pharmacological interactions between dependence-liable drugs].
Topics: Amphetamine; Animals; Cocaine; Drug Interactions; Drug Tolerance; Ethanol; Male; Mice; Morphine; Pentobarbital; Risk; Substance-Related Disorders | 1988 |
Effects of daily cocaine and morphine treatment on somatodendritic and terminal field dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Cocaine; Corpus Striatum; Dopamine; Male; Mesencephalon; Morphine; Nucleus Accumbens; Potassium; Rats; Rats, Inbred Strains | 1988 |
Modification of the response to opioid and nonopioid drugs by chronic opioid antagonist treatment.
Topics: Alprazolam; Analgesia; Animals; Ataxia; Cocaine; Drug Implants; Kinetics; Male; Methadone; Mice; Morphine; Naloxone; Narcotics | 1988 |
Cross reverse tolerance between amphetamine, cocaine and morphine.
Topics: Animals; Cocaine; Dextroamphetamine; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Swimming | 1987 |
Mapping the cerebral distributions of action of euphoriant drugs.
Topics: Animals; Autoradiography; Brain; Cocaine; Glucose; Male; Morphine; Nicotine; Phencyclidine; Rats; Rats, Inbred F344; Tissue Distribution | 1986 |
Studies on the effects of the narcotic alkaloids, cocaine, morphine, and codeine on nonenzymatic lipid peroxidation in rat brain mitochondria.
Topics: Alkaloids; Animals; Ascorbic Acid; Brain; Cocaine; Codeine; Lipid Peroxides; Male; Malondialdehyde; Mitochondria; Morphine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1987 |
Morphine discrimination in the pigeon using a color tracking procedure.
Topics: Animals; Cocaine; Color; Columbidae; Cues; Cyclazocine; Dextroamphetamine; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Response; Male; Meperidine; Methadone; Morphine; Narcotics; Pentobarbital; Phencyclidine; Psychomotor Performance | 1986 |
Drug discrimination procedures: roles of relative stimulus control in two-drug cases.
Topics: Animals; Apomorphine; Cocaine; Columbidae; Discrimination Learning; Generalization, Psychological; Lysergic Acid Diethylamide; Morphine; Pentobarbital | 1985 |
Brain-stimulation reward: a model for the neuronal bases for drug-induced euphoria.
Topics: Animals; Brain; Cocaine; Dextroamphetamine; Electric Stimulation; Euphoria; Humans; Models, Neurological; Morphine; Nalbuphine; Neural Pathways; Neurons; Rats; Reward; Self Stimulation; Substance-Related Disorders; Tripelennamine | 1985 |
Characteristics of tolerance, recovery from tolerance and cross-tolerance for cocaine used as a discriminative stimulus.
Topics: Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Male; Morphine; Rats; Time Factors | 1986 |
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine.
Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine | 1972 |
Letter: Unusual cardiac and neurological reactions to narcotics.
Topics: Adult; Brain; Cocaine; Demyelinating Diseases; Electrocardiography; Heroin; Heroin Dependence; Humans; Infarction; Male; Morphine; Myelitis; Myelitis, Transverse; Myocardial Infarction; Paralysis; Substance-Related Disorders | 1973 |
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium | 1974 |
Electrically induced contractions of guinea-pig isolated ileum resistant to tetrodotoxin.
Topics: Acetylcholine; Animals; Cocaine; Cold Temperature; Drug Resistance; Electric Stimulation; Guinea Pigs; Histamine H1 Antagonists; Hypoxia; Ileum; In Vitro Techniques; Lidocaine; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Phloretin; Potassium Chloride; Prostaglandins; Scopolamine; Serotonin Antagonists; Tetrodotoxin | 1973 |
Urine screening techniques employed in the detection of users of narcotics and their correlation with the nalorphine test.
Topics: Amphetamine; California; Cocaine; Codeine; Humans; Hydromorphone; Meperidine; Methadone; Morphine; Nalorphine; Pupil; Substance-Related Disorders | 1966 |
Heroin and cocaine addiction.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Cocaine; Dextroamphetamine; Ethanol; Female; Follow-Up Studies; Heroin; Hospitalization; Hospitals, Psychiatric; Humans; Injections, Intravenous; Male; Methadone; Morphine; Substance Withdrawal Syndrome; Substance-Related Disorders; United Kingdom; United States | 1965 |
Motility in Pseudomonas fluorescens with special reference to survival advantage and negative chemotaxis.
Topics: Acetylcholine; Amobarbital; Chemotaxis; Chloramphenicol; Cocaine; Culture Media; Dicumarol; Dimethyl Sulfoxide; Flagella; Indoleacetic Acids; Locomotion; Microscopy, Phase-Contrast; Morphine; Phenols; Phenylalanine; Physostigmine; Pseudomonas; Pyridinium Compounds; Quinacrine; Strychnine; Surface-Active Agents; Urea | 1968 |
On the electroencephalogram of man. Thirteenth report.
Topics: Adult; Atropine; Bipolar Disorder; Caffeine; Cerebral Cortex; Cocaine; Electroencephalography; Female; Germany; Heart Rate; History, 20th Century; Humans; Male; Methods; Morphine; Psychophysiology; Pulse; Stimulation, Chemical; Time Factors | 1969 |
The effects of stimulants and depressants on cocaine self-administration behavior in the rhesus monkey.
Topics: Animals; Cocaine; Exploratory Behavior; Grooming; Haplorhini; Imipramine; Locomotion; Macaca; Male; Morphine; Motor Activity; Pentobarbital; Phenmetrazine; Self Medication; Trifluoperazine | 1973 |
A comparison of chlorpromazine, imipramine, morphine and d-amphetamine self-administration in cocaine-dependent rhesus monkeys.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Haplorhini; Humans; Imipramine; Macaca; Morphine; Self Stimulation; Substance-Related Disorders | 1973 |
Negative reinforcing properties of morphine-antagonists in naive rhesus monkeys.
Topics: Animals; Avoidance Learning; Cocaine; Codeine; Conditioning, Classical; Cyclazocine; Escape Reaction; Female; Haplorhini; Macaca; Male; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Pentazocine; Piperidines; Propionates; Pyridines; Reinforcement, Psychology | 1973 |
Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Culture Media; Deamination; Dopamine; Edetic Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Lidocaine; Methacholine Compounds; Methylation; Morphine; Nicotine; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Rats; Tritium | 1974 |
[On the pharmacology of 2-(2,6-dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazine (Bayer 1470), a substance inhibitory for adrenergic and cholinergic neurons].
Topics: Analgesics; Animals; Antacids; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Bretylium Compounds; Cats; Cocaine; Gastric Juice; Guanethidine; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Mice; Morphine; Muscles; Nictitating Membrane; Parasympatholytics; Rabbits; Sympatholytics; Sympathomimetics; Thiazines | 1967 |
Self-administration of d-amphetamine, morphine and chlorpromazine by cocaine "dependent" rhesus monkeys.
Topics: Animals; Behavior, Animal; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Extinction, Psychological; Haplorhini; Humans; Morphine; Reinforcement, Psychology; Substance-Related Disorders | 1970 |
Studies on the transport of morphine out of the perfused cerebral ventricles of rabbits.
Topics: Aminohippuric Acids; Animals; Biological Transport; Cerebral Ventricles; Cisterna Magna; Cocaine; Codeine; Diffusion; Dinitrophenols; Male; Morphine; Naloxone; Niacinamide; Osmolar Concentration; Ouabain; Perfusion; Quinine; Rabbits; Stereotaxic Techniques; Time Factors | 1972 |
Observations on the ganglion-stimulating action of angiotensin and bradykinin.
Topics: Angiotensin II; Animals; Bradykinin; Cats; Cocaine; Ganglia, Autonomic; Hexamethonium Compounds; Morphine; Nicotine; Nictitating Membrane | 1966 |
The origin of acetylcholine released from guinea-pig intestine and longitudinal muscle strips.
Topics: Acetylcholine; Animals; Cocaine; Diabetes Mellitus, Experimental; Electric Stimulation; Female; Guinea Pigs; Ileum; Insulin; Male; Morphine; Muscle Denervation; Muscle, Smooth; Myenteric Plexus; Parasympathomimetics; Physostigmine; Rats; Synaptic Transmission | 1968 |
Angiotensin in the analysis of the intrinsic nerve supply of isolated intestines.
Topics: Angiotensin II; Animals; Atropine; Cocaine; Epinephrine; Gerbillinae; Hexamethonium Compounds; Ileum; Intestines; Mecamylamine; Mice; Morphine; Motor Neurons; Muscle Contraction; Muscle, Smooth; Papaverine; Pentolinium Tartrate; Procaine; Rats | 1968 |
The pharmacological basis of drug dependence.
Topics: Amphetamine; Barbiturates; Cannabis; Central Nervous System; Cocaine; Ethanol; Hallucinogens; Heroin; Humans; Morphine; Nicotine; Pharmacology; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission | 1970 |
Choline acetyltransferase and acetylcholinesterase in cultured brain cells from chick embryos.
Topics: Acetylcholinesterase; Acyltransferases; Ammonia; Animals; Brain; Centrifugation; Chick Embryo; Cocaine; Creatine Kinase; Culture Techniques; Cyclic AMP; DNA; Fluorouracil; Histocytochemistry; Microscopy, Phase-Contrast; Morphine; Nerve Tissue Proteins; Spectrophotometry; Theophylline; Thyroxine | 1971 |
Effect of 9 - and 8 -tetrahydrocannabinol on the peripheral autonomic nervous system in vitro.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Autonomic Nervous System; Barium; Cannabis; Cocaine; Diaphragm; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Drug Synergism; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Peripheral Nerves; Phrenic Nerve; Vas Deferens | 1973 |
Homogenous immunochemical drug assays.
Topics: Amphetamine; Antigen-Antibody Reactions; Barbiturates; Binding Sites, Antibody; Cocaine; Electron Spin Resonance Spectroscopy; Glucuronates; Heroin; Humans; Immunoassay; Methadone; Methods; Morphine; Muramidase; Pharmaceutical Preparations; Spectrophotometry; Substance-Related Disorders | 1973 |
Application of drug-receptor theories to angiotensin.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Atropine; Cocaine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Indomethacin; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Peptides; Phentolamine; Prostaglandins; Rabbits; Rats; Receptors, Cell Surface; Receptors, Drug; Serotonin; Stomach; Structure-Activity Relationship | 1973 |
Experiences with ESR as a tool for surveying narcotic addiction.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Chromatography, Thin Layer; Cocaine; Codeine; Electron Spin Resonance Spectroscopy; Evaluation Studies as Topic; Glucuronates; Heroin; Humans; Mass Screening; Methadone; Methods; Morphine; Rabbits; Saliva; Spin Labels; Substance-Related Disorders; Time Factors | 1973 |
A thin-layer chromatographic procedure for the separation of aspirin, cocaine, caffeine, codeine, heroin, 6-monoacetyl morphine, and morphine.
Topics: Aspirin; Caffeine; Chromatography, Thin Layer; Cocaine; Codeine; Gels; Heroin; Methods; Morphinans; Morphine; Silicon Dioxide; Solvents | 1974 |
Dissociation of 5-hydroxytryptamine effects on myocardial contractility and cyclic AMP accumulation.
Topics: Adenine; Animals; Carbon Radioisotopes; Cocaine; Cyclic AMP; Dihydroergotamine; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Hydroxydopamines; In Vitro Techniques; Male; Morphine; Myocardium; Norepinephrine; Phenoxybenzamine; Proteins; Rats; Reserpine; Serotonin; Stimulation, Chemical; Tritium; Tyramine | 1974 |
The stimulation of canine prostatic secretion by pilocarpine.
Topics: Animals; Cocaine; Dogs; Ethanolamines; Hexamethonium Compounds; Male; Morphine; Phenoxybenzamine; Pilocarpine; Prostate; Reserpine; Secretory Rate; Semen; Sympatholytics | 1966 |
Effect of gastrin on isolated smooth muscle preparation.
Topics: Acetylcholine; Animals; Cocaine; Colon; Female; Gastrins; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Hypoxia; Intestine, Small; Methysergide; Morphine; Muscle, Smooth; Physostigmine; Piperazines; Rats; Scopolamine; Serotonin; Stomach; Uterus | 1965 |
Potentiation of the anticonvulsant action of acetazolamide.
Topics: Acetazolamide; Amphetamine; Animals; Anticonvulsants; Caffeine; Cocaine; Desipramine; Drug Synergism; Electric Stimulation; Electroshock; Ephedrine; Histamine H1 Antagonists; Imipramine; Isoproterenol; Male; Metaraminol; Mice; Morphine; Phenethylamines; Quaternary Ammonium Compounds; Seizures; Stress, Physiological; Tranylcypromine; Tyramine | 1966 |
The site of action of drugs on the isolated taenia caeci from the guinea-pig.
Topics: Acetylcholine; Animals; Cecum; Cocaine; Female; Guinea Pigs; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Insecticides; Lysergic Acid Diethylamide; Male; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Piperazines; Procaine; Scopolamine; Serotonin; Sympathomimetics | 1966 |
Mechanisms of sympathomimetic effects of dichloroisoproterenol: comparison with tyramine, nicotine and norepinephrine.
Topics: Animals; Atropine; Cocaine; Diaphragm; Drug Antagonism; Ganglionic Blockers; Guanidines; Heart; Heart Atria; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Iproniazid; Isoproterenol; Morphine; Nicotine; Norepinephrine; Pentolinium Tartrate; Phenoxybenzamine; Propranolol; Rats; Sympatholytics; Tranylcypromine; Tyramine | 1967 |
Mechanism of radiation-induced granulocytosis.
Topics: Animals; Cocaine; Drug Antagonism; Epinephrine; Histamine; Histamine H1 Antagonists; Leukocytes; Lysergic Acid Diethylamide; Morphine; Neutrophils; Norepinephrine; Phenoxybenzamine; Radiation Effects; Rats; Serotonin | 1967 |
Species difference in the inhibition of drug metabolism by liver microsomes by different inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cocaine; Depression, Chemical; Drug Antagonism; Ethylamines; Hexobarbital; Histamine H1 Antagonists; Kinetics; Male; Meperidine; Mice; Microsomes, Liver; Morphine; Nitrophenols; Oxidation-Reduction; Pentobarbital; Pharmaceutical Preparations; Phenacetin; Phenylhydrazines; Piperazines; Proadifen; Rabbits; Rats; Species Specificity; Zoxazolamine | 1969 |
On the role of a central adrenergic mechanism in morphine analgesic action.
Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1969 |
Analgesic activity of some sympathetic drugs and their effect on morphine analgesia in rabbits.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analgesia; Animals; Brain; Cocaine; Desipramine; Dopamine; Drug Synergism; Electric Stimulation; Epinephrine; Guanethidine; Isoproterenol; Male; Methoxamine; Methyltyrosines; Morphine; Norepinephrine; Nortriptyline; Pain; Phenoxybenzamine; Rabbits; Sympathomimetics | 1969 |
The pharmacology of isolated sheep umbilical cord blood vessels.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Atropine; Bromine; Catecholamines; Cocaine; Epinephrine; Ergolines; Ergonovine; Ergot Alkaloids; Ergotamine; Female; In Vitro Techniques; Isoproterenol; Lysergic Acid Diethylamide; Morphine; Muscle Contraction; Norepinephrine; Peptides; Pregnancy; Serotonin; Sheep; Sympatholytics; Umbilical Arteries; Umbilical Veins | 1970 |
[Potentiating effects of choline on the action of phenyl acetate. 5. Effects of inhibitors of acetylcholine liberation].
Topics: Acetylcholine; Animals; Choline; Cocaine; Cold Temperature; Drug Synergism; Electric Stimulation; Epinephrine; Ganglionic Blockers; Guinea Pigs; Hemicholinium 3; Histamine; Ileum; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Oxygen; Phenylacetates; Picrates; Piperazines; Procaine; Strychnine; Tetrodotoxin | 1971 |
The role of brain catecholamines in morphine analgesic action in morphine tolerant rats.
Topics: Amphetamine; Analgesics; Animals; Brain; Catecholamines; Cocaine; Disulfiram; Drug Synergism; Drug Tolerance; Female; Iproniazid; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1970 |
The action of choline on the superior cervical ganglion of the cat.
Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Cats; Choline; Cocaine; Denervation; Dimethylphenylpiperazinium Iodide; Drug Synergism; Electric Stimulation; Female; Ganglia, Autonomic; Ganglionic Blockers; Ganglionic Stimulants; Hexamethonium Compounds; Male; Methadone; Morphine; Nicotine; Nictitating Membrane; Sensory Receptor Cells | 1972 |
Contraction of the urinary bladder by muscarinic ganglionic stimulants: possible existence of muscarinic receptor sites on its parasympathetic ganglia.
Topics: Alkynes; Animals; Atropine; Benzyl Compounds; Blood Pressure; Carbamates; Cats; Cocaine; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Ganglia, Autonomic; Ganglionic Blockers; Ganglionic Stimulants; Guanethidine; Laparotomy; Morphine; Muscle Contraction; Parasympathomimetics; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, Cholinergic; Receptors, Drug; Urinary Bladder | 1972 |
The effect of dopamine on peripheral vasculature of the rat.
Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine | 1972 |
Inhibitory effect of certain drugs on NADH dehydrogenase of mouse heart homogenates.
Topics: Animals; Chloral Hydrate; Cocaine; Cytochrome c Group; Cytochrome Reductases; Dextroamphetamine; Electron Transport Complex IV; Ephedrine; Fenfluramine; In Vitro Techniques; Mice; Morphine; Myocardium; NADH, NADPH Oxidoreductases; Oxidoreductases; Pentobarbital; Procainamide; Procaine; Propranolol; Propylamines | 1973 |
Optimization of extraction and separation of narcotics from urine.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors | 1974 |
Radioimmunoassay: its application to drugs of abuse.
Topics: Amphetamine; Animals; Antibody Formation; Antigen-Antibody Complex; Antigen-Antibody Reactions; Barbiturates; Body Fluids; Cocaine; Dronabinol; Humans; Lysergic Acid Diethylamide; Methadone; Morphine; Pentobarbital; Radioimmunoassay; Radioisotopes; Substance-Related Disorders | 1974 |
[Role of the lungs in the inactivation of serotonin].
Topics: Animals; Body Temperature; Cocaine; Cyanides; Imipramine; Iodoacetates; Lung; Lysergic Acid Diethylamide; Monoamine Oxidase Inhibitors; Morphine; Potassium; Rats; Serotonin; Time Factors | 1974 |
Fatal cocaine poisoning.
Topics: Adult; Child; Cocaine; Female; Forensic Medicine; Humans; Male; Morphine | 1974 |
Discriminative response control produced with hashish, tetrahydrocannabinols (delta 8-THC and delta 9-THC), and other drugs.
Topics: Amphetamine; Animals; Atropine; Avoidance Learning; Cannabis; Chlordiazepoxide; Chlorpromazine; Choice Behavior; Cocaine; Cues; Diazepam; Discrimination, Psychological; Dronabinol; Ketamine; Levallorphan; Male; Morphine; Pentobarbital; Phencyclidine; Physostigmine; Psilocybin; Rats; Scopolamine; Transfer, Psychology; Yohimbine | 1974 |
The effect of pH changes on the precipitating action of tannic acid on alkaloids.
Topics: Alkaloids; Atropine; Chemical Precipitation; Cocaine; Humans; Hydrogen-Ion Concentration; Hydrolyzable Tannins; Morphine; Tannins | 1974 |
Changes in heroin self-administration by a rhesus monkey after morphine immunisation.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Cocaine; Conditioning, Operant; Extinction, Psychological; Freund's Adjuvant; Heroin; Heroin Dependence; Humans; Immunization; Immunoglobulin G; Macaca; Morphine; Serum Albumin | 1974 |
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Eye Movements; Humans; Levallorphan; Male; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Nasal Mucosa; Norepinephrine; Piperazines; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Cell Line; Cells, Cultured; Choline; Cocaine; Cyclopentanes; Diazepam; Glucose; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Mice; Morphine; Phenobarbital; Stimulation, Chemical | 1974 |
Drugs of abuse: legal and illegal.
Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Drug and Narcotic Control; Drug Contamination; Hallucinogens; Heroin; History, 19th Century; History, 20th Century; History, Ancient; Humans; Laboratories; Military Personnel; Morphine; Narcotics; Opium; Smoking; Substance-Related Disorders | 1972 |
Reinforcing properties of some opiates and opioids in rhesus monkeys with histories of cocaine and codeine self-administration.
Topics: Amides; Analgesics; Animals; Cocaine; Codeine; Conditioning, Psychological; Dextropropoxyphene; Female; Fumarates; Haplorhini; Injections, Intravenous; Macaca; Male; Morphine; Nalorphine; Pentazocine; Piperidines; Propionates; Reinforcement, Psychology | 1972 |
Drug abuse: detection, guidelines, and policies.
Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Hallucinogens; Humans; Lysergic Acid Diethylamide; Morphine; Occupational Medicine; Personnel Administration, Hospital; Psychoses, Substance-Induced; Substance-Related Disorders | 1972 |
Stability of certain drugs of abuse in urine specimens.
Topics: Amphetamine; Azides; Cocaine; Codeine; Drug Stability; Humans; Methadone; Morphine; Pharmaceutical Preparations; Phenobarbital; Secobarbital; Substance-Related Disorders; Temperature | 1972 |
Simple gas-liquid chromatographic method for confirming the presence of alkaloids in urine.
Topics: 1-Propanol; Chloroform; Chromatography, Gas; Cocaine; Codeine; Methadone; Methods; Morphine; Solubility | 1973 |
Morphine, mescaline and cocaine on water maze discrimination in mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Discrimination Learning; Male; Mescaline; Mice; Morphine | 1973 |
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue.
Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium | 1973 |
Myogenic peristalsis in isolated preparations of chicken oesophagus.
Topics: Acetylcholine; Animals; Chickens; Cocaine; Esophagus; Female; Gastrointestinal Motility; In Vitro Techniques; Male; Methysergide; Morphine; Mucous Membrane; Muscle Contraction; Nicotine; Norepinephrine; Papaverine; Phentolamine; Picrotoxin; Pressure; Propranolol; Rectum; Scopolamine; Stimulation, Chemical; Strychnine; Tetrodotoxin; Tubocurarine; Vagus Nerve | 1973 |
Homicide and LSD.
Topics: Adult; Aggression; Cocaine; Delusions; Drug Interactions; Forensic Psychiatry; Homicide; Humans; Intelligence Tests; Lysergic Acid Diethylamide; Male; Methamphetamine; Morphine; Substance-Related Disorders | 1973 |
The effect of heroin and multiple drug abuse on the electrocardiogram.
Topics: Adolescent; Adult; Alcoholism; Barbiturates; Bradycardia; Cocaine; Death, Sudden; Electrocardiography; Female; Heart; Heart Rate; Heroin; Humans; Male; Methadone; Middle Aged; Morphine; Quinine; Substance-Related Disorders | 1973 |
Psychoactive compounds and audiogenic seizure susceptibility.
Topics: Acoustic Stimulation; Amphetamine; Animals; Bromine; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Tolerance; Lysergic Acid Diethylamide; Mescaline; Mice; Mice, Inbred Strains; Morphine; Mutation; Seizures; Time Factors | 1973 |
Drug use and personal values of high school students.
Topics: Adolescent; Amphetamine; Barbiturates; Cannabis; Cocaine; Female; Hallucinogens; Heroin; Humans; Interpersonal Relations; Male; Morphine; Schools; Social Behavior; Social Values; Students; Substance-Related Disorders; Surveys and Questionnaires; United States | 1973 |
The action of hordenine on the superior cervical ganglion of the cat.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cats; Cocaine; Dimethylamines; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Epinephrine; Female; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Male; Methadone; Morphine; Muscle Contraction; Nicotine; Nictitating Membrane; Phenethylamines; Propranolol; Receptors, Adrenergic; Receptors, Cholinergic; Time Factors | 1973 |
Proceedings: Drug-induced changes in the sensitivity of the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Cocaine; Corticosterone; Drug Synergism; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Norepinephrine; Rats; Reserpine; Thyroxine | 1973 |
[A simple method for the indentification of narcotics].
Topics: Cannabis; Cocaine; Germany, West; Indicators and Reagents; Lysergic Acid Diethylamide; Methods; Morphinans; Morphine; Narcotics; Opium; Reagent Strips | 1973 |
Studies on the use of XAD-2 resin for detection of abused drugs in urine.
Topics: Amobarbital; Amphetamine; Aspirin; Caffeine; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cocaine; Codeine; Evaluation Studies as Topic; Glucuronates; Humans; Hydrolysis; Meperidine; Meprobamate; Mescaline; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Naloxone; Pentobarbital; Secobarbital; Substance-Related Disorders | 1974 |
Induction of hepatic drug metabolizing enzymes by lithium treatment.
Topics: Aniline Compounds; Animals; Carbonates; Cocaine; Dealkylation; Enzyme Induction; Hydroxylation; Lithium; Liver; Morphine; Rats | 1974 |
The inhibition of the uptake of monoamines by blood platelets by phenothiazines and other drugs.
Topics: Animals; Antidepressive Agents; Atropine; Biogenic Amines; Blood Platelets; Carbon Radioisotopes; Cell Membrane; Cocaine; Depression, Chemical; Dibenzazepines; Dopamine; Hemolysis; In Vitro Techniques; Metaraminol; Methadone; Methylation; Morphine; Phenothiazines; Serotonin; Structure-Activity Relationship; Surface Tension; Tritium | 1974 |
Specificity of blockade of the nicotine-induced release of 3H-norepinephrine from adrenergic neurons of the guinea-pig heart by various pharmacological agents.
Topics: Aminophylline; Animals; Bretylium Compounds; Cocaine; Colchicine; Guinea Pigs; Heart; Hexamethonium Compounds; In Vitro Techniques; Lidocaine; Morphine; Myocardium; Neurons; Nicotine; Norepinephrine; Perfusion; Potassium Chloride; Prostaglandins; Stimulation, Chemical; Tritium; Tyramine | 1974 |
The use of modified cellulose papers in routine toxicological analysis. 4. Alkaloids.
Topics: Acetates; Alkaloids; Amphetamine; Atropine; Caffeine; Cellulose; Chromatography, Paper; Cocaine; Codeine; Methylcellulose; Morphine; Papaverine; Paper; Physostigmine; Sodium Chloride; Strychnine | 1974 |
[Pharmacological studies on analgesics. 8. Significance of calcium in the mechanism of morphine analgesia. (2)].
Topics: Animals; Calcium; Cerebral Cortex; Cocaine; Codeine; Edetic Acid; Male; Morphine; Nalorphine; Ouabain; Pentobarbital; Rats | 1966 |
[Pharmacological studies on analgesics. (IX). Significance of calcium in the mechanism of morphine analgesia. (3)].
Topics: Animals; Calcium; Cerebral Cortex; Cocaine; Edetic Acid; Morphine; Nalorphine; Ouabain; Potassium; Rats; Sodium | 1966 |
Self-administration of psychoactive substances by the monkey.
Topics: Animals; Behavior, Animal; Caffeine; Catheterization; Chlorpromazine; Cocaine; Codeine; Dextroamphetamine; Ethanol; Haplorhini; Humans; Mescaline; Morphinans; Morphine; Morphine Dependence; Pentobarbital; Substance-Related Disorders | 1969 |
Some implications of conditioning theory for problems of drug abuse.
Topics: Amphetamine; Animals; Barbiturates; Cannabis; Cocaine; Conditioning, Classical; Conditioning, Psychological; Culture; Ethanol; Extinction, Psychological; Haplorhini; Humans; Lysergic Acid Diethylamide; Morphine; Psychological Theory; Reinforcement, Psychology; Research; Substance-Related Disorders | 1971 |
Peristaltic activity of isolated stomach and its modification by drugs.
Topics: Acetylcholine; Animals; Anura; Cocaine; Gastrointestinal Motility; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Morphine; Nicotine; Physostigmine; Rabbits; Stomach; Tubocurarine | 1972 |
Drugs that influence behaviour.
Topics: Analgesics; Antidepressive Agents; Barbiturates; Behavior; Cannabis; Cocaine; Hallucinogens; Humans; Hypnotics and Sedatives; Morphine; Substance-Related Disorders; Tranquilizing Agents | 1972 |
Influence of 6-hydroxydopamine and of -methyl-p-tyrosine on the effects of some centrally acting agents.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Catecholamines; Cats; Chlorpromazine; Cocaine; Dopamine; Drug Antagonism; Female; Housing, Animal; Injections; Male; Methylphenidate; Methyltyrosines; Mice; Morphine; Motor Activity | 1972 |
Narcotic drugs: effects on the serotonin biosynthetic systems of the brain.
Topics: Animals; Brain; Carbon Isotopes; Cocaine; Male; Mesencephalon; Mixed Function Oxygenases; Morphine; Nerve Endings; Rats; Serotonin; Synaptic Vesicles; Synaptosomes; Time Factors; Tryptophan | 1972 |
Eosinophilia and drug abuse.
Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Codeine; Eosinophilia; Heroin; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Methadone; Morphine; Substance-Related Disorders | 1972 |
Differential antagonism between DMAE (a hemicholinium derivative) and atropine on contractile responses of the rat ileum.
Topics: Acetylcholine; Animals; Atropine; Biphenyl Compounds; Cocaine; Depression, Chemical; Drug Antagonism; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Nicotine; Quaternary Ammonium Compounds; Rats; Strychnine | 1971 |
Studies on analgesics. VII. Difference between cocaine and amphetamine concerning augmentation of morphine analgesia in mice.
Topics: Amphetamine; Analgesics; Animals; Cocaine; Dihydroxyphenylalanine; Drug Synergism; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Reserpine; Tetrabenazine | 1971 |
Development of morphine dependence in rats: lack of effect of previous ingestion of other drugs.
Topics: Amobarbital; Amphetamine; Animals; Chlordiazepoxide; Cocaine; Drinking Behavior; Drug Antagonism; Ethanol; Humans; Male; Morphine; Morphine Dependence; Rats; Substance-Related Disorders | 1971 |
The action of arecoline on the superior cervical ganglion of the cat.
Topics: Animals; Atropine; Cats; Cocaine; Dimethylphenylpiperazinium Iodide; Drug Antagonism; Female; Ganglia, Autonomic; Ganglionic Stimulants; Male; Methadone; Morphine; Nicotine; Nicotinic Acids; Nictitating Membrane; Parasympathomimetics; Piperazines; Receptors, Drug; Stimulation, Chemical; Sympathetic Nervous System | 1971 |
[Pharmacological responses of the pyloric antrum strip of the rat stomach, with special reference to the mechanism of the contractions caused by serotonin and nicotine, relaxation of transmural stimulation and contraction and relaxation by tyramine].
Topics: Acetylcholine; Animals; Atropine; Barium; Bretylium Compounds; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Haloperidol; In Vitro Techniques; Methysergide; Morphine; Muscle Contraction; Nicotine; Phenoxybenzamine; Physostigmine; Procaine; Propranolol; Pylorus; Rats; Receptors, Drug; Scopolamine; Serotonin; Stimulation, Chemical; Tyramine | 1971 |
Modification of the effect of carotid artery occlusion by various agents.
Topics: Animals; Blood Pressure; Carotid Arteries; Catecholamines; Chloralose; Cocaine; Dogs; Guanethidine; Heart Ventricles; In Vitro Techniques; Morphine; Octopamine; Pargyline; Reserpine; Sympatholytics; Tachyphylaxis; Tyramine | 1967 |
[A simple method of infrared spectrography of microgram quantities].
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Humans; Infrared Rays; Liver; Methods; Morphine; Quinine; Spectrum Analysis; Strychnine | 1969 |
A case history of drug addiction and a T.L.C. system for the separation and identification of some drugs of addiction in sub-microgramme amounts.
Topics: Acute Kidney Injury; Adult; Ammonia; Antitussive Agents; Chloroform; Chromatography, Thin Layer; Cocaine; Cyclizine; Heroin; Humans; Hypotension; Ketones; Male; Methods; Morphine; Pharmaceutical Preparations; Substance-Related Disorders | 1969 |
Drugs: hard and soft distinguished.
Topics: Amphetamine; Cannabis; Cocaine; Codeine; Drug and Narcotic Control; Heroin; Humans; Lysergic Acid Diethylamide; Morphine; Substance-Related Disorders; United Kingdom | 1970 |
[Current drug addiction: clinical effects of agents in use and common semiologic aspects].
Topics: Adolescent; Adult; Age Factors; Amphetamine; Cannabis; Cocaine; Hallucinogens; Heroin; Humans; Hypnotics and Sedatives; Middle Aged; Morphine; Opium; Substance-Related Disorders | 1970 |
Marijuana and the use of other drugs.
Topics: Adult; Alcohol Drinking; Cannabis; Cocaine; Female; Heroin; Humans; Lysergic Acid Diethylamide; Male; Methamphetamine; Morphine; Opium; Rehabilitation Centers; Smoking; Students; Substance-Related Disorders; Surveys and Questionnaires; United States | 1970 |
Drug dependence: pharmacological and physiological aspects.
Topics: Amphetamine; Animals; Barbiturates; Brain; Cannabis; Central Nervous System; Cocaine; Drug Tolerance; Guinea Pigs; Heroin; Humans; Hypothalamus; Ileum; Lysergic Acid Diethylamide; Morphine; Morphine Dependence; Nerve Endings; Opium; Psychoses, Substance-Induced; Substance Withdrawal Syndrome; Substance-Related Disorders | 1970 |
[Gastric acid secretion by vagal stimulation and acid-secreting substances in rats].
Topics: Animals; Atropine; Cocaine; Electric Stimulation; Female; Gastric Juice; Gastrointestinal Hormones; Hexamethonium Compounds; Histamine; Morphine; Parasympathomimetics; Rats; Rats, Inbred Strains; Vagus Nerve | 1970 |
Neuropharmacological properties of Su17595A a chlorpromazine-like central nervous system depressant.
Topics: Animals; Blood Pressure; Brain Stem; Caffeine; Cats; Chlordiazepoxide; Chlorpromazine; Cocaine; Depression, Chemical; Dextroamphetamine; Drug Antagonism; Hypnotics and Sedatives; Male; Mice; Morphine; Morpholines; Motor Activity; Pentylenetetrazole; Piperazines; Propiophenones; Rats; Reflex; Respiration; Seizures; Strychnine; Tranquilizing Agents | 1971 |
Modification of the effect of some central stimulants in mice pretreated with alpha-methyl-1-tyrosine.
Topics: Animals; Body Temperature; Brain; Central Nervous System; Cocaine; Desipramine; Dextroamphetamine; Exophthalmos; Female; Fever; Lysergic Acid Diethylamide; Male; Mescaline; Methyltyrosines; Mice; Morphine; Motor Activity; Norepinephrine; Stimulation, Chemical | 1967 |
Sites of action of some partial agonists on the isolated guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Choline; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Ethanol; Guinea Pigs; Hexamethonium Compounds; Ileum; Male; Morphine; Muscle Contraction; Nicotine; Pilocarpine; Stimulation, Chemical; Strychnine | 1968 |
The effects of submucous resection and rhinoplasty on the sense of smell.
Topics: Cocaine; Edema; Female; Humans; Male; Morphine; Nasal Mucosa; Nose; Odorants; Olfaction Disorders; Olfactory Nerve; Pentobarbital; Postoperative Complications; Preanesthetic Medication; Rhinoplasty; Smell | 1968 |
Separation and identification of alkaloids by paper electrophoresis and its application in medico-legal cases.
Topics: Aconitum; Alkaloids; Atropa belladonna; Cocaine; Codeine; Color; Electrophoresis; Ephedrine; Fluorescence; Forensic Medicine; Methods; Morphine; Nicotine; Noscapine; Papaverine; Parasympathomimetics; Physostigmine; Plants, Medicinal; Plants, Toxic; Procaine; Quinine; Solanine; Strychnine; Thebaine; Ultraviolet Rays | 1968 |
Drug addiction--the extent and nature of the problem.
Topics: Alcoholism; Amphetamine; Barbiturates; Cannabis; Cocaine; England; Hallucinogens; Heroin; Humans; Morphine; Opium; Social Problems; Substance-Related Disorders; World Health Organization | 1968 |
Potentiation of morphine analgesia by cocaine in mice.
Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine | 1968 |
Effect of nerve function inhibitors on pentagastrin stimulated acid secretion by isolated bullfrog gastric mucosa.
Topics: Acetylcholine; Animals; Anura; Atropine; Cocaine; Gastric Juice; Gastric Mucosa; Gastrins; Morphine; Nervous System Physiological Phenomena; Peptides; Succinylcholine; Tetrodotoxin; Tubocurarine | 1968 |
[Current problems posed by the abuse of psychotropic drugs].
Topics: Amphetamine; Barbiturates; Cannabis; Cocaine; Hallucinogens; Humans; Morphine; Substance-Related Disorders | 1968 |
D-receptor for serotonin on blood platelets.
Topics: Adenine Nucleotides; Animals; Atropine; Blood Coagulation; Blood Platelets; Cocaine; Drug Synergism; Guinea Pigs; Ileum; Lysergic Acid Diethylamide; Morphine; Muscle, Smooth; Phenoxybenzamine; Receptors, Drug; Serotonin; Serotonin Antagonists; Sheep; Thrombosis | 1969 |
Gas chromatographic determination of morphine and cocaine in urine.
Topics: Chromatography, Gas; Cocaine; Humans; Morphine | 1969 |
Effect of atropine and DMAE (a hemicholinium derivative) on contractile responses of the guinea pig ileum.
Topics: Acetylcholine; Animals; Atropine; Cocaine; Electric Stimulation; Female; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Parasympatholytics; Quaternary Ammonium Compounds | 1969 |
Thin-layer chromatographic detection of barbiturates, narcotics, and amphetamines in urine of patients receiving psychotropic drugs.
Topics: Amphetamine; Barbiturates; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Imipramine; Ion Exchange Resins; Meperidine; Methadone; Morphine; Narcotics; Quinine; Thioridazine; Trifluoperazine | 1969 |
The effects of drugs on uptake and exit of cerebral amino acids.
Topics: Adenosine Triphosphate; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Brain; Chlorpromazine; Cocaine; Hypothermia, Induced; Lysergic Acid Diethylamide; Lysine; Mescaline; Mice; Morphine; Ouabain; Pentobarbital; Phenobarbital; Reserpine | 1965 |
Effects of cocaine administration on brain, adrenal and urinary adrenaline and noradrenaline in rats.
Topics: Adrenal Medulla; Animals; Brain; Cocaine; Epinephrine; In Vitro Techniques; Morphine; Norepinephrine; Rats; Urine | 1964 |
Gas chromatography of alkaloids with polar stationary liquids.
Topics: Alkaloids; Atropine; Chromatography, Gas; Cinchona; Cocaine; Codeine; Morphine; Papaverine; Pilocarpine; Plants, Medicinal; Quinidine; Quinine; Scopolamine; Strychnine; Thebaine | 1965 |
Interaction of catecholamines with levorphanol and morphine in the mouse eye.
Topics: Amphetamine; Animals; Catecholamines; Cocaine; Drug Tolerance; Endotoxins; Ethanol; Eye Diseases; Histamine; In Vitro Techniques; Lens, Crystalline; Levorphanol; Metaraminol; Methacholine Compounds; Mice; Morphine; Phenoxybenzamine; Phenylephrine; Reserpine; Serotonin; Sympatholytics | 1966 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm | 1966 |
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cocaine; Cold Temperature; Colon; Guinea Pigs; Hexamethonium Compounds; Histamine; Hypoxia; In Vitro Techniques; Mecamylamine; Morphine; Muscle Contraction; Nicotine; Pentolinium Tartrate; Procaine; Scopolamine; Serotonin; Tetraethylammonium Compounds; Vasopressins | 1966 |
[Characterization of the mechanism of action of an intestine contracting polypeptide from the brain by means of antagonists].
Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Cocaine; Guinea Pigs; Ileum; In Vitro Techniques; Intestines; Morphine; Muscle Contraction; Muscle, Smooth; Peptides; Physostigmine; Stimulation, Chemical | 1966 |
Four cases of progressive drug abuse.
Topics: Adult; Alcohols; Amphetamine; Barbiturates; Cannabis; Cocaine; Humans; Lysergic Acid Diethylamide; Male; Methylphenidate; Morphine; Opium; Substance-Related Disorders | 1967 |
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus | 1967 |
Reduction of conditioned suppression: actions of morphine compared with those of amphetamine, pentobarbital, nalorphine, cocaine, LSD-25 and chlorpromazine.
Topics: Amphetamine; Animals; Behavior, Animal; Chlorpromazine; Cocaine; Conditioning, Psychological; Lysergic Acid Diethylamide; Morphine; Nalorphine; Pentobarbital; Rats | 1967 |
Progress report from the NIDA Addiction Research Center (preclinical laboratory), Lexington, Kentucky (1984).
Topics: Aging; Animals; Behavior, Animal; beta-Endorphin; Cats; Cocaine; Discrimination Learning; Dogs; Endorphins; Humans; Loperamide; Morphine; National Institutes of Health (U.S.); Norbornanes; Pupil; Rats; Reinforcement, Psychology; Substance-Related Disorders; United States | 1984 |
Saturable (3H)cocaine binding in central nervous system of mouse.
Topics: Animals; Brain; Cell Membrane; Cocaine; Male; Mice; Morphine; Naloxone; Neurotransmitter Agents; Nicotine; Tubocurarine | 1980 |
Treatment of moderate & severe chronic pain syndromes with morphine & adjunctive drugs.
Topics: Amphetamine; Chronic Disease; Cocaine; Doxapram; Histamine H1 Antagonists; Humans; Morphine; Narcotics; Pain; Phenothiazines; Syndrome | 1981 |
Contrasting interactions of pipradrol, d-amphetamine, cocaine, cocaine analogues, apomorphine and other drugs with conditioned reinforcement.
Topics: Animals; Apomorphine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Flupenthixol; Male; Morphine; Piperidines; Rats; Reinforcement, Psychology | 1983 |
A new series of oral medications for chronic (cancer) pain relief.
Topics: Administration, Oral; Aluminum Hydroxide; Analgesics, Opioid; Antacids; Antiemetics; Cimetidine; Cocaine; Drug Administration Schedule; Drug Combinations; Humans; Hydroxyzine; Long-Term Care; Morphine; Nausea; Neoplasms; Pain; Vomiting | 1984 |
Strong analgesics in severe pain.
Topics: Analgesics, Opioid; Chronic Disease; Cocaine; Fentanyl; Half-Life; Heroin; Humans; Injections, Intramuscular; Methadone; Morphine; Pain, Intractable; Pain, Postoperative | 1984 |
Spin immunoassay.
Topics: Blood Proteins; Cocaine; Dronabinol; Electron Spin Resonance Spectroscopy; Humans; Immunoassay; Morphine; Narcotics; Pharmaceutical Preparations; Phenytoin; Progesterone; Saliva; Spin Labels | 1981 |
Drug reinforcement studied by the use of place conditioning in rat.
Topics: Animals; Chlorides; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Functional Laterality; Lithium; Lithium Chloride; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement, Psychology | 1982 |
Discriminative stimulus properties of d-amphetamine in pigeons.
Topics: Amphetamine; Animals; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dronabinol; Lysergic Acid Diethylamide; Male; Morphine; Propranolol | 1982 |
Notes on Dr. William S. Halsted.
Topics: Cocaine; General Surgery; History, 19th Century; History, 20th Century; Humans; Male; Morphine; Morphine Dependence; Substance-Related Disorders; United States | 1984 |
Reinstatement of heroin and cocaine self-administration behavior in the rat by intracerebral application of morphine in the ventral tegmental area.
Topics: Animals; Caudate Nucleus; Cocaine; Extinction, Psychological; Heroin; Injections; Morphine; Rats; Rats, Inbred Strains; Self Administration; Tegmentum Mesencephali; Time Factors | 1984 |
Effects of helium-oxygen and hyperbaric helium-oxygen environment on drug-metabolizing enzyme activity in rat liver.
Topics: Animals; Atmosphere Exposure Chambers; Body Weight; Cocaine; Helium; Liver; Male; Morphine; Nitroanisole O-Demethylase; Organ Size; Oxygen; Pressure; Rats; Time Factors | 1983 |
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri | 1983 |
[Effect of methamphetamine on morphine preference].
Topics: Animals; Caffeine; Choice Behavior; Cocaine; Drug Combinations; Humans; Male; Methamphetamine; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Taste | 1983 |
Strategies for studying the neurochemical substrates of drug reinforcement in rodents.
Topics: Amphetamine; Animals; Brain; Cocaine; Conditioning, Operant; Dopamine; Hypothalamus; Limbic System; Morphine; Nucleus Accumbens; Psychotropic Drugs; Rats; Receptors, Dopamine; Reinforcement, Psychology; Self Administration; Self Stimulation; Substantia Nigra | 1983 |
Conditioned and unconditioned drug effects in relapse to opiate and stimulant drug self-adminstration.
Topics: Animals; Brain; Cocaine; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Heroin; Injections, Intravenous; Morphine; Rats; Self Administration; Tegmentum Mesencephali | 1983 |
Qualitative measurement of drugs.
Topics: Adult; Anesthetics; Cocaine; Dextroamphetamine; Double-Blind Method; Electronystagmography; Evoked Potentials; Humans; Infant, Newborn; Meperidine; Middle Aged; Morphine; Nystagmus, Physiologic; Phenobarbital; Secobarbital | 1984 |
Body temperature response to cocaine and diazepam in morphine-treated rats.
Topics: Animals; Body Temperature; Cocaine; Diazepam; Drug Interactions; Humans; Male; Morphine; Morphine Dependence; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Temperature; Time Factors | 1982 |
Systems of reinforcement and drug dependence.
Topics: Amphetamines; Animals; Cats; Chlordiazepoxide; Cocaine; Diazepam; Drug Tolerance; Escape Reaction; Ethanol; Heroin; Humans; Morphine; Pentobarbital; Psychophysiology; Rats; Reinforcement, Psychology; Substance Withdrawal Syndrome; Substance-Related Disorders | 1982 |
[Determination of the development of psychotic dependence to drugs in small animals. 2. Selective drinking of morphine and cocaine solutions and its reinforcement in mice].
Topics: Animals; Choice Behavior; Circadian Rhythm; Cocaine; Drinking; Humans; Injections, Intraperitoneal; Male; Mice; Morphine; Solutions; Substance-Related Disorders | 1981 |
[Possibilities of discontinuing therapeutic use of cocaine and its salts].
Topics: Adult; Aged; Attitude of Health Personnel; Child; Cocaine; France; Humans; Morphine; Neoplasms; Pain; Physicians | 1980 |
[Comparison of the effects of several psychotropic drugs by gross behavioral observation on rhesus monkeys].
Topics: Amphetamines; Animals; Barbital; Behavior, Animal; Chlorpromazine; Cocaine; Diazepam; Female; Imipramine; Lysergic Acid Diethylamide; Macaca mulatta; Male; Morphine; Psychotropic Drugs | 1981 |
[Action on the emotional-reinforcement systems of the brain as a means of pathogenetic therapy for alcoholism and drug addiction].
Topics: Amphetamine; Animals; Carbolines; Cocaine; Dioxanes; Drug Evaluation, Preclinical; Ethanol; Humans; Lithium; Morphine; Naloxone; Pentobarbital; Pyrrolidines; Rats; Self Stimulation; Substance-Related Disorders | 1980 |
Locomotor activity in morphine-treated rats: effects of and comparisons between cocaine, procaine, and lidocaine.
Topics: Animals; Cocaine; Humans; Lidocaine; Male; Morphine; Morphine Dependence; Motor Activity; Procaine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1981 |
Stability of Brompton mixtures: determination of heroin (diacetylmorphine) and cocaine in presence of their hydrolysis products.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cocaine; Drug Stability; Ethanol; Heroin; Hydrolysis; Morphine | 1980 |
A simple solid-phase radioimmunoassay for morphine and related opiates using a mixture of labelled morphine and antiserum pre-precipitated by polyethylene glycol.
Topics: Barbiturates; Chemical Precipitation; Cocaine; Cross Reactions; Diazepam; Humans; Immune Sera; Methaqualone; Morphine; Narcotics; Phencyclidine; Polyethylene Glycols; Radioimmunoassay | 1981 |
Hair as the sample in assessing morphine and cocaine addiction.
Topics: Cocaine; Hair; Humans; Morphine; Morphine Dependence; Radioimmunoassay; Substance-Related Disorders | 1981 |
Effects of cocaine and morphine on concurrent schedule-controlled performances.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Morphine; Reaction Time; Time Factors | 1980 |
Inhibition of Ca2+-induced noradrenaline release from central noradrenergic neurons by morphine.
Topics: Animals; Calcium; Cerebral Cortex; Cocaine; Male; Morphine; Naloxone; Neurons; Norepinephrine; Phentolamine; Rats | 1980 |
The effect of (D-Ala2)-Met-enkephalin on the contraction of nictitating membrane in cats.
Topics: Animals; Cats; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Male; Morphine; Muscle Contraction; Naloxone; Nictitating Membrane; Norepinephrine; Sympathetic Nervous System | 1980 |
[The 'Brompton Cocktail'].
Topics: Administration, Oral; Cocaine; Humans; Morphine | 1980 |
Cocaine self-administration and naltrindole, a delta-selective opioid antagonist.
Topics: Animals; Cocaine; Conditioning, Operant; Drug Implants; Female; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Opioid, delta; Self Administration | 1995 |
Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1995 |
Activation of xenobiotics into free radicals by prostaglandin-H-synthase and by rat liver microsomes.
Topics: Animals; Cocaine; Free Radicals; Histamine Release; Malondialdehyde; Mast Cells; Methadone; Microsomes, Liver; Morphine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Xenobiotics | 1995 |
Kappa opioid inhibition of morphine and cocaine self-administration in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cocaine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Morphine; Naltrexone; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration | 1995 |
Ethanol, morphine and barbiturate alter the hemodynamic and cerebral response to cocaine in newborn pigs.
Topics: Animals; Animals, Newborn; Barbiturates; Blood Pressure; Brain; Cerebrovascular Circulation; Cocaine; Drug Interactions; Ethanol; Morphine; Oxygen; Swine | 1995 |
OnLine kinetic microparticle immunoassay of cannabinoids, morphine, and benzoylecgonine in serum.
Topics: Cannabinoids; Cocaine; Immunoassay; Indicators and Reagents; Kinetics; Microspheres; Morphine; Substance Abuse Detection | 1995 |
Interaction between discriminative stimulus effects of cocaine and morphine.
Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred F344; Synaptic Transmission | 1995 |
Chronic treatment with morphine and ethanol, but not cocaine, attenuates IL-1 beta activation of FOS expression in the rat hypothalamic paraventricular nucleus.
Topics: Animals; Cocaine; Ethanol; Gene Expression; Genes, fos; Immunohistochemistry; Interleukin-1; Male; Morphine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 1995 |
Sertindole antagonizes morphine-, cocaine-, and methamphetamine-induced place preference in the rat.
Topics: Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Fluphenazine; Haloperidol; Imidazoles; Indoles; Male; Methamphetamine; Morphine; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior | 1995 |
The effect of chronic morphine and cocaine administration on the Gs and Go protein messenger RNA levels in the rat hippocampus.
Topics: Animals; Cocaine; GTP-Binding Proteins; Hippocampus; Immunohistochemistry; In Situ Hybridization; Male; Morphine; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Sulfur Radioisotopes | 1994 |
Adverse effects of paternal opiate exposure on offspring development and sensitivity to morphine-induced analgesia.
Topics: Analgesia; Animals; Cocaine; Female; Fertility; Fetus; Male; Morphine; Paternal Exposure; Rats; Stress, Physiological | 1995 |
Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics.
Topics: Amphetamine; Animals; Benzazepines; Cocaine; Conditioning, Classical; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Male; Morphine; Raclopride; Rats; Rats, Sprague-Dawley; Reward; Salicylamides; Time Factors | 1995 |
Conditioned place preference induced by delta 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Classical; Dronabinol; Food; Male; Morphine; Rats; Reward | 1995 |
Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Male; Morphine; Motor Activity; Nerve Endings; Nucleus Accumbens; Rats; Rats, Wistar; Ventral Tegmental Area | 1995 |
Detection of drugs-of-abuse in meconium of a stillborn baby and in stool of a deceased 41-day-old infant.
Topics: Adult; Cocaine; Feces; Female; Fetal Death; Humans; Hydrocephalus; Infant; Infant, Newborn; Male; Meconium; Morphine; Pregnancy; Substance-Related Disorders | 1995 |
Simultaneous determination of opiates, cocaine and major metabolites of cocaine in human hair by gas chromotography/mass spectrometry (GC/MS).
Topics: Adolescent; Adult; Calibration; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Ethylmorphine; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Male; Morphine; Morphine Derivatives; Narcotics; Reproducibility of Results | 1995 |
Drug discrimination analysis of midazolam under a three-lever procedure: I. Dose-dependent differences in generalization and antagonism.
Topics: Animals; Caffeine; Cocaine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Methocarbamol; Midazolam; Morphine; Pentobarbital; Rats; Rats, Sprague-Dawley | 1995 |
Drugs of abuse screening in the West Midlands: a 6 year retrospective survey of results.
Topics: Amphetamine; Cannabinoids; Chromatography, Thin Layer; Cocaine; Codeine; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Phenobarbital; Retrospective Studies; Substance-Related Disorders; United Kingdom | 1994 |
Hair and urine analysis: relative distribution of drugs and their metabolites.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Morphine; Morphine Derivatives; Narcotics; Substance-Related Disorders | 1995 |
Differential modification of the rewarding effects of methamphetamine and cocaine by opioids and antihistamines.
Topics: Animals; Appetite; Chlorpheniramine; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Histamine Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward | 1993 |
Alterations in striatal acetylcholine overflow by cocaine, morphine, and MK-801: relationship to locomotor output.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Space; Male; Microdialysis; Morphine; Motor Activity; Neostriatum; Rats; Rats, Sprague-Dawley | 1994 |
[Two traffic accidents after heroin consumption with fatal outcome].
Topics: Accidents, Traffic; Cause of Death; Cocaine; Codeine; Fatal Outcome; Heroin; Heroin Dependence; Humans; Morphine; Substance-Related Disorders | 1994 |
Prenatal cocaine potentiates the effects of morphine in adult mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Drug Synergism; Female; Mice; Morphine; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction | 1994 |
[Diversified prescription of narcotics to heroin addicts. Basis, design, research plan].
Topics: Clinical Trials as Topic; Cocaine; Drug Prescriptions; Female; Heroin; Humans; Male; Methadone; Morphine; Narcotics; Opioid-Related Disorders; Pilot Projects; Program Evaluation; Research Design | 1994 |
The CCKA receptor antagonist devazepide does not modify opioid self-administration or drug discrimination: comparison with the dopamine antagonist haloperidol.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Conditioning, Operant; Cues; Devazepide; Discrimination, Psychological; Dopamine Antagonists; Food; Haloperidol; Heroin; Male; Morphine; Narcotics; Phenylurea Compounds; Rats; Rats, Wistar; Receptors, Cholecystokinin; Self Administration | 1994 |
[Alteration of cocaine, morphine and nicotine levels in serum of opiomaniacs treated by jie du ling].
Topics: Adolescent; Adult; Cocaine; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Morphine; Nicotine; Opioid-Related Disorders; Radioimmunoassay | 1994 |
[Trends in drugs-of-abuse in Los Angeles County].
Topics: Amphetamines; Cocaine; Female; Heroin; Humans; Infant, Newborn; Los Angeles; Male; Morphine; Phencyclidine; Pregnancy; Pregnancy Complications; Substance-Related Disorders | 1994 |
An investigation into the discriminative stimulus and reinforcing properties of the CCKB-receptor antagonist, L-365,260 in rats.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Cocaine; Diazepam; Discrimination, Psychological; Drug Synergism; Gastric Acid; Male; Morphine; Naloxone; Pentagastrin; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Self Administration; Sodium Chloride | 1994 |
Coordinate and independent effects of cocaine, alcohol, and morphine on accumulation of IgG aggregates in the rat glomeruli.
Topics: Alcoholism; Animals; Cocaine; Drug Interactions; Ethanol; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Gold; Humans; Immunoglobulin G; Iodine Radioisotopes; Kidney Glomerulus; Liver; Lung; Male; Morphine; Rats; Rats, Sprague-Dawley; Spleen; Substance-Related Disorders | 1994 |
Drug distribution in the head, axillary and pubic hair of chronic addicts.
Topics: Adult; Axilla; Benzodiazepines; Body Fluids; Chronic Disease; Cocaine; Drug Overdose; Genitalia; Hair; Head; Humans; Illicit Drugs; Male; Morphine; Radioimmunoassay; Substance Abuse Detection; Substance-Related Disorders; Tissue Distribution | 1993 |
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.
Topics: Adult; Amphetamine; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders | 1993 |
Ion trap mass spectrometry, a new tool in the investigation of drugs of abuse in hair.
Topics: Cocaine; Hair; Humans; Illicit Drugs; Mass Spectrometry; Morphine; Substance Abuse Detection | 1993 |
Interlaboratory comparison studies on the analysis of hair for drugs of abuse.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Morphine; Predictive Value of Tests; Radioimmunoassay; Reproducibility of Results; Substance Abuse Detection | 1993 |
Corticosterone circadian secretion differentially facilitates dopamine-mediated psychomotor effect of cocaine and morphine.
Topics: Adrenalectomy; Analysis of Variance; Animals; Brain; Circadian Rhythm; Cocaine; Corticosterone; Dopamine; Drug Implants; Limbic System; Male; Morphine; Motor Activity; Neurons; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 1994 |
Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization.
Topics: Amphetamine; Analysis of Variance; Animals; Cocaine; Dizocilpine Maleate; Drug Interactions; Male; Morphine; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1993 |
Suppression of opiate withdrawal and cocaine hyperarousal syndromes by buspirone. Possible pharmacotherapeutic applications.
Topics: Animals; Arousal; Buspirone; Cocaine; Female; Macaca mulatta; Male; Morphine; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome | 1993 |
Capillary electrophoresis for the investigation of illicit drugs in hair: determination of cocaine and morphine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Electrophoresis; Hair; Humans; Illicit Drugs; Morphine; Spectrophotometry, Ultraviolet; Substance Abuse Detection | 1993 |
Prenatal exposure to morphine enhances cocaine and heroin self-administration in drug-naive rats.
Topics: Animals; Brain; Cocaine; Female; Heroin Dependence; Male; Morphine; Morphine Dependence; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Opioid; Self Administration; Substance-Related Disorders | 1993 |
Effect of cocaine and morphine on neutral endopeptidase activity of human peripheral blood mononuclear cells cultured with lectins.
Topics: Antigens, CD; Biomarkers; Cell Division; Cells, Cultured; Cocaine; Humans; Lectins; Leukocytes, Mononuclear; Lymphocyte Activation; Morphine; Neprilysin; Subcellular Fractions; Tumor Cells, Cultured | 1993 |
Macrophage functions in drugs of abuse-treated mice.
Topics: Animals; Cell Division; Cells, Cultured; Cocaine; Interleukin-1; Leukemia L1210; Macrophages, Peritoneal; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Adaptation of the meconium drug test for mass screening.
Topics: Cannabinoids; Cocaine; Female; Humans; Infant, Newborn; Meconium; Morphine; Narcotics; Neonatal Abstinence Syndrome; Neonatal Screening; Pregnancy; Pregnancy Complications; Substance-Related Disorders | 1993 |
Effects of the central analgesic tramadol on the uptake and release of noradrenaline and dopamine in vitro.
Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chinchilla; Cocaine; Dopamine; Female; In Vitro Techniques; Male; Morphine; Naloxone; Norepinephrine; Rabbits; Rats; Rats, Sprague-Dawley; Stereoisomerism; Synaptosomes; Tramadol; Yohimbine | 1993 |
Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system.
Topics: Actins; Adenylyl Cyclases; Animals; Autoradiography; Cocaine; Cyclic AMP-Dependent Protein Kinases; Dopamine; Glial Fibrillary Acidic Protein; Injections; Limbic System; Male; Morphine; Narcotic Antagonists; Narcotics; Nerve Growth Factors; Neurofilament Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 1995 |
Supercritical fluid extraction of drugs in drug addict hair.
Topics: Cannabinoids; Carbon Dioxide; Cocaine; Codeine; Ethylamines; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methanol; Morphine; Morphine Derivatives; Narcotics; Opioid-Related Disorders; Reproducibility of Results; Solutions; Temperature; Water | 1995 |
Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents.
Topics: Animals; Antibody Specificity; Blotting, Western; Cocaine; Dopamine; Drug Tolerance; Male; Morphine; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Stress, Physiological; Ventral Tegmental Area | 1996 |
Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Extracellular Space; Injections, Intravenous; Kinetics; Male; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Stereotyped Behavior; Time Factors | 1995 |
Forensic immunochemistry.
Topics: Central Nervous System Agents; Cocaine; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Humans; Latex Fixation Tests; Methamphetamine; Morphine; Phenobarbital; Radioimmunoassay; Sensitivity and Specificity; Substance-Related Disorders | 1996 |
Free radical mediated release of histamine from rat mast cells induced by drugs of abuse.
Topics: Animals; Cocaine; Cyclic N-Oxides; Dose-Response Relationship, Drug; Fluorometry; Free Radical Scavengers; Free Radicals; Glutathione; Histamine Release; Illicit Drugs; L-Lactate Dehydrogenase; Malondialdehyde; Mast Cells; Methadone; Morphine; Narcotics; Peritoneal Cavity; Pleura; Rats; Rats, Wistar; Spectrophotometry; Vitamin E | 1996 |
Drugs of abuse and immunosuppression.
Topics: Animals; Cannabinoids; Cocaine; Humans; Immune System; Morphine; Narcotics | 1994 |
Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cocaine; Dopamine; Male; Morphine; Nerve Growth Factors; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tegmentum Mesencephali | 1996 |
18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats.
Topics: Animals; Cerebellum; Cocaine; Dopamine; Female; Ibogaine; Limbic System; Morphine; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Self Administration; Tremor | 1996 |
A common mechanism mediates long-term changes in synaptic transmission after chronic cocaine and morphine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cocaine; Colforsin; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; Membrane Potentials; Morphine; Receptors, GABA-B; Synaptic Transmission; Time Factors | 1996 |
Effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons.
Topics: Animals; Cocaine; Dopamine; Ibogaine; Morphine; Neurons; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 1996 |
Adrenalectomy potentiates the morphine--but not cocaine-induced place preference in rats.
Topics: Adrenalectomy; Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley | 1995 |
Tolerance and crosstolerance to the suppressive effects of cocaine and morphine on lymphocyte proliferation.
Topics: Animals; Cell Division; Cocaine; Depression, Chemical; Drug Tolerance; Killer Cells, Natural; Leukocyte Count; Lymphocytes; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1996 |
The cocaine-like behavioral effects of meperidine are mediated by activity at the dopamine transporter.
Topics: Animals; Behavior, Animal; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Meperidine; Models, Molecular; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Saimiri | 1996 |
Effects of calcium channel antagonists on the reinforcing properties of morphine, ethanol and cocaine as measured by place conditioning.
Topics: Animals; Calcium; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Ethanol; Male; Morphine; Nifedipine; Rats; Rats, Wistar; Reward; Substance-Related Disorders | 1996 |
Formalin- and carrageenan-induced inflammation attenuates place preferences produced by morphine, methamphetamine and cocaine.
Topics: Animals; Behavior, Animal; Carrageenan; Cocaine; Conditioning, Operant; Formaldehyde; Indomethacin; Inflammation; Male; Methamphetamine; Morphine; Narcotics; Pain; Rats; Rats, Sprague-Dawley | 1996 |
Comparison of heroin and cocaine concentrations in saliva with concentrations in blood and plasma.
Topics: Administration, Inhalation; Cocaine; Gas Chromatography-Mass Spectrometry; Half-Life; Heroin; Humans; Illicit Drugs; Injections, Intravenous; Male; Morphine; Morphine Derivatives; Narcotics; Saliva | 1995 |
A 5-year stability study of common illicit drugs in blood.
Topics: Amphetamine; Calibration; Cocaine; Codeine; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Narcotics; Phencyclidine | 1995 |
ONTRAK TESTCUP: a novel, on-site, multi-analyte screen for the detection of abused drugs.
Topics: Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Online Systems; Reference Standards; Reproducibility of Results; Substance Abuse Detection | 1995 |
Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: comparisons between acute drug treatment and a drug challenge in sensitized animals.
Topics: Animals; Caudate Nucleus; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Administration Schedule; Genes, fos; Male; Morphine; Neurons; Organ Specificity; Prosencephalon; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatosensory Cortex; Transcription, Genetic | 1996 |
Effects of interdose interval on ambulatory sensitization to methamphetamine, cocaine and morphine in mice.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Drug Administration Schedule; Locomotion; Male; Methamphetamine; Mice; Mice, Inbred Strains; Morphine; Narcotics; Sensitivity and Specificity; Stimulation, Chemical | 1996 |
Sigma ligand S14905 and locomotor activity in mice.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Hydroxamic Acids; Indans; Male; Mice; Morphine; Motor Activity; Narcotics; Piperidines; Radioligand Assay; Receptors, sigma; Stimulation, Chemical | 1995 |
Assessment of an automated immunoassay based on kinetic interaction of microparticles in solution for determination of opiates and cocaine metabolite in urine.
Topics: Autoanalysis; Chromatography; Cocaine; Codeine; Cross Reactions; Humans; Immunoassay; Mass Spectrometry; Morphine; Morphine Derivatives; Narcotics; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity | 1997 |
William Stewart Halsted: transitional years.
Topics: Baltimore; Cocaine; General Surgery; History, 19th Century; History, 20th Century; Hospitals; Humans; Male; Morphine; New York City; Substance-Related Disorders | 1997 |
Kappa-opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred DBA; Morphine; Narcotics; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration | 1997 |
Conditioned taste aversions and drugs of abuse: a reinterpretation.
Topics: Animals; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Illicit Drugs; Injections, Intraperitoneal; Injections, Subcutaneous; Lithium Chloride; Male; Morphine; Motivation; Rats; Rats, Sprague-Dawley; Taste | 1997 |
Differential effects of mu-, delta- and kappa-opioid receptor agonists on the discriminative stimulus properties of cocaine in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analysis of Variance; Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Morphine; Narcotics; Pyrrolidines; Quinolines; Rats; Rats, Inbred F344; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance-Related Disorders | 1997 |
[Histopathological study on acute poisoning of methamphetamine, morphine or cocaine].
Topics: Animals; Behavior, Animal; Cocaine; Kidney; Liver; Lung; Male; Methamphetamine; Morphine; Myocardium; Rats; Rats, Wistar; Time Factors | 1997 |
Serotonergic receptors modify the voluntary intake of alcohol and morphine but not of cocaine and nicotine by rats.
Topics: Alcohol Drinking; Animals; Choice Behavior; Cocaine; Fluvoxamine; Male; Morphine; Narcotics; Nicotine; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1997 |
Intracranial self-stimulation in female and male rats: no sex differences using a rate-independent procedure.
Topics: Animals; Brain Mapping; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Electric Stimulation; Estrus; Female; Humans; Hypothalamic Area, Lateral; Male; Medial Forebrain Bundle; Morphine; Motivation; Neural Pathways; Rats; Rats, Sprague-Dawley; Self Stimulation; Sex Characteristics | 1997 |
Effect of drugs and cocaine metabolites on cocaine and cocaethylene binding to human serum in vitro.
Topics: Amphetamine; Analgesics, Opioid; Blood Proteins; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Methamphetamine; Morphine; Narcotics | 1997 |
Pain-related laser-evoked potentials in awake monkeys: identification of components, behavioral correlates and drug effects.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Chlorocebus aethiops; Cocaine; Evoked Potentials; Lasers; Male; Morphine; Movement; Naloxone; Narcotic Antagonists; Narcotics; Neural Conduction; Pain; Pain Measurement; Tail; Time Factors | 1997 |
D1-receptor regulation of synaptic potentials in the ventral tegmental area after chronic drug treatment.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Dopamine; Dopamine Agonists; Guinea Pigs; In Vitro Techniques; Morphine; Morphine Dependence; Purinergic P1 Receptor Antagonists; Receptors, Dopamine D1; Receptors, GABA-B; Receptors, Purinergic P1; Substance-Related Disorders; Synaptic Transmission; Tegmentum Mesencephali | 1998 |
Ethanol, like psychostimulants and morphine, causes long-lasting hyperreactivity of dopamine and acetylcholine neurons of rat nucleus accumbens: possible role in behavioural sensitization.
Topics: Acetylcholine; Amphetamine; Animals; Central Nervous System Depressants; Cocaine; Dopamine; Ethanol; Male; Morphine; Motor Activity; Narcotics; Neostriatum; Neurons; Nucleus Accumbens; Rats; Rats, Wistar | 1997 |
Regulation of glutathione and cell toxicity following exposure to neurotropic substances and human immunodeficiency virus-1 in vitro.
Topics: AIDS Dementia Complex; Carrier Proteins; Cell Survival; Cells, Cultured; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Glutathione; HIV-1; Humans; Macrophages; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Narcotics; Nerve Tissue Proteins; Oxidative Stress; Selegiline; Substance-Related Disorders; Tumor Cells, Cultured; Up-Regulation | 1997 |
Modulatory effects of morphine, U-50488H and 1,3-di-(2-tolyl)guanidine on cocaine-like discriminative stimulus in the rat using two-choice discrete-trial avoidance paradigm.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Animals; Avoidance Learning; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Guanidines; Male; Morphine; Rats; Receptors, Opioid | 1997 |
A comparison of ONTRAK TESTCUP, abuscreen ONTRAK, abuscreen ONLINE, and GC/MS urinalysis test results.
Topics: Cannabinoids; Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Morphine; Narcotics; Quality Control; Sensitivity and Specificity; Substance Abuse Detection; Toxicology; Urinalysis | 1998 |
Urine drug testing for social service agencies in Nova Scotia, Canada.
Topics: Benzodiazepines; Cannabinoids; Cocaine; Codeine; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Nova Scotia; Prevalence; Social Work; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1998 |
Effects of prenatal morphine and cocaine exposure on spinal sexual reflexes in male and female rats.
Topics: Animals; Cocaine; Female; Male; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reflex; Sexual Behavior, Animal | 1998 |
Effects of cocaine and morphine in rats from two psychogenetically selected lines: a behavioral and brain dialysis study.
Topics: Analysis of Variance; Animals; Avoidance Learning; Brain Chemistry; Cocaine; Dialysis; Dopamine; Dopamine Uptake Inhibitors; Male; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1997 |
Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Morphine; Narcotic Antagonists; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Interactions of cocaine with morphine, U-50,488H and [D-Pen2, D-Pen5]enkaphalin.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cocaine; Drug Interactions; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hot Temperature; Male; Mice; Morphine; Pain; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1998 |
Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Morpholines; Motor Activity; Naphthalenes; Narcotics; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1998 |
Setting cutoff concentrations for immunoassay screening of postmortem blood.
Topics: Amphetamines; Barbiturates; Cocaine; False Positive Reactions; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Morphine; Radioimmunoassay; ROC Curve; Sensitivity and Specificity; Substance Abuse Detection | 1998 |
Attempts to classify dependence-liable drugs by using a simple drug-discrimination test in mice.
Topics: Analgesics, Opioid; Animals; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Male; Methamphetamine; Mice; Morphine | 1998 |
Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals.
Topics: Animals; Biotransformation; Cell Separation; Cocaine; Dopamine Uptake Inhibitors; Enzyme Induction; Free Radical Scavengers; Free Radicals; Histamine Release; Illicit Drugs; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Mast Cells; Methadone; Microsomes, Liver; Morphine; Narcotics; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar | 1998 |
Sensitization to the conditioned rewarding effects of morphine and cocaine: differential effects of the kappa-opioid receptor agonist U69593.
Topics: Analgesics; Animals; Benzeneacetamides; Cocaine; Conditioning, Operant; Cues; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward | 1998 |
Hair analysis for abused drugs by capillary zone electrophoresis with field-amplified sample stacking.
Topics: Cocaine; Electrophoresis, Capillary; Follow-Up Studies; Hair; Hallucinogens; Humans; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Reproducibility of Results; Sensitivity and Specificity; Substance-Related Disorders | 1998 |
Sensitization to the rewarding effects of the specific dopamine uptake inhibitor GBR12783.
Topics: Animals; Anxiety; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Image Processing, Computer-Assisted; Male; Morphine; Narcotics; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Stereotyped Behavior | 1998 |
Effects of amphetamine, butorphanol, and morphine pretreatment on the maintenance and reinstatement of cocaine-reinforced responding.
Topics: Amphetamine; Animals; Butorphanol; Cocaine; Conditioning, Operant; Drug Interactions; Male; Morphine; Narcotics; Rats; Rats, Wistar; Self Administration | 1998 |
Determination of five abused drugs in nitrite-adulterated urine by immunoassays and gas chromatography-mass spectrometry.
Topics: Amphetamine; Cocaine; Dronabinol; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Nitrites; Phencyclidine; Substance Abuse Detection; Sulfites | 1998 |
Regulation of tyrosine hydroxylase promoter activity by chronic morphine in TH9.0-LacZ transgenic mice.
Topics: Animals; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Gene Expression Regulation, Enzymologic; Lac Operon; Locus Coeruleus; Male; Mice; Mice, Transgenic; Morphine; Narcotics; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 1998 |
Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm.
Topics: Amphetamine; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward | 1998 |
Modulation of cocaine-induced antinociception by opioid-receptor agonists.
Topics: Analgesics; Animals; Benzeneacetamides; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Morphine; Pain; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa | 1999 |
Antinociceptive effects of cocaine in rhesus monkeys.
Topics: Analgesics; Analgesics, Opioid; Animals; Cocaine; Drug Interactions; Female; Macaca mulatta; Male; Mianserin; Morphine; Pain Measurement; Serotonin Antagonists | 1999 |
Opioids accelerate fetal rat lung maturation in vitro.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Heroin; In Vitro Techniques; Lung; Methadone; Morphine; Narcotics; Rats; Rats, Sprague-Dawley | 1999 |
Functional heterogeneity in dopamine release and in the expression of Fos-like proteins within the rat striatal complex.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Immunohistochemistry; Injections; Male; Morphine; Nerve Tissue Proteins; Pharmaceutical Vehicles; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 1999 |
Workplace drug testing: two cautionary cases.
Topics: Beverages; Cocaine; False Positive Reactions; Food Analysis; Hospitals, Veterans; Humans; Laboratories, Hospital; Morphine; Oregon; Papaver; Personnel, Hospital; Plants, Medicinal; Substance Abuse Detection; Workforce | 1994 |
Enhanced morphine- and cocaine-induced behavioral sensitization in alcohol-preferring AA rats.
Topics: Alcohol Drinking; Alcohols; Analgesics, Opioid; Analysis of Variance; Animals; Cocaine; Dopamine Uptake Inhibitors; Environment; Male; Morphine; Motor Activity; Rats; Rats, Wistar; Sodium Chloride | 1999 |
Reciprocal changes in dopamine responsiveness in the nucleus accumbens shell and core and in the dorsal caudate-putamen in rats sensitized to morphine.
Topics: Amphetamine; Animals; Catalepsy; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Grooming; Male; Microdialysis; Morphine; Morphine Dependence; Motor Activity; Nucleus Accumbens; Putamen; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome | 1999 |
Voluntary consumption of amphetamine, cocaine, ethanol and morphine by rats as influenced by a preceding period of forced drug intake and clozapine.
Topics: Administration, Oral; Amphetamine; Animals; Central Nervous System Depressants; Clozapine; Cocaine; Dopamine Agents; Ethanol; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders | 1999 |
The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat.
Topics: Animals; Central Nervous System Depressants; Cocaine; Corpus Striatum; Drug Administration Schedule; Ethanol; Male; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1999 |
Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, have a dopamine component in monkeys.
Topics: Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Dopamine; Dopamine Agonists; Dopamine Antagonists; Generalization, Stimulus; Male; Morphine; Neurons; Norepinephrine; Phencyclidine; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Saimiri; Selective Serotonin Reuptake Inhibitors; Triazoles | 1999 |
Discriminative stimulus effects of morphine in squirrel monkeys: stimulants, opioids, and stimulant-opioid combinations.
Topics: Amphetamine; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Anxiety Agents; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Fentanyl; Male; Morphine; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Opioid; Saimiri; Selective Serotonin Reuptake Inhibitors | 1999 |
Determination of opiates and cocaine in hair as trimethylsilyl derivatives using gas chromatography-tandem mass spectrometry.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Trimethylsilyl Compounds | 1999 |
The suppressive effects of LiCl, sucrose, and drugs of abuse are modulated by sucrose concentration in food-deprived rats.
Topics: Analysis of Variance; Animals; Appetite; Avoidance Learning; Cocaine; Conditioning, Classical; Dietary Sucrose; Dose-Response Relationship, Drug; Drinking Behavior; Food Deprivation; Food Preferences; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Taste | 1999 |
Immunoassay and GC-MS procedures for the analysis of drugs of abuse in meconium.
Topics: Amphetamine; Cocaine; Dronabinol; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Morphine; Narcotics; Phencyclidine; Pregnancy; Reproducibility of Results; Substance Abuse Detection | 1999 |
Acute injection of drugs with low addictive potential (delta(9)-tetrahydrocannabinol, 3,4-methylenedioxymethamphetamine, lysergic acid diamide) causes a much higher c-fos expression in limbic brain areas than highly addicting drugs (cocaine and morphine).
Topics: Animals; Cocaine; Dronabinol; Hallucinogens; Illicit Drugs; In Situ Hybridization; Limbic System; Lysergic Acid Diethylamide; Male; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar | 1999 |
Sensitization to daily morphine injections in rats with unilateral lesions of the substantia nigra.
Topics: Amphetamine; Analgesics, Opioid; Animals; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra | 1999 |
Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Excitatory Amino Acid Antagonists; Functional Laterality; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward; Stereotyped Behavior; Time Factors | 1999 |
Modulation of the discriminative stimulus effects of d-amphetamine by mu and kappa opioids in squirrel monkeys.
Topics: Animals; Benzeneacetamides; Benzofurans; Cocaine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Morphine; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri | 2000 |
Cocaine-opioid interactions in groups of rats trained to discriminate different doses of cocaine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Morphine; Narcotics; Rats; Rats, Wistar | 1999 |
Cocaine-seeking produced by experimenter-administered drug injections: dose-effect relationships in rats.
Topics: Animals; Caffeine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Male; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement Schedule | 1999 |
Screening postmortem blood and tissues for nine classes [correction of cases] of drugs of abuse using automated microplate immunoassay.
Topics: Amphetamine; Anti-Anxiety Agents; Autopsy; Benzodiazepines; Body Fluids; Cannabinoids; Central Nervous System Stimulants; Cocaine; Enzyme-Linked Immunosorbent Assay; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hypnotics and Sedatives; Illicit Drugs; Lysergic Acid Diethylamide; Methamphetamine; Microchemistry; Morphine; Narcotics; Phencyclidine; Radioimmunoassay; Sensitivity and Specificity; Substance-Related Disorders; Tissue Distribution | 1999 |
Differences in drug-induced place conditioning between BALB/c and C57Bl/6 mice.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Psychological; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Species Specificity | 2000 |
Simultaneous hair testing for opiates, cocaine, and metabolites by GC-MS: a survey of applicants for driving licenses with a history of drug use.
Topics: Automobile Driving; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Italy; Licensure; Morphine; Narcotics; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 2000 |
Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons after cocaine treatment.
Topics: Adenosine; Amphetamine; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrophysiology; Excitatory Postsynaptic Potentials; Male; Morphine; Narcotics; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synapses; Xanthines | 2000 |
Cocaine and morphine-induced place conditioning in adolescent and adult rats.
Topics: Aging; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Female; Male; Morphine; Rats; Rats, Sprague-Dawley; Sex Characteristics | 2000 |
NGFI-B and nor1 mRNAs are upregulated in brain reward pathways by drugs of abuse: different effects in Fischer and Lewis rats.
Topics: Animals; Brain; Cocaine; Corpus Striatum; DNA-Binding Proteins; Gyrus Cinguli; Male; Morphine; Narcotics; Nerve Tissue Proteins; Nuclear Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reward; RNA, Messenger; Species Specificity; Time Factors; Transcription Factors; Up-Regulation | 2000 |
Cytokine pattern secretion by murine spleen cells after inactivated Candida albicans immunization. Effect of cocaine and morphine treatment.
Topics: Animals; Antigens, Fungal; Candida albicans; Cells, Cultured; Cocaine; Cytokines; Enzyme-Linked Immunosorbent Assay; Immunization; Interferon-gamma; Interleukin-2; Interleukin-4; Male; Mice; Mice, Inbred BALB C; Morphine; Narcotics; Spleen | 2000 |
Role for GDNF in biochemical and behavioral adaptations to drugs of abuse.
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Glial Cell Line-Derived Neurotrophic Factor; Illicit Drugs; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Narcotics; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2000 |
Drug deposition in adipose tissue and skin: evidence for an alternative source of positive sweat patch tests.
Topics: Adipose Tissue; Cocaine; Cocaine-Related Disorders; Deuterium; Gas Chromatography-Mass Spectrometry; Heroin; Heroin Dependence; Humans; Illicit Drugs; Male; Morphine; Narcotics; Opioid-Related Disorders; Radiopharmaceuticals; Skin; Substance Abuse Detection; Sweat | 2000 |
Prior experience of morphine application alters the c-fos response to MDMA ('ecstasy') and cocaine in the rat striatum.
Topics: Animals; Cocaine; Corpus Striatum; Gene Expression Regulation; Genes, fos; Lysergic Acid Diethylamide; Male; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Transcription, Genetic | 2000 |
The discriminative stimulus effects of morphine in pigeons responding under a progressive ratio schedule of food presentation.
Topics: Animals; Buprenorphine; Cocaine; Columbidae; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Food; Morphine; Nalbuphine; Narcotic Antagonists; Narcotics; Reinforcement Schedule; Time Factors | 2000 |
Rewarding effects of opiates are absent in mice lacking the receptor for substance P.
Topics: Animals; Cocaine; Conditioning, Classical; Corpus Striatum; Cyclic AMP; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Morphine Dependence; Narcotics; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Neurokinin-1; Receptors, Opioid, mu; Reward | 2000 |
Effects of the non-competitive NMDA-receptor antagonist memantine on morphine- and cocaine-induced potentiation of lateral hypothalamic brain stimulation reward.
Topics: Analgesics, Opioid; Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; Memantine; Morphine; Rats; Rats, Long-Evans; Reward | 2000 |
Sexual assault under benzodiazepine submission in a Paris suburb.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dronabinol; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunoassay; Lorazepam; Male; Morphine; Narcotics; Nitrazepam; Paris; Rape; Retrospective Studies; Substance-Related Disorders; Temazepam; Time Factors; Triazolam | 2000 |
Verification of the drug history given by potential blood donors: results of drug screening that combines hair and urine analysis.
Topics: Adolescent; Adult; Amphetamines; Blood Donors; Cannabinoids; Cocaine; Communicable Diseases; Deception; Female; Germany; Hair; Humans; Male; Mass Screening; Medical History Taking; Morphine; Risk Factors; Substance Abuse Detection; Substance-Related Disorders; Surveys and Questionnaires; Truth Disclosure; Urine | 2000 |
Effects of cocaine and morphine under mixed-ratio schedules of food delivery: support for a behavioral momentum analysis.
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Drug Tolerance; Female; Food; Morphine | 2000 |
Development of novel medications for drug addiction. The legacy of an African shrub.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Ibogaine; Morphine; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders | 2000 |
Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs.
Topics: Animals; Blood Platelets; Brain; Cocaine; Collagen; Cyclic AMP; Epinephrine; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins; Humans; Lung; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Platelet Activation; Platelet Aggregation; Psychotropic Drugs; Signal Transduction; Thromboembolism | 2000 |
Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen.
Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Gene Expression; In Situ Hybridization; Male; Morphine; Naloxone; Narcotic Antagonists; Neostriatum; Rats; Rats, Inbred F344; Rats, Inbred Lew; RNA, Messenger; Running; Species Specificity; Substance P | 2000 |
Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs.
Topics: Analysis of Variance; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Extracellular Space; Illicit Drugs; Male; Microdialysis; Morphine; Nicotine; Piperazines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Synaptic Transmission | 2000 |
Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice.
Topics: Animals; Avoidance Learning; Cannabinoids; Cocaine; Drug Administration Schedule; Exploratory Behavior; Injections, Intraperitoneal; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Receptors, Cannabinoid; Receptors, Drug; Reward | 2000 |
18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ibogaine; In Vitro Techniques; Morphine; Psychopharmacology; Self Administration; Substance Withdrawal Syndrome | 2000 |
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Addictive; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Knockout; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, Cannabinoid; Receptors, Drug; Reward | 2001 |
Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum.
Topics: Adrenalectomy; Animals; Benzazepines; Biomarkers; Cocaine; Corpus Striatum; Corticosterone; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Extracellular Space; Gene Expression Regulation; Genes, fos; Male; Microdialysis; Morphine; Nerve Tissue Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereotaxic Techniques; Synaptic Transmission; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2001 |
The effects of chronic morphine on behavior reinforced by several opioids or by cocaine in rhesus monkeys.
Topics: Alfentanil; Analgesics, Opioid; Animals; Buprenorphine; Cocaine; Dopamine Uptake Inhibitors; Drug Tolerance; Heroin; Macaca mulatta; Male; Morphine; Nalbuphine; Reaction Time; Reinforcement, Psychology | 2001 |
Evaluation of immunoassays for semiquantitative detection of cocaine and metabolites or heroin and metabolites in extracts of sweat patches.
Topics: Cocaine; Heroin; Humans; Immunoenzyme Techniques; Morphine; Morphine Derivatives; Narcotics; Radioimmunoassay; Substance Abuse Detection; Sweat | 2001 |
A survey of extraction techniques for drugs of abuse in urine.
Topics: Amphetamines; Chi-Square Distribution; Cocaine; Humans; Laboratories; Morphine; Narcotics; Quality Assurance, Health Care; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Surveys and Questionnaires; United Kingdom | 2001 |
Repeated cocaine administration does not alter morphine-induced rotational behavior in nigrally denervated rats.
Topics: Animals; Brain Mapping; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra | 2001 |
Analysis of cocaine, benzoylecgonine, codeine, and morphine in hair by supercritical fluid extraction with carbon dioxide modified with methanol.
Topics: Carbon Dioxide; Chromatography; Cocaine; Codeine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methanol; Morphine; Reference Standards; Reproducibility of Results | 2001 |
Temporal factors affecting cocaine-opioid interactions: a cocaine drug discrimination study in rats.
Topics: Analgesics, Opioid; Animals; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, mu | 2001 |
Effects of strain, behavior and age on the self-administration of ethanol, nicotine, cocaine and morphine by two rat strains.
Topics: Administration, Oral; Aging; Animals; Behavior, Animal; Cocaine; Ethanol; Male; Morphine; Nicotine; Rats; Rats, Inbred BN; Rats, Inbred Strains; Rats, Inbred WKY; Self Administration | 2001 |
Mouse strain differences in opiate reward learning are explained by differences in anxiety, not reward or learning.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Cues; Diazepam; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Modulators; Learning; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Motivation; Naloxone; Narcotics; Pentobarbital; Phenotype; Reward; Species Specificity | 2001 |
Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.
Topics: Alleles; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Crosses, Genetic; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Disease Susceptibility; Drug Implants; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Morphine Dependence; Motivation; Motor Activity; Narcotic Antagonists; Phenotype; Protein Isoforms; Reinforcement, Psychology; Response Elements; Spatial Behavior | 2001 |
In vitro response of v-Ha-ras transgenic mouse lymphocytes after in vivo treatment with alcohol.
Topics: Animals; Cocaine; Enzyme-Linked Immunosorbent Assay; Ethanol; Female; Genes, ras; In Vitro Techniques; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred Strains; Mice, Transgenic; Morphine; Spleen; Thymus Gland | 2001 |
In vitro response of v-Ha-ras transgenic mouse lymphocytes after in vivo treatment with cocaine.
Topics: Animals; Cocaine; Enzyme-Linked Immunosorbent Assay; Female; Genes, ras; In Vitro Techniques; Injections, Intraperitoneal; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred Strains; Mice, Transgenic; Morphine; Spleen; Thymus Gland | 2001 |
Repeated social-defeat stress, cocaine or morphine. Effects on behavioral sensitization and intravenous cocaine self-administration "binges".
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Corticosterone; Dextroamphetamine; Dominance-Subordination; Female; Injections, Intravenous; Male; Morphine; Narcotics; Rats; Rats, Long-Evans; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Stress, Psychological | 2001 |
Dizocilpine infusion has a different effect in the development of morphine and cocaine sensitization: behavioral and neurochemical aspects.
Topics: Animals; Blotting, Western; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Hippocampus; Limbic System; Male; Morphine; Morphine Dependence; Nucleus Accumbens; Pain Measurement; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2002 |
Voluntary self-administration of both morphine and cocaine by rats.
Topics: Administration, Oral; Animals; Cocaine; Drug Combinations; Drug Interactions; Male; Morphine; Rats; Rats, Sprague-Dawley; Self Administration | 2002 |
Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels.
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Cannabinoids; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Ethanol; Injections, Intraperitoneal; Male; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; RNA, Messenger | 2002 |
Conditioning tastant and the acquisition of conditioned taste avoidance to drugs of abuse in DBA/2J mice.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Ethanol; Illicit Drugs; Lithium; Male; Mice; Mice, Inbred DBA; Morphine; Saccharin; Sodium Chloride; Taste | 2002 |
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System Stimulants; Choice Behavior; Cocaine; Crosses, Genetic; Dextroamphetamine; Dopamine; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Muscarinic Antagonists; Narcotics; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward; Substance-Related Disorders; Synaptic Transmission | 2002 |
Changes in extracellular dopamine induced by morphine and cocaine: crucial control by D2 receptors.
Topics: Animals; Autoreceptors; Cocaine; Corpus Striatum; Crosses, Genetic; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Extracellular Space; Medial Forebrain Bundle; Mice; Mice, Inbred Strains; Mice, Knockout; Microdialysis; Morphine; Narcotics; Protein Isoforms; Receptors, Dopamine D2 | 2002 |
Toxic effects of opioid and stimulant drugs on undifferentiated PC12 cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Survival; Chromatin; Cocaine; Dextroamphetamine; Dopamine; Heroin; L-Lactate Dehydrogenase; Models, Animal; Morphine; Narcotics; PC12 Cells; Pheochromocytoma; Rats; Reactive Oxygen Species | 2002 |
Therapeutic drugs and death.
Topics: Aged; Analgesics, Opioid; Anesthetics, Local; Anti-Anxiety Agents; Cocaine; Drug Overdose; Fatal Outcome; Female; Humans; Male; Medication Errors; Midazolam; Morphine; Victoria | 2001 |
Sensitization does not develop to cocaine-induced potentiation of the antinociceptive effect of morphine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hot Temperature; Male; Morphine; Motor Activity; Narcotics; Nociceptors; Rats; Rats, Sprague-Dawley | 2002 |
Rotational behaviour in AA and ANA rats after repeated administration of morphine and cocaine.
Topics: Alcohol Drinking; Animals; Cocaine; Dose-Response Relationship, Drug; Male; Morphine; Narcotics; Oxidopamine; Rats; Rotation; Stereotaxic Techniques; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2002 |
Does reduced DNA repair capacity play a role in HIV infection and progression in the lymphocytes of opiate addicts?
Topics: Cocaine; DNA Repair; Heroin; HIV Infections; HIV-1; Humans; Lymphocytes; Morphine; Mutation; Narcotics; Opioid-Related Disorders; Ultraviolet Rays | 2002 |
Morphine, cocaine and antidepressant induced motivational activity and midbrain dopaminergic neurotransmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Mesencephalon; Morphine; Motivation; Nucleus Accumbens; Paroxetine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Sertraline | 2002 |
Molecular and behavioral interactions between central melanocortins and cocaine.
Topics: alpha-MSH; Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Grooming; In Situ Hybridization; Injections, Intraventricular; Kinetics; Male; Morphine; Motor Activity; Neostriatum; Nuclease Protection Assays; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin; Receptors, Dopamine; Receptors, Melanocortin; Up-Regulation | 2003 |
The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.
Topics: Amphetamine; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Illicit Drugs; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Narcotics; Nicotine; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward | 2003 |
Central serotonin4 receptors selectively regulate the impulse-dependent exocytosis of dopamine in the rat striatum: in vivo studies with morphine, amphetamine and cocaine.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Exocytosis; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine.
Topics: Acamprosate; Alcohol Deterrents; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Secondary Prevention; Taurine | 2003 |
Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Receptors, Neurokinin-1; Self Administration | 2002 |
Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electrochemistry; Haloperidol; Male; Microdialysis; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT3 Receptor Antagonists; Tropanes | 2003 |
Intravenous drug injection habits: drug users' self-reports versus researchers' perception.
Topics: Adult; Cocaine; Female; Heroin; Humans; Male; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Outpatients; Research Personnel; Substance Abuse, Intravenous; Substance-Related Disorders; Surveys and Questionnaires; Time Factors | 2003 |
Cross-sensitization between the locomotor stimulant effects of ethanol and those of morphine and cocaine in mice.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Female; Mice; Morphine; Motor Activity | 2003 |
Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Donepezil; Indans; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Nucleus Accumbens; Pain; Piperidines; Substance Withdrawal Syndrome | 2003 |
Methadone substitution: medicolegal problems in Germany.
Topics: Adolescent; Adult; Amphetamines; Antidepressive Agents; Automobile Driving; Benzodiazepines; Cannabinoids; Cocaine; Drug and Narcotic Control; Ethanol; Female; Forensic Medicine; Germany; Humans; Male; Methadone; Middle Aged; Morphine; Narcotics; Practice Patterns, Physicians'; Substance-Related Disorders | 2003 |
Morphine and cocaine influence on CRF biosynthesis in the rat central nucleus of amygdala.
Topics: Amygdala; Analgesics, Opioid; Animals; Cocaine; Corticotropin-Releasing Hormone; Immunohistochemistry; In Situ Hybridization; Injections, Intraperitoneal; Male; Morphine; Rats; Rats, Wistar; RNA, Messenger; Substance Withdrawal Syndrome | 2003 |
Opioids, cocaine, and food change runtime distribution in a rat runway procedure.
Topics: Alfentanil; Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Milk; Morphine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement, Psychology; Remifentanil | 2003 |
Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice.
Topics: Adaptation, Physiological; Animals; Cocaine; Dopamine Uptake Inhibitors; Mice; Mice, Knockout; Morphine; Motor Activity; Narcotics; Receptors, Opioid, mu | 2003 |
Augmented responses to morphine and cocaine in mice with a 12-lipoxygenase gene disruption.
Topics: Anesthetics, Local; Animals; Arachidonate 12-Lipoxygenase; Avoidance Learning; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Tolerance; Inhibition, Psychological; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Mutation; Narcotics; Pain Threshold; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance Withdrawal Syndrome; Swimming | 2003 |
Segregation of amphetamine reward and locomotor stimulation between nucleus accumbens medial shell and core.
Topics: Amphetamine; Animals; Autoradiography; Behavior, Animal; Binding, Competitive; Carrier Proteins; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morphine; Motor Activity; Narcotics; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Oxidopamine; Rats; Rats, Long-Evans; Reward; Serotonin Plasma Membrane Transport Proteins; Spatial Behavior | 2003 |
Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat.
Topics: Animals; Baclofen; Cocaine; Dopamine; Dose-Response Relationship, Drug; Extracellular Fluid; GABA Agonists; GABA-B Receptor Agonists; Male; Microdialysis; Morphine; Neural Pathways; Nicotine; Nucleus Accumbens; Rats; Receptors, GABA-B; Reward; Substance-Related Disorders; Synaptic Transmission; Up-Regulation | 2003 |
Effects of a dopamine D3 receptor ligand, BP 897, on acquisition and expression of food-, morphine-, and cocaine-induced conditioned place preference, and food-seeking behavior in rats.
Topics: Animals; Behavior, Addictive; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Feeding Behavior; Male; Morphine; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3 | 2003 |
Psychoactive drugs and quality of life.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphetamines; Cocaine; Cohort Studies; Data Collection; Hallucinogens; Heroin; Humans; Marijuana Abuse; Methadone; Middle Aged; Morphine; Psychotropic Drugs; Quality of Life; Stimulants, Historical; Substance-Related Disorders; Surveys and Questionnaires | 2003 |
Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Psychological; Crosses, Genetic; Drug Administration Routes; Illicit Drugs; Immunotoxins; Male; Maze Learning; Mice; Mice, Inbred Strains; Mice, Knockout; Morphine; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Receptors, Neurokinin-1; Reward; Ribosome Inactivating Proteins, Type 1; Saporins; Spatial Behavior; Substance P | 2003 |
Retention of sequential drug discriminations under fixed-interval schedules for long time periods without training.
Topics: Animals; Behavior, Animal; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Chlordiazepoxide; Cocaine; Columbidae; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Generalization, Psychological; Male; Morphine; Nicotine; Pentobarbital; Reinforcement Schedule | 2003 |
[Pharmacological influencing of stimulus transmission in intestines].
Topics: Atropine; Biological Phenomena; Cocaine; Hexamethonium Compounds; Intestines; Morphine; Physiological Phenomena | 1956 |
Two kinds of tryptamine receptor.
Topics: Alkaloids; Atropine; Carbohydrate Metabolism; Carbohydrates; Cocaine; Guinea Pigs; Ileum; Indoles; Lysergic Acid Diethylamide; Morphine; Phenoxybenzamine; Receptors, Serotonin; Serotonin | 1957 |
[The effect of various pharmacological agents (amphetamine, cocaine, caffeine, hexobarbital, meprobamate, morphine, dextromoramide, 1-methadone, pethidine and CT 3570) on the time of exhaustion and behavior of animals swimming at 20 degrees C].
Topics: Amphetamine; Amphetamines; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Behavior; Caffeine; Central Nervous System Stimulants; Cocaine; Dextromoramide; Hexobarbital; Hypnotics and Sedatives; Meperidine; Meprobamate; Methadone; Morphine; Physical Exertion; Swimming; Tomography, X-Ray Computed | 1960 |
Effect of morphine on some sympathetically innervated effectors.
Topics: Animals; Autonomic Nervous System; Cats; Cocaine; Morphine; Musculoskeletal Physiological Phenomena; Nerve Endings; Nictitating Membrane; Norepinephrine; Sympathetic Fibers, Postganglionic; Sympathetic Nervous System | 1961 |
[What place do morphine and cocaine occupy in the arsenal of so-called psychopharmacological drugs? Experimental study].
Topics: Cocaine; Morphine; Psychopharmacology | 1961 |
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental | 1962 |
[Studies on the effect of putrefaction on the recovery of alkaloids from corpses].
Topics: Alkaloids; Atropine; Cadaver; Cocaine; Humans; Morphine; Strychnine | 1962 |
GANGLIONIC ACTIONS OF MUSCARINIC SUBSTANCES.
Topics: Animals; Atropine; Autonomic Nervous System; Cats; Cholinergic Agents; Cocaine; Ganglia; Ganglia, Autonomic; Ganglionic Blockers; Hexamethonium Compounds; Methadone; Morphine; Nicotine; Nictitating Membrane; Parasympathomimetics; Pharmacology; Research | 1963 |
EFFECT OF DRUGS ON CONDITIONED AVOIDANCE RESPONSE IN RATS.
Topics: Avoidance Learning; Chlordiazepoxide; Chlorpromazine; Cocaine; Codeine; Conditioning, Operant; Ethanol; Hydroxyzine; Meperidine; Methylphenidate; Morphine; Pharmacology; Promethazine; Rats; Research; Sodium Salicylate | 1963 |
ACETYLCHOLINE-RELEASING MATERIAL IN NEURAL TISSUES.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Cocaine; Ganglionic Blockers; Guinea Pigs; Hexamethonium Compounds; Histamine H1 Antagonists; Hot Temperature; Hypoxia; Ileum; Lysergic Acid Diethylamide; Morphine; Pharmacology; Rabbits; Research; Sciatic Nerve; Swine; Tetraethylammonium Compounds; Tissue Extracts | 1963 |
THE INFLUENCE OF NARCOTICS ON SOME AGE-ASSOCIATED CHANGES IN AEROBACTER AEROGENES.
Topics: Barbiturates; Cocaine; Codeine; Enterobacter aerogenes; Morphine; Narcotics; Pharmacology; Procaine; Research; Strychnine | 1964 |
THE PRESENCE IN SCIATIC NERVE OF MATERIAL THAT RELEASES ACETYLCHOLINE.
Topics: Acetylcholine; Acetylcholinesterase; Atropine; Cocaine; Guinea Pigs; Hexamethonium Compounds; Ileum; Morphine; Pharmacology; Physiology; Rabbits; Research; Sciatic Nerve; Tetraethylammonium Compounds; Tissue Extracts | 1964 |
STATISTICS AS APPLIED TO PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING.
Topics: Arsphenamine; Atropine; Biological Assay; Biometry; Cocaine; Digoxin; Epinephrine; Ergonovine; Ergot Alkaloids; Hexamethonium Compounds; Histamine; Insulin; Meperidine; Methadone; Morphine; Pharmacology; Promethazine; Research; Riboflavin; Statistics as Topic; Strophanthins; Toxicology; Tubocurarine | 1963 |
[TOXICOPHILIA MEDICAMENTOSA].
Topics: Barbiturates; Cannabis; Cocaine; Humans; Morphine; Substance-Related Disorders; Toxicology | 1964 |
MECHANISM OF CARDIAC ACTIVITIES SYMPATHOMIMETIC AMINES ON ISOLATED AURICLES OF RABBITS.
Topics: Amphetamine; Amphetamines; Bretylium Compounds; Cocaine; Dopamine; Ephedrine; Epinephrine; Ethers; Heart; Hexamethonium Compounds; Isoproterenol; Metabolism; Morphine; Norepinephrine; Pharmacology; Phenethylamines; Phenylephrine; Rabbits; Research; Sympathomimetics; Synephrine; Tyramine | 1964 |
GAS CHROMATOGRAPHY OF HIGH-BOILING AMINES. II. DETERMINATION OF AMINES IN LOW CONCENTRATION.
Topics: Amines; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cocaine; Codeine; Ephedrine; Lidocaine; Methadone; Morphine; Pharmacy; Promazine; Research; Scopolamine | 1964 |
FACTORS MODIFYING CHLORPROMAZINE HYPERTHERMIA IN YOUNG ALBINO MICE.
Topics: Amphetamine; Amphetamines; Animals; Chlorpromazine; Cocaine; Cyanides; Fever; Insulin; Iproniazid; Lysergic Acid Diethylamide; Mice; Morphine; Nalorphine; Pharmacology; Pilocarpine; Research; Reserpine; Tripelennamine; Tubocurarine | 1965 |
A METHOD FOR THE THIN-LAYER CHROMATOGRAPHY OF ANALGESIC DRUGS AND RELATED COMPOUNDS IN NON-AQUEOUS SYSTEMS.
Topics: Ammonia; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Azepines; Chromatography; Chromatography, Thin Layer; Cocaine; Codeine; Dextropropoxyphene; Isonipecotic Acids; Meperidine; Methadone; Morphine; Research | 1965 |
[USE OF THE CRYSTALLO-OPTIC METHOD IN THE STUDY OF SYNTHETIC SUBSTITUTES FOR COCAINE, MORPHINE AND ATROPINE].
Topics: Atropine; Cocaine; Crystallography; Morphine; Research | 1964 |
Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-kappaB in transiently cotransfected heart cells.
Topics: Acetylcysteine; Animals; Cells, Cultured; Cocaine; Dose-Response Relationship, Drug; Free Radicals; Genes, Reporter; Glutathione; Morphine; Myocytes, Cardiac; Narcotics; NF-kappa B; Rats; Reactive Oxygen Species; Signal Transduction; Thioctic Acid; Transfection | 2003 |
Dopamine responsiveness to drugs of abuse: A shell-core investigation in the nucleus accumbens of the mouse.
Topics: Amphetamine; Anesthetics, Local; Animals; Calbindins; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Disease Models, Animal; Dopamine; Ethanol; Extracellular Space; Illicit Drugs; Immunohistochemistry; Male; Mice; Microdialysis; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; S100 Calcium Binding Protein G; Substance-Related Disorders; Time Factors | 2003 |
Cocaine and other indirect-acting monoamine agonists differentially attenuate a naltrexone discriminative stimulus in morphine-treated rhesus monkeys.
Topics: Amphetamine; Animals; Biogenic Monoamines; Cocaine; Discrimination Learning; Disease Models, Animal; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Imipramine; Macaca mulatta; Morphine; Morphine Dependence; Naltrexone; Narcotics; Substance Withdrawal Syndrome | 2004 |
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
Topics: Animals; Arrestins; Behavior, Animal; beta-Arrestin 2; beta-Arrestins; Cocaine; Corpus Striatum; Dopamine; Male; Mice; Mice, Knockout; Microdialysis; Morphine; Motor Activity; Reward; Spatial Behavior | 2003 |
Differential distribution of CREB in the mesolimbic dopamine reward pathway.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA; Dopamine; Dynorphins; Illicit Drugs; Limbic System; Mice; Mice, Mutant Strains; Morphine; Neural Pathways; Nucleus Accumbens; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Reward; Substance-Related Disorders; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2003 |
Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine.
Topics: Amidines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dialysis; Dopamine; Dose-Response Relationship, Drug; Food; Male; Morphine; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors; Vasoconstrictor Agents | 2003 |
Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Naloxone; Nociceptin; Opioid Peptides | 2004 |
Up-regulation of murine double minute clone 2 (MDM2) gene expression in rat brain after morphine, heroin, and cocaine administrations.
Topics: Animals; Brain; Cocaine; Heroin; Male; Mice; Morphine; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Up-Regulation | 2003 |
Opioid partial agonist effects of 3-O-methylnaltrexone in rhesus monkeys.
Topics: Adenylyl Cyclases; Animals; Cocaine; Discrimination Learning; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Heroin Dependence; Macaca mulatta; Male; Morphine; Morphine Derivatives; Naltrexone; Narcotics; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Self Administration | 2004 |
The effect of drugs of abuse on NMDAR1 receptor expression in the rat limbic system.
Topics: Amygdala; Animals; Cocaine; Drug Administration Schedule; Hippocampus; In Situ Hybridization; Limbic System; Male; Morphine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Time Factors | 2003 |
Optimized conditions for simultaneous determination of opiates, cocaine and benzoylecgonine in hair samples by GC--MS.
Topics: Adolescent; Adult; Buffers; Case-Control Studies; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Phosphates; Substance-Related Disorders | 2003 |
Differences in morphine and cocaine reinforcement under fixed and progressive ratio schedules; effects of extinction, reacquisition and schedule design.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Morphine; Narcotics; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration | 2003 |
Demographic, pathologic, and toxicological profiles of 127 decedents testing positive for ephedrine alkaloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Child, Preschool; Cocaine; Coronary Artery Disease; Dietary Supplements; Dopamine Uptake Inhibitors; Ephedrine; Fatty Liver; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Morphine; Narcotics; Nephrosclerosis; Phenylpropanolamine; Racial Groups; Sex Distribution; Sympathomimetics; Wounds and Injuries | 2004 |
Morphine- and cocaine-induced c-Fos levels in Lewis and Fischer rat strains.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Brain; Cocaine; Female; Immunohistochemistry; Morphine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Rats, Inbred Lew; Species Specificity | 2004 |
Immune cell activity during the initial stages of withdrawal from chronic exposure to cocaine or morphine.
Topics: Analysis of Variance; Animals; Cocaine; Concanavalin A; Corticosterone; Lymphocytes; Male; Mitogens; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thymidine; Time Factors; Tritium | 2004 |
Effects of morphine and cocaine in mice with stable high aggressive and nonaggressive behavioral strategy.
Topics: Aggression; Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Morphine; Pain Measurement; Phenotype; Reinforcement, Psychology; Self Administration; Social Behavior; Social Dominance | 2004 |
Analytic performance of immunoassays for drugs of abuse below established cutoff values.
Topics: Cocaine; Dextroamphetamine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Morphine; Narcotics; Phencyclidine; Predictive Value of Tests; Sensitivity and Specificity; Substance Abuse Detection | 2004 |
A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Environment; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Ventral Tegmental Area | 2004 |
Simultaneous detection and quantitation of morphine, 6-acetylmorphine, and cocaine in toenails: comparison with hair analysis.
Topics: Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Nails; Substance Abuse Detection; Substance-Related Disorders | 2004 |
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors | 2004 |
The Type IV phosphodiesterase inhibitor rolipram interferes with drug-induced conditioned place preference but not immediate early gene induction in mice.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Basal Ganglia; Cell Count; Cocaine; Conditioning, Operant; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Male; Mice; Morphine; Phosphodiesterase Inhibitors; Proto-Oncogene Proteins c-fos; Rolipram; Transcriptional Activation | 2004 |
DREAM ablation selectively alters THC place aversion and analgesia but leaves intact the motivational and analgesic effects of morphine.
Topics: Analgesia; Analgesics; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Dronabinol; Lithium Chloride; Male; Mice; Mice, Knockout; Morphine; Motivation; Motor Activity; Naloxone; Narcotic Antagonists; Reaction Time; Repressor Proteins; Substance Withdrawal Syndrome; Transcription Factors | 2004 |
Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons.
Topics: Action Potentials; Age Factors; Amphetamine; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Critical Period, Psychological; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Electrophysiology; Illicit Drugs; Male; Morphine; Morpholines; Naphthalenes; Nerve Net; Neurons; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Ventral Tegmental Area | 2004 |
The basolateral complex of the amygdala mediates the modulation of intracranial self-stimulation threshold by drug-associated cues.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Discrimination Learning; Male; Morphine; Rats; Rats, Long-Evans; Reward; Self Stimulation | 2004 |
Chronic opiate treatment enhances both cocaine-reinforced and cocaine-seeking behaviors following opiate withdrawal.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Male; Morphine; Narcotics; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome | 2004 |
Dopamine and cyclic AMP-regulated phosphoprotein-32 phosphorylation pattern in cocaine and morphine-sensitized rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dopamine and cAMP-Regulated Phosphoprotein 32; Male; Morphine; Morphine Dependence; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2004 |
Chronic morphine treatment reduces recovery from opioid desensitization.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Cocaine; Drug Tolerance; Enkephalin, Methionine; Leucine; Locus Coeruleus; Male; Monensin; Morphine; Morphine Dependence; Morphine Derivatives; Norepinephrine; Phosphorylation; Prazosin; Protein Kinase C; Protein Processing, Post-Translational; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Staurosporine; Thiorphan; Yohimbine | 2004 |
Removing and identifying drug contamination in the analysis of human hair.
Topics: Cocaine; Decontamination; Dopamine Uptake Inhibitors; Forensic Medicine; Hair; Hallucinogens; Humans; Methamphetamine; Morphine; Morphine Derivatives; Narcotics; Phencyclidine; Solvents; Substance Abuse Detection; Sweat | 2004 |
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cotinine; Diazepam; Dopamine Uptake Inhibitors; Drug Overdose; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Narcotics; Nicotine; Nicotinic Agonists; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2004 |
[Regulation of G protein-coupled receptor kinase 5 mRNA and protein level in rat brain by addictive drugs].
Topics: Animals; Brain; Cocaine; G-Protein-Coupled Receptor Kinase 5; Heroin; Male; Morphine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance-Related Disorders | 2004 |
Lithium-chloride-induced conditioned taste aversions in the Lewis and Fischer 344 rat strains.
Topics: Animals; Cocaine; Conditioning, Psychological; Female; Lithium Chloride; Morphine; Rats; Rats, Inbred F344; Rats, Inbred Lew; Saccharin; Species Specificity; Substance-Related Disorders; Sweetening Agents; Taste | 2004 |
Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine.
Topics: Animals; Body Weight; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Learning; Male; Morphine; Motor Activity; Narcotic Antagonists; Narcotics; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Reward | 2004 |
Effects of morphine or naloxone on cocaine-induced genital reflexes in paradoxical sleep-deprived rats.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Wistar; Sexual Behavior, Animal; Sleep, REM | 2004 |
Effect of MS-153, a glutamate transporter activator, on the conditioned rewarding effects of morphine, methamphetamine and cocaine in mice.
Topics: Amino Acid Transport System X-AG; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Male; Methamphetamine; Mice; Morphine; Motor Activity; Narcotics; Nicotinic Acids; Reward; Time Factors | 2005 |
Combined effects of psychostimulants and morphine on locomotor activity in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Methamphetamine; Mice; Morphine; Motor Activity | 2004 |
Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine.
Topics: Animals; Cerebral Cortex; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Male; Morphine; Pregnanolone; Rats; Rats, Sprague-Dawley | 2005 |
Cross-sensitization to morphine in cocaine-sensitized rats: behavioral assessments correlate with enhanced responding of ventral pallidal neurons to morphine and glutamate, with diminished effects of GABA.
Topics: Action Potentials; Animals; Behavior, Animal; Cocaine; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Male; Morphine; Motor Activity; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2005 |
The accidental addict.
Topics: Anesthetics, Local; Baltimore; Cocaine; Cocaine-Related Disorders; General Surgery; History, 19th Century; History, 20th Century; Hospitals, University; Humans; Male; Morphine; Opioid-Related Disorders; United States | 2005 |
Repeated-testing of place preference expression for evaluation of anti-craving-drug effects.
Topics: Acamprosate; Alcohol Deterrents; Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Drug Evaluation, Preclinical; Male; Morphine; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Taurine | 2005 |
Effects of seven drugs of abuse on action potential repolarisation in sheep cardiac Purkinje fibres.
Topics: Action Potentials; Animals; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Illicit Drugs; In Vitro Techniques; Male; Methamphetamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Purkinje Fibers; Sheep; Time Factors | 2005 |
Isotope ratio mass spectrometry: delta13C and delta15 N analysis for tracing the origin of illicit drugs.
Topics: Afghanistan; Cannabis; Carbon Isotopes; Cocaine; Colombia; Drug Contamination; Gas Chromatography-Mass Spectrometry; Heroin; Illicit Drugs; Korea; Morphine; Nitrogen Isotopes; Russia; Ukraine | 2005 |
Maintenance of conditioned place preferences and aversion in C57BL6 mice: effects of repeated and drug state testing.
Topics: Anesthetics, Local; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Drug Administration Schedule; Extinction, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Substance Withdrawal Syndrome; Time Factors | 2005 |
Susceptibility to conditioned place preference induced by addictive drugs in mice of the C57BL/6 and DBA/2 inbred strains.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Hyperkinesis; Illicit Drugs; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Species Specificity | 2005 |
Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Blotting, Western; Carnitine Acyltransferases; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Extinction, Psychological; Food; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Microinjections; Mitochondrial Proteins; Morphine; Motor Activity; Narcotic Antagonists; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Somatostatin; Time Factors | 2005 |
Direct injection determination of benzoylecgonine, heroin, 6-monoacetylmorphine and morphine in serum by MLC.
Topics: Chromatography, Liquid; Cocaine; Heroin; Micelles; Morphine; Morphine Derivatives; Reproducibility of Results; Sensitivity and Specificity | 2005 |
DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment.
Topics: Animals; Cocaine; Cocaine-Related Disorders; gamma-Aminobutyric Acid; Kinetics; Male; Morphine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Self Administration; Transcription Factors; Ventral Tegmental Area | 2005 |
Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Female; Green Fluorescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Narcotics; Neurons; Nucleus Accumbens; Receptors, AMPA; Recombinant Fusion Proteins; Reward; Transcription, Genetic; Tyrosine 3-Monooxygenase; Up-Regulation; Ventral Tegmental Area | 2005 |
Cross-reinstatement by cocaine and amphetamine of morphine-induced place preference in mice.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Mice; Morphine; Narcotics; Reinforcement, Psychology | 2005 |
The role of cocaine in heroin-related deaths. Hypothesis on the interaction between heroin and cocaine.
Topics: Adolescent; Adult; Bile; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Ethanol; Female; Forensic Medicine; Heroin; Heroin Dependence; Humans; Male; Morphine; Narcotics; Substance Abuse Detection | 2005 |
Morphine tolerance as a function of ratio schedule: response requirement or unit price?
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Methadone; Morphine; Narcotics; Reinforcement Schedule; Reinforcement, Psychology | 2005 |
Kindling modifies morphine, cocaine and ethanol place preference.
Topics: Animals; Behavior, Animal; Body Temperature; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Convulsants; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Ethanol; Kindling, Neurologic; Male; Morphine; Motor Activity; Narcotics; Pentylenetetrazole; Rats; Rats, Wistar; Sucrose; Time Factors | 2006 |
NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice.
Topics: Amphetamine-Related Disorders; Animals; Blotting, Northern; Brain Chemistry; Cell Adhesion Molecules; Chromosome Mapping; Cloning, Molecular; Cocaine; Cocaine-Related Disorders; DNA, Complementary; Gene Expression Regulation; Genome, Human; Genotype; Haplotypes; Humans; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; RNA, Messenger; Substance-Related Disorders | 2006 |
Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway.
Topics: Analgesics, Opioid; Animals; Area Under Curve; Behavior, Animal; Cannabinoids; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine; Drug Administration Routes; Drug Interactions; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Neural Pathways; Piperidines; Pyrazoles; Rats; Rats, Wistar; Reinforcement, Psychology; Rimonabant; Self Administration; Time Factors | 2006 |
Apparatus bias and the use of light and texture in place conditioning.
Topics: Animals; Cocaine; Conditioning, Psychological; Female; Light; Morphine; Rats; Rats, Sprague-Dawley | 2005 |
Pharmacological action of Panax ginseng on the behavioral toxicities induced by psychotropic agents.
Topics: Animals; Behavior; Cocaine; Conditioning, Psychological; Ginsenosides; Humans; Methamphetamine; Morphine; Panax; Psychotropic Drugs | 2005 |
Use of drugs of abuse in less than 30-year-old drivers killed in a road crash in France: a spectacular increase for cannabis, cocaine and amphetamines.
Topics: Accidents, Traffic; Adolescent; Adult; Amphetamines; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Dronabinol; Female; Forensic Medicine; France; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Male; Morphine; Narcotics; Substance Abuse Detection; Substance-Related Disorders | 2006 |
Effects of prenatal cocaine, morphine, or both on postnatal opioid (mu) receptor development.
Topics: Aging; Animals; Brain; Cocaine; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sulpiride | 2006 |
Differential effects of morphine- and cocaine-induced nNOS immunoreactivity in the dentate gyrus of hippocampus of mice lacking mu-opioid receptors.
Topics: Animals; Cocaine; Dentate Gyrus; Dopamine Uptake Inhibitors; Immunohistochemistry; Mice; Mice, Knockout; Morphine; Narcotics; Nitric Oxide Synthase Type I; Receptors, Opioid, mu | 2006 |
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines | 2006 |
Surface-activated chemical ionization ion trap mass spectrometry in the analysis of drugs in dilute urine samples. Part II: analysis of morphine and other street drugs.
Topics: Cocaine; Codeine; Humans; Illicit Drugs; Mass Spectrometry; Morphine; Morphine Derivatives; Sensitivity and Specificity | 2005 |
Ethanol-induced conditioned place preference, but not aversion, is blocked by treatment with D -penicillamine, an inactivation agent for acetaldehyde.
Topics: Acetaldehyde; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Antagonism; Ethanol; Male; Mice; Morphine; Motor Activity; Penicillamine | 2006 |
Region-specific effects of brain corticotropin-releasing factor receptor type 1 blockade on footshock-stress- or drug-priming-induced reinstatement of morphine conditioned place preference in rats.
Topics: Amygdala; Animals; Behavior, Animal; Brain; Central Nervous System Agents; Cocaine; Conditioning, Operant; Extinction, Psychological; Heroin; Injections, Intraventricular; Learning; Male; Morphine; Nucleus Accumbens; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Septal Nuclei; Stress, Psychological | 2006 |
Application of pericardial fluid to the analysis of morphine (heroin) and cocaine in forensic toxicology.
Topics: Cocaine; Codeine; Dopamine Uptake Inhibitors; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Morphine; Narcotics; Pericardium; Postmortem Changes; Substance Abuse Detection | 2006 |
Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference.
Topics: Aminoacetonitrile; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Protease Inhibitors; Protein Biosynthesis | 2006 |
Alcohol-, nicotine-, and cocaine-evoked release of morphine from invertebrate ganglia: model system for screening drugs of abuse.
Topics: Animals; Cocaine; Drug Evaluation, Preclinical; Ethanol; Ganglia, Invertebrate; Illicit Drugs; In Vitro Techniques; Morphine; Mytilus edulis; Nephropidae; Nicotine | 2006 |
Prenatal cocaine alters later responses to morphine in adult male mice.
Topics: Aggression; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cocaine; Conditioning, Operant; Exploratory Behavior; Female; Interpersonal Relations; Male; Mice; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reward | 2006 |
Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Benzazepines; Benzodiazepines; Cocaine; Conditioning, Psychological; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Receptors, Dopamine D1; Sulpiride | 2006 |
Renewal effect: context-dependent extinction of a cocaine- and a morphine-induced conditioned floor preference.
Topics: Animals; Association Learning; Choice Behavior; Cocaine; Conditioning, Classical; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Injections, Intraperitoneal; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Social Environment | 2006 |
Effect of morphine on locomotor activity and striatal monoamine metabolism in nicotine-withdrawn mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Biogenic Monoamines; Central Nervous System Stimulants; Cocaine; Dopamine; Drug Interactions; Male; Mice; Morphine; Motor Activity; Narcotics; Neostriatum; Nicotine; Norepinephrine; Nucleus Accumbens; Serotonin; Substance Withdrawal Syndrome | 2006 |
Noradrenaline is necessary for the hedonic properties of addictive drugs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Appetitive Behavior; Benzazepines; Biphenyl Compounds; Bupropion; Carbidopa; Cocaine; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Droxidopa; Female; Genotype; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Reward; Substance-Related Disorders | 2006 |
Characterization of cannabinoid agonists and apparent pA2 analysis of cannabinoid antagonists in rhesus monkeys discriminating Delta9-tetrahydrocannabinol.
Topics: Analgesics, Opioid; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; Animals; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Cocaine; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Female; Hallucinogens; Ketamine; Macaca mulatta; Male; Midazolam; Morphine; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2006 |
Alcohol-, nicotine-, and cocaine-evoked release of morphine from human white blood cells: substances of abuse actions converge on endogenous morphine release.
Topics: Alcohols; Cocaine; Dose-Response Relationship, Drug; Humans; Iodine Radioisotopes; Leukocytes; Leukocytes, Mononuclear; Morphine; Neutrophils; Nicotine; Radioimmunoassay; Substance-Related Disorders | 2006 |
Maternal deprivation specifically enhances vulnerability to opiate dependence.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain; Central Nervous System Depressants; Cocaine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Ethanol; Female; Male; Maternal Deprivation; Morphine; Pregnancy; Rats; Rats, Long-Evans; Self Administration; Substance-Related Disorders | 2006 |
Behavioral effects of morphine and cocaine in M1 muscarinic acetylcholine receptor-deficient mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Muscarinic Antagonists; Pain Measurement; Pain Threshold; Pirenzepine; Receptor, Muscarinic M1; Reward | 2007 |
Four years' experience in external proficiency testing programs for hair testing of drugs of abuse in Italy (HAIRVEQ) and comparison with the Society of Hair Testing program in 2005.
Topics: 3,4-Methylenedioxyamphetamine; Clinical Laboratory Techniques; Cocaine; Codeine; False Negative Reactions; False Positive Reactions; Forensic Medicine; Hair; Humans; Italy; Laboratories; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Opioid Peptides; Program Evaluation; Reproducibility of Results; Spain; Statistical Distributions; Substance Abuse Detection; Time Factors | 2007 |
History of cocaine self-administration alters morphine reinforcement in the rat.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Infusions, Intravenous; Injections, Intraperitoneal; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2007 |
Clonidine attenuates morphine withdrawal and subsequent drug sensitization in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Clonidine; Cocaine; Macaca mulatta; Male; Morphine; Morphine Dependence; Narcotics; Substance Withdrawal Syndrome | 2007 |
Foster mother care but not prenatal morphine exposure enhances cocaine self-administration in young adult male and female rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Estrous Cycle; Female; Male; Maternal Behavior; Morphine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Sex Factors; Sodium Chloride; Sucrose | 2007 |
Broad-spectrum toxicological analysis of hair based on capillary zone electrophoresis-time-of-flight mass spectrometry.
Topics: Amphetamine; Cocaine; Electrophoresis, Capillary; Ephedrine; Forensic Medicine; Hair; Heroin; Humans; Illicit Drugs; Morphine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance Abuse Detection | 2007 |
Spectroscopic and electrochemical studies of cocaine-opioid interactions.
Topics: Analgesics, Opioid; Binding Sites; Cocaine; Drug Interactions; Electrochemistry; Morphine; Quantum Theory; Solutions; Spectrum Analysis | 2007 |
Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals.
Topics: Chromatography, Liquid; Cities; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Ireland; Morphine; Pharmaceutical Preparations; Pyrrolidines; Residence Characteristics; Rivers; Solid Phase Extraction; Substance-Related Disorders; Tandem Mass Spectrometry; Temazepam; Waste Disposal, Fluid; Water Pollutants, Chemical | 2007 |
Development and validation of the Cozart DDS oral fluid collection device.
Topics: Amphetamines; Automobile Driving; Cocaine; Dopamine Uptake Inhibitors; Dronabinol; Forensic Toxicology; Hallucinogens; Humans; Hypnotics and Sedatives; Methadone; Morphine; Narcotics; Saliva; Substance Abuse Detection; Temazepam | 2007 |
Distribution of drugs of abuse within specific regions of the human brain.
Topics: Adolescent; Adult; Aged; Cerebellum; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Medulla Oblongata; Middle Aged; Morphine; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Tissue Distribution | 2007 |
Conditioned drug reward enhances subsequent spatial learning and memory in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Male; Maze Learning; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior | 2007 |
Differences in dopamine responsiveness to drugs of abuse in the nucleus accumbens shell and core of Lewis and Fischer 344 rats.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Male; Microdialysis; Morphine; Motor Activity; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Species Specificity; Stereotyped Behavior; Substance-Related Disorders | 2007 |
Overexpression of plasminogen activators in the nucleus accumbens enhances cocaine-, amphetamine- and morphine-induced reward and behavioral sensitization.
Topics: Amphetamine; Animals; Base Sequence; Behavior, Animal; Cocaine; DNA Primers; Doxycycline; Lentivirus; Male; Molecular Sequence Data; Morphine; Nucleus Accumbens; Plasminogen Activators; Polymerase Chain Reaction; Rats; Rats, Wistar; Reward; RNA, Small Interfering; RNA, Viral; Tissue Plasminogen Activator; Viral Proteins | 2008 |
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection | 2007 |
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice.
Topics: Analgesia; Animals; Behavior, Addictive; Carrier Proteins; Cocaine; Crosses, Genetic; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Heterozygote; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Locomotion; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Nucleus Accumbens | 2007 |
Drugs of abuse specifically sensitize noradrenergic and serotonergic neurons via a non-dopaminergic mechanism.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Administration Schedule; Drug Interactions; Ethanol; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Norepinephrine; p-Chloroamphetamine; Serotonin; Serotonin Agents; Substance-Related Disorders | 2008 |
Specific blockade of morphine- and cocaine-induced reinforcing effects in conditioned place preference by nitrous oxide in mice.
Topics: Analgesics, Opioid; Animals; Anxiety; Cocaine; Conditioning, Operant; Food Preferences; Male; Memory; Mice; Morphine; Motor Activity; Nitrous Oxide; Recognition, Psychology; Reinforcement, Psychology; Reward; Swimming | 2007 |
Illicit drugs, a novel group of environmental contaminants.
Topics: Amphetamines; Cocaine; Dronabinol; Environmental Monitoring; Fresh Water; Illicit Drugs; Italy; Morphine; Switzerland; United Kingdom; Water Pollutants, Chemical | 2008 |
Complicated interaction between psychostimulants and morphine in expression of phenotype of behavior in the dopaminergic system of BALB/c mice.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Limbic System; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Neurons; Substantia Nigra; Time Factors | 2007 |
Involvement of brain catalase activity in the acquisition of ethanol-induced conditioned place preference.
Topics: Albinism; Animals; Behavior, Animal; Brain; Catalase; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Ethanol; Extinction, Psychological; Male; Morphine; Narcotics; Rats; Reinforcement, Psychology | 2008 |
Effect of adolescent exposure to MDMA and cocaine on acquisition and reinstatement of morphine-induce CPP.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Male; Mice; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Reinforcement, Psychology | 2008 |
The role of beta-endorphin in the acute motor stimulatory and rewarding actions of cocaine in mice.
Topics: Animals; Association Learning; beta-Endorphin; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Crosses, Genetic; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Genetic Carrier Screening; Genotype; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Morphine; Motivation; Motor Activity; Pro-Opiomelanocortin; Reward; Social Environment | 2008 |
Glucocorticoids involvement in the control of CNS excitability.
Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Dactinomycin; Dexamethasone; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Male; Morphine; Motor Activity; Serotonin | 2007 |
Distinct patterns of DeltaFosB induction in brain by drugs of abuse.
Topics: Animals; Brain Chemistry; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Dronabinol; Ethanol; Hallucinogens; Illicit Drugs; Immunohistochemistry; Male; Morphine; Narcotics; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Self Administration | 2008 |
Nucleus accumbens core acetylcholine is preferentially activated during acquisition of drug- vs food-reinforced behavior.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cocaine; Conditioning, Psychological; Disease Models, Animal; Dopamine; Feeding Behavior; Learning; Male; Morphine; Nucleus Accumbens; Piperidines; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Reinforcement, Psychology; Remifentanil; Substance-Related Disorders; Synaptic Transmission | 2008 |
Inhibitory effects of opioids on compound action potentials in frog sciatic nerves and their chemical structures.
Topics: Action Potentials; Analgesics, Opioid; Animals; Calcium Channels; Cocaine; Codeine; Ethylmorphine; Female; Male; Morphine; Naloxone; Potassium Channels, Voltage-Gated; Ranidae; Receptors, Opioid; Sciatic Nerve; Structure-Activity Relationship; Tetrodotoxin | 2008 |
Nails of newborns in monitoring drug exposure during pregnancy.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine; Nails; Narcotics; Nicotine; Nicotinic Agonists; Pregnancy; Smoking | 2008 |
Antidepressants alleviate the impact of reinforcer downshift.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central Nervous System Stimulants; Chlordiazepoxide; Citalopram; Cocaine; Conditioning, Operant; Desipramine; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors | 2009 |
Gustatory insular cortex lesions disrupt drug-induced, but not lithium chloride-induced, suppression of conditioned stimulus intake.
Topics: Adjuvants, Immunologic; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Brain Injuries; Cerebral Cortex; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Food Preferences; Inhibition, Psychological; Lithium Chloride; Male; Morphine; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley | 2008 |
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Body Fluids; Calibration; Chromatography, High Pressure Liquid; Cocaine; Dronabinol; Humans; Illicit Drugs; Ketamine; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2009 |
Morphine, cocaine, and 19th century cancer care.
Topics: Cocaine; Drug Combinations; History, 19th Century; History, 20th Century; Humans; Morphine; Neoplasms | 2008 |
Genetic influences on drug-induced psychomotor activation in mice.
Topics: Animals; Binding, Competitive; Chromosome Mapping; Cocaine; DNA Mutational Analysis; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Resistance; Ethanol; Female; Genetic Predisposition to Disease; Genetic Testing; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Motor Activity; Presynaptic Terminals; Psychomotor Agitation; Species Specificity; Substance-Related Disorders; Synaptosomes | 2008 |
Current trends in drug abuse associated fatalities - Jordan, 2000-2004.
Topics: Accidents; Accidents, Traffic; Adult; Benzodiazepines; Cause of Death; Central Nervous System Depressants; Cocaine; Death, Sudden; Drug Overdose; Ethanol; Female; Forensic Toxicology; Heroin; Humans; Jordan; Male; Middle Aged; Morphine; Narcotics; Retrospective Studies; Substance-Related Disorders; Suicide | 2009 |
Simultaneous determination of morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in hair by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Hair; Humans; Morphine; Morphine Derivatives; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2009 |
GABA(A) receptors mediate the opposing roles of dopamine and the tegmental pedunculopontine nucleus in the motivational effects of ethanol.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bicuculline; Cocaine; Conditioning, Operant; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Female; Functional Laterality; GABA Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motivation; Narcotics; Pedunculopontine Tegmental Nucleus; Receptors, Dopamine D2; Receptors, GABA-A; Reinforcement, Psychology; Substance Withdrawal Syndrome; Time Factors | 2009 |
Cocaine and heroin in waste water plants: a 1-year study in the city of Florence, Italy.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Illicit Drugs; Italy; Morphine; Narcotics; Seasons; Substance-Related Disorders; Waste Disposal, Fluid; Water | 2009 |
Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Hair; Humans; Illicit Drugs; Microwaves; Morphine; Morphine Derivatives; Narcotics | 2009 |
Examination of reinforcement magnitude on the pharmacological disruption of fixed-ratio performance.
Topics: Animals; Chlordiazepoxide; Clonidine; Cocaine; Columbidae; Conditioning, Operant; Ethanol; Extinction, Psychological; Food Deprivation; Haloperidol; Morphine; Reinforcement Schedule; Reinforcement, Psychology; Time Factors | 2009 |
Simultaneous quantification of methadone, cocaine, opiates, and metabolites in human placenta by liquid chromatography-mass spectrometry.
Topics: Adult; Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Methadone; Morphine; Morphine Derivatives; Placenta; Pregnancy; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Young Adult | 2009 |
The absence of a functional peroxisome proliferator-activated receptor-alpha gene in mice enhances motor sensitizing effects of morphine, but not cocaine.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Narcotics; PPAR alpha; Pyrimidines; Time Factors | 2009 |
[Obligatory documentation for narcotic drugs over the course of time : the morphine and cocaine book for physicians according to the 1930 parliamentary law gazette].
Topics: Analgesics, Opioid; Cocaine; Documentation; Drug and Narcotic Control; Drug Prescriptions; Germany; History, 20th Century; Humans; Morphine; Opium | 2009 |
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
Topics: Analysis of Variance; Animals; Anisomycin; Cocaine; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Green Fluorescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Motor Activity; Narcotics; Point Mutation; Protein Synthesis Inhibitors; Raclopride; Receptors, Dopamine D1; Substance-Related Disorders; Threonine; Time Factors | 2010 |
Perinatal undernutrition facilitates morphine sensitization and cross-sensitization to cocaine in adult rats: a behavioral and neurochemical study.
Topics: Aging; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Locomotion; Male; Malnutrition; Morphine; Narcotics; Nucleus Accumbens; Pregnancy; Prenatal Exposure Delayed Effects; Putamen; Rats; Rats, Wistar | 2010 |
Evaluation of on-site oral fluid screening using Drugwipe-5(+), RapidSTAT and Drug Test 5000 for the detection of drugs of abuse in drivers.
Topics: Amphetamines; Automobile Driving; Cocaine; Dronabinol; Forensic Toxicology; Humans; Morphine; Narcotics; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 2010 |
Tunable detection sensitivity of opiates in urine via a label-free porous silicon competitive inhibition immunosensor.
Topics: Antibodies; Binding, Competitive; Biosensing Techniques; Cocaine; Lab-On-A-Chip Devices; Morphine; Morphine Derivatives; Narcotics; Oxycodone; Porosity; Silicon; Substance Abuse Detection | 2010 |
Orexin mediates morphine place preference, but not morphine-induced hyperactivity or sensitization.
Topics: Animals; Benzoxazoles; Central Nervous System Agents; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Mutation; Naphthyridines; Narcotics; Neuropeptides; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Space Perception; Time Factors; Urea | 2010 |
Gas chromatography-mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation.
Topics: Abortion, Induced; Amphetamines; Cocaine; Cotinine; Dronabinol; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Maternal Exposure; Maternal-Fetal Exchange; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nicotine; Placenta; Pregnancy; Pregnancy Trimester, First; Specimen Handling; Substance Abuse Detection | 2010 |
Upregulation of L-type Ca(v)1 channels in the development of psychological dependence.
Topics: Animals; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cocaine; Disease Models, Animal; Frontal Lobe; Limbic System; Male; Methamphetamine; Mice; Morphine; Nifedipine; Substance-Related Disorders; Up-Regulation | 2010 |
CEC-ESI ion trap MS of multiple drugs of abuse.
Topics: Amphetamines; Capillary Electrochromatography; Cocaine; Humans; Illicit Drugs; Linear Models; Mass Spectrometry; Morphine; Reproducibility of Results; Sensitivity and Specificity | 2010 |
Roche DAT immunoassay: sensitivity and specificity testing for amphetamines, cocaine, and opiates in oral fluid.
Topics: Amphetamines; Cocaine; Codeine; Cross Reactions; False Negative Reactions; False Positive Reactions; Humans; Immunoassay; Methamphetamine; Morphine; Opiate Alkaloids; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Tandem Mass Spectrometry | 2010 |
Comparative toxicology of intentional and accidental heroin overdose.
Topics: Accidents; Adult; Body Mass Index; Central Nervous System Depressants; Cocaine; Drug Overdose; Ethanol; Female; Forensic Toxicology; Heroin; Humans; Liver; Lymphocytes; Male; Methadone; Morphine; Narcotics; Sex Distribution; Suicide | 2010 |
Concentrations of opiates and psychotropic agents in polydrug overdoses: a surprising correlation between morphine and antidepressants.
Topics: Accidents; Adolescent; Adult; Aged; Antidepressive Agents; Benzodiazepines; Central Nervous System Depressants; Cocaine; Drug Overdose; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Illicit Drugs; Male; Middle Aged; Morphine; Narcotics; Psychotropic Drugs | 2010 |
Effects of fatty acid amide hydrolase inhibition on neuronal responses to nicotine, cocaine and morphine in the nucleus accumbens shell and ventral tegmental area: involvement of PPAR-alpha nuclear receptors.
Topics: Amidohydrolases; Animals; Benzamides; Carbamates; Cocaine; Dopamine; Evoked Potentials; Male; Morphine; Neurons; Nicotine; Nucleus Accumbens; PPAR alpha; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Reward; Ventral Tegmental Area | 2010 |
Glucocorticoid receptors in dopaminoceptive neurons, key for cocaine, are dispensable for molecular and behavioral morphine responses.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Depressants; Cocaine; Dopamine; Gene Silencing; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Morphine; Mutation; Neurons; Receptors, Glucocorticoid; Reinforcement, Psychology; Substance-Related Disorders | 2010 |
Conditioned saccharin avoidance and sensitization to drugs of abuse.
Topics: Amphetamine; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Illicit Drugs; Male; Morphine; Nicotine; Rats; Rats, Sprague-Dawley; Saccharin | 2010 |
Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area.
Topics: Analgesics, Opioid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Illicit Drugs; Long-Term Potentiation; Morphine; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Stress, Physiological; Synapses; Ventral Tegmental Area | 2010 |
Reinforcer-dependent enhancement of operant responding in opioid-withdrawn rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement Schedule; Remifentanil; Self Administration; Substance Withdrawal Syndrome | 2010 |
Cocaine- and morphine-induced synaptic plasticity in the nucleus accumbens.
Topics: Animals; Cocaine; Female; Morphine; Neuronal Plasticity; Nucleus Accumbens; Random Allocation; Rats; Rats, Sprague-Dawley; Synapses | 2011 |
Matrix solid-phase dispersion on column clean-up/pre-concentration as a novel approach for fast isolation of abuse drugs from human hair.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hydrochloric Acid; Illicit Drugs; Methanol; Morphine; Multivariate Analysis; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction | 2010 |
Percentile-based spread: a more accurate way to compare crystallographic models.
Topics: Antibodies; Cocaine; Crystallography, X-Ray; Models, Molecular; Morphine; Protein Structure, Tertiary | 2010 |
A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-triple quadrupole mass spectrometer.
Topics: Amphetamines; Calibration; Chromatography, Liquid; Cocaine; Humans; Linear Models; Mass Spectrometry; Methadone; Morphine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection | 2010 |
Multiplexed detection of metabolites of narcotic drugs from a single latent fingermark.
Topics: Biological Assay; Cocaine; Dermatoglyphics; Humans; Immunoassay; Immunoconjugates; Magnetics; Morphine; Narcotics; Substance Abuse Detection; Time Factors | 2010 |
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells.
Topics: Action Potentials; Animals; Animals, Newborn; Behavior, Animal; Benzoxazines; Cocaine; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Illicit Drugs; In Vitro Techniques; Male; Mecamylamine; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Neural Inhibition; Neural Pathways; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Time Factors; Ventral Tegmental Area | 2011 |
Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Male; Morphine; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Thiazoles | 2011 |
Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Psychological; Galanin; Male; Mice; Mice, 129 Strain; Mice, Congenic; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Morphine; Nicotine; Nucleus Accumbens; Phosphorylation; Reward; Signal Transduction; Synaptic Transmission | 2011 |
On-line solid-phase extraction coupled to hydrophilic interaction chromatography-mass spectrometry for the determination of polar drugs.
Topics: Chromatography, Liquid; Cocaine; Hydrophobic and Hydrophilic Interactions; Illicit Drugs; Linear Models; Mass Spectrometry; Morphine; Pharmaceutical Preparations; Reproducibility of Results; Rivers; Sensitivity and Specificity; Solid Phase Extraction; Water Pollutants, Chemical | 2011 |
Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation.
Topics: Animals; Cocaine; Dependovirus; Dopamine; Electrophysiology; Glutamine; Mice; Mice, Inbred C57BL; Morphine; Neurons; Nicotine; Receptors, AMPA; Synapses; Ventral Tegmental Area | 2010 |
Opioid facilitation of rewarding electrical brain stimulation is suppressed in rats with neuropathic pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Heroin; Hyperalgesia; Ligation; Male; Morphine; Neuralgia; Pain Measurement; Pressure; Rats; Rats, Inbred F344; Reward; Self Stimulation; Spinal Nerves; Ventral Tegmental Area | 2011 |
Dorsal as well as ventral striatal lesions affect levels of intravenous cocaine and morphine self-administration in rats.
Topics: Animals; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Male; Morphine; Narcotics; Neostriatum; Nucleus Accumbens; Rats; Rats, Long-Evans; Reward; Self Administration; Substance-Related Disorders | 2011 |
[Involvement of brain neurotrophic factors in the pathogenesis of chemical dependences].
Topics: Alcoholism; Animals; Brain; Cocaine; Cocaine-Related Disorders; Ethanol; Humans; Methamphetamine; Mice; Morphine; Morphine Dependence; Nerve Growth Factors | 2010 |
Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients.
Topics: Cocaine; Cocaine-Related Disorders; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Saliva; Self Report; Substance Abuse Detection | 2012 |
Trends and pattern of drug abuse deaths in Maryland teenagers.
Topics: Adolescent; Age Distribution; Black People; Butanes; Cause of Death; Chlorofluorocarbons, Methane; Cocaine; Female; Forensic Pathology; Forensic Toxicology; Hepatitis B Antibodies; Heroin; HIV Antibodies; Humans; Male; Maryland; Methadone; Morphine; Myocarditis; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nitrous Oxide; Pneumonia; Propane; Retrospective Studies; Sex Distribution; Substance-Related Disorders; White People | 2011 |
Illicit drugs in alternative biological specimens: a case report.
Topics: Adult; Cocaine; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Kidney; Liver; Male; Morphine; Narcotics; Substance-Related Disorders; Vitreous Body | 2011 |
Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocytosis; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Oligopeptides; Organophosphonates; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Reward; Substance Withdrawal Syndrome; Time Factors; Valine | 2011 |
Effects of daily morphine administration and deprivation on choice and demand for remifentanil and cocaine in rhesus monkeys.
Topics: Analgesics, Opioid; Animals; Choice Behavior; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Infusions, Intravenous; Macaca mulatta; Male; Morphine; Morphine Dependence; Motivation; Piperidines; Remifentanil; Substance Withdrawal Syndrome | 2011 |
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Buprenorphine; Chromatography, Liquid; Cocaine; Codeine; Dronabinol; Ethylmorphine; Humans; Illicit Drugs; Methadone; Morphine; Oxycodone; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2011 |
Drug overdose deaths--Florida, 2003-2009.
Topics: Alprazolam; Cause of Death; Cocaine; Drug Overdose; Florida; Humans; Illicit Drugs; Methadone; Morphine; Mortality; Oxycodone; Prescription Drugs | 2011 |
Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures.
Topics: Animals; Cocaine; Coculture Techniques; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Female; Immunohistochemistry; Limbic System; Male; Methamphetamine; Morphine; Neurons; Propidium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse.
Topics: Action Potentials; Analysis of Variance; Animals; Benzoxazines; Cannabinoids; Cocaine; Dopaminergic Neurons; Electric Stimulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Morphine; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Physical Stimulation; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Tegmentum Mesencephali; Time Factors; Ventral Tegmental Area | 2012 |
Intracranial self-stimulation of the paraventricular nucleus of the hypothalamus: increased faciliation by morphine compared to cocaine.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Cocaine; Data Interpretation, Statistical; Electric Stimulation; Electrodes, Implanted; Hyperalgesia; Ligation; Male; Morphine; Pain Measurement; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred F344; Self Stimulation; Spinal Nerves | 2012 |
The dual orexin receptor antagonist almorexant, alone and in combination with morphine, cocaine and amphetamine, on conditioned place preference and locomotor sensitization in the rat.
Topics: Acetamides; Amphetamine; Anesthetics; Animals; Cocaine; Conditioning, Operant; Dopamine Agents; Drug Interactions; Dual Oxidases; Flavoproteins; Isoquinolines; Locomotion; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward | 2013 |
The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice.
Topics: Animals; Behavior, Animal; beta-Endorphin; Cocaine; Conditioning, Operant; Male; Mice; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Reward | 2012 |
Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Drug Contamination; Forensic Pathology; Heroin; Humans; Illicit Drugs; Morphine; Morphine Derivatives; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Xylazine | 2012 |
α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission.
Topics: Animals; Cocaine; Dopamine; Infusions, Intraventricular; Limbic System; Male; Morphine; Motor Activity; Nucleus Accumbens; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Synaptic Transmission | 2012 |
Bilateral lesions of the thalamic trigeminal orosensory area dissociate natural from drug reward in contrast paradigms.
Topics: Analysis of Variance; Animals; Antimanic Agents; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Conditioning, Operant; Dopamine Uptake Inhibitors; Eating; Excitatory Amino Acid Agonists; Food Preferences; Ibotenic Acid; Lithium Chloride; Male; Morphine; Rats; Rats, Sprague-Dawley; Reaction Time; Reward; Saccharin; Taste; Thalamus | 2012 |
Simultaneous quantification of morphine and cocaine in hair samples from drug addicts by GC-EI/MS.
Topics: Cocaine; Drug Users; Gas Chromatography-Mass Spectrometry; Hair; Humans; Linear Models; Male; Morphine; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection | 2012 |
Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Cannabidiol; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes, Implanted; Male; Medial Forebrain Bundle; Microinjections; Morphine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reward; Self Stimulation; Sensory Thresholds; Serotonin Antagonists | 2013 |
Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the H₂O₂ scavenger alpha lipoic acid.
Topics: Acetaldehyde; Animals; Antioxidants; Brain; Cocaine; Conditioning, Classical; Ethanol; Hydrogen Peroxide; Mice; Morphine; Reward; Thioctic Acid | 2013 |
Inhibitory effects of SA4503 on the rewarding effects of abused drugs.
Topics: Animals; Cocaine; Conditioning, Operant; Conditioning, Psychological; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibition, Psychological; Male; Methamphetamine; Morphine; Narcotics; Nootropic Agents; Pentazocine; Piperazines; Psychomotor Performance; Rats, Inbred F344; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2014 |
Does prenatal methamphetamine exposure induce cross-sensitization to cocaine and morphine in adult male rats?
Topics: Animals; Behavior, Animal; Cocaine; Drug-Seeking Behavior; Female; Male; Methamphetamine; Morphine; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2012 |
Evaluation of pre-analysis loss of dependent drugs in wastewater: stability and binding assessments.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Codeine; Cotinine; Drug Stability; Illicit Drugs; Liquid-Liquid Extraction; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2013 |
Behavioral and antinociceptive effects of different psychostimulant drugs in prenatally methamphetamine-exposed rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Female; Male; Methamphetamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2012 |
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste | 2013 |
A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm.
Topics: Animals; Behavior, Animal; Buprenorphine; Cocaine; Conditioning, Psychological; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward | 2014 |
The selective D₃ receptor antagonist SB-277011A attenuates morphine-triggered reactivation of expression of cocaine-induced conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Classical; Cues; Dopamine Antagonists; Drug-Seeking Behavior; Male; Morphine; Motivation; Nitriles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Tetrahydroisoquinolines | 2013 |
Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphine in brain and liver mitochondria.
Topics: Animals; Brain; Cell Respiration; Cocaine; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, Liver; Morphine; Rats; Rats, Wistar | 2013 |
Juvenile ethanol exposure increases rewarding properties of cocaine and morphine in adult DBA/2J mice.
Topics: Age Factors; Analgesics; Animals; Animals, Newborn; Brain; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Ethanol; Extracellular Signal-Regulated MAP Kinases; Locomotion; Male; Mice; Mice, Inbred DBA; Morphine; Reward | 2013 |
Acute effects of cocaine, morphine and their combination on bioenergetic function and susceptibility to oxidative stress of rat liver mitochondria.
Topics: Animals; Cocaine; Drug Combinations; Energy Metabolism; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Morphine; Oxidative Stress; Rats; Rats, Wistar; Time Factors | 2013 |
A field test of substance use screening devices as part of routine drunk-driving spot detection operating procedures in South Africa.
Topics: Adolescent; Adult; Alcohol Drinking; Alcoholic Intoxication; Amphetamine; Automobile Driving; Breath Tests; Chromatography, Liquid; Cocaine; Dronabinol; Ethanol; Female; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Male; Mass Spectrometry; Methamphetamine; Middle Aged; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Pilot Projects; Saliva; South Africa; Substance Abuse Detection; Young Adult | 2013 |
Assessing addiction vulnerability with different rat strains and place preference procedures: the role of the cocaine and amphetamine-regulated transcript.
Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Drug-Seeking Behavior; Gene Expression Regulation; Male; Morphine; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; RNA, Messenger; Species Specificity | 2013 |
Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
Topics: Animals; Cocaine; Conditioning, Operant; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Metabolic Networks and Pathways; Metabolome; Methamphetamine; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Substance-Related Disorders | 2014 |
Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Cues; Drug-Seeking Behavior; Ethanol; Male; Maze Learning; Memory; Morphine; Motor Activity; Protein Kinase Inhibitors; Rats; Reward; Sirolimus | 2014 |
Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action.
Topics: Animals; Chromatin Immunoprecipitation; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Immunoblotting; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Narcotics; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Reward; Signal Transduction; Sirtuin 1; Sirtuin 2 | 2013 |
Simultaneous determination of cocaine and opiates in dried blood spots by electrospray ionization tandem mass spectrometry.
Topics: Analgesics, Opioid; Cocaine; Codeine; Dried Blood Spot Testing; Humans; Limit of Detection; Methanol; Morphine; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Tandem Mass Spectrometry | 2013 |
Conditioned rewarding effects of morphine and methadone in mice pre-exposed to cocaine.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Mice; Mice, Inbred C57BL; Morphine; Motivation; Reward; Time Factors | 2013 |
The involvement of accumbal glycine receptors in the dopamine-elevating effects of addictive drugs.
Topics: Animals; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ethanol; Glycine Agents; Hallucinogens; Illicit Drugs; Male; Microdialysis; Microelectrodes; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats, Wistar; Receptors, Glycine; Strychnine; Synaptic Transmission | 2014 |
Comprehensive automation of the solid phase extraction gas chromatographic mass spectrometric analysis (SPE-GC/MS) of opioids, cocaine, and metabolites from serum and other matrices.
Topics: Acetamides; Analgesics, Opioid; Automation; Cocaine; Codeine; Flunitrazepam; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Robotics; Solid Phase Extraction; Substance Abuse Detection; Trimethylsilyl Compounds | 2014 |
A study on photodegradation of methadone, EDDP, and other drugs of abuse in hair exposed to controlled UVB radiation.
Topics: Analgesics, Opioid; Cocaine; Hair; Humans; Methadone; Morphine; Morphine Derivatives; Photolysis; Pyrrolidines; Substance Abuse Detection; Ultraviolet Rays | 2014 |
Simultaneous determination of drugs of abuse and their main metabolites using pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, Liquid; Cocaine; Codeine; Methadone; Morphine; Reproducibility of Results; Sewage; Solvents; Spectrometry, Mass, Electrospray Ionization; Substance-Related Disorders; Tandem Mass Spectrometry; Temperature; Water Pollutants, Chemical | 2014 |
eIF2α dephosphorylation in basolateral amygdala mediates reconsolidation of drug memory.
Topics: Amygdala; Animals; Cocaine; Cues; Drug-Seeking Behavior; Eukaryotic Initiation Factor-2; Heroin; Male; Memory; Morphine; Phosphorylation; Rats; Rats, Sprague-Dawley; Self Administration | 2014 |
Analysis of drugs of abuse in human plasma by dispersive liquid-liquid microextraction and high-performance liquid chromatography.
Topics: Analytic Sample Preparation Methods; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cocaine; Humans; Hydrogen-Ion Concentration; Illicit Drugs; Limit of Detection; Liquid Phase Microextraction; Methadone; Morphine; Morphine Derivatives; Opiate Substitution Treatment; Photometry; Reproducibility of Results; Solubility; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substance-Related Disorders; Ultrasonics | 2015 |
Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area.
Topics: Animals; Cocaine; Conditioning, Classical; Enzyme Induction; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Nerve Tissue Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-myc; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Up-Regulation; Ventral Tegmental Area | 2015 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Acute morphine and cocaine related death after trimethoprim-adultered cocaine abuse.
Topics: Cocaine; Cocaine-Related Disorders; Cytochrome P-450 CYP2C8 Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Morphine; Trimethoprim | 2014 |
AMN082, a metabotropic glutamate receptor 7 allosteric agonist, attenuates locomotor sensitization and cross-sensitization induced by cocaine and morphine in mice.
Topics: Allosteric Regulation; Animals; Benzhydryl Compounds; Central Nervous System Sensitization; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Locomotion; Male; Mice; Morphine; Pyridones; Receptors, Metabotropic Glutamate | 2015 |
Effects of rimonabant on the development of single dose-induced behavioral sensitization to ethanol, morphine and cocaine in mice.
Topics: Akathisia, Drug-Induced; Animals; Animals, Outbred Strains; Anxiety; Cannabinoid Receptor Antagonists; Central Nervous System Depressants; Cocaine; Depression; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Morphine; Motor Activity; Narcotics; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance-Related Disorders | 2015 |
Temporal regulation of peripheral BDNF levels during cocaine and morphine withdrawal: comparison with a natural reward.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Sprague-Dawley; Reward; Substance Withdrawal Syndrome | 2014 |
Indirect competitive assays on DVD for direct multiplex detection of drugs of abuse in oral fluids.
Topics: Cocaine; Dopamine Uptake Inhibitors; Equipment Design; Humans; Illicit Drugs; Immunoassay; Limit of Detection; Microfluidic Analytical Techniques; Morphine; Narcotics; Saliva; Substance Abuse Detection | 2015 |
Application of drug testing using exhaled breath for compliance monitoring of drug addicts in treatment.
Topics: Adolescent; Adult; Aged; Amphetamines; Breath Tests; Buprenorphine; Cocaine; Drug Users; Exhalation; Female; Humans; Male; Methadone; Methamphetamine; Middle Aged; Morphine; Morphine Derivatives; Patient Compliance; Substance Abuse Detection; Young Adult | 2015 |
Precise determination of nonlinear function of ion mobility for explosives and drugs at high electric fields for microchip FAIMS.
Topics: Azocines; Cocaine; Electricity; Equipment Design; Explosive Agents; Ions; Mass Spectrometry; Microarray Analysis; Morphine; Nonlinear Dynamics; Triazines; Trinitrotoluene | 2015 |
Discriminative stimulus properties of mitragynine (kratom) in rats.
Topics: Analgesics, Opioid; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids | 2015 |
Effects of prior cocaine versus morphine or heroin self-administration on extinction learning driven by overexpectation versus omission of reward.
Topics: Animals; Cocaine; Conditioning, Classical; Drug-Seeking Behavior; Extinction, Psychological; Heroin; Morphine; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reward; Self Administration | 2015 |
Economical synthesis of 13C-labeled opiates, cocaine derivatives and selected urinary metabolites by derivatization of the natural products.
Topics: Analgesics, Opioid; Biological Products; Carbon-13 Magnetic Resonance Spectroscopy; Cocaine; Codeine; Heroin; Humans; Molecular Structure; Morphine; Morphine Derivatives; Substance Abuse Detection; Urinalysis | 2015 |
Microglia disrupt mesolimbic reward circuitry in chronic pain.
Topics: Animals; Area Under Curve; Chronic Pain; Cocaine; Conditioning, Classical; Disease Models, Animal; Glutamate Decarboxylase; Hyperalgesia; Limbic System; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Minocycline; Morphine; Nerve Net; Nucleus Accumbens; Pain Threshold; Rats; Rats, Sprague-Dawley; Reward; Sciatic Neuropathy; Ventral Tegmental Area | 2015 |
Opioid Overdose Deaths in the City and County of San Francisco: Prevalence, Distribution, and Disparities.
Topics: Adolescent; Adult; Aged; Black or African American; Cocaine; Drug Overdose; Female; Health Status Disparities; Humans; Male; Methadone; Middle Aged; Morphine; Opioid-Related Disorders; Oxycodone; Poverty Areas; Prevalence; San Francisco; Socioeconomic Factors; Young Adult | 2015 |
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; GABAergic Neurons; K Cl- Cotransporters; Male; Mice; Mice, Inbred C57BL; Microglia; Models, Neurological; Morphine; Neuroimmunomodulation; Reward; Substance Withdrawal Syndrome; Symporters; Ventral Thalamic Nuclei | 2016 |
Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dorsal Raphe Nucleus; Extinction, Psychological; Inhibitory Postsynaptic Potentials; Male; Morphine; Patch-Clamp Techniques; Rats, Sprague-Dawley; Receptors, GABA; Self Administration; Serotonergic Neurons; Stress, Psychological; Tissue Culture Techniques; Yohimbine | 2016 |
Early adolescent nicotine exposure affects later-life cocaine reward in mice.
Topics: Aging; Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Eating; Male; Mice; Mice, Inbred ICR; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Reward | 2016 |
Cannabidiol disrupts the reconsolidation of contextual drug-associated memories in Wistar rats.
Topics: Animals; Cannabidiol; Cocaine; Conditioning, Classical; Cues; Disease Models, Animal; Male; Memory; Mental Recall; Morphine; Naltrexone; Rats; Rats, Wistar; Reward | 2017 |
The role of dose and restriction state on morphine-, cocaine-, and LiCl-induced suppression of saccharin intake: A comprehensive analysis.
Topics: Animals; Antimanic Agents; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Eating; Food Deprivation; Food Preferences; Lithium Chloride; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Saccharin; Vasoconstrictor Agents; Water Deprivation | 2016 |
Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol.
Topics: Alcohol Abstinence; Amygdala; Analgesics, Opioid; Animals; Anxiety; Behavior, Animal; Brain; Cannabinoid Receptor Agonists; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Dronabinol; Drug-Seeking Behavior; Emotions; Ethanol; Male; Mice; Morphine; Motivation; Nicotine; Nicotinic Agonists; Proto-Oncogene Proteins c-fos; Social Behavior; Stereotyped Behavior; Substance Withdrawal Syndrome | 2017 |
Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses.
Topics: Animals; Cocaine; Excitatory Postsynaptic Potentials; Male; Morphine; Neuronal Plasticity; Nucleus Accumbens; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 2016 |
Synaptic plasticity: Keeping synapses quiet.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Morphine; Narcotics; Neuronal Plasticity; Neurons; Rats; Synaptic Transmission | 2016 |
Painful progress.
Topics: Anesthesia; Animals; Aspirin; Brain; Cocaine; Complex Regional Pain Syndromes; Dental Caries; Electric Stimulation Therapy; Endorphins; Female; History, 17th Century; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Hyoscyamus; Isoquinolines; Male; Mice; Microglia; Models, Psychological; Morphine; Nerve Block; Neuroimaging; Nitrous Oxide; Nociceptors; Opium; Pain; Pain Management; Receptors, Dopamine; Sex Characteristics; Spinal Puncture; T-Lymphocytes | 2016 |
Rearing environment differentially modulates cocaine self-administration after opioid pretreatment: A behavioral economic analysis.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cocaine; Economics, Behavioral; Environment; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Time Factors | 2016 |
Illicit Fentanyl-Related Fatalities in Florida: Toxicological Findings.
Topics: Adult; Aged; Analgesics, Opioid; Autopsy; Benzodiazepines; Cause of Death; Cocaine; Drug Overdose; Female; Fentanyl; Florida; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Limit of Detection; Male; Middle Aged; Morphine; Morphine Derivatives; Prevalence; Substance Abuse Detection; Young Adult | 2016 |
Optimization of Surface-Enhanced Raman Spectroscopy Conditions for Implementation into a Microfluidic Device for Drug Detection.
Topics: Analgesics, Opioid; Anesthetics, Local; Central Nervous System Stimulants; Cocaine; Gold; Humans; Lab-On-A-Chip Devices; Limit of Detection; Metal Nanoparticles; Methamphetamine; Morphine; Silver; Spectrum Analysis, Raman; Substance Abuse Detection; Surface Properties | 2016 |
Differential effects of aprepitant, a clinically used neurokinin-1 receptor antagonist on the expression of conditioned psychostimulant versus opioid reward.
Topics: Amphetamine; Analgesics, Opioid; Animals; Aprepitant; Association Learning; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Locomotion; Male; Mice; Mice, Inbred C57BL; Morphine; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Reward | 2017 |
Circuit specificity in the inhibitory architecture of the VTA regulates cocaine-induced behavior.
Topics: Animals; Cocaine; Dopaminergic Neurons; Female; Gene Knockdown Techniques; Locomotion; Male; Mice; Morphine; Neural Inhibition; Nucleus Accumbens; Receptor, Adenosine A1; Receptors, GABA-A; Receptors, GABA-B; Reward; Synaptic Transmission; Ventral Tegmental Area | 2017 |
Evaluation of an Automated Reader and Color Interpretation-Based Immunoassays for Multiplexed Drug-of-Abuse Testing in Urine.
Topics: Amphetamine; Automation; Buprenorphine; China; Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Immunoassay; Mass Spectrometry; Methadone; Methamphetamine; Morphine; Sensitivity and Specificity; Substance Abuse Detection | 2017 |
Evaluation of 6 remote First Nations community-based buprenorphine programs in northwestern Ontario: Retrospective study.
Topics: Adult; Benzodiazepines; Buprenorphine; Cocaine; Community Health Services; Counseling; Drug Therapy, Combination; Female; Humans; Indians, North American; Male; Medication Adherence; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Ontario; Opiate Substitution Treatment; Opioid-Related Disorders; Oxycodone; Program Evaluation; Retrospective Studies; Rural Health Services; Substance Abuse Detection; Suicide; Young Adult | 2017 |
Sex differences in the strategies of spatial learning in prenatally-exposed rats treated with various drugs in adulthood.
Topics: Animals; Cocaine; Cognition; Dronabinol; Female; Male; Methamphetamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Psychological Tests; Psychotropic Drugs; Random Allocation; Rats, Wistar; Sex Characteristics; Spatial Learning; Spatial Navigation | 2017 |
Pre-exposure to cocaine or morphine attenuates taste avoidance conditioning in adolescent rats: Drug specificity in the US pre-exposure effect.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Classical; Male; Morphine; Psychotropic Drugs; Rats; Rats, Sprague-Dawley | 2017 |
Mice expressing a "hyper-sensitive" form of the CB1 cannabinoid receptor (CB1) show modestly enhanced alcohol preference and consumption.
Topics: Alcohol Drinking; Animals; Cocaine; Conditioning, Operant; Drug Tolerance; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Morphine; Mutation; Receptor, Cannabinoid, CB1 | 2017 |
Brain lipidomic changes after morphine, cocaine and amphetamine administration - DESI - MS imaging study.
Topics: Amphetamine; Animals; Brain; Cocaine; Lipid Metabolism; Lipids; Male; Morphine; Proteome; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2017 |
Effects of chronic cocaine, morphine and methamphetamine on the mobility, immobility and stereotyped behaviors in crayfish.
Topics: Animals; Astacoidea; Catheters, Indwelling; Cocaine; Dose-Response Relationship, Drug; Male; Methamphetamine; Morphine; Motor Activity; Psychotropic Drugs; Stereotyped Behavior; Video Recording | 2017 |
Perinatal protein deprivation facilitates morphine cross-sensitization to cocaine and enhances ΔFosB expression in adult rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Gene Expression Regulation; Male; Morphine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reward | 2017 |
Drugged Driving in Wisconsin: Oral Fluid Versus Blood.
Topics: Adolescent; Adult; Aged; Amphetamine; Analgesics, Opioid; Automobile Driving; Benzodiazepines; Cocaine; Driving Under the Influence; Ethanol; Female; Forensic Toxicology; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; Morphine; Saliva; Substance Abuse Detection; Wisconsin; Young Adult | 2017 |
Commercial herbal medicines used as African traditional medicines: Ngoma Herbal Tonic Immune Booster interferes with a rapid urine drug screening test.
Topics: Amphetamine; Cocaine; Dronabinol; False Negative Reactions; False Positive Reactions; Humans; Medicine, African Traditional; Methamphetamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Plant Preparations; Substance Abuse Detection | 2017 |
Female rats exhibit less avoidance than male rats of a cocaine-, but not a morphine-paired, saccharin cue.
Topics: Analysis of Variance; Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Corticosterone; Cues; Estrous Cycle; Female; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Sex Characteristics; Taste | 2018 |
Maintenance on naltrexone+amphetamine decreases cocaine-vs.-food choice in male rhesus monkeys.
Topics: Administration, Intravenous; Animals; Choice Behavior; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Food; Macaca mulatta; Male; Morphine; Naltrexone; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration | 2017 |
Proceedings of the 2017 ISEV symposium on "HIV, NeuroHIV, drug abuse, & EVs".
Topics: AIDS Dementia Complex; Anti-HIV Agents; Biomarkers; Cocaine; Drug Carriers; Extracellular Vesicles; Gene Expression; HIV; HIV Envelope Protein gp120; Humans; Methamphetamine; Morphine; Substance-Related Disorders; tat Gene Products, Human Immunodeficiency Virus | 2017 |
Naltrexone maintenance fails to alter amphetamine effects on intracranial self-stimulation in rats.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Deep Brain Stimulation; Dose-Response Relationship, Drug; Male; Medial Forebrain Bundle; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Self Stimulation; Substance-Related Disorders | 2018 |
Effects of drugs of abuse on channelrhodopsin-2 function.
Topics: Cations; Channelrhodopsins; Cocaine; Dose-Response Relationship, Drug; Dronabinol; Ethanol; Gadolinium; HEK293 Cells; Humans; Illicit Drugs; Magnesium; Membrane Potentials; Membrane Transport Modulators; Methamphetamine; Morphine; Nicotine; Patch-Clamp Techniques; Tetrodotoxin; Toluene; Transfection | 2018 |
Prolonged abstinence from cocaine or morphine disrupts separable valuations during decision conflict.
Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Conflict, Psychological; Decision Making; Male; Mice; Mice, Inbred C57BL; Morphine | 2018 |
Naltrexone and nalmefene attenuate cocaine place preference in male mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Opioid; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists | 2018 |
Conditioned aversive responses produced by delayed, but not immediate, exposure to cocaine and morphine in male Sprague-Dawley rats.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Avoidance Learning; Cocaine; Conditioning, Classical; Cues; Male; Morphine; Rats; Rats, Sprague-Dawley; Saccharin; Taste; Time Factors | 2018 |
Pharmacological classification of centrally acting drugs using EEG in freely moving rats: an old tool to identify new atypical dopamine uptake inhibitors.
Topics: Animals; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Electroencephalography; Heroin; Ketamine; Male; Methylphenidate; Modafinil; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2019 |
Increased cocaine reward in offspring of females exposed to morphine during adolescence.
Topics: Age Factors; Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Female; Male; Morphine; Nucleus Accumbens; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward; Self Administration; Sex Characteristics | 2019 |
Ketamine Tolerance in Sprague-Dawley Rats after Chronic Administration of Ketamine, Morphine, or Cocaine.
Topics: Anesthetics; Animals; Cocaine; Drug Tolerance; Ketamine; Male; Morphine; Rats; Rats, Sprague-Dawley | 2019 |
Adolescence versus adulthood: Differences in basal mesolimbic and nigrostriatal dopamine transmission and response to drugs of abuse.
Topics: Age Factors; Analgesics, Opioid; Animals; Brain; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dronabinol; Ganglionic Stimulants; Male; Microdialysis; Morphine; Nicotine; Nucleus Accumbens; Psychotropic Drugs; Rats; Substance-Related Disorders; Synaptic Transmission | 2020 |
Detection of fentanyl and fentanyl analogues in biological samples using liquid chromatography-high resolution mass spectrometry.
Topics: Adult; Analgesics, Opioid; Central Nervous System Depressants; Chromatography, Liquid; Cocaine; Ethanol; Fentanyl; Humans; Mass Spectrometry; Middle Aged; Morphine; Opioid-Related Disorders; Substance Abuse Detection; Young Adult | 2019 |
Concomitant Heroin and Cocaine Use among Opioid-Dependent Patients during Methadone, Buprenorphine or Morphine Opioid Agonist Therapy.
Topics: Adult; Analgesics, Opioid; Behavior, Addictive; Buprenorphine; Cocaine; Cross-Sectional Studies; Delayed-Action Preparations; Female; Heroin; Humans; Male; Methadone; Morphine; Opiate Substitution Treatment; Opioid-Related Disorders; Switzerland | 2019 |
Application of a chemiluminescence immunoassay system and GC/MS for toxicological investigations on skeletonized human remains.
Topics: Amphetamines; Animals; Benzodiazepines; Body Remains; Cocaine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Immunoassay; Larva; Luminescent Measurements; Male; Morphine; Myocardium; Narcotics; Postmortem Changes; Substance Abuse Detection; Substance-Related Disorders; Young Adult | 2019 |
Differences in cocaine- and morphine-induced cognitive impairments and serum corticosterone between C57BL/6J and BALB/cJ mice.
Topics: Animals; Behavior, Animal; Cocaine; Cognitive Dysfunction; Corticosterone; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Morphine; Recognition, Psychology; Social Behavior; Social Learning; Species Specificity | 2019 |
Increased sensitivity to psychostimulants and GABAergic drugs in Lsamp-deficient mice.
Topics: Alprazolam; Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Ethanol; Female; GABA Modulators; Gene Knockout Techniques; GPI-Linked Proteins; Locomotion; Male; Maze Learning; Mice; Mice, Knockout; Morphine; Neuroprotective Agents; Phenotype; Receptors, GABA-A | 2019 |
Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal.
Topics: Animals; Cocaine; Excitatory Postsynaptic Potentials; Male; Mice, Transgenic; Morphine; Neuronal Plasticity; Neurons; Nucleus Accumbens; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2019 |
Disposable electrochemical immunosensor array for the multiplexed detection of the drug metabolites morphine, tetrahydrocannabinol and benzoylecgonine.
Topics: Antibodies; Cocaine; Dronabinol; Electrochemical Techniques; Gold; Humans; Illicit Drugs; Immobilized Proteins; Immunoassay; Limit of Detection; Metal Nanoparticles; Morphine; Substance Abuse Detection | 2019 |
Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids.
Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Central Nervous System Stimulants; Cocaine; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Nucleus Accumbens; Receptors, Dopamine D1; Receptors, Dopamine D2; Reward | 2020 |
Paternal morphine exposure induces bidirectional effects on cocaine versus opioid self-administration.
Topics: Acetylation; Analgesics, Opioid; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cocaine; Dopamine Uptake Inhibitors; Epigenesis, Genetic; Female; Histone Code; Male; Morphine; Motivation; Oxycodone; Paternal Exposure; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Self Administration; Seminiferous Tubules | 2020 |
Nicotine, cocaine, amphetamine, morphine, and ethanol increase norepinephrine output in the bed nucleus of stria terminalis of freely moving rats.
Topics: Amphetamine; Animals; Cocaine; Drug-Seeking Behavior; Ethanol; Male; Morphine; Nicotine; Norepinephrine; Rats; Septal Nuclei | 2021 |
Alcohol inhibits morphine/cocaine reward memory acquisition and reconsolidation in rats.
Topics: Animals; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Memory; Morphine; Rats; Rats, Sprague-Dawley; Reward | 2020 |
Differential genetic risk for methamphetamine intake confers differential sensitivity to the temperature-altering effects of other addictive drugs.
Topics: Amphetamine-Related Disorders; Analgesics, Opioid; Animals; Cocaine; Dopamine Agents; Female; Genotype; Hypothermia; Male; Methamphetamine; Mice; Mice, Inbred Strains; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Thermosensing | 2020 |
Stability and Degradation Pathways of Different Psychoactive Drugs in Neat and in Buffered Oral Fluid.
Topics: Amphetamine; Cocaine; Codeine; Drug Stability; Forensic Toxicology; Illicit Drugs; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Specimen Handling; Substance Abuse Detection | 2020 |
Revealing the Kinetic Advantage of a Competitive Small-Molecule Immunoassay by Direct Detection.
Topics: Antibodies; Binding, Competitive; Cocaine; Immunoassay; Kinetics; Methadone; Morphine; Small Molecule Libraries | 2020 |
Suppressing effect of the novel positive allosteric modulator of the GABA
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; GABA Modulators; Hyperkinesis; Locomotion; Male; Mice; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Receptors, GABA-B | 2021 |
Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure in male mice.
Topics: Animals; Cocaine; Male; Mice; Mice, Inbred C57BL; Morphine; Nucleus Accumbens; Receptors, Metabotropic Glutamate | 2021 |
Exogenous SO
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Humans; Memory Consolidation; Mice, Inbred C57BL; Morphine; Morphine Dependence; Reward; Sulfites; Sulfur Dioxide; Time Factors | 2021 |
Evaluation of the diagnostic performance of an oral fluid screening test device for substance abuse at traffic controls.
Topics: Amphetamines; Cocaine; Data Accuracy; Driving Under the Influence; Dronabinol; Equipment Failure Analysis; Female; Forensic Toxicology; Humans; Illicit Drugs; Immunoassay; Male; Methamphetamine; Morphine; Nordazepam; Plasma; Predictive Value of Tests; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry | 2021 |
Determination of Drugs of Abuse in Hair by LC-MS-MS: Application to Suicide Attempts Investigation.
Topics: Amphetamines; Chromatography, Liquid; Cocaine; Codeine; Dronabinol; Hair; Humans; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Suicide, Attempted; Tandem Mass Spectrometry | 2022 |
Psychostimulants and opioids differentially influence the epigenetic modification of histone acetyltransferase and histone deacetylase in astrocytes.
Topics: Acetylation; Astrocytes; Central Nervous System Stimulants; Cocaine; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Histone Acetyltransferases; Histone Deacetylases; Humans; Methamphetamine; Morphine; Piracetam; Primary Cell Culture; Up-Regulation | 2021 |
Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells.
Topics: Analgesics, Opioid; Astrocytes; Cells, Cultured; Central Nervous System Stimulants; Cocaine; Epigenesis, Genetic; Histone Deacetylases; Humans; Methamphetamine; Morphine; Neuroglia; Nootropic Agents; Piracetam; Sirtuins | 2021 |
JQ1 attenuates psychostimulant- but not opioid-induced conditioned place preference.
Topics: Amphetamine; Anesthetics, Local; Animals; Azepines; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Epigenomics; Learning; Male; Memory; Mice; Morphine; Nicotine; Triazoles | 2022 |
Hippocampus-sensitive and striatum-sensitive learning one month after morphine or cocaine exposure in male rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Hippocampus; Male; Maze Learning; Morphine; Rats | 2022 |
Common opioids and stimulants in autopsy and DUID cases: A comparison of measured concentrations.
Topics: Amphetamine; Analgesics, Opioid; Autopsy; Central Nervous System Stimulants; Cocaine; Coma; Heroin; Humans; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Substance-Related Disorders | 2022 |
Consumption of common illicit drugs in twenty-one cities in southwest China through wastewater analysis.
Topics: China; Chromatography, Liquid; Cities; Cocaine; Codeine; Heroin; Illicit Drugs; Ketamine; Methamphetamine; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2022 |
Residues of ractopamine, a livestock feed additive, in meat might alleviate misuse of cocaine, nicotine, methamphetamine, and morphine.
Topics: Animal Feed; Animals; Cocaine; Humans; Meat; Methamphetamine; Morphine; Nicotine; Substance-Related Disorders; United States | 2023 |
Exposure to Morphine and Cocaine Modify the Transcriptomic Landscape in Zebrafish Embryos.
Topics: Animals; Cocaine; Morphine; Receptors, Opioid; Transcriptome; Zebrafish | 2022 |
Reduced dopamine release in Dcc haploinsufficiency male mice abolishes the rewarding effects of cocaine but not those of morphine and ethanol.
Topics: Animals; Cocaine; DCC Receptor; Dopamine; Ethanol; Haploinsufficiency; Male; Mice; Morphine; Nucleus Accumbens; Receptors, Cell Surface; Tumor Suppressor Proteins | 2023 |
From Bumps to Binges: Overview of Deaths Associated with Cocaine in England, Wales and Northern Ireland (2000-2019).
Topics: Cocaine; Cocaine-Related Disorders; England; Humans; Morphine; Northern Ireland; Substance-Related Disorders; Wales | 2023 |
Letter-to-the-editor, concerning the article entitled "Common opioids and stimulants in autopsy and DUID cases: A comparison of measured concentrations."
Topics: Amphetamine; Analgesics, Opioid; Autopsy; Central Nervous System Stimulants; Cocaine; Methadone; Morphine; Substance Abuse Detection | 2023 |
Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome.
Topics: Analgesics, Opioid; Animals; Cocaine; Mice; Morphine; Nucleus Accumbens; Proteome | 2023 |
Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring.
Topics: Analgesics, Opioid; Animals; Cocaine; Female; Humans; Male; Morphine; Pain; Paternal Exposure; Rats | 2023 |
Doxycycline diminishes the rewarding and psychomotor effects induced by morphine and cocaine.
Topics: Animals; Cocaine; Doxycycline; Mice; Morphine; Reward; Substance-Related Disorders | 2024 |
Investigating the Influence of Morphine and Cocaine on the Mesolimbic Pathway Using a Novel Microimaging Platform.
Topics: Animals; Cocaine; Dopamine; Mice; Morphine; Nucleus Accumbens; Ventral Tegmental Area | 2023 |
Analysis of meconium for cocaine in neonates.
Topics: Chromatography, High Pressure Liquid; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Prenatal Exposure Delayed Effects | 1992 |
Measurement of gestational cocaine exposure: sensitivity of infants' hair, meconium, and urine.
Topics: Adult; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Meconium; Pregnancy; Pregnancy Complications; Radioimmunoassay; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 1992 |
Meconium for drug testing.
Topics: Cocaine; Female; Humans; Illicit Drugs; Infant, Newborn; Meconium; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Substance-Related Disorders | 1991 |
Incidence of intrauterine cocaine exposure in a suburban setting.
Topics: Cocaine; Female; Fetus; Humans; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Substance-Related Disorders; Suburban Population; Surveys and Questionnaires | 1991 |
Perinatal outcome after recent cocaine usage.
Topics: Amniotic Fluid; Cocaine; Female; Fetal Membranes, Premature Rupture; Humans; Incidence; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Substance-Related Disorders | 1990 |
False-positive and false-negative rates in meconium drug testing.
Topics: Amphetamines; Cocaine; Dronabinol; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; False Positive Reactions; Female; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Humans; Meconium; Narcotics; Pharmaceutical Preparations; Pregnancy; Substance Abuse Detection | 1995 |
Intensive surveillance for cocaine use in obstetric patients.
Topics: Cocaine; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Prospective Studies; Substance Abuse Detection; Substance-Related Disorders | 1995 |
Relation between meconium concentration of the cocaine metabolite benzoylecgonine and fetal growth.
Topics: Birth Weight; Cocaine; Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Linear Models; Meconium; Pregnancy; Prenatal Exposure Delayed Effects | 1995 |
Detection of cocaine, norcocaine, and cocaethylene in the meconium of premature neonates.
Topics: Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Premature; Male; Meconium; Pregnancy; Pregnancy Complications; Prospective Studies; Substance Abuse Detection; Urine | 1994 |
Maternal cocaine use without evidence of fetal exposure.
Topics: Adult; Cocaine; Cotinine; Female; Hair; Humans; Infant, Newborn; Meconium; Mothers; Narcotics; Nicotine; Placenta; Pregnancy; Smoking; Substance Abuse, Intravenous | 1994 |
Detection of cocaine exposure in the neonate. Analyses of urine, meconium, and amniotic fluid from mothers and infants exposed to cocaine.
Topics: Adult; Amniotic Fluid; Cocaine; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Pregnancy Complications; Substance Abuse Detection | 1994 |
Cocaethylene in meconium specimens.
Topics: Cocaine; Cross Reactions; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Meconium | 1994 |
Determination of cocaine usage in pregnant women by a urinary EMIT drug screen and GC-MS analyses.
Topics: Cocaine; Enzyme Multiplied Immunoassay Technique; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Substance Abuse Detection | 1994 |
Neonatal outcome in infants with evidence of fetal exposure to opiates, cocaine, and cannabinoids.
Topics: Cannabinoids; Cocaine; Female; Humans; Infant, Newborn; Meconium; Narcotics; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Substance-Related Disorders | 1994 |
Cocaine and metabolites in amniotic fluid may prolong fetal drug exposure.
Topics: Absorption; Amniotic Fluid; Animals; Cocaine; Deglutition; Female; Fetal Blood; Fetus; Meconium; Pregnancy; Sheep | 1994 |
Meconium analysis for improved identification of infants exposed to cocaine in utero.
Topics: Cannabis; Cocaine; Female; Forecasting; Gestational Age; Humans; Income; Infant, Newborn; Insurance, Health; Maternal Age; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Risk Factors; Sensitivity and Specificity; Substance-Related Disorders | 1994 |
Prenatal drug use in Minneapolis-St Paul, Minn. A 4-year trend.
Topics: Adolescent; Adult; Birth Weight; Cocaine; Dronabinol; Female; Health Promotion; Humans; Infant, Newborn; Infant, Premature; Meconium; Minnesota; Narcotics; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prevalence; Smoking; Socioeconomic Factors; Substance Abuse Detection; Substance-Related Disorders | 1994 |
A comparison of meconium, maternal urine and neonatal urine for detection of maternal drug use during pregnancy.
Topics: Adult; Cocaine; Dronabinol; Female; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Infant, Newborn; Meconium; Methadone; Narcotics; New York City; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prevalence; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders | 1994 |
Postmortem drug analysis of meconium in early-gestation human fetuses exposed to cocaine: clinical implications.
Topics: Animals; Cocaine; Female; Fetal Death; Fetus; Humans; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Substance-Related Disorders | 1994 |
m-Hydroxybenzoylecgonine: an important contributor to the immunoreactivity in assays for benzoylecgonine in meconium.
Topics: Artifacts; Cocaine; Humans; Immunoassay; Meconium | 1993 |
Solid-phase extraction and GC/MS quantitation of cocaine, ecgonine methyl ester, benzoylecgonine, and cocaethylene from meconium, whole blood, and plasma.
Topics: Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Meconium; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors | 1993 |
Quantitation of benzoylnorecgonine and other cocaine metabolites in meconium by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Substance-Related Disorders | 1993 |
Meconium testing for cocaine metabolite: prevalence, perceptions, and pitfalls.
Topics: Birth Weight; Cocaine; Female; Humans; Infant, Newborn; Meconium; Nurses; Pregnancy; Pregnancy Complications; Prenatal Care; Prevalence; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Suburban Population; Urban Population | 1993 |
Gastric fluid analysis for determining gestational cocaine exposure.
Topics: Amniotic Fluid; Case-Control Studies; Cocaine; Female; Gastric Juice; Humans; Infant, Newborn; Meconium; Neonatal Screening; Pregnancy; Pregnancy Complications; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1996 |
[Value of toxicological research in newborn infants of addicted mothers by the study of several samples (urine, meconium, hair)].
Topics: Cannabis; Cocaine; Female; Hair; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Meconium; Narcotics; Neonatal Abstinence Syndrome; Pregnancy; Pregnancy Complications; Substance-Related Disorders | 1996 |
Prenatal cocaine and neonatal outcome: evaluation of dose-response relationship.
Topics: Adult; Cocaine; Dose-Response Relationship, Drug; Female; Humans; Infant Behavior; Infant, Newborn; Interviews as Topic; Male; Meconium; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Regression Analysis; Substance-Related Disorders; Urban Population | 1996 |
Cocaine disposition in meconium from newborns of cocaine-abusing mothers and urine of adult drug users.
Topics: Adult; Cocaine; Cross Reactions; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Male; Meconium; Middle Aged; Pregnancy; Prenatal Exposure Delayed Effects; Reference Standards; Substance-Related Disorders | 1996 |
The resurgence of congenital syphilis: a cocaine-related problem.
Topics: Adult; Cocaine; Female; Fluorescent Treponemal Antibody-Absorption Test; Humans; Incidence; Infant, Newborn; Male; Marijuana Abuse; Meconium; Opioid-Related Disorders; Risk Factors; Syphilis, Congenital | 1997 |
Mortality within the first 2 years in infants exposed to cocaine, opiate, or cannabinoid during gestation.
Topics: Birth Weight; Cannabinoids; Cannabis; Cocaine; Confidence Intervals; Data Interpretation, Statistical; Female; Humans; Infant; Infant Mortality; Infant, Newborn; Male; Meconium; Narcotics; Neonatal Screening; Odds Ratio; Opioid-Related Disorders; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Registries; Sudden Infant Death | 1997 |
Identification and analysis of the major metabolites of cocaine in meconium.
Topics: Cocaine; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Substance Abuse Detection | 1999 |
Level of in utero cocaine exposure and neonatal ultrasound findings.
Topics: Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Echoencephalography; Female; Fetus; Humans; Infant, Newborn; Intracranial Hemorrhages; Longitudinal Studies; Meconium; Odds Ratio; Pregnancy; Pregnancy Complications; Prospective Studies; Risk Factors | 1999 |
m-hydroxy benzoylecgonine recovery in fetal guinea pigs.
Topics: Amniotic Fluid; Animals; Cocaine; Female; Fetus; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Intestinal Mucosa; Intestines; Maternal-Fetal Exchange; Meconium; Metabolic Clearance Rate; Pregnancy; Tissue Distribution | 2000 |
Tone abnormalities are associated with maternal cigarette smoking during pregnancy in in utero cocaine-exposed infants.
Topics: Cocaine; Confounding Factors, Epidemiologic; Cotinine; Female; Humans; Infant; Infant, Newborn; Logistic Models; Male; Meconium; Muscle Hypertonia; Nervous System Diseases; Neurologic Examination; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Smoking | 2000 |
The Maternal Lifestyle Study: drug use by meconium toxicology and maternal self-report.
Topics: Adolescent; Adult; Amphetamines; Birth Weight; Cannabinoids; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Life Style; Longitudinal Studies; Meconium; Narcotics; Phencyclidine; Pregnancy; Pregnancy Complications; Substance-Related Disorders | 2001 |
Developing language skills of cocaine-exposed infants.
Topics: Analysis of Variance; Cocaine; Cocaine-Related Disorders; Female; Humans; Infant; Infant, Newborn; Language Development Disorders; Language Tests; Longitudinal Studies; Male; Meconium; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Regression Analysis; Statistics, Nonparametric | 2001 |
The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study.
Topics: Cannabinoids; Cocaine; Female; Hair; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Meconium; Placenta; Placental Circulation; Pregnancy; Twins, Dizygotic; Twins, Monozygotic | 2001 |
Maternal cocaine use: estimated effects on mother-child play interactions in the preschool period.
Topics: Adult; Child, Preschool; Cocaine; Cocaine-Related Disorders; Cohort Studies; Depression; Female; Follow-Up Studies; Humans; Infant, Newborn; Maternal Behavior; Meconium; Mother-Child Relations; Mothers; Play and Playthings; Pregnancy; Prenatal Exposure Delayed Effects; Videotape Recording | 2002 |
Level of prenatal cocaine exposure and scores on the Bayley Scales of Infant Development: modifying effects of caregiver, early intervention, and birth weight.
Topics: Birth Weight; Boston; Cannabis; Caregivers; Child Development; Cocaine; Confounding Factors, Epidemiologic; Female; Humans; Infant, Newborn; Linear Models; Longitudinal Studies; Meconium; Models, Statistical; Multivariate Analysis; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Psychomotor Performance; Risk Factors; Surveys and Questionnaires; Tobacco Smoke Pollution | 2002 |
Influence of prenatal cocaine exposure on early language development: longitudinal findings from four months to three years of age.
Topics: Case-Control Studies; Child, Preschool; Cocaine; Cocaine-Related Disorders; Female; Humans; Infant; Infant, Newborn; Language Development Disorders; Language Tests; Longitudinal Studies; Meconium; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects | 2003 |
Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse.
Topics: Cannabis; Cocaine; Hair; Humans; Illicit Drugs; Infant, Newborn; Linear Models; Meconium; Narcotics; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Neonatal hair analysis contribution to establishing a gestational drug exposure profile and predicting a withdrawal syndrome.
Topics: Cannabinoids; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Pregnancy; Substance Abuse Detection | 2003 |
Development and validation of a liquid chromatography-mass spectrometry assay for the determination of opiates and cocaine in meconium.
Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Humans; Infant, Newborn; Meconium; Narcotics; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2003 |
Abnormal auditory brainstem response among infants with prenatal cocaine exposure.
Topics: Case-Control Studies; Cocaine; Cocaine-Related Disorders; Evoked Potentials, Auditory, Brain Stem; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Prenatal Exposure Delayed Effects | 2004 |
Application of a validated high-performance liquid chromatography-mass spectrometry assay to the analysis of m- and p-hydroxybenzoylecgonine in meconium.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Infant, Newborn; Meconium; Spectrometry, Mass, Electrospray Ionization | 2005 |
Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project".
Topics: Abortion, Induced; Adult; Arecoline; Body Height; Cholinergic Agonists; Cocaine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Gravidity; Hallucinogens; Humans; Infant, Low Birth Weight; Infant, Newborn; Italy; Marijuana Smoking; Maternal-Fetal Exchange; Meconium; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Pregnancy; Smoking; Spain; Substance Abuse Detection; Substance-Related Disorders | 2005 |
Testing for fetal exposure to illicit drugs using umbilical cord tissue vs meconium.
Topics: Amphetamines; Cannabinoids; Cocaine; Female; Fetus; Humans; Meconium; Narcotics; Phencyclidine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Reproducibility of Results; ROC Curve; Substance Abuse Detection; Substance-Related Disorders; Umbilical Cord | 2006 |
Cocaine detection in maternal and neonatal hair: implications to fetal toxicology.
Topics: Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Hair; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Substance Abuse Detection; Time Factors | 2007 |
Prenatal cocaine and tobacco effects on children's language trajectories.
Topics: Adult; Child; Child, Preschool; Cocaine; Cocaine-Related Disorders; Female; Humans; Infant; Language Development; Language Development Disorders; Longitudinal Studies; Meconium; Pregnancy; Prenatal Exposure Delayed Effects; Smoking | 2007 |
A liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 20 drugs of abuse and metabolites in human meconium.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Feces; Humans; Infant, Newborn; Meconium; Narcotics; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2009 |
Comparison of drugs of abuse detection in meconium by EMIT II and ELISA.
Topics: Amphetamines; Analgesics, Opioid; Barbiturates; Benzodiazepines; Cannabinoids; Chromatography, Liquid; Cocaine; Dextropropoxyphene; Enzyme Multiplied Immunoassay Technique; Enzyme-Linked Immunosorbent Assay; False Positive Reactions; Female; Fetus; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Methadone; Phencyclidine Abuse; Pregnancy; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2009 |
Cocaine and opiates use in pregnancy: detection of drugs in neonatal meconium and urine.
Topics: Adult; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Indicators and Reagents; Infant, Newborn; Meconium; Narcotics; Pregnancy; Pregnancy Complications; Reproducibility of Results; Substance Abuse Detection | 2009 |
Opioid detection in maternal and neonatal hair and meconium: characterization of an at-risk population and implications to fetal toxicology.
Topics: Analgesics, Opioid; Cocaine; Ethanol; Fatty Acids; Female; Fetal Alcohol Spectrum Disorders; Fetus; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Narcotics; Oxycodone; Population Groups; Pregnancy; Pregnancy Complications; Risk; Substance Abuse Detection; Substance-Related Disorders | 2010 |
Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome.
Topics: Adult; Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Female; Gestational Age; Humans; Infant, Newborn; Length of Stay; Meconium; Methadone; Narcotics; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Opioid-Related Disorders; Predictive Value of Tests; Pregnancy; Pregnancy Complications; Premature Birth; Prenatal Exposure Delayed Effects; Prospective Studies; Substance Abuse Detection; Young Adult | 2010 |
Drugs of abuse detection in meconium: a comparison between ELISA and biochip microarray.
Topics: Cannabinoids; Chromatography, Liquid; Cocaine; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Infant, Newborn; Meconium; Methamphetamine; Protein Array Analysis; Substance Abuse Detection; Tandem Mass Spectrometry | 2011 |
[Alternative biological materials to detect prenatal exposure to drugs of abuse in the third trimester of pregnancy].
Topics: Adult; Amphetamines; Analgesics, Opioid; Cannabinoids; Cocaine; Female; Hair; Humans; Illicit Drugs; Meconium; Pregnancy; Pregnancy Trimester, Third; Substance-Related Disorders | 2012 |
Alternative matrices for cocaine, heroin, and methadone in utero drug exposure detection.
Topics: Chromatography, Liquid; Cocaine; Drug Monitoring; Female; Hair; Heroin; Humans; Maternal-Fetal Exchange; Meconium; Methadone; Placenta; Pregnancy; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord; Uterus | 2013 |
Rates of fetal polydrug exposures in methadone-maintained pregnancies from a high-risk population.
Topics: Adult; Cocaine; Female; Humans; Infant, Newborn; Meconium; Methadone; Opiate Substitution Treatment; Pregnancy | 2013 |
Development and practical application of accelerated solvent extraction for the isolation of cocaine/crack biomarkers in meconium samples.
Topics: Biomarkers; Chemical Fractionation; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Limit of Detection; Linear Models; Meconium; Neonatal Screening | 2014 |
Retrospective analysis of the diagnostic yield of newborn drug testing.
Topics: Adolescent; Adult; Amphetamines; Analgesics, Opioid; Benzodiazepines; Cocaine; Dronabinol; Female; Humans; Illicit Drugs; Infant, Newborn; Meconium; Pregnancy; Prenatal Care; Retrospective Studies; Risk Factors; Smoking; Substance Abuse Detection; Substance-Related Disorders; Urinalysis; Young Adult | 2014 |
Patterns of Drugs and Drug Metabolites Observed in Meconium: What Do They Mean?
Topics: Cocaine; Humans; Infant, Newborn; Meconium; Pharmaceutical Preparations | 2015 |
Drugs of abuse in maternal hair and paired neonatal meconium: an objective assessment of foetal exposure to gestational consumption.
Topics: Adult; Anesthetics, Local; Central Nervous System Stimulants; Cocaine; Female; Hair; Humans; Illicit Drugs; Infant, Newborn; Maternal Exposure; Meconium; Methamphetamine; Pregnancy; Prospective Studies; Substance Abuse Detection; Young Adult | 2016 |
Analysis of cocaine/crack biomarkers in meconium by LC-MS.
Topics: Biomarkers; Chromatography, Liquid; Crack Cocaine; Humans; Infant, Newborn; Limit of Detection; Linear Models; Mass Spectrometry; Meconium; Reproducibility of Results | 2016 |
Bioanalysis for cocaine, opiates, methadone, and amphetamines exposure detection during pregnancy.
Topics: Amphetamines; Analgesics, Opioid; Anesthetics, Local; Central Nervous System Stimulants; Cocaine; Female; Hair; Humans; Infant, Newborn; Meconium; Methadone; Opiate Alkaloids; Pregnancy; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord | 2017 |
Stability of 21 Cocaine, Opioid and Benzodiazepine Drug Analytes in Spiked Meconium at Three Temperatures.
Topics: Analgesics, Opioid; Benzodiazepines; Calibration; Cocaine; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Limit of Detection; Meconium; Specimen Handling | 2017 |
Comparison of Biological Screening and Diagnostic Indicators to Detect In Utero Opiate and Cocaine Exposure Among Mother-Infant Dyads.
Topics: Biological Assay; Cocaine; Cohort Studies; Female; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Narcotics; Opiate Alkaloids; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Retrospective Studies; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 2017 |
Quantitation of Cocaine and Metabolites, Phencyclidine, Butalbital and Phenobarbital in Meconium by Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Barbiturates; Biotransformation; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Female; Humans; Limit of Detection; Meconium; Pentobarbital; Phencyclidine; Phencyclidine Abuse; Predictive Value of Tests; Pregnancy; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Workflow | 2018 |
Salt-Assisted Liquid-Liquid Extraction of Meconium for Analysis of Cocaine and Amphetamines by Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Amphetamines; Chromatography, Liquid; Cocaine; Humans; Liquid-Liquid Extraction; Meconium; Salts; Substance Abuse Detection; Tandem Mass Spectrometry | 2019 |
Screening for Opioid and Stimulant Exposure In Utero Through Targeted and Untargeted Metabolomics Analysis of Umbilical Cords.
Topics: Analgesics, Opioid; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Female; Humans; Meconium; Metabolomics; Methadone; Neonatal Abstinence Syndrome; Pregnancy; Prospective Studies; Substance Abuse Detection; Tandem Mass Spectrometry; Umbilical Cord | 2020 |
Can Umbilical Cord and Meconium Results Be Directly Compared? Analytical Approach Matters.
Topics: Cocaine; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Retrospective Studies; Substance Abuse Detection; Umbilical Cord | 2023 |