cocaine and modafinil

cocaine has been researched along with modafinil in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.64)	18.2507
2000's	19 (31.15)	29.6817
2010's	35 (57.38)	24.3611
2020's	6 (9.84)	2.80

Authors

Authors	Studies
He, R; Johnson, KM; Kozikowski, AP; Ye, Y; Zhou, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cao, J; Katz, JL; Kopajtic, T; Newman, AH; Okunola, OM; Prisinzano, TE; Shook, M	1
Bakare, OM; Bi, GH; Bonifazi, A; Burzynski, C; Cao, J; Ellenberger, MP; He, Y; Kopajtic, T; Loland, CJ; Newman, AH; Rais, R; Slack, RD; Slusher, BS; Xi, ZX; Yano, H	1
Subbaiah, MAM	1
Bonifazi, A; Cao, J; Coggiano, MA; Giancola, JB; Haraczy, AJ; Ku, T; Lam, J; Newman, AH; Rais, R; Tanda, G	1
Balster, RL; Gold, LH	1
Bruins-Slot, L; Darnaudéry, M; Deroche-Gamonet, V; Le Moal, M; Piat, F; Piazza, PV	1
Hays, LR; Kelly, TH; Rush, CR; Wooten, AF	1
DeVane, CL; Donovan, JL; Malcolm, RJ; Markowitz, JS	1
Cornish, JW; Dackis, CA; Kampman, KM; Lynch, KG; O'Brien, CP; Poole, S; Rowan, A; Samaha, FF; White, L; Yu, E	1
Boutrel, B; Koob, GF	1
Chiang, CN; DeVane, CL; Donovan, JL; Elkashef, A; Malcolm, RJ; Mojsiak, J; Taylor, RM	1
Kosten, TR; Sofuoglu, M	1
Chiang, N; Cochran, K; DeVane, CL; Donovan, JL; Elkashef, A; Hedden, S; Khan, R; Malcolm, R; Mojsiak, J; Myrick, DL; Swayngim, K; Woolson, RF	1
Dopheide, MM; Miller, DK; Morgan, RE; Rodvelt, KR; Schachtman, TR	1
Foltin, RW; Haney, M; Hart, CL; Rubin, E; Vosburg, SK	2
Botrè, F; Colamonici, C; Strano-Rossi, S	1
Aubin, HJ; Benyamina, A; Coscas, S; Karila, L; Lépine, JP; Leroy, C; Lowenstein, W; Noble, F; Reynaud, M; Weinstein, A	1
Andersen, ML; Martins, RC; Shih, MC; Tufik, S	1
Fillmorex, MT; Hays, LR; Rush, CR; Vansickel, AR	1
Kampman, KM	1
Alexoff, D; Apelskog-Torres, K; Carter, P; Fowler, JS; Hooker, JM; Hubbard, B; Jayne, M; King, P; Logan, J; Muench, L; Shea, C; Telang, F; Volkow, ND; Wang, GJ; Warner, D; Wong, C; Xu, Y; Zhu, W	1
Berger, SP; Bernardi, RE; Lattal, KM; Lewis, JR	1
Cepeda, S; Knecht, C; Martínez-Raga, J	1
Malison, RT; Morgan, PT; Pace-Schott, E; Pittman, B; Stickgold, R	1
Dackis, C; O'Brien, CP	1
Caldarone, B; Fedolak, A; Ghavami, A; Hanania, T; Olivier, B; Paterson, NE	1
Lozama, A; Mello, NK; Negus, SS; Newman, JL; Prisinzano, TE	1
Bonab, AA; Clarke, A; Dougherty, DD; Fischman, AJ; Madras, BK; Martin, J; Mirto, T; Spencer, TJ	1
Aramini, TC; Bittencourt, LR; Borçoi, AR; Corrêa, JM; Fernandes, HA; Frussa-Filho, R; Fukushiro, DF; Hollais, AW; Kameda, SR; Procópio-Souza, R; Ribeiro, LT; Saito, LP; Santos, R; Talhati, F; Tufik, S; Wuo-Silva, R	1
Blanken, P; Hendriks, V; Nuijten, M; van den Brink, W	2
Reith, ME; Schmitt, KC	1
Dackis, CA; Kampman, KM; Lynch, KG; O'Brien, CP; Pettinati, HM; Plebani, JG; Sparkman, T	1
Castagné, V; Quinn, L; Virley, D; Wolinsky, T	1
Cao, J; Katz, JL; Kopajtic, T; Loland, CJ; Mazier, S; Mereu, M; Newman, AH; Okunola, OM; Prisinzano, TE; Shi, L; Tanda, G	1
Levin, FR; Mariani, JJ	1
O'Brien, CP	1
Anagnostaras, SG; Cai, DJ; Sage, JR; Shuman, T	1
Aston-Jones, G; Fallon, RV; Hensley-Simon, M; Kalivas, PW; LaLumiere, RT; Mahler, SV; Tahsili-Fahadan, P; Thomas, C	1
Buckley, NW; France, CP; Gosden, J; Hackett, D; Heal, DJ; Slater, N	1
Federici, M; Gu, HH; Latagliata, EC; Ledonne, A; Mercuri, NB; Nisticò, R; Puglisi-Allegra, S; Rizzo, FR; Romigi, A	1
Anagnostaras, SG; Sage, JR; Shuman, T; Wood, S	1
Docherty, JR; Killian, LM	1
De La Garza, R; Haile, CN; Mahoney, JJ; Newton, TF; Thompson-Lake, DG; Verrico, CD	1
Baumann, MH; Blough, BE; Hong, WC; Jones, KT; Katz, JL; Partilla, JS; Reith, ME; Rothman, RB; Schmitt, KC	1
Dackis, C; Kampman, KM; Lynch, KG; O'Brien, CP; Pettinati, HM; Spratt, K; Wierzbicki, MR	1
Baker, LE; Quisenberry, AJ	1
Bisagno, V; González, B; Urbano, FJ	1
Blanken, P; Goudriaan, AE; Hendriks, VM; Nuijten, M; Van den Brink, W	1
Chun, LE; Katz, JL; Mereu, M; Newman, AH; Prisinzano, TE; Tanda, G	1
Avelar, AJ; Beckstead, MJ; Cao, J; Newman, AH	1
Coggiano, MA; DeMarco, EM; Giancola, JB; Keighron, JD; Newman, AH; Shaffer, RJ; Slack, RD; Tanda, G	1
Giancola, JB; Keighron, JD; Lin, SC; Newman, AH; Scaglione, A; Tanda, G; Zanettini, C	1
Bi, GH; Chun, LE; Coggiano, MA; Hiranita, T; Jordan, CJ; Katz, JL; Keighron, JD; Lopez, JP; Mereu, M; Newman, AH; Quarterman, JC; Tanda, G; Xi, ZX	1
Arcadepani, FB; Bisaga, A; Fidalgo, TM; Gerra, G; Levin, FR; Tardelli, VS	1
Hempel, B; Hersey, M; Newman, AH; Tanda, G; Xi, ZX	1
Denson, RK; Foltin, RW; Haney, M; Rubin, E	1
Bartole, MK; Hersey, M; Jones, CS; Newman, AH; Tanda, G	1

Reviews

12 review(s) available for cocaine and modafinil

Article	Year
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges. Journal of medicinal chemistry, 2018, 03-22, Volume: 61, Issue:6 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Drug Design; Humans; Selective Serotonin Reuptake Inhibitors	2018
What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications. Sleep, 2004, Sep-15, Volume: 27, Issue:6 Topics: Amphetamine; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Humans; Methylphenidate; Modafinil; Narcolepsy; Nicotine; Sleep; Wakefulness	2004
Emerging pharmacological strategies in the fight against cocaine addiction. Expert opinion on emerging drugs, 2006, Volume: 11, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Drug Evaluation, Preclinical; Enzyme Inhibitors; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Humans; Modafinil; Nipecotic Acids; Propranolol; Randomized Controlled Trials as Topic; Tiagabine; Vaccines	2006
[Current pharmacotherapies and immunotherapy in cocaine addiction]. Presse medicale (Paris, France : 1983), 2008, Volume: 37, Issue:4 Pt 2 Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; GABA Agonists; Humans; Immunotherapy; Modafinil	2008
Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies. Current drug abuse reviews, 2008, Volume: 1, Issue:2 Topics: Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Induction; Humans; Metabolic Clearance Rate; Modafinil; Motivation; Neurotransmitter Agents; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Treatment Outcome	2008
Psychostimulant treatment of cocaine dependence. The Psychiatric clinics of North America, 2012, Volume: 35, Issue:2 Topics: Amphetamines; Animals; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Clinical Trials as Topic; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Dopamine Agents; Humans; Methylphenidate; Modafinil; Placebos; Rats; Reinforcement, Psychology; United States	2012
Psychostimulants and cognition: a continuum of behavioral and cognitive activation. Pharmacological reviews, 2014, Volume: 66, Issue:1 Topics: Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cocaine; Cognition; Humans; Methamphetamine; Methylphenidate; Modafinil	2014
Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter. Drug and alcohol dependence, 2015, Feb-01, Volume: 147 Topics: Animals; Benzhydryl Compounds; Benztropine; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Delivery Systems; Humans; Ligands; Modafinil; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary	2015
Cognitive enhancers versus addictive psychostimulants: The good and bad side of dopamine on prefrontal cortical circuits. Pharmacological research, 2016, Volume: 109 Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine; Humans; Methamphetamine; Methylphenidate; Modafinil; Nootropic Agents; Prefrontal Cortex; Substance-Related Disorders	2016
Prescription psychostimulants for the treatment of stimulant use disorder: a systematic review and meta-analysis. Psychopharmacology, 2020, Volume: 237, Issue:8 Topics: Amphetamine; Central Nervous System Stimulants; Cocaine; Double-Blind Method; Humans; Lisdexamfetamine Dimesylate; Methylphenidate; Modafinil; Prescription Drugs; Randomized Controlled Trials as Topic; Substance-Related Disorders; Treatment Outcome	2020
Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder. Current opinion in pharmacology, 2021, Volume: 56 Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; Humans; Modafinil	2021
Are There Prevalent Sex Differences in Psychostimulant Use Disorder? A Focus on the Potential Therapeutic Efficacy of Atypical Dopamine Uptake Inhibitors. Molecules (Basel, Switzerland), 2023, Jul-07, Volume: 28, Issue:13 Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Male; Modafinil; Sex Characteristics	2023

Trials

14 trial(s) available for cocaine and modafinil

Article	Year
Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study. Drug and alcohol dependence, 2003, May-01, Volume: 70, Issue:1 Topics: Adult; Benzhydryl Compounds; Blood Pressure; Body Temperature; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Humans; Male; Middle Aged; Modafinil; Pulse	2003
Modafinil influences the pharmacokinetics of intravenous cocaine in healthy cocaine-dependent volunteers. Clinical pharmacokinetics, 2005, Volume: 44, Issue:7 Topics: Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Modafinil; Patient Selection; Single-Blind Method	2005
Modafinil and cocaine interactions. The American journal of drug and alcohol abuse, 2006, Volume: 32, Issue:4 Topics: Benzhydryl Compounds; Blood Pressure; Cocaine; Cocaine-Related Disorders; Drug Interactions; Humans; Infusions, Intravenous; Modafinil; Neuroprotective Agents; Safety; Treatment Outcome	2006
Smoked cocaine self-administration is decreased by modafinil. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:4 Topics: Adult; Benzhydryl Compounds; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Male; Modafinil; Neuroprotective Agents; Pain Measurement; Self Administration; Surveys and Questionnaires; Time Factors	2008
Effects of potential agonist-replacement therapies for stimulant dependence on inhibitory control in cocaine abusers. The American journal of drug and alcohol abuse, 2008, Volume: 34, Issue:3 Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Female; Humans; Inhibition, Psychological; Male; Methylphenidate; Modafinil; Reaction Time	2008
Modafinil does not serve as a reinforcer in cocaine abusers. Drug and alcohol dependence, 2010, Jan-15, Volume: 106, Issue:2-3 Topics: Adult; Benzhydryl Compounds; Blood Pressure; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Modafinil; Neuroprotective Agents; Placebos; Reinforcement, Psychology; Sleep Wake Disorders	2010
Normalizing effects of modafinil on sleep in chronic cocaine users. The American journal of psychiatry, 2010, Volume: 167, Issue:3 Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Male; Middle Aged; Modafinil; Polysomnography; Sleep Wake Disorders; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Wakefulness	2010
A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride. Biological psychiatry, 2010, Nov-15, Volume: 68, Issue:10 Topics: Adolescent; Adult; Benzhydryl Compounds; Carbon Radioisotopes; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Middle Aged; Modafinil; Positron-Emission Tomography; Raclopride; Radioligand Assay	2010
Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): new pharmacological treatment options for crack-cocaine dependence in the Netherlands. BMC psychiatry, 2011, Aug-19, Volume: 11 Topics: Benzhydryl Compounds; Clinical Protocols; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Crack Cocaine; Delayed-Action Preparations; Dextroamphetamine; Fructose; Modafinil; Netherlands; Outcome and Process Assessment, Health Care; Topiramate	2011
A double-blind, placebo-controlled trial of modafinil for cocaine dependence. Journal of substance abuse treatment, 2012, Volume: 43, Issue:3 Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Modafinil; Sex Factors; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2012
Treatment with modafinil and escitalopram, alone and in combination, on cocaine-induced effects: a randomized, double blind, placebo-controlled human laboratory study. Drug and alcohol dependence, 2014, Aug-01, Volume: 141 Topics: Adult; Affect; Benzhydryl Compounds; Blood Pressure; Choice Behavior; Citalopram; Cocaine; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Male; Middle Aged; Modafinil; Selective Serotonin Reuptake Inhibitors	2014
Modafinil in the treatment of crack-cocaine dependence in the Netherlands: Results of an open-label randomised controlled feasibility trial. Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:6 Topics: Benzhydryl Compounds; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Crack Cocaine; Cytochrome P-450 CYP3A Inducers; Female; Humans; Male; Middle Aged; Modafinil; Netherlands; Patient Compliance; Patient Satisfaction; Treatment Outcome	2015
A double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence. Drug and alcohol dependence, 2015, Oct-01, Volume: 155 Topics: Adolescent; Adult; Alcoholism; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Craving; Double-Blind Method; Female; Humans; Male; Medication Adherence; Middle Aged; Modafinil; Patient Compliance; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult	2015
Impulsivity and attentional bias as predictors of modafinil treatment outcome for retention and drug use in crack-cocaine dependent patients: Results of a randomised controlled trial. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:7 Topics: Attention; Attentional Bias; Behavior, Addictive; Benzhydryl Compounds; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Crack Cocaine; Female; Humans; Impulsive Behavior; Male; Middle Aged; Modafinil; Nootropic Agents; Stroop Test; Treatment Outcome	2016

Other Studies

35 other study(ies) available for cocaine and modafinil

Article	Year
Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization. Journal of medicinal chemistry, 2004, Nov-18, Volume: 47, Issue:24 Topics: Animals; Benzhydryl Compounds; Biological Availability; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Design; In Vitro Techniques; Ligands; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Modafinil; Motor Activity; Nerve Endings; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Rats; Serotonin Plasma Membrane Transport Proteins; Symporters; Synaptosomes	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Structure-Activity Relationships at the Monoamine Transporters for a Novel Series of Modafinil (2-[(diphenylmethyl)sulfinyl]acetamide) Analogues. ACS medicinal chemistry letters, 2010, Oct-10, Volume: 2, Issue:1 Topics:	2010
Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors. Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23 Topics: Animals; Benzhydryl Compounds; Cells, Cultured; Chlorocebus aethiops; COS Cells; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Modafinil; Molecular Structure; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2016
Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability. European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Drug Stability; Guinea Pigs; Locomotion; Male; Mice; Microsomes, Liver; Modafinil; Molecular Structure; Piperidines; Rats, Sprague-Dawley; Receptors, sigma; Serotonin Plasma Membrane Transport Proteins; Sigma-1 Receptor; Structure-Activity Relationship	2020
Evaluation of the cocaine-like discriminative stimulus effects and reinforcing effects of modafinil. Psychopharmacology, 1996, Volume: 126, Issue:4 Topics: Adrenergic Agents; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ephedrine; Macaca mulatta; Male; Modafinil; Narcotics; Prazosin; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration	1996
Study of the addictive potential of modafinil in naive and cocaine-experienced rats. Psychopharmacology, 2002, Volume: 161, Issue:4 Topics: Animals; Behavior, Addictive; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Modafinil; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration	2002
Discriminative-stimulus effects of modafinil in cocaine-trained humans. Drug and alcohol dependence, 2002, Aug-01, Volume: 67, Issue:3 Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Modafinil; Surveys and Questionnaires	2002
Chiral analysis of d- and l-modafinil in human serum: application to human pharmacokinetic studies. Therapeutic drug monitoring, 2003, Volume: 25, Issue:2 Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Drug Interactions; Drug Stability; Humans; Male; Modafinil; Quality Control; Stereoisomerism	2003
Modafinil evokes striatal [(3)H]dopamine release and alters the subjective properties of stimulants. European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3 Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Male; Modafinil; Nicotine; Nomifensine; Rats; Rats, Sprague-Dawley	2007
Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for "in competition" anti-doping analysis. Analytica chimica acta, 2008, Jan-14, Volume: 606, Issue:2 Topics: Adult; Aminobutyrates; Benzhydryl Compounds; Calibration; Central Nervous System Stimulants; Cocaine; Crotonates; Doping in Sports; Ephedrine; Female; Gas Chromatography-Mass Spectrometry; Humans; Modafinil; Saliva; Selegiline; Substance Abuse Detection; Time Factors	2008
Effects of cocaine, methamphetamine and modafinil challenge on sleep rebound after paradoxical sleep deprivation in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2008, Volume: 41, Issue:1 Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Male; Methamphetamine; Modafinil; Rats; Rats, Wistar; Receptors, Dopamine; Sleep Deprivation; Sleep, REM	2008
The search for medications to treat stimulant dependence. Addiction science & clinical practice, 2008, Volume: 4, Issue:2 Topics: Amphetamine-Related Disorders; Benzhydryl Compounds; Brain; Bupropion; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Drug Approval; Humans; Methamphetamine; Modafinil; Propranolol; Psychotropic Drugs; Secondary Prevention; Substance Withdrawal Syndrome; Token Economy	2008
Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications. JAMA, 2009, Mar-18, Volume: 301, Issue:11 Topics: Adult; Benzhydryl Compounds; Brain; Carbon Radioisotopes; Caudate Nucleus; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Male; Middle Aged; Modafinil; Nucleus Accumbens; Pilot Projects; Positron-Emission Tomography; Putamen; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3; Substance-Related Disorders; Young Adult	2009
Modafinil reinstates a cocaine conditioned place preference following extinction in rats. Behavioural brain research, 2009, Dec-01, Volume: 204, Issue:1 Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Environment; Extinction, Psychological; Male; Modafinil; Motor Activity; Random Allocation; Rats; Rats, Sprague-Dawley; Space Perception; Time Factors	2009
Normalizing effects of modafinil on cocaine-induced sleep abnormalities. The American journal of psychiatry, 2010, Volume: 167, Issue:3 Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Humans; Modafinil; Polysomnography; Randomized Controlled Trials as Topic; Sleep Wake Disorders; Substance Withdrawal Syndrome	2010
Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents. Pharmacology, biochemistry, and behavior, 2010, Volume: 95, Issue:4 Topics: Animals; Benzhydryl Compounds; Biogenic Monoamines; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred C57BL; Modafinil; Motor Activity; Neurotransmitter Uptake Inhibitors; Random Allocation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Wakefulness	2010
Behavioral evaluation of modafinil and the abuse-related effects of cocaine in rhesus monkeys. Experimental and clinical psychopharmacology, 2010, Volume: 18, Issue:5 Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Macaca mulatta; Modafinil; Motivation; Self Administration	2010
Addictive potential of modafinil and cross-sensitization with cocaine: a pre-clinical study. Addiction biology, 2011, Volume: 16, Issue:4 Topics: Animals; Benzhydryl Compounds; Brain; Central Nervous System Sensitization; Central Nervous System Stimulants; Choice Behavior; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Mice; Modafinil; Motivation; Motor Activity; Neuronal Plasticity; Reward; Social Environment; Substance-Related Disorders	2011
The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PloS one, 2011, Volume: 6, Issue:10 Topics: Benzhydryl Compounds; Cell Line; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Modafinil; Mutation; Protein Binding; Protein Conformation	2011
Differential behavioral profiling of stimulant substances in the rat using the LABORAS™ system. Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:4 Topics: Animals; Automation; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dizocilpine Maleate; Drinking Behavior; Drug Evaluation, Preclinical; Feeding Behavior; Grooming; Ketamine; Male; Modafinil; Motor Activity; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar	2012
R-modafinil (armodafinil): a unique dopamine uptake inhibitor and potential medication for psychostimulant abuse. Biological psychiatry, 2012, Sep-01, Volume: 72, Issue:5 Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Male; Mice; Microdialysis; Modafinil; Nucleus Accumbens; Protein Binding; Substance-Related Disorders	2012
Modafinil-cocaine interactions: clinical implications. Biological psychiatry, 2012, Sep-01, Volume: 72, Issue:5 Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine Antagonists; Humans; Modafinil	2012
Interactions between modafinil and cocaine during the induction of conditioned place preference and locomotor sensitization in mice: implications for addiction. Behavioural brain research, 2012, Dec-01, Volume: 235, Issue:2 Topics: Animals; Benzhydryl Compounds; Central Nervous System Sensitization; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Locomotion; Male; Mice; Mice, Inbred C57BL; Modafinil; Multivariate Analysis; Reward; Sensitivity and Specificity; Time Factors	2012
Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addiction biology, 2014, Volume: 19, Issue:1 Topics: Amino Acid Transport System y+; Amino Acids; Analysis of Variance; Animals; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glutamates; Male; Microdialysis; Microinjections; Modafinil; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Wakefulness-Promoting Agents; Xanthenes	2014
A preclinical evaluation of the discriminative and reinforcing properties of lisdexamfetamine in comparison to D-amfetamine, methylphenidate and modafinil. Neuropharmacology, 2013, Volume: 73 Topics: Animals; Benzhydryl Compounds; Cocaine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Lisdexamfetamine Dimesylate; Methylphenidate; Modafinil; Rats; Reinforcement, Psychology; Self Administration	2013
Electrophysiological and amperometric evidence that modafinil blocks the dopamine uptake transporter to induce behavioral activation. Neuroscience, 2013, Nov-12, Volume: 252 Topics: Animals; Benzhydryl Compounds; Brain; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Mice; Mice, Mutant Strains; Modafinil; Motor Activity; Patch-Clamp Techniques; Wakefulness-Promoting Agents	2013
Cardiovascular stimulant actions of bupropion in comparison to cocaine in the rat. European journal of pharmacology, 2014, Jul-15, Volume: 735 Topics: Animals; Benzhydryl Compounds; Bupropion; Central Nervous System Stimulants; Cocaine; Desipramine; Electric Stimulation; Heart Ventricles; Hydroxamic Acids; In Vitro Techniques; Male; Modafinil; Myocardial Contraction; Nifedipine; Rats, Wistar; Vas Deferens	2014
Dopaminergic mediation of the discriminative stimulus functions of modafinil in rats. Psychopharmacology, 2015, Volume: 232, Issue:24 Topics: Amphetamine; Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dopamine; Dopamine Agents; Generalization, Psychological; Male; Methylphenidate; Modafinil; Nicotine; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Wakefulness-Promoting Agents	2015
The unique psychostimulant profile of (±)-modafinil: investigation of behavioral and neurochemical effects in mice. The European journal of neuroscience, 2017, Volume: 45, Issue:1 Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Male; Mice; Microdialysis; Modafinil	2017
Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons. Neuropharmacology, 2017, Sep-01, Volume: 123 Topics: Action Potentials; Animals; Autoreceptors; Benzhydryl Compounds; Benztropine; Cocaine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Male; Mesencephalon; Mice, Inbred DBA; Modafinil; Patch-Clamp Techniques; Receptors, Dopamine D2; Synaptic Transmission; Tissue Culture Techniques	2017
Distinct effects of (R)-modafinil and its (R)- and (S)-fluoro-analogs on mesolimbic extracellular dopamine assessed by voltammetry and microdialysis in rats. The European journal of neuroscience, 2019, Volume: 50, Issue:3 Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Microdialysis; Modafinil; Nucleus Accumbens; Rats, Sprague-Dawley	2019
Pharmacological classification of centrally acting drugs using EEG in freely moving rats: an old tool to identify new atypical dopamine uptake inhibitors. Neuropharmacology, 2019, 12-15, Volume: 161 Topics: Animals; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Electroencephalography; Heroin; Ketamine; Male; Methylphenidate; Modafinil; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu	2019
Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:9 Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dopamine; Dose-Response Relationship, Drug; Gap Junctions; Methylphenidate; Modafinil; Rats; Rats, Sprague-Dawley	2020
Modafinil reduces smoked cocaine self-administration in humans: effects vary as a function of cocaine 'priming' and cost. Drug and alcohol dependence, 2021, 04-01, Volume: 221 Topics: Adult; Alcoholism; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Cues; Double-Blind Method; Female; Humans; Male; Modafinil; Motor Activity; Self Administration	2021