Compounds > cocaine

cocaine and methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate

cocaine has been researched along with methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (10.00)	18.2507
2000's	8 (80.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Araldi, GL; Boja, J; Flippen-Anderson, JL; George, C; Johnson, KM; Kozikowski, AP; Meil, WM; Saiah, E	1
Enyedy, I; Flippen-Anderson, J; Johnson, KM; Kozikowski, AP; Smith, MP; Tamiz, AP; Zhang, M	1
Johnson, KM; Kozikowski, AP; Petukhov, PA; Tella, SR; Wang, CZ; Ye, YP; Zhang, J	1
He, R; Johnson, KM; Kozikowski, AP; Ye, Y; Zhou, J	1
Kozikowski, A; Ordway, GA; Paul, IA; Petukhov, P; Ranaldi, R; Wang, Z; Woolverton, WL	1
Araldi, GL; Balster, RL; Bandyopadhyay, BC; Beardsley, PM; Carmona, G; Deschaux, O; Johnson, KM; Kozikowski, AP; Munzar, P; Smith, MP; Tella, SR	1
Bandyopadhyay, BC; Flippen-Anderson, JL; Johnson, KM; Kozikowski, AP; Tamiz, AP; Tella, S; Wang, CZ; Zhang, J; Zhang, M	1
Johnson, KJ; Kozikowski, AP; Petukhov, PA; Tella, SR; Zhang, M	1
Johnson, KM; Kozikowski, AP; Petukhov, PA; Wang, CZ; Ye, YP; Zhang, J	1
Subbaiah, MAM	1

Reviews

1 review(s) available for cocaine and methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate

Article	Year
Triple Reuptake Inhibitors as Potential Therapeutics for Depression and Other Disorders: Design Paradigm and Developmental Challenges. Journal of medicinal chemistry, 2018, 03-22, Volume: 61, Issue:6 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Drug Design; Humans; Selective Serotonin Reuptake Inhibitors	2018

Other Studies

9 other study(ies) available for cocaine and methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate

Article	Year
Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton. Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11 Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperidines; Protein Binding; Rats; Stereoisomerism; Synaptosomes; Tropanes	1998
Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors. Bioorganic & medicinal chemistry letters, 2000, Aug-07, Volume: 10, Issue:15 Topics: Bridged Bicyclo Compounds, Heterocyclic; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship	2000
SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement. Journal of medicinal chemistry, 2002, Jul-18, Volume: 45, Issue:15 Topics: Animals; Brain; Carrier Proteins; Cocaine; Discrimination Learning; Dopamine; Dopamine Plasma Membrane Transport Proteins; Esters; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Models, Molecular; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters; Synaptosomes	2002
Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization. Journal of medicinal chemistry, 2004, Nov-18, Volume: 47, Issue:24 Topics: Animals; Benzhydryl Compounds; Biological Availability; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Design; In Vitro Techniques; Ligands; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Modafinil; Motor Activity; Nerve Endings; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Rats; Serotonin Plasma Membrane Transport Proteins; Symporters; Synaptosomes	2004
Reinforcing strength of a novel dopamine transporter ligand: pharmacodynamic and pharmacokinetic mechanisms. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: Animals; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Kinetics; Ligands; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Self Administration; Symporters	2002
Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1 Topics: Animals; Cocaine; Discrimination Learning; Humans; Infusions, Intravenous; Macaca mulatta; Mice; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Self Administration	2003
Pharmacological and behavioral analysis of the effects of some bivalent ligand-based monoamine reuptake inhibitors. Journal of medicinal chemistry, 2001, May-10, Volume: 44, Issue:10 Topics: Animals; Carrier Proteins; Cocaine; Crystallography, X-Ray; Discrimination Learning; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship; Symporters; Synaptosomes	2001
Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles. Bioorganic & medicinal chemistry letters, 2001, Aug-20, Volume: 11, Issue:16 Topics: Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oxadiazoles; Piperidines; Structure-Activity Relationship	2001
Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring. Journal of medicinal chemistry, 2004, Jun-03, Volume: 47, Issue:12 Topics: Animals; Binding Sites; Brain; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Rats; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters	2004