cocaine and memantine

cocaine has been researched along with memantine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's11 (55.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ho, A; Kreek, MJ; Maggos, CE; Spangler, R; Yuferov, VP; Zhou, Y1
Collins, ED; Fischman, MW; Foltin, RW; McDowell, DM; Ward, AS1
Bäckström, P; Hyytiä, P; Liljequist, S1
Balster, RL; Beardsley, PM; Bespalov, AY; Dravolina, OA; Zvartau, EE1
Balster, RL; Beardsley, PM; Bespalov, AY; Zvartau, EE1
Schmidt, WJ; Tzchentke, TM1
Budziszewska, B; Jaworska-Feil, L; Kajta, M; Lasoń, W1
Foltin, RW; Haney, M; Hart, CL; Vosburg, SK1
Beardsley, PM; Newman, JL1
Collins, ED; Foltin, RW; Haney, M; Vosburg, SK; Ward, AS1
Aguilar, MA; Castillo, A; Maldonado, C; Miñarro, J; Rodríguez-Arias, M1
Collins, ED; Foltin, RW; Haney, M; Vosberg, SK; Ward, AS1
Cherng, CG; Lin, KY; Lin, LC; Lu, RB; Yang, FR; Yu, L1
Alaghband, Y; Marshall, JF1
Alaghband, Y; Azarnia, S; Guzowski, JF; Khalaj, AJ; Marshall, JF; O'Dell, SJ1
Cryan, JF; Glennon, J; Moloney, RD; O'Connor, RM; Vlachou, S1
Aguilar, MA; Calpe-López, C; García-Pardo, MP; Miñarro, J1
Abulseoud, OA; Angebrandt, A; Montemitro, C; Pettorruso, M; Wang, TY1
Bisaga, A; Danysz, W; Foltin, RW1

Reviews

1 review(s) available for cocaine and memantine

ArticleYear
Mechanistic insights into the efficacy of memantine in treating certain drug addictions.
    Progress in neuro-psychopharmacology & biological psychiatry, 2021, 12-20, Volume: 111

    Topics: Animals; Brain; Cocaine; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Memantine; Neurons; Opiate Alkaloids; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders

2021

Trials

2 trial(s) available for cocaine and memantine

ArticleYear
An evaluation of the reinforcing effects of memantine in cocaine-dependent humans.
    Drug and alcohol dependence, 2005, Aug-01, Volume: 79, Issue:2

    Topics: Adult; Ambulatory Care; Cocaine; Cocaine-Related Disorders; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Memantine; N-Methylaspartate; Reinforcement, Psychology

2005
The effects of acute pretreatment with high-dose memantine on the cardiovascular and behavioral effects of cocaine in humans.
    Experimental and clinical psychopharmacology, 2007, Volume: 15, Issue:3

    Topics: Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Emotions; Excitatory Amino Acid Antagonists; Heart Rate; Humans; Male; Memantine; Self Administration

2007

Other Studies

17 other study(ies) available for cocaine and memantine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Effects of memantine alone and with acute 'binge' cocaine on hypothalamic-pituitary-adrenal activity in the rat.
    European journal of pharmacology, 1998, Jul-03, Volume: 352, Issue:1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Cocaine; Corticotropin-Releasing Hormone; Excitatory Amino Acid Antagonists; Hypothalamus; Male; Memantine; Pituitary Gland; Rats; Rats, Inbred F344; RNA, Messenger

1998
The effects of memantine on the subjective, reinforcing and cardiovascular effects of cocaine in humans.
    Behavioural pharmacology, 1998, Volume: 9, Issue:7

    Topics: Adult; Blood Pressure; Choice Behavior; Cocaine; Crack Cocaine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Excitatory Amino Acid Antagonists; Heart Rate; Humans; Male; Memantine; Middle Aged; Psychomotor Performance; Reinforcement, Psychology; Self Administration; Substance-Related Disorders; Surveys and Questionnaires

1998
Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats.
    European journal of pharmacology, 1999, Jul-28, Volume: 378, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration

1999
Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats.
    European journal of pharmacology, 2000, Mar-03, Volume: 390, Issue:3

    Topics: Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Memantine; Motor Activity; Piperazines; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2000
Effects of N-methyl-D-aspartate receptor antagonists on reinstatement of cocaine-seeking behavior by priming injections of cocaine or exposures to cocaine-associated cues in rats.
    Behavioural pharmacology, 2000, Volume: 11, Issue:1

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Injections, Intravenous; Male; Memantine; Nucleus Accumbens; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration

2000
Effects of the non-competitive NMDA-receptor antagonist memantine on morphine- and cocaine-induced potentiation of lateral hypothalamic brain stimulation reward.
    Psychopharmacology, 2000, Volume: 149, Issue:3

    Topics: Analgesics, Opioid; Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; Memantine; Morphine; Rats; Rats, Long-Evans; Reward

2000
Antidepressant drugs inhibit glucocorticoid receptor-mediated gene transcription - a possible mechanism.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Amantadine; Animals; Antidepressive Agents; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Cocaine; Corticosterone; Cyclic AMP; Cyclic GMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Imipramine; Lithium Chloride; Memantine; Mifepristone; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Glucocorticoid; Receptors, Steroid; Sulfonamides; Tamoxifen; Thionucleotides; Time Factors; Transcription, Genetic; Type C Phospholipases

2000
Effects of memantine, haloperidol, and cocaine on primary and conditioned reinforcement associated with cocaine in rhesus monkeys.
    Psychopharmacology, 2006, Volume: 185, Issue:2

    Topics: Animals; Cocaine; Conditioning, Classical; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Macaca mulatta; Male; Memantine; Reinforcement, Psychology

2006
Memantine increases cardiovascular but not behavioral effects of cocaine in methadone-maintained humans.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: Adult; Behavior; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Heart Rate; Hemodynamics; Heroin Dependence; Humans; Male; Memantine; Methadone; Narcotics; Patient Compliance

2006
Effect of memantine and CNQX in the acquisition, expression and reinstatement of cocaine-induced conditioned place preference.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, May-09, Volume: 31, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Memantine; Mice; Reinforcement, Psychology

2007
Memantine abolishes the formation of cocaine-induced conditioned place preference possibly via its IL-6-modulating effect in medial prefrontal cortex.
    Behavioural brain research, 2011, Jun-20, Volume: 220, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Anesthetics, Local; Animals; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Immunosuppressive Agents; Interleukin-1beta; Interleukin-6; Male; Memantine; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Prefrontal Cortex; Thalidomide; Tumor Necrosis Factor-alpha

2011
Common influences of non-competitive NMDA receptor antagonists on the consolidation and reconsolidation of cocaine-cue memory.
    Psychopharmacology, 2013, Volume: 226, Issue:4

    Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward

2013
Retrieval-induced NMDA receptor-dependent Arc expression in two models of cocaine-cue memory.
    Neurobiology of learning and memory, 2014, Volume: 116

    Topics: Animals; Brain; Cocaine; Cues; Cytoskeletal Proteins; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Memantine; Memory; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2014
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats.
    Neuropharmacology, 2015, Volume: 99

    Topics: Administration, Intravenous; Aging; Amino Acid Transport System X-AG; Animals; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Maternal Deprivation; Memantine; Rats; Receptors, N-Methyl-D-Aspartate; Reward; Riluzole; Self Administration; Stress, Psychological

2015
Role of N-methyl-D-aspartate receptors in the long-term effects of repeated social defeat stress on the rewarding and psychomotor properties of cocaine in mice.
    Behavioural brain research, 2019, 04-01, Volume: 361

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Male; Memantine; Mice; Mice, Inbred Strains; Psychological Distance; Receptors, N-Methyl-D-Aspartate; Reward; Social Behavior; Stress, Psychological

2019
Antagonism of glutamatergic NMDA and mGluR5 receptors decreases consumption of food in baboon model of binge-eating disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:11

    Topics: Animals; Appetite; Bulimia Nervosa; Candy; Conditioning, Operant; Consummatory Behavior; Dexfenfluramine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Antagonists; Female; Male; Memantine; Papio cynocephalus; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Serotonin Receptor Agonists; Sex Characteristics; Thiazoles; Weight Gain

2008