cocaine has been researched along with ly 379268 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Baptista, MA; Martin-Fardon, R; Weiss, F | 1 |
| Adewale, AS; Platt, DM; Spealman, RD | 1 |
| Kalivas, PW; Peters, J | 1 |
| Bossert, JM; Gray, SM; Lu, L; Shaham, Y; Uejima, JL | 1 |
| Bauzo, RM; Howell, LL; Kimmel, HL | 1 |
| Ashby, CR; Chun, L; Gardner, EL; Li, J; Li, X; Peng, XQ; Slusher, BS; Thomas, AG; Xi, ZX | 1 |
| Hao, Y; Martin-Fardon, R; Weiss, F | 1 |
| Ardecky, R; Conn, PJ; Cosford, ND; Dahl, R; Jin, X; Markou, A; Semenova, S; Sheffler, DJ; Yang, L | 1 |
| Lu, L; Rebec, GV; Steketee, JD; Sun, W; Xue, Y | 1 |
| Balado, E; Berson, N; Deroche-Gamonet, V; Fiancette, JF; Kasanetz, F; Lafourcade, M; Manzoni, OJ; Piazza, PV; Renault, P; Revest, JM | 1 |
| Cannella, N; Corsi, M; Corti, C; Deroche-Gamonet, V; Evrard, L; Halbout, B; Hansson, AC; Spanagel, R; Uhrig, S | 1 |
| Goldberg, SR; Justinova, Z; Le Foll, B; Markou, A; Redhi, GH | 1 |
| Beveridge, TJ; Blough, BE; Ferris, MJ; Jones, SR; Karkhanis, AN | 1 |
| Allain, F; Lévesque, D; Roberts, DCS; Samaha, AN | 1 |
| Chiu, AS; Gable, ES; Kim, J; Kippin, TE; Shin, CB; Szumlinski, KK; Templeton, TJ; Vieira, PA | 1 |
| Blough, BE; Czoty, PW; Landavazo, A; Nader, MA | 1 |
16 other study(ies) available for cocaine and ly 379268
| Article | Year |
|---|---|
Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer.
Topics: Amino Acids; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Reward; Secondary Prevention; Self Administration | 2004 |
Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Male; Motor Activity; Muscle Contraction; Muscle, Skeletal; Psychomotor Performance; Receptors, Metabotropic Glutamate; Saimiri; Secondary Prevention; Self Administration; Stimulation, Chemical; Substance Abuse, Intravenous | 2006 |
The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats.
Topics: Amino Acids; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Feeding Behavior; Male; Microinjections; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Self Administration | 2006 |
Systemic and central amygdala injections of the mGluR(2/3) agonist LY379268 attenuate the expression of incubation of cocaine craving.
Topics: Amino Acids; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Extinction, Psychological; Male; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Self Administration | 2007 |
Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys.
Topics: Amino Acids; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Caudate Nucleus; Cocaine; Conditioning, Psychological; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Extinction, Psychological; Infusions, Intravenous; Injections, Intramuscular; Male; Microdialysis; Reaction Time; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Saimiri; Self Administration; Time Factors | 2009 |
Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Glutamate Carboxypeptidase II; Glutamic Acid; Male; Microdialysis; Microinjections; Neuroprotective Agents; Nucleus Accumbens; Organophosphorus Compounds; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Sucrose; Sweetening Agents | 2010 |
Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Addictive; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Thiazoles | 2010 |
The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Biphenyl Compounds; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Transformed; Cocaine; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Extinction, Psychological; Feeding Behavior; Glutamic Acid; Humans; Indans; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Reward; Self Administration; Time Factors | 2010 |
Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recurrence; Self Administration; Ventral Tegmental Area | 2012 |
Prefrontal synaptic markers of cocaine addiction-like behavior in rats.
Topics: Amino Acids; Analysis of Variance; Animals; Biophysics; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Synaptic Depression; Male; Patch-Clamp Techniques; Prefrontal Cortex; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Self Administration; Substance-Related Disorders; Synapses | 2013 |
The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Gene Expression; Male; Mice; Mice, Knockout; Prosencephalon; Rats; Receptors, Metabotropic Glutamate; Self Administration | 2013 |
Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug Interactions; Drug-Seeking Behavior; Male; Nicotine; Receptors, Metabotropic Glutamate; Recurrence; Reinforcement, Psychology; Saimiri; Self Administration; Tobacco Use Disorder | 2016 |
The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Motivation; Phenmetrazine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Self Administration | 2016 |
Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation.
Topics: Amino Acids; Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Male; Models, Neurological; Motivation; Motor Activity; Rats, Wistar; Receptors, Metabotropic Glutamate; Self Administration; Time Factors | 2017 |
Endogenous glutamate within the prelimbic and infralimbic cortices regulates the incubation of cocaine-seeking in rats.
Topics: Amino Acids; Anesthetics, Local; Animals; Aspartic Acid; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Drug-Seeking Behavior; Excitatory Amino Acid Agents; Glutamic Acid; Male; Microdialysis; Microinjections; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2018 |
Effects of the mGluR2/3 receptor agonist LY379268 on the reinforcing strength of cocaine in rhesus monkeys.
Topics: Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Macaca mulatta; Male; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Self Administration | 2020 |