Compounds > cocaine

cocaine and losartan

cocaine has been researched along with losartan in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Knuepfer, MM; Reilly, NS; Schwartz, JA1
Bowman, TA; Knuepfer, MM; Kucenas, S; Ruhlman, M; Watanabe, MA1
Chung, YH; Ho, YS; Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Lee, YJ; Lei, XG; Mai, HN; Nah, SY; Nam, Y; Nguyen, TT; Shin, EJ; Yu, DY1
Correia, AT; Guimarães, LL; Roveri, V; Toma, W2
Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V1

Other Studies

9 other study(ies) available for cocaine and losartan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Angiotensin and NMDA receptors in the median preoptic nucleus mediate hemodynamic response patterns to stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Catheterization; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Losartan; Microinjections; Muscimol; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Stress, Physiological; Time Factors

2008
Angiotensin II and CRF receptors in the central nucleus of the amygdala mediate hemodynamic response variability to cocaine in conscious rats.
    Brain research, 2010, Jan-14, Volume: 1309

    Topics: Amygdala; Angiotensin II Type 1 Receptor Blockers; Animals; Cocaine; Cocaine-Related Disorders; Consciousness; Corticotropin-Releasing Hormone; Disease Models, Animal; Dopamine Uptake Inhibitors; GABA Agonists; Hemodynamics; Hormone Antagonists; Losartan; Male; Muscimol; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Corticotropin-Releasing Hormone; Vascular Resistance; Vasoconstriction

2010
Genetic depletion of glutathione peroxidase-1 potentiates nephrotoxicity induced by multiple doses of cocaine via activation of angiotensin II AT1 receptor.
    Free radical research, 2016, Volume: 50, Issue:4

    Topics: Animals; bcl-2-Associated X Protein; Chromones; Cocaine; Female; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Kidney; Losartan; Male; Malondialdehyde; Mice; Mice, Knockout; Morpholines; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Carbonylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptor, Angiotensin, Type 1; Signal Transduction; Thiocarbamates

2016
Occurrence of pharmaceuticals and cocaine in the urban drainage channels located on the outskirts of the São Vicente Island (São Paulo, Brazil) and related ecological risk assessment.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:38

    Topics: Acetaminophen; Brazil; Caffeine; Carbamazepine; Cocaine; Environmental Monitoring; Humans; Losartan; Pharmaceutical Preparations; Risk Assessment; Water Pollutants, Chemical

2022
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:42

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical

2022
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:59

    Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical

2022