cocaine has been researched along with lidocaine in 357 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 156 (43.70) | 18.7374 |
| 1990's | 108 (30.25) | 18.2507 |
| 2000's | 54 (15.13) | 29.6817 |
| 2010's | 32 (8.96) | 24.3611 |
| 2020's | 7 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Jolivette, LJ; Ward, KW | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Barash, P; Byck, R; Jatlow, P; Ungerer, J; Van Dyke, C | 2 |
| Panje, WR | 1 |
| Cheney, DL; Ngai, SH; Shirasawa, R | 1 |
| Jindal, SP; Lutz, T; Vestergaard, P | 1 |
| Cravey, RH; Garriott, JC; Lundberg, GD; Reynolds, PC; Shaw, RF | 1 |
| Fry, WA | 1 |
| Brewitt, H; Honegger, H | 1 |
| Kopanda, RT; Post, RM | 1 |
| Christie, JL | 1 |
| Kelder, D; Ross, SB | 1 |
| Kunze, H; Nahas, N; Traynor, JR; Wurl, M | 1 |
| Josephson, I; Sperelakis, N | 1 |
| Dearstyne, MR; Engstrom, TG; McMillan, DE | 1 |
| Goldman, JL; Roffman, JD | 1 |
| Eastly, T; Winek, CL | 1 |
| Cooper, M; Watson, RL | 1 |
| de Jong, RH | 1 |
| Schenck, NL | 1 |
| Campbell, CD; Campbell, JP; Pillsbury, HC; Prazma, TU; Warren, DW | 1 |
| Grant, AO; Lancaster, AR; Lastra, AA; Starmer, CF | 1 |
| Davies, DW; Moylan, SL; O'Sullivan, G | 1 |
| Shapiro, RS | 1 |
| Clague, J; Earis, JE; Graham, DR; Hay, JG; Nisar, M | 1 |
| Janak, PH; Keppel, G; Martinez, JL | 1 |
| Janak, PH; Martinez, JL; Riedel, CA; Weinberger, SB | 1 |
| Dunwiddie, TV; Smith, D | 1 |
| Guzman, NA; Hernandez, L; Hoebel, BG | 2 |
| Gantenberg, NS; Hageman, GR | 1 |
| Olsen, GD; Sandberg, JA | 1 |
| Nye, HE; Seidler, FJ; Slotkin, TA | 1 |
| Goldberg, SR; Marley, RJ; Witkin, JM | 2 |
| Koegler, SM; Seidler, FJ; Slotkin, TA; Spencer, JR | 1 |
| Rubin, E; Stewart, G; Thomas, AP | 1 |
| Albertson, TE; Derlet, RW; Tharratt, RS | 1 |
| Kirkpatrick, MB; Middleton, RM; Shah, A | 1 |
| Anderson-Brown, T; Seidler, FJ; Slotkin, TA | 1 |
| Carroll, ME; Gieske, D; Krattiger, KL; Sadoff, DA | 1 |
| Barnes, M; Blakeslee, DB; Carnel, SB; Oswald, SG | 1 |
| Anwer, MS; Engelking, LR; McConnell, J; Shuster, L; Sullivan, D | 1 |
| Nettleton, J; Wang, GK | 1 |
| Anderson, AB; Baronoski, R; Colecchi, C; DeWitt, TG | 1 |
| Webb, J | 1 |
| Gomes, PJ; Muers, MF; Pearson, SB; Teale, C | 1 |
| Altieri, MF; Greene, A; Hawk, WH; Hegenbarth, MA; O'Donnell, R; Ochsenschlager, DW | 1 |
| Gomi, Y; Inagaki, O; Kasuya, Y; Ono, K; Suzuki, N | 1 |
| Friedrichs, GS; Merrill, GF; Wei, HM | 1 |
| Doezema, D; Martin, JR; Tandberg, D; Umland, E | 1 |
| Muers, MF; Pearson, SB; Teale, C | 1 |
| Bragdon, R; Crabbe, LH; Ernst, AA; Link, R; Winsemius, DK | 1 |
| Furukawa, K; Kitamura, K; Yamanaka, K | 1 |
| Woolverton, WL; Zacny, JP | 1 |
| Collins, AC; de Fiebre, CM; Ruth, JA | 1 |
| Peris, J; Zahniser, NR | 1 |
| Desmond, PM; Dresner, ML; Kreder, KJ; Pliskin, MJ | 1 |
| Lucas, LF; Rigor, BM; Schurr, A; West, CA | 1 |
| Cunningham, MG; Gramlich, CA; Stripling, JS | 1 |
| Gomez, J; Rodriguez, A | 1 |
| el-Kholy, A | 1 |
| al Khalifa, S; Paulose, KO; Sharma, RK; Shenoy, P | 1 |
| Nierenberg, J; Post, RM; Szele, F; Weiss, SR; Woodward, R | 1 |
| Béderová, E; Pisková, L; Racanský, V | 1 |
| Wang, GK | 1 |
| Berger, JJ; Pyles, ST; Saga-Rumley, SA | 1 |
| Dworkin, SI; Goeders, NE; Smith, JE | 1 |
| Gilroy, G; Goodell, JA; Huntress, JD | 1 |
| Whittet, HB; Williams, HO; Wright, A | 1 |
| Marbach, JJ; Wallenstein, SL | 1 |
| Fung, KP; Lee, TY; Mei, WC; Tso, HS | 1 |
| Jonathan, DA; Violaris, NS | 1 |
| Appell, LH; Blythe, LL; Craig, AM; Slizeski, ML | 1 |
| Barbosa, I; Bateman, NT; Davidson, AC; Gray, B; Hamblin, AS; Kooner, JS; Stokes, TC | 1 |
| Elner, A; Hardebo, JE | 1 |
| Klatt, EC; Montgomery, S; Namiki, T; Noguchi, TT | 1 |
| Kobrinski, E; Saxon, M | 1 |
| de la Garza, R; Johanson, CE | 1 |
| Cooper, KR; Jones, JR; Pesko, LJ; Powell, KD; Sessler, CN; Vitaliti, JC | 1 |
| Russell, RD; Stripling, JS | 2 |
| Grouse, DS; Kittrelle, JP; Seybold, ME | 1 |
| Harper, RK; Lesse, H | 1 |
| Paton, DM | 4 |
| Bennett, A; Stockley, HL | 1 |
| Westfall, TC | 1 |
| Barthel, W; Glusa, E; Markwardt, F | 1 |
| Aledort, LM; Niemetz, J | 1 |
| Coubeils, JL; Pullman, B | 1 |
| Bohn, E; Kunze, H; Vogt, W | 1 |
| Deptalla, H; Wiegershausen, B | 1 |
| Daly, JW; Huang, M; Shimizu, H; Takenoshita, M | 1 |
| Bennett, A; Whitney, B | 1 |
| Cliff, GS | 1 |
| Eichberg, J; Hauser, G | 1 |
| Bone, RC; Davidson, TM; Nahum, AM | 1 |
| Büchi, J; Koller, RJ; Perlia, X | 1 |
| Leuenberger, PM | 1 |
| Papahadjopoulos, D | 2 |
| Barga, JL | 1 |
| Judit, BS | 1 |
| Quastel, JH; Shankaran, R | 1 |
| Kazama, K | 1 |
| Corssen, G | 1 |
| Langley, OK | 1 |
| Westfall, DP | 1 |
| Brummett, R; Comeau, M; Vernon, J | 1 |
| Morita, M; Nagata, M; Sugimoto, J | 1 |
| Smith, R | 1 |
| Brasted, M; Westfall, TC | 1 |
| Belt, WD; Benoit, PW | 1 |
| Hudgins, PM; Putney, JW | 1 |
| Bykov, NF; Semenova, DI | 1 |
| Geddes, IC | 1 |
| Buu-Hoi, NP; Chanh, PH; Phuong, VV; Pinhas, H; Tuyen, HV | 1 |
| Krenis, LJ; Liu, PL; Ngai, SH | 1 |
| Dure-Smith, P; Freundlich, IM | 1 |
| Nishi, K | 1 |
| Aberg, G | 1 |
| Cheong, DK; Gangarosa, LP | 1 |
| Montoya, RG | 1 |
| Priest, WC; Sabelli, HC | 1 |
| Pedersen, B | 1 |
| Jones, I; Orr, D | 1 |
| Andersen, NB | 1 |
| Nott, MW | 1 |
| af Ekenstam, B | 1 |
| Patel, MA | 1 |
| Danthine, A | 1 |
| Bennett, A; Fleshler, B | 1 |
| Bang, FB; Foard, MA | 1 |
| Redford, M; Schofield, B | 1 |
| Lishajko, F; Von EULER, US; Voneuler, US | 1 |
| Setnikar, I | 3 |
| Daniel, EE; Wolowyk, M | 1 |
| Eckert, T; Möbus, W | 1 |
| Steiner, L | 1 |
| Thomas, KB | 1 |
| Bentley, GA | 1 |
| Setnikar, I; Tirone, P | 1 |
| Magistretti, MJ; Setnikar, I; Tirone, P | 1 |
| Stripling, JS | 1 |
| Gross, JB; Hartigan, ML; Schaffer, DW | 1 |
| Bahar, M; Flecknell, P; Nunn, JF; Rosen, M | 1 |
| Bahar, M; Cole, G; Rosen, M; Vickers, MD | 1 |
| Schmidt, SH | 1 |
| Pert, A; Post, RM; Sass, W; Squillace, KM | 1 |
| Fischman, MW; Hatano, Y; Schuster, CR | 1 |
| Pert, A; Post, RM; Squillace, KM | 1 |
| Frewin, DB; Gerke, DC | 1 |
| Doggrell, SA; Vincent, L | 1 |
| Spratto, GR; Wiechman, BE; Wood, TE | 1 |
| Hendricks, C; Stripling, JS | 2 |
| Freeman, RW; Harbison, RD | 1 |
| Fukuda, S; Takeshita, H; Toda, N | 1 |
| Felkel, H; Feuereisl, R; Fiser, F; Polák, J; Tománek, A | 1 |
| Kilpatrick, WR; Opp, DR; Pryor, GJ | 1 |
| Jukofsky, D; Mulé, SJ; Verebey, K | 1 |
| Bonatz, E; Brewitt, H; Honegger, H | 1 |
| Covino, BG; Gissen, AJ; Gregus, J | 1 |
| Burstein, JL; Hoffman, RS; Hollander, JE; Nelson, LS; Quick, AM; Shih, RD | 1 |
| Noorily, AD; Noorily, SH; Otto, RA | 1 |
| Fan, P; Oz, M; Weight, FF; Zhang, L | 1 |
| Balster, RL; Compton, DM; Martin, BR; Woodward, JJ | 1 |
| Dai, HB; Morgan, JP; Nunez, BD; Ross, JN; Sellke, FW; Wang, SY | 1 |
| Obergfell, A; Starke, K; Szabo, B | 1 |
| Blackburn, PA; Butler, KH; Clark, MR; Hughes, MJ; Riker, RL | 1 |
| Ellis, EF; Hamm, RJ; Lyeth, BG; Muir, JK | 1 |
| Balster, RL; Graham, JH | 1 |
| Bank, DE; Borchert, BA; Klatzko, MD; Schilling, CG; Uden, DL | 1 |
| Chin, E; Ernst, AA; Gonzaba, WT; Marvez, E; Nick, TG; Wood, E | 1 |
| Ellis, EF; Muir, JK | 1 |
| Ernst, AA; Marvez-Valls, E; Nick, TG; Weiss, SJ | 1 |
| Robinson, SR; Simonik, DK; Smotherman, WP | 1 |
| Katz, JL; Newman, AH; Nowak, G; Witkin, JM | 1 |
| Chen, NH; Reith, ME | 1 |
| Andresen, MC; Brodwick, M; Yang, M | 1 |
| Chow, JM; Raster, JF | 1 |
| Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC | 1 |
| Martinez, JL; Phillips, MY; Rodriguez, SB; Rodriguez, WA | 1 |
| Artru, AA | 1 |
| Noorily, AD; Sakai, CS; Tarver, CP | 1 |
| Graamans, K; Huizing, EH; Ingels, KJ; Nijziel, MR | 1 |
| Book, RG | 1 |
| Chuang, DM; Dick, D; Margolis, RL; Post, RM; Weiss, SR | 1 |
| Murphy, JL | 1 |
| Browning, M; Dunwiddie, TV; Smith, DA | 1 |
| Titus, F | 1 |
| Hackenberg, D; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD | 1 |
| Bauman, JL; Hariman, RJ; Liu, D | 1 |
| Charters, A; Kendall, JM; McCabe, SE | 1 |
| Blanke, J; Paulus, HJ; Wolstein, J | 1 |
| Griffiths, MV; Kasemsuwan, L | 1 |
| Jyväkorpi, M | 1 |
| Birchall, M; Hern, J; Lennox, P; Lund, V | 1 |
| Miao, L; Morgan, JP; Qiu, Z | 1 |
| Bernards, CM | 1 |
| Falk, JL; Lau, CE; Siris, A | 1 |
| Tirelli, E; Witkin, JM | 1 |
| Dick, W; Jage, J; Kleemann, PP; Latorre, F; Otter, W | 1 |
| Marley, RJ; Saito, T; Shimosato, K; Watanabe, S | 1 |
| Chen, NH; Liao, HY; Pan, WH; Tsai, FY | 1 |
| Barat, SA; Turkall, RM | 1 |
| Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD | 1 |
| Artru, AA; Bernards, CM; Mautz, DS; Powers, KM | 1 |
| McKeever, J; Nathan, B | 1 |
| Chavoshan, B; Grayburn, PA; Hansen, J; Hillis, LD; Jacobsen, TN; Landau, C; Lange, RA; Snyder, RW; Victor, RG | 1 |
| Calverley, PM; Davies, L; Earis, JE; Mister, R; Pearson, MG; Spence, DP | 1 |
| Doyle, E; Russell, SC | 1 |
| Abdel-Rahman, MS; Barat, SA | 2 |
| Falk, JL; Lau, CE | 1 |
| Kallen, RG; Wang, GK; Wang, SY; Wright, SN | 1 |
| Bittencourt, AL; Takahashi, RN | 1 |
| Huang, L; Ishiguro, Y; Morgan, JP; Woolf, JH | 1 |
| Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD | 1 |
| Denkler, K | 1 |
| Katsura, M; Ohkuma, S; Shimosato, K; Watanabe, S | 1 |
| Gaillard, Y; Pepin, G | 1 |
| Friedman, MB | 1 |
| Zempsky, WT | 1 |
| Jeske, AH | 1 |
| Aldous, WK; Jensen, R; Sieck, BM | 1 |
| Chan, JY; Chan, SH; Chang, AY; Tsen, LY | 1 |
| Baird, TJ; Briscoe, RJ; Carl, KL; Gauvin, DV; Holloway, FA; Vallett, M; Vanecek, SA; Wasielewski, JA | 1 |
| Sleth, JC | 1 |
| De Giovanni, N; Fucci, N | 1 |
| Keyes, PD; Rizos, J; Tallon, JM | 1 |
| Aiello, L; Campanella, L; Colapicchioni, C; Tomassetti, M | 1 |
| Krnjević, K; Liu, PL; McArdle, JJ; Ren, J; Ye, JH | 1 |
| Hosemann, W | 1 |
| Boek, WM; Graamans, K; Huizing, EH; Merkus, FW; Romeijn, SG; Verhoef, JC | 1 |
| Arbique, D; Chavoshan, B; Mansour, Y; Victor, RG; Vongpatanasin, W | 1 |
| Erzouki, HK; Goldberg, SR; Schindler, CW | 1 |
| Meyer, DR | 1 |
| Antonaci, F; Broich, G; Costa, A; Granella, F; Nappi, G; Pucci, E; Sances, G | 1 |
| Ahmadi, A; Antonelli, PJ; Prevatt, A | 1 |
| Bayer, BM; Dunn, KL; Pellegrino, TC | 1 |
| D'Mello, K; Falk, JL; Lau, CE | 1 |
| Meijer van Putten, JB | 1 |
| Lesser, TH; O'Donnell, NP; Tripathi, A; White, S | 1 |
| Black, Y; Eichenbaum, HB; Green-Jordan, K; Kantak, KM; Valencia, E | 1 |
| Crandall, CG; Victor, RG; Vongpatanasin, W | 1 |
| Rockley, TJ; Smith, JC | 1 |
| Achar, S; Kundu, S | 1 |
| Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K | 1 |
| Markley, HG | 1 |
| Abel, MS; Dassow, MS; Li, J; Olinger, AB | 1 |
| Cox, B; Durieux, ME; Marcus, MA | 1 |
| Cara, DM; Neale, LJ; Norris, AM | 1 |
| VAN DONGEN, K | 1 |
| BEGUIN, M; FLEURY, C; FROMMEL, E; VON LEDEBUR, I | 1 |
| ADRIANI, J; ZEPERNICK, R | 2 |
| ABE, T; HINGSON, RA | 1 |
| NAKAI, Y; YAMAMOTO, K | 1 |
| HONJO, S; YAMADA, T | 1 |
| FURUYA, M; HOSOGAWA, A; KIMURA, S; KOBAYASHI, Y; NAKAZAWA, A | 1 |
| KAJIYAMA, T; MATANO, M; NAKAZAWA, Y; ODA, T; UENO, A | 1 |
| HOLMES, CM | 1 |
| CRUMP, FJ; PARKER, DE; RAHM, WE; STROTHER, WF | 1 |
| DODA, M; GYOERGY, L; MOLNAR, J; NADOR, K | 1 |
| VESSMAN, J | 1 |
| CONDOURIS, GA; SHAKALIS, A | 1 |
| ANDERSEN, NB; GRAVENSTEIN, JS | 1 |
| SCHAPIRO, H; WOODWARD, ER | 1 |
| DRAPER, MH; FRIEBEL, H; KARZEL, K | 1 |
| THORNTON, JA | 1 |
| HANSON, FE; WOLBARSHT, ML | 1 |
| SABETIAN, M | 1 |
| Ducharme, J; Matheson, K | 1 |
| Rebec, GV; Sun, W | 1 |
| Agulian, SK; Baldwin, RM; Bradberry, CW; Everill, B; Kocsis, JD; Tamagnan, GD; Tokuno, HA; Wilkes, S | 1 |
| Mastrogiannis, DS; O'Brien, WF | 1 |
| Chen, Y; Cox, B; Ke, Q; Leaf, A; Morgan, JP; Wang, GK; Wang, SY; Xiao, YF; Yang, Y | 1 |
| Black, YD; Eichenbaum, HB; Green-Jordan, K; Kantak, KM | 1 |
| Barbaro, A | 1 |
| Swant, J; Thompson, AM; Wagner, JJ | 1 |
| Arai, S; Dohi, T; Hamamoto, M; Irifune, M; Kawahara, M; Kihira, K; Kitayama, S; Morita, K | 1 |
| Dohi, T; Kitayama, T; Morioka, N; Morita, K; Song, L | 1 |
| Mizogami, M; Morishima, S; Muramatsu, I; Takakura, K | 1 |
| Benveniste, H; Du, C; Fowler, JS; Koretsky, AP; Volkow, ND; Yu, M | 1 |
| Black, YD; Di Pietro, NC; Kantak, KM | 1 |
| Hardiman, AM | 1 |
| Allsop, P; Jindal, M; Oates, J; Thevasagayam, M | 1 |
| Leelanukrom, R; Prapongsena, P; Techanivate, A; Terachinda, D | 1 |
| Atkins, AL; Kantak, KM; Mashhoon, Y | 1 |
| Bruhova, I; Tikhonov, DB; Zhorov, BS | 1 |
| Steiner, H; Willuhn, I | 1 |
| Dargan, PI; Hoffman, RS; Wood, DM | 1 |
| Bryant, SM; Kalimullah, EA | 1 |
| Guay, J | 1 |
| Gostic, T; Klemenc, S; Stefane, B | 1 |
| Jenkins, MG; Kelly, OJ; Little, C; McCarron, P; Murphy, D | 1 |
| Goodrich, CM; Janes, AC; Kantak, KM; Mashhoon, Y; Silverman, DN | 1 |
| Bonci, A; Hahn, J; Hopf, FW | 1 |
| Cadet-Taïrou, A; Evrard, I; Legleye, S | 1 |
| Kantak, KM; Mashhoon, Y; Wells, AM | 1 |
| Hooper, PL; Jackman, CS; Sheidow, TG; Yau, GL | 1 |
| Ben-Shahar, O; Ettenberg, A; Haber, ZM; Su, ZI; Waldroup, SA; Wenzel, JM | 1 |
| Fu, B; Sharp, H | 1 |
| Brager, AJ; Glass, JD; Prosser, RA; Stowie, AC | 1 |
| Boehnke, M; Flueckiger, F; Garweg, JG; Goldblum, D; Tappeiner, C | 1 |
| Brisotti, MF; Kantak, KM; Yager, LM | 1 |
| Bamford, IJ; Bamford, NS; Lemos, JC; Lewis, JS; Nitulescu, I; Phillips, PE; Posielski, NM; Storey, GP; Wang, W | 1 |
| Addy, NA; Behrens, S; Mason, GF; Solecki, W; Wang, J; Wickham, RJ; Zwerling, B | 1 |
| Alañón, F; Alañón, MA; Calero, B; Jiménez, JA; Noriega, A; Plaza, G | 1 |
| Bustillos, JO; Carvalho, DG; Carvalho, VM; Chasin, AA; Diaz, E; Fukushima, AR; Spinosa, Hde S | 1 |
| Baheri, T; Feizbakhsh, R; Rezazadeh, M; Seidi, S; Yamini, Y | 1 |
| Gonzalez, J; Hastedt, M; Pragst, F; Rubio, NC | 1 |
| Avershal, J; Bires, K; Rawls, SM; Seo, S; Tallarida, CS; Tallarida, RJ | 1 |
| Ferrão, MF; Marcelo, MC; Mariotti, KC; Ortiz, RS | 1 |
| de Bairros, AV; dos Santos, A; Lapachinske, SF; Okai, GG; Yonamine, M | 1 |
| Jansson, JR; Wildsmith, JA | 1 |
| Daldrup, T; Hartung, B; Mahler, H; Pawlik, E; Plässer, G | 1 |
| Augusti, R; De Carvalho, TC; Filgueiras, PR; França, HS; Merlo, BB; Ortiz, RS; Rodrigues, RR; Romão, W; Santos, H; Souza, LM; Tosato, F; Vaz, BG | 1 |
| Costa, HB; de Souza, LM; Filgueiras, PR; Merlo, BB; Poppi, RJ; Rodrigues, RR; Romão, W; Santos, H; Vaz, BG | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
| Anzanello, MJ; Ferrão, MF; Fogliatto, FS; Kahmann, A; Marcelo, MCA; Mariotti, KC; Ortiz, RS | 1 |
| Daldrup, T; Knuth, M; Pawlik, E; Temme, O | 1 |
| Jero, J; Luukkainen, V; Sinkkonen, ST | 1 |
| Barroso, M; Costa, S; Fonseca, S; Franco, J; Gameiro, R | 1 |
| Carpenter, JE; Kim, E; Koch, DD; Moran, TP; Morgan, BW; Murray, BP; Ritchie, JC; Salehi, M; Schindler, JM | 1 |
| Alonso, ALS; Andraus, M; Cordeiro, Q; Frajzinger, R; Laranjeira, R; Pires, L; Ribeiro, A; Ribeiro, M; Speierl, H; Trevizol, AP; Tsanaclis, L | 1 |
| Adinoff, B; Becker, JE; Brown, ES; Kandil, E; Kroener, S; Leonard, D; Price, JL; Shaw, M; Suris, A | 1 |
| Castro, ASB; Chagas, FO; da Silva, LHM; Hespanhol, MC; Maldaner, AO; Marinho, PA; Patrício, PR; Soares, TS | 1 |
| Gil-Miravet, I; Guarque-Chabrera, J; Melchor-Eixea, I; Miquel, M; Olucha-Bordonau, F | 1 |
| Arana, VA; Arango-Meriño, L; Granados-Reyes, J; Mancera-Barros, J; Quevedo-Castro, C; Sarmiento-Gutiérrez, ÁE | 1 |
| Browne, T; Cervantes, A; Logan, BK; Nelson, BN; Strathmann, FG | 1 |
| Arantes, LC; Caldas, ED; da Silva, CM | 1 |
| Dick, JE; Kong, EF; Krushinski, LE; Vannoy, KJ | 1 |
| Svensson, KG; Trulsson, M | 1 |
12 review(s) available for cocaine and lidocaine
| Article | Year |
|---|---|
Cocaine, kindling, and psychosis.
Topics: Amphetamine; Cocaine; Drug Tolerance; Electric Stimulation; Epilepsy, Temporal Lobe; Humans; Lidocaine; Limbic System; Models, Biological; Models, Neurological; Neurocognitive Disorders; Psychoses, Substance-Induced; Recurrence; Seizures; Stress, Psychological | 1976 |
Fatal consequences of local anesthesia: report of five cases and a review of the literature.
Topics: Adult; Anesthetics, Local; Child; Cocaine; Female; Forensic Medicine; Humans; Lidocaine; Male; Middle Aged; Pregnancy; Procaine; Tetracaine | 1976 |
Studies on the mechanism of action of local anesthetics with phospholipid model membranes.
Topics: Anesthetics, Local; Calcium; Cocaine; Dibucaine; Diffusion; Electric Conductivity; Lidocaine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Membrane Potentials; Membranes, Artificial; Models, Biological; Permeability; Phospholipids; Procaine; Sodium; Surface Properties; Tetracaine | 1972 |
[Symptomatic treatment of cluster headache].
Topics: Alkaloids; Analgesics; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Ergotamine; Humans; Lidocaine; Methoxyflurane; Narcotics; Oxygen; Sumatriptan; Vasoconstrictor Agents | 1995 |
A risk-benefit assessment of topical percutaneous local anaesthetics in children.
Topics: Administration, Cutaneous; Administration, Topical; Anaphylaxis; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Synergism; Epinephrine; Ethyl Chloride; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Narcotics; Ointments; Prilocaine; Risk Assessment; Skin Absorption; Tetracaine | 1997 |
Topical anesthesia.
Topics: Adult; Anesthetics, Combined; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Patient Selection; Prilocaine; Research Design; Suture Techniques; Tetracaine; Wounds and Injuries | 1998 |
Principles of office anesthesia: part II. Topical anesthesia.
Topics: Administration, Topical; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Cocaine; Drug Combinations; Epinephrine; Humans; Iontophoresis; Lidocaine; Physicians, Family; Tetracaine; Vasoconstrictor Agents | 2002 |
Topical agents in the treatment of cluster headache.
Topics: Administration, Intranasal; Administration, Topical; Capsaicin; Cluster Headache; Cocaine; Dihydroergotamine; Humans; Lidocaine; Oxazolidinones; Serotonin Receptor Agonists; Sumatriptan; Tryptamines; Vasoconstrictor Agents | 2003 |
Toxicity of local anaesthetics.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Etidocaine; Humans; Lidocaine; Mepivacaine; Nervous System; Procaine; Tetracaine | 2003 |
Management of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cocaine; Cocaine-Related Disorders; Humans; Lidocaine; Long QT Syndrome; Myocardium; Potassium Channels; Sodium Bicarbonate; Sodium Channels | 2009 |
Methemoglobinemia related to local anesthetics: a summary of 242 episodes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia; Anesthetics, Local; Benzocaine; Child; Child, Preschool; Cocaine; Female; Hemoglobins; Humans; Infant; Lidocaine; Male; Methemoglobinemia; Middle Aged; Pregnancy; Prilocaine; Tetracaine; Young Adult | 2009 |
The use of topical anaesthesia during repair of minor lacerations in Departments of Emergency Medicine: a literature review.
Topics: Administration, Topical; Anesthetics, Local; Cocaine; Drug Combinations; Epinephrine; Humans; Lacerations; Lidocaine; Tetracaine | 2009 |
37 trial(s) available for cocaine and lidocaine
| Article | Year |
|---|---|
Cocaine and lidocaine have similar psychological effects after intranasal application.
Topics: Administration, Intranasal; Adult; Cocaine; Emotions; Euphoria; Humans; Lidocaine; Male; Time Factors | 1979 |
Comparison of the vasoconstrictive and anesthetic effects of intranasally applied cocaine vs. xylometazoline/lidocaine solution.
Topics: Administration, Intranasal; Adult; Anesthesia, Local; Cocaine; Double-Blind Method; Humans; Imidazoles; Lidocaine; Nasal Decongestants; Nasal Mucosa | 1992 |
Topical anaesthesia of the larynx: cocaine or lignocaine?
Topics: Absorption; Adult; Aerosols; Aged; Aged, 80 and over; Anesthesia, Local; Blood Pressure; Cocaine; Cough; Double-Blind Method; Humans; Intermittent Positive-Pressure Ventilation; Intubation, Intratracheal; Larynx; Lidocaine; Middle Aged; Pulse; Time Factors | 1992 |
Comparison of three different methods used to achieve local anesthesia for fiberoptic bronchoscopy.
Topics: Aerosols; Anesthesia, Local; Bronchoscopy; Cocaine; Cough; Evaluation Studies as Topic; Fiber Optic Technology; Humans; Lidocaine; Patient Satisfaction; Respiratory Sounds | 1992 |
Topical nasal anesthesia for flexible bronchoscopy. A comparison of four methods in normal subjects and in patients undergoing transnasal bronchoscopy.
Topics: Administration, Intranasal; Adult; Anesthesia, Local; Anesthetics, Local; Bronchoscopy; Cocaine; Humans; Intubation, Gastrointestinal; Lidocaine; Male; Middle Aged; Nose; Phenylephrine | 1991 |
Treatment of radiation- and chemotherapy-induced stomatitis.
Topics: Administration, Topical; Cocaine; Diphenhydramine; Drug Combinations; Humans; Kaolin; Lidocaine; Mouth Mucosa; Pectins; Propiophenones; Stomatitis; Tongue | 1990 |
Local anesthesia in pediatric patients: topical TAC versus lidocaine.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Double-Blind Method; Drug Combinations; Emergencies; Epinephrine; Humans; Injections, Intradermal; Lidocaine; Patient Compliance; Randomized Controlled Trials as Topic; Tetracaine; Wounds and Injuries | 1990 |
Local anaesthesia for fibreoptic bronchoscopy: comparison between intratracheal cocaine and lignocaine.
Topics: Aged; Aged, 80 and over; Anesthesia, Endotracheal; Anesthesia, Local; Bronchoscopy; Cocaine; Double-Blind Method; Female; Fiber Optic Technology; Humans; Lidocaine; Male; Middle Aged | 1990 |
Comparison of tetracaine, adrenaline, and cocaine with cocaine alone for topical anesthesia.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinations; Epinephrine; Humans; Lidocaine; Randomized Controlled Trials as Topic; Tetracaine; Wounds, Penetrating | 1990 |
Cocaine and lidocaine as topical urethral anesthetics.
Topics: Anesthesia, Local; Anesthetics, Local; Cocaine; Cystoscopy; Double-Blind Method; Humans; Lidocaine; Male; Pain Measurement; Random Allocation; Urethra | 1989 |
An evaluation of topical anaesthesia for myringotomy.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Middle Aged; Middle Ear Ventilation; Pain Measurement; Prilocaine; Prospective Studies | 1988 |
Anaesthesia for laryngoscopy. A comparison of the cardiovascular effects of cocaine and lignocaine.
Topics: Aged; Anesthesia, Intravenous; Anesthesia, Local; Cardiovascular System; Cocaine; Heart; Heart Rate; Humans; Hypertension; Hypotension; Laryngoscopy; Lidocaine; Male; Propranolol; Tachycardia | 1968 |
A comparison of the subjective and cardiovascular effects of cocaine and lidocaine in humans.
Topics: Adult; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Emotions; Female; Heart Rate; Humans; Kinetics; Lidocaine; Male | 1983 |
Intranasal cocaine: dose relationships of psychological effects and plasma levels.
Topics: Administration, Intranasal; Adult; Cocaine; Dose-Response Relationship, Drug; Euphoria; Half-Life; Humans; Lidocaine; Male; Middle Aged; Psychological Tests; Sensation | 1982 |
Local anesthesia in minor lacerations: topical TAC vs lidocaine infiltration.
Topics: Administration, Topical; Adolescent; Anesthesia, Local; Child; Child, Preschool; Cocaine; Epinephrine; Humans; Infant; Lidocaine; Patient Acceptance of Health Care; Skin; Sutures; Tetracaine | 1980 |
Cocaine, lidocaine, tetracaine: which is best for topical nasal anesthesia?
Topics: Adult; Anesthesia, Local; Anesthetics, Local; Cocaine; Humans; Lidocaine; Male; Middle Aged; Nose; Pain Measurement; Pain Threshold; Tetracaine | 1995 |
Comparison of tetracaine-adrenaline-cocaine (TAC) with topical lidocaine-epinephrine (TLE): efficacy and cost.
Topics: Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cocaine; Cost Savings; Double-Blind Method; Drug Combinations; Drug Costs; Epinephrine; Humans; Lidocaine; Middle Aged; Pilot Projects; Prospective Studies; Tetracaine; Wounds and Injuries | 1995 |
Tetracaine, epinephrine (adrenalin), and cocaine (TAC) versus lidocaine, epinephrine, and tetracaine (LET) for anesthesia of lacerations in children.
Topics: Adolescent; Anesthesia, Local; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinations; Epinephrine; Female; Humans; Infant; Lidocaine; Male; Pain; Skin; Solutions; Sutures; Tetracaine; Wounds and Injuries | 1995 |
Lidocaine adrenaline tetracaine gel versus tetracaine adrenaline cocaine gel for topical anesthesia in linear scalp and facial lacerations in children aged 5 to 17 years.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinations; Emergency Medical Services; Epinephrine; Facial Injuries; Female; Humans; Lidocaine; Male; Pain Measurement; Scalp; Sutures; Tetracaine; Wounds, Penetrating | 1995 |
LAT (lidocaine-adrenaline-tetracaine) versus TAC (tetracaine-adrenaline-cocaine) for topical anesthesia in face and scalp lacerations.
Topics: Adult; Anesthetics, Local; Cocaine; Double-Blind Method; Drug Combinations; Drug Costs; Epinephrine; Facial Injuries; Female; Humans; Lidocaine; Male; Pain; Pain Measurement; Prospective Studies; Scalp; Sutures; Tetracaine; Wounds, Penetrating | 1995 |
A comparison of cocaine vs. lidocaine with oxymetazoline for use in nasal procedures.
Topics: Adult; Analysis of Variance; Cocaine; Double-Blind Method; Drug Therapy, Combination; Humans; Laser-Doppler Flowmetry; Lidocaine; Male; Nose; Oxymetazoline; Pain Measurement; Regional Blood Flow; Time Factors; Vasoconstriction | 1993 |
Comparison of topical anesthetics without cocaine to tetracaine-adrenaline-cocaine and lidocaine infiltration during repair of lacerations: bupivacaine-norepinephrine is an effective new topical anesthetic agent.
Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinations; Epinephrine; Female; Humans; Lidocaine; Male; Norepinephrine; Pain; Pain Measurement; Suture Techniques; Tetracaine; Wounds, Penetrating | 1996 |
Topical anaesthesia for children's lacerations: an acceptable approach?
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Combinations; Emergencies; Epinephrine; Humans; Lidocaine; Pain Measurement; Prospective Studies; Vasoconstrictor Agents; Wounds and Injuries | 1996 |
Lignocaine with adrenaline: is it as effective as cocaine in rhinological practice?
Topics: Adult; Airway Resistance; Anesthesia, Local; Anesthetics, Local; Blood Volume; Cocaine; Double-Blind Method; Endoscopy; Epinephrine; Humans; Lidocaine; Manometry; Nasal Decongestants; Nasal Mucosa; Nasal Obstruction; Nose; Pain; Pressure; Vasoconstrictor Agents | 1996 |
Local anaesthesia in flexible nasendoscopy. A comparison between cocaine and co-phenylcaine.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; Cost-Benefit Analysis; Drug Combinations; Endoscopy; Humans; Lidocaine; Middle Aged; Nose; Nose Diseases; Phenylephrine; Vasoconstrictor Agents | 1996 |
Cocaine or phenylephrine/lignocaine for nasal fibreoptic intubation?
Topics: Administration, Intranasal; Adult; Anesthesia, Local; Anesthetics, Local; Cocaine; Double-Blind Method; Endoscopy; Fiber Optic Technology; Humans; Intubation, Intratracheal; Lidocaine; Nose; Phenylephrine; Vasoconstrictor Agents | 1996 |
Comparison of topical anesthetics with lidocaine infiltration during laceration repair in children.
Topics: Adolescent; Analysis of Variance; Anesthetics, Combined; Anesthetics, Local; Chi-Square Distribution; Child; Child, Preschool; Cocaine; Double-Blind Method; Epinephrine; Female; Follow-Up Studies; Humans; Lidocaine; Male; Mepivacaine; Pain Measurement; Suture Techniques; Tetracaine; Treatment Outcome; Video Recording; Wounds, Penetrating | 1997 |
New non-cocaine-containing topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
Topics: Adolescent; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Epinephrine; Female; Humans; Infant; Lidocaine; Male; Pain; Phenylephrine; Prilocaine; Prospective Studies; Suture Techniques; Tetracaine; Wounds and Injuries | 1997 |
The effect of intranasal cocaine and lidocaine on nitroglycerin-induced attacks in cluster headache.
Topics: Administration, Intranasal; Adult; Anesthetics, Local; Cluster Headache; Cocaine; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Nitroglycerin; Pain Measurement; Statistics, Nonparametric; Vasodilator Agents | 2000 |
Mechanism of cocaine-induced hyperthermia in humans.
Topics: Adult; Blood Pressure; Body Temperature Regulation; Cocaine; Cross-Over Studies; Double-Blind Method; Esophagus; Female; Fever; Heart Rate; Humans; Lidocaine; Male; Sensory Thresholds; Skin; Sweating; Vasodilation | 2002 |
A comparison of cocaine and 'co-phenylcaine' local anaesthesia in flexible nasendoscopy.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Dosage Forms; Double-Blind Method; Female; Fiber Optic Technology; Humans; Laryngoscopy; Lidocaine; Male; Middle Aged; Nasal Decongestants; Otorhinolaryngologic Surgical Procedures; Phenylephrine | 2002 |
Pain during awake nasal intubation after topical cocaine or phenylephrine/lidocaine spray.
Topics: Administration, Intranasal; Adult; Aerosols; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Cross-Over Studies; Female; Humans; Intubation, Intratracheal; Lidocaine; Male; Pain; Pain Measurement; Phenylephrine | 2003 |
What is the best topical anesthetic for nasogastric insertion? A comparison of lidocaine gel, lidocaine spray, and atomized cocaine.
Topics: Administration, Intranasal; Administration, Topical; Anesthetics, Local; Cocaine; Cross-Over Studies; Double-Blind Method; Gels; Humans; Intubation, Gastrointestinal; Lidocaine; Nebulizers and Vaporizers; Pain Measurement; Patient Satisfaction | 2003 |
Does epinephrine infiltration in septoplasty make any difference? A double blind randomised controlled trial.
Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cocaine; Double-Blind Method; Drug Combinations; Epinephrine; History, Ancient; Humans; Hypertension; Intraoperative Complications; Lidocaine; Nasal Septum; Postoperative Hemorrhage; Rhinoplasty | 2007 |
Intravitreal injection anesthesia--comparison of different topical agents: a prospective randomized controlled trial.
Topics: Aged; Aged, 80 and over; Analgesia; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cocaine; Double-Blind Method; Female; Humans; Intravitreal Injections; Lidocaine; Macular Degeneration; Male; Pain Measurement; Prospective Studies; Ranibizumab; Tetracaine; Vitreous Body | 2011 |
[Comparison between topical anaesthesia with cocaine versus lidocaine plus adrenaline for outpatient laser dacryocystorhinostomy].
Topics: Adult; Aged; Ambulatory Care; Anesthesia, Local; Anesthetics, Local; Blood Loss, Surgical; Cocaine; Conscious Sedation; Dacryocystorhinostomy; Double-Blind Method; Epinephrine; Hemodynamics; Humans; Hypertension; Lacrimal Apparatus Diseases; Laser Therapy; Lidocaine; Middle Aged; Osteotomy; Pain Measurement; Postoperative Complications; Tachycardia; Vasoconstrictor Agents | 2014 |
The Efficacy of Lidocaine in Disrupting Cocaine Cue-Induced Memory Reconsolidation.
Topics: Adult; Animals; Cocaine; Cocaine-Related Disorders; Cues; Double-Blind Method; Drug-Seeking Behavior; Female; Humans; Lidocaine; Male; Memory Consolidation; Middle Aged; Treatment Outcome; Voltage-Gated Sodium Channel Blockers | 2020 |
308 other study(ies) available for cocaine and lidocaine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Molecular characteristics for solid-state limited solubility.
Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Local anesthesia of the face.
Topics: Administration, Topical; Anesthesia, Local; Cocaine; Epinephrine; Face; Humans; Injections, Subcutaneous; Lidocaine; Preanesthetic Medication | 1979 |
Changes in motor activity and acetylcholine turnover induced by lidocaine and cocaine in brain regions of rats.
Topics: Acetylcholine; Animals; Cerebral Cortex; Choline; Cocaine; Kinetics; Lidocaine; Male; Motor Activity; Rats; Stimulation, Chemical | 1979 |
Gas-liquid chromatographic-mass spectrometric determination of lidocaine in an illicit sample of cocaine.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Lidocaine; Pharmaceutical Preparations | 1979 |
Cocaine-related death.
Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Brain Edema; Cocaine; Ethanol; Female; Forensic Medicine; Humans; Intracranial Aneurysm; Lidocaine; Male; Morphine; Nortriptyline; Phenmetrazine; Substance-Related Disorders; Suicide; Tissue Distribution | 1977 |
Techniques of topical anesthesia for bronchoscopy.
Topics: Anesthesia, Local; Bronchoscopy; Cocaine; Humans; Lidocaine; Preanesthetic Medication; Tetracaine | 1978 |
[The influence of local anesthetics on corneal epithelium. A scanning electron microscopic study (author's transl)].
Topics: Anesthetics, Local; Animals; Cocaine; Cornea; Corneal Diseases; Epithelium; Lidocaine; Microscopy, Electron, Scanning; Propoxycaine; Rabbits; Tonometry, Ocular | 1978 |
Active transport of 3H-bretylium in the rat vas deferens in vitro.
Topics: Aminobenzoates; Amphetamine; Anesthetics, Local; Animals; Biological Transport, Active; Bretylium Compounds; Chlorides; Cocaine; Desipramine; Hydroxybenzoate Ethers; Hydroxydopamines; Imipramine; Lidocaine; Male; meta-Aminobenzoates; Ouabain; Rats; Reserpine; Sodium; Sympathetic Nervous System; Temperature; Vas Deferens | 1976 |
Effects of local anaesthetics on phospholipases.
Topics: Anesthetics, Local; Calcium; Chlorpromazine; Cocaine; Dibucaine; Humans; Kinetics; Lidocaine; Male; Phospholipases; Procaine; Semen; Snake Venoms; Tetracaine | 1976 |
Local anesthetic blockade of Ca2+ -mediated action potentials in cardiac muscle.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Chick Embryo; Cocaine; Heart; In Vitro Techniques; Lidocaine; Phenytoin; Procaine; Tetrodotoxin | 1976 |
Some effects of local anesthetics on schedule-controlled behavior.
Topics: Amphetamine; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Columbidae; Conditioning, Operant; Feeding Behavior; Injections, Intramuscular; Lidocaine; Male; Mepivacaine; Procaine; Reinforcement Schedule | 1975 |
Indirect laryngoscopy.
Topics: Anesthesia, Intravenous; Anesthesia, Local; Cocaine; History, 19th Century; History, 20th Century; Humans; Laryngeal Neoplasms; Laryngoscopy; Lidocaine; Preanesthetic Medication | 1975 |
Cocaine identification.
Topics: Chromatography, Thin Layer; Cocaine; False Positive Reactions; Lidocaine; Methods | 1975 |
An improved regional anesthetic technique for peroral endoscopy.
Topics: Anesthesia, Conduction; Bronchoscopy; Cocaine; Humans; Lidocaine | 1975 |
Biotransformation of local anesthetics: General concepts.
Topics: Anesthetics, Local; Animals; Biotransformation; Cocaine; Humans; Lidocaine; Mepivacaine; Prilocaine; Procainamide; Procaine | 1975 |
The case for cocaine.
Topics: Anesthetics, Local; Cocaine; Humans; Lidocaine | 1976 |
Which local anaesthetic?
Topics: Administration, Topical; Anesthesia, Conduction; Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Local; Bupivacaine; Cocaine; Humans; Lidocaine; Nerve Block; Prilocaine | 1976 |
Cardiac instability amplified by use-dependent Na channel blockade.
Topics: Animals; Cocaine; Heart; Lidocaine; Rabbits; Sodium Channels; Time Factors | 1992 |
Paroxysmal sneezing in children: two new cases.
Topics: Administration, Intranasal; Beclomethasone; Child; Cocaine; Female; Humans; Lidocaine; Prednisone; Rhinitis, Allergic, Perennial; Sneezing | 1992 |
Cocaine enhances retention of avoidance conditioning in rats.
Topics: Animals; Avoidance Learning; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Lidocaine; Male; Memory; Rats; Rats, Inbred Strains | 1992 |
Cocaine enhances one-way avoidance responding in mice.
Topics: Animals; Avoidance Learning; Cocaine; Lidocaine; Male; Mice | 1992 |
Cocaine and other local anesthetics block hippocampal long-term potentiation.
Topics: Anesthetics, Local; Animals; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Lidocaine; Procaine; Pyramidal Tracts; Rats | 1992 |
Differential dopaminergic potency of cocaine, procaine and lidocaine infused locally in the nucleus accumbens in vivo with calibration by capillary electrophoresis in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Cocaine; Dopamine; Dopamine Agents; Electrophoresis; Homovanillic Acid; Injections; Lidocaine; Nucleus Accumbens; Procaine; Rats | 1990 |
Cocaine depresses cardiac sympathetic efferent activity in anesthetized dogs.
Topics: Animals; Blood Pressure; Cocaine; Depression, Chemical; Dogs; Female; Heart; Heart Rate; Lidocaine; Male; Neurons, Efferent; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1991 |
Cocaine and metabolite concentrations in the fetal guinea pig after chronic maternal cocaine administration.
Topics: Amniotic Fluid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Lidocaine; Maternal-Fetal Exchange; Pregnancy | 1992 |
Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs.
Topics: Abnormalities, Drug-Induced; Aging; Animals; Cocaine; Female; Heart; Lidocaine; Myocardium; Nerve Endings; Norepinephrine; Pregnancy; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synapses; Yohimbine | 1991 |
A pharmacogenetic evaluation of the role of local anesthetic actions in the cocaine kindling process.
Topics: Animals; Cocaine; Convulsants; Disease Susceptibility; Drug Tolerance; Kindling, Neurologic; Lidocaine; Male; Mice; Mice, Inbred Strains | 1991 |
Ischemia contributes to adverse effects of cocaine on brain development: suppression of ornithine decarboxylase activity in neonatal rat.
Topics: Animals; Brain; Brain Ischemia; Cocaine; Injections, Intraventricular; Injections, Subcutaneous; Lidocaine; Ornithine Decarboxylase; Rats; Rats, Inbred Strains | 1991 |
Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion.
Topics: Animals; Cocaine; Dialysis; Diffusion; Dopamine; Electrophoresis; Lidocaine; Microchemistry; Nucleus Accumbens; Procaine; Rats | 1991 |
Inhibition by cocaine of excitation-contraction coupling in isolated cardiomyocytes.
Topics: Animals; Calcium; Cell Separation; Cocaine; Dose-Response Relationship, Drug; Electric Conductivity; Heart; Lidocaine; Membrane Potentials; Myocardial Contraction; Myocardium; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Sodium Channels; Sympathetic Nervous System; Tetrodotoxin; Verapamil | 1991 |
Lack of a genetic correlation between the convulsant and epileptogenic effects of cocaine and lidocaine.
Topics: Animals; Cocaine; Convulsants; Epilepsy; Lidocaine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains | 1990 |
Lidocaine potentiation of cocaine toxicity.
Topics: Animals; Cocaine; Drug Synergism; Lidocaine; Male; Rats; Rats, Inbred Strains; Seizures | 1991 |
Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions.
Topics: Aging; Animals; Brain; Cell Division; Cocaine; DNA; Female; Leucine; Lidocaine; Methoxamine; Nerve Tissue Proteins; Phenoxybenzamine; Pregnancy; Rats; Rats, Inbred Strains; Thymidine | 1990 |
Cocaine-base smoking in rhesus monkeys: reinforcing and physiological effects.
Topics: Animals; Blood Pressure; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Humans; Lidocaine; Macaca mulatta; Male; Reinforcement, Psychology; Smoking; Substance-Related Disorders | 1990 |
Cocaine and lidocaine interfere with epinephrine-induced changes in intracellular calcium concentration and glucose efflux from rat hepatocytes.
Topics: Animals; Bucladesine; Calcium; Cocaine; Cyclic AMP; Epinephrine; Glucose; Glycogen; Lidocaine; Liver; Rats | 1990 |
pH-dependent binding of local anesthetics in single batrachotoxin-activated Na+ channels. Cocaine vs. quaternary compounds.
Topics: Anesthetics, Local; Animals; Batrachotoxins; Binding Sites; Cocaine; Hydrogen-Ion Concentration; Kinetics; Lidocaine; Lipid Bilayers; Models, Biological; Muscles; Naphthalenes; Phosphatidylcholines; Phosphatidylethanolamines; Protein Binding; Pyrrolidinones; Rabbits; Sodium Channels | 1990 |
Local anaesthesia for fibreoptic bronchoscopy--where are we now?
Topics: Anesthesia, Local; Bronchoscopy; Cocaine; Fiber Optic Technology; Humans; Lidocaine | 1990 |
Comparison of topical tetracaine, adrenaline, and cocaine anesthesia with lidocaine infiltration for repair of lacerations in children.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Combinations; Epinephrine; Female; Humans; Infant; Lidocaine; Male; Patient Acceptance of Health Care; Prospective Studies; Surgical Wound Dehiscence; Tetracaine; Wound Infection; Wounds, Penetrating | 1990 |
Propranolol blocks cocaine-induced potentiation of the contraction in the smooth muscle of the rat vas deferens.
Topics: Animals; Cocaine; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Propranolol; Rats; Rats, Inbred Strains; Sotalol; Vas Deferens | 1990 |
Coronary vasodilation caused by intravenous cocaine in the anesthetized beagle.
Topics: Anesthesia; Animals; Cocaine; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Female; Hemodynamics; Injections, Intravenous; Lidocaine; Male; Vasodilation | 1990 |
The effect of local anesthetics on bacterial proliferation: TAC versus lidocaine.
Topics: Administration, Topical; Anesthetics, Local; Animals; Bacteria; Cocaine; Drug Combinations; Epinephrine; Lidocaine; Male; Staphylococcus aureus; Swine; Tetracaine; Wound Infection; Wounds, Penetrating | 1990 |
Local anaesthesia for fibreoptic bronchoscopy.
Topics: Anesthesia, Local; Bronchoscopy; Cocaine; Fiber Optic Technology; Humans; Lidocaine | 1990 |
The different mechanisms of action of nicorandil and adenosine triphosphate on potassium channels of circular smooth muscle of the guinea-pig small intestine.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Apamin; Cocaine; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Ion Channels; Lidocaine; Male; Membrane Potentials; Muscle, Smooth; Niacinamide; Nicorandil; Procaine; Vasodilator Agents | 1985 |
Discriminative stimulus properties of local anesthetics in d-amphetamine- and pentobarbital-trained pigeons.
Topics: Animals; Cocaine; Columbidae; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Generalization, Stimulus; Lidocaine; Pentobarbital; Procaine | 1989 |
Differential sensitivity of long-sleep and short-sleep mice to high doses of cocaine.
Topics: Animals; Body Temperature; Cocaine; Dopamine; Dose-Response Relationship, Drug; Female; Heart Rate; Lidocaine; Male; Mice; Mice, Inbred Strains; Motor Activity; Norepinephrine; Reflex, Startle; Respiration; Seizures; Serotonin; Sleep; Species Specificity | 1989 |
Persistent augmented dopamine release after acute cocaine requires dopamine receptor activation.
Topics: Animals; Apomorphine; Benzazepines; Cocaine; Dopamine; Dopamine Antagonists; Fluphenazine; Lidocaine; Male; Mazindol; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride | 1989 |
Protection against cerebral hypoxia by local anesthetics: a study using brain slices.
Topics: Action Potentials; Anesthetics, Local; Animals; Cocaine; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Lidocaine; Male; Microtomy; Procaine; Rats; Rats, Inbred Strains | 1989 |
Effect of cocaine and lidocaine on the development of kindled seizures.
Topics: Animals; Cocaine; Electric Stimulation; Kindling, Neurologic; Lidocaine; Male; Rats; Seizures | 1989 |
An evaluation of the results of a drug sample analysis.
Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders | 1989 |
Manipulation of the fractured nose using topical local anaesthesia.
Topics: Administration, Topical; Adolescent; Adult; Anesthesia, Local; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Manipulation, Orthopedic; Nasal Bone; Prilocaine; Skull Fractures | 1989 |
Maxillary antral lavage--infiltration and surface anaesthesia compared.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anesthesia, Local; Cocaine; Epinephrine; Female; Humans; Injections; Lidocaine; Male; Maxillary Sinus; Middle Aged; Patient Acceptance of Health Care; Prospective Studies; Sinusitis; Therapeutic Irrigation; Time Factors | 1989 |
Chronic carbamazepine inhibits the development of local anesthetic seizures kindled by cocaine and lidocaine.
Topics: Anesthetics; Animals; Anticonvulsants; Carbamazepine; Cocaine; Dose-Response Relationship, Drug; Kindling, Neurologic; Lidocaine; Male; Rats; Rats, Inbred Strains | 1989 |
The influence of local anesthetics on the gel-liquid crystal phase transition in model dipalmitoylphosphatidylcholine membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Anesthetics, Local; Cocaine; Dibucaine; Electron Spin Resonance Spectroscopy; Gels; Lidocaine; Lipid Bilayers; Microscopy, Polarization; Physical Phenomena; Physics; Piperidines; Tetracaine | 1988 |
Cocaine-induced closures of single batrachotoxin-activated Na+ channels in planar lipid bilayers.
Topics: Anesthetics, Local; Animals; Batrachotoxins; Binding Sites; Bupivacaine; Cocaine; Dose-Response Relationship, Drug; Electrophysiology; Lidocaine; Lipid Bilayers; Muscles; Rabbits; Sodium Channels | 1988 |
Does topical anesthesia of the sphenopalatine ganglion with cocaine or lidocaine relieve low back pain?
Topics: Administration, Topical; Adult; Aged; Back Pain; Cocaine; Double-Blind Method; Drug Evaluation; Female; Ganglionic Blockers; Humans; Lidocaine; Male; Middle Aged | 1986 |
Neuropharmacological assessment of cocaine self-administration into the medial prefrontal cortex.
Topics: Amphetamine; Animals; Cerebral Cortex; Cocaine; Dose-Response Relationship, Drug; Injections; Lidocaine; Male; Neurotransmitter Agents; Rats; Rats, Inbred F344; Self Administration; Time Factors | 1986 |
Reducing cocaine solution use by promoting the use of a lidocaine-phenylephrine solution.
Topics: Anesthesia; Cocaine; Drug Combinations; Drug Utilization; Intubation, Intratracheal; Lidocaine; Pharmacy Service, Hospital; Phenylephrine; Solutions | 1988 |
Analgesic, mood, and hemodynamic effects of intranasal cocaine and lidocaine in chronic facial pain of deafferentation and myofascial origin.
Topics: Administration, Intranasal; Adult; Affect; Aged; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Facial Neuralgia; Facial Pain; Female; Hemodynamics; Humans; Lidocaine; Middle Aged; Myofascial Pain Syndromes; Random Allocation | 1988 |
Incidence and treatment of postoperative sore throat and hoarseness following endotracheal intubation.
Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Cocaine; Female; Hoarseness; Humans; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Nebulizers and Vaporizers; Pharyngitis; Retrospective Studies; Sex Factors | 1988 |
Comparison of cocaine and lignocaine as intranasal local anaesthetics.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Cocaine; Female; Humans; Lidocaine; Male; Maxillary Sinus; Middle Aged | 1988 |
Evaluation of the potential for interference by dimethyl sulfoxide (DMSO) in drug detection in racing animals.
Topics: Acepromazine; Animals; Apomorphine; Caffeine; Chromatography, Thin Layer; Clonixin; Cocaine; Dimethyl Sulfoxide; Drug Interactions; Female; Furosemide; Horses; Lidocaine; Pharmaceutical Preparations; Phenylbutazone | 1987 |
The influence of topical anaesthetic agent at bronchoalveolar lavage upon cellular yield and identification and upon macrophage function.
Topics: Bronchi; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cell Count; Cocaine; Humans; Lidocaine; Macrophages; Pulmonary Alveoli; Sarcoidosis; Therapeutic Irrigation | 1986 |
Nerves and vessels in the pterygopalatine fossa and symptoms of cluster headache.
Topics: Adult; Aged; Cluster Headache; Cocaine; Drug Evaluation; Female; Humans; Lidocaine; Male; Middle Aged; Parasympathetic Nervous System; Sympathetic Nervous System; Vascular Headaches | 1987 |
Misrepresentation of stimulant street drugs: a decade of experience in an analysis program.
Topics: Adult; Amphetamines; Caffeine; Cocaine; Ephedrine; Humans; Illicit Drugs; Lidocaine | 1986 |
Two types of spontaneous contractions in rat myocardium and their possible relation to different Ca release processes.
Topics: Animals; Calcium; Cocaine; Dantrolene; In Vitro Techniques; Lidocaine; Myocardial Contraction; Myocardium; Proadifen; Rats; Rats, Inbred Strains | 1986 |
Discriminative stimulus properties of cocaine in pigeons.
Topics: Alkaloids; Animals; Apomorphine; Cocaine; Columbidae; Dextroamphetamine; Discrimination, Psychological; Dopamine; Lidocaine; Nicotine; Oxazepam; Pentobarbital; Procaine; Psychotropic Drugs; Reinforcement Schedule | 1985 |
Comparison of 4% lidocaine/0.5% phenylephrine with 5% cocaine: which dilates the nasal passage better?
Topics: Adult; Cocaine; Dilatation; Female; Humans; Lidocaine; Male; Nasal Mucosa; Peak Expiratory Flow Rate; Phenylephrine; Vital Capacity | 1986 |
Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression.
Topics: Amphetamine; Anesthetics, Local; Animals; Biogenic Amines; Cocaine; Drug Interactions; Haloperidol; Kindling, Neurologic; Lidocaine; Male; Metergoline; Prazosin; Propranolol; Rats; Seizures; Yohimbine | 1985 |
Cluster headache. Local anesthetic abortive agents.
Topics: Adult; Aged; Cluster Headache; Cocaine; Female; Humans; Lidocaine; Male; Middle Aged; Vascular Headaches | 1985 |
Frequency-related, bidirectional limbic responses to cocaine: comparisons with amphetamine and lidocaine.
Topics: Amygdala; Animals; Cats; Cell Membrane; Cocaine; Dextroamphetamine; Electric Stimulation; Evoked Potentials; Female; Hippocampus; Lidocaine; Limbic System; Septum Pellucidum | 1985 |
Effect of cocaine and pentylenetetrazol on cortical kindling.
Topics: Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Infusions, Parenteral; Kindling, Neurologic; Lidocaine; Male; Pentylenetetrazole; Postural Balance; Rats; Seizures | 1985 |
Evidence for carrier-mediated efflux of noradrenaline from the axoplasm of adrenergic nerves in rabbit atria.
Topics: Animals; Axons; Cell Membrane; Cocaine; Desipramine; Heart Atria; In Vitro Techniques; Isoproterenol; Lidocaine; Metaraminol; Norepinephrine; Normetanephrine; Rabbits; Reserpine; Sympathetic Nervous System; Time Factors; Tritium; Tyramine | 1973 |
Electrically induced contractions of guinea-pig isolated ileum resistant to tetrodotoxin.
Topics: Acetylcholine; Animals; Cocaine; Cold Temperature; Drug Resistance; Electric Stimulation; Guinea Pigs; Histamine H1 Antagonists; Hypoxia; Ileum; In Vitro Techniques; Lidocaine; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Phloretin; Potassium Chloride; Prostaglandins; Scopolamine; Serotonin Antagonists; Tetrodotoxin | 1973 |
Effect of nicotine and other drugs on the release of 3H-norepinephrine and 3H-dopamine from rat brain slices.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Culture Media; Deamination; Dopamine; Edetic Acid; Hexamethonium Compounds; Hypothalamus; In Vitro Techniques; Lidocaine; Methacholine Compounds; Methylation; Morphine; Nicotine; Norepinephrine; Peripheral Nerves; Phenoxybenzamine; Rats; Tritium | 1974 |
[Changes in the serotonin and histamine content of blood platelets due to the effect of local anesthetics].
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Blood Platelets; Cocaine; Histamine; Lidocaine; Procaine; Rabbits; Serotonin; Tetracaine | 1966 |
Dissociation of platelet aggregation from clot retraction, potassium loss, and adenosine triphosphatase activity.
Topics: 4-Aminobenzoic Acid; Adenosine Triphosphatases; Anesthetics, Local; Blood Coagulation; Blood Platelets; Cocaine; Dibucaine; Lidocaine; Potassium; Procaine; Tetracaine; Thrombin | 1968 |
Quantum-mechanical study of the conformational properties of drugs with local anesthetic action.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Chemical Phenomena; Chemistry; Cocaine; Lidocaine; Procaine; Quantum Theory; Quaternary Ammonium Compounds; Receptors, Drug; Structure-Activity Relationship | 1972 |
Effects of local anaesthetics on prostaglandin biosynthesis in vitro.
Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Animals; Benzocaine; Calcium; Carbon Radioisotopes; Cattle; Chlorpromazine; Chromatography, Thin Layer; Cocaine; Dibucaine; Edetic Acid; Kinetics; Lidocaine; Linoleic Acids; Male; Mepivacaine; Oleic Acids; Phosphatidylethanolamines; Phospholipases; Procaine; Prostaglandins; Seminal Vesicles; Sheep; Snakes; Species Specificity; Tetracaine; Triglycerides | 1974 |
[Influence of local anesthetics on the excitation activity of bradykinin on smooth muscle. II. Potentiation of bradykinin contraction in the guinea pig ileum].
Topics: Acetylcholine; Aminocaproates; Anesthetics, Local; Angiotensin II; Animals; Bradykinin; Caffeine; Cocaine; Drug Synergism; Eledoisin; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Procaine; Serotonin; Tetracaine | 1969 |
Accumulation of adenosine 3',5'-monophosphate in brain slices: interaction of local anaesthetics and depolarizing agents.
Topics: Adenosine; Anesthetics, Local; Animals; Brain; Carbon Isotopes; Cocaine; Cyclic AMP; Dibucaine; Drug Interactions; Guinea Pigs; Histamine; In Vitro Techniques; Lidocaine; Neuromuscular Depolarizing Agents; Norepinephrine; Ouabain; Potassium Chloride; Procaine; Tetracaine | 1973 |
A pharmacological investigation of human isolated stomach.
Topics: Acetylcholine; Cocaine; Epinephrine; Ergoloid Mesylates; Ethanolamines; Guanethidine; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Isoproterenol; Lidocaine; Methysergide; Neostigmine; Nicotine; Norepinephrine; Pentolinium Tartrate; Physostigmine; Piperazines; Potassium Chloride; Scopolamine; Serotonin; Stomach; Sympathomimetics | 1966 |
Drug-induced rhythmicity in smooth muscle.
Topics: Animals; Cocaine; Guinea Pigs; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Procaine; Rats; Vas Deferens | 1968 |
Stimulation by local anesthetics of the metabolism of acidic phospholipids in the rat pineal gland.
Topics: Anesthetics, Local; Animals; Chromatography, Thin Layer; Cocaine; Cytidine; Dibucaine; Dose-Response Relationship, Drug; Lidocaine; Phosphatidic Acids; Phosphatidylinositols; Phospholipids; Phosphorus Radioisotopes; Pineal Gland; Procaine; Propranolol; Rats; Tetracaine; Tritium | 1974 |
Flexible fiberoptic laryngobronchoscopy.
Topics: Atropine; Biopsy; Bronchoscopy; Carcinoma, Squamous Cell; Cocaine; Epinephrine; Fiber Optic Technology; Foreign Bodies; Humans; Intubation, Intratracheal; Laryngoscopy; Lidocaine; Nasopharyngeal Neoplasms; Neck; Oxygen Inhalation Therapy; Pneumonia; Respiratory Tract Diseases; Tetracaine | 1974 |
[Relationship between chemical structure, physio-chemical properties, chemical reactivity and effect of various local anesthetics with position isomerism. 31. 1].
Topics: Acetanilides; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, Local; Animals; Anthelmintics; Benzocaine; Binding Sites; Blood Pressure; Chemical Phenomena; Chemistry; Cocaine; Diphenhydramine; Ethylamines; Hydroxides; Isomerism; Lethal Dose 50; Lidocaine; Mice; Procaine; Propylamines; Quaternary Ammonium Compounds; Rabbits; Rats; Structure-Activity Relationship; Sulfanilamides | 1974 |
[Ultrastructure of corneal epithelium after topical anesthesia].
Topics: Anesthesia, Local; Anesthetics, Local; Animals; Benzoates; Cell Membrane; Cocaine; Cornea; Cytoplasm; Epithelial Cells; Lidocaine; Male; Microscopy, Electron, Scanning; Rats; Tetracaine | 1973 |
How to treat nosebleed.
Topics: Age Factors; Anticoagulants; Blood Coagulation Disorders; Cocaine; Craniocerebral Trauma; Drug Combinations; Epinephrine; Epistaxis; Humans; Hypertension; Infections; Lidocaine; Lung Diseases; Methods; Palatal Expansion Technique; Paranasal Sinuses; Physical Examination; Tampons, Surgical | 1973 |
[Iatrogenic lesion in ophthalmologic anesthesia].
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Local; Anesthetics; Anesthetics, Local; Atropine; Blindness; Cataract Extraction; Cocaine; Depression, Chemical; Drug Hypersensitivity; Eye Diseases; Glaucoma; Heart Rate; Humans; Iatrogenic Disease; Intraocular Pressure; Lidocaine; Male; Middle Aged; Procaine; Tetracaine; Tonometry, Ocular | 1972 |
Effects of anesthetics on sodium uptake into rat brain cortex in vitro.
Topics: Amobarbital; Anesthetics, Local; Animals; Brain Chemistry; Calcium; Cerebral Cortex; Cocaine; Dinitrophenols; Glucose; In Vitro Techniques; Lidocaine; Manometry; Oxygen Consumption; Potassium; Potassium Chloride; Protoveratrines; Rats; Sodium; Sodium Isotopes; Tetrodotoxin; Thiopental; Water | 1972 |
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit].
Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine | 1972 |
Toxic effects of local anaesthetics on human respiratory epithelium.
Topics: Anesthetics, Local; Bronchi; Cilia; Cocaine; Dibucaine; Epithelium; Humans; In Vitro Techniques; Lidocaine; Procaine; Respiratory System; Tetracaine; Time Factors; Trachea | 1973 |
Local anaesthetics and nodal polyanions in peripheral nerve.
Topics: Anesthetics, Local; Animals; Binding Sites; Binding, Competitive; Cations, Divalent; Cations, Monovalent; Cocaine; Female; Histocytochemistry; Lidocaine; Male; Neural Conduction; Procaine; Ranvier's Nodes; Rats; Sciatic Nerve; Tetracaine; Tetraethylammonium Compounds | 1973 |
Antagonism by protriptyline and desipramine of the response of the vas deferens of the rat to norepinephrine, acetylcholine and potassium.
Topics: Acetylcholine; Animals; Cocaine; Desipramine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Inflammation; Lidocaine; Male; Norepinephrine; Potassium; Propylamines; Rats; Vas Deferens | 1973 |
Local anesthesia of the ear by iontophoresis.
Topics: Adult; Anesthesia, Local; Animals; Audiometry; Child; Child, Preschool; Cocaine; Cochlea; Cochlear Nerve; Ear; Ear, External; Ear, Middle; Electrodes, Implanted; Electrophysiology; Female; Guinea Pigs; Humans; Iontophoresis; Lidocaine; Male; Methods; Myringoplasty; Tympanic Membrane | 1973 |
Mechanism of efflux of noradrenaline from adrenergic nerves in rabbit atria.
Topics: Animals; Cocaine; Desipramine; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male; Metaraminol; Norepinephrine; Normetanephrine; Pargyline; Potassium; Premedication; Rabbits; Reserpine; Sodium; Sympathetic Nervous System; Temperature; Time Factors; Tritium; Tyramine | 1973 |
Comparative studies on the pharmacological actions of anti-arrhythmics in isolated guinea-pig atria.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Benzyl Compounds; Cocaine; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Lidocaine; Male; Methyl Ethers; Phenytoin; Piperazines; Procainamide; Propranolol; Quinidine | 1973 |
Managing epistaxis.
Topics: Anesthesia, Local; Carotid Artery, External; Cocaine; Epistaxis; Ethmoid Sinus; Hemostasis; Humans; Lidocaine; Ligation; Maxillary Artery; Methods; Nasal Mucosa; Nose; Surgical Instruments; Tampons, Surgical | 1974 |
Specificity of blockade of the nicotine-induced release of 3H-norepinephrine from adrenergic neurons of the guinea-pig heart by various pharmacological agents.
Topics: Aminophylline; Animals; Bretylium Compounds; Cocaine; Colchicine; Guinea Pigs; Heart; Hexamethonium Compounds; In Vitro Techniques; Lidocaine; Morphine; Myocardium; Neurons; Nicotine; Norepinephrine; Perfusion; Potassium Chloride; Prostaglandins; Stimulation, Chemical; Tritium; Tyramine | 1974 |
Some effects of local anesthetic agents on skeletal muscle.
Topics: Anesthesia, Local; Anesthetics; Animals; Bupivacaine; Cocaine; Lidocaine; Male; Mepivacaine; Muscles; Prilocaine; Procaine; Rats | 1972 |
Distribution of local anesthetics and the intracellular pH in vascular smooth muscle.
Topics: Anesthetics, Local; Animals; Aorta; Binding Sites; Calcium; Carbon Isotopes; Cocaine; Extracellular Space; Hydrogen-Ion Concentration; In Vitro Techniques; Ketones; Kinetics; Lidocaine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxazoles; Potassium; Procaine; Rabbits; Structure-Activity Relationship; Tetracaine | 1972 |
[Effect of local anesthetic substances on the reparative regneration of corneal epithelium].
Topics: Anesthetics, Local; Animals; Cocaine; Cornea; Corneal Injuries; Epithelium; Intraocular Pressure; Lidocaine; Rabbits; Tetracaine; Wound Healing | 1972 |
Effect of local anaesthetics on the accumulation of ( 3 H)-metaraminol by rabbit atria and vasa deferentia.
Topics: Anesthetics, Local; Animals; Cocaine; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male; Metaraminol; Myocardium; Prilocaine; Procaine; Rabbits; Tritium; Vas Deferens | 1972 |
Local anaesthetics.
Topics: Amides; Anesthetics, Local; Brain Edema; Cardiovascular Diseases; Central Nervous System Diseases; Cocaine; Dibucaine; Drug Hypersensitivity; Esters; Humans; Hypoxia; Lidocaine; Methemoglobinemia; Prilocaine; Procaine | 1971 |
[A powerful local anesthetic: 2-N-(beta-(4-propionyl-phenoxy)ethyl)amino-1-phenylpropane].
Topics: 1-Propanol; Anesthesia, Conduction; Anesthetics, Local; Animals; Cocaine; Female; Lidocaine; Male; Propylamines; Rabbits; Sciatic Nerve; Structure-Activity Relationship | 1971 |
The effect of local anesthetics on the central nervous system toxicity of hyperbaric oxygen.
Topics: Animals; Brain Chemistry; Central Nervous System Diseases; Cocaine; Dopamine; Hyperbaric Oxygenation; Lidocaine; Male; Mice; Norepinephrine; Oxygen; Serotonin | 1971 |
Bronchography: the rational use of premedication and local anesthesia.
Topics: Anesthetics, Local; Atropine; Body Weight; Bronchography; Bronchoscopy; Cocaine; Codeine; Cough; Dibucaine; Humans; Lidocaine; Methods; Pentobarbital; Phosphates; Premedication; Propiophenones; Tetracaine; Vasoconstrictor Agents | 1971 |
Abolition of impulse initiation at the Pacinian corpuscle by local anesthetics.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cats; Cocaine; Depression, Chemical; Lidocaine; Microscopy, Electron; Nerve Endings; Procaine; Sodium; Tetracaine | 1968 |
[Development of a screening method for testing of local anesthetics of leaf worm].
Topics: Anesthesia; Anesthetics, Local; Animals; Cocaine; Helminths; Hydrochloric Acid; Hydrogen-Ion Concentration; Lidocaine; Mepivacaine; Methods; Temperature; Tetracaine; Time Factors | 1969 |
Local anesthetics: inhibition of subcutaneous absorption in rats.
Topics: Absorption; Animals; Antipyrine; Cocaine; Depression, Chemical; Injections, Subcutaneous; Lidocaine; Phosphates; Phosphorus Isotopes; Prilocaine; Procaine; Rats; Tetracaine | 1970 |
Combined effects of some local anesthetics with sodium benzoate.
Topics: Anesthetics, Local; Animals; Benzoates; Cocaine; Cornea; Dental Pulp; Dibucaine; Drug Synergism; Hydrogen-Ion Concentration; Lidocaine; Procaine; Rabbits; Sodium; Tetracaine | 1970 |
Phospholipid model membranes. 3. Antagonistic effects of Ca2+ and local anesthetics on the permeability of phosphatidylserine vesicles.
Topics: Anesthetics, Local; Calcium; Cocaine; Dibucaine; Electrophoresis; Hydrogen-Ion Concentration; Lidocaine; Membranes, Artificial; Permeability; Phosphatidylethanolamines; Procaine; Sodium Isotopes; Tetracaine | 1970 |
Water structure in anesthetic action: time-dependence D2O effects on nerve.
Topics: Action Potentials; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Anura; Calcium; Cocaine; Depression, Chemical; Deuterium; Ethanol; Ethyl Ethers; Glucose; In Vitro Techniques; Lidocaine; Models, Biological; Neural Conduction; Nicotine; Ouabain; Oxides; Phosphates; Procaine; Sciatic Nerve; Stimulation, Chemical; Temperature; Time Factors; Water | 1970 |
Blind nasotracheal intubation. A review and a new guided technique.
Topics: Adolescent; Adult; Aged; Analgesia; Anesthesia, General; Anesthesia, Local; Arteries; Blood Pressure; Catheterization; Child; Cocaine; Cough; Epinephrine; Female; Hemorrhage; Humans; Hypoxia; Intubation, Intratracheal; Larynx; Lidocaine; Male; Methods; Middle Aged; Nasopharynx; Nose; Oxygen; Oxygen Inhalation Therapy; Posture; Preanesthetic Medication | 1971 |
The effect of local anesthetic and pH on sodium and potassium flux in human red cells.
Topics: Biological Transport, Active; Cell Membrane Permeability; Cocaine; Depression, Chemical; Dibucaine; Erythrocytes; Hematocrit; Hemolysis; Humans; Hydrogen-Ion Concentration; Lidocaine; Potassium; Potassium Isotopes; Procaine; Sodium; Sodium Isotopes; Tetracaine | 1968 |
Potentiation of morphine analgesia by cocaine in mice.
Topics: Amphetamine; Analgesia; Animals; Cocaine; Dibucaine; Drug Synergism; Female; Imipramine; Lidocaine; Male; Mice; Morphine; Norepinephrine; Phentolamine; Procaine; Rats; Reserpine | 1968 |
[Short review of Marcaine characteristics].
Topics: Anesthesia, Local; Anilides; Chemistry, Pharmaceutical; Cocaine; Humans; Lidocaine; Piperidines; Procaine; Xylenes | 1968 |
Local anaesthetic activity, irritancy and toxicity of seven new synthetic lignocaine analogues.
Topics: Anesthetics, Local; Animals; Cocaine; Cornea; Guinea Pigs; Lidocaine; Mice; Mucous Membrane; Rabbits | 1968 |
[Modification of the action of adrenaline, of noradrenaline and of tyramine on the isolated rat and guinea pig vas deferens under the influence of local anesthetics].
Topics: Amino Alcohols; Anesthetics, Local; Animals; Benzoates; Cocaine; Drug Synergism; Epinephrine; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Norepinephrine; Procaine; Receptors, Drug; Tetracaine; Tyramine; Vas Deferens | 1968 |
Action of prostaglandin E 1 on the longitudinal muscle of the guinea-pig isolated colon.
Topics: Acetylcholine; Animals; Cocaine; Colon; Guinea Pigs; In Vitro Techniques; Lidocaine; Muscle, Smooth; Nicotine; Prostaglandins; Scopolamine; Tetrodotoxin | 1969 |
Experimentally induced changes in nasalucous secretory systems and their effect on virus infection in chickens. II. Effects on adsorption of Newcastle disease virus.
Topics: Adsorption; Amino Alcohols; Animals; Chickens; Cocaine; Cold Temperature; Lidocaine; Mucus; Nasal Mucosa; Newcastle Disease; Newcastle disease virus; Pilocarpine; Turbinates | 1969 |
The effect of local anaesthesia of the pyloric antral mucosa on acid inhibition of gastrin-mediated acid secretion.
Topics: Acetylcholine; Anesthetics, Local; Animals; Cocaine; Dogs; Gastric Mucosa; Gastrins; Hydrogen-Ion Concentration; Lidocaine; Pylorus | 1965 |
Effect of cocaine and tyramine on noradrenaline release and uptake in isolated nerve vesicles.
Topics: Animals; Cattle; Cocaine; Lidocaine; Nerve Endings; Neurons; Norepinephrine; Procaine; Tetracaine; Tyramine | 1965 |
Ionization of bases with limited solubility. Investigation of substances with local anesthetic activity.
Topics: Anesthetics, Local; Buffers; Cocaine; Hydrogen-Ion Concentration; Ions; Lidocaine; Procaine; Solubility; Temperature | 1966 |
The contractile response of the uterus to cocaine.
Topics: Acetylcholine; Animals; Atropine; Calcium; Catecholamines; Cocaine; Dibucaine; Diethylstilbestrol; Epinephrine; Estrogens; Female; Glycerol; Hemolysis; Histamine; In Vitro Techniques; Lidocaine; Muscle Contraction; Norepinephrine; Oxytocin; Phenoxybenzamine; Procaine; Progesterone; Rabbits; Sensory Receptor Cells; Serotonin; Strontium; Tetracaine; Uterus | 1966 |
[Complexes of local anesthetics with adenine and ATP. On the action mechanism of local anesthesia].
Topics: Adenine; Adenosine Triphosphate; Anesthetics, Local; Buffers; Cocaine; In Vitro Techniques; Lidocaine; Mepivacaine; Models, Chemical; Procaine | 1966 |
[Clinical experimental studies of the effects of various local anesthetics on the cornea].
Topics: Adult; Anesthetics, Local; Animals; Cocaine; Cornea; Eye Foreign Bodies; Humans; Injections, Intradermal; Lidocaine; Rabbits; Tetracaine; Tonometry, Ocular | 1966 |
Neuroleptanalgesia for cataract surgery.
Topics: Adult; Aged; Anesthesia, Local; Benperidol; Cataract Extraction; Cocaine; Female; Humans; Hypoventilation; Lidocaine; Male; Middle Aged; Neuroleptanalgesia; Phenoperidine; Postoperative Complications; Preanesthetic Medication; Promethazine; Tonometry, Ocular | 1966 |
The effect of local anaesthetic and anti-adrenaline drugs on the response of sympathetically innervated smooth muscle preparations to electrical stimulation at different frequencies.
Topics: Amphetamine; Animals; Atropine; Cocaine; Electric Stimulation; Guinea Pigs; Ileum; Lidocaine; Magnesium; Male; Muscle, Smooth; Neuromuscular Junction; Norepinephrine; Phenoxybenzamine; Phentolamine; Physostigmine; Procaine; Rabbits; Rats; Sympathetic Nervous System; Sympatholytics; Vas Deferens; Yohimbine | 1966 |
Tolerance indices of some-beta-phenoxyethylamino derivatives with local anaesthetic properties.
Topics: Anesthetics, Local; Animals; Butyrophenones; Cocaine; Drug Tolerance; Erythrocytes; Ethylamines; Female; Intestinal Mucosa; Lidocaine; Male; Procaine; Rabbits; Skin | 1966 |
Smooth-muscle relaxant activities of some new beta-phenoxyethylamines.
Topics: Animals; Butyrophenones; Cocaine; Ethylamines; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Lidocaine; Mice; Muscle, Smooth; Muscles; Papaverine; Procaine; Rabbits; Rats; Uterus | 1966 |
Ortho-substituted beta-phenoxyethylamino derivatives. New local anaesthetic drugs.
Topics: Anesthetics, Local; Animals; Butyrophenones; Cocaine; Female; Guinea Pigs; Lidocaine; Male; Mice; Phenethylamines; Procaine; Rabbits; Rats | 1966 |
Cardiovascular and other pharmacologic activities of three beta-phenoxyethylamines with local-anesthetic activity.
Topics: Alcohols; Anesthetics, Local; Animals; Butyrophenones; Cardiovascular System; Cats; Cocaine; Dogs; Female; Heart; Lidocaine; Male; Mice; Nervous System; Procaine; Rabbits; Rats; Respiration | 1966 |
Origin of cocaine- and lidocaine-induced spindle activity within the olfactory forebrain of the rat.
Topics: Animals; Central Nervous System; Cocaine; Frontal Lobe; Lidocaine; Male; Olfactory Bulb; Olfactory Pathways; Rats | 1982 |
A suitable substitute for 4% cocaine before blind nasotracheal intubation: 3% lidocaine-0.25% phenylephrine nasal spray.
Topics: Anesthesia, Local; Blood Pressure; Cocaine; Double-Blind Method; Drug Combinations; Epistaxis; Heart Rate; Hemodynamics; Humans; Intubation, Intratracheal; Lidocaine; Nasal Decongestants; Nasal Mucosa; Phenylephrine; Random Allocation; Succinylcholine; Thiopental | 1984 |
Differential sensory and motor blockade after spinal cocaine in the rat and marmoset.
Topics: Analgesia; Anesthesia, Spinal; Animals; Bupivacaine; Callitrichinae; Cocaine; Dose-Response Relationship, Drug; Lidocaine; Male; Movement; Rats; Rats, Inbred Strains | 1984 |
Histopathology of the spinal cord after intrathecal cocaine, bupivacaine, lignocaine and adrenaline in the rat.
Topics: Animals; Bupivacaine; Catheterization; Cocaine; Epinephrine; Injections, Spinal; Lidocaine; Male; Neurons; Rats; Rats, Inbred Strains; Spinal Cord; Subarachnoid Space; Vacuoles | 1984 |
Short-term effects of local anaesthetic agents on the structure of the rat tympanic membrane.
Topics: Aerosols; Anesthetics, Local; Animals; Cocaine; Drug Combinations; Lidocaine; Male; Menthol; Phenols; Rats; Rats, Inbred Strains; Solutions; Time Factors; Tympanic Membrane | 1984 |
The effect of amygdala kindling on spontaneous and cocaine-induced motor activity and lidocaine seizures.
Topics: Amygdala; Animals; Apomorphine; Cocaine; Electric Stimulation; Humans; Lidocaine; Male; Motor Activity; Rats; Seizures; Stereotyped Behavior | 1981 |
Effect of lidocaine pretreatment on cocaine-induced behavior in normal and amygdala-lesioned rats.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Drug Interactions; Feeding and Eating Disorders; Feeding Behavior; Humans; Lidocaine; Male; Motor Activity; Rats; Rats, Inbred Strains | 1982 |
The comparative effects of prilocaine, lignocaine and cocaine on the response of the rabbit ear artery to adrenaline and noradrenaline.
Topics: Animals; Arteries; Blood Pressure; Cocaine; Drug Combinations; Drug Synergism; Ear, External; Epinephrine; Lidocaine; Norepinephrine; Perfusion; Prilocaine; Rabbits | 1982 |
The effects of cocaine and lignocaine on the rat right ventricle in vitro.
Topics: Animals; Cocaine; Electric Stimulation; Heart; Heart Rate; Lidocaine; Male; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains | 1982 |
Locomotor activity in morphine-treated rats: effects of and comparisons between cocaine, procaine, and lidocaine.
Topics: Animals; Cocaine; Humans; Lidocaine; Male; Morphine; Morphine Dependence; Motor Activity; Procaine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1981 |
Effect of cocaine and lidocaine on the expression of kindled seizures in the rat.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Cocaine; Electric Stimulation; Lidocaine; Male; Olfactory Bulb; Rats; Seizures | 1981 |
The role of benzoylmethylecgonine in cocaine-induced hepatotoxicity.
Topics: Alanine Transaminase; Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Cocaine; Lidocaine; Male; Mice; Procaine; Rats | 1981 |
Facilitation of kindling by convulsions induced by cocaine or lidocaine but not pentylenetetrazol.
Topics: Animals; Behavior, Animal; Cocaine; Electric Stimulation; Kindling, Neurologic; Lidocaine; Male; Olfactory Bulb; Pentylenetetrazole; Rats; Seizures | 1981 |
Modifications by lidocaine and its N-dealkylated metabolites of the response of the isolated rabbit aorta to transmural electrical stimulation.
Topics: Alkylation; Animals; Aorta, Thoracic; Bretylium Compounds; Calcium; Cocaine; Electric Stimulation; Lidocaine; Male; Muscle Contraction; Norepinephrine; Phentolamine; Potassium; Rabbits | 1980 |
The influence of endobronchial fluid on the ventilation.
Topics: Adult; Aged; Anesthetics, Local; Bronchi; Bronchitis; Cocaine; Contrast Media; Female; Forced Expiratory Volume; Humans; Lidocaine; Male; Maximal Midexpiratory Flow Rate; Middle Aged; Recurrence; Respiratory Function Tests; Vital Capacity | 1980 |
Qualitative differentiation between cocaine, lidocaine and cocaine-lidocaine mixtures ("rock-cocaine") using thin-layer chromatography.
Topics: Chromatography, Thin Layer; Cocaine; Drug Combinations; Illicit Drugs; Lidocaine; Pharmaceutical Preparations | 1980 |
Morphological changes of the corneal epithelium after application of topical anaesthetic ointments.
Topics: Anesthetics, Local; Animals; Cocaine; Corneal Diseases; Epithelium; Lidocaine; Microscopy, Electron, Scanning; Ointments; Procaine; Propoxycaine; Rabbits | 1980 |
Differential sensitivities of mammalian nerve fibers to local anesthetic agents.
Topics: Anesthetics; Animals; Bupivacaine; Cocaine; Etidocaine; Lidocaine; Nerve Fibers; Nerve Fibers, Myelinated; Procaine; Rabbits; Saxitoxin; Tetracaine; Tetrodotoxin | 1980 |
Clinical safety of lidocaine in patients with cocaine-associated myocardial infarction.
Topics: Adult; Cocaine; Emergencies; Female; Humans; Lidocaine; Male; Myocardial Infarction; Retrospective Studies; Substance-Related Disorders | 1995 |
Effect of cocaine on the 5-HT3 receptor-mediated ion current in Xenopus oocytes.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Ion Transport; Lidocaine; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Receptors, Serotonin; Serotonin; Xenopus laevis | 1995 |
In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter.
Topics: Aminobenzoates; Anesthetics, Local; Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Lidocaine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Procaine; Propanolamines; Rats; Rats, Sprague-Dawley; Software; Structure-Activity Relationship | 1995 |
Cocaine and the porcine coronary microcirculation: effects of chronic cocaine exposure and hypercholesterolemia.
Topics: Adrenergic alpha-Antagonists; Animals; Arterioles; Bradykinin; Cocaine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Hypercholesterolemia; Injections, Intramuscular; Isoproterenol; Lidocaine; Microcirculation; Muscarinic Antagonists; Nitroprusside; Phenylephrine; Procainamide; Prospective Studies; Receptors, Adrenergic, beta; Serotonin; Swine; Swine, Miniature; Vasoconstriction; Video Recording | 1995 |
Involvement of monoamine uptake inhibition and local anesthesia in the cardiovascular response to cocaine in conscious rabbits.
Topics: Anesthetics, Local; Animals; Blood Pressure; Cocaine; Electric Stimulation; Fluvoxamine; Heart Rate; Lidocaine; Maprotiline; Procaine; Rabbits; Sympathetic Nervous System | 1995 |
The effect of acute cocaine or lidocaine on behavioral function following fluid percussion brain injury in rats.
Topics: Animals; Behavior, Animal; Body Weight; Brain Injuries; Cocaine; Lidocaine; Male; Maze Learning; Motor Activity; Nervous System; Postural Balance; Rats; Rats, Sprague-Dawley; Time Factors; Wounds, Nonpenetrating | 1995 |
Cocaine-like discriminative stimulus effects of procaine, dimethocaine and lidocaine in rats.
Topics: Aminobenzoates; Anesthetics, Local; Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Lidocaine; Male; Procaine; Propanolamines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology | 1993 |
Acute cocaine administration alters posttraumatic blood pressure and cerebral blood flow in rats.
Topics: Animals; Blood Pressure; Brain Injuries; Carbon Dioxide; Cerebrovascular Circulation; Cocaine; Hydrogen-Ion Concentration; Lidocaine; Male; Methamphetamine; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Time Factors | 1995 |
Central administration of cocaine produces age-dependent effects on behavior in the fetal rat.
Topics: Animals; Arousal; Brain; Cocaine; Embryonic and Fetal Development; Female; Fetal Movement; Gestational Age; Lidocaine; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sucking Behavior | 1994 |
Role of dopamine D1 receptors in the lethal effects of cocaine and a quaternary methiodide analog.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Dopamine D2 Receptor Antagonists; Fenoldopam; Lidocaine; Male; Mice; Motor Activity; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, Dopamine D2; Seizures; Structure-Activity Relationship | 1993 |
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.
Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area | 1994 |
Contrasting actions of cocaine, local anaesthetic and tetrodotoxin on discharge properties of rat aortic baroreceptors.
Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Benzocaine; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Lidocaine; Male; Pressoreceptors; Pressure; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 1994 |
Vasoconstrictive effects of cocaine and lidocaine with epinephrine in the hamster cheek pouch model.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Arterioles; Cheek; Cocaine; Cricetinae; Epinephrine; Injections, Subcutaneous; Lidocaine; Male; Mesocricetus; Models, Biological; Mouth Mucosa; Sodium Chloride; Time Factors; Vasoconstrictor Agents | 1994 |
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1994 |
Post-reactivation cocaine administration facilitates later acquisition of an avoidance response in rats.
Topics: Anesthetics, Local; Animals; Avoidance Learning; Cocaine; Dose-Response Relationship, Drug; Electroshock; Lidocaine; Male; Memory; Rats; Rats, Sprague-Dawley | 1993 |
Trabecular outflow facility and formation rate of aqueous humor during intravenous cocaine or lidocaine in rabbits.
Topics: Anesthesia, Intravenous; Anesthetics, Local; Animals; Aqueous Humor; Cocaine; Lidocaine; Rabbits; Trabecular Meshwork | 1994 |
Influence of cocaine and lidocaine on human nasal cilia. Beat frequency and harmony in vitro.
Topics: Cilia; Cocaine; Dose-Response Relationship, Drug; Humans; Lidocaine; Movement; Nasal Mucosa | 1994 |
Body packing with a twist.
Topics: Cocaine; Female; Humans; Lidocaine; Male; Paraquat; Substance-Related Disorders | 1993 |
Effect of cocaine, lidocaine kindling and carbamazepine on batrachotoxin-induced phosphoinositide hydrolysis in rat brain slices.
Topics: Animals; Batrachotoxins; Brain Chemistry; Carbamazepine; Cocaine; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Lidocaine; Male; Phosphatidylinositols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channels | 1993 |
Hypertension and pulmonary oedema associated with ketamine administration in a patient with a history of substance abuse.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Spinal; Crack Cocaine; Female; Humans; Hypertension; Ketamine; Lidocaine; Phenobarbital; Pulmonary Edema; Substance-Related Disorders; Tachycardia | 1993 |
Cocaine inhibits hippocampal long-term potentiation.
Topics: Animals; Cocaine; Dextroamphetamine; Electric Stimulation; Hippocampus; In Vitro Techniques; Learning; Lidocaine; Memory; Neuronal Plasticity; Phosphorylation; Procaine; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
Cocaine concentration-effect relationship in the presence and absence of lidocaine: evidence of competitive binding between cocaine and lidocaine.
Topics: Action Potentials; Anesthetics, Local; Animals; Binding, Competitive; Cocaine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Conduction System; In Vitro Techniques; Lidocaine; Male; Papillary Muscles; Refractory Period, Electrophysiological; Sodium Channels | 1996 |
[Euphoric effect of lidocaine].
Topics: Adult; Cocaine; Euphoria; Humans; Lidocaine; Male; Mepivacaine; Substance Abuse, Intravenous; Substance-Related Disorders | 1996 |
A comparison of topical Emla cream with Bonain's solution for anesthesia of the tympanic membrane during tympanocentesis.
Topics: Adolescent; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Combinations; Female; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Male; Menthol; Middle Aged; Middle Ear Ventilation; Ointments; Pain Measurement; Phenols; Prilocaine; Solutions; Tympanic Membrane | 1996 |
Cholinergic stimulation modulates negative inotropic effect of cocaine on ferret ventricular myocardium.
Topics: Animals; Atropine; Carbachol; Cell Separation; Cholinergic Agents; Cocaine; Cyclic AMP; Ferrets; Intracellular Membranes; Lidocaine; Myocardial Contraction; Myocardium; Papillary Muscles; Procaine; Ventricular Function | 1996 |
Centrally mediated hemodynamic effects of cocaine in rabbits: the role of local anesthetic actions and biogenic amine re-uptake blockage.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Biogenic Monoamines; Blood Pressure; Central Nervous System; Cocaine; Desipramine; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intraventricular; Lidocaine; Male; Neurotransmitter Uptake Inhibitors; Rabbits | 1996 |
Conditions sufficient for the production of oral cocaine or lidocaine self-administration in preference to water.
Topics: Administration, Oral; Animals; Choice Behavior; Cocaine; Drinking; Lidocaine; Male; Motivation; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration | 1996 |
Pharmacological characterization of the enhancement of apomorphine-induced gnawing in mice by cocaine.
Topics: Anesthetics, Local; Animals; Apomorphine; Cocaine; Dextroamphetamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Lidocaine; Male; Mice; Mice, Inbred C57BL; Stereotyped Behavior | 1996 |
One-way cross-sensitization and cross-tolerance to seizure activity from cocaine to lidocaine.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cocaine; Drug Tolerance; Lidocaine; Male; Mice; Polyamines; Seizures | 1996 |
Intrategmental infusion of cocaine decreases dopamine release and enhances norepinephrine release in the medial prefrontal cortex.
Topics: Anesthetics, Local; Animals; Catecholamines; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Extracellular Space; Injections; Lidocaine; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tegmentum Mesencephali | 1996 |
Effect of sub-chronic cocaine and lidocaine exposure on the lymphoid tissues in neonatal rats.
Topics: Animals; Animals, Newborn; Body Weight; Cocaine; Female; Immunoglobulin M; Leukocytes; Lidocaine; Lymphoid Tissue; Male; Organ Size; Rats; Rats, Inbred Lew; Spleen; Tissue Distribution | 1996 |
Intravenous lidocaine decreases but cocaine does not alter the rate of cerebrospinal fluid formation in anesthetized rabbits.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Blood Pressure; Cerebral Ventricles; Cerebrospinal Fluid; Cocaine; Dose-Response Relationship, Drug; Electroencephalography; Heart Rate; Infusions, Intravenous; Intracranial Pressure; Lidocaine; Rabbits; Regression Analysis | 1997 |
Topical analgesia for children.
Topics: Administration, Topical; Anesthetics, Local; Child; Cocaine; Drug Combinations; Epinephrine; Gels; Humans; Lidocaine; Wounds and Injuries | 1997 |
Effects of intranasal cocaine on sympathetic nerve discharge in humans.
Topics: Administration, Intranasal; Adult; Baroreflex; Cocaine; Echocardiography; Ganglia, Sympathetic; Humans; Lidocaine; Male; Muscle, Skeletal; Norepinephrine; Sinoatrial Node | 1997 |
Cardiovascular consequences of fibreoptic bronchoscopy.
Topics: Adjuvants, Anesthesia; Age Factors; Aged; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Blood Pressure Monitors; Bronchoscopes; Bronchoscopy; Bundle-Branch Block; Cocaine; Droperidol; Electrocardiography; Female; Fentanyl; Fiber Optic Technology; Forced Expiratory Volume; Heart Rate; Humans; Lidocaine; Male; Monitoring, Physiologic; Oximetry; Prospective Studies; Smoking; Tachycardia | 1997 |
Cocaine and lidocaine in combination are synergistic convulsants.
Topics: Animals; Cocaine; Drug Synergism; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
Decreased cocaine- and lidocaine-induced seizure response by dextromethorphan and DNQX in rat.
Topics: Anesthetics, Local; Animals; Cocaine; Dextromethorphan; Excitatory Amino Acid Antagonists; Incidence; Injections, Intravenous; Lidocaine; Male; Narcotics; Quinoxalines; Rats; Rats, Sprague-Dawley; Seizures | 1997 |
Establishing preference for oral cocaine without an associative history with a reinforcer.
Topics: Administration, Oral; Animals; Association Learning; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Lidocaine; Male; Motivation; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Taste | 1997 |
Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity.
Topics: Anesthetics, Local; Animals; Cell Line; Cocaine; Evoked Potentials; Heart; Humans; Kidney; Kinetics; Lidocaine; Membrane Potentials; Models, Chemical; Muscle, Skeletal; Patch-Clamp Techniques; Rats; Recombinant Proteins; Sodium Channels; Transfection | 1997 |
Mazindol and lidocaine are antinociceptives in the mouse formalin model: involvement of dopamine receptor.
Topics: Anesthetics, Local; Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; Lidocaine; Male; Mazindol; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Dopamine; Receptors, Opioid | 1997 |
Negative inotropic effect of methylecgonidine, a major product of cocaine base pyrolysis, on ferret and human myocardium.
Topics: Adjuvants, Anesthesia; Anesthetics, Local; Animals; Atropine; Cocaine; Cyclic AMP; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ferrets; Humans; Lidocaine; Male; Myocardial Contraction; Nitric Oxide Synthase; Papillary Muscles | 1997 |
Repairing lacerations in children.
Topics: Anesthetics, Local; Child; Child, Preschool; Cocaine; Dermatologic Surgical Procedures; Drug Therapy, Combination; Epinephrine; Humans; Lidocaine; Skin; Tetracaine; Vasoconstrictor Agents; Wounds and Injuries | 1997 |
Role of cerebral spermidine in the development of sensitization to convulsant activity of cocaine and lidocaine.
Topics: Animals; Brain Chemistry; Cocaine; Convulsants; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Excitatory Amino Acid Agonists; Injections, Intravenous; Lidocaine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Putrescine; Seizures; Spermidine | 1997 |
Case report of an unusual use of lidocaine during episodes of self mutilation.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Autopsy; Chromatography, Gas; Cocaine; Dextromoramide; Drug Combinations; Forensic Medicine; Hair; Humans; Lidocaine; Male; Methadone; Self Mutilation; Substance Abuse Detection; Substance-Related Disorders | 1998 |
Is lidocaine contraindicated with cocaine?
Topics: Cocaine; Cocaine-Related Disorders; Drug Synergism; Humans; Lidocaine | 1997 |
Alternative routes of drug administration--advantages and disadvantages (subject review)
Topics: Administration, Oral; Analgesics, Opioid; Anesthetics, Combined; Cocaine; Epinephrine; Fentanyl; Humans; Iontophoresis; Lidocaine; Mouth Mucosa; Tetracaine | 1998 |
Xylocaine: 50 years of clinical service to dentistry.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Cocaine; History, 20th Century; Humans; Lidocaine; Procaine; United States | 1998 |
Cocaine and lidocaine with phenylephrine as topical anesthetics: antimicrobial activity against common nasal pathogens.
Topics: Administration, Topical; Ampicillin; Anesthetics, Local; Bacteria; Cocaine; Drug Resistance, Microbial; Humans; Lidocaine; Microbial Sensitivity Tests; Nasal Cavity; Penicillins; Phenylephrine; Vasoconstrictor Agents | 1998 |
Differential participation of hippocampal formation in cocaine-induced cortical electroencephalographic desynchronization and penile erection in the rat.
Topics: Animals; Blood Pressure; Cocaine; Cortical Synchronization; Dopamine Uptake Inhibitors; Electroencephalography; Heart Rate; Hippocampus; Lidocaine; Male; Microinjections; Penile Erection; Rats; Rats, Sprague-Dawley; Spinal Cord; Subarachnoid Space | 1998 |
State-dependent stimulus control: cuing attributes of acute cocaine rebound in rats.
Topics: Animals; Chlordiazepoxide; Cocaine; Discrimination, Psychological; Lidocaine; Male; N-Methylaspartate; Narcotics; Rats; Rats, Sprague-Dawley; Self Administration | 1998 |
[The Bonain anesthetic mixture: a forgotten ancestor of Emla cream?].
Topics: Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Humans; Lidocaine; Lidocaine, Prilocaine Drug Combination; Menthol; Ointments; Phenols; Prilocaine | 1998 |
Adulterants encountered in the illicit cocaine market.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Drug Contamination; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Lidocaine; Rome | 1998 |
Lidocaine and benzalkonium analysis and titration in drugs using new ISFET devices.
Topics: Benzalkonium Compounds; Biosensing Techniques; Chemistry, Pharmaceutical; Cocaine; In Vitro Techniques; Lidocaine; Reproducibility of Results; Surface-Active Agents; Titrimetry | 1998 |
Cocaine and lidocaine have additive inhibitory effects on the GABAA current of acutely dissociated hippocampal pyramidal neurons.
Topics: Anesthetics, Combined; Animals; Cocaine; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Lidocaine; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Channels | 1999 |
[Local anesthesia in endonasal paranasal sinus operations].
Topics: Anesthesia, Local; Cocaine; Endoscopy; Hemostasis, Surgical; Humans; Lidocaine; Paranasal Sinus Diseases | 1998 |
Validation of animal experiments on ciliary function in vitro. I. The influence of substances used clinically.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Chick Embryo; Cocaine; Cryopreservation; Humans; Hydrogen-Ion Concentration; Imidazoles; Lidocaine; Mucociliary Clearance; Mucous Membrane; Nasal Decongestants; Oxymetazoline; Propranolol; Trachea | 1999 |
Cocaine stimulates the human cardiovascular system via a central mechanism of action.
Topics: Administration, Intranasal; Adrenergic beta-Antagonists; Adult; Cardiovascular System; Cocaine; Dopamine Uptake Inhibitors; Female; Heart Rate; Humans; Lidocaine; Male; Microelectrodes; Muscarinic Antagonists; Norepinephrine; Reference Values; Skin; Sympathetic Nervous System; Volunteers | 1999 |
Comparison of cocaine and Na+ channel blockers on cardio-respiratory function in the rabbit.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cocaine; Dopamine Uptake Inhibitors; Electrocardiography; Female; Flecainide; Heart; Heart Rate; Lidocaine; Male; Procainamide; Quinidine; Rabbits; Respiration; Sodium Channel Blockers | 1999 |
Comparison of oxymetazoline and lidocaine versus cocaine for outpatient dacryocystorhinostomy.
Topics: Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Dacryocystorhinostomy; Humans; Lidocaine; Nasolacrimal Duct; Nebulizers and Vaporizers; Oxymetazoline; Vasoconstrictor Agents | 2000 |
Insecticidal activity of common reagents for insect foreign bodies of the ear.
Topics: Acetic Acid; Anesthetics, Local; Animals; Anti-Infective Agents, Local; Bees; Chlorhexidine; Cocaine; Cockroaches; Coleoptera; Detergents; Ear Canal; Ethanol; Foreign Bodies; Humans; Hydrogen Peroxide; Insecta; Insecticides; Lidocaine; Linear Models; Prospective Studies; Saline Solution, Hypertonic; Single-Blind Method; Solvents; Statistics, Nonparametric; Tetracaine; Ticks; Time Factors; Videotape Recording | 2001 |
Mechanisms of cocaine-induced decreases in immune cell function.
Topics: Animals; Cocaine; Corticosterone; Hypothalamo-Hypophyseal System; Immunosuppressive Agents; Lidocaine; Lymphocyte Activation; Male; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley | 2001 |
Two procedures establishing preference for oral cocaine and lidocaine solutions which do not use an associative history with a reinforcer.
Topics: Animals; Association Learning; Choice Behavior; Cocaine; Conditioning, Classical; Drinking; Lidocaine; Male; Motivation; Quinine; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Taste | 2001 |
[The history of local anesthesia].
Topics: Anesthesia, Dental; Anesthetics, Local; Cocaine; History, 19th Century; History, 20th Century; Humans; Lidocaine | 1996 |
Local anaesthetic endonasal endoscopic laser dacryocystorhinostomy: analysis of patients' acceptability and various factors affecting the success of this procedure.
Topics: Administration, Topical; Adrenergic Agonists; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; Dacryocystorhinostomy; Endoscopy; Epinephrine; Follow-Up Studies; Humans; Intraoperative Complications; Laser Therapy; Lidocaine; Pain; Patient Satisfaction; Surveys and Questionnaires; Treatment Outcome | 2002 |
Stimulus-response functions of the lateral dorsal striatum and regulation of behavior studied in a cocaine maintenance/cue reinstatement model in rats.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cues; Discrimination Learning; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Infusions, Intravenous; Lidocaine; Male; Photic Stimulation; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Time Factors | 2002 |
Summaries for patients. Body heat management in people using cocaine.
Topics: Adult; Body Temperature Regulation; Cocaine; Double-Blind Method; Esophagus; Female; Fever; Humans; Lidocaine; Male; Sensory Thresholds; Skin; Sweating; Vasodilation | 2002 |
Effect of veratrine alkaloids on the efflux of extra-granular noradrenaline from rabbit atria.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Biological Transport; Catechol O-Methyltransferase Inhibitors; Cocaine; Colchicine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Atria; In Vitro Techniques; Lidocaine; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rabbits; Reserpine; Tetrodotoxin; Veratrine | 1976 |
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lidocaine; Male; Maprotiline; Mice; Mice, Inbred ICR; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Seizures; Selective Serotonin Reuptake Inhibitors; Symporters; Time Factors | 2003 |
Up-regulation of GABA(B) receptor mRNA and protein in the hippocampus of cocaine- and lidocaine-kindled rats.
Topics: Animals; Behavior, Animal; Blotting, Western; Cocaine; Dose-Response Relationship, Drug; Hippocampus; In Situ Hybridization; Kindling, Neurologic; Lidocaine; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Seizures; Time Factors | 2003 |
The action of cocaïne, procaïne, xylocaïne and their combination with adrenaline on the blood pressure.
Topics: Anesthetics; Anesthetics, Local; Blood Pressure; Blood Pressure Determination; Cocaine; Epinephrine; Humans; Lidocaine; Procaine | 1953 |
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine; Cocaine; Convulsive Therapy; Electroconvulsive Therapy; Fever; Hexobarbital; Histamine; Hypothermia; Hypothermia, Induced; Lidocaine; Lobeline; Morphine; Papaverine; Phenobarbital; Promethazine; Thiopental | 1962 |
SOME RECENT STUDIES ON THE CLINICAL PHARMACOLOGY OF LOCAL ANESTHETICS OF PRACTICAL SIGNIFICANCE.
Topics: Adjuvants, Anesthesia; Anesthetics; Anesthetics, Local; Cocaine; Dibucaine; Humans; Lidocaine; Metabolism; Pharmacology; Procaine; Tetracaine | 1963 |
CURRENT VIEW OF ANESTHESIA FOR OBSTETRICS BASED UPON OUR TOTAL EXPERIENCE.
Topics: Anesthesia; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics; Anesthetics, Local; Cocaine; Delivery, Obstetric; Female; Heart Failure; Humans; Lidocaine; Maternal Mortality; Mepivacaine; Obstetrics; Ohio; Perineum; Pregnancy; Procaine; Tetracaine | 1963 |
[CASES OF SHOCK-LIKE CONDITIONS. (6)].
Topics: Adenoidectomy; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Otolaryngology; Shock; Shock, Septic; Tonsillectomy; Toxicology | 1963 |
[CASE OF SHOCK CAUSED BY LOCAL ANESTHESIA].
Topics: Anesthesia, Local; Blood Transfusion; Cocaine; Drug Hypersensitivity; Lidocaine; Oxygen Inhalation Therapy; Shock; Shock, Septic; Tonsillectomy; Toxicology | 1963 |
[5 RECENT CASES OF LOCAL ANESTHETIC TOXICITY IN TONSILLECTOMY].
Topics: Anesthesia, Local; Anesthetics, Local; Child; Cocaine; Drug Hypersensitivity; Lidocaine; Pharmacology; Physiology; Procaine; Shock; Shock, Septic; Spasm; Tonsillectomy; Toxicology | 1963 |
[EFFECT OF PROCAINE AND OTHER LOCAL ANESTHETICS ON HEART ANAPHYLAXIS].
Topics: Anaphylaxis; Anesthetics, Local; Animals; Antigens; Blood Volume Determination; Cocaine; Coronary Vessels; Dibucaine; Guinea Pigs; Heart; Lidocaine; Ovalbumin; Procaine; Research | 1963 |
ANAESTHETISING THE ARM.
Topics: Anesthesia; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthesia, Local; Anesthesiology; Arm; Brachial Plexus; Cocaine; Humans; Injections; Injections, Intra-Arterial; Lidocaine; Neck; Neurologic Manifestations; Pneumothorax; Postoperative Complications; Procaine | 1964 |
CLINICAL EFFECTIVENESS OF DRUGS USED FOR TOPICAL ANESTHESIA.
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Benzocaine; Cocaine; Dibucaine; Electric Stimulation; Humans; Lidocaine; Lip; Mepivacaine; Mucous Membrane; Palate; Pharmacology; Procaine; Sympathomimetics; Tetracaine; Tongue; Treatment Outcome; Tripelennamine | 1964 |
THE EFFECTS OF ANESTHETICS UPON THE EAR. V. COCHLEAR POTENTIALS AND BEHAVIORAL THRESHOLDS.
Topics: Anesthetics; Cats; Cocaine; Cochlea; Conditioning, Classical; Ear, Inner; Hearing; Hearing Tests; Lidocaine; Pharmacology; Physiology; Reflex; Research; Surgical Procedures, Operative | 1964 |
COMPARATIVE PHARMACOLOGICAL STUDIES OF GANGLIONIC STIMULANTS: DIMETHYLPHENYLPIPERAZINIUM BROMIDE (DMPP), TETRAMETHYLAMMONIUM BROMIDE (TMA) AND GANGLIONIC STIMULANTS OF THE TROPINE TYPE. I.
Topics: Ammonium Compounds; Animals; Atropine; Blood Pressure; Blood Pressure Determination; Bromides; Cats; Chloralose; Cocaine; Dimethylphenylpiperazinium Iodide; Dogs; Ganglionic Stimulants; Guinea Pigs; Hexamethonium Compounds; Lidocaine; Nictitating Membrane; Pentobarbital; Pharmacology; Piperazines; Procaine; Quaternary Ammonium Compounds; Rabbits; Research; Respiration; Sympatholytics; Sympathomimetics; Tropanes | 1964 |
GAS CHROMATOGRAPHY OF HIGH-BOILING AMINES. II. DETERMINATION OF AMINES IN LOW CONCENTRATION.
Topics: Amines; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cocaine; Codeine; Ephedrine; Lidocaine; Methadone; Morphine; Pharmacy; Promazine; Research; Scopolamine | 1964 |
POTENTIATION OF THE NERVE-DEPRESSANT EFFECT OF LOCAL ANAESTHETICS BY CARBON DIOXIDE.
Topics: Anesthesia; Anesthesia, Local; Anesthetics, Local; Carbon Dioxide; Cocaine; Lidocaine; Nerve Tissue; Neural Conduction; Peripheral Nerves; Pharmacology; Physiology; Procaine; Rats; Research; Sciatic Nerve | 1964 |
EFFECTS OF LOCAL ANESTHETICS ON SODIUM AND POTASSIUM IN HUMAN RED CELLS.
Topics: Anesthetics, Local; Cocaine; Computers, Analog; Dibucaine; Electronic Data Processing; Erythrocytes; Hemolysis; Humans; Ions; Lidocaine; Metabolism; Pharmacology; Potassium; Procaine; Research; Sodium; Tetracaine | 1965 |
INHIBITION OF THE SECRETIN MECHANISM BY LOCAL ANESTHETICS.
Topics: Anesthetics; Anesthetics, Local; Animals; Cocaine; Dogs; Gastrins; Hydrochloric Acid; Lidocaine; Pancreatic Juice; Pharmacology; Physiology; Research; Secretin | 1965 |
[CONTRIBUTION TO THE MECHANISM OF ACTION OF LOCAL ANESTHETICS].
Topics: Anesthetics, Local; Animals; Anura; Cell Membrane; Cocaine; Electrophysiological Phenomena; Electrophysiology; Lidocaine; Pharmacology; Procaine; Ranidae; Research; Water-Electrolyte Balance | 1965 |
RECENT ADVANCES IN LOCAL ANALGESIA. CLINICAL EXPERIENCE WITH PRILOCAINE.
Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Bronchoscopy; Cocaine; Humans; Lidocaine; Pain; Pharmacology; Prilocaine; Statistics as Topic; Tetracaine; Toxicology | 1965 |
ELECTRICAL ACTIVITY IN THE CHEMORECEPTORS OF THE BLOWFLY. 3. DENDRITIC ACTION POTENTIALS.
Topics: Action Potentials; Animals; Chemoreceptor Cells; Chloral Hydrate; Cocaine; Dendrites; Diptera; Electrophysiology; Lidocaine; Neurons; Pharmacology; Procaine; Research; Sensory Receptor Cells; Sodium Chloride; Tetrodotoxin | 1965 |
THE R OLE OF THE VESICAL MUCOSA IN REFLEX MICTURITION.
Topics: Animals; Capsaicin; Capsicum; Cocaine; Dogs; Lidocaine; Mucous Membrane; Nerve Endings; Pharmacology; Reflex; Research; Urinary Bladder; Urination | 1965 |
Lidocaine inactivation of ventral subiculum attenuates cocaine-seeking behavior in rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Drug Antagonism; Extinction, Psychological; Feeding Behavior; Hippocampus; Lidocaine; Male; Microinjections; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2003 |
Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nerves.
Topics: Action Potentials; Anesthetics, Local; Animals; Axotomy; Cells, Cultured; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Lidocaine; Neurons; Patch-Clamp Techniques; Peripheral Nerves; Rats; Sciatic Nerve; Spinal Nerve Roots | 2004 |
Cocaine affects prostaglandin production in human umbilical cord cell cultures.
Topics: Cells, Cultured; Cocaine; Cocaine-Related Disorders; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Female; Humans; Lidocaine; Pregnancy; Pregnancy Complications; Procaine; Umbilical Veins | 2003 |
Electrophysiologic properties of lidocaine, cocaine, and n-3 fatty-acids block of cardiac Na+ channels.
Topics: Animals; Cells, Cultured; Cocaine; Electrophysiology; Fatty Acids, Omega-3; Humans; Lidocaine; Male; Membrane Potentials; Myocytes, Cardiac; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels | 2004 |
Hippocampal memory system function and the regulation of cocaine self-administration behavior in rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extinction, Psychological; Hippocampus; Lidocaine; Male; Maze Learning; Memory; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology; Self Administration | 2004 |
About an unusual case: GC-MS detection of lidocaine.
Topics: Adult; Anesthetics, Local; Arrhythmias, Cardiac; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Gallbladder; Gas Chromatography-Mass Spectrometry; Hair; Humans; Kidney; Lidocaine; Liver; Male; Spleen | 2004 |
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Benzazepines; Cocaine; Desipramine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Neurotransmitter Uptake Inhibitors; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrodotoxin | 2005 |
Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Lidocaine; Male; Mice; Mice, Inbred ICR; Receptor, Serotonin, 5-HT2C; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2005 |
Down-regulation of norepinephrine transporter function induced by chronic administration of desipramine linking to the alteration of sensitivity of local-anesthetics-induced convulsions and the counteraction by co-administration with local anesthetics.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Desipramine; Down-Regulation; Drug Interactions; Lidocaine; Male; Mice; Mice, Inbred ICR; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Seizures; Sodium Channel Blockers | 2006 |
The inhibitory effects of local anesthetics on primary sensory nerve and parasympathetic nerve in rabbit eye.
Topics: Anesthetics, Local; Animals; Atropine; Autonomic Pathways; Carbachol; Cholinergic Fibers; Cocaine; Inflammation; Iris; Lidocaine; Male; Neurokinin A; Optic Nerve; Parasympathetic Nervous System; Rabbits; Substance P | 2006 |
Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects.
Topics: Anesthetics, Local; Animals; Blood Pressure; Body Temperature; Brain; Calcium; Cocaine; Dopamine Uptake Inhibitors; Female; Heart Rate; Hemoglobins; Heterocyclic Compounds, 3-Ring; Intracellular Fluid; Lidocaine; Methylphenidate; Rats; Rats, Sprague-Dawley; Spectrum Analysis | 2006 |
Context-dependent prefrontal cortex regulation of cocaine self-administration and reinstatement behaviors in rats.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Environment; Environment, Controlled; Lidocaine; Male; Neural Pathways; Odorants; Photic Stimulation; Prefrontal Cortex; Rats; Reward; Self Administration | 2006 |
Local anaesthetic shortages continue to affect dentists.
Topics: Anesthetics, Local; Cocaine; Dentists; Equipment Design; Government Regulation; Humans; Illicit Drugs; Ireland; Lidocaine; Safety; Syringes | 2007 |
Effectiveness of mouthpiece nebulization and nasal swab stick packing for topical anesthesia in awake fiberoptic nasotracheal intubation.
Topics: Administration, Topical; Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; Elective Surgical Procedures; Female; Fiber Optic Technology; Humans; Intubation, Intratracheal; Lidocaine; Male; Middle Aged; Patient Satisfaction; Prospective Studies; Psychometrics; Wakefulness | 2007 |
Hippocampal regulation of contextual cue-induced reinstatement of cocaine-seeking behavior.
Topics: Acoustic Stimulation; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Food; Hippocampus; Lidocaine; Male; Microinjections; Rats; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration; Smell | 2008 |
Access and binding of local anesthetics in the closed sodium channel.
Topics: Anesthetics, Local; Binding Sites; Cocaine; Computer Simulation; Conotoxins; Lidocaine; Ligands; Models, Biological; Models, Molecular; Molecular Structure; Monte Carlo Method; Mutation; Protein Conformation; Sodium; Sodium Channels; Static Electricity; Tetracaine; Tetrodotoxin; Water | 2008 |
Skill-memory consolidation in the striatum: critical for late but not early long-term memory and stabilized by cocaine.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Learning; Lidocaine; Male; Memory; Microinjections; Motor Activity; Motor Skills; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Case files of the medical toxicology fellowship at the toxikon consortium in Chicago: cocaine-associated wide-complex dysrhythmias and cardiac arrest - treatment nuances and controversies.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Antidotes; Arrhythmias, Cardiac; Charcoal; Cocaine; Electrocardiography; Emergency Medical Services; Female; Heart Arrest; Humans; Lidocaine; Lorazepam; Pulse; Seizures; Sodium Bicarbonate; Sympathomimetics; Tachycardia, Ventricular; Young Adult | 2008 |
A study of the thermal decomposition of adulterated cocaine samples under optimized aerobic pyrolytic conditions.
Topics: Acetaminophen; Administration, Inhalation; Calorimetry, Differential Scanning; Cocaine; Drug Combinations; Drug Contamination; Hot Temperature; Lidocaine; Magnetic Resonance Spectroscopy; Procaine; Smoke; Smoking; Volatilization | 2009 |
Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Catheterization; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Frontal Lobe; Lidocaine; Male; Rats; Rats, Wistar; Self Administration | 2009 |
Chronic cocaine enhances corticotropin-releasing factor-dependent potentiation of excitatory transmission in ventral tegmental area dopamine neurons.
Topics: Analysis of Variance; Anesthetics, Local; Aniline Compounds; Animals; Biophysics; Cocaine; Corticotropin-Releasing Hormone; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lidocaine; Male; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Pyrimidines; Time Factors; Ventral Tegmental Area | 2009 |
Composition, purity and perceived quality of street cocaine in France.
Topics: Acetaminophen; Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Data Collection; Diltiazem; Drug Contamination; Drug Users; Female; France; Humans; Illicit Drugs; Lidocaine; Male; Middle Aged; Smoking; Young Adult | 2010 |
Interaction of the rostral basolateral amygdala and prelimbic prefrontal cortex in regulating reinstatement of cocaine-seeking behavior.
Topics: Amygdala; Anesthetics, Local; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Data Interpretation, Statistical; Extinction, Psychological; Functional Laterality; Lidocaine; Limbic System; Male; Neural Pathways; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rats, Wistar; Recurrence; Reinforcement Schedule; Self Administration | 2010 |
Effects of lidocaine-induced inactivation of the bed nucleus of the stria terminalis, the central or the basolateral nucleus of the amygdala on the opponent-process actions of self-administered cocaine in rats.
Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Lidocaine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Septal Nuclei | 2011 |
Moffett's solution - is it safe? The UK experience.
Topics: Anesthetics, Local; Attitude of Health Personnel; Cocaine; Dose-Response Relationship, Drug; Drug Approval; Drug-Related Side Effects and Adverse Reactions; Epinephrine; Humans; Lidocaine; Nasal Decongestants; Off-Label Use; Pharmaceutical Solutions; Preoperative Care; Sodium Bicarbonate; Surveys and Questionnaires; United Kingdom | 2011 |
Cocaine modulates pathways for photic and nonphotic entrainment of the mammalian SCN circadian clock.
Topics: Animals; Circadian Clocks; Cocaine; Dopamine Uptake Inhibitors; Fluphenazine; Lidocaine; Male; Metergoline; Mice; Mice, Inbred C57BL; Models, Animal; Motor Activity; Photic Stimulation; Serotonin Receptor Agonists; Signal Transduction; Suprachiasmatic Nucleus | 2012 |
Effect of topical anesthetic agents and ethanol on corneoepithelial wound healing in an ex vivo whole-globe porcine model.
Topics: Administration, Topical; Anesthesia, Local; Anesthetics, Local; Animals; Cocaine; Epithelium, Corneal; Ethanol; Keratectomy, Subepithelial, Laser-Assisted; Lasers, Excimer; Lidocaine; Models, Animal; Ophthalmic Solutions; Procaine; Swine; Tetracaine; Wound Healing | 2012 |
Impact of medial orbital cortex and medial subthalamic nucleus inactivation, individually and together, on the maintenance of cocaine self-administration behavior in rats.
Topics: Anesthetics, Local; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Frontal Lobe; Lidocaine; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Subthalamic Nucleus | 2013 |
Overinhibition of corticostriatal activity following prenatal cocaine exposure.
Topics: Age Factors; Analysis of Variance; Anesthetics, Local; Animals; Biophysics; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Female; GABA Agents; Green Fluorescent Proteins; Hindlimb Suspension; In Vitro Techniques; Interneurons; Lidocaine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Quinoxalines; Quinpirole; Receptors, GABA-A; Rotarod Performance Test; Sodium Channel Blockers; Statistics, Nonparametric; Tetrodotoxin | 2013 |
Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking.
Topics: Acetylcholine; Anesthetics, Local; Animals; Benzazepines; Cholinergic Antagonists; Cocaine; Cues; Dopamine; Dopamine Agonists; Drug-Seeking Behavior; Lidocaine; Male; Mecamylamine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine; Time Factors; Valine; Ventral Tegmental Area | 2013 |
Purity and adulterant analysis of crack seizures in Brazil.
Topics: Aminobenzoates; Benzene; Biphenyl Compounds; Brazil; Caffeine; Chromatography, Gas; Chromatography, Liquid; Crack Cocaine; Cyclooctanes; Drug Contamination; Lidocaine; Mass Spectrometry; Naphthalenes; Nitriles; Pyridines; Smoke | 2014 |
Liquid-phase microextraction based on two immiscible organic solvents followed by gas chromatography with mass spectrometry as an efficient method for the preconcentration and determination of cocaine, ketamine, and lidocaine in human urine samples.
Topics: Anesthetics; Chromatography, Gas; Cocaine; Humans; Ketamine; Lidocaine; Liquid Phase Microextraction; Mass Spectrometry | 2014 |
Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.
Topics: Acetaminophen; Acetone; Adolescent; Adult; Aged; Chromatography, Liquid; Coca; Cocaine; Cocaine-Related Disorders; Drug and Narcotic Control; Drug Contamination; Female; Forensic Toxicology; Hair; Humans; Levamisole; Lidocaine; Male; Mass Spectrometry; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Tea | 2015 |
Ethanol and cocaine: environmental place conditioning, stereotypy, and synergism in planarians.
Topics: Animals; Cocaine; Conditioning, Psychological; Drug Synergism; Ethanol; Lidocaine; Planarians; Stereotyped Behavior | 2014 |
Profiling cocaine by ATR-FTIR.
Topics: Caffeine; Cluster Analysis; Cocaine; Discriminant Analysis; Dopamine Uptake Inhibitors; Drug Contamination; Humans; Lidocaine; Phenacetin; Principal Component Analysis; Spectroscopy, Fourier Transform Infrared | 2015 |
Analysis of cocaine and its adulterants in drugs for international trafficking seized by the Brazilian Federal Police.
Topics: Aminopyrine; Brazil; Caffeine; Cocaine; Crime; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Levamisole; Lidocaine; Narcotics; Phenacetin | 2015 |
From cocaine to lidocaine: great progress with a tragic ending.
Topics: Anesthesia, Local; Anesthetics, Local; Cocaine; Drug Industry; History, 19th Century; History, 20th Century; Humans; Lidocaine; Molecular Structure; Structure-Activity Relationship | 2015 |
Drug-related death: adulterants from cocaine preparations in lung tissue and blood.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Diltiazem; Drug Contamination; Forensic Toxicology; Humans; Hydroxyzine; Illicit Drugs; Levamisole; Lidocaine; Liquid-Liquid Extraction; Lung; Mass Spectrometry; Narcotics; Phenacetin; Solid Phase Extraction | 2015 |
Thin layer chromatography coupled to paper spray ionization mass spectrometry for cocaine and its adulterants analysis.
Topics: Benzocaine; Caffeine; Chromatography, Thin Layer; Cocaine; Drug Contamination; Humans; Lidocaine; Mass Spectrometry; Narcotics; Phenacetin | 2016 |
A survey of adulterants used to cut cocaine in samples seized in the Espírito Santo State by GC-MS allied to chemometric tools.
Topics: Caffeine; Cocaine; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Lidocaine; Narcotics; Principal Component Analysis | 2016 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |
Wavenumber selection method to determine the concentration of cocaine and adulterants in cocaine samples.
Topics: Caffeine; Cocaine; Drug Contamination; Levamisole; Lidocaine | 2018 |
Analysis of cocaine adulterants in human brain in cases of drug-related death.
Topics: Brain Chemistry; Cetirizine; Cocaine; Cocaine-Related Disorders; Diltiazem; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyzine; Levamisole; Lidocaine; Narcotics; Phenacetin; Reproducibility of Results; Solid Phase Extraction | 2018 |
Balloon Eustachian tuboplasty under monitored anaesthesia care with different balloon dilation devices: A pilot feasibility study with 18 patients.
Topics: Adult; Aged; Anesthesia, Local; Anesthetics, Local; Cocaine; Dilatation; Epinephrine; Eustachian Tube; Feasibility Studies; Female; Humans; Lidocaine; Male; Middle Aged; Pain Measurement; Pilot Projects; Prilocaine | 2019 |
Toxicological analysis of cocaine adulterants in blood samples.
Topics: Atropine; Cocaine; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyzine; Ketamine; Lidocaine; Narcotics; Phenacetin; Tetramisole | 2019 |
Does Lidocaine Cause False Positive Results on Cocaine Urine Drug Screen?
Topics: Adult; Cocaine; Cross-Sectional Studies; False Positive Reactions; Female; Humans; Lidocaine; Male; Middle Aged; Substance Abuse Detection; Urinalysis | 2019 |
Adulterants in crack cocaine in Brazil.
Topics: Adolescent; Adult; Brazil; Cocaine-Related Disorders; Crack Cocaine; Drug Contamination; Female; Hair; Humans; Levamisole; Lidocaine; Male; Phenacetin; Young Adult | 2019 |
An optical sensor for the detection and quantification of lidocaine in cocaine samples.
Topics: Cocaine; Drug Contamination; Lidocaine | 2020 |
When the front fails, the rear wins. Cerebellar correlates of prefrontal dysfunction in cocaine-induced memory in male rats.
Topics: Animals; Cerebellum; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Interneurons; Lidocaine; Male; Nerve Net; Prefrontal Cortex; Rats; Reward | 2022 |
Cutting agents in cocaine: A temporal study of the period 2015-2017 in the Northern Region of Colombia.
Topics: Aporphines; Caffeine; Cocaine; Codeine; Colombia; Drug Contamination; Drug Trafficking; Humans; Imidazoles; Levamisole; Lidocaine; Phenacetin; Spatio-Temporal Analysis; Tetramisole | 2021 |
Qualitative LC-Q-TOF Analysis of Umbilical Cord Tissue via Data-Dependent Acquisition as an Indicator of In Utero Exposure to Toxic Adulterating Substances.
Topics: Analgesics, Opioid; Caffeine; Cocaine; Diphenhydramine; Drug Contamination; Female; Humans; Levamisole; Lidocaine; Phenacetin; Pregnancy; Umbilical Cord; Xylazine | 2022 |
Plastic antioxidants: A family of cocaine cutting agents analyzed by short column gas chromatography-mass spectrometry.
Topics: Antioxidants; Cocaine; Gas Chromatography-Mass Spectrometry; Lidocaine; Plastics | 2022 |
Reagentless Voltammetric Identification of Cocaine from Complex Powders.
Topics: Benzocaine; Caffeine; Carbon Fiber; Cocaine; Levamisole; Lidocaine; Powders; Procaine; Water | 2022 |
Regulation of bite force increase during splitting of food.
Topics: Adaptation, Physiological; Adult; Anesthesia, Dental; Anesthetics, Local; Arachis; Biomechanical Phenomena; Bite Force; Candy; Female; Food; Hardness; Humans; Incisor; Lidocaine; Male; Mastication; Mechanoreceptors; Periodontium; Time Factors; Young Adult | 2009 |