cocaine and labetalol

cocaine has been researched along with labetalol in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19909 (31.03)18.7374
1990's7 (24.14)18.2507
2000's6 (20.69)29.6817
2010's7 (24.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Kennedy, I; Levy, GP1
Doggrell, SA; Paton, DM1
Goldberg, SR; Schindler, CW; Tella, SR1
Etzel, R1
Atwood, J; Walsh, M1
Karch, SB1
Gay, GR; Loper, KA2
Bessen, HA1
Dusenberry, SJ; Hicks, MJ; Mariani, PJ1
Doggrell, SA; Hughes, EW1
Badger, TM; Burge, LJ; Creer, MH; Karba, R; Nehus, C; Primozic, S; Scalzo, FM1
Parr, MJ2
Bowles, R1
Boehrer, JD; Hillis, LD; Lange, RA; Moliterno, DJ; Willard, JE1
Babb, DA; Brown, S; Hatsukami, DK; Pentel, PR; Sofuoglu, M1
Baud, F; Couchard, AC; Ekhérian, JM; Goldgran-Tolédano, D; Mégarbane, B1
Wu, D; Yee, LM1
Kloner, RA; Rezkalla, SH; Stankowski, RV1
Lange, RA; Richards, JR1
Lange, RA; Laurin, EG; Richards, JR; Tabish, N1
Arnold, TC; Horowitz, BZ; Lange, RA; Richards, JR1

Trials

1 trial(s) available for cocaine and labetalol

ArticleYear
Effects of labetalol treatment on the physiological and subjective response to smoked cocaine.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: Adrenergic Antagonists; Behavior, Addictive; Blood Pressure; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Cross-Over Studies; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heart Rate; Humans; Labetalol; Male

2000

Other Studies

28 other study(ies) available for cocaine and labetalol

ArticleYear
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Combined alpha- and beta-adrenoceptor blocking drug AH 5158: further studies on alpha-adrenoceptor blockade in anaesthetized animals.
    British journal of pharmacology, 1975, Volume: 53, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cats; Cocaine; Dogs; Drug Interactions; Ethanolamines; Female; Heart Rate; Labetalol; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Spinal Cord

1975
Effect of labetalol on the accumulation and release of noradrenaline in rat ventricle.
    European journal of pharmacology, 1978, Oct-01, Volume: 51, Issue:3

    Topics: Animals; Cocaine; Ethanolamines; Labetalol; Myocardium; Norepinephrine; Phenethylamines; Rats; Tyramine

1978
Adrenoceptor mechanisms in the cardiovascular effects of cocaine in conscious squirrel monkeys.
    Life sciences, 1992, Volume: 51, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cocaine; Heart Rate; Labetalol; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saimiri; Yohimbine

1992
"Cardiovascular effects of cocaine".
    The Journal of cardiovascular nursing, 1992, Volume: 7, Issue:1

    Topics: Cocaine; Humans; Hypertension; Labetalol; Tachycardia

1992
Cocaine, pulmonary edema, and propranolol.
    Annals of internal medicine, 1989, May-15, Volume: 110, Issue:10

    Topics: Animals; Cocaine; Humans; Labetalol; Propranolol; Pulmonary Edema

1989
Managing cocaine crisis.
    Annals of emergency medicine, 1989, Volume: 18, Issue:2

    Topics: Arrhythmias, Cardiac; Cocaine; Diazepam; Humans; Hypertension; Labetalol; Seizures; Substance-Related Disorders

1989
Control of cocaine-induced hypertension with labetalol.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:1

    Topics: Adult; Cocaine; Emergencies; Humans; Hypertension; Labetalol; Male

1988
The use of labetalol in the management of cocaine crisis.
    Annals of emergency medicine, 1988, Volume: 17, Issue:3

    Topics: Adult; Cocaine; Hematuria; Humans; Hypertension; Labetalol; Male; Resuscitation; Tachycardia, Supraventricular

1988
Treatment of cocaine toxicity.
    Annals of emergency medicine, 1987, Volume: 16, Issue:8

    Topics: Cocaine; Humans; Labetalol

1987
Labetalol treatment of cocaine toxicity.
    Annals of emergency medicine, 1987, Volume: 16, Issue:2

    Topics: Adult; Cocaine; Humans; Labetalol; Male; Substance-Related Disorders

1987
Comparison of the effects of labetalol and SCH 19927, the R1R isomer of labetalol, on the rat isolated right ventricle and aorta.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:4

    Topics: Animals; Aorta; Cocaine; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Idazoxan; In Vitro Techniques; Isoproterenol; Labetalol; Male; Myocardial Contraction; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Vasoconstriction

1985
Effects of labetalol on cocaine pharmacokinetics in neonatal piglets.
    Developmental pharmacology and therapeutics, 1993, Volume: 20, Issue:1-2

    Topics: Animals; Animals, Newborn; Cocaine; Drug Evaluation, Preclinical; Labetalol; Models, Biological; Swine

1993
Drug smuggler's delirium.
    BMJ (Clinical research ed.), 1993, Apr-10, Volume: 306, Issue:6883

    Topics: Adrenergic beta-Antagonists; Cocaine; Drug and Narcotic Control; Humans; Labetalol; Poisoning; Propanolamines

1993
Cocaine dosage in rhinosurgery.
    Anaesthesia, 1993, Volume: 48, Issue:8

    Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Cocaine; Humans; Labetalol; Propanolamines

1993
Cardiovascular complications of cocaine abuse.
    American family physician, 1993, Volume: 47, Issue:5

    Topics: Cocaine; Humans; Labetalol; Phentolamine; Receptors, Adrenergic, alpha; Vasoconstriction

1993
Influence of labetalol on cocaine-induced coronary vasoconstriction in humans.
    The American journal of medicine, 1993, Volume: 94, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Angina Pectoris; Cocaine; Female; Humans; Labetalol; Male; Middle Aged

1993
[Surgery to save body-packers].
    Annales francaises d'anesthesie et de reanimation, 2004, Volume: 23, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Arrhythmias, Cardiac; Cocaine; Digestive System Surgical Procedures; Drug Therapy, Combination; Emergency Medical Services; Epinephrine; Female; Humans; Ileostomy; Ileum; Intestinal Obstruction; Intestinal Perforation; Labetalol; Laparotomy; Male; Peritonitis; Poisoning; Radiography; Substance-Related Disorders

2004
False-positive amphetamine toxicology screen results in three pregnant women using labetalol.
    Obstetrics and gynecology, 2011, Volume: 117, Issue:2 Pt 2

    Topics: Adult; Amphetamine; Antihypertensive Agents; Cesarean Section; Chronic Disease; Cocaine; Cross Reactions; False Positive Reactions; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypertension, Pregnancy-Induced; Immunoassay; Infant, Newborn; Labetalol; Nifedipine; Pregnancy; Pregnancy Outcome; Pulmonary Edema; Stillbirth; Substance Abuse Detection

2011
Letter to the editor response.
    Trends in cardiovascular medicine, 2016, Volume: 26, Issue:2

    Topics: Angina Pectoris; Cocaine; Female; Humans; Labetalol; Male

2016
Labetalol and cardiovascular consequences of cocaine use.
    Trends in cardiovascular medicine, 2016, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Diseases; Cocaine; Cocaine-Related Disorders; Female; Humans; Labetalol; Male

2016
Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Analgesics; Cocaine; Emergency Service, Hospital; Epistaxis; Humans; Hypertension; Labetalol; Male; Middle Aged; Tachycardia; Vasoconstrictor Agents

2017
Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravenous; Adrenergic beta-Antagonists; Amphetamine-Related Disorders; Anti-Anxiety Agents; Anxiety; Cardiovascular Diseases; Cardiovascular System; Central Nervous System Stimulants; Chest Pain; Cocaine; Cocaine-Related Disorders; Drug Interactions; Electrocardiography; Humans; Hyperhidrosis; Labetalol; Lorazepam; Male; Methamphetamine; Sodium Chloride; Tachycardia; Young Adult

2017