cocaine and ketoconazole

cocaine has been researched along with ketoconazole in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's7 (53.85)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Jia, L; Sun, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Collins, ED; Fischman, MW; Foltin, RW; Haney, M; Ward, AS1
Goeders, NE; Mantsch, JR2
Broadbear, JH; Winger, G; Woods, JH1
Campbell, UC; Carroll, ME1
Clampitt, DM; Goeders, NE1
Goeders, NE; Smagin, GN1

Other Studies

13 other study(ies) available for cocaine and ketoconazole

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Ketoconazole attenuates the cortisol response but not the subjective effects of smoked cocaine in humans.
    Behavioural pharmacology, 1998, Volume: 9, Issue:7

    Topics: Administration, Inhalation; Adrenocorticotropic Hormone; Adult; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hydrocortisone; Ketoconazole; Male; Regression Analysis; Reinforcement, Psychology; Surveys and Questionnaires

1998
Ketoconazole blocks the stress-induced reinstatement of cocaine-seeking behavior in rats: relationship to the discriminative stimulus effects of cocaine.
    Psychopharmacology, 1999, Volume: 142, Issue:4

    Topics: Animals; Antifungal Agents; Cocaine; Corticosterone; Discrimination Learning; Ketoconazole; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Stress, Psychological

1999
Cocaine-reinforced responding in rhesus monkeys: pharmacological attenuation of the hypothalamic-pituitary-adrenal axis response.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Animals; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Etomidate; Glucocorticoids; Hypnotics and Sedatives; Hypothalamo-Hypophyseal System; Ketoconazole; Macaca mulatta; Male; Neuroprotective Agents; Peptide Fragments; Pituitary-Adrenal System; Reinforcement, Psychology

1999
Ketoconazole does not block cocaine discrimination or the cocaine-induced reinstatement of cocaine-seeking behavior.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:1

    Topics: Animals; Antifungal Agents; Catheterization; Cocaine; Cocaine-Related Disorders; Corticosterone; Discrimination, Psychological; Dopamine Uptake Inhibitors; Electroshock; Extinction, Psychological; Ketoconazole; Male; Rats; Rats, Wistar

1999
Effects of ketoconazole on the acquisition of intravenous cocaine self-administration under different feeding conditions in rats.
    Psychopharmacology, 2001, Volume: 154, Issue:3

    Topics: Animals; Antifungal Agents; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Food Deprivation; Injections, Intravenous; Ketoconazole; Male; Rats; Rats, Wistar; Reinforcement, Psychology; Satiation; Self Administration

2001
Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats.
    Psychopharmacology, 2002, Volume: 161, Issue:3

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Extinction, Psychological; Hypothalamo-Hypophyseal System; Ketoconazole; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Stress, Psychological

2002
Effects of acute and chronic ketoconazole administration on hypothalamo--pituitary--adrenal axis activity and brain corticotropin-releasing hormone.
    Psychoneuroendocrinology, 2004, Volume: 29, Issue:10

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Appetitive Behavior; Cocaine; Corticotropin-Releasing Hormone; Dopamine; Drug Administration Schedule; Enzyme Inhibitors; Hypothalamo-Hypophyseal System; Ketoconazole; Male; Pituitary-Adrenal System; Prefrontal Cortex; Rats; Rats, Wistar; Self Administration

2004