cocaine and ketanserin

cocaine has been researched along with ketanserin in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's11 (30.56)18.2507
2000's14 (38.89)29.6817
2010's6 (16.67)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glennon, RA1
Eshleman, AJ; Gonzalez, M; Janowsky, A; Johnson, RA; Kryatova, O; Meltzer, PC; Nelson, J; Provencher, BA; Shi, X; Tian, J1
Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D1
Borowsky, B; Kuhn, CM1
Rapoza, D; Woolverton, WL1
Frenken, M1
Meehan, AG; Story, DF1
Cohen, RA1
Kilbinger, H; Pfeuffer-Friederich, I1
Fiorella, D; Johnson, RG; Rabin, RA1
Bellver, A; Celentano, MM; de la Riva, IJ; Rosón, MI; Vega, GW1
Essman, WD; Lucki, I; Singh, A1
Elliott, P; Wallis, DI1
Davis, JM; Javaid, JI; Pandey, SC; Sahni, SK1
Lacosta, S; Roberts, DC1
Byrd, LD; Howell, LL; Schama, KF1
Herges, S; Taylor, DA1
Appel, SB; Brodie, MS; Bunney, EB2
Reith, ME; Yan, Q; Yan, S1
Hashim, A; Lajtha, A; Sershen, H1
Gessa, GL; Marchese, G; Pani, L; Ruiu, S; Saba, PL1
Cunningham, KA; McMahon, LR1
Ranaldi, R; Wise, RA1
Filip, M; Nowak, E; Papla, I1
Goldberg, SR; Justinova, Z; Kutkat, SW; Munzar, P1
Davidson, C; Ellinwood, EH; Lazarus, C; Lee, TH; Xiong, X1
Hayase, T; Muso, E; Shiota, K; Yamamoto, K; Yamamoto, Y1
Broderick, PA; Olabisi, OA; Rahni, DN; Zhou, Y1
Brierley, DI; Davidson, C1
Daniju, Y; Davidson, C; Dawson, P; Dutta, N; Moffatt, JD; Opacka-Juffry, J; Ramsey, J1
Milewski, A; Rawls, SM; Reitz, AB; Saber, I; Walker, EA1
Makiguchi, A; Okada, T; Shioda, K; Suda, S1

Other Studies

36 other study(ies) available for cocaine and ketanserin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter.
    Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; HEK293 Cells; Humans; Ligands; Mice; Quinazolines; Vesicular Monoamine Transport Proteins

2018
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; In Vitro Techniques; Indoles; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Renal Artery; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Sympathectomy; Tetrahydronaphthalenes; Tyramine; Vasoconstrictor Agents; Vasodilation

1991
Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Biogenic Monoamines; Cocaine; Corticosterone; Dopamine; Dopamine Antagonists; Haloperidol; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Ketanserin; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Piperazines; Pituitary-Adrenal System; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stimulation, Chemical; Time Factors

1991
Attenuation of the effects of cocaine on milk consumption in rats by dopamine antagonists.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:1

    Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drinking Behavior; Ketanserin; Male; Milk; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides

1991
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: Animals; Basilar Artery; Cocaine; Dogs; In Vitro Techniques; Indomethacin; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Spiperone; Vasoconstriction

1989
Interaction of the prejunctional inhibitory action of 5-hydroxytryptamine on noradrenergic transmission with neuronal amine uptake in rabbit isolated ear artery.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: Animals; Arteries; Cocaine; Ear, External; Female; In Vitro Techniques; Ketanserin; Male; Methiothepin; Neurons; Norepinephrine; Phentolamine; Rabbits; Receptors, Serotonin; Serotonin

1989
Contractions of isolated canine coronary arteries resistant to S2-serotonergic blockade.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:2

    Topics: Angiotensin II; Animals; Blood Platelets; Cocaine; Coronary Vessels; Cyproheptadine; Dibenzothiepins; Dinoprost; Dogs; Drug Resistance; Endothelium; Femoral Artery; In Vitro Techniques; Ketanserin; Methiothepin; Piperidines; Potassium; Prostaglandins F; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Vasoconstriction

1986
Two types of receptors for 5-hydroxytryptamine on the cholinergic nerves of the guinea-pig myenteric plexus.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Acetylcholine; Animals; Binding, Competitive; Cocaine; Electric Stimulation; Female; Guinea Pigs; Ketanserin; Male; Methiothepin; Methysergide; Metoclopramide; Muscle Contraction; Myenteric Plexus; Piperidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropanes

1985
Effects of chronic cocaine administration on the serotonergic system in the rat brain.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin

1993
Nitric oxide and superoxide anions in vascular reactivity of renovascular hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:5

    Topics: Animals; Aorta, Abdominal; Catalase; Cocaine; Hypertension, Renovascular; In Vitro Techniques; Ketanserin; Male; Methylene Blue; Nitric Oxide; Pentanoic Acids; Pyridines; Rats; Rats, Wistar; Serotonin; Superoxide Dismutase; Superoxides; Thromboxane-A Synthase; Vasoconstriction; Vasodilation

1995
Serotonergic properties of cocaine: effects on a 5-HT2 receptor-mediated behavior and on extracellular concentrations of serotonin and dopamine.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Extracellular Space; Ketanserin; Male; Microdialysis; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission

1994
Glutamatergic and non-glutamatergic responses evoked in neonatal rat lumbar motoneurons on stimulation of the lateroventral spinal cord surface.
    Neuroscience, 1993, Volume: 56, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Citalopram; Cocaine; Desipramine; Electric Stimulation; Ergolines; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Serotonin Antagonists; Spinal Cord; Strychnine; Synapses

1993
Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Cerebral Cortex; Cocaine; Corpus Striatum; Hippocampus; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereotyped Behavior

1993
MDL 72222, ketanserin, and methysergide pretreatments fail to alter breaking points on a progressive ratio schedule reinforced by intravenous cocaine.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:1

    Topics: Animals; Cocaine; Conditioning, Operant; Injections, Intravenous; Ketanserin; Male; Methysergide; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Serotonin Antagonists; Tropanes

1993
Serotonergic modulation of the discriminative-stimulus effects of cocaine in squirrel monkeys.
    Psychopharmacology, 1997, Volume: 132, Issue:1

    Topics: Animals; Cocaine; Discrimination Learning; Drug Interactions; Ketanserin; Male; Narcotics; Quipazine; Saimiri; Serotonin Agents

1997
Involvement of serotonin in the modulation of cocaine-induced locomotor activity in the rat.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Drug Interactions; Female; Fluoxetine; Ketanserin; Methysergide; Motor Activity; Narcotics; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

1998
Cocaine potentiates ethanol-induced excitation of dopaminergic reward neurons in the ventral tegmental area.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Animals; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Drug Synergism; Ethanol; Extracellular Space; Ketanserin; Neurons; Rats; Rats, Inbred F344; Reward; Serotonin Antagonists; Sulpiride; Ventral Tegmental Area

2000
Enhanced accumbal dopamine release following 5-HT(2A) receptor stimulation in rats pretreated with intermittent cocaine.
    Brain research, 2000, Apr-28, Volume: 863, Issue:1-2

    Topics: Amphetamines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Ketanserin; Male; Microdialysis; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Time Factors

2000
Serotonin-mediated striatal dopamine release involves the dopamine uptake site and the serotonin receptor.
    Brain research bulletin, 2000, Volume: 53, Issue:3

    Topics: Animals; Bicuculline; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Ketanserin; Male; Methiothepin; Mice; Mice, Inbred C57BL; Oxymetazoline; Piperazines; Quinoxalines; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2000
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
    Molecular psychiatry, 2000, Volume: 5, Issue:6

    Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium

2000
Antagonism of 5-hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Discrimination Learning; Dopamine; Fluorobenzenes; Ketanserin; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists

2001
Electrophysiological effects of cocaethylene, cocaine, and ethanol on dopaminergic neurons of the ventral tegmental area.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:2

    Topics: Animals; Central Nervous System Depressants; Cocaine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrophysiology; Ethanol; Extracellular Space; In Vitro Techniques; Ketanserin; Neurons; Rats; Rats, Inbred F344; Serotonin Antagonists; Sulpiride; Ventral Tegmental Area

2001
Blockade of D1 dopamine receptors in the ventral tegmental area decreases cocaine reward: possible role for dendritically released dopamine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Benzazepines; Cocaine; Cocaine-Related Disorders; Dendrites; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Antagonism; Drug Synergism; Ketanserin; Male; Microinjections; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Reinforcement, Psychology; Reward; Self Administration; Serotonin Antagonists; Ventral Tegmental Area

2001
On the role of serotonin2A/2C receptors in the sensitization to cocaine.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:3

    Topics: Animals; Cocaine; Ketanserin; Male; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin

2001
Differential involvement of 5-HT(2A) receptors in the discriminative-stimulus effects of cocaine and methamphetamine.
    European journal of pharmacology, 2002, Feb-01, Volume: 436, Issue:1-2

    Topics: Analysis of Variance; Animals; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Indophenol; Ketanserin; Male; Methamphetamine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2002
5-HT2 receptor antagonists given in the acute withdrawal from daily cocaine injections can reverse established sensitization.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: Animals; Behavior, Animal; Clozapine; Cocaine; Injections; Ketanserin; Male; Mianserin; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Substance Withdrawal Syndrome

2002
Stressor-like effects of cocaine on heat shock protein and stress-activated protein kinase expression in the rat hippocampus: interaction with ethanol and anti-toxicity drugs.
    Legal medicine (Tokyo, Japan), 2003, Volume: 5 Suppl 1

    Topics: Animals; Azides; Benzazepines; Benzodiazepines; Central Nervous System Depressants; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Ethanol; Heat-Shock Proteins; Hippocampus; Infusions, Parenteral; Ketanserin; Male; Mitogen-Activated Protein Kinases; Motor Activity; Muscarinic Antagonists; Pirenzepine; Rats; Serotonin Antagonists; Swimming

2003
Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:3

    Topics: Animals; Biogenic Monoamines; Calibration; Cocaine; Dopamine; Electrophysiology; Ketanserin; Male; Microelectrodes; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists

2004
Harmine augments electrically evoked dopamine efflux in the nucleus accumbens shell.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:1

    Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Agonists; Harmine; Ketanserin; Male; Moclobemide; Monoamine Oxidase Inhibitors; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Serotonin

2013
The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2014, Jan-03, Volume: 48

    Topics: Animals; Aorta; Benzofurans; Brain; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; In Vitro Techniques; Iodine Isotopes; Ketanserin; Male; Muscle Contraction; N-Methyl-3,4-methylenedioxyamphetamine; Propylamines; Protein Binding; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Serotonin Agents; Tritium; Vasoconstriction

2014
Effects of dopaminergic and serotonergic compounds in rats trained to discriminate a high and a low training dose of the synthetic cathinone mephedrone.
    Psychopharmacology, 2019, Volume: 236, Issue:3

    Topics: Alkaloids; Animals; Benzazepines; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Illicit Drugs; Ketanserin; Male; Methamphetamine; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Serotonin Antagonists

2019
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
    The international journal of neuropsychopharmacology, 2020, 12-29, Volume: 23, Issue:12

    Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists

2020