cocaine and isradipine

cocaine has been researched along with isradipine in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (53.85)	18.2507
2000's	6 (23.08)	29.6817
2010's	4 (15.38)	24.3611
2020's	2 (7.69)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Calcagnetti, DJ; Schechter, MD	3
Fratta, W; Gessa, GL; Kuzmin, A; Martellotta, MC; Zvartau, E	1
Fratta, W; Gessa, GL; Kuzmin, A; Martellotta, MC; Pani, L	1
Fratta, W; Gessa, GL; Kuzmin, A; Martellotta, MC; Muglia, P	1
Schechter, MD	1
Cramer, CM; Hubbell, CL; Pabello, NG; Reid, LD	1
Boswell, KJ; Gonzales, PM; Hubbell, CL; Reid, LD	1
Abramson, D; Barron, B; Chen, R; Dhother, S; Fang, B; Johnson, B; Kenny, P; Kramer, L; Lamki, L; Overton, D; Wagner, L; Wells, L	1
Boedeker, KL; Cramer, CM; Gardell, LR; Harris, JR; Hubbell, CL; Reid, LD	1
Ali, SF; Arsah, TA; Mills, K; Shockley, DC	1
Cramer, CM; Hubbell, CL; Reid, LD	1
Burgess, SE; Cavallero, CA; Gardell, LR; Hubbell, CL; Reid, LD; Reid, ML; Wallace, RF	1
Ait-Daoud, N; Johnson, BA; Mauldin, JB; Roache, JD; Wells, LT	1
Ait-Daoud, N; Dawes, MA; Johnson, BA; Roache, JD; Wallace, CL; Wang, Y; Wells, LT	1
Ait-Daoud, N; Johnson, BA; Roache, JD; Wallace, C; Wang, Y; Wells, LT	1
Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT	1
Ahn, KC; Degoulet, M; Morikawa, H; Stelly, CE	1
Addy, NA; Baracz, SJ; Haight, JL; Hughley, SM; Nunes, EJ; Rajadhyaksha, AM; Small, KM	1
Pierce, RC; Swinford-Jackson, SE	1
Antigua, SA; Babij, R; Bavley, CC; Burgdorf, CE; Contoreggi, NH; De Marco García, NV; Fetcho, RN; Fischer, DK; Hackett, JE; Hall, BS; Kash, TL; Liston, C; Milner, TA; Rajadhyaksha, AM; Sayles, NM; Walsh, AP	1
Gebhardt, ES; Kaur, K; Morikawa, H; Natal, S; Perrone, A; Smits, JAJ; Tirado, C; Young, CC	1

Reviews

1 review(s) available for cocaine and isradipine

Article	Year
Applications of isradipine in human addiction studies: A systematic literature review. Experimental and clinical psychopharmacology, 2023, Volume: 31, Issue:2 Topics: Adult; Calcium Channel Blockers; Cocaine; Humans; Isradipine; Methamphetamine; Substance-Related Disorders	2023

Trials

4 trial(s) available for cocaine and isradipine

Article	Year
Effects of isradipine on cocaine-induced subjective mood. Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:2 Topics: Adolescent; Adult; Affect; Area Under Curve; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isradipine; Male; Reproducibility of Results; Reward; Stimulation, Chemical; Surveys and Questionnaires	2004
Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individuals. The international journal of neuropsychopharmacology, 2005, Volume: 8, Issue:4 Topics: Adult; Area Under Curve; Attention; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Isradipine; Male; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychomotor Performance; Reaction Time	2005
Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies. American journal of hypertension, 2005, Volume: 18, Issue:6 Topics: Adult; Amphetamine-Related Disorders; Blood Pressure; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Injections, Intravenous; Isradipine; Male; Methamphetamine; Stroke	2005
Effects of repeated-dose isradipine on the abuse liability of cocaine. Experimental and clinical psychopharmacology, 2005, Volume: 13, Issue:4 Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Euphoria; Female; Headache; Heart Rate; Humans; Infusions, Intravenous; Isradipine; Male; Middle Aged; Nausea; Tablets; Treatment Outcome	2005

Other Studies

21 other study(ies) available for cocaine and isradipine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Psychostimulant-induced activity is attenuated by two putative dopamine release inhibitors. Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4 Topics: Alkaloids; Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Antagonists; Injections, Intraventricular; Isradipine; Male; Motor Activity; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Thiazepines	1992
Attenuation of drinking sweetened water following calcium channel blockade. Brain research bulletin, 1992, Volume: 28, Issue:6 Topics: Animals; Calcium Channel Blockers; Cocaine; Dihydropyridines; Dose-Response Relationship, Drug; Drinking Behavior; Female; Injections, Intraventricular; Isradipine; Male; Rats; Rats, Inbred Strains; Reward; Taste	1992
Calcium antagonists isradipine and nimodipine suppress cocaine and morphine intravenous self-administration in drug-naive mice. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:3 Topics: Animals; Calcium Channel Blockers; Cocaine; Dihydropyridines; Dopamine; Injections, Intravenous; Isradipine; Mice; Morphine; Nimodipine; Reinforcement, Psychology; Reward; Self Administration	1992
The calcium antagonist PN 200-110 inhibits the reinforcing properties of cocaine. Brain research bulletin, 1991, Volume: 26, Issue:3 Topics: Animals; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Isradipine; Male; Motor Activity; Oxadiazoles; Rats; Rats, Inbred Strains; Reinforcement, Psychology	1991
Effects of the calcium antagonist isradipine on cocaine intravenous self-administration in rats. Psychopharmacology, 1994, Volume: 113, Issue:3-4 Topics: Animals; Calcium Channel Blockers; Cocaine; Dose-Response Relationship, Drug; Injections, Intravenous; Isradipine; Male; Rats; Self Administration; Stereoisomerism	1994
Cocaine discrimination is attenuated by isradipine and CGS 10746B. Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3 Topics: Animals; Antipsychotic Agents; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Ibogaine; Isradipine; Male; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Thiazepines; Tropanes	1993
Isradipine produces neither a conditioned place preference nor aversion. Life sciences, 1994, Volume: 54, Issue:6 Topics: Animals; Cocaine; Conditioning, Operant; Isradipine; Male; Rats; Rats, Sprague-Dawley	1994
Isradipine in combination with naltrexone as a medicine for treating cocaine abuse. Life sciences, 1997, Volume: 60, Issue:8 Topics: Animals; Calcium Channel Blockers; Cocaine; Drug Therapy, Combination; Electric Stimulation; Isradipine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance-Related Disorders	1997
Isradipine blocks cocaine's ability to facilitate pressing for intracranial stimulation. Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:4 Topics: Animals; Calcium Channel Blockers; Cocaine; Isradipine; Male; Medial Forebrain Bundle; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward; Self Stimulation	1997
Isradipine prevents global and regional cocaine-induced changes in brain blood flow: a preliminary study. Psychopharmacology, 1998, Volume: 136, Issue:4 Topics: Adult; Brain; Calcium Channel Blockers; Cerebral Arteries; Cocaine; Female; Humans; Isradipine; Male; Narcotics; Regional Blood Flow; Substance-Related Disorders; Tomography, Emission-Computed, Single-Photon	1998
Isradipine combined with naltrexone persistently reduces the reward-relevant effects of cocaine and alcohol. Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:2 Topics: Animals; Body Weight; Calcium Channel Blockers; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Drinking; Drug Interactions; Ethanol; Isradipine; Male; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Reward	1998
Calcium channel antagonist isradipine attenuates cocaine-induced motor activity in rats: correlation with brain monoamine levels. Annals of the New York Academy of Sciences, 1998, May-30, Volume: 844 Topics: Animals; Behavior, Animal; Brain; Calcium Channel Blockers; Caudate Nucleus; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Isradipine; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Stereotyped Behavior	1998
A combination of isradipine and naltrexone blocks cocaine's enhancement of a cocaine place preference. Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:4 Topics: Animals; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Isradipine; Male; Mental Recall; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance-Related Disorders	1998
Amlodipine, a calcium channel inhibitor, and cocaine and ethanol's reinforcing effects. Pharmacology, biochemistry, and behavior, 1999, Volume: 64, Issue:3 Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Isradipine; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology	1999
L-type Ca²⁺ channel blockade with antihypertensive medication disrupts VTA synaptic plasticity and drug-associated contextual memory. Molecular psychiatry, 2016, Volume: 21, Issue:3 Topics: Analysis of Variance; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agents; Extinction, Psychological; In Vitro Techniques; Isradipine; Long-Term Potentiation; Male; Memory; Neurotransmitter Agents; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area	2016
The L-type calcium channel blocker, isradipine, attenuates cue-induced cocaine-seeking by enhancing dopaminergic activity in the ventral tegmental area to nucleus accumbens pathway. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:12 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cocaine; Cues; Dopamine; Drug-Seeking Behavior; Isradipine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area	2018
Harmony and heresy of an L-type calcium channel inhibitor: suppression of cocaine seeking via increased dopamine transmission in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:12 Topics: Calcium Channel Blockers; Calcium Channels, L-Type; Cocaine; Cues; Dopamine; Dopamine Uptake Inhibitors; Isradipine; Nucleus Accumbens; Ventral Tegmental Area	2018
Cocaine- and stress-primed reinstatement of drug-associated memories elicit differential behavioral and frontostriatal circuit activity patterns via recruitment of L-type Ca Molecular psychiatry, 2020, Volume: 25, Issue:10 Topics: Animals; Calcium Channels, L-Type; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Frontal Lobe; Isradipine; Male; Memory; Mice; Mice, Inbred C57BL; Neural Pathways; Nucleus Accumbens; Stress, Psychological	2020