cocaine has been researched along with haloperidol in 217 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (30.41) | 18.7374 |
| 1990's | 83 (38.25) | 18.2507 |
| 2000's | 49 (22.58) | 29.6817 |
| 2010's | 18 (8.29) | 24.3611 |
| 2020's | 1 (0.46) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Goodman, MM; Kabalka, GW; Kung, HF; Kung, MP; Switzer, R | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Hansch, C; Kurup, A; Mekapati, SB; Verma, RP | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Aricò, G; Cobos, EJ; Colabufo, NA; Contino, M; González, LG; Marrazzo, A; Marrazzo, G; Parenti, C; Pasquinucci, L; Prezzavento, O; Ronsisvalle, G; Ronsisvalle, S; Scoto, GM | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Dismukes, K; Mulder, AH | 1 |
| Aoi, W; Henry, DP; Weinberger, MH | 1 |
| Colpaert, FC; Janssen, PA; Niemegeers, CJ | 3 |
| Aulakh, CS; Bhattacharyya, AK; Ghosh, P; Pradhan, S; Pradhan, SN | 1 |
| Moerschbaecher, JM; Thompson, DM | 1 |
| Aulakh, CS; Ghosh, B; Pradhan, SN | 1 |
| Fahim, I; Ismail, M; Osman, OH | 1 |
| Hikasa, N; Otsuki, S; Sato, M | 1 |
| Altshuler, HL; Epstein, PN | 1 |
| Colpaert, FC | 1 |
| Hikasa, N; Otsuki, S; Sato, M; Suemaru, K; Tomoda, T | 1 |
| Ayhan, H; Papeschi, R; Theiss, P | 1 |
| Ilhan, M; Long, JP | 1 |
| Ozawa, H; Uematsu, T | 1 |
| Conde, M; Delgado, JM; Delgado-Garcia, JM; Robles, SS | 1 |
| Kahoun, JR; Ruoho, AE | 1 |
| Ding, XZ; Mocchetti, I | 1 |
| Koob, GF; Maldonado-Lopez, R; Robledo, P | 1 |
| Batsche, K; Granoff, MI; Wang, RY | 1 |
| Calder, LD; Karler, R | 1 |
| De Montis, G; Devoto, P; Tagliamonte, A | 1 |
| Carlen, PL; Jahromi, SS; Niesen, C | 1 |
| Borowsky, B; Kuhn, CM | 1 |
| Barbanel, G; Kamenka, JM; Maurice, T; Vignon, J | 1 |
| Cory-Slechta, DA; Widzowski, DV | 1 |
| Geyer, MA; Paulus, MP | 1 |
| Thompson, DM; Winsauer, PJ | 1 |
| Nambudiri, DE; Young, RC | 1 |
| Peltier, R; Schenk, S | 1 |
| Goldberg, SR; Schindler, CW; Tella, SR; Witkin, JM | 2 |
| Cabib, S; Castellano, C; Cestari, V; Filibeck, U; Puglisi-Allegra, S | 1 |
| Brewer, KW; Czachura, JF; Gonzalez, LP | 1 |
| Allard, P; Eriksson, K; Marcusson, JO; Ross, SB | 1 |
| Katz, JL; Witkin, JM | 1 |
| Appel, JB; Callahan, PM; Cunningham, KA | 1 |
| Kuribara, H; Tadokoro, S | 1 |
| Asami, T; Ida, I; Kuribara, H; Machiyama, Y; Tadokoro, S | 1 |
| Duckles, SP; Massamiri, T | 1 |
| Anthony, EW; Kleven, MS; Woolverton, WL | 1 |
| Albertson, TE; Derlet, RW; Rice, P | 1 |
| Kantak, KM; Lawley, SI | 2 |
| Loh, EA; Roberts, DC; Vickers, G | 1 |
| Kantak, KM | 1 |
| Goldberg, SR; Katz, JL; Witkin, JM | 1 |
| Broadley, KJ; Williamson, KL | 1 |
| Murman, D; Pert, A; Post, RM; Weiss, SR; Woodward, R | 1 |
| Jaffe, JH; Kumor, KM; Sherer, MA | 1 |
| Calder, LD; Chaudhry, IA; Karler, R; Turkanis, SA | 1 |
| Colpaert, FC; Kamenka, JM; Koek, W; Woods, JH | 1 |
| Calder, L; Karler, R; Petty, C; Turkanis, SA | 1 |
| De Vry, J; Donselaar, I; Van Ree, JM | 1 |
| Glen, KA; Kuhar, MJ; Sharkey, J; Wolfe, S | 1 |
| Jaffe, J; Kumor, K; Sherer, M | 1 |
| Bergman, J; Spealman, RD | 1 |
| Cubeddu, LX; Hoffmann, IS; Talmaciu, RK | 1 |
| Arbilla, S; Baud, P; Langer, SZ | 1 |
| Wessinger, WD | 1 |
| Roberts, DC; Vickers, G | 1 |
| Seifert, WF; van Ree, JM; van Wolfswinkel, L | 1 |
| Ilarionov, I | 1 |
| Sherer, MA | 1 |
| Dalton, JC; Roberts, DC; Vickers, GJ | 2 |
| Nomikos, GG; Spyraki, C; Varonos, DD | 1 |
| Funk, KF; Schmidt, J; Westermann, KH | 1 |
| Kokkinidis, L | 1 |
| Huang, D; Wilson, MC | 2 |
| Boselli, C; Chiari, MC; Grana, E; Lucchelli, A | 1 |
| Russell, RD; Stripling, JS | 1 |
| Georgi, H; Gey, KF | 1 |
| Hamilton, TC | 1 |
| Aihara, H; Kasai, A; Sakai, T | 1 |
| Gajda, L; Grabowska, M; Maj, J | 1 |
| Ueda, S | 1 |
| Järbe, TU | 1 |
| Miczek, KA; Yoshimura, H | 1 |
| Brake, SC; Spear, LP | 1 |
| Appel, JB; Holohean, AM; White, FJ | 1 |
| Schmidt, J; Westermann, KH | 1 |
| Fibiger, HC; Phillips, AG; Spyraki, C | 1 |
| Clarke, DE; Miller, HH; Shore, PA | 1 |
| de la Garza, R; Johanson, CE | 1 |
| Lal, H; Shearman, GT | 1 |
| Hertting, G; Hoffmann, I; Jackisch, R; Starke, K; Zumstein, A | 1 |
| Heffner, TG; Stricker, EM; Zigmond, MJ | 1 |
| Balster, RL; Woolverton, WL | 1 |
| Hikasa, N; Otsuki, S; Sato, M; Tomoda, T | 1 |
| Daras, M; Kakkouras, L; Koppel, BS; Tuchman, AJ | 1 |
| Carlson, S; Grönroos, M; Linnankoski, I; Pertovaara, A | 1 |
| Henderson, MG; McMillen, BA | 1 |
| Christensen, JR; Flory, GS; Miller, DW; Rebec, GV; White, IM | 1 |
| Misawa, M; Mori, T; Suzuki, T; Tsuji, M | 1 |
| Misawa, M; Suzuki, T | 1 |
| Gauvin, DV; Goulden, KL; Holloway, FA | 1 |
| Kling-Petersen, T; Ljung, E; Svensson, K | 1 |
| Martin-Iverson, MT; Reimer, AR | 2 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Ramamoorthy, JD; Ramamoorthy, S | 1 |
| LeDuc, PA; Mittleman, G | 1 |
| Bedingfield, JB; Calder, LD; Karler, R | 1 |
| Gibb, JW; Gygi, SP; Hanson, GR | 1 |
| Richardson, NR; Roberts, DC; Smith, AM | 1 |
| Corrigall, WA; Higgins, GA; Joharchi, N; Sellers, EM; Wang, Y | 1 |
| Damato, AN; Getsos, JP; Moussa, G; Patel, A | 1 |
| Tella, SR | 1 |
| Kameyama, T; Mori, E; Ukai, M | 1 |
| Altura, BM; Altura, BT; He, GQ; Zhang, A | 1 |
| Kelly, G; Trippenbach, T | 1 |
| Callahan, PM; Cunningham, KA | 1 |
| Nantwi, KD; Schoener, EP | 1 |
| Gamble, G; Greenstein, RA; McLellan, AT; Stone, AM | 1 |
| Justice, JB; Olson, RJ | 1 |
| Marsden, CA; McCreary, AC | 1 |
| Rapoza, D | 1 |
| Berger, SP; Carr, K; Crawford, CA; Delucchi, K; Hall, S; Mickalian, JD; Reid, MS | 1 |
| Geter-Douglass, B; Riley, AL | 1 |
| Mizuki, Y; Ushijima, I; Yamada, M | 1 |
| Ellison, T; Mattingly, BA; Rase, K; Rowlett, JK | 1 |
| Baker, I; Masserano, JM; Natsukari, N; Wyatt, RJ | 1 |
| Graybiel, AM; Moratalla, R; Tonegawa, S; Xu, M | 1 |
| DeCaprio, JL; Kosten, TA; Nestler, EJ | 1 |
| Bozarth, MA; Pudiak, CM | 1 |
| Aerts, N; Clincke, G; De Haes, P; Meert, TF | 1 |
| Dhopesh, V; Gamble, G; Maany, I; Macfadden, A | 1 |
| Johnson, PI; Napier, TC | 1 |
| Kosten, TA | 1 |
| Fujiwara, T; Funaki, Y; Hishinuma, T; Ido, T; Ishiwata, S; Itoh, M; Iwata, R; Mizugaki, M; Nakamura, H; Numachi, Y; Sato, M; Tomioka, Y; Yanai, K; Yoshida, S | 1 |
| Castagnoli, N; Dormehl, IC; Hugo, N; Keeve, R; Müller-Gärtner, HW; Neumeyer, JL; Oliver, DW; Rossouw, NT; Van der Schyf, CJ | 1 |
| Bittencourt, AL; Takahashi, RN | 1 |
| Baird, TJ; Briscoe, RJ; Carl, KL; Gauvin, DV; Holloway, FA; Vallett, M | 1 |
| Choi, SJ; Ngong, JM; Park, KK; Soliman, KF; Yoon, KJ | 1 |
| Areso, MP; García-Vallejo, P; Giralt, MT; Gómez, FM; Sainz, B | 1 |
| Akimoto, T; Mizuki, Y; Suetsugi, M; Ushijima, I; Yamada, M | 1 |
| Barnes, CA; Brothers, GM; Chidiac, P; Chung, S; Gilman, AG; Ingi, T; Krumins, AM; Lanahan, AA; Ross, EM; Siderovski, DP; Snow, BE; Worley, PF | 1 |
| Doubles, L; Rebec, GV; White, IM | 1 |
| Hashimoto, T; Kajii, Y; Nishikawa, T | 1 |
| Goeders, NE; Ikemoto, S | 1 |
| Glennon, RA; Young, R | 1 |
| Dow-Edwards, D; Shi, X; Yin, R | 1 |
| Corera, AT; Costentin, J; Deslandes, A; Vaugeois, JM | 1 |
| De Haes, P; Meert, TF; van Campenhout, N | 1 |
| Audinot, V; Brocco, M; Dekeyne, A; Despaux, N; Maiofiss, L; Millan, MJ; Newman-Tancredi, A; Peglion, JL; Queriaux, S; Rivet, JM | 1 |
| Duman, RS; Impey, S; Sakai, N; Shin, K; Steffen, C; Storm, D; Thome, J; Zhang, YJ | 1 |
| Carey, R; Damianopoulos, E; De Palma, G | 1 |
| Accili, D; Betancur, C; Cazillis, M; Fuchs, S; Lépée-Lorgeoux, I; Rostène, W | 1 |
| Aoki, T; Kobayashi, T; Mizuki, Y; Suetsugi, M; Usami, K; Ushijima, I; Watanabe, Y | 1 |
| Gessa, GL; Marchese, G; Pani, L; Ruiu, S; Saba, PL | 1 |
| Collins, SL; Edwards, MA; Kantak, KM | 1 |
| D'Souza, UM; Eisch, AJ; Hwang, CK; Kim, YM; Lammers, CH; Lee, SH; Mouradian, MM; Nestler, EJ; Yajima, S; Yang, Y | 1 |
| Adams, JU; Careri, JM; Efferen, TR; Rotrosen, J | 1 |
| Bushnell, PJ; Derr-Yellin, EC; Kodavanti, PR; MacPhail, RC; Moser, VC; Oshiro, WM; Phillips, PM | 1 |
| Ashby, CR; Gardner, EL; Hagan, JJ; Hayes, R; Liu, X; Middlemiss, DN; Paul, M; Stemp, G; Vorel, SR | 1 |
| Gál, K; Gyertyán, I | 1 |
| De Deurwaerdère, P; Moison, D; Porras, G; Spampinato, U | 1 |
| Boules, M; Fauq, A; McCormick, D; McMahon, B; Richelson, E; Stewart, J; Wang, R; Warrington, L; Yerbury, S | 1 |
| Cho, H; Cho, YS; Choi, KI; Jeong, D; Jung, JY; Jung, SH; Kim, GD; Koh, HY; Kong, JY; Lee, S; Pae, AN; Park, WK; Yun, CW | 1 |
| De Deurwaerdère, P; Navailles, S; Porras, G; Spampinato, U | 1 |
| Ito, S; Mori, T; Narita, M; Sawaguchi, T; Suzuki, T | 1 |
| France, CP; Koek, W; McMahon, LR; Sell, SL | 1 |
| Kuhn, CM; Ray, R; Walker, QD | 1 |
| Beardsley, PM; Newman, JL | 1 |
| Ayala, E; Chen, W; Coop, A; Daniels, A; Matsumoto, RR | 1 |
| Gomez, I; Gonzalez, S; Gonzalez-Hernandez, T; Gonzalez-Mora, JL; Morales, I; Rodriguez, M | 1 |
| Gerak, LR; Moerschbaecher, JM; Quinton, MS; Winsauer, PJ | 1 |
| Claytor, R; Martelle, JL; Nader, MA; Newman, AH; Reboussin, BA; Ross, JT | 1 |
| Caine, SB; Fink-Jensen, A; Thomsen, M; Wess, J; Woldbye, DP; Wörtwein, G | 1 |
| Alvarez, Jdo N; Chinen, CC; de Castro, JP; Frussa-Filho, R; Fukushiro, DF; Tatsu, JA | 1 |
| Haynes, JM; Pouton, CW; Raye, WS; Tochon-Danguy, N | 1 |
| Di Pietro, C; Golini, E; Mandillo, S; Marazziti, D; Matteoni, R; Tocchini-Valentini, GP | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Ito, S; Mori, T; Namiki, M; Sawaguchi, T; Suzuki, T | 1 |
| Moerschbaecher, JM; Roussell, AM; Winsauer, PJ | 1 |
| Bertran-Gonzalez, J; Bosch, C; Girault, JA; Hervé, D; Maroteaux, M; Matamales, M; Valjent, E | 1 |
| Bateup, HS; Gong, S; Greengard, P; Heintz, N; Kuroiwa, M; Nishi, A; Svenningsson, P | 1 |
| Alvarez, Jdo N; Carvalho, Rde C; Frussa-Filho, R; Fukushiro, DF; Ribeiro, LT; Ricardo, VP | 1 |
| Ginsburg, BC; Lamb, RJ; Pinkston, JW | 1 |
| Angelucci, F; Bernardi, G; Caltagirone, C; Cantarella, C; Castelli, M; Cavasinni, F; Centonze, D; De Chiara, V; Maccarrone, M; Mataluni, G; Musella, A; Napolitano, F; Rossi, S; Sacchetti, L; Usiello, A | 1 |
| Bateup, HS; Birnbaum, S; Fisone, G; Greengard, P; Nestler, EJ; Santini, E; Shen, W; Surmeier, DJ; Valjent, E | 1 |
| Banasikowski, TJ; Behl, B; Beninger, RJ; Bespalov, A; Drescher, K; Gross, G; Haupt, A; Schoemaker, H; Sullivan, JP; Unger, L | 1 |
| Oleson, EB; Richardson, JM; Roberts, DC | 1 |
| Horne, MK; Lee, J; Parish, CL; Tomas, D | 1 |
| Briscione, MA; Riley, AL; Serafine, KM | 1 |
| Carroll, FI; McMahon, LR; Schulze, DR | 1 |
| Bradaia, A; Bruns, A; Buchy, D; Chaboz, S; Galley, G; Groebke Zbinden, K; Hoener, MC; Kilduff, TS; Metzler, V; Morairty, SR; Moreau, JL; Mory, R; Norcross, RD; Pouzet, B; Revel, FG; Risterucci, C; Tuerck, D; Wallace, TL; Wettstein, JG | 1 |
| Dou, HQ; Kang, XJ; Kuo, ST; Li, Q; Sun, L; Wang, SR; Xu, HD; Yao, W; Zhang, B; Zhang, CX; Zhou, Z; Zuo, PL | 1 |
| Baldaia, MA; Berro, LF; Frussa-Filho, R; Hollais, AW; Longo, BM; Marinho, EA; Oliveira-Lima, AJ; Santos, R; Wuo-Silva, R | 1 |
| Akins, CK; Levi Bolin, B; Singleton, DL | 1 |
| Caraci, F; Cathala, A; Devroye, C; Di Marco, B; Drago, F; Piazza, PV; Spampinato, U | 1 |
| Borrelli, E; Caron, MG; Pack, TF; Payne, K; Peterson, SM; Rose, SJ | 1 |
| Makiguchi, A; Okada, T; Shioda, K; Suda, S | 1 |
1 review(s) available for cocaine and haloperidol
| Article | Year |
|---|---|
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Cocaine; Exploratory Behavior; Female; Haloperidol; Learning; Limbic System; Male; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Social Behavior | 1983 |
2 trial(s) available for cocaine and haloperidol
| Article | Year |
|---|---|
Effects of intravenous cocaine are partially attenuated by haloperidol.
Topics: Adult; Arousal; Blood Pressure; Brain; Clinical Trials as Topic; Cocaine; Double-Blind Method; Euphoria; Haloperidol; Heart Rate; Humans; Infusions, Intravenous; Injections, Intramuscular; Receptors, Dopamine | 1989 |
Haloperidol antagonism of cue-elicited cocaine craving.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Anxiety; Cocaine; Conditioning, Psychological; Cross-Over Studies; Cues; Double-Blind Method; Haloperidol; Homovanillic Acid; Humans; Hydrocortisone; Male; Psychological Tests; Substance-Related Disorders | 1996 |
214 other study(ies) available for cocaine and haloperidol
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tropanes | 1994 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
The role of QSAR in dopamine interactions.
Topics: Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, Dopamine D2; Receptors, Dopamine D4 | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Novel potent and selective σ ligands: evaluation of their agonist and antagonist properties.
Topics: Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Cyclopropanes; Drug Design; Humans; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Muscle Contraction; Piperidines; Protein Binding; Receptors, Opioid, delta; Time Factors | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Effects of neuroleptics on release of 3H-dopamine from slices of rat corpus striatum.
Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Fluphenazine; Haloperidol; Male; Rats; Spiperone | 1977 |
The effects of dopamine on renin release in vitro.
Topics: Animals; Ascorbic Acid; Cocaine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hydrazines; In Vitro Techniques; Juxtaglomerular Apparatus; Kidney; Male; Phentolamine; Propranolol; Rats; Renin | 1977 |
Neuroleptic interference with the cocaine cue: internal stimulus control of behavior and psychosis.
Topics: Amphetamine; Animals; Antipsychotic Agents; Behavior; Cocaine; Cues; Drug Interactions; Haloperidol; Humans; Male; Pimozide; Psychotic Disorders; Rats; Spiperone | 1978 |
Modification of behavioral and neurochemical effects of cocaine by haloperidol.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Drug Interactions; Haloperidol; Humans; Male; Motor Activity; Neurotransmitter Agents; Rats; Stereotyped Behavior; Time Factors | 1979 |
Operant methodology in the study of learning.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Drug Tolerance; Erythrocebus patas; Fenfluramine; Haloperidol; Haplorhini; Learning | 1978 |
Actions and interactions of cocaine on self-stimulation behavior in rats.
Topics: Animals; Azaperone; Cocaine; Drug Interactions; Haloperidol; Hypothalamus; Male; Rats; Scopolamine; Self Stimulation; Time Factors | 1979 |
Hypothermic effect of cocaine in rats.
Topics: Animals; Body Temperature; Chickens; Cocaine; Depression, Chemical; Female; Fenclonine; Goats; Haloperidol; Hydroxydopamines; Male; Methyltyrosines; Mice; Rabbits; Rats; Scopolamine; Time Factors | 1975 |
Experimental epilepsy, psychosis, and dopamine receptor sensitivity.
Topics: Amygdala; Animals; Apomorphine; Cats; Cocaine; Electric Stimulation; Evoked Potentials; Haloperidol; Receptors, Dopamine; Seizures | 1979 |
Altered response to apomorphine and haloperidol after nine days of cocaine injections.
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Cocaine; Drug Interactions; Haloperidol; Humans; Male; Rats; Stereotyped Behavior; Time Factors | 1979 |
Sensitization and desensitization to lateral hypothalamic stimulation.
Topics: Animals; Cocaine; Discrimination, Psychological; Electric Stimulation; Haloperidol; Hypothalamus; Rats | 1977 |
Discriminative stimulus properties of cocaine and d-amphetamine, and antagonism by haloperidol: a comparative study.
Topics: Animals; Cocaine; Dextroamphetamine; Discrimination, Psychological; Haloperidol; Male; Rats | 1978 |
Seizure development and dopamine receptor sensitivity.
Topics: Amygdala; Animals; Cats; Cocaine; Haloperidol; Receptors, Dopamine; Seizures | 1978 |
AMT catalepsy and hypokinesia: interaction with morphine and cocaine.
Topics: Animals; Body Temperature; Brain Chemistry; Catalepsy; Catecholamines; Cocaine; Drug Interactions; Drug Tolerance; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Psychomotor Disorders; Rats | 1976 |
Cocaine cue in rats as it relates to subjective drug effects: a preliminary report.
Topics: Amphetamine; Animals; Apomorphine; Cocaine; Conditioning, Operant; Cues; Cyproheptadine; Dibenzylchlorethamine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Haloperidol; Methysergide; Pimozide; Propranolol; Rats | 1976 |
Inhibition of the sympathetic nervous system by dopamine.
Topics: Animals; Autonomic Fibers, Postganglionic; Blood Pressure; Cats; Cocaine; Depression, Chemical; Dopamine; Electric Stimulation; Haloperidol; Heart Rate; Norepinephrine; Phenoxybenzamine; Phentolamine; Phenylephrine; Stimulation, Chemical; Sympathetic Nervous System | 1975 |
[Mode of action of clonidine, a central hypotensive agent, analyzed by the interaction with various sympathomimetic agents].
Topics: Animals; Blood Pressure; Central Nervous System; Chlorpromazine; Clonidine; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Ephedrine; Guanethidine; Guinea Pigs; Haloperidol; Hexamethonium Compounds; Imipramine; In Vitro Techniques; Male; Methamphetamine; Norepinephrine; Rats; Sympathomimetics; Tyramine; Vas Deferens | 1975 |
Fatigability of caudate nucleus stimulation in cats.
Topics: Animals; Catecholamines; Cats; Caudate Nucleus; Cocaine; Differential Threshold; Electric Stimulation; Electrophysiology; Eye Movements; Habituation, Psychophysiologic; Haloperidol; Imipramine; Motor Activity; Movement; Orientation; Reserpine; Time Factors | 1976 |
(125I)iodoazidococaine, a photoaffinity label for the haloperidol-sensitive sigma receptor.
Topics: Affinity Labels; Animals; Binding, Competitive; Biogenic Amines; Biological Transport; Brain; Carrier Proteins; Cell Membrane; Cocaine; Haloperidol; Humans; Liver; Microsomes, Liver; Photochemistry; Placenta; Rats; Receptors, Opioid; Receptors, sigma | 1992 |
Dopaminergic regulation of cholecystokinin mRNA content in rat striatum.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benztropine; Blotting, Northern; Brain; Cerebral Cortex; Cholecystokinin; Cocaine; Corpus Striatum; Dopamine; Haloperidol; Kinetics; Male; Mesencephalon; Organ Specificity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; RNA, Messenger | 1992 |
Role of dopamine receptors in the nucleus accumbens in the rewarding properties of cocaine.
Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Haloperidol; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement, Psychology; Reward; Self Administration | 1992 |
5-HT3 receptor antagonists fail to block the suppressant effect of cocaine on the firing rate of A10 dopamine neurons in the rat.
Topics: Animals; Cocaine; Dopamine; Electrophysiology; Haloperidol; Male; Neurons; Rats; Rats, Sprague-Dawley; Salicylamides; Serotonin Antagonists | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Failure by tricyclic antidepressants to affect the increase of dopamine extracellular concentrations produced by haloperidol in the caudate and accumbens nuclei of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Caudate Nucleus; Cocaine; Dopamine; Drug Interactions; Haloperidol; Imipramine; Male; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains | 1992 |
Amphetamine actions on pre- and postpubertal rat hippocampal dentate granule neurons.
Topics: Aging; Animals; Atenolol; Calcium Channels; Cocaine; Dextroamphetamine; Evoked Potentials; Haloperidol; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Sexual Maturation; Synapses | 1991 |
Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation.
Topics: Adrenocorticotropic Hormone; Animals; Biogenic Monoamines; Cocaine; Corticosterone; Dopamine; Dopamine Antagonists; Haloperidol; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Ketanserin; Male; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Piperazines; Pituitary-Adrenal System; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stimulation, Chemical; Time Factors | 1991 |
Modulation by dopamine of [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP, a phencyclidine derivative) binding to the dopamine uptake complex.
Topics: alpha-Methyltyrosine; Animals; Benserazide; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Haloperidol; In Vitro Techniques; Levodopa; Male; Membrane Proteins; Methyltyrosines; Mice; Nerve Tissue Proteins; Phencyclidine; Piperazines; Rats; Reserpine | 1991 |
Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Cocaine; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Dopamine Agents; Drug Synergism; Ergolines; Generalization, Psychological; Haloperidol; Lead; Male; Morphine; N-Methylaspartate; Pentobarbital; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
A scaling approach to find order parameters quantifying the effects of dopaminergic agents on unconditioned motor activity in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Cocaine; Dextroamphetamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Ergolines; Haloperidol; Motor Activity; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Yawning | 1991 |
Cocaine self-administration in pigeons.
Topics: Animals; Cocaine; Columbidae; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Food; Haloperidol; Male; Reinforcement Schedule; Self Administration | 1991 |
A case of late-onset crack dependence and subsequent psychosis in the elderly.
Topics: Crack Cocaine; Delusions; Hallucinations; Haloperidol; Humans; Male; Middle Aged; Psychoses, Substance-Induced; Substance-Related Disorders | 1991 |
GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Injections, Intravenous; Male; Ondansetron; Rats; Rats, Inbred Strains; Self Administration; Serotonin Antagonists | 1991 |
Interaction of haloperidol and SCH 23390 with cocaine and dopamine receptor subtype-selective agonists on schedule-controlled behavior of squirrel monkeys.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Ergolines; Female; Haloperidol; Male; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement Schedule; Saimiri | 1991 |
D1 and D2 receptor antagonists differently affect cocaine-induced locomotor hyperactivity in the mouse.
Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Metoclopramide; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Dopamine D1; Receptors, Dopamine D2; Stimulation, Chemical; Sulpiride | 1991 |
Chronic cocaine-induced supersensitivity id blocked by co-treatment with the peptide cyclo-(Leu-Gly).
Topics: Animals; Body Temperature; Catalepsy; Cocaine; Haloperidol; Motor Activity; Neuropeptides; Peptides, Cyclic; Rats; Stereotyped Behavior | 1990 |
Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs.
Topics: Animals; Binding, Competitive; Bromocriptine; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Haloperidol; Kinetics; Male; Piperazines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides | 1990 |
Behavioral effects of cocaine alone and in combination with selective dopamine antagonists in the squirrel monkey.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Haloperidol; Regression Analysis; Reinforcement Schedule; Saimiri | 1991 |
Dopamine D1 and D2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cocaine; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Ergolines; Generalization, Psychological; Haloperidol; Male; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1991 |
Effects of cocaine alone and in combination with haloperidol and SCH 23390 on cardiovascular function in squirrel monkeys.
Topics: Animals; Benzazepines; Cocaine; Drug Antagonism; Haloperidol; Heart; Hemodynamics; Male; Receptors, Dopamine; Saimiri | 1991 |
The ambulation-increasing effect of buprenorphine in mice: comparison with the effect of morphine.
Topics: Animals; Buprenorphine; Caffeine; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Locomotion; Male; Methamphetamine; Mice; Morphine; Naloxone; Pilocarpine; Scopolamine | 1991 |
[Characteristics of antagonism between ceruletide and various central-acting drugs: investigation by means of ambulatory activity in mice].
Topics: Animals; Bromocriptine; Caffeine; Ceruletide; Cocaine; Dose-Response Relationship, Drug; Drug Tolerance; Ephedrine; Haloperidol; Male; Methamphetamine; Methylphenidate; Mice; Morphine; Motor Activity; Scopolamine | 1990 |
Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.
Topics: Animals; Cocaine; Desoxycorticosterone; Haloperidol; Male; Norepinephrine; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Serotonin; Vasoconstriction | 1990 |
Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys.
Topics: Animals; Benzazepines; Cocaine; Dextroamphetamine; Discrimination Learning; Female; Haloperidol; Macaca mulatta; Male; Piperazines; Receptors, Dopamine | 1990 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Haloperidol; Lethal Dose 50; Male; Methamphetamine; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Seizures | 1990 |
Postconditioning effects of magnesium on cocaine conditioned place preference in mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dextroamphetamine; Generalization, Stimulus; Haloperidol; Magnesium; Male; Mice; Pentobarbital; Reinforcement, Psychology | 1990 |
Magnesium-induced conditioned place preference in mice.
Topics: Animals; Cocaine; Conditioning, Psychological; Dextroamphetamine; Generalization, Stimulus; Haloperidol; Magnesium; Male; Mice; Pentobarbital; Reinforcement, Psychology; Time Factors | 1990 |
Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Inbred Strains; Reinforcement Schedule; Self Administration | 1989 |
Magnesium alters the potency of cocaine and haloperidol on mouse aggression.
Topics: Aggression; Animals; Cocaine; Diet; Dose-Response Relationship, Drug; Drug Synergism; Female; Haloperidol; Magnesium; Magnesium Deficiency; Male; Mice; Motor Activity; Time Factors | 1989 |
Lethal effects of cocaine are reduced by the dopamine-1 receptor antagonist SCH 23390 but not by haloperidol.
Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, Dopamine D1 | 1989 |
Do both adrenaline and noradrenaline stimulate cardiac alpha-adrenoceptors to induce positive inotropy of rat atria?
Topics: Animals; Cocaine; Desipramine; Dibenzylchlorethamine; Epinephrine; Haloperidol; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Norepinephrine; Pindolol; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Stimulation, Chemical; Timolol | 1989 |
Context-dependent cocaine sensitization: differential effect of haloperidol on development versus expression.
Topics: Animals; Behavior, Animal; Cocaine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Homing Behavior; Male; Motor Activity; Rats; Rats, Inbred Strains | 1989 |
Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801.
Topics: Amphetamine; Animals; Anticonvulsants; Cocaine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Haloperidol; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1989 |
The phencyclidine (PCP) analog N-[1-(2-benzo(B)thiophenyl) cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801.
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dextroamphetamine; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Haloperidol; Ketamine; Methylphenidate; Mice; Phencyclidine; Rats; Seizures; Structure-Activity Relationship | 1989 |
Proconvulsant and anticonvulsant effects in mice of acute and chronic treatment with cocaine.
Topics: Amphetamine; Animals; Anticonvulsants; Cocaine; Convulsants; Dose-Response Relationship, Drug; Electric Stimulation; Haloperidol; Kindling, Neurologic; Male; Mice; Motor Activity; Time Factors | 1989 |
Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.
Topics: Animals; Body Weight; Cocaine; Food Deprivation; Haloperidol; Male; Naltrexone; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration | 1989 |
Cocaine binding at sigma receptors.
Topics: Animals; Binding, Competitive; Cerebellum; Cocaine; Haloperidol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1988 |
Haloperidol-induced dystonia in cocaine addicts.
Topics: Adult; Cocaine; Dystonia; Haloperidol; Humans; Male; Substance-Related Disorders | 1986 |
Behavioral effects of histamine H1 antagonists: comparison with other drugs and modification by haloperidol.
Topics: Animals; Bupropion; Cocaine; Conditioning, Operant; Cyproheptadine; Desipramine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Haloperidol; Histamine H1 Antagonists; Male; Propiophenones; Saimiri | 1988 |
Interactions between endogenous dopamine and dopamine agonists at release modulatory receptors: multiple effects of neuronal uptake inhibitors on transmitter release.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Apomorphine; Bromocriptine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Ergolines; Haloperidol; In Vitro Techniques; Methyltyrosines; Neurotransmitter Uptake Inhibitors; Nomifensine; Quinpirole; Rabbits; Receptors, Dopamine; Reserpine | 1986 |
Inhibition of the electrically evoked release of [3H]acetylcholine in rat striatal slices: an experimental model for drugs that enhance dopaminergic neurotransmission.
Topics: Acetylcholine; Amphetamine; Animals; Chlorpromazine; Clozapine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; Male; Nomifensine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Synaptic Transmission | 1985 |
Approaches to the study of drug interactions in behavioral pharmacology.
Topics: Alkaloids; Animals; Behavior, Animal; Brain; Chloral Hydrate; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Haloperidol; Humans; Phencyclidine; Phenobarbital; Synaptic Transmission | 1986 |
The effect of haloperidol on cocaine self-administration is augmented with repeated administrations.
Topics: Animals; Cocaine; Haloperidol; Male; Rats; Rats, Inbred Strains; Self Administration | 1987 |
Catecholamines and endogenous opioids in ventral tegmental self-stimulation reward.
Topics: Animals; Catecholamines; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Haloperidol; Male; Mesencephalon; Naloxone; Rats; Rats, Inbred Strains; Reward; Self Stimulation | 1988 |
[Pharmacologic studies of a tetrahydroxazine derivative].
Topics: Amphetamine; Anesthetics, Local; Animals; Appetite; Appetite Depressants; Behavior, Animal; Cocaine; Haloperidol; Imipramine; Morpholines; Motor Activity; Phenmetrazine; Propiophenones; Rats; Rats, Inbred Strains; Reserpine | 1988 |
Intravenous cocaine: psychiatric effects, biological mechanisms.
Topics: Adult; Arousal; Brain; Chromatography, High Pressure Liquid; Cocaine; Dose-Response Relationship, Drug; Euphoria; Haloperidol; Homovanillic Acid; Humans; Infusions, Intravenous; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Premedication; Psychoses, Substance-Induced; Substance-Related Disorders | 1988 |
Increased self-administration of cocaine following haloperidol: effect of ovariectomy, estrogen replacement, and estrous cycle.
Topics: Animals; Cocaine; Estrogens; Estrus; Female; Gonadal Steroid Hormones; Haloperidol; Ovariectomy; Ovary; Rats; Rats, Inbred Strains; Self Administration | 1987 |
Intravenous cocaine-induced place preference: attenuation by haloperidol.
Topics: Animals; Cocaine; Conditioning, Psychological; Haloperidol; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Reward | 1987 |
[Biochemical characterization and differentiation of dopaminergic supersensitivity in the rat].
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cocaine; Dopamine; Haloperidol; Muscle Denervation; Rats; Receptors, Dopamine; Reserpine; Synaptosomes | 1986 |
Increased self-administration of cocaine following haloperidol: sex-dependent effects of the antiestrogen tamoxifen.
Topics: Animals; Behavior, Animal; Cocaine; Female; Gonadal Steroid Hormones; Haloperidol; Male; Rats; Rats, Inbred Strains; Sex; Tamoxifen | 1986 |
Sensitization to amphetamine and tolerance to cocaine and phencyclidine stimulation in mice.
Topics: Animals; Cocaine; Dextroamphetamine; Drug Resistance; Drug Tolerance; Habituation, Psychophysiologic; Haloperidol; Mice; Phencyclidine; Reflex, Startle | 1986 |
Comparative discriminative stimulus properties of dl-cathinone, d-amphetamine, and cocaine in rats.
Topics: Alkaloids; Animals; Cocaine; Dextroamphetamine; Discrimination, Psychological; Dopamine; Haloperidol; Male; Psychotropic Drugs; Rats; Rats, Inbred Strains | 1986 |
Analysis of the relaxing effect of dopamine on the isolated rat jejunum.
Topics: Animals; Cocaine; Dopamine; Flupenthixol; Haloperidol; In Vitro Techniques; Jejunum; Male; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Tyramine | 1986 |
Monoaminergic and local anesthetic components of cocaine's effects on kindled seizure expression.
Topics: Amphetamine; Anesthetics, Local; Animals; Biogenic Amines; Cocaine; Drug Interactions; Haloperidol; Kindling, Neurologic; Lidocaine; Male; Metergoline; Prazosin; Propranolol; Rats; Seizures; Yohimbine | 1985 |
Effect of neurotropic agents on total pyridoxal phosphate and on the activity of the decarboxylose of aromatic amino acids as well as of other pyridoxal phosphate-dependent enzymes in rat brains.
Topics: Acetates; Amphetamine; Animals; Anti-Anxiety Agents; Atropine; Benzodiazepines; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chloroform; Chlorpromazine; Cocaine; Dihydroxyphenylalanine; Ether; Female; Glutamates; Haloperidol; Hydroxylamines; Methylphenidate; Oxotremorine; Pentobarbital; Pentylenetetrazole; Pyridoxal Phosphate; Quinolines; Rats; Reserpine; Scopolamine; Semicarbazides; Theophylline; Tranylcypromine; Tyrosine Transaminase | 1974 |
Effects of dopamine on the conductance of perfused vascular beds of the chloralosed cat.
Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cats; Cocaine; Constriction; Desipramine; Dilatation; Dopamine; Dopamine Antagonists; Drug Synergism; Female; Haloperidol; Heart Rate; Hindlimb; Histamine H1 Antagonists; Isoproterenol; Male; Perfusion; Phenoxybenzamine; Propranolol; Receptors, Adrenergic; Vascular Resistance | 1972 |
The effect of dopamine on peripheral vasculature of the rat.
Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine | 1972 |
Effect of apomorphine on motility in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Benzyl Compounds; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Esters; Fluorine; Haloperidol; Hydrazines; Male; Motor Activity; Nialamide; Nortriptyline; Phenoxybenzamine; Rats; Rats, Inbred Strains; Reserpine; Serine; Spiro Compounds; Stimulation, Chemical; Thiocarbamates; Tranquilizing Agents; Tyrosine | 1972 |
[Pharmacological responses of the pyloric antrum strip of the rat stomach, with special reference to the mechanism of the contractions caused by serotonin and nicotine, relaxation of transmural stimulation and contraction and relaxation by tyramine].
Topics: Acetylcholine; Animals; Atropine; Barium; Bretylium Compounds; Cocaine; Depression, Chemical; Dibenzylchlorethamine; Haloperidol; In Vitro Techniques; Methysergide; Morphine; Muscle Contraction; Nicotine; Phenoxybenzamine; Physostigmine; Procaine; Propranolol; Pylorus; Rats; Receptors, Drug; Scopolamine; Serotonin; Stimulation, Chemical; Tyramine | 1971 |
Discriminative stimulus properties of cocaine. Effects of apomorphine, haloperidol, procaine and other drugs.
Topics: Animals; Apomorphine; Cocaine; Columbidae; Cues; Discrimination Learning; Dronabinol; Generalization, Stimulus; Haloperidol; Lysergic Acid Diethylamide; Male; Pentobarbital; Procaine | 1984 |
Disruption of primate social behavior by d-amphetamine and cocaine: differential antagonism by antipsychotics.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Cocaine; Dextroamphetamine; Haloperidol; Humans; Male; Motor Activity; Physostigmine; Saimiri; Social Behavior; Stereotyped Behavior | 1982 |
Antagonism of a behavioral effect of LSD and lisuride in the cat.
Topics: Animals; Cats; Cocaine; Drug Antagonism; Ergolines; Female; Haloperidol; Lisuride; Lysergic Acid Diethylamide; Motor Activity; Pizotyline; Reflex | 1983 |
[Dopamine sensitivity of brain-induced behavior after repeated administration of dopamine agonists and antagonists].
Topics: Amphetamine; Animals; Apomorphine; Brain; Cocaine; Dopamine; Dopamine Antagonists; Female; Haloperidol; Motor Activity; Organ Specificity; Rats; Rats, Inbred Strains; Rotation | 1984 |
The effects of dl-cathinone, d-amphetamine and cocaine on avoidance responding in rats and their interactions with haloperidol and methysergide.
Topics: Alkaloids; Animals; Avoidance Learning; Catecholamines; Cocaine; Dextroamphetamine; Dopamine; Drug Interactions; Haloperidol; Male; Methysergide; Psychotropic Drugs; Rats; Rats, Inbred Strains | 1984 |
Cocaine-induced place preference conditioning: lack of effects of neuroleptics and 6-hydroxydopamine lesions.
Topics: Animals; Choice Behavior; Cocaine; Conditioning, Operant; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Hydroxydopamines; Male; Motor Activity; Norepinephrine; Nucleus Accumbens; Orientation; Oxidopamine; Pimozide; Procaine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reinforcement Schedule | 1982 |
In vivo monoamine oxidase inhibition by d-amphetamine.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Cocaine; Corpus Striatum; Dextroamphetamine; Haloperidol; Male; Monoamine Oxidase Inhibitors; Phenelzine; Rats | 1980 |
Effects of haloperidol and physostigmine on self-administration of local anesthetics.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Haloperidol; Macaca mulatta; Male; Physostigmine; Procaine; Receptors, Cholinergic; Reinforcement Schedule; Self Administration | 1982 |
Discriminative stimulus properties of cocaine related to an anxiogenic action.
Topics: Animals; Anxiety; Cocaine; Diazepam; Discrimination, Psychological; Haloperidol; Humans; Male; Pentylenetetrazole; Rats | 1981 |
Modulation by endogenous dopamine of the release of acetylcholine in the caudate nucleus of the rabbit.
Topics: Acetylcholine; Animals; Apomorphine; Bretylium Tosylate; Caudate Nucleus; Cocaine; Dopamine; Electric Stimulation; Haloperidol; Nomifensine; Potassium; Rabbits | 1980 |
The effect of altered dopaminergic activity on food intake in the rat: evidence for an optimal level of dopaminergic activity for behavior.
Topics: Amphetamine; Amphetamines; Animals; Apomorphine; Brain; Cocaine; Dextroamphetamine; Dopamine; Feeding Behavior; Haloperidol; Levodopa; Methylphenidate; Rats; Spiperone | 1980 |
Effects of antipsychotic compounds in rhesus monkeys given a choice between cocaine and food.
Topics: Animals; Chlorpromazine; Choice Behavior; Cocaine; Dose-Response Relationship, Drug; Eating; Haloperidol; Macaca mulatta; Male; Reinforcement, Psychology | 1981 |
Inhibition of amygdaloid kindling by chronic pretreatment with cocaine or methamphetamine.
Topics: Amygdala; Animals; Apomorphine; Cats; Cocaine; Electric Stimulation; Evoked Potentials; Haloperidol; Methamphetamine; Pimozide; Receptors, Dopamine; Seizures | 1980 |
Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome?
Topics: Adult; Antipsychotic Agents; Brain; Cell Death; Cocaine; Diagnosis, Differential; Diazepam; Female; Fever; Haloperidol; Humans; Male; Mental Disorders; Middle Aged; Muscles; Neuroleptic Malignant Syndrome; Rhabdomyolysis; Substance Abuse, Intravenous | 1995 |
Effect of cocaine on sexual behaviour in male stumptail macaques (Macaca arctoides).
Topics: Animals; Cocaine; Depression, Chemical; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ejaculation; Female; Haloperidol; Macaca; Male; Sexual Behavior, Animal | 1995 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain; Catalepsy; Cocaine; Corpus Striatum; Dopamine; Female; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Male; Nalidixic Acid; Naphthyridines; Organ Specificity; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin | 1993 |
Amphetamine, cocaine, and dizocilpine enhance performance on a lever-release, conditioned avoidance response task in rats.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1995 |
Interaction between discriminative stimulus effects of cocaine and morphine.
Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Morphine; Naloxone; Rats; Rats, Inbred F344; Synaptic Transmission | 1995 |
Sertindole antagonizes morphine-, cocaine-, and methamphetamine-induced place preference in the rat.
Topics: Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Fluphenazine; Haloperidol; Imidazoles; Indoles; Male; Methamphetamine; Morphine; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Spatial Behavior | 1995 |
A three-choice haloperidol-saline-cocaine drug discrimination task in rats.
Topics: Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Stimulus; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule | 1994 |
The preferential dopamine autoreceptor antagonist (+)-UH232 antagonizes the positive reinforcing effects of cocaine and d-amphetamine in the ICSS paradigm.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cocaine; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes; Haloperidol; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Stimulation | 1994 |
Effects of nimodipine and/or haloperidol on the expression of conditioned locomotion and sensitization to cocaine in rats.
Topics: Animals; Calcium Channels; Cocaine; Conditioning, Operant; Haloperidol; Male; Motor Activity; Nimodipine; Rats; Rats, Sprague-Dawley | 1994 |
Nimodipine and haloperidol attenuate behavioural sensitization to cocaine but only nimodipine blocks the establishment of conditioned locomotion induced by cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Nimodipine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1994 |
Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.
Topics: Choriocarcinoma; Cocaine; Female; Giant Cells; Gonadal Steroid Hormones; Haloperidol; Humans; Ligands; Neuropeptide Y; Phenytoin; Placenta; Pregnancy; Receptors, sigma; Trophoblasts; Tumor Cells, Cultured; Uterine Neoplasms | 1995 |
Interactions between chronic haloperidol treatment and cocaine in rats: an animal model of intermittent cocaine use in neuroleptic treated populations.
Topics: Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Motor Activity; Rats; Receptors, Presynaptic; Stereotyped Behavior; Substance-Related Disorders | 1993 |
Cocaine behavioral sensitization and the excitatory amino acids.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acids; Glutamic Acid; Haloperidol; Male; Mice; Neuroeffector Junction; Receptors, GABA-A; Seizures; Stereotyped Behavior | 1994 |
Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Cocaine; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Extrapyramidal Tracts; Globus Pallidus; Hallucinogens; Haloperidol; Limbic System; Male; Methamphetamine; Neurotensin; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1994 |
A single injection of either flupenthixol decanoate or haloperidol decanoate produces long-term changes in cocaine self-administration in rats.
Topics: Animals; Cocaine; Flupenthixol; Haloperidol; Injections, Intramuscular; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Substance-Related Disorders; Tranquilizing Agents | 1994 |
The CCKA receptor antagonist devazepide does not modify opioid self-administration or drug discrimination: comparison with the dopamine antagonist haloperidol.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Cocaine; Conditioning, Operant; Cues; Devazepide; Discrimination, Psychological; Dopamine Antagonists; Food; Haloperidol; Heroin; Male; Morphine; Narcotics; Phenylurea Compounds; Rats; Rats, Wistar; Receptors, Cholecystokinin; Self Administration | 1994 |
The Osborn wave of hypothermia in normothermic patients.
Topics: Adult; Aged; Angina Pectoris; Body Temperature; Chest Pain; Cocaine; Electrocardiography; Female; Haloperidol; Humans; Hypertension; Hypertrophy, Left Ventricular; Hypothermia; Male; Middle Aged; Myocardial Infarction; Substance-Related Disorders | 1994 |
Differential blockade of chronic versus acute effects of intravenous cocaine by dopamine receptor antagonists.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereotyped Behavior | 1994 |
Discriminative stimulus properties of cocaine in the rat using a two-choice discrete-trial avoidance paradigm.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Avoidance Learning; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Agents; Dose-Response Relationship, Drug; Electroshock; Ergolines; Haloperidol; Male; Methamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Quinpirole; Rats; Sulpiride | 1993 |
Cocaine-induced cerebrovasospasm and its possible mechanism of action.
Topics: Animals; Biological Transport; Brain; Calcium; Cells, Cultured; Cocaine; Cyclooxygenase Inhibitors; Dogs; Dopamine; Dopamine Antagonists; Eicosanoids; Female; Haloperidol; Indomethacin; Ischemic Attack, Transient; Male; Muscle Contraction; Sheep; Swine; Verapamil | 1994 |
Effects of acute and chronic cocaine on breathing and chemosensitivity in awake rats.
Topics: Animals; Cocaine; Haloperidol; Hypercapnia; Hypoxia; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Respiration; Time Factors | 1994 |
Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats.
Topics: Animals; Bromocriptine; Cocaine; Discrimination Learning; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 1993 |
Cocaine and dopaminergic actions in rat neostriatum.
Topics: Animals; Benzazepines; Cocaine; Depression, Chemical; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Infusions, Intravenous; Levodopa; Male; Neostriatum; Neurons; Procaine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1993 |
Cocaine use by schizophrenic outpatients who receive depot neuroleptic medication.
Topics: Adult; Ambulatory Care; Chronic Disease; Cocaine; Combined Modality Therapy; Comorbidity; Delayed-Action Preparations; Fluphenazine; Haloperidol; Humans; Injections, Intramuscular; Middle Aged; Schizophrenia; Schizophrenic Psychology; Substance Abuse Detection; Substance-Related Disorders; Veterans | 1993 |
Quantitative microdialysis under transient conditions.
Topics: Amphetamine; Animals; Cocaine; Dialysis; Dopamine; Extracellular Space; Haloperidol; Male; Microchemistry; Rats; Rats, Wistar | 1993 |
Cocaine-induced behaviour: dopamine D1 receptor antagonism by SCH 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine.
Topics: Amphetamine; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Haloperidol; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1993 |
Buspirone fails to affect the discriminative stimulus effects of cocaine.
Topics: Animals; Buspirone; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley | 1993 |
Dopamine D1/D2 antagonist combinations as antagonists of the discriminative stimulus effects of cocaine.
Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Female; Haloperidol; Rats; Receptors, Dopamine D1 | 1996 |
Alteration of cataleptic responses induced by dopamine receptor antagonists after chronic cocaine administration in mice.
Topics: Animals; Benzazepines; Catalepsy; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice | 1995 |
Cocaine-induced behavioral sensitization: effects of haloperidol and SCH 23390 treatments.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Antagonists; Haloperidol; Locomotion; Male; Rats; Rats, Wistar; Time Factors | 1996 |
Chronic cocaine administration increases tyrosine hydroxylase activity in the ventral tegmental area through glutaminergic- and dopaminergic D2-receptor mechanisms.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glutamate; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 1996 |
Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor.
Topics: Amphetamine; Animals; Antipsychotic Agents; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Gene Deletion; Haloperidol; Male; Mice; Mice, Mutant Strains; Psychomotor Performance; Receptors, Dopamine D1 | 1996 |
Long-term haloperidol administration enhances and short-term administration attenuates the behavioral effects of cocaine in a place conditioning procedure.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dogs; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Rats; Rats, Sprague-Dawley | 1996 |
Nitric oxide synthesis inhibition attenuates haloperidol-induced supersensitivity.
Topics: Animals; Antipsychotic Agents; Cocaine; Drug Hypersensitivity; Drug Synergism; Haloperidol; Locomotion; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 1997 |
Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist.
Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine D1 | 1996 |
Absence of parkinsonism among patients in long-term neuroleptic therapy who abuse cocaine.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Cocaine; Comorbidity; Delayed-Action Preparations; Fluphenazine; Haloperidol; Humans; Long-Term Care; Male; Middle Aged; Neurologic Examination; Opioid-Related Disorders; Parkinson Disease, Secondary; Receptors, Dopamine; Risk Factors; Schizophrenia | 1997 |
Contribution of the nucleus accumbens to cocaine-induced responses of ventral pallidal neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Globus Pallidus; Haloperidol; Injections, Intravenous; Male; Microinjections; Narcotics; Neurons; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley | 1996 |
Enhanced neurobehavioral effects of cocaine with chronic neuroleptic exposure in rats.
Topics: Animals; Antipsychotic Agents; Cocaine; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Humans; Motor Activity; Rats; Schizophrenia; Stereotyped Behavior; Substance-Related Disorders | 1997 |
Effects of haloperidol and cocaine pretreatments on brain distribution and kinetics of [11C]methamphetamine in methamphetamine sensitized dog: application of PET to drug pharmacokinetic study.
Topics: Animals; Brain; Carbon Radioisotopes; Cocaine; Dogs; Haloperidol; Kinetics; Methamphetamine; Organ Specificity; Tissue Distribution; Tomography, Emission-Computed | 1997 |
Effect of the haloperidol tetrahydropyridine metabolite 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6- tetrahydropyridine on dopamine receptor and transporter binding. A nonhuman primate 123I-iodobenzamide and 2 beta-carbomethoxy-3 beta-(4-
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Haloperidol; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Pyrrolidines; Receptors, Dopamine; Tomography, Emission-Computed, Single-Photon | 1997 |
Mazindol and lidocaine are antinociceptives in the mouse formalin model: involvement of dopamine receptor.
Topics: Anesthetics, Local; Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; Lidocaine; Male; Mazindol; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Dopamine; Receptors, Opioid | 1997 |
Physiological and subjective effects of acute cocaine withdrawal (crash) in rats.
Topics: Animals; Body Temperature; Cocaine; Discrimination Learning; Electroencephalography; Haloperidol; Individuality; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors | 1997 |
The thymolytic effect of cocaine and monoaminergic drugs in the mouse.
Topics: Animals; Apomorphine; Biogenic Monoamines; Brain; Cocaine; DNA; Haloperidol; In Vitro Techniques; Male; Mice; Organ Size; Thymidine; Thymus Gland | 1998 |
Effects of dopaminergic drugs, occlusal disharmonies, and chronic stress on non-functional masticatory activity in the rat, assessed by incisal attrition.
Topics: Analysis of Variance; Animals; Apomorphine; Bruxism; Cocaine; Dental Occlusion, Traumatic; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Incisor; Male; Masticatory Muscles; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Stress, Physiological; Tooth Attrition | 1998 |
Modification of cataleptic responses to dopamine receptor antagonists after withdrawal from chronic cocaine or cocaine plus dopamine antagonist administration.
Topics: Animals; Antipsychotic Agents; Catalepsy; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome | 1998 |
Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cerebral Cortex; Cocaine; COS Cells; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Gene Expression; Genes, Immediate-Early; GTP Phosphohydrolases; GTP-Binding Proteins; Haloperidol; Hippocampus; Hydrolysis; Lipid Metabolism; Male; Neuronal Plasticity; Neurons; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Signal Transduction; Synaptic Transmission | 1998 |
Cocaine-induced activation of striatal neurons during focused stereotypy in rats.
Topics: Amphetamine; Animals; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electrophysiology; Haloperidol; Male; Neostriatum; Neurons; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1998 |
Psychotomimetic-induction of tissue plasminogen activator mRNA in corticostriatal neurons in rat brain.
Topics: Animals; Benzazepines; Central Nervous System Agents; Cocaine; Corpus Striatum; Dopamine Antagonists; Haloperidol; In Situ Hybridization; Male; Methamphetamine; Neurons; Nomifensine; Phencyclidine; Rats; Rats, Wistar; RNA Probes; RNA, Messenger; Tissue Plasminogen Activator | 1998 |
Microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cocaine; Corpus Striatum; Corticosterone; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Male; Microinjections; Prefrontal Cortex; Quinpirole; Rats; Rats, Sprague-Dawley | 1998 |
Discriminative stimulus effects of S(-)-methcathinone (CAT): a potent stimulant drug of abuse.
Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Fenfluramine; Haloperidol; Male; Propiophenones; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1998 |
Chronic haloperidol alters dopamine receptors: effects of cocaine exposure during the preweaning period.
Topics: Animals; Autoradiography; Basal Ganglia; Benzazepines; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Haloperidol; Male; Piperazines; Prosencephalon; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Sex Factors; Time Factors; Weaning | 1999 |
Although chemically related to amineptine, the antidepressant tianeptine is not a dopamine uptake inhibitor.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzazepines; Cocaine; Corpus Striatum; Dextroamphetamine; Dibenzocycloheptenes; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Haloperidol; In Vitro Techniques; Male; Mice; Motor Activity; Radioligand Assay; Thiazepines | 1999 |
Inability of antipsychotics to antagonize the cueing properties of cocaine in rats.
Topics: Animals; Antipsychotic Agents; Cocaine; Cues; Discrimination, Psychological; Dopamine Uptake Inhibitors; Generalization, Stimulus; Haloperidol; Male; Rats; Rats, Inbred Strains | 1999 |
S18327 (1-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)piperid-1-yl]ethyl]3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1)- and alpha(2)-adrenergic receptors: II. Functional profile and a multipara
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Antagonists; Aggression; Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Clozapine; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Extrapyramidal Tracts; Haloperidol; Imidazoles; Isoxazoles; Male; Mice; Pain Measurement; Protein Binding; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Muscarinic | 2000 |
cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; beta-Galactosidase; Brain Chemistry; Cocaine; Coloring Agents; Cyclic AMP Response Element-Binding Protein; Desipramine; Dopamine Uptake Inhibitors; Fluoxetine; Haloperidol; Lac Operon; Mice; Mice, Transgenic; Monoamine Oxidase Inhibitors; Phosphorylation; Transcription, Genetic; Tranylcypromine; Up-Regulation | 2000 |
8-OH DPAT can restore the locomotor stimulant effects of cocaine blocked by haloperidol.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Brain Chemistry; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Haloperidol; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Time Factors | 2000 |
Neurotensin gene expression and behavioral responses following administration of psychostimulants and antipsychotic drugs in dopamine D(3) receptor deficient mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Brain; Catalepsy; Cocaine; Dopamine Uptake Inhibitors; Female; Gene Expression; Haloperidol; Male; Mice; Mice, Mutant Strains; Motor Activity; Neurotensin; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger | 2001 |
Effects of pertussis toxin on behavioral responses during different withdrawal periods from chronic cocaine treatment.
Topics: Adenosine Diphosphate Ribose; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Catalepsy; Cocaine; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Pertussis Toxin; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Virulence Factors, Bordetella | 2000 |
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium | 2000 |
Effects of nitric oxide synthase inhibitors on the discriminative stimulus effects of cocaine in rats.
Topics: Animals; Benzazepines; Cocaine; Discrimination, Psychological; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Haloperidol; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2001 |
Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Sequence; Animals; Autoradiography; Brain; Cell Line; Cocaine; Conserved Sequence; Corpus Striatum; Dopamine; Dopamine Antagonists; Down-Regulation; Gene Expression Regulation; Haloperidol; In Situ Hybridization; Kruppel-Like Transcription Factors; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neuroblastoma; Neurons; Receptors, Dopamine; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factors; Transfection; Tumor Cells, Cultured; Zinc Fingers | 2001 |
Differential effects of dopamine antagonists on locomotor activity, conditioned activity and conditioned place preference induced by cocaine in rats.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2001 |
Neurobehavioral assessments of rats perinatally exposed to a commercial mixture of polychlorinated biphenyls.
Topics: Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal; Chlorodiphenyl (54% Chlorine); Cocaine; Cognition; Diet; Dose-Response Relationship, Drug; Female; Habituation, Psychophysiologic; Haloperidol; Lactation; Male; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Rats, Long-Evans; Stereotyped Behavior; Toxicity Tests; Visual Perception | 2002 |
Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats.
Topics: Animals; Behavior, Animal; Brain; Catalepsy; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Haloperidol; Male; Nitriles; Quinolines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Secondary Prevention; Self Administration; Spatial Behavior; Tetrahydroisoquinolines | 2002 |
Dopamine D3 receptor ligands show place conditioning effect but do not influence cocaine-induced place preference.
Topics: Animals; Avoidance Learning; Benzazepines; Benzopyrans; Cocaine; Conditioning, Classical; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Indans; Male; Naphthalenes; Nitriles; Oxazines; Piperazines; Pyrrolidines; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Spatial Behavior; Substance-Related Disorders; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2003 |
Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electrochemistry; Haloperidol; Male; Microdialysis; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT3 Receptor Antagonists; Tropanes | 2003 |
Selective tolerance to the hypothermic and anticataleptic effects of a neurotensin analog that crosses the blood-brain barrier.
Topics: Amphetamine; Animals; Behavior, Animal; Blood Glucose; Blood-Brain Barrier; Body Temperature; Brain; Catalepsy; Cocaine; Drug Tolerance; Haloperidol; Hyperkinesis; Hypothermia; Male; Neurotensin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110.
Topics: Animals; Antipsychotic Agents; Benzamides; Binding, Competitive; Body Temperature; Catalepsy; Cell Line; Clozapine; Cocaine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Humans; Hypothermia; Isoxazoles; Male; Mice; Motor Activity; Prolactin; Psychomotor Performance; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes; Thiophenes; Tritium | 2003 |
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum.
Topics: Aminopyridines; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Electrochemistry; Ethylamines; Extracellular Space; Haloperidol; Indoles; Male; Microdialysis; Nucleus Accumbens; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Time Factors | 2004 |
Combined effects of psychostimulants and morphine on locomotor activity in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Methamphetamine; Mice; Morphine; Motor Activity | 2004 |
Monoaminergic drugs and directly observable signs of LAAM withdrawal in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Biogenic Monoamines; Clonidine; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Methadyl Acetate; Muscle Rigidity; Naltrexone; Narcotic Antagonists; Respiratory Mechanics; Salivation; Substance Withdrawal Syndrome | 2005 |
Sex differences in neurochemical effects of dopaminergic drugs in rat striatum.
Topics: Analysis of Variance; Animals; Brain Chemistry; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Radiation; Electric Stimulation; Electrochemistry; Female; Haloperidol; Male; Quinpirole; Rats; Sex Characteristics; Synaptosomes; Time Factors | 2006 |
Effects of memantine, haloperidol, and cocaine on primary and conditioned reinforcement associated with cocaine in rhesus monkeys.
Topics: Animals; Cocaine; Conditioning, Classical; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Macaca mulatta; Male; Memantine; Reinforcement, Psychology | 2006 |
N-[2-(m-methoxyphenyl)ethyl]-N-ethyl-2-(1-pyrrolidinyl)ethylamine (UMB 116) is a novel antagonist for cocaine-induced effects.
Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Cocaine; Dose-Response Relationship, Drug; Ethylamines; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Pyrrolidines; Radioligand Assay; Receptors, sigma; Seizures; Survival Rate | 2006 |
Heterogeneous dopamine neurochemistry in the striatum: the fountain-drain matrix.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Electrochemistry; Haloperidol; Hydrogen-Ion Concentration; Male; Medial Forebrain Bundle; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2006 |
Effects of pregnanolone in rats discriminating cocaine.
Topics: Animals; Bupropion; Cocaine; Desipramine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Haloperidol; Male; Pregnanolone; Rats; Rats, Long-Evans; Receptors, GABA-A | 2006 |
Effects of two novel D3-selective compounds, NGB 2904 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide] and CJB 090 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(pyridin-2-yl)benzamide], on the reinforcing and discrimin
Topics: Animals; Cocaine; Conditioning, Psychological; Discrimination Learning; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluorenes; Haloperidol; Macaca mulatta; Male; Piperazines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Reinforcement, Psychology | 2007 |
Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M5 muscarinic acetylcholine receptor knockout mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cocaine; Dextroamphetamine; Dopamine Agonists; Female; Genotype; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Muscarinic Agonists; Receptors, Muscarinic; Reflex; Reflex, Startle; Schizophrenia; Trihexyphenidyl | 2007 |
Haloperidol (but not ziprasidone) withdrawal enhances cocaine-induced locomotor activation and conditioned place preference in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Motor Activity; Substance Withdrawal Syndrome | 2007 |
Heterogeneous population of dopaminergic neurons derived from mouse embryonic stem cells: preliminary phenotyping based on receptor expression and function.
Topics: Acetylcholine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Atropine; Calcium; Cell Differentiation; Cells, Cultured; Cholinergic Agents; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Embryonic Stem Cells; Fluorescent Dyes; Glutamic Acid; Haloperidol; Mice; Microtubule-Associated Proteins; Muscarinic Antagonists; Neurons; Norepinephrine; Phenotype; Tetrodotoxin; Tritium; Tyrosine 3-Monooxygenase | 2007 |
GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs.
Topics: Animals; Blotting, Western; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Haloperidol; Immunoprecipitation; Locomotion; Male; Mice; Mice, Knockout; Presynaptic Terminals; Receptors, G-Protein-Coupled | 2007 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Complicated interaction between psychostimulants and morphine in expression of phenotype of behavior in the dopaminergic system of BALB/c mice.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Limbic System; Male; Methamphetamine; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Neurons; Substantia Nigra; Time Factors | 2007 |
Differential antagonism of cocaine self-administration and cocaine-induced disruptions of learning by haloperidol in rhesus monkeys.
Topics: Animals; Antipsychotic Agents; Cocaine; Drug Administration Schedule; Haloperidol; Learning Disabilities; Macaca mulatta; Male; Self Administration | 2008 |
Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol.
Topics: Analysis of Variance; Animals; Cocaine; Corpus Striatum; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Gene Expression Regulation; Genes, Immediate-Early; Green Fluorescent Proteins; Haloperidol; Histones; Mice; Mice, Transgenic; Motor Activity; Neurons; Receptors, Dopamine D1; Receptors, Dopamine D2; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Time Factors | 2008 |
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Chromosomes, Artificial, Bacterial; Clozapine; Cocaine; Corpus Striatum; Dopamine and cAMP-Regulated Phosphoprotein 32; Globus Pallidus; Haloperidol; Mice; Mice, Transgenic; Neurons; Organ Culture Techniques; Phosphorylation; Substantia Nigra | 2008 |
Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Haloperidol; Humans; Male; Mice; Motor Activity; Piperazines; Schizophrenia; Substance Withdrawal Syndrome; Thiazoles | 2008 |
Examination of reinforcement magnitude on the pharmacological disruption of fixed-ratio performance.
Topics: Animals; Chlordiazepoxide; Clonidine; Cocaine; Columbidae; Conditioning, Operant; Ethanol; Extinction, Psychological; Food Deprivation; Haloperidol; Morphine; Reinforcement Schedule; Reinforcement, Psychology; Time Factors | 2009 |
Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum.
Topics: Animals; Behavior, Animal; beta-Cyclodextrins; Brain-Derived Neurotrophic Factor; Cholesterol; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dronabinol; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Agents; Haloperidol; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phenols; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward | 2010 |
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors.
Topics: Animals; Catalepsy; Cocaine; Corpus Striatum; Dopamine Agents; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Fluorescent Antibody Technique; Green Fluorescent Proteins; Haloperidol; Immunohistochemistry; Levodopa; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Motor Activity; Neuronal Plasticity; Neurons; Synaptic Potentials | 2010 |
Double dissociation of the effects of haloperidol and the dopamine D3 receptor antagonist ABT-127 on acquisition vs. expression of cocaine-conditioned activity in rats.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Cocaine; Conditioning, Psychological; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Motor Activity; Piperazines; Protein Binding; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Stereotyped Behavior | 2010 |
A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid.
Topics: Analysis of Variance; Animals; Appetitive Behavior; Baclofen; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Consummatory Behavior; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluoxetine; GABA-B Receptor Agonists; Haloperidol; Infusions, Intravenous; Male; Models, Theoretical; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Self Administration; Time Factors | 2011 |
Chronic cocaine administration reduces striatal dopamine terminal density and striatal dopamine release which leads to drug-seeking behaviour.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavior; Haloperidol; Male; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission | 2011 |
The effects of haloperidol on cocaine-induced conditioned taste aversions.
Topics: Analysis of Variance; Animals; Association Learning; Avoidance Learning; Cocaine; Conditioning, Classical; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Taste | 2012 |
Interactions between dopamine transporter and cannabinoid receptor ligands in rhesus monkeys.
Topics: Amphetamine; Animals; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Dronabinol; Female; Haloperidol; Imipramine; Macaca mulatta; Male; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Tropanes | 2012 |
A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Attention; Benzodiazepines; Body Weight; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Electroencephalography; Hallucinogens; Haloperidol; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Mental Recall; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microinjections; Motor Activity; Mutation; Olanzapine; Oocytes; Oxazoles; Phencyclidine; Phenethylamines; Protein Binding; Pyrrolidinones; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reinforcement, Psychology; Schizophrenia; Swimming; Telemetry; Tritium; Xenopus | 2013 |
Impulse-dependent extracellular resting dopamine concentration in rat striatum in vivo.
Topics: Algorithms; Animals; Cocaine; Computer Simulation; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Electric Stimulation; Electrochemistry; Extracellular Space; Haloperidol; Kinetics; Male; Medial Forebrain Bundle; Neostriatum; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2013 |
Selective action of an atypical neuroleptic on the mechanisms related to the development of cocaine addiction: a pre-clinical behavioural study.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Mice; Motor Activity; Piperazines; Quinolones; Thiazoles | 2014 |
Pavlovian discriminative stimulus effects of methamphetamine in male Japanese quail (Coturnix japonica).
Topics: Animals; Benzazepines; Central Nervous System Stimulants; Cocaine; Conditioning, Classical; Coturnix; Discrimination, Psychological; Female; Generalization, Psychological; Haloperidol; Male; Methamphetamine; Nicotine; Receptors, Dopamine D1; Sexual Behavior, Animal | 2014 |
Central serotonin(2B) receptor blockade inhibits cocaine-induced hyperlocomotion independently of changes of subcortical dopamine outflow.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Male; Motor Activity; Pyrimidines; Quinpirole; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Serotonin 5-HT2 Receptor Antagonists | 2015 |
Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions.
Topics: Amphetamine; Animals; Behavior, Animal; beta-Arrestins; Cocaine; Dopamine; Female; Genetic Vectors; Haloperidol; Heterotrimeric GTP-Binding Proteins; Male; Mice; Mice, Knockout; Mice, Transgenic; Phencyclidine; Receptors, Dopamine D2; Signal Transduction | 2018 |
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists | 2020 |