cocaine and gbr 12935

cocaine has been researched along with gbr 12935 in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.36)	18.7374
1990's	36 (64.29)	18.2507
2000's	15 (26.79)	29.6817
2010's	2 (3.57)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
de Costa, BR; Dersch, CM; Glowa, JR; Matecka, D; Partilla, JS; Pert, A; Radesca, L; Rice, KC; Rothman, RB; Wojnicki, FH	1
Choi, SW; Elmaleh, DR; Fischman, AJ; Hanson, RN	1
Chang, LT; Dersch, CM; Hsin, LW; Jacobson, AE; Rice, KC; Rothman, RB	1
Farfel, GM; Kleven, MS; Perry, BD; Seiden, LS; Woolverton, WL	1
de Costa, B; Jacobson, AE; Reith, ME; Rice, KC	1
Reith, ME; Wiener, HL	1
Boja, JW; Carroll, FI; Gao, Y; Kuhar, MJ; Lever, J; Lew, R; Lewin, AH; Patel, A; Philip, A; Simantov, R	1
Reith, ME; Selmeci, G	1
Arroyo, J; Berger, P; Elsworth, JD; Roth, RH	1
Allard, P; Eriksson, K; Marcusson, JO; Ross, SB	1
Cox, BM; Izenwasser, S; Jacocks, HM; Rosenberger, JG	1
Bradberry, CW; Elsworth, JD; Jatlow, P; Roth, RH; Russell, R; Taylor, JR; Winger, G	1
Baldessarini, RJ; Kula, NS	1
Ho, IK; Hoskins, B; Lim, DK; Rockhold, RW; Yu, ZJ	1
Berger, P; Elsworth, JD; Reith, ME; Roth, RH; Tanen, D	1
Johnson, KM; Yi, SJ	1
Akunne, H; Greig, N; Mele, A; Pert, A; Reid, AA; Rice, KC; Rothman, RB; Thurkauf, A	1
Cox, BM; Izenwasser, S; Werling, LL	1
Eriksson, K; Marcusson, J	1
Eshleman, AJ; Janowsky, A; Neve, KA; Neve, RL	1
Coen, KM; Corrigall, WA; Kish, SJ; Nobrega, JN; Shannak, K; Wilson, JM	1
Abraham, P; Boja, JW; Cadet, JL; Carroll, FI; Kopajtic, TA; Lever, J; Lewin, AH; Seltzman, HH; Wyrick, CD	1
Chen, NH; Reith, ME	1
Carney, JM; Tolliver, BK	1
Casanova, MF; Hitri, A; Kleinman, JE; Wyatt, RJ	1
Akunne, HC; Baumann, MH; Cadet, JL; Carroll, FI; de Costa, BR; Partilla, JS; Rice, KC; Rothman, RB; Silverthorn, ML; Wang, JB	1
Carroll, ME; Dixon, LM; Kish, SJ; Lac, ST; Niznik, HB; Nobrega, JN; Pristupa, ZB; Shannak, K; Wilson, JM	1
Hoffman, BJ; Kish, SJ; Niznik, HB; Pristupa, ZB; Wilson, JM	1
Becketts, KM; Carroll, FI; de Costa, BR; Dersch, CM; Radesca, LR; Rice, KC; Rothman, RB	1
Richfield, EK	1
Acri, JB; Siedleck, BK; Witkin, JM	1
Darmani, NA	2
Collins, LM; Meyer, JS	1
Ellinwood, EH; Hitri, A; Little, KY	1
Darmani, NA; Reeves, SL	1
Descarries, L; Doucet, G; Lafaille, F; Mrini, A; Soucy, JP	1
Dersch, CM; DeVries, AC; Glowa, JR; Lewis, D; Matecka, D; Pert, A; Rice, KC; Rothman, RB; Wojnicki, FH	1
Hitri, A; Wyatt, RJ	1
Bonnet, JJ; Corera, AT; Do Régo, JC	1
Baldessarini, RJ; Fisser, R; Kula, NS; Neumeyer, JL; Tarazi, FI; Trometer, J; Wang, S	1
Carroll, FI; Kimmel, HL; Kuhar, MJ	2
Dohi, T; Ikeda, T; Kitayama, S; Morita, K; Sato, T	1
Beard, JL; Erikson, KM; Jones, BC	1
Goldberg, SR; Tella, SR	1
Beardsley, PM; Cook, CD; Davis, MC; Dutta, AK; Fei, XS; Reith, ME	1
Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K	1
Chan, PM; Emson, PC; Mooslehner, KA; Patel, J; Stamford, JA	1
Berfield, JL; Chen, N; Reith, ME; Rickey, J	1
Chen, N; Dutta, AK; Maiti, S; Reith, ME; Zhen, J	1
Swant, J; Thompson, AM; Wagner, JJ	1
Arnfred, S; Bender, D; Cumming, P; Danielsen, EH; Grant, R; Minuzzi, L; Olsen, AK	1
Booze, RM; Mactutus, CF; Wallace, DR; Zhu, J	1
Chen, L; Wang, L; Ye, JH; Zuo, W	1
Chen, YH; Good, CH; Hoffman, AF; Lupica, CR; Mejias-Aponte, CA; Wang, H	1

Other Studies

56 other study(ies) available for cocaine and gbr 12935

Article	Year
Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909). Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24 Topics: Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Conformation; Molecular Structure; Nerve Tissue Proteins; Piperazines; Rats; Receptors, Drug; Serotonin; Substance-Related Disorders	1996
Novel 3-aminomethyl- and 4-aminopiperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazines: synthesis and evaluation as dopamine transporter ligands. Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2 Topics: Carrier Proteins; Cell Line; Dopamine Plasma Membrane Transport Proteins; Humans; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperazines	2000
Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: role of amino, fluoro, hydroxyl, methoxyl, methyl, m Journal of medicinal chemistry, 2008, May-08, Volume: 51, Issue:9 Topics: Dopamine Plasma Membrane Transport Proteins; Piperazines; Radioligand Assay; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship	2008
Effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey. Brain research, 1992, Apr-24, Volume: 578, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benzazepines; Brain; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Grooming; Homovanillic Acid; Hydroxyindoleacetic Acid; Iodocyanopindolol; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Organ Specificity; Pindolol; Piperazines; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin; Spiperone; Stereotyped Behavior; Time Factors	1992
Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter. European journal of pharmacology, 1992, Dec-01, Volume: 227, Issue:4 Topics: Animals; Binding Sites; Binding, Competitive; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley	1992
Determination of radioligand specific activity using competition binding assays. Analytical biochemistry, 1992, Nov-15, Volume: 207, Issue:1 Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Female; Kinetics; Ligands; Male; Mice; Mice, Inbred C57BL; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tritium	1992
A cocaine analog and a GBR analog label the same protein in rat striatal membranes. Brain research, 1992, Mar-27, Volume: 576, Issue:1 Topics: Animals; Azides; Binding Sites; Carrier Proteins; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electrophoresis, Polyacrylamide Gel; Iodine Radioisotopes; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats	1992
Radiolabeling of dopamine uptake sites in mouse striatum: comparison of binding sites for cocaine, mazindol, and GBR 12935. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:3 Topics: Animals; Binding Sites; Buffers; Cocaine; Corpus Striatum; Dopamine; Drug Interactions; Ethylmaleimide; Kinetics; Male; Mazindol; Membranes; Mice; Mice, Inbred BALB C; Phosphates; Piperazines; Radioligand Assay; Temperature; Tritium; Tromethamine	1992
Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens. European journal of pharmacology, 1990, Feb-20, Volume: 177, Issue:1-2 Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains; Septal Nuclei	1990
Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs. Psychopharmacology, 1990, Volume: 102, Issue:3 Topics: Animals; Binding, Competitive; Bromocriptine; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Haloperidol; Kinetics; Male; Piperazines; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Salicylamides	1990
Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. Journal of neurochemistry, 1991, Volume: 56, Issue:2 Topics: Animals; Binding, Competitive; Carbachol; Chlorisondamine; Cocaine; Corpus Striatum; Dimethylphenylpiperazinium Iodide; Dopamine; Dose-Response Relationship, Drug; Male; Mecamylamine; Nicotine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Synaptosomes	1991
Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life sciences, 1991, Volume: 48, Issue:18 Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Macaca mulatta; Motor Activity; Nucleus Accumbens; Piperazines; Rats; Receptors, Dopamine; Self Administration; Synaptosomes	1991
Lack of increase in dopamine transporter binding or function in rat brain tissue after treatment with blockers of neuronal uptake of dopamine. Neuropharmacology, 1991, Volume: 30, Issue:1 Topics: Animals; Benztropine; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Reference Values	1991
Effects of acute and subacute cocaine administration on the CNS dopaminergic system in Wistar-Kyoto and spontaneously hypertensive rats: III. Dopamine uptake. Neurochemical research, 1990, Volume: 15, Issue:6 Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Hypertension; Kinetics; Male; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1990
Complex interaction of cocaine with the dopamine uptake carrier. European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2 Topics: Animals; Cocaine; Corpus Striatum; Desipramine; In Vitro Techniques; Kinetics; Male; Mazindol; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Vas Deferens	1990
Effects of acute and chronic administration of cocaine on striatal uptake, compartmentalization and release of [3H]dopamine. Neuropharmacology, 1990, Volume: 29, Issue:5 Topics: Acetylcholine; Amphetamine; Amygdala; Animals; Cocaine; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Kinetics; Nucleus Accumbens; Piperazines; Potassium; Rats; Synaptosomes	1990
Tight binding dopamine reuptake inhibitors as cocaine antagonists. A strategy for drug development. FEBS letters, 1989, Nov-06, Volume: 257, Issue:2 Topics: Animals; Biological Transport; Carrier Proteins; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Extracellular Space; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Inbred Strains	1989
Binding of [3H]GBR 12935 in the striatum, medial prefrontal cortex, nucleus accumbens and olfactory tubercle of rat. NIDA research monograph, 1989, Volume: 95 Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Frontal Lobe; Nucleus Accumbens; Olfactory Bulb; Piperazines; Psychotropic Drugs; Rats; Receptors, Dopamine; Septal Nuclei	1989
[3H]GBR-12935 binding to dopamine uptake sites in the human brain. Brain research, 1988, Aug-02, Volume: 457, Issue:1 Topics: Aged; Aged, 80 and over; Binding, Competitive; Brain; Cocaine; Dopamine; Female; Humans; Male; Mazindol; Middle Aged; Piperazines; Receptors, Dopamine	1988
Characterization of a recombinant human dopamine transporter in multiple cell lines. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Recombinant Proteins; Tritium; Tumor Cells, Cultured	1995
Amygdala dopamine levels are markedly elevated after self- but not passive-administration of cocaine. Brain research, 1994, Dec-30, Volume: 668, Issue:1-2 Topics: Amygdala; Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Self Stimulation; Serotonin	1994
Selective labeling of the dopamine transporter by the high affinity ligand 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester. Molecular pharmacology, 1995, Volume: 47, Issue:4 Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley	1995
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships. Journal of neurochemistry, 1994, Volume: 63, Issue:5 Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area	1994
Comparison of cocaine and GBR 12935: effects on locomotor activity and stereotypy in two inbred mouse strains. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:3 Topics: Animals; Cocaine; Drug Tolerance; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Piperazines; Species Specificity; Stereotyped Behavior	1994
Fewer dopamine transporter receptors in the prefrontal cortex of cocaine users. The American journal of psychiatry, 1994, Volume: 151, Issue:7 Topics: Adult; Aged; Cocaine; Down-Regulation; Female; Frontal Lobe; Humans; Ligands; Male; Middle Aged; Piperazines; Receptors, Dopamine; Substance-Related Disorders	1994
Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin Plasma Membrane Transport Proteins	1994
Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:5 Pt 2 Topics: Animals; Biogenic Monoamines; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Wistar; Reference Values; Self Administration; Substance Withdrawal Syndrome; Time Factors; Tissue Distribution; Tritium	1994
Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding. Molecular pharmacology, 1994, Volume: 45, Issue:1 Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cells, Cultured; Cloning, Molecular; Cocaine; DNA; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Piperazines	1994
Studies of the biogenic amine transporters. II. A brief study on the use of [3H]DA-uptake-inhibition to transporter-binding-inhibition ratios for the in vitro evaluation of putative cocaine antagonists. Life sciences, 1993, Volume: 53, Issue:17 Topics: Animals; Biogenic Amines; Biological Transport; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Tritium	1993
Zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex. Molecular pharmacology, 1993, Volume: 43, Issue:1 Topics: Animals; Binding, Competitive; Buffers; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ethylmaleimide; In Vitro Techniques; Male; Membrane Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Zinc	1993
Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1 Topics: Animals; Atropine; Behavior, Animal; Benztropine; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Male; Mice; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Seizures	1996
Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline. Life sciences, 1996, Volume: 59, Issue:14 Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan	1996
Prenatal cocaine alters dopamine transporter binding in postnatal day 10 rat striatum. Synapse (New York, N.Y.), 1996, Volume: 23, Issue:4 Topics: Animals; Autoradiography; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Drug Implants; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Piperazines; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley	1996
Effect of cocaine on dopamine transporter receptors depends on routes of chronic cocaine administration. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 14, Issue:3 Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Drug Administration Routes; Frontal Lobe; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine	1996
The stimulatory and inhibitory components of cocaine's actions on the 5-HTP-induced 5-HT2A receptor response. Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:3 Topics: 1-Naphthylamine; 5-Hydroxytryptophan; Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline	1996
Comparative evaluation of [3H]WIN 35428 and [3H]GBR 12935 as markers of dopamine innervation density in brain. Synapse (New York, N.Y.), 1997, Volume: 25, Issue:2 Topics: Animals; Autoradiography; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Piperazines; Rats; Rats, Sprague-Dawley	1997
Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors. Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5 Topics: Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Feeding Behavior; Ligands; Macaca mulatta; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Nerve Tissue Proteins; Pentazocine; Piperazines; Rats; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship	1997
Regional differences in rat brain dopamine transporter binding: function of time after chronic cocaine. Clinical neuropharmacology, 1993, Volume: 16, Issue:6 Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Narcotics; Neostriatum; Nerve Tissue Proteins; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	1993
Cocaine and selective monoamine uptake blockers (sertraline, nisoxetine, and GBR 12935) prevent the d-fenfluramine-induced head-twitch response in mice. Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1 Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Fenfluramine; Fluoxetine; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline	1998
Specificity and ion dependence of binding of GBR analogs. Methods in enzymology, 1998, Volume: 296 Topics: Animals; Carrier Proteins; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tritium	1998
[3H]beta-CIT: a radioligand for dopamine transporters in rat brain tissue. European journal of pharmacology, 1999, Dec-03, Volume: 385, Issue:2-3 Topics: Amphetamine; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Tritium	1999
Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76. Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4 Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Injections, Intraventricular; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Symporters; Tropanes	2000
Changes in seizure susceptibility to local anesthetics by repeated administration of cocaine and nomifensine but not GBR12935: possible involvement of noradrenergic system. Japanese journal of pharmacology, 2000, Volume: 83, Issue:3 Topics: Anesthetics, Local; Animals; Cocaine; Male; Mice; Mice, Inbred ICR; Nomifensine; Norepinephrine; Piperazines; Seizures	2000
Iron deficiency alters dopamine transporter functioning in rat striatum. The Journal of nutrition, 2000, Volume: 130, Issue:11 Topics: Analysis of Variance; Anemia, Iron-Deficiency; Animals; Carrier Proteins; Cocaine; Corpus Striatum; Diet; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Liver; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Piperazines; Potassium Chloride; Rats; Rats, Sprague-Dawley	2000
Subtle differences in the discriminative stimulus effects of cocaine and GBR-12909. Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:3 Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors	2001
Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules. Journal of medicinal chemistry, 2002, Jan-31, Volume: 45, Issue:3 Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Discrimination Learning; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Piperidines; Radioligand Assay; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters	2002
Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1 Topics: Animals; Behavior, Animal; Cocaine; Dopamine Plasma Membrane Transport Proteins; Half-Life; In Vitro Techniques; Injections, Intraventricular; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Motor Activity; Neostriatum; Nerve Tissue Proteins; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tropanes	2003
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics. Brain research, 2003, Feb-21, Volume: 964, Issue:1 Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lidocaine; Male; Maprotiline; Mice; Mice, Inbred ICR; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Seizures; Selective Serotonin Reuptake Inhibitors; Symporters; Time Factors	2003
Presynaptic control of striatal dopamine neurotransmission in adult vesicular monoamine transporter 2 (VMAT2) mutant mice. Journal of neurochemistry, 2003, Volume: 85, Issue:4 Topics: Amphetamine; Animals; Autoreceptors; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; Electrochemistry; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mice; Mice, Neurologic Mutants; Nalidixic Acid; Naphthyridines; Nerve Tissue Proteins; Neurons; Neuropeptides; Piperazines; Presynaptic Terminals; Synaptic Transmission; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins	2003
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding. The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7 Topics: Alanine; Aspartic Acid; Biological Transport; Biotinylation; Blotting, Western; Cell Line; Cell Membrane; Cocaine; Cystine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Mutation; Nerve Tissue Proteins; Phenotype; Piperazines; Protein Binding; Protein Conformation; Protein Transport; Sodium; Time Factors; Zinc	2004
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter. European journal of pharmacology, 2004, Dec-03, Volume: 506, Issue:1 Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Biological Transport; Cell Line; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nerve Tissue Proteins; Norepinephrine; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism; Synaptosomes; Tritium	2004
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus. Neuropharmacology, 2005, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Benzazepines; Cocaine; Desipramine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Neurotransmitter Uptake Inhibitors; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrodotoxin	2005
Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo. Synapse (New York, N.Y.), 2006, Mar-15, Volume: 59, Issue:4 Topics: Age Factors; Animals; Autoradiography; Binding, Competitive; Brain; Cocaine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Ferrets; Humans; In Vitro Techniques; Ligands; Piperazines; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Rats; Receptors, Dopamine; Swine; Swine, Miniature	2006
HIV-1 Tat protein-induced rapid and reversible decrease in [3H]dopamine uptake: dissociation of [3H]dopamine uptake and [3H]2beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane (WIN 35,428) binding in rat striatal synaptosomes. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3 Topics: Animals; Binding Sites; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Leucine; Male; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Surface Plasmon Resonance; Synaptosomes; tat Gene Products, Human Immunodeficiency Virus	2009
Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons. Neuropharmacology, 2013, Volume: 70 Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium Channels; Cocaine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABAergic Neurons; Glutamic Acid; Habenula; Male; Miniature Postsynaptic Potentials; Piperazines; Quinoxalines; Quinpirole; Raclopride; Rats; Receptors, Dopamine; Receptors, Glutamate; Sodium Channels; Synaptic Transmission	2013
Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Oct-23, Volume: 33, Issue:43 Topics: Action Potentials; Amphetamine; Animals; Cesium; Cocaine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Feedback, Physiological; gamma-Aminobutyric Acid; Glutamic Acid; Habenula; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Neurons; Pedunculopontine Tegmental Nucleus; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D4; Synaptic Transmission; Ventral Tegmental Area	2013