cocaine and flupenthixol

cocaine has been researched along with flupenthixol in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.00)18.7374
1990's12 (30.00)18.2507
2000's8 (20.00)29.6817
2010's14 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuder, H; Muscholl, E1
Cole, JO; Gruber, AJ1
Spealman, RD1
Mackey, WB; van der Kooy, D1
Allen, D; Gawin, FH; Humblestone, B1
Boselli, C; Chiari, MC; Grana, E; Lucchelli, A1
Ennis, C; Gaskin, M; Robbins, TW; Watson, BA1
Bloom, FE; Ettenberg, A; Koob, GF; Pettit, HO1
Ellinwood, EH; Joyner, C; King, GR1
Richardson, NR; Roberts, DC; Smith, AM1
Gawin, FH; Jatlow, P; Khalsa-Denison, ME1
Lamas, X; Mello, NK; Nader, MA; Negus, SS1
Lamas, X; Mello, NK; Mendelson, JH; Negus, SS1
Wilkins, JN1
Gatch, MB; Mello, NK; Negus, SS1
Gatch, MB; Lamas, X; Mello, NK; Negus, SS1
Baldo, BA; Koob, GF; Markou, A1
Mello, NK; Negus, SS1
Bigelow, GE; Evans, SM; Fischman, MW; Foltin, RW; Levin, FR; Walsh, SL1
Negus, SS1
Barber, DJ; Desai, RI; Terry, P1
Ahmed, SH; Koob, GF1
Di Ciano, P; Everitt, BJ1
Platt, DM; Rowlett, JK; Spealman, RD1
Belin, D; Everitt, BJ1
Di Ciano, P1
Boleij, H; Broekhoven, MH; Cousijn, J; Guitart Masip, M; Snoeren, EM; Spooren, W; Vanderschuren, LJ; Veeneman, MM1
Broekhoven, MH; Damsteegt, R; Vanderschuren, LJ; Veeneman, MM1
Broekhoven, MH; Limpens, JH; van Ast, M; Vanderschuren, LJ; Veeneman, MM1
Cheng, K; Morrissey, E; Negus, SS; O'Connell, R; Rice, KC1
Belin, D; Everitt, BJ; Murray, JE1
Dominguez, HM; Ettenberg, A; Shelton, K; Su, ZI; von Furstenberg, VA; Wenzel, JM1
Achterberg, EJ; Schoffelmeer, AN; Schrama, L; Siviy, SM; Trezza, V; Vanderschuren, LJ1
Belin, D; Dalley, JW; Dilleen, R; Economidou, D; Everitt, BJ; Murray, JE; Pelloux, Y1
Aurbach, EL; O'Donnell, EG; Robinson, TE; Saunders, BT1
Damsteegt, R; Vanderschuren, LJ; Veeneman, MM1
Aalderink, M; Achterberg, EJ; Driel, NV; Houwing, DJ; Servadio, M; Trezza, V; van Kerkhof, LW; van Swieten, MM; Vanderschuren, LJ1
Bogyo, K; Ettenberg, A; Schick, T; Shelton, K1
Baars, AM; Hesseling, P; Lesscher, HM; Lozeman-van 't Klooster, JG; Spoelder, M; Styles, M; Vanderschuren, LJ1
Hearing, MC; Huffington, ED; Ingebretson, AE; Thomas, MJ1

Reviews

1 review(s) available for cocaine and flupenthixol

ArticleYear
Antidepressant effects of flupenthixol.
    Pharmacotherapy, 1991, Volume: 11, Issue:6

    Topics: Affect; Antidepressive Agents; Cocaine; Depressive Disorder; Flupenthixol; Humans; Schizophrenia; Substance-Related Disorders

1991

Trials

2 trial(s) available for cocaine and flupenthixol

ArticleYear
Antidepressant effects of flupenthixol.
    Pharmacotherapy, 1991, Volume: 11, Issue:6

    Topics: Affect; Antidepressive Agents; Cocaine; Depressive Disorder; Flupenthixol; Humans; Schizophrenia; Substance-Related Disorders

1991
Effect of flupenthixol on subjective and cardiovascular responses to intravenous cocaine in humans.
    Drug and alcohol dependence, 2001, Nov-01, Volume: 64, Issue:3

    Topics: Adult; Analysis of Variance; Behavior, Addictive; Blood Pressure; Cardiovascular System; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Flupenthixol; Heart Rate; Humans; Injections, Intravenous; Male

2001

Other Studies

38 other study(ies) available for cocaine and flupenthixol

ArticleYear
The effect of dopamine on the overflow of endogenous noradrenaline from the perfused rabbit heart evoked by sympathetic nerve stimulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 305, Issue:2

    Topics: Animals; Cocaine; Dopamine; Dopamine Antagonists; Electric Stimulation; Female; Flupenthixol; Heart; In Vitro Techniques; Male; Myocardium; Norepinephrine; Rabbits; Sympathetic Nervous System

1978
Antagonism of behavioral effects of cocaine by selective dopamine receptor blockers.
    Psychopharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Benzazepines; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Flupenthixol; Male; Receptors, Dopamine; Reinforcement Schedule; Saimiri

1990
Neuroleptics block the positive reinforcing effects of amphetamine but not of morphine as measured by place conditioning.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Cocaine; Conditioning, Operant; Drug Interactions; Flupenthixol; Male; Morphine; Orientation; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Reward

1985
Outpatient treatment of 'crack' cocaine smoking with flupenthixol decanoate. A preliminary report.
    Archives of general psychiatry, 1989, Volume: 46, Issue:4

    Topics: Adult; Ambulatory Care; Cocaine; Female; Flupenthixol; Humans; Male; Substance-Related Disorders; Thioxanthenes

1989
Analysis of the relaxing effect of dopamine on the isolated rat jejunum.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:2

    Topics: Animals; Cocaine; Dopamine; Flupenthixol; Haloperidol; In Vitro Techniques; Jejunum; Male; Methacholine Compounds; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Tyramine

1986
Contrasting interactions of pipradrol, d-amphetamine, cocaine, cocaine analogues, apomorphine and other drugs with conditioned reinforcement.
    Psychopharmacology, 1983, Volume: 80, Issue:2

    Topics: Animals; Apomorphine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Flupenthixol; Male; Morphine; Piperidines; Rats; Reinforcement, Psychology

1983
Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems.
    Psychopharmacology, 1982, Volume: 78, Issue:3

    Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Flupenthixol; Heroin; Infusions, Parenteral; Male; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Self Administration

1982
Continuous or intermittent cocaine administration: effects of flupenthixol treatment during withdrawal.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Drug Tolerance; Flupenthixol; Infusion Pumps, Implantable; Male; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome

1994
A single injection of either flupenthixol decanoate or haloperidol decanoate produces long-term changes in cocaine self-administration in rats.
    Drug and alcohol dependence, 1994, Volume: 36, Issue:1

    Topics: Animals; Cocaine; Flupenthixol; Haloperidol; Injections, Intramuscular; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Substance-Related Disorders; Tranquilizing Agents

1994
Flupentixol-induced aversion to crack cocaine.
    The New England journal of medicine, 1996, May-16, Volume: 334, Issue:20

    Topics: Adult; Akathisia, Drug-Induced; Crack Cocaine; Flupenthixol; Humans; Male; Middle Aged; Substance-Related Disorders

1996
Effects of the putative dopamine D3 receptor agonist 7-OH-DPAT in rhesus monkeys trained to discriminate cocaine from saline.
    Psychopharmacology, 1996, Volume: 124, Issue:4

    Topics: Animals; Cocaine; Discrimination Learning; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Macaca mulatta; Male; Tetrahydronaphthalenes

1996
Acute and chronic effects of flupenthixol on the discriminative stimulus and reinforcing effects of cocaine in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:2

    Topics: Animals; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Eating; Flupenthixol; Macaca mulatta; Male

1996
Pharmacotherapy of schizophrenia patients with comorbid substance abuse.
    Schizophrenia bulletin, 1997, Volume: 23, Issue:2

    Topics: Alcoholism; Antipsychotic Agents; Cocaine; Flupenthixol; Humans; Imipramine; Marijuana Abuse; Opioid-Related Disorders; Schizophrenia; Self Medication; Substance-Related Disorders; Tobacco Use Disorder

1997
Discriminative stimulus effects of a cocaine/heroin "speedball" combination in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Azocines; Behavior, Animal; Cocaine; Discrimination Learning; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Combinations; Flupenthixol; Heroin; Macaca mulatta; Male; Narcotic Antagonists; Receptors, Opioid, mu

1998
Effects of heroin/cocaine combinations in rats trained to discriminate heroin or cocaine from saline.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:2

    Topics: Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Flupenthixol; Heroin; Male; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley

1998
Increased sensitivity to the locomotor depressant effect of a dopamine receptor antagonist during cocaine withdrawal in the rat.
    Psychopharmacology, 1999, Volume: 141, Issue:2

    Topics: Analysis of Variance; Animals; Cocaine; Dopamine Antagonists; Flupenthixol; Male; Motor Activity; Rats; Rats, Wistar; Self Administration; Substance Withdrawal Syndrome; Time Factors

1999
Effects of flupenthixol and quadazocine on self-administration of speedball combinations of cocaine and heroin by rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:4

    Topics: Animals; Azocines; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eating; Female; Flupenthixol; Heroin; Heroin Dependence; Macaca mulatta; Male; Narcotic Antagonists; Narcotics; Self Administration

1999
Rapid assessment of choice between cocaine and food in rhesus monkeys: effects of environmental manipulations and treatment with d-amphetamine and flupenthixol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:5

    Topics: Animals; Choice Behavior; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; Eating; Environment; Flupenthixol; Macaca mulatta; Male; Reaction Time

2003
Dopaminergic and cholinergic involvement in the discriminative stimulus effects of nicotine and cocaine in rats.
    Psychopharmacology, 2003, Volume: 167, Issue:4

    Topics: Acetylcholine; Animals; Cholinergic Agonists; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Flupenthixol; Generalization, Stimulus; Male; Mecamylamine; Muscarinic Agonists; Nicotine; Nicotinic Antagonists; Pilocarpine; Rats; Rats, Sprague-Dawley

2003
Changes in response to a dopamine receptor antagonist in rats with escalating cocaine intake.
    Psychopharmacology, 2004, Volume: 172, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Injections, Subcutaneous; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Self Administration

2004
Direct interactions between the basolateral amygdala and nucleus accumbens core underlie cocaine-seeking behavior by rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Aug-11, Volume: 24, Issue:32

    Topics: Amygdala; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine D2 Receptor Antagonists; Flupenthixol; Isoquinolines; Male; Microinjections; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, Kainic Acid; Self Administration; Tetrazoles

2004
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Extinction, Psychological; Fluoxetine; Flupenthixol; Grooming; Hydrocortisone; Injections, Intravenous; Norepinephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-2; Saimiri; Saliva; Self Administration; Thiophenes

2007
Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum.
    Neuron, 2008, Feb-07, Volume: 57, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Flupenthixol; Male; Nerve Net; Rats; Self Administration

2008
Distinct contributions of dopamine receptors in the nucleus accumbens core or shell to established cocaine reinforcement under a second-order schedule.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:12

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Flupenthixol; Male; Nucleus Accumbens; Rats; Receptors, Dopamine; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2008
Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine.
    Psychopharmacology, 2011, Volume: 214, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Male; Morphine; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reward; Thiazoles

2011
Distinct contributions of dopamine in the dorsolateral striatum and nucleus accumbens shell to the reinforcing properties of cocaine.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:2

    Topics: Animals; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Flupenthixol; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2012
Seeking-taking chain schedules of cocaine and sucrose self-administration: effects of reward size, reward omission, and α-flupenthixol.
    Psychopharmacology, 2012, Volume: 220, Issue:4

    Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Flupenthixol; Male; Rats; Rats, Wistar; Reinforcement Schedule; Reward; Self Administration; Sucrose

2012
Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:3

    Topics: Animals; Behavior, Animal; Cocaine; Diterpenes, Clerodane; Flupenthixol; Ketoprofen; Male; Oligopeptides; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Stimulation

2012
Double dissociation of the dorsomedial and dorsolateral striatal control over the acquisition and performance of cocaine seeking.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:11

    Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Male; Rats; Reinforcement Schedule; Reinforcement, Psychology; Self Administration

2012
The dopamine antagonist cis-flupenthixol blocks the expression of the conditioned positive but not the negative effects of cocaine in rats.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 114-115

    Topics: Animals; Cocaine; Dopamine Antagonists; Flupenthixol; Locomotion; Male; Motivation; Rats; Rats, Sprague-Dawley

2013
Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms.
    Psychopharmacology, 2014, Volume: 231, Issue:8

    Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Atomoxetine Hydrochloride; Behavior, Animal; Cocaine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Flupenthixol; Idazoxan; Male; Motor Activity; Piperazines; Play and Playthings; Propylamines; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Behavior

2014
Increased impulsivity retards the transition to dorsolateral striatal dopamine control of cocaine seeking.
    Biological psychiatry, 2014, Jul-01, Volume: 76, Issue:1

    Topics: Animals; Choice Behavior; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Flupenthixol; Impulsive Behavior; Male; Microinjections; Rats; Reinforcement, Psychology; Self Administration

2014
A cocaine context renews drug seeking preferentially in a subset of individuals.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:12

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Cues; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Flupenthixol; Individuality; Male; Motivation; Motor Activity; Nucleus Accumbens; Rats, Sprague-Dawley; Self Administration; Spatial Behavior

2014
The nucleus accumbens shell and the dorsolateral striatum mediate the reinforcing effects of cocaine through a serial connection.
    Behavioural pharmacology, 2015, Volume: 26, Issue:1-2

    Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Flupenthixol; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology

2015
Contrasting Roles of Dopamine and Noradrenaline in the Motivational Properties of Social Play Behavior in Rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Atomoxetine Hydrochloride; Cocaine; Conditioning, Operant; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Idazoxan; Male; Methylphenidate; Motivation; Neuropsychological Tests; Norepinephrine; Piperazines; Random Allocation; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Dopamine; Social Behavior

2016
Pharmacological modulation of lateral habenular dopamine D2 receptors alters the anxiogenic response to cocaine in a runway model of drug self-administration.
    Behavioural brain research, 2016, 09-01, Volume: 310

    Topics: Animals; Anxiety; Benzimidazoles; Catheters, Indwelling; Cocaine; Cocaine-Related Disorders; Conflict, Psychological; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Flupenthixol; Habenula; Male; Motor Activity; Rats, Sprague-Dawley; Receptors, Dopamine D2; Self Administration

2016
Dopaminergic neurotransmission in ventral and dorsal striatum differentially modulates alcohol reinforcement.
    The European journal of neuroscience, 2017, Volume: 45, Issue:1

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Corpus Striatum; Dopamine Antagonists; Flupenthixol; Male; Nucleus Accumbens; Rats; Reinforcement, Psychology; Synaptic Transmission

2017
Endogenous dopamine and endocannabinoid signaling mediate cocaine-induced reversal of AMPAR synaptic potentiation in the nucleus accumbens shell.
    Neuropharmacology, 2018, 03-15, Volume: 131

    Topics: Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Antagonists; Cocaine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Endocannabinoids; Flupenthixol; Long-Term Synaptic Depression; Male; Mice; Morpholines; Naphthalenes; Nucleus Accumbens; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rimonabant; Synaptic Transmission

2018