cocaine and ecopipam

cocaine has been researched along with ecopipam in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (56.25)18.2507
2000's7 (43.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergman, J; Rosenzweig-Lipson, S1
Spealman, RD1
Halldin, C; Lehikoinen, P; Müller, L; Någren, K; Swahn, CG1
Balster, RL; Jortani, SA; Mansbach, RS1
Vanover, KE; Weed, MR; Woolverton, WL1
Bergman, J1
Barnett, A; Ellinwood, EH; Guse, PA; Kanani, PM; Smith, WM1
Caltavuturo, C; Colli, E; Consolo, S; Di Chiara, G; Recchia, M1
Clarke, L; Coffin, V; Cornish, J; Glue, P; Kampman, K; Kaplan, HL; O'Brien, CP; Poole, S; Romach, MK; Sellers, EM; Somer, GR1
Platt, DM; Rowlett, JK; Spealman, RD1
Fischman, MW; Foltin, RW; Haney, M; Ward, AS1
Bigelow, GE; Donny, EC; Nann-Vernotica, E; Walsh, SL1
Elliot, EE; Katz, JL; Sibley, DR1
Barrett, AC; Caine, SB; Dohrmann, JM; Miller, JR1
Barrett, AC; Caine, SB; Mello, NK; Negus, SS1
Caine, SB; Hall, FS; Thomsen, M; Uhl, GR1

Trials

3 trial(s) available for cocaine and ecopipam

ArticleYear
Attenuation of the euphoric effects of cocaine by the dopamine D1/D5 antagonist ecopipam (SCH 39166)
    Archives of general psychiatry, 1999, Volume: 56, Issue:12

    Topics: Adult; Behavior, Addictive; Benzazepines; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Euphoria; Female; Humans; Male; Receptors, Dopamine; Reward

1999
Effects of ecopipam, a selective dopamine D1 antagonist, on smoked cocaine self-administration by humans.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Administration, Inhalation; Adult; Benzazepines; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Hemodynamics; Humans; Male; Psychiatric Status Rating Scales; Receptors, Dopamine D1; Self Administration

2001
Repeated administration of the D1/5 antagonist ecopipam fails to attenuate the subjective effects of cocaine.
    Psychopharmacology, 2001, Volume: 155, Issue:4

    Topics: Adult; Benzazepines; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Receptors, Dopamine D1; Receptors, Dopamine D5; Smoking; Smoking Cessation; Surveys and Questionnaires

2001

Other Studies

13 other study(ies) available for cocaine and ecopipam

ArticleYear
Cocaine-antagonist effects of limited-efficacy D1 agonists.
    NIDA research monograph, 1992, Volume: 119

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Agents; Dopamine Antagonists; Receptors, Dopamine D1; Reinforcement Schedule; Saimiri

1992
Antagonism of behavioral effects of cocaine by selective dopamine receptor blockers.
    Psychopharmacology, 1990, Volume: 101, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Benzazepines; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Flupenthixol; Male; Receptors, Dopamine; Reinforcement Schedule; Saimiri

1990
Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:2

    Topics: Benzazepines; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cocaine; Dopamine Antagonists; Ephedrine; Hydrocarbons, Iodinated; Indicators and Reagents; Isotope Labeling; Magnetic Resonance Spectroscopy; Mesylates; Radioligand Assay; Selegiline; Tomography, Emission-Computed

1995
Discriminative stimulus effects of esteratic local anesthetics in squirrel monkeys.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Aminobenzoates; Anesthetics, Local; Animals; Benzazepines; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Propanolamines; Raclopride; Regression Analysis; Saimiri; Salicylamides; Substance-Related Disorders

1995
Reinforcing effect of the D1 dopamine agonist SKF 81297 in rhesus monkeys.
    Psychopharmacology, 1993, Volume: 113, Issue:1

    Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Macaca mulatta; Receptors, Dopamine D1; Reinforcement, Psychology; Self Administration; Synaptic Transmission

1993
Preclinical assessment of cocaine antagonist drugs in squirrel monkeys.
    NIDA research monograph, 1994, Volume: 145

    Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Reinforcement Schedule; Saimiri

1994
Acute deleterious effects of cocaine on cardiac conduction, hemodynamics, and ventricular fibrillation threshold: effects of interaction with a selective dopamine D1 antagonist SCH 39166.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:1

    Topics: Animals; Benzazepines; Blood Pressure; Cocaine; Dogs; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electrocardiography; Electrophysiology; Heart Conduction System; Heart Rate; Hemodynamics; Receptors, Dopamine D1; Ventricular Fibrillation

1998
Different sensitivity of in vivo acetylcholine transmission to D1 receptor stimulation in shell and core of nucleus accumbens.
    Neuroscience, 1999, Volume: 89, Issue:4

    Topics: Acetylcholine; Animals; Benzazepines; Cocaine; Dextroamphetamine; Dopamine Agonists; Dopamine Antagonists; Female; Microdialysis; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Synaptic Transmission; Tetrodotoxin

1999
Dissociation of cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Catalepsy; Cocaine; Discrimination Learning; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Muscle Rigidity; Receptors, Dopamine D1; Saimiri

2000
Locomotor and discriminative-stimulus effects of cocaine in dopamine D5 receptor knockout mice.
    Psychopharmacology, 2003, Volume: 169, Issue:2

    Topics: Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Heterozygote; Male; Mice; Mice, Knockout; Motor Activity; Receptors, Dopamine D1; Receptors, Dopamine D5

2003
Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self-administration and food maintained responding in rats.
    Neuropharmacology, 2004, Volume: 47 Suppl 1

    Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Food; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reinforcement, Psychology; Salicylamides; Self Administration; Tetrahydronaphthalenes

2004
Effect of GABA agonists and GABA-A receptor modulators on cocaine- and food-maintained responding and cocaine discrimination in rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2

    Topics: Animals; Benzazepines; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Food; GABA Agonists; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Self Administration

2005
Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-28, Volume: 29, Issue:4

    Topics: Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Exploratory Behavior; Mice; Mice, Knockout; Reinforcement Schedule; Self Administration; Serotonin Plasma Membrane Transport Proteins

2009