cocaine has been researched along with ecgonine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (15.00) | 18.7374 |
| 1990's | 16 (40.00) | 18.2507 |
| 2000's | 12 (30.00) | 29.6817 |
| 2010's | 6 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ball, WJ; Farr, CD; Norman, AB; Paula, S; Tabet, MR | 1 |
| Akiyama, S; Kuroda, N; Nakashima, K; Okamoto, M; Yamaguchi, M; Yoshida, K | 1 |
| Brogan, WC; Glamann, DB; Hillis, LD; Lange, RA | 1 |
| Delafuente, JC; DeVane, CL | 1 |
| Madden, JA; Powers, RH | 1 |
| Eldefrawi, ME; Fox, KM; Kline, RH; Wright, J | 1 |
| de Kanel, J; Dunlap, L; Hall, TD | 1 |
| Palatý, V | 1 |
| Robinson, K; Smith, RN | 1 |
| Loughlin, KR; Zhang, H | 1 |
| Baum, I; Erzouki, HK; Goldberg, SR; Schindler, CW | 1 |
| Christian, GD; Logan, BK; Peterson, KL | 1 |
| Carballo, DD; Falk, PM; Sabater, RT | 1 |
| De Giovanni, N; Strano Rossi, S | 1 |
| Fukui, M; Igarashi, K; Kasuya, F; Nakajima, K; Nishikawa, M; Tatsuno, M; Tsuchihashi, H | 1 |
| Covert, RF; Madden, JA; Schreiber, MD; Torgerson, LJ | 1 |
| Kidwell, DA | 1 |
| Colassis, T; Giroud, C; Ottinger, E; Rivier, L | 1 |
| Britt, AJ; Bruce, NC; Lister, DL; Lowe, CR; Sproulé, RF | 1 |
| Logan, BK; Smirnow, D | 1 |
| Allen, DL; Oliver, JS | 1 |
| Klingmann, A; Mattern, R; Pötsch, L; Skopp, G | 1 |
| Logan, BK | 1 |
| Baird, TJ; Briscoe, RJ; Cabrera, C; Jeanville, PM; Landry, DW; Woods, JH | 1 |
| Aderjan, R; Klingmann, A; Skopp, G | 1 |
| CHILTON, J; STENLAKE, JB | 1 |
| AVICO, U | 1 |
| Lunte, C; McDonald, S | 1 |
| LEVY, J; ZISSMANN, E | 1 |
| Abdel-Rahman, MS; Turkall, R; Visalli, T | 1 |
| Hoelzle, C; Sachs, H; Scheufler, F; Thieme, D; Uhl, M | 1 |
| Atack, JR; Dawson, GR; Morris, HV; Reynolds, DS; Rosahl, TW; Stephens, DN | 1 |
| Jagerdeo, E; Lebeau, MA; Montgomery, MA; Sibum, M | 1 |
| Bervoets, L; Blust, R; Charlier, C; Covaci, A; Dubois, N; Jorens, PG; Meulemans, H; Neels, H; Pecceu, B; Theunis, L; van Nuijs, AL | 1 |
| Brettell, TA; Lalancette, RA; Thompson, HW; Wood, MR | 1 |
| Cone, EJ; Darwin, WD; Huestis, MA; Paul, BD; Shimomura, E; Smith, ML | 1 |
| Bisceglia, KJ; Lippa, KA; Roberts, AL | 1 |
| Cao, F; Liang, C; Ni, C; Rao, Y; Wang, R; Wang, X; Xiong, L; Ye, H; Zeng, L; Zhang, Y | 1 |
| Bisceglia, KJ; Lippa, KA | 1 |
| Cabanillas, LM; Fernández, N; Olivera, NM; Quiroga, PN | 1 |
1 trial(s) available for cocaine and ecgonine
| Article | Year |
|---|---|
Recurrent coronary vasoconstriction caused by intranasal cocaine: possible role for metabolites.
Topics: Administration, Intranasal; Adult; Aged; Cineangiography; Cocaine; Coronary Angiography; Coronary Vessels; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Recurrence; Vasoconstriction | 1992 |
39 other study(ies) available for cocaine and ecgonine
| Article | Year |
|---|---|
Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay | 2004 |
Preparation of a fluorescent derivative of benzoylecgonine, and preliminary studies of its application to the analysis of urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Fluorescent Dyes; Humans; Quinoxalines; Reproducibility of Results; Spectrometry, Fluorescence | 1992 |
Immunologic effects of cocaine and related alkaloids.
Topics: Chemotaxis, Leukocyte; Cocaine; Concanavalin A; Humans; Immunity, Cellular; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocyte Activation; Neutrophils | 1991 |
Effect of cocaine and cocaine metabolites on cerebral arteries in vitro.
Topics: Animals; Cats; Cerebral Arteries; Cocaine; Female; In Vitro Techniques; Male; Norepinephrine; Serotonin; Vasoconstrictor Agents | 1990 |
Synthesis of 3-arylecgonine analogues as inhibitors of cocaine binding and dopamine uptake.
Topics: Animals; Biological Transport; Cattle; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Indicators and Reagents; Molecular Structure; Spectrum Analysis; Structure-Activity Relationship; Synaptosomes | 1990 |
Extending the detection limit of the TDx fluorescence polarization immunoassay for benzoylecgonine in urine.
Topics: Autoanalysis; Cocaine; False Negative Reactions; Fluorescence Polarization; Humans; Immunoassay; Mathematics; Solanine; Statistics as Topic; Substance-Related Disorders | 1989 |
Release of vesicular noradrenaline in the rat tail artery induced by cocaine.
Topics: Animals; Arteries; Calcium; Cocaine; Desipramine; Dose-Response Relationship, Drug; Male; Methoxyhydroxyphenylglycol; Microscopy, Electron; Monoamine Oxidase; Norepinephrine; Rats; Rats, Inbred Strains; Tail | 1988 |
Radioimmunoassay of benzoylecgonine in samples of forensic interest.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cocaine; Cross Reactions; Humans; Mass Spectrometry; Radioimmunoassay; Reagent Kits, Diagnostic | 1984 |
The effect of cocaine and its metabolites on Sertoli cell function.
Topics: Androgen-Binding Protein; Animals; Cells, Cultured; Cocaine; In Vitro Techniques; Male; Narcotics; Rats; Rats, Sprague-Dawley; Sertoli Cells; Time Factors; Transferrin | 1996 |
Comparison of the effects of cocaine and its metabolites on cardiovascular function in anesthetized rats.
Topics: Animals; Cocaine; Electrocardiography; Electrophysiology; Hemodynamics; Infusions, Intravenous; Male; Rats; Structure-Activity Relationship | 1993 |
Detection of cocaine and its polar transformation products and metabolites in human urine.
Topics: Biotransformation; Calibration; Cation Exchange Resins; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reproducibility of Results; Substance-Related Disorders | 1995 |
Response of the human hepatic tissue cultures Hep-G2 and WRL-68 to cocaine.
Topics: Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell Line; Chromatography, Gas; Cocaine; Humans; Liver; Mass Spectrometry; Tumor Cells, Cultured | 1995 |
Simultaneous detection of cocaine and heroin metabolites in urine by solid-phase extraction and gas chromatography-mass spectrometry.
Topics: Cocaine; Deuterium; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Hydrogen-Ion Concentration; Microchemistry; Morphine Derivatives; Reproducibility of Results; Sensitivity and Specificity | 1994 |
The analysis of cocaine and its metabolites by liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry (LC/APCI-MS).
Topics: Chromatography, High Pressure Liquid; Cocaine; Evaluation Studies as Topic; Forensic Medicine; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion; Substance Abuse Detection | 1994 |
Effects of cocaine, benzoylecgonine, and cocaine metabolites in cannulated pressurized fetal sheep cerebral arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Catheterization; Cerebral Arteries; Cocaine; Female; In Vitro Techniques; Pregnancy; Receptors, Adrenergic, alpha-1; Sheep; Vasoconstriction | 1994 |
Analysis of phencyclidine and cocaine in human hair by tandem mass spectrometry.
Topics: Cocaine; Hair; Humans; Mass Spectrometry; Phencyclidine; Substance-Related Disorders | 1993 |
[Cocaine and alcohol: an explosive cocktail!].
Topics: Cocaine; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Neurotransmitter Uptake Inhibitors; Substance-Related Disorders | 1993 |
Degradation of cocaine by a mixed culture of Pseudomonas fluorescens MBER and Comamonas acidovorans MBLF.
Topics: Benzoates; Benzoic Acid; Biodegradation, Environmental; Carboxylic Ester Hydrolases; Cocaine; Coenzyme A Ligases; Gram-Negative Aerobic Bacteria; Models, Chemical; Pseudomonas fluorescens | 1996 |
Analysis of ecgonine and other cocaine biotransformation products in postmortem whole blood by protein precipitation-extractive alkylation and GC-MS.
Topics: Alkylation; Amines; Biotransformation; Carboxylic Acids; Cocaine; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reference Standards; Solvents; Structure-Activity Relationship | 1996 |
The application of supercritical fluid extraction to cocaine and its metabolites in blood and urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reproducibility of Results | 2000 |
In vitro stability of cocaine in whole blood and plasma including ecgonine as a target analyte.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Plasma; Specimen Handling; Temperature | 2001 |
Ecgonine is an important marker for cocaine use in inadequately preserved specimens.
Topics: Biomarkers; Cocaine; Cocaine-Related Disorders; Humans; Specimen Handling | 2001 |
A catalytic antibody against cocaine attenuates cocaine's cardiovascular effects in mice: a dose and time course analysis.
Topics: Animals; Antibodies, Monoclonal; Blood Pressure; Cocaine; Dose-Response Relationship, Drug; Hemodynamics; Indicators and Reagents; Male; Mice; Mice, Inbred BALB C; Time Factors | 2001 |
Analysis of cocaine, benzoylecgonine, ecogonine methyl ester, and ecgonine by high-pressure liquid chromatography-API mass spectrometry and application to a short-term degradation study of cocaine in plasma.
Topics: Artifacts; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Humans; Hydrolysis; Mass Spectrometry; Narcotics; Sensitivity and Specificity; Specimen Handling; Time Factors | 2001 |
Dissociation constants of some compounds related to lysergic acid; Beta-dimethylaminopropionic acid, dihydroarecaidine, ecgonine and their derivatives.
Topics: Alanine; Cardiovascular Agents; Cocaine; Ergot Alkaloids; Lysergic Acid; Niacin; Nicotinic Acids | 1955 |
[ON THE OPTIC ROTATION OF ECGONINE AND ANHYDROECGONINE].
Topics: Chemistry Techniques, Analytical; Coca; Cocaine; Eye; Rotation | 1963 |
Determination of the dermal penetration of esterom components using microdialysis sampling.
Topics: Administration, Topical; Animals; Benzoic Acid; Cocaine; Esterification; Female; Microdialysis; Pharmaceutical Solutions; Rats; Skin Absorption | 2003 |
[Determination of slight quantities of cocaine in presence of ecgonine].
Topics: Cocaine; Humans | 1950 |
Gender differences in cocaine pharmacokinetics in CF-1 mice.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Female; Indicators and Reagents; Male; Mice; Sex Characteristics; Tissue Distribution | 2005 |
Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination.
Topics: Cocaine; Discriminant Analysis; Dopamine Uptake Inhibitors; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection | 2008 |
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Hyperkinesis; Mice; Mice, Knockout; Midazolam; Motor Activity; Protein Subunits; Receptors, GABA-A | 2008 |
An automated SPE/LC/MS/MS method for the analysis of cocaine and metabolites in whole blood.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2008 |
Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium.
Topics: Adolescent; Adult; Belgium; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Environmental Monitoring; Epidemiological Monitoring; Humans; Middle Aged; Narcotics; Substance Abuse Detection; Waste Disposal, Fluid; Water Pollutants, Chemical; Young Adult | 2009 |
The hydrated and anhydrous gold(III) tetrachloride salts of L-ecgonine, an important forensic toxicology marker for cocaine.
Topics: Cocaine; Crystallography, X-Ray; Forensic Toxicology; Gold Compounds; Humans; Molecular Structure; Salts; Water | 2010 |
Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine.
Topics: Adult; Biomarkers; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Male; Substance Abuse Detection | 2010 |
A hydrolysis procedure for the analysis of total cocaine residues in wastewater.
Topics: Chromatography, Liquid; Cocaine; Humans; Hydrolysis; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Determination of ecgonine and seven other cocaine metabolites in human urine and whole blood by ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Solid Phase Extraction; Tandem Mass Spectrometry | 2013 |
Stability of cocaine and its metabolites in municipal wastewater--the case for using metabolite consolidation to monitor cocaine utilization.
Topics: Cocaine; Drug Utilization; Environmental Monitoring; Hydrogen-Ion Concentration; Hydrolysis; Sewage; Wastewater; Water Pollutants, Chemical | 2014 |
Optimization and validation of simultaneous analyses of ecgonine, cocaine, and seven metabolites in human urine by gas chromatography-mass spectrometry using a one-step solid-phase extraction.
Topics: Cocaine; Data Accuracy; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Solid Phase Extraction; Substance Abuse Detection | 2019 |