cocaine and dynorphins

cocaine has been researched along with dynorphins in 82 studies

Research

Studies (82)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.44)	18.7374
1990's	33 (40.24)	18.2507
2000's	32 (39.02)	29.6817
2010's	14 (17.07)	24.3611
2020's	1 (1.22)	2.80

Authors

Authors	Studies
Herkenham, M; Hurd, YL	2
Kameyama, T; Kamiya, T; Toyoshi, T; Ukai, M	1
Brown, EE; Fibiger, HC; Finlay, JM; Gerfen, CR; Hurd, YL	1
Bush, LG; Gibb, JW; Hanson, GR; Johnson, M	1
Bush, L; Gibb, JW; Hanson, GR; Johnson, M; Smiley, PL	1
Sivam, SP	1
Bush, LG; Gibb, JW; Hanson, GR; Johnson, M; Midgley, LP	1
Gerfen, CR; Steiner, H	2
Moss, IR; Zhang, C	1
Daunais, JB; McGinty, JF	3
Daunais, JB; McGinty, JF; Roberts, DC	2
Gibb, JW; Hanson, GR; Johnson, M; Merchant, K; Singh, N	1
Daunais, JB; Helton, TE; McGinty, JF	1
Kameyama, T; Mizutani, M; Ukai, M	1
Caron, MG; Giros, B; Jaber, M; Jones, SR; Wightman, RM	1
Ho, A; Kreek, MJ; Maggos, CE; Spangler, R; Yuferov, V; Zhou, Y	1
Elibol, B; Graybiel, AM; Moratalla, R; Vallejo, M	1
Drago, J; Gerfen, CR; Steiner, H; Westphal, H	1
Ho, A; Kreek, MJ; Maggos, CE; Spangler, R; Zhou, Y; Zlobin, A	1
Chai, L; Choi, WS; Rönnekleiv, OK	1
Rea, W; Shippenberg, TS	1
Gerfen, CR; Keefe, KA; Steiner, H	1
Daunais, JB; Davies, HM; Hart, SL; Hedgecock-Rowe, A; Matasi, JJ; Porrino, LJ; Thornley, C	1
Besson, MJ; Mathieu-Kia, AM	1
Chai, L; Choi, WS; Fang, Y; Rønnekleiv, OK	1
Brodkin, ES; Carlezon, WA; Duman, RS; Hiroi, N; Lane-Ladd, SB; Nestler, EJ; Neve, RL; Olson, VG; Thome, J	1
Cappendijk, SL; Hurd, YL; Nylander, I; Terenius, L; van Ree, JM	1
Hurd, YL; Pontén, M; Svensson, P	1
Alburges, ME; Hanson, GR	1
Lucas, LR; McEwen, BS; Pompei, P	1
Cuéllar, B; Gardier, AM; Graybiel, AM; Guibert, B; Lebrec, H; Moratalla, R; Sacerdote, M	1
Carta, AR; Gerfen, CR; Steiner, H	1
Brené, S; Olson, L; Thorén, P; Werme, M	1
Adams, DH; Hanson, GR; Keefe, KA	2
Alvarez Fischer, D; Ferger, B; Gross, S; Kuschinsky, K; Schäfer, MK; Weihe, E; Westermann, R	1
Ho, A; Kreek, MJ; LaForge, KS; Spangler, R; Yuferov, V; Zhou, Y	1
Carlezon, WA; Carlson, RR; Konradi, C; Nestler, EJ; Neve, RL; Pliakas, AM	1
Chen, J; Duman, RS; Kelz, MB; Nestler, EJ; Newton, SS; Sakai, N; Steffen, C; Thome, J	1
Ho, A; Kreek, MJ; Schlussman, SD; Sora, I; Spangler, R; Uhl, GR; Yuferov, VP; Zhou, Y	1
Chin, J; Festa, ED; Jenab, S; Niyomchai, T; Perrotti, LI; Quinones-Jenab, V; Russo, SJ	1
Hurd, YL	1
Steiner, H; Sun, W; Willuhn, I	1
Colby, CR; Nestler, EJ; Self, DW; Steffen, C; Whisler, K	1
Ho, A; Kreek, MJ; LaForge, KS; Schlussman, SD; Yuferov, V; Zhang, Y	1
Brandon, CL; Steiner, H	1
Festa, ED; Inturrisi, CE; Jenab, S; Quinones-Jenab, V; Russo, SJ; Wu, HB	1
Blendy, JA; Kuo, YC; Walters, CL	1
Butelman, ER; Ho, A; Kreek, MJ; Schlussman, SD; Zhang, Y	1
Ho, A; Kreek, MJ; Mantsch, JR; Mathieu-Kia, AM; Yuferov, V	1
Adams, DH; Hanson, GR; Horner, KA; Keefe, KA	1
Lou, D; Sharp, FR; Tang, Y; Xu, M; Zhang, D; Zhang, J; Zhang, L; Zhang, Q	1
Bailey, A; Ho, A; Kreek, MJ; Schlussman, SD; Zhou, Y	1
Deroche-Gamonet, V; Izawa, R; Jaber, M; Kellendonk, C; Le Moal, M; Piazza, PV; Sillaber, I; Tronche, F	1
Steiner, H; Willuhn, I	1
Chefer, VI; Shippenberg, TS	1
Horner, KA; Keefe, KA	1
Candeletti, S; D'Addario, C; Di Benedetto, M; Izenwasser, S; Romualdi, P	1
Bailey, A; Kitchen, I; Racz, I; Yoo, JH; Zimmer, A	1
Chefer, VI; Shippenberg, TS; Zapata, A	1
Choi, JC; Cui, CL; Han, JS; Ho, A; Kreek, MJ; Schlussman, SD; Zhou, Y	1
Goddard, B; Jacklin, D; Kreek, MJ; Leri, F; Levy, A; Zhou, Y	1
Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK	1
Chavkin, C; Li, S; Schindler, AG	1
Dong, Y; Mu, P; Neumann, PA; Panksepp, J; Schlüter, OM	1
Alburges, ME; Fleckenstein, AE; Hanson, GR; Hoonakker, AJ; Horner, KA	1
Carmichael, B; Cummins, E; Kreek, MJ; Leri, F; Zhou, Y	1
An, S; Gu, J; Guo, F; Li, J; Liu, N; Lu, K; Zhang, L	1
Butelman, ER; Ho, A; Kreek, MJ; Rabkin, J; Schlussman, SD; Zhang, Y	1
Chavkin, C; Chavkin, NW; Gustin, RM; Hagan, CE; Lemos, JC; Messinger, DI; Neumaier, JF; Schattauer, SS; Schindler, AG; Shankar, H; Smith, JS	1
Carlezon, WA; Muschamp, JW	1
Carneiro-de-Oliveira, PE; Cruz, FC; Leão, RM; Planeta, CS; Rossetto, DB; Valentini, SR; Zanelli, CF	1
Bastias del Carmen Candia, S; Candeletti, S; Caputi, FF; Carretta, D; Cavina, C; D'Addario, C; Di Benedetto, M; Romualdi, P	1
Borgland, SL; Carlezon, WA; Hassinger, LC; Hollander, JA; Kamenecka, TM; Kenny, PJ; Muschamp, JW; Onvani, S; Thompson, JL; Voren, G	1
George, O; Kallupi, M; Martin-Fardon, R; Matzeu, A; Schweitzer, P	1
Carson, RE; Chang, D; Foltin, R; Grassetti, A; Huang, Y; Lin, SF; Martinez, D; Matuskey, D; Nabulsi, N; Ropchan, J; Salling, M; Slifstein, M; Urban, N; Zheng, MQ	1
Bernat, N; Inbar, D; Inbar, K; Kupchik, YM; Levi, LA; Odesser, T	1

Reviews

4 review(s) available for cocaine and dynorphins

Article	Year
Sensitization to the behavioral effects of cocaine: modulation by dynorphin and kappa-opioid receptor agonists. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:3 Topics: Animals; Cocaine; Dynorphins; Locomotion; Receptors, Opioid, kappa	1997
The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse. Annals of the New York Academy of Sciences, 1999, Jun-29, Volume: 877 Topics: Amphetamine; Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dynorphins; Female; Gene Expression Regulation; Male; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Self Administration	1999
Dynorphin and the pathophysiology of drug addiction. Pharmacology & therapeutics, 2007, Volume: 116, Issue:2 Topics: Alcoholism; Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Dynorphins; Ethanol; Humans; Receptors, Opioid, kappa; Substance-Related Disorders; Up-Regulation	2007
Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation. Cold Spring Harbor perspectives in medicine, 2013, Feb-01, Volume: 3, Issue:2 Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Dynorphins; Gene Expression Regulation; Humans; Mammals; Morphine; Motivation; Narcotics; Nucleus Accumbens; Receptors, Neurotransmitter; Reward; Signal Transduction; Substance-Related Disorders; Transcriptional Activation	2013

Other Studies

78 other study(ies) available for cocaine and dynorphins

Article	Year
Influence of a single injection of cocaine, amphetamine or GBR 12909 on mRNA expression of striatal neuropeptides. Brain research. Molecular brain research, 1992, Volume: 16, Issue:1-2 Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dynorphins; Enkephalins; In Situ Hybridization; Male; Neuropeptides; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P	1992
Systemic administration of dynorphin A(1-13) markedly inhibits different behavioural responses induced by cocaine in the mouse. Neuropharmacology, 1992, Volume: 31, Issue:9 Topics: Analgesics; Animals; Behavior, Animal; Benzomorphans; Cocaine; Dynorphins; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Motor Activity; Narcotic Antagonists; Peptide Fragments; Substance Withdrawal Syndrome	1992
Cocaine self-administration differentially alters mRNA expression of striatal peptides. Brain research. Molecular brain research, 1992, Volume: 13, Issue:1-2 Topics: Animals; Autoradiography; Caudate Nucleus; Cocaine; Corpus Striatum; Deoxyadenine Nucleotides; Dynorphins; Enkephalins; Gene Expression; Male; Oligonucleotide Probes; Rats; Reference Values; RNA, Messenger; Self Administration; Substance P; Sulfur Radioisotopes	1992
Role of N-methyl-D-aspartate (NMDA) receptors in the response of extrapyramidal neurotensin and dynorphin A systems to cocaine and GBR 12909. Biochemical pharmacology, 1991, Feb-15, Volume: 41, Issue:4 Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dynorphins; Male; Neurotensin; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Substantia Nigra	1991
Effects of cocaine on extrapyramidal and limbic dynorphin systems. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3 Topics: Animals; Benzazepines; Cocaine; Dopamine Antagonists; Dynorphins; Extrapyramidal Tracts; Limbic System; Male; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine	1990
Cocaine selectively increases striatonigral dynorphin levels by a dopaminergic mechanism. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Corpus Striatum; Dopamine; Dynorphins; Endorphins; Enkephalin, Methionine; Hydroxyindoleacetic Acid; Neuropeptides; Rats; Receptors, Dopamine; Serotonin; Substance P; Substantia Nigra	1989
Comparison of responses by neuropeptide systems in rat to the psychotropic drugs, methamphetamine, cocaine and PCP. NIDA research monograph, 1989, Volume: 95 Topics: Animals; Brain; Cocaine; Corpus Striatum; Dopamine; Dynorphins; Methamphetamine; Neurotensin; Nucleus Accumbens; Phencyclidine; Rats; Receptors, Dopamine; Substance P	1989
Cocaine-induced c-fos messenger RNA is inversely related to dynorphin expression in striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1993, Volume: 13, Issue:12 Topics: Animals; Cerebral Cortex; Cocaine; Corpus Striatum; Dynorphins; Enkephalins; Gene Expression; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance P	1993
Age-related mu-, delta-and kappa-opioid ligands in respiratory-related brain regions of piglets: effect of prenatal cocaine. Brain research. Developmental brain research, 1995, Jul-14, Volume: 87, Issue:2 Topics: Aging; Animals; Animals, Newborn; beta-Endorphin; Brain Stem; Cocaine; Dynorphins; Enkephalin, Methionine; Female; Ligands; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Respiration; Swine	1995
Cocaine binges differentially alter striatal preprodynorphin and zif/268 mRNAs. Brain research. Molecular brain research, 1995, Volume: 29, Issue:2 Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Corpus Striatum; Disease Models, Animal; DNA-Binding Proteins; Drug Administration Schedule; Dynorphins; Early Growth Response Protein 1; Enkephalins; Immediate-Early Proteins; Male; Nerve Tissue Proteins; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors	1995
Short-term cocaine self administration alters striatal gene expression. Brain research bulletin, 1995, Volume: 37, Issue:5 Topics: Animals; Cocaine; Dynorphins; Enkephalins; Gene Expression; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Neostriatum; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Self Administration	1995
Molecular alterations in the neostriatum of human cocaine addicts. Synapse (New York, N.Y.), 1993, Volume: 13, Issue:4 Topics: Adolescent; Adult; Autoradiography; Cocaine; Dynorphins; Enkephalins; Female; Histocytochemistry; Humans; In Situ Hybridization; Male; Middle Aged; Neostriatum; Nucleus Accumbens; Putamen; Receptors, Dopamine; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Substance P; Substance-Related Disorders	1993
Dynorphin opioid inhibition of cocaine-induced, D1 dopamine receptor-mediated immediate-early gene expression in the striatum. The Journal of comparative neurology, 1995, Mar-06, Volume: 353, Issue:2 Topics: Animals; Base Sequence; Benzazepines; Cocaine; Corpus Striatum; Dynorphins; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Infusions, Parenteral; Male; Molecular Sequence Data; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Opioid, kappa; Transcriptional Activation	1995
The role of NMDA receptor systems in neuropeptide responses to stimulants of abuse. Drug and alcohol dependence, 1995, Volume: 37, Issue:2 Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dynorphins; Methamphetamine; N-Methylaspartate; Neuropeptides; Neurotensin; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission	1995
Acute and chronic cocaine administration differentially alters striatal opioid and nuclear transcription factor mRNAs. Synapse (New York, N.Y.), 1994, Volume: 18, Issue:1 Topics: Animals; Cell Nucleus; Cocaine; Dynorphins; Endorphins; Enkephalins; Gene Expression Regulation; Image Processing, Computer-Assisted; In Situ Hybridization; Male; Neostriatum; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Transcription Factors	1994
Convulsant doses of cocaine alter immediate early gene and opioid peptide expression in rat limbic forebrain. Brain research. Molecular brain research, 1993, Volume: 20, Issue:3 Topics: Animals; Cocaine; Convulsants; DNA-Binding Proteins; Dynorphins; Early Growth Response Protein 1; Enkephalins; Gene Expression Regulation; Immediate-Early Proteins; In Situ Hybridization; Kindling, Neurologic; Limbic System; Male; Nerve Tissue Proteins; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Seizures; Time Factors; Transcription Factors	1993
Opioid peptides selective for receptor types modulate cocaine-induced behavioral responses in mice. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:3 Topics: Animals; Behavior, Animal; Cocaine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Naltrexone; Opioid Peptides	1994
Cocaine self-administration increases preprodynorphin, but not c-fos, mRNA in rat striatum. Neuroreport, 1993, Volume: 4, Issue:5 Topics: Animals; Cell Nucleus; Cocaine; Corpus Striatum; Dynorphins; Gene Expression; Genes, fos; In Situ Hybridization; Male; Neurons; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; Reinforcement Schedule; RNA, Messenger; Self Administration	1993
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature, 1996, Feb-15, Volume: 379, Issue:6566 Topics: Amphetamine; Animals; Carrier Proteins; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dynorphins; Enkephalins; Female; Gene Expression Regulation; Gene Targeting; Locomotion; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Protein Precursors; Rats	1996
The effects of D1 or D2 dopamine receptor blockade on zif/268 and preprodynorphin gene expression in rat forebrain following a short-term cocaine binge. Brain research. Molecular brain research, 1996, Volume: 35, Issue:1-2 Topics: Animals; Autoradiography; Benzazepines; Cerebral Cortex; Cocaine; Corpus Striatum; DNA-Binding Proteins; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dynorphins; Early Growth Response Protein 1; Gene Expression; Immediate-Early Proteins; In Situ Hybridization; Male; Nucleus Accumbens; Organ Specificity; Prosencephalon; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Stereotyped Behavior; Sulfur Radioisotopes; Sulpiride; Synapses; Time Factors; Transcription Factors; Zinc Fingers	1996
Regulation of kappa opioid receptor mRNA in the rat brain by "binge' pattern cocaine administration and correlation with preprodynorphin mRNA. Brain research. Molecular brain research, 1996, Volume: 38, Issue:1 Topics: Animals; Brain; Caudate Nucleus; Chemical Precipitation; Cocaine; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dynorphins; Gene Expression Regulation; Male; Protein Precursors; Putamen; Rats; Rats, Inbred F344; Receptors, Opioid, kappa; RNA, Messenger; Substantia Nigra; Ventral Tegmental Area	1996
Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal. Neuron, 1996, Volume: 17, Issue:1 Topics: Animals; Blotting, Western; Caudate Nucleus; Cocaine; Corpus Striatum; Dynorphins; Immunohistochemistry; Interneurons; Male; Nerve Net; Neurons; Phenotype; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Putamen; Rats; Rats, Sprague-Dawley; Synaptic Transmission	1996
D1 dopamine receptor-deficient mouse: cocaine-induced regulation of immediate-early gene and substance P expression in the striatum. Neuroscience, 1996, Volume: 74, Issue:3 Topics: Animals; Base Sequence; Body Weight; Brain; Cocaine; Corpus Striatum; DNA-Binding Proteins; Dynorphins; Early Growth Response Protein 1; Enkephalins; Gene Expression Regulation; Genes, Immediate-Early; Heterozygote; Homozygote; Immediate-Early Proteins; In Situ Hybridization; Mice; Mice, Knockout; Molecular Sequence Data; Oligonucleotide Probes; Organ Size; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; RNA, Messenger; Substance P; Transcription Factors; Transcription, Genetic; Transcriptional Activation	1996
Dopamine antagonist and "binge' cocaine effects on rat opioid and dopamine transporter mRNAs. Neuroreport, 1996, Sep-02, Volume: 7, Issue:13 Topics: Analysis of Variance; Animals; Benzazepines; Brain; Carrier Proteins; Cocaine; DNA Primers; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Drug Administration Schedule; Dynorphins; Enkephalins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Polymerase Chain Reaction; Protein Precursors; Rats; Rats, Inbred F344; Receptors, Opioid, kappa; RNA, Messenger; Substance-Related Disorders; Sulpiride; Transcription, Genetic	1996
Maternal cocaine treatment alters dynorphin and enkephalin mRNA expression in brains of fetal rhesus macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Feb-01, Volume: 17, Issue:3 Topics: Animals; Brain; Cocaine; Dynorphins; Enkephalins; Female; Gene Expression Regulation; Macaca mulatta; Narcotics; Pregnancy; Protein Precursors; RNA, Messenger	1997
Dopamine-mediated gene regulation in the striatum. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cocaine; Corpus Striatum; Dopamine; Dynorphins; Enkephalins; Gene Expression Regulation; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P; Transcription, Genetic	1998
Alterations in behavior and opioid gene expression induced by the novel tropane analog WF-31. Brain research. Molecular brain research, 1997, Oct-15, Volume: 50, Issue:1-2 Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Fluoxetine; Gene Expression; Genome; Male; Motor Activity; Protein Precursors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Tropanes	1997
Repeated administration of cocaine, nicotine and ethanol: effects on preprodynorphin, preprotachykinin A and preproenkephalin mRNA expression in the dorsal and the ventral striatum of the rat. Brain research. Molecular brain research, 1998, Volume: 54, Issue:1 Topics: Animals; Body Weight; Cocaine; Corpus Striatum; Drug Administration Schedule; Dynorphins; Enkephalins; Ethanol; In Situ Hybridization; Injections, Subcutaneous; Male; Nicotine; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tachykinins	1998
Changes in the midbrain-rostral forebrain dopamine circuitry in the cocaine-exposed primate fetal brain. Annals of the New York Academy of Sciences, 1998, Jun-21, Volume: 846 Topics: Amniotic Fluid; Animals; Body Weight; Brain; Cocaine; Dopamine; Dynorphins; Embryonic and Fetal Development; Enkephalins; Female; Gene Expression Regulation, Developmental; Macaca mulatta; Mesencephalon; Metabolic Clearance Rate; Neurons; Pregnancy; Prosencephalon; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Transcription, Genetic	1998
Regulation of cocaine reward by CREB. Science (New York, N.Y.), 1998, Dec-18, Volume: 282, Issue:5397 Topics: Animals; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Dynorphins; Gene Expression; Gene Expression Regulation; Gene Transfer Techniques; Genetic Vectors; Naltrexone; Narcotic Antagonists; Neurons; Nucleus Accumbens; Point Mutation; Rats; Receptors, Opioid, kappa; Reward; RNA, Messenger; Simplexvirus	1998
A heroin-, but not a cocaine-expecting, self-administration state preferentially alters endogenous brain peptides. European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3 Topics: Animals; Behavior, Animal; Brain; Cocaine; Dynorphins; Enkephalins; Heroin; Injections, Intravenous; Male; Neuropeptides; Radioimmunoassay; Rats; Rats, Wistar; Self Administration; Substance P; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors	1999
Ibogaine pretreatment dramatically enhances the dynorphin response to cocaine. Brain research, 1999, Nov-13, Volume: 847, Issue:1 Topics: Animals; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Dynorphins; Excitatory Amino Acid Antagonists; Ibogaine; Male; Neostriatum; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Substantia Nigra	1999
Correlates of deoxycorticosterone-induced salt appetite behavior and basal ganglia neurochemistry. Annals of the New York Academy of Sciences, 1999, Volume: 897 Topics: Animals; Appetite; Basal Ganglia; Carrier Proteins; Cocaine; Desoxycorticosterone; Dopamine Plasma Membrane Transport Proteins; Dynorphins; Enkephalins; Gene Expression Regulation; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nucleus Accumbens; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium, Dietary; Transcription, Genetic; Tyrosine 3-Monooxygenase	1999
Interaction between the serotoninergic and dopaminergic systems in d-fenfluramine-induced activation of c-fos and jun B genes in rat striatal neurons. Journal of neurochemistry, 2000, Volume: 74, Issue:4 Topics: Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Dynorphins; Fenfluramine; Gene Expression; Male; Methiothepin; Neurons; p-Chloroamphetamine; Phenotype; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Agents; Serotonin Antagonists; Synaptic Transmission	2000
Cocaine effects on gene regulation in the striatum and behavior: increased sensitivity in D3 dopamine receptor-deficient mice. Neuroreport, 2000, Aug-03, Volume: 11, Issue:11 Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dynorphins; Gene Expression Regulation; Head Movements; Mice; Mice, Knockout; Motor Activity; Neostriatum; Neurons; Nucleus Accumbens; Phenotype; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Stereotyped Behavior	2000
Running and cocaine both upregulate dynorphin mRNA in medial caudate putamen. The European journal of neuroscience, 2000, Volume: 12, Issue:8 Topics: Analgesics, Opioid; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Gene Expression; In Situ Hybridization; Male; Morphine; Naloxone; Narcotic Antagonists; Neostriatum; Rats; Rats, Inbred F344; Rats, Inbred Lew; RNA, Messenger; Running; Species Specificity; Substance P	2000
Cocaine and methamphetamine differentially affect opioid peptide mRNA expression in the striatum. Journal of neurochemistry, 2000, Volume: 75, Issue:5 Topics: Animals; Autoradiography; Cocaine; Corpus Striatum; Dynorphins; Enkephalins; In Situ Hybridization; Male; Methamphetamine; Nucleus Accumbens; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger	2000
Sensitization to the behavioural effects of cocaine: alterations in tyrosine hydroxylase or endogenous opioid mRNAs are not necessarily involved. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:3 Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Dynorphins; Enkephalins; In Situ Hybridization; Locomotion; Male; Microdialysis; Neurons; Nucleus Accumbens; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger; Tyrosine Transaminase	2001
Elevation of guinea pig brain preprodynorphin mRNA expression and hypothalamic-pituitary-adrenal axis activity by "binge" pattern cocaine administration. Brain research bulletin, 2001, May-01, Volume: 55, Issue:1 Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dynorphins; Guinea Pigs; Hypothalamo-Hypophyseal System; Male; Protein Precursors; RNA, Messenger; Up-Regulation	2001
Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Sep-15, Volume: 21, Issue:18 Topics: Animals; Cocaine; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Dynorphins; Gene Expression; Gene Transfer Techniques; Genes, Dominant; Genetic Vectors; Hypokinesia; Male; Microinjections; Motor Activity; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Simplexvirus; Swimming	2001
Inducible and brain region-specific CREB transgenic mice. Molecular pharmacology, 2002, Volume: 61, Issue:6 Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Cyclic AMP Response Element-Binding Protein; Doxycycline; Dynorphins; Gene Expression Regulation; Immunohistochemistry; Mice; Mice, Transgenic; Motor Activity; Transcription Factors	2002
Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Synapse (New York, N.Y.), 2002, Sep-15, Volume: 45, Issue:4 Topics: Animals; Cocaine; Corpus Striatum; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Frontal Lobe; Gene Expression; Hypothalamo-Hypophyseal System; Male; Medulla Oblongata; Mice; Mice, Knockout; Pituitary-Adrenal System; Pons; Pro-Opiomelanocortin; Protein Precursors; Receptors, Opioid, mu; RNA, Messenger	2002
Effects of cocaine on c-fos and preprodynorphin mRNA levels in intact and ovariectomized Fischer rats. Brain research bulletin, 2002, Volume: 58, Issue:3 Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Drug Administration Schedule; Dynorphins; Estrogens; Estrous Cycle; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Male; Neostriatum; Ovariectomy; Progesterone; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; RNA, Messenger; Sex Characteristics; Up-Regulation	2002
Distinct effects of methamphetamine and cocaine on preprodynorphin messenger RNA in rat striatal patch and matrix. Journal of neurochemistry, 2003, Volume: 84, Issue:1 Topics: Animals; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Dynorphins; Extracellular Space; Male; Methamphetamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger	2003
In situ hybridization with isotopic riboprobes for detection of striatal neuropeptide mRNA expression after dopamine stimulant administration. Methods in molecular medicine, 2003, Volume: 79 Topics: Animals; Antisense Elements (Genetics); Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Humans; In Situ Hybridization; Protein Precursors; Rats; RNA Probes; RNA, Messenger	2003
Topography of cocaine-induced gene regulation in the rat striatum: relationship to cortical inputs and role of behavioural context. The European journal of neuroscience, 2003, Volume: 17, Issue:5 Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dynorphins; Gene Expression Regulation; Genes, fos; In Situ Hybridization; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger	2003
Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Mar-15, Volume: 23, Issue:6 Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Doxycycline; Drug Administration Schedule; Dynorphins; Gene Expression; Mice; Mice, Transgenic; Motivation; Neurons; Organ Specificity; Proto-Oncogene Proteins c-fos; Reinforcement, Psychology; Self Administration; Substance P; Transgenes	2003
Acute 'binge' cocaine administration elevates dynorphin mRNA in the caudate putamen of C57BL/6J but not 129/J mice. Brain research, 2003, Jun-06, Volume: 974, Issue:1-2 Topics: Animals; Behavior, Animal; Caudate Nucleus; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Dynorphins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Protein Precursors; Putamen; RNA, Messenger; Species Specificity	2003
Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum. The European journal of neuroscience, 2003, Volume: 18, Issue:6 Topics: Anesthetics, Local; Animals; Autoradiography; Cell Count; Central Nervous System Stimulants; Cocaine; Corpus Striatum; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Early Growth Response Protein 1; Enkephalins; Gene Expression Regulation; Gene Silencing; Genes, fos; Immediate-Early Proteins; In Situ Hybridization; Male; Methylphenidate; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Substance P; Transcription Factors	2003
MK-801 attenuates cocaine induction of c-fos and preprodynorphin mRNA levels in Fischer rats. Brain research. Molecular brain research, 2003, Oct-07, Volume: 117, Issue:2 Topics: Anesthetics, Local; Animals; Cocaine; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Dynorphins; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; RNA, Messenger	2003
Differential distribution of CREB in the mesolimbic dopamine reward pathway. Journal of neurochemistry, 2003, Volume: 87, Issue:5 Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA; Dopamine; Dynorphins; Illicit Drugs; Limbic System; Mice; Mice, Mutant Strains; Morphine; Neural Pathways; Nucleus Accumbens; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Reward; Substance-Related Disorders; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2003
Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology, 2004, Volume: 172, Issue:4 Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine; Dynorphins; Male; Mice; Mice, Inbred C57BL; Microdialysis; Motor Activity; Neostriatum; Receptors, Opioid, kappa; Reward	2004
Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. Psychopharmacology, 2004, Volume: 175, Issue:1 Topics: Animals; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Extinction, Psychological; Male; Opioid Peptides; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recurrence; RNA, Messenger; Self Administration; Time Factors	2004
Blockade of stimulant-induced preprodynorphin mRNA expression in the striatal matrix by serotonin depletion. Neuroscience, 2005, Volume: 131, Issue:1 Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dynorphins; Gene Expression Regulation; Male; Methamphetamine; p-Chloroamphetamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin	2005
Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:8 Topics: Animals; Benzazepines; Blotting, Western; Caudate Nucleus; CD2 Antigens; Cocaine; Cyclin D; Cyclins; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dynorphins; Gene Expression; Gene Expression Regulation; Immunohistochemistry; Insulin-Like Growth Factor Binding Protein 6; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microarray Analysis; Nucleus Accumbens; Proteins; Receptors, Dopamine D1; Reverse Transcriptase Polymerase Chain Reaction; RGS Proteins; RNA, Messenger; Time Factors	2005
Steady-dose and escalating-dose "binge" administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats. Brain research bulletin, 2005, Oct-15, Volume: 67, Issue:3 Topics: Analysis of Variance; Animals; Behavior, Animal; Body Weight; Cocaine; Corpus Striatum; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Gene Expression Regulation; Male; Protein Precursors; Rats; Rats, Inbred F344; RNA, Messenger; Stereotyped Behavior; Time Factors	2005
Gene expression regulation following behavioral sensitization to cocaine in transgenic mice lacking the glucocorticoid receptor in the brain. Neuroscience, 2006, Volume: 137, Issue:3 Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Dynorphins; Enkephalins; Gene Expression Regulation; GluK2 Kainate Receptor; In Situ Hybridization; Kainic Acid; Male; Mice; Mice, Transgenic; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glucocorticoid; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance P; Synaptic Transmission	2006
Motor-skill learning-associated gene regulation in the striatum: effects of cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:12 Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Dynorphins; Enkephalins; Gene Expression Regulation; Learning; Male; Motor Activity; Motor Skills; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substance P; Up-Regulation	2006
Paradoxical effects of prodynorphin gene deletion on basal and cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens. The European journal of neuroscience, 2006, Volume: 23, Issue:1 Topics: Analgesics; Animals; Area Under Curve; Behavior, Animal; Benzeneacetamides; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Electrochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Motor Activity; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pyrrolidines	2006
Regulation of psychostimulant-induced preprodynorphin, c-fos and zif/268 messenger RNA expression in the rat dorsal striatum by mu opioid receptor blockade. European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2 Topics: Animals; Central Nervous System Stimulants; Cinnamates; Cocaine; Corpus Striatum; Dynorphins; Early Growth Response Protein 1; Gene Expression; In Situ Hybridization; Male; Methamphetamine; Morphine Derivatives; Narcotic Antagonists; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; RNA, Messenger; Time Factors	2006
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. Neuroscience, 2007, Jan-05, Volume: 144, Issue:1 Topics: Animals; Benzeneacetamides; Blotting, Northern; Central Nervous System; Cocaine; Dynorphins; Enkephalins; Fluoxetine; Hippocampus; Hypothalamus; Male; Neostriatum; Protein Precursors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA Probes; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin	2007
Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration. Journal of neurochemistry, 2007, Volume: 102, Issue:6 Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cocaine; Cocaine-Related Disorders; Corticosterone; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Administration Schedule; Dynorphins; Guanosine 5'-O-(3-Thiotriphosphate); Hypothalamo-Hypophyseal System; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pituitary-Adrenal System; Protein Precursors; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, kappa; Receptors, Opioid, mu	2007
Effects of cocaine place conditioning, chronic escalating-dose "binge" pattern cocaine administration and acute withdrawal on orexin/hypocretin and preprodynorphin gene expressions in lateral hypothalamus of Fischer and Sprague-Dawley rats. Neuroscience, 2008, Jun-02, Volume: 153, Issue:4 Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Dynorphins; Gene Expression Regulation; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Naloxone; Narcotic Antagonists; Neuropeptides; Orexins; Protein Precursors; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome; Time Factors	2008
Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:4 Topics: Acoustic Stimulation; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Conditioning, Operant; Dopamine Uptake Inhibitors; Drug Administration Schedule; Drug Delivery Systems; Dynorphins; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Locomotion; Male; Methadone; Neuropeptides; Orexins; Photic Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; RNA, Messenger	2009
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides. Neuropharmacology, 2010, Volume: 58, Issue:1 Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors	2010
Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:9 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Association Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Dynorphins; Exploratory Behavior; Male; Mental Recall; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reward; Stress, Psychological; Swimming	2010
Exposure to cocaine alters dynorphin-mediated regulation of excitatory synaptic transmission in nucleus accumbens neurons. Biological psychiatry, 2011, Feb-01, Volume: 69, Issue:3 Topics: Animals; Cocaine; Drug Interactions; Dynorphins; Excitatory Postsynaptic Potentials; Male; Naltrexone; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Synaptic Transmission	2011
Methylphenidate alters basal ganglia neurotensin systems through dopaminergic mechanisms: a comparison with cocaine treatment. Journal of neurochemistry, 2011, Volume: 117, Issue:3 Topics: Animals; Basal Ganglia; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Male; Methylphenidate; Neurotensin; Radioimmunoassay; Rats; Rats, Sprague-Dawley	2011
Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2 Topics: Analgesics, Opioid; Animals; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Delivery Systems; Dynorphins; Gene Expression; Locomotion; Male; Methadone; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; RNA, Messenger; Stereotyped Behavior	2012
Cocaine-induced dendritic remodeling occurs in both D1 and D2 dopamine receptor-expressing neurons in the nucleus accumbens. Neuroscience letters, 2012, May-31, Volume: 517, Issue:2 Topics: Animals; Cocaine; Coloring Agents; Dendrites; Dendritic Spines; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dynorphins; Female; Immunohistochemistry; Lysine; Male; Mice; Nucleus Accumbens; Receptors, Dopamine D2; Receptors, Dopamine D3; Signal Transduction	2012
Chronic escalating cocaine exposure, abstinence/withdrawal, and chronic re-exposure: effects on striatal dopamine and opioid systems in C57BL/6J mice. Neuropharmacology, 2013, Volume: 67 Topics: Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dynorphins; Male; Mice; Mice, Inbred C57BL; Motor Activity; Protein Precursors; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance Withdrawal Syndrome; Time Factors	2013
Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Dec-05, Volume: 32, Issue:49 Topics: Animals; Avoidance Learning; Brain; Cocaine; Corpus Striatum; Dopamine; Dynorphins; G-Protein-Coupled Receptor Kinase 3; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microinjections; Naltrexone; Narcotic Antagonists; Nicotine; Nucleus Accumbens; p38 Mitogen-Activated Protein Kinases; Raphe Nuclei; Receptors, Opioid, kappa; Reward; Serotonin; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Stress, Psychological; Substance Withdrawal Syndrome; Synaptosomes	2012
Enhanced nicotine-seeking behavior following pre-exposure to repeated cocaine is accompanied by changes in BDNF in the nucleus accumbens of rats. Pharmacology, biochemistry, and behavior, 2013, Volume: 104 Topics: Animals; Brain-Derived Neurotrophic Factor; Cocaine; Dynorphins; Gene Expression; Male; Motor Activity; Neuropeptide Y; Nicotine; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, trkB; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid, mu; Risk Factors; Self Administration; Tobacco Use Disorder	2013
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry, 2014, Mar-03, Volume: 49 Topics: Animals; Cocaine; Corpus Striatum; Dynorphins; Enkephalins; Epigenesis, Genetic; Gene Expression Regulation; Histones; Male; Nociceptin; Nociceptin Receptor; Nucleus Accumbens; Opioid Peptides; Protein Precursors; Rats; Receptors, Opioid; Receptors, Opioid, kappa	2014
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area. Proceedings of the National Academy of Sciences of the United States of America, 2014, Apr-22, Volume: 111, Issue:16 Topics: Animals; Cocaine; Dopaminergic Neurons; Dynorphins; Hypothalamus; Impulsive Behavior; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuropeptides; Neurotransmitter Agents; Orexin Receptors; Orexins; Reward; Self Administration; Synaptic Transmission; Ventral Tegmental Area	2014
Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:5 Topics: Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Drug Interactions; Dynorphins; Excitatory Postsynaptic Potentials; Extinction, Psychological; Male; Microinjections; Miniature Postsynaptic Potentials; Naltrexone; Orexins; Paraventricular Hypothalamic Nucleus; Rats; Reward; Self Administration	2018
Kappa-opioid receptors, dynorphin, and cocaine addiction: a positron emission tomography study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:10 Topics: Adult; Brain; Carbon Radioisotopes; Case-Control Studies; Choice Behavior; Cocaine; Cocaine Smoking; Cocaine-Related Disorders; Dynorphins; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neostriatum; Piperazines; Positron-Emission Tomography; Pyrrolidines; Receptors, Opioid, kappa; Stress, Psychological	2019
Cocaine Dysregulates Dynorphin Modulation of Inhibitory Neurotransmission in the Ventral Pallidum in a Cell-Type-Specific Manner. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020, 02-05, Volume: 40, Issue:6 Topics: Animals; Basal Forebrain; Cocaine; Drug-Seeking Behavior; Dynorphins; Female; Male; Mice; Mice, Inbred C57BL; Neurons; Reward; Substance Withdrawal Syndrome; Synaptic Transmission	2020