cocaine has been researched along with dizocilpine maleate in 136 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.21) | 18.7374 |
| 1990's | 69 (50.74) | 18.2507 |
| 2000's | 38 (27.94) | 29.6817 |
| 2010's | 22 (16.18) | 24.3611 |
| 2020's | 4 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Acuff, CG; Farley, JM; Ho, IK; Hoskins, B; Oden, G; Rockhold, RW; Surrett, RS; Zhang, T | 1 |
| De Montis, MG; Devoto, P; Gambarana, C; Giorgi, G; Meloni, D; Tagliamonte, A | 1 |
| Bush, L; Gibb, JW; Hanson, GR; Johnson, M; Merchant, K; Singh, N | 1 |
| Itzhak, Y; Stein, I | 1 |
| Gessa, GL; Hmaidan, Y; Rossetti, ZL | 1 |
| Kuribara, H; Tadokoro, S; Uchihashi, Y | 1 |
| Bush, LG; Gibb, JW; Hanson, GR; Johnson, M; Midgley, L | 1 |
| Acuff, CG; Ho, IK; Hoskins, B; Rockhold, RW; Surrett, RS; Zhang, T | 1 |
| Calder, LD; Karler, R | 1 |
| Albertson, TE; Derlet, RW; Tseng, CC | 1 |
| Rockhold, RW | 1 |
| Bush, LG; Gibb, JW; Hanson, GR; Johnson, M | 1 |
| Cory-Slechta, DA; Widzowski, DV | 1 |
| Andrew, M; Farley, JM; Ho, IK; Oden, G; Rockhold, RW | 1 |
| Tortella, FC; Witkin, JM | 1 |
| Balster, RL; Beardsley, PM; Hayes, BA | 1 |
| Albertson, TE; Derlet, RW; Rice, P | 1 |
| Calder, LD; Chaudhry, IA; Karler, R; Turkanis, SA | 1 |
| Colpaert, FC; Kamenka, JM; Koek, W; Woods, JH | 1 |
| Palmer, RK; Winger, G; Woods, JH | 1 |
| Belanger, SA; Haracz, JL; MacDonall, JS; Sircar, R | 1 |
| Itzhak, Y | 2 |
| Cervo, L; Samanin, R | 2 |
| Bradberry, CW; Pap, A | 1 |
| Christensen, JR; Flory, GS; Miller, DW; Rebec, GV; White, IM | 1 |
| Carey, RJ; Damianopoulos, EN | 1 |
| Marley, RJ; Saito, T; Shimosato, K | 1 |
| Carey, RJ; Dai, H; Huston, JP; Krost, M | 1 |
| Gibb, JW; Hanson, GR; Johnson, M; Merchant, K; Singh, N | 1 |
| Bedingfield, JB; Calder, LD; Karler, R; Thai, LH | 1 |
| Bankson, MG; Gibbs, S; Higley, D; Horger, BA; House, DT; McNamara, C; Schenk, S; Valadez, A | 1 |
| Pert, A; Zocchi, A | 1 |
| Dahlin, SL; White, FJ; Wolf, ME; Xue, CJ | 1 |
| Seidleck, BK; Thurkauf, A; Witkin, JM | 1 |
| Jeziorski, M; Wolf, ME | 1 |
| Alesdatter, JE; Kalivas, PW | 1 |
| Fontana, DJ; Pert, A; Post, RM | 1 |
| Bennett, JG; Byrne, M; Rockhold, RW; Sprabery, S | 1 |
| Hageman, GR; Simor, T | 1 |
| Bozarth, MA; Pudiak, CM | 1 |
| Rivier, C; Torres, G | 1 |
| Hashimoto, K; Minabe, Y; Narita, N; Tamura, A; Tomitaka, S | 1 |
| Asami, T; Ida, I; Kuribara, H | 1 |
| Jang, CG; Kim, HS; Oh, S; Park, WK | 1 |
| Baker, I; Masserano, JM; Natsukari, N; Wyatt, RJ | 1 |
| French, E; Ranaldi, R; Roberts, DC | 1 |
| DiPirro, JM; Horowitz, JM; Kristal, MB; Torres, G | 1 |
| Bauco, P; Ranaldi, R; Wise, RA | 1 |
| Carter, RB; Gasior, M; Goldberg, SR; Witkin, JM | 1 |
| Pert, A | 1 |
| Kalivas, PW; Meil, WM; Pierce, RC | 1 |
| Gan, Q; Knuepfer, MM | 1 |
| Edwards, MA; Kantak, KM; O'Connor, TP | 1 |
| Binnekade, R; De Vries, TJ; Mulder, AH; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Karoum, F; Masserano, J; Wyatt, RJ | 1 |
| Inoue, O; Iwamoto, B; Matoba, Y; Nakano, T; Nishimura, T; Nishiura, M; Takatoku, K | 1 |
| Gambarana, C; Ghiglieri, O; Montis, MG; Tagliamonte, A | 1 |
| Schmidt, WJ; Tzschentke, TM | 1 |
| Harvey, DC; Huang, SC; Lacan, G; Melega, WP; Phelps, ME | 1 |
| Itzhak, Y; Martin, JL | 1 |
| Bhargava, HN; Kumar, S | 1 |
| De Montis, MG; Gambarana, C; Tagliamonte, A | 1 |
| Heron-Maxwell, CL; O'Neill, MF; Shaw, G | 1 |
| Carey, R; Damianopoulos, E; DePalma, G | 1 |
| O'Neill, MF; Sanger, GJ | 1 |
| Benuck, M; Hashim, A; Lajtha, A; Sershen, H; Sziraki, I | 1 |
| Bäckström, P; Hyytiä, P; Liljequist, S | 1 |
| O'Neill, MF; Shaw, G | 1 |
| Cornish, JL; Duffy, P; Kalivas, PW | 1 |
| Bardo, MT; Bevins, RA | 1 |
| Forster, MJ; Lal, H; Uzbay, IT; Wallis, CJ | 1 |
| Castellano, C; Cestari, V; Ciamei, A | 1 |
| Balster, RL; Beardsley, PM; Bespalov, AY; Dravolina, OA; Zvartau, EE | 1 |
| Schmidt, WJ; Tzchentke, TM | 1 |
| Parada, A; Soares-da-Silva, P | 1 |
| Li, Y; White, FJ; Wolf, ME | 2 |
| Glick, SD; Herrick-Davis, K; Maisonneuve, IM; Szumlinski, KK; Teitler, M | 1 |
| Breitinger, HG; Coombs, SE; Gameiro, AM; Grewer, C; Hess, GP; Ippolito, JE; Jayaraman, V; Lee, SM; Niu, L; Srivastava, S; Ulrich, H | 1 |
| Hashim, A; Lajtha, A; Sershen, H | 1 |
| Baek, D; Bergstrom, DA; Freeman, LE; Ruskin, DN; Walters, JR | 1 |
| Stavale, JN; Villares, JC | 1 |
| Baunez, C; Bernardi, G; Borrelli, E; Calabresi, P; Centonze, D; Picconi, B; Pisani, A | 1 |
| De Montis, MG; Gambarana, C; Mangiavacchi, S; Masi, F; Scheggi, S; Tagliamonte, A | 1 |
| Hashim, A; Lajtha, A; Sershen, H; Sziráki, I | 1 |
| Inoue, O; Kagawa, S; Nakano, T; Nishimura, T | 1 |
| Atack, JR; Bromidge, FA; Dawson, GR; Newman, RJ; O'Meara, GF; Reynolds, DS; Rosahl, TW; Whiting, PJ | 1 |
| Carroll, FI; Chen, Y; Gameiro, AM; Ganem, B; Hess, GP; Nye, JA; Schoenfeld, RC; Sit, B; Ulrich, H | 1 |
| Forman, LJ | 1 |
| Festa, ED; Inturrisi, CE; Jenab, S; Quinones-Jenab, V; Russo, SJ; Wu, HB | 1 |
| Hess, GP; Krivoshein, AV | 1 |
| Bagetta, G; Corasaniti, MT; De Alba, J; Del Duca, C; Knowles, RG; Morrone, LA; Nappi, G; Piccirilli, S; Rombolà, L | 1 |
| Fields, HL; Hjelmstad, GO; Kim, JA; Pollak, KA | 1 |
| Banerjee, A; Chen, Y; Hess, GP | 1 |
| Adewale, AS; Lee, B; Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Cui, Y; Hess, GP; Ulrich, H | 1 |
| Allen, RM; Carelli, RM; Dykstra, LA; Everett, CV; Suchey, TL | 1 |
| Storvik, M; Tiikkainen, P; van Iersel, M; Wong, G | 1 |
| Festa, ED; Hazim, R; Jenab, S; Nazarian, A; Quinones-Jenab, V; Russo, SJ; Sun, WL; Wu, HB | 1 |
| Atalla, A; Grönig, M; Kuschinsky, K | 1 |
| Ahn, SM; Choe, ES; Kim, SW | 1 |
| Gao, F; Jiao, H; Lou, D; Xu, M; Zhang, J; Zhang, L | 1 |
| Guimarães, FS; Leite, JV; Moreira, FA | 1 |
| Knuepfer, MM; Reilly, NS; Schwartz, JA | 1 |
| Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Brown, TE; Lee, BR; Sorg, BA | 1 |
| Gass, JT; Olive, MF | 1 |
| Jenab, S; Quinones-Jenab, V; Sun, WL; Zhou, L | 1 |
| Aubier, B; Bertran-Gonzalez, J; Girault, JA; Greengard, P; Hervé, D; Valjent, E | 1 |
| Hess, GP; Pagán, OR; Sivaprakasam, K | 1 |
| Der-Ghazarian, T; Herbert, MS; McDougall, SA; Palmer, AG | 1 |
| Budziszewska, B; Gasior, M; Kaminski, RM; Lasoń, W; Núñez-Taltavull, JF; Shippenberg, TS; Witkin, JM; Zapata, A | 1 |
| Fletcher, PJ; Higgins, GA; Noble, K; Rizos, Z | 1 |
| Kaneko, S; Kitaichi, M; Nagayasu, K; Nakagawa, T; Shirakawa, H; Suzuki, Y | 1 |
| Castagné, V; Quinn, L; Virley, D; Wolinsky, T | 1 |
| Alaghband, Y; Marshall, JF | 1 |
| Davis-MacNevin, PL; Dekraker, J; Holahan, MR; LaDouceur, L | 1 |
| Allen, RM | 1 |
| Bernardi, RE; Halbout, B; Hansson, AC; Spanagel, R | 1 |
| Hillhouse, TM; Negus, SS; Porter, JH | 1 |
| Alaghband, Y; Azarnia, S; Guzowski, JF; Khalaj, AJ; Marshall, JF; O'Dell, SJ | 1 |
| Itzhak, Y; Liddie, S | 1 |
| Allen, RM; Bergkamp, D; Hackley, A; Jaskunas, J; Mandt, BH; Shickedanz, A | 1 |
| Lee, P; Sternson, SM; Yang, Y | 1 |
| Chen, L; Ge, S; Li, N; Li, Y; Wang, J; Wang, X; Wu, H; Zhang, S | 1 |
| Cancela, LM; De Giovanni, LN; Guzman, AS; Virgolini, MB | 1 |
| Balouch, B; Jenab, S; Klambatsen, A; Nygard, SK; Quinones-Jenab, V | 1 |
| Dakmak, Z; Galaj, E; Ranaldi, R; Seepersad, N | 1 |
| Barlow, RL; Dalley, JW; Pekcec, A | 1 |
| Aug, I; Bregin, A; Innos, J; Mazitov, T; Philips, MA; Vasar, E | 1 |
| Balu, DT; Coyle, JT; Takagi, S | 1 |
| Andrade, YCP; Batista, LA; Del Bel, EA; Fanelli, C; Issy, AC; Liégeois, JF; Minaldi, E; Moreira, FA; Rodrigues, LCM; Ropke, J; Viana, TG | 1 |
| Hess, GP; Sivaprakasam, K | 1 |
| Broderick, MR; Horchar, MJ; Kappesser, JL; Wright, MR; Yates, JR | 1 |
2 review(s) available for cocaine and dizocilpine maleate
| Article | Year |
|---|---|
Responses of limbic and extrapyramidal neurotensin systems to stimulants of abuse. Involvement of dopaminergic mechanisms.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dopamine; Dopamine Agents; Illicit Drugs; Limbic System; Methamphetamine; Neurotensin; Phencyclidine; Pyramidal Tracts; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1992 |
Neurobiological substrates underlying conditioned effects of cocaine.
Topics: Animals; Brain; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Humans; Motor Activity; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance-Related Disorders | 1998 |
1 trial(s) available for cocaine and dizocilpine maleate
| Article | Year |
|---|---|
One-trial cocaine-induced behavioral sensitization in preweanling rats: role of contextual stimuli.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Female; Locomotion; Male; Methylphenidate; Motor Activity; Neuroprotective Agents; Physical Stimulation; Rats; Rats, Sprague-Dawley | 2010 |
133 other study(ies) available for cocaine and dizocilpine maleate
| Article | Year |
|---|---|
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.
Topics: Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Neurotoxins; Piperazines; Receptors, Neurotransmitter; Seizures | 1992 |
NMDA receptor inhibition prevents tolerance to cocaine.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dopamine Agents; Drug Tolerance; Ergolines; Male; Motor Activity; Quinpirole; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1992 |
Sensitization to the toxic effects of cocaine in mice is associated with the regulation of N-methyl-D-aspartate receptors in the cortex.
Topics: Animals; Body Weight; Cerebral Cortex; Cocaine; Dizocilpine Maleate; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures | 1992 |
Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Ethanol; Male; Morphine; Naloxone; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1992 |
Assessment of the ambulation-increasing effect of ketamine by coadministration with central-acting drugs in mice.
Topics: alpha-Methyltyrosine; Animals; Caffeine; Central Nervous System Agents; Central Nervous System Depressants; Ceruletide; Cocaine; Dizocilpine Maleate; Drug Synergism; Ketamine; Male; Methamphetamine; Methyltyrosines; Mice; Morphine; Motor Activity; Neurotransmitter Uptake Inhibitors; Nimodipine; Piperazines; Scopolamine | 1992 |
MK-801 blocks the changes in neurotensin concentrations induced by methamphetamine, 3,4-methylenedioxymethamphetamine, cocaine, and GBR 12909.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Cocaine; Dizocilpine Maleate; Male; Methamphetamine; Neurotensin; Piperazines; Rats; Rats, Sprague-Dawley | 1992 |
Antagonism of the toxicity of cocaine by MK-801: differential effects in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Animals; Blood Pressure; Body Temperature; Body Weight; Cocaine; Dizocilpine Maleate; Heart Rate; Infusions, Intravenous; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Seizures; Species Specificity | 1992 |
Excitatory amino acids and the actions of cocaine.
Topics: Animals; Caffeine; Cocaine; Dextromethorphan; Dizocilpine Maleate; Haloperidol; Male; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Pipecolic Acids; Quinoxalines; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism; Stereotyped Behavior | 1992 |
Cocaine-induced respiratory depression and seizures are synergistic mechanisms of cocaine-induced death in rats.
Topics: Animals; Cocaine; Death; Dizocilpine Maleate; Drug Synergism; Electrocardiography; Electroencephalography; Male; Rats; Rats, Inbred Strains; Respiration, Artificial; Respiratory Insufficiency; Seizures; Sodium Chloride; Tracheostomy; Valproic Acid | 1992 |
Excitatory amino acid receptor antagonists: potential implications for cardiovascular therapy and cocaine intoxication.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Cocaine; Dizocilpine Maleate; Heart Rate; Humans; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1991 |
Role of N-methyl-D-aspartate (NMDA) receptors in the response of extrapyramidal neurotensin and dynorphin A systems to cocaine and GBR 12909.
Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dynorphins; Male; Neurotensin; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Substantia Nigra | 1991 |
Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Cocaine; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Dopamine Agents; Drug Synergism; Ergolines; Generalization, Psychological; Haloperidol; Lead; Male; Morphine; N-Methylaspartate; Pentobarbital; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Glutamate receptor antagonists block cocaine-induced convulsions and death.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Cocaine; Death; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Kynurenic Acid; Male; Mice; Mice, Inbred ICR; Piperazines; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Time Factors | 1991 |
Modulators of N-methyl-D-aspartate protect against diazepam- or phenobarbital-resistant cocaine convulsions.
Topics: Amino Acids; Animals; Anticonvulsants; Cocaine; Diazepam; Dizocilpine Maleate; Male; Mice; Phencyclidine; Phenobarbital; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Time Factors | 1991 |
The self-administration of MK-801 can depend upon drug-reinforcement history, and its discriminative stimulus properties are phencyclidine-like in rhesus monkeys.
Topics: Animals; Anticonvulsants; Cocaine; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Infusions, Intravenous; Macaca mulatta; Male; Phencyclidine; Reinforcement, Psychology; Self Administration | 1990 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Haloperidol; Lethal Dose 50; Male; Methamphetamine; N-Methylaspartate; Propranolol; Rats; Rats, Inbred Strains; Seizures | 1990 |
Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801.
Topics: Amphetamine; Animals; Anticonvulsants; Cocaine; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Haloperidol; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1989 |
The phencyclidine (PCP) analog N-[1-(2-benzo(B)thiophenyl) cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801.
Topics: Animals; Behavior, Animal; Cocaine; Columbidae; Dextroamphetamine; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Haloperidol; Ketamine; Methylphenidate; Mice; Phencyclidine; Rats; Seizures; Structure-Activity Relationship | 1989 |
Drug-reinforced responding: rapid determination of dose-response functions.
Topics: Animals; Anticonvulsants; Appetitive Behavior; Arousal; Cocaine; Conditioning, Operant; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Ketamine; Macaca mulatta; Male; Motivation; Nomifensine; Phencyclidine; Self Administration | 1989 |
Antagonist of N-methyl-D-aspartate receptors partially prevent the development of cocaine sensitization.
Topics: Animals; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Male; Motor Activity; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Nitric oxide (NO) synthase inhibitors abolish cocaine-induced toxicity in mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cocaine; Dizocilpine Maleate; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, Phencyclidine; Seizures | 1993 |
Effects of dopaminergic and glutamatergic receptor antagonists on the acquisition and expression of cocaine conditioning place preference.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulpiride | 1995 |
Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Drug Interactions; Excitatory Amino Acids; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1995 |
Amphetamine, cocaine, and dizocilpine enhance performance on a lever-release, conditioned avoidance response task in rats.
Topics: Amphetamine; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1995 |
Evidence for N-methyl-D-aspartate receptor mediation of cocaine induced corticosterone release and cocaine conditioned stimulant effects.
Topics: Animals; Arousal; Association Learning; Brain; Cocaine; Conditioning, Classical; Corticosterone; Dizocilpine Maleate; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Social Environment | 1995 |
Differential effects of NMDA receptor and dopamine receptor antagonists on cocaine toxicities.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride; Time Factors | 1995 |
The NMDA receptor and cocaine: evidence that MK-801 can induce behavioral sensitization effects.
Topics: Animals; Behavior, Animal; Cocaine; Dizocilpine Maleate; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical | 1995 |
The role of NMDA receptor systems in neuropeptide responses to stimulants of abuse.
Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dynorphins; Methamphetamine; N-Methylaspartate; Neuropeptides; Neurotensin; Nucleus Accumbens; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
A dopaminergic-glutamatergic basis for the action of amphetamine and cocaine.
Topics: Amphetamine; Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Male; Mice; Piperazines; Quinoxalines; Receptors, Dopamine; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Sulpiride | 1994 |
Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors.
Topics: Amphetamine; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Self Administration | 1993 |
Alterations in striatal acetylcholine overflow by cocaine, morphine, and MK-801: relationship to locomotor output.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Space; Male; Microdialysis; Morphine; Motor Activity; Neostriatum; Rats; Rats, Sprague-Dawley | 1994 |
MK-801 does not prevent acute stimulatory effects of amphetamine or cocaine on locomotor activity or extracellular dopamine levels in rat nucleus accumbens.
Topics: Amphetamine; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Extracellular Space; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Evaluation of ADCI against convulsant and locomotor stimulant effects of cocaine: comparison with the structural analogs dizocilpine and carbamazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Seizures; Substance-Related Disorders | 1994 |
Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization.
Topics: Amphetamine; Analysis of Variance; Animals; Cocaine; Dizocilpine Maleate; Drug Interactions; Male; Morphine; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley | 1993 |
Involvement of N-methyl-D-aspartate receptor stimulation in the ventral tegmental area and amygdala in behavioral sensitization to cocaine.
Topics: Amygdala; Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Microinjections; Motor Activity; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 1993 |
Conditioned increases in mesolimbic dopamine overflow by stimuli associated with cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dizocilpine Maleate; Dopamine; Homovanillic Acid; Male; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Time Factors | 1993 |
Urethane anesthesia reverses the protective effect of noncompetitive NMDA receptor antagonists against cocaine intoxication.
Topics: Anesthesia; Animals; Blood Pressure; Body Temperature; Cocaine; Consciousness; Dextrorphan; Dizocilpine Maleate; Drug Interactions; Heart Rate; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiration Disorders; Seizures; Urethane | 1994 |
Attenuation of the cardiac effects of cocaine by dizocilpine.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cocaine; Dizocilpine Maleate; Dogs; Efferent Pathways; Female; Heart; Heart Conduction System; Heart Ventricles; Male | 1993 |
L-NAME and MK-801 attenuate sensitization to the locomotor-stimulating effect of cocaine.
Topics: Animals; Arginine; Cocaine; Dizocilpine Maleate; Drug Interactions; Drug Synergism; Locomotion; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Stimulation, Chemical; Time Factors | 1993 |
Cocaine-induced expression of striatal c-fos in the rat is inhibited by NMDA receptor antagonists.
Topics: Animals; Cocaine; Corpus Striatum; Dizocilpine Maleate; Gene Expression; Genes, fos; Ketamine; Male; Organ Specificity; Piperazines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
Amantadine induces c-fos in rat striatum: reversal with dopamine D1 and NMDA receptor antagonists.
Topics: Amantadine; Animals; Cocaine; Dizocilpine Maleate; Dopamine Agents; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; Methamphetamine; Neostriatum; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 1995 |
Inhibition of cocaine sensitization by MK-801, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: evaluation by ambulatory activity in mice.
Topics: Analysis of Variance; Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, N-Methyl-D-Aspartate; Time Factors | 1995 |
Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice.
Topics: Animals; Apomorphine; Choice Behavior; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Locomotion; Male; Mice; Mice, Inbred ICR; Narcotic Antagonists; Receptors, Dopamine | 1996 |
Effects of dopaminergic and glutamatergic receptor antagonists on the establishment and expression of conditioned locomotion to cocaine in rats.
Topics: Analysis of Variance; Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Locomotion; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recurrence; Substance-Related Disorders; Sulpiride | 1996 |
Chronic cocaine administration increases tyrosine hydroxylase activity in the ventral tegmental area through glutaminergic- and dopaminergic D2-receptor mechanisms.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Glutamate; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 1996 |
Systemic pretreatment with MK-801 (dizocilpine) increases breaking points for self-administration of cocaine on a progressive-ratio schedule in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Narcotics; Rats; Rats, Wistar; Self Administration | 1996 |
Dopaminergic and glutamatergic mechanisms mediate the induction of FOS-like protein by cocaethylene.
Topics: Analgesics; Animals; Benzazepines; Brain; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Kinetics; Neurons; Proto-Oncogene Proteins c-fos; Pyrrolidines; Rats; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1997 |
Synergistic effects of cocaine and dizocilpine (MK-801) on brain stimulation reward.
Topics: Animals; Brain; Cocaine; Dizocilpine Maleate; Drug Synergism; Male; Rats; Reward; Self Stimulation | 1997 |
Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam.
Topics: Animals; Anticonvulsants; Cocaine; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Neuroprotective Agents; Phenobarbital; Steroids | 1997 |
The NMDA antagonist, dizocilpine, enhances cocaine reinforcement without influencing mesoaccumbens dopamine transmission.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Male; Microdialysis; Nucleus Accumbens; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 1997 |
Effects of proposed treatments for cocaine addiction on hemodynamic responsiveness to cocaine in conscious rats.
Topics: Animals; Bromocriptine; Buprenorphine; Cocaine; Desipramine; Diazepam; Dizocilpine Maleate; Hemodynamics; Male; Piperazines; Rats; Rats, Sprague-Dawley; Substance-Related Disorders | 1997 |
Modulation of the discriminative stimulus and rate-altering effects of cocaine by competitive and noncompetitive N-methyl-D-aspartate antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Binding, Competitive; Cocaine; Discrimination Learning; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Magnesium Chloride; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule | 1998 |
MK-801 reinstates drug-seeking behaviour in cocaine-trained rats.
Topics: Analysis of Variance; Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration; Substance-Related Disorders | 1998 |
Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine.
Topics: Aged; Animals; Antipsychotic Agents; Brain; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine; Humans; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Time Factors; Vitamin E | 1998 |
Enhancement of in vivo binding of [123I]beta-CIT by MK-801 in rat brain.
Topics: Animals; Brain; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Iodine Radioisotopes; Male; Rats; Rats, Wistar | 1998 |
Under continuous dizocilpine infusion an N-methyl-D-aspartate receptor independent form of cocaine sensitization develops in rats.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1998 |
Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm.
Topics: Amphetamine; Analgesics, Opioid; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Morphine; Motor Activity; Prefrontal Cortex; Psychomotor Performance; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reward | 1998 |
Dizocilpine and reduced body temperature do not prevent methamphetamine-induced neurotoxicity in the vervet monkey: [11C]WIN 35,428 - positron emission tomography studies.
Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Chlorocebus aethiops; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hypothermia; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Nerve Tissue Proteins; Neuroprotective Agents; Tomography, Emission-Computed | 1998 |
Effects of cocaine, nicotine, dizocipline and alcohol on mice locomotor activity: cocaine-alcohol cross-sensitization involves upregulation of striatal dopamine transporter binding sites.
Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Agonists; Ganglionic Stimulants; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Nicotine; Up-Regulation | 1999 |
Sensitization to the locomotor stimulant effect of cocaine modifies the binding of [3H]MK-801 to brain regions and spinal cord of the mouse.
Topics: Animals; Brain; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance Withdrawal Syndrome; Tritium | 1999 |
NMDA receptor-dependent and -independent behavioural sensitization.
Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Humans; Learning; Rats; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior | 1999 |
5-HT2 receptor antagonism reduces hyperactivity induced by amphetamine, cocaine, and MK-801 but not D1 agonist C-APB.
Topics: Aminopyridines; Amphetamine; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Female; Fluorobenzenes; Indoles; Mice; Motor Activity; Piperidines; Ritanserin; Serotonin Antagonists | 1999 |
Issues in the pharmacological modification of cocaine conditioning: evidence that the stimulus properties of drugs can interact with contextual cues to activate or inactivate cocaine conditioned stimuli.
Topics: Animals; Brain; Buspirone; Cocaine; Conditioning, Operant; Cues; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Grooming; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1999 |
A single pretreatment with MK-801 or cocaine enhances their locomotor stimulant effects in rats.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Motor Activity; Rats; Rats, Inbred Strains | 1999 |
Differences in receptor system participation between nicotine- and cocaine-induced dopamine overflow in nucleus accumbens.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Male; Microdialysis; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Nicotinic | 1999 |
Site-specific NMDA receptor antagonists produce differential effects on cocaine self-administration in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Self Administration | 1999 |
Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice.
Topics: Amphetamine; Analysis of Variance; Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Locomotion; Mice; Receptors, Dopamine D1 | 1999 |
A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Benzazepines; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamates; Glutamic Acid; Male; Nucleus Accumbens; Procaine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recurrence; Self Administration; Synaptic Transmission | 1999 |
Conditioned increase in place preference by access to novel objects: antagonism by MK-801.
Topics: Animals; Appetite; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Environment; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward; Substance-Related Disorders | 1999 |
Effects of NMDA receptor blockers on cocaine-stimulated locomotor activity in mice.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate | 2000 |
Strain-dependent interactions between MK-801 and cocaine on retention of C57BL/6 and DBA/2 mice tested in a one-trial inhibitory avoidance task: involvement of dopaminergic mechanisms.
Topics: Animals; Avoidance Learning; Benzazepines; Cocaine; Conditioning, Classical; Dizocilpine Maleate; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Inhibition, Psychological; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Sulpiride | 2000 |
Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Memantine; Motor Activity; Piperazines; Piperidines; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Effects of the non-competitive NMDA-receptor antagonist memantine on morphine- and cocaine-induced potentiation of lateral hypothalamic brain stimulation reward.
Topics: Analgesics, Opioid; Animals; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; Memantine; Morphine; Rats; Rats, Long-Evans; Reward | 2000 |
The dopamine antagonist sch 23390 reverses dizocilpine-induced blockade of cocaine sensitization.
Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Dopamine D1 | 2000 |
Pharmacological reversal of behavioral and cellular indices of cocaine sensitization in the rat.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Self Administration | 2000 |
Behavioural sensitization to cocaine is dissociated from changes in striatal NMDA receptor levels.
Topics: Animals; Behavior, Animal; Cocaine; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retreatment; Stereotyped Behavior; Time Factors | 2000 |
Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801.
Topics: Animals; Cell Line; Cocaine; Dizocilpine Maleate; Kinetics; Ligands; Receptors, Nicotinic | 2000 |
Serotonin-mediated striatal dopamine release involves the dopamine uptake site and the serotonin receptor.
Topics: Animals; Bicuculline; Cocaine; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Ketanserin; Male; Methiothepin; Mice; Mice, Inbred C57BL; Oxymetazoline; Piperazines; Quinoxalines; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
The expression of cocaine sensitization is not prevented by MK-801 or ibotenic acid lesions of the medial prefrontal cortex.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Ibotenic Acid; Male; Microinjections; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1999 |
Cocaine or selective block of dopamine transporters influences multisecond oscillations in firing rate in the globus pallidus.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Biological Clocks; Carrier Proteins; Cocaine; Desipramine; Dizocilpine Maleate; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Fluoxetine; Globus Pallidus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Periodicity; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors | 2001 |
Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia.
Topics: Adult; Aged; Aging; Autoradiography; Basal Ganglia; Caudate Nucleus; Cause of Death; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Nucleus Accumbens; Putamen; Radioligand Assay; Receptors, N-Methyl-D-Aspartate | 2001 |
Cocaine and amphetamine depress striatal GABAergic synaptic transmission through D2 dopamine receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amphetamine; Animals; Cocaine; Denervation; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Mice; Mice, Transgenic; Neostriatum; Neural Pathways; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Transmission | 2002 |
Dizocilpine infusion has a different effect in the development of morphine and cocaine sensitization: behavioral and neurochemical aspects.
Topics: Animals; Blotting, Western; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Excitatory Amino Acid Antagonists; Hippocampus; Limbic System; Male; Morphine; Morphine Dependence; Nucleus Accumbens; Pain Measurement; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2002 |
Receptors in the ventral tegmental area mediating nicotine-induced dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine; Kinetics; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Nicotinic; Ventral Tegmental Area | 2002 |
Effect of glutamatergic systems on in vivo binding of [(125)I]beta-CIT in the brain of a rat model of Parkinson's disease.
Topics: Animals; Autoradiography; Binding, Competitive; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Iodine Radioisotopes; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Serotonin; Sympatholytics | 2002 |
GABA(A) alpha 1 subunit knock-out mice do not show a hyperlocomotor response following amphetamine or cocaine treatment.
Topics: Amphetamine; Animals; Benzazepines; Binding, Competitive; Central Nervous System Stimulants; Cocaine; Diazepam; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Modulators; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Protein Subunits; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Spiperone | 2003 |
Reversing the action of noncompetitive inhibitors (MK-801 and cocaine) on a protein (nicotinic acetylcholine receptor)-mediated reaction.
Topics: Animals; Anticonvulsants; Cell Line; Cocaine; Dizocilpine Maleate; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Nicotinic Antagonists; Receptors, Nicotinic | 2003 |
The effect of cannabinoid receptor antagonism with SR141716A on antinociception induced by cocaine and the NMDA receptor antagonist, MK-801.
Topics: Anesthetics, Local; Animals; Cannabinoid Receptor Modulators; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Cannabinoid; Receptors, Drug; Receptors, N-Methyl-D-Aspartate; Rimonabant | 2003 |
MK-801 attenuates cocaine induction of c-fos and preprodynorphin mRNA levels in Fischer rats.
Topics: Anesthetics, Local; Animals; Cocaine; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Dynorphins; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; RNA, Messenger | 2003 |
Mechanism-based approach to the successful prevention of cocaine inhibition of the neuronal (alpha 3 beta 4) nicotinic acetylcholine receptor.
Topics: Animals; Binding Sites; Carbachol; Cell Line; Cocaine; Dizocilpine Maleate; Humans; Neural Inhibition; Neuromuscular Junction; Nicotinic Agonists; Nicotinic Antagonists; Protein Conformation; Protein Subunits; Rats; Receptors, Nicotinic | 2004 |
Inducible nitric oxide synthase is involved in the mechanisms of cocaine enhanced neuronal apoptosis induced by HIV-1 gp120 in the neocortex of rat.
Topics: Anesthetics, Local; Animals; Apoptosis; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; HIV Envelope Protein gp120; Male; Neocortex; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2004 |
A single cocaine exposure enhances both opioid reward and aversion through a ventral tegmental area-dependent mechanism.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Environment; Excitatory Amino Acid Antagonists; Male; Microinjections; Morphine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Ventral Tegmental Area | 2004 |
Mechanism-based discovery of small molecules that prevent noncompetitive inhibition by cocaine and MK-801 mediated by two different sites on the nicotinic acetylcholine receptor.
Topics: Animals; Binding, Competitive; Cell Line; Cocaine; Dizocilpine Maleate; Kinetics; Neural Inhibition; Nicotinic Antagonists; Patch-Clamp Techniques; Protein Binding; Receptors, Nicotinic | 2004 |
Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine.
Topics: Animals; Behavior, Animal; Cocaine; Discrimination Learning; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Male; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Saimiri; Self Administration | 2005 |
Selection of 2'-fluoro-modified RNA aptamers for alleviation of cocaine and MK-801 inhibition of the nicotinic acetylcholine receptor.
Topics: Animals; Binding Sites; Cells, Cultured; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electric Organ; Fluorine Compounds; Ligands; Nicotinic Antagonists; Receptors, Nicotinic; RNA; Torpedo | 2004 |
Effects of the competitive N-methyl-D-aspartate receptor antagonist, LY235959 [(-)-6-phosphonomethyl-deca-hydroisoquinoline-3-carboxylic acid], on responding for cocaine under both fixed and progressive ratio schedules of reinforcement.
Topics: Animals; Cocaine; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Isoquinolines; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Self Administration | 2005 |
Distinct gene expression profiles in adult rat brains after acute MK-801 and cocaine treatments.
Topics: Animals; Autoradiography; Brain Chemistry; Cocaine; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; DNA Probes; DNA, Complementary; Dopamine Uptake Inhibitors; Drug Synergism; Excitatory Amino Acid Antagonists; Gene Expression Profiling; In Situ Hybridization; Male; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Parietal Lobe; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA | 2006 |
Cocaine induction of ERK proteins in dorsal striatum of Fischer rats.
Topics: Animals; Benzazepines; Blotting, Western; Cocaine; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dizocilpine Maleate; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Induction; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Male; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred F344; Salicylamides | 2005 |
Effects of blockade of NMDA receptors and NO synthase on the expression of associative and non-associative sensitization to effects of cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dizocilpine Maleate; Enzyme Inhibitors; Injections, Intraperitoneal; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors; Vasoconstrictor Agents | 2006 |
Cocaine increases immunoglobulin heavy chain binding protein and caspase-12 expression in the rat dorsal striatum.
Topics: Animals; Benzazepines; Blotting, Western; Caspase 12; Cocaine; Corpus Striatum; Dizocilpine Maleate; Heat-Shock Proteins; Immunohistochemistry; Male; Molecular Chaperones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate | 2007 |
Dopamine D(1) and D(3) receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via NMDA receptor phosphorylation.
Topics: Animals; Blotting, Western; Brain Chemistry; Caudate Nucleus; Cocaine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Putamen; Receptors, Dopamine D1; Receptors, Dopamine D3; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2007 |
Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Aripiprazole; Catalepsy; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Partial Agonism; Excitatory Amino Acid Antagonists; Glutamine; Haloperidol; Hyperkinesis; Ketamine; Locomotion; Male; Mice; Motor Activity; Piperazines; Quinolones; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Time Factors | 2008 |
Angiotensin and NMDA receptors in the median preoptic nucleus mediate hemodynamic response patterns to stress.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Catheterization; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Agonists; Losartan; Microinjections; Muscimol; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Stress, Physiological; Time Factors | 2008 |
Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine.
Topics: Animals; Behavior, Animal; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Saimiri; Self Administration | 2008 |
Role of the NMDA receptor and nitric oxide in memory reconsolidation of cocaine-induced conditioned place preference in mice.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Dizocilpine Maleate; Indazoles; Male; Memory; Mice; Mice, Knockout; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2008 |
The NMDA antagonist MK-801 disrupts reconsolidation of a cocaine-associated memory for conditioned place preference but not for self-administration in rats.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Memory; Piperazines; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration | 2008 |
Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory.
Topics: Allosteric Site; Animals; Benzamides; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Memory; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2009 |
Cocaine effects on dopamine and NMDA receptors interactions in the striatum of Fischer rats.
Topics: Animals; Blotting, Western; Caudate Nucleus; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Immunoprecipitation; Male; N-Methylaspartate; Putamen; Rats; Rats, Inbred F344; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Time Factors; Tubulin | 2009 |
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
Topics: Analysis of Variance; Animals; Anisomycin; Cocaine; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Administration Routes; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Green Fluorescent Proteins; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Motor Activity; Narcotics; Point Mutation; Protein Synthesis Inhibitors; Raclopride; Receptors, Dopamine D1; Substance-Related Disorders; Threonine; Time Factors | 2010 |
Minimal RNA aptamer sequences that can inhibit or alleviate noncompetitive inhibition of the muscle-type nicotinic acetylcholine receptor.
Topics: Animals; Aptamers, Nucleotide; Base Sequence; Cell Line; Cocaine; Dizocilpine Maleate; Kinetics; Mice; Models, Theoretical; Molecular Sequence Data; Nucleic Acid Conformation; Receptors, Nicotinic | 2010 |
Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain.
Topics: Animals; Brain; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Kindling, Neurologic; Male; Mice; Microdialysis; Receptors, N-Methyl-D-Aspartate | 2011 |
Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT(2C) receptor stimulation and 5-HT(2A) receptor blockade.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethylamines; Excitatory Amino Acid Antagonists; Fluorobenzenes; Impulsive Behavior; Indoles; Male; Piperidines; Psychomotor Performance; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2011 |
Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures.
Topics: Animals; Cocaine; Coculture Techniques; Dizocilpine Maleate; Dopamine; Dopamine Uptake Inhibitors; Female; Immunohistochemistry; Limbic System; Male; Methamphetamine; Morphine; Neurons; Propidium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2011 |
Differential behavioral profiling of stimulant substances in the rat using the LABORAS™ system.
Topics: Animals; Automation; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Dextroamphetamine; Dizocilpine Maleate; Drinking Behavior; Drug Evaluation, Preclinical; Feeding Behavior; Grooming; Ketamine; Male; Modafinil; Motor Activity; Nicotine; Psychotropic Drugs; Rats; Rats, Wistar | 2012 |
Common influences of non-competitive NMDA receptor antagonists on the consolidation and reconsolidation of cocaine-cue memory.
Topics: Animals; Cocaine; Conditioning, Psychological; Cues; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memantine; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reward | 2013 |
Comparison of the MK-801-induced increase in non-rewarded appetitive responding with dopamine agonists and locomotor activity in rats.
Topics: Animals; Apomorphine; Cocaine; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Extinction, Psychological; Male; Motor Activity; Piperazines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2013 |
Continuous exposure to dizocilpine facilitates escalation of cocaine consumption in male Sprague-Dawley rats.
Topics: Animals; Behavior, Addictive; Cocaine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Self Administration | 2014 |
Incubation of cocaine seeking following brief cocaine experience in mice is enhanced by mGluR1 blockade.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cocaine; Conditioning, Operant; Cues; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extinction, Psychological; Food; Heterocyclic Compounds, 3-Ring; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Protein Binding; Receptors, Metabotropic Glutamate; Self Administration; Time Factors; Tritium | 2014 |
Dissociable effects of the noncompetitive NMDA receptor antagonists ketamine and MK-801 on intracranial self-stimulation in rats.
Topics: Anesthetics, Dissociative; Animals; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Medial Forebrain Bundle; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Self Stimulation; Substance-Related Disorders; Time Factors | 2014 |
Retrieval-induced NMDA receptor-dependent Arc expression in two models of cocaine-cue memory.
Topics: Animals; Brain; Cocaine; Cues; Cytoskeletal Proteins; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Memantine; Memory; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2014 |
Variations in the stimulus salience of cocaine reward influences drug-associated contextual memory.
Topics: Aminoacetonitrile; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Male; Memory; Mice, Inbred C57BL; Nitric Oxide Synthase Type I; Piperidines; Receptors, N-Methyl-D-Aspartate; Reward | 2016 |
Continuous exposure to dizocilpine facilitates the acquisition and escalation of cocaine consumption in male Sprague-Dawley rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Infusions, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reinforcement Schedule; Self Administration | 2015 |
Cell type-specific pharmacology of NMDA receptors using masked MK801.
Topics: Animals; Cocaine; Dizocilpine Maleate; Dopaminergic Neurons; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate | 2015 |
NMDA and dopamine D1 receptors within NAc-shell regulate IEG proteins expression in reward circuit during cocaine memory reconsolidation.
Topics: Animals; Benzazepines; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Early Growth Response Protein 1; Genes, Immediate-Early; Male; Memory; Neural Pathways; Neurotransmitter Agents; Nucleus Accumbens; Propranolol; Proto-Oncogene Proteins c-fos; Raclopride; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reward; Spatial Behavior | 2016 |
NMDA antagonist MK 801 in nucleus accumbens core but not shell disrupts the restraint stress-induced reinstatement of extinguished cocaine-conditioned place preference in rats.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Extinction, Psychological; Locomotion; Male; Nucleus Accumbens; Rats; Rats, Wistar; Restraint, Physical; Time Factors | 2016 |
NMDAR dependent intracellular responses associated with cocaine conditioned place preference behavior.
Topics: Animals; Cocaine; Conditioning, Classical; CREB-Binding Protein; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Down-Regulation; Excitatory Amino Acid Antagonists; Globus Pallidus; Locomotion; Male; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sirtuin 1; Sirtuin 2; Time Factors | 2017 |
Blockade of NMDA receptors blocks the acquisition of cocaine conditioned approach in rats.
Topics: Animals; Cocaine; Conditioning, Psychological; Dizocilpine Maleate; Male; Rats; Receptors, N-Methyl-D-Aspartate; Reward | 2018 |
Differences in trait impulsivity do not bias the response to pharmacological drug challenge in the rat five-choice serial reaction time task.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Attention; Choice Behavior; Cocaine; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Impulsive Behavior; Male; Phenotype; Rats; Reaction Time; Yohimbine | 2018 |
Increased sensitivity to psychostimulants and GABAergic drugs in Lsamp-deficient mice.
Topics: Alprazolam; Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Ethanol; Female; GABA Modulators; Gene Knockout Techniques; GPI-Linked Proteins; Locomotion; Male; Maze Learning; Mice; Mice, Knockout; Morphine; Neuroprotective Agents; Phenotype; Receptors, GABA-A | 2019 |
Factors regulating serine racemase and d-amino acid oxidase expression in the mouse striatum.
Topics: Animals; Brain; Cocaine; Corpus Striatum; D-Amino-Acid Oxidase; Dizocilpine Maleate; Female; Gene Expression; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Quinoxalines; Racemases and Epimerases; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Serine | 2021 |
Effects of JL13, a pyridobenzoxazepine compound, in dopaminergic and glutamatergic models of antipsychotic activity.
Topics: Animals; Antipsychotic Agents; Cocaine; Disease Models, Animal; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Ketamine; Locomotion; Male; Mice; Oxazepines; Piperazines; Pyridines; Reflex, Startle; Schizophrenia | 2021 |
In Vitro Selection of Short DNA Aptamers that Can Inhibit or Alleviate Cocaine and MK-801 Inhibition of Muscle-Type Nicotinic Acetylcholine Receptors.
Topics: Animals; Aptamers, Nucleotide; Cell Line; Cocaine; Dizocilpine Maleate; Mammals; Muscles; Receptors, Nicotinic | 2022 |
Effects of NMDA receptor antagonists on behavioral economic indices of cocaine self-administration.
Topics: Animals; Cocaine; Dizocilpine Maleate; Economics, Behavioral; Female; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Self Administration | 2022 |