cocaine has been researched along with citalopram in 73 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 22 (30.14) | 18.2507 |
2000's | 35 (47.95) | 29.6817 |
2010's | 14 (19.18) | 24.3611 |
2020's | 2 (2.74) | 2.80 |
Authors | Studies |
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Sen, S; Sinha, N | 1 |
Keserü, GM | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Alagille, D; Baldessarini, RJ; Baldwin, RM; Fu, X; Innis, RB; Kula, NS; Tamagnan, G | 1 |
Nagashima, R; Nishikawa, T; Tobita, M | 1 |
Jolivette, LJ; Ward, KW | 1 |
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Jia, L; Sun, H | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Anestis, DK; Gruetter, CA; Lemke, SM; Szarek, JL; Valentovic, MA | 1 |
Spealman, RD | 1 |
Dewey, SL; Fowler, JS; Gatley, SJ; Logan, J; Volkow, ND | 1 |
al-Tikriti, MS; Baldwin, RM; Laruelle, M; Malison, RT; Neumeyer, JL; Sybirska, EH; Wisniewski, G; Zea-Ponce, Y; Zimmermann, RC; Zoghbi, SS | 1 |
Dewey, SL; Fowler, JS; Gatley, SJ; King, P; Logan, J; MacGregor, RR; Pappas, N; Schlyer, DJ; Volkow, ND; wang, GJ | 1 |
Elliott, P; Wallis, DI | 1 |
Chen, NH; Reith, ME | 1 |
Dutta, AK; Madras, BK; Meltzer, PC; Reith, ME | 1 |
Patel, A | 1 |
Baldwin, RM; Charney, DS; Giddings, SS; Innis, RB; Laruelle, M; Neumeyer, JL; Zea-Ponce, Y | 1 |
Baraban, JM; Bhat, RV | 1 |
Angelberger, P; Asenbaum, S; Brücke, T; Deecke, L; Kasper, S; Koch, G; Pirker, W; Podreka, I; Pozzera, A; Walter, H | 1 |
Byon, C; Elmaleh, DR; Fischman, AJ; Hanson, RN; Liang, AY; Madras, BK; Meltzer, PC; Shoup, TM | 1 |
Coffey, LL; Dutta, AK; Reith, ME | 1 |
Gerhardt, GA; Hoffman, AF; Lupica, CR; Zahniser, NR | 1 |
Babich, J; Elmaleh, DR; Fischman, AJ; Liang, AY; Madras, BK; Meltzer, PC | 1 |
Bennett, BA; Childers, SR; Daunais, JB; Davies, HM; Hart, SL; Letchworth, SR; Porrino, LJ; Sexton, T; Smith, HR | 1 |
Dutta, AK; Reith, ME; Xu, C | 1 |
Battaglia, G; Carroll, FI; Kuhar, MJ; Vicentic, A | 1 |
Dewar, KM | 1 |
Besnard, JC; Bottlaender, M; Chalon, S; Coulon, C; Emond, P; Frangin, Y; Fuseau, C; Guenther, I; Guilloteau, D; Helfenbein, J; Loc'h, C; Maziere, B; Ottaviani, M | 1 |
Blundell, P; Gonzalez, MD; Liang, AY; Madras, BK; Meltzer, PC; Niznik, HB; Pristupa, ZB | 1 |
Blundell, P; Huang, H; Liu, S; Madras, BK; Meltzer, PC; Yong, YF | 1 |
Brissie, RM; Fu, K; Hardy, RW; Konrad, RJ; Robinson, CA | 1 |
Carroll, FI; Gether, U; Jensen, AD; Maresch, MJ; Rasmussen, SG; Tate, CG | 1 |
Davis, MC; Dutta, AK; Reith, ME | 1 |
Yan, QS | 1 |
Arai, S; Dohi, T; Kihira, K; Kitayama, S; Kumagai, K; Kumagai, M; Morita, K | 1 |
De Deurwaerdère, P; Moison, D; Porras, G; Spampinato, U | 1 |
Dahl, SG; Ravna, AW; Sylte, I | 1 |
Baker, GB; Fletcher, PJ; Salsali, M; Sinyard, J | 1 |
Platt, DM; Rowlett, JK; Spealman, RD | 1 |
Madras, BK; Meltzer, PC; Pham-Huu, DP | 1 |
Booij, J; de Win, MM; den Heeten, GJ; Habraken, JB; Reneman, L; van den Brink, W | 1 |
Goodman, MM; Jarkas, N; McConathy, J; Voll, RJ | 1 |
Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH | 1 |
Dahl, SG; Kristiansen, K; Ravna, AW; Sylte, I | 1 |
Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF | 1 |
Angermeyer, MC; Barthel, H; Hesse, S; Müller, U; Sabri, O; Stengler-Wenzke, K | 1 |
Fukushima, S; Hall, FS; Kobayashi, H; Numachi, Y; Shen, HW; Sora, I; Uhl, GR; Yamashita, M | 1 |
Cherng, CF; Hsiao, SY; Yang, YK; Yeh, TL; Yu, L | 1 |
Bottoncetti, A; Cini, N; Danieli, E; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
Ravna, AW | 1 |
Deutsch, HM; Kim, DI; Schweri, MM; Ye, X | 1 |
Gottardo, R; Pascali, JP; Polettini, A; Tagliaro, F | 1 |
Aberg, M; Collins, SL; Fernandez, JB; Izenwasser, S; Kumar, A; Zakharova, E | 1 |
Nikiforuk, A; Popik, P | 1 |
Kittler, K; Lau, T; Schloss, P | 1 |
Hiranita, T; Katz, JL; Soto, PL | 1 |
Choi, SH; Kang, S; Kim, HJ; Lee, MS; Shin, KH; Shin, SK | 1 |
Fisar, Z; Hroudová, J; Raboch, J | 1 |
Amara, SG; Larsen, MB; Larson, GA; Mortensen, OV; Sonders, MS; Zahniser, NR | 1 |
Cunningham, KA; John, VP; Lane, SD; Liu, S; Moeller, FG; Schmitz, JM | 1 |
Anagnostaras, SG; Carmack, SA; Howell, KK; Rasaei, K; Reas, ET | 1 |
Chen, HX; Gao, N; Jin, ZL; Li, XR; Li, YF; Tang, Y; Xiong, J; Zhang, JR | 1 |
De La Garza, R; Haile, CN; Mahoney, JJ; Newton, TF; Thompson-Lake, DG; Verrico, CD | 1 |
Gu, HH; Hadden, C; Kilic, F; Li, Y; Lowery, CL; Mercado, CP; Singh, P; Ucer, SS; Ziu, E | 1 |
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M | 1 |
Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E; Suder, A; Wydra, K | 1 |
Baillif-Couniou, V; Champeaux-Fesquet, C; Christia, MA; Deveaux, M; Leonetti, G; Pélissier-Alicot, AL; Sastre, C | 1 |
de Dios, C; Green, CE; Lane, SD; Moeller, FG; Schmitz, JM; Suchting, R; Vincent, J | 1 |
1 review(s) available for cocaine and citalopram
Article | Year |
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Three-dimensional models of neurotransmitter transporters and their interactions with cocaine and S-citalopram.
Topics: Antidepressive Agents; Citalopram; Cocaine; Depressive Disorder; Models, Molecular; Neurotransmitter Transport Proteins; Protein Conformation; Reward | 2006 |
5 trial(s) available for cocaine and citalopram
Article | Year |
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Validation of [(123)I]beta-CIT SPECT to assess serotonin transporters in vivo in humans: a double-blind, placebo-controlled, crossover study with the selective serotonin reuptake inhibitor citalopram.
Topics: Adolescent; Adult; Brain; Brain Chemistry; Citalopram; Cocaine; Cross-Over Studies; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Radiopharmaceuticals; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 2005 |
Serotonin transporter imaging with [123I]beta-CIT SPECT before and after one year of citalopram treatment of obsessive-compulsive disorder.
Topics: Adult; Brain; Brain Stem; Citalopram; Cocaine; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Female; Humans; Magnetic Resonance Imaging; Male; Mesencephalon; Obsessive-Compulsive Disorder; Radiopharmaceuticals; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Thalamus; Tomography, Emission-Computed, Single-Photon | 2006 |
Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects.
Topics: Adult; Attention; Citalopram; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Users; Female; Humans; Male; Memory, Short-Term; Selective Serotonin Reuptake Inhibitors; Serotonin | 2013 |
Treatment with modafinil and escitalopram, alone and in combination, on cocaine-induced effects: a randomized, double blind, placebo-controlled human laboratory study.
Topics: Adult; Affect; Benzhydryl Compounds; Blood Pressure; Choice Behavior; Citalopram; Cocaine; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Male; Middle Aged; Modafinil; Selective Serotonin Reuptake Inhibitors | 2014 |
Citalopram for treatment of cocaine use disorder: A Bayesian drop-the-loser randomized clinical trial.
Topics: Adult; Bayes Theorem; Citalopram; Cocaine; Double-Blind Method; Humans; Treatment Outcome | 2021 |
67 other study(ies) available for cocaine and citalopram
Article | Year |
---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.
Topics: Animals; Cerebral Cortex; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters; Tropanes | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Potentiation of 5-hydroxytryptamine-induced contraction in rat aorta by chlorpheniramine, citalopram and fluoxetine.
Topics: Animals; Aorta, Thoracic; Chlorpheniramine; Citalopram; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Male; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstriction | 1992 |
Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Animals; Citalopram; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Narcotics; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Receptors, Adrenergic, alpha; Saimiri; Selective Serotonin Reuptake Inhibitors | 1995 |
Sensitivity of striatal [11C]cocaine binding to decreases in synaptic dopamine.
Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Presynaptic Terminals; Time Factors; Tomography, Emission-Computed | 1995 |
SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.
Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Chlorocebus aethiops; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Indans; Iodine Radioisotopes; Levodopa; Ligands; Maprotiline; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Papio; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon | 1993 |
Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.
Topics: Animals; Binding Sites; Brain; Carbon Radioisotopes; Carrier Proteins; Cerebellum; Citalopram; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Papio; Serotonin; Tomography, Emission-Computed | 1995 |
Glutamatergic and non-glutamatergic responses evoked in neonatal rat lumbar motoneurons on stimulation of the lateroventral spinal cord surface.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Bicuculline; Citalopram; Cocaine; Desipramine; Electric Stimulation; Ergolines; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Serotonin Antagonists; Spinal Cord; Strychnine; Synapses | 1993 |
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.
Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area | 1994 |
O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen.
Topics: Animals; Carrier Proteins; Caudate Nucleus; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Piperidines; Protein Binding; Putamen; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1994 |
Characterization of [125I]RTI-55 binding to dog caudate dopamine transporter.
Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cell Membrane; Cholic Acids; Citalopram; Cocaine; Desipramine; Dogs; Dopamine Plasma Membrane Transport Proteins; Filtration; Iodine Radioisotopes; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Solubility | 1993 |
Methyl 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylate in vitro binding to dopamine and serotonin transporters under "physiological" conditions.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cerebral Cortex; Citalopram; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Temperature; Tomography, Emission-Computed, Single-Photon | 1994 |
Activation of transcription factor genes in striatum by cocaine: role of both serotonin and dopamine systems.
Topics: Animals; Citalopram; Cocaine; DNA-Binding Proteins; Dopamine; Early Growth Response Protein 1; Gene Expression; Genes, fos; Immediate-Early Proteins; In Situ Hybridization; Male; Mazindol; Neurotransmitter Uptake Inhibitors; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA Probes; Serotonin; Transcription Factors | 1993 |
beta-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo.
Topics: Adult; Aged; Brain Chemistry; Brain Stem; Citalopram; Cocaine; Female; Humans; Hypothalamus; Iodine Radioisotopes; Ligands; Male; Middle Aged; Neostriatum; Selective Serotonin Reuptake Inhibitors; Serotonin; Tomography, Emission-Computed, Single-Photon | 1995 |
Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites.
Topics: Animals; Autoradiography; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Saimiri; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon | 1996 |
Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
Topics: Animals; Carrier Proteins; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats | 1997 |
Voltage-dependency of the dopamine transporter in rat brain.
Topics: Animals; Brain; Carrier Proteins; Caudate Nucleus; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Electric Stimulation; In Vitro Techniques; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Putamen; Rats; Substantia Nigra | 1998 |
Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain.
Topics: Animals; Brain; Brain Chemistry; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Iodine Radioisotopes; Ligands; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Receptors, Dopamine D1; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 1998 |
Long-acting blockade of biogenic amine transporters in rat brain by administration of the potent novel tropane 2beta-propanoyl-3beta-(2-Naphthyl)-tropane.
Topics: Animals; Binding, Competitive; Biogenic Amines; Biological Transport; Brain; Cell Membrane; Citalopram; Cocaine; Dopamine; Drug Interactions; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Tropanes | 1998 |
Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
Topics: Animals; Carrier Proteins; Cell Line; Citalopram; Cloning, Molecular; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Transfection | 1998 |
Serotonin transporter production and degradation rates: studies with RTI-76.
Topics: Animals; Carrier Proteins; Cerebral Cortex; Cerebral Ventricles; Citalopram; Cocaine; Half-Life; Injections, Intraventricular; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Neurological; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tropanes | 1999 |
Alterations in serotonin receptors in the neostriatum of weaver mutant mice.
Topics: Amphetamines; Animals; Citalopram; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Mice; Mice, Neurologic Mutants; Mutation; Neostriatum; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Tritium | 1999 |
A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: pharmacological evaluation and PET experiments.
Topics: Animals; Brain; Bromine Radioisotopes; Cerebellum; Cerebral Cortex; Citalopram; Cocaine; Corpus Striatum; Dopamine; Kinetics; Male; Maprotiline; Nortropanes; Papio; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Thalamus; Tissue Distribution; Tomography, Emission-Computed | 1999 |
Nitrogen-based drugs are not essential for blockade of monoamine transporters.
Topics: Animals; Binding Sites; Carrier Proteins; Citalopram; Cocaine; COS Cells; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nitrogen; Norepinephrine; Putamen; Radioligand Assay | 1996 |
3-Aryl-2-carbomethoxybicyclo[3.2.1]oct-2-enes inhibit WIN 35,428 binding potently and selectively at the dopamine transporter.
Topics: Animals; Binding, Competitive; Brain Chemistry; Bridged Bicyclo Compounds; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Macaca fascicularis; Male; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tritium | 2000 |
An unusual multiple drug intoxication case involving citalopram.
Topics: Antidepressive Agents, Second-Generation; Citalopram; Cocaine; Dextropropoxyphene; Drug Synergism; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Oxycodone; Promethazine; Selective Serotonin Reuptake Inhibitors; Tissue Distribution | 2000 |
Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter.
Topics: Animals; Binding Sites; Carrier Proteins; Citalopram; Cocaine; Fluorescent Dyes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Protein Binding; Rats; Recombinant Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spectrometry, Fluorescence; Spodoptera; Transfection | 2001 |
Rational design and synthesis of novel 2,5-disubstituted cis- and trans-piperidine derivatives exhibiting differential activity for the dopamine transporter.
Topics: Benzhydryl Compounds; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Drug Evaluation, Preclinical; Isomerism; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2001 |
Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure.
Topics: Animals; Animals, Newborn; Citalopram; Cocaine; Cocaine-Related Disorders; Electric Stimulation; Female; Fenfluramine; Fetus; Fluoxetine; Methiothepin; Neostriatum; Nucleus Accumbens; p-Chloroamphetamine; Potassium; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2002 |
Chronic inhibition of the norepinephrine transporter in the brain participates in seizure sensitization to cocaine and local anesthetics.
Topics: Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Brain; Brain Chemistry; Citalopram; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Lidocaine; Male; Maprotiline; Mice; Mice, Inbred ICR; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Seizures; Selective Serotonin Reuptake Inhibitors; Symporters; Time Factors | 2003 |
Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.
Topics: Amphetamine; Analgesics, Opioid; Animals; Brain Chemistry; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Electrochemistry; Haloperidol; Male; Microdialysis; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT3 Receptor Antagonists; Tropanes | 2003 |
Molecular mechanism of citalopram and cocaine interactions with neurotransmitter transporters.
Topics: Animals; Binding Sites; Carrier Proteins; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Protein Structure, Tertiary; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters | 2003 |
Fluoxetine, but not sertraline or citalopram, potentiates the locomotor stimulant effect of cocaine: possible pharmacokinetic effects.
Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Citalopram; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Sertraline; Tissue Distribution | 2004 |
Cocaine-like discriminative stimulus effects of heroin: modulation by selective monoamine transport inhibitors.
Topics: Animals; Carrier Proteins; Citalopram; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Heroin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuropeptides; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Saimiri; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiophenes; Vesicular Biogenic Amine Transport Proteins | 2004 |
Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters.
Topics: Alkenes; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2004 |
Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.
Topics: Benzylamines; Binding, Competitive; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Isotope Labeling; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Radiopharmaceuticals; Recombinant Proteins; Serotonin Plasma Membrane Transport Proteins; Sulfides; Symporters; Tritium | 2005 |
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.
Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine | 2005 |
Putative drug binding conformations of monoamine transporters.
Topics: Amino Acid Sequence; Amphetamine; Binding Sites; Biogenic Monoamines; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Humans; In Vitro Techniques; Ligands; Models, Molecular; Molecular Sequence Data; Norepinephrine Plasma Membrane Transport Proteins; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Sequence Homology, Amino Acid; Serotonin Plasma Membrane Transport Proteins; Symporters; Thermodynamics | 2006 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice.
Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Inhibition, Psychological; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine Plasma Membrane Transport Proteins; Reaction Time; Reflex, Startle; Selective Serotonin Reuptake Inhibitors | 2006 |
Prenatal bupropion exposure enhances the cocaine reward and stress susceptibility in adult mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Bupropion; Citalopram; Cocaine; Conditioning, Operant; Female; Fluvoxamine; Male; Maternal Behavior; Mice; Mice, Inbred C57BL; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Stress, Physiological; Trazodone | 2005 |
3-Aza-6,8-dioxabicyclo[3.2.1]octanes as new enantiopure heteroatom-rich tropane-like ligands of human dopamine transporter.
Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; CHO Cells; Citalopram; Cocaine; Cricetinae; Dopamine Plasma Membrane Transport Proteins; Humans; Ligands; Models, Molecular; Molecular Conformation; Recombinant Proteins; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tropanes | 2006 |
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Male; Methylphenidate; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship | 2007 |
Implementation and performance evaluation of a database of chemical formulas for the screening of pharmaco/toxicologically relevant compounds in biological samples using electrospray ionization-time-of-flight mass spectrometry.
Topics: Chlorpromazine; Citalopram; Cocaine; Female; Hair; Hazardous Substances; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization; Suicide | 2008 |
Depletion of serotonin decreases the effects of the kappa-opioid receptor agonist U-69593 on cocaine-stimulated activity.
Topics: Animals; Autoradiography; Benzeneacetamides; Brain Chemistry; Citalopram; Cocaine; In Vitro Techniques; Male; Motor Activity; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2008 |
Antidepressants alleviate the impact of reinforcer downshift.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central Nervous System Stimulants; Chlordiazepoxide; Citalopram; Cocaine; Conditioning, Operant; Desipramine; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors | 2009 |
Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons.
Topics: Animals; Cell Line; Citalopram; Cocaine; Gene Expression Regulation; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Protein Transport; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2010 |
Citalopram enhances cocaine's subjective effects in rats.
Topics: Animals; Citalopram; Cocaine; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Species Specificity | 2009 |
Effects of reboxetine and citalopram pretreatment on changes in cocaine and amphetamine regulated transcript (CART) expression in rat brain induced by the forced swimming test.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Amygdala; Animals; Behavior, Animal; Citalopram; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Locus Coeruleus; Male; Morpholines; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reboxetine; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Swimming | 2010 |
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride | 2010 |
Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation.
Topics: Analysis of Variance; Animals; CA3 Region, Hippocampal; Cell Line, Transformed; Chlorocebus aethiops; Citalopram; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Electrochemical Techniques; Humans; Male; Mutagenesis, Site-Directed; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sodium; Transfection; Tritium | 2011 |
Animal model of methylphenidate's long-term memory-enhancing effects.
Topics: Adrenergic Uptake Inhibitors; Amphetamine; Animals; Atomoxetine Hydrochloride; Bupropion; Central Nervous System Stimulants; Citalopram; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Female; Locomotion; Male; Maze Learning; Memory, Long-Term; Methylphenidate; Mice; Mice, Inbred C57BL; Nootropic Agents; Propylamines; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Space Perception | 2014 |
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
Topics: Animals; Antidepressive Agents; Citalopram; Cocaine; Depression; Disease Models, Animal; Female; Fluoxetine; Male; Medicine, Chinese Traditional; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Saponins; Swimming; Tritium | 2014 |
Effect of serotonin on platelet function in cocaine exposed blood.
Topics: Animals; Blood Coagulation Tests; Blood Platelets; Catecholamines; Cells, Cultured; Citalopram; Cocaine; Collagen Type I; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Gene Knock-In Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Platelet Activation; Platelet Aggregation; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2014 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Effects of escitalopram and imipramine on cocaine reinforcement and drug-seeking behaviors in a rat model of depression.
Topics: Animals; Citalopram; Cocaine; Cocaine-Related Disorders; Cues; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Imipramine; Male; Motor Activity; Olfactory Bulb; Psychotropic Drugs; Rats, Wistar; Reinforcement, Psychology; Self Administration | 2017 |
Planned complex suicide involving combined drug intoxication and femoral catheterization.
Topics: Adult; Antidepressive Agents, Second-Generation; Catheterization; Chromatography, Liquid; Citalopram; Cocaine; Cocaine-Related Disorders; Depressive Disorder, Major; Drug Overdose; Femoral Artery; Gas Chromatography-Mass Spectrometry; Humans; Male; Narcotics; Suicide, Completed | 2021 |