cocaine and buspirone

cocaine has been researched along with buspirone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's9 (32.14)18.2507
2000's3 (10.71)29.6817
2010's14 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sen, S; Sinha, N1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Glennon, RA1
Balster, RL; Gold, LH1
Balster, RL; Woolverton, WL1
Cherek, DR; Fulton, M; Garver, DL; Kramer, G; Moeller, FG; Petty, F; Steinberg, JL1
Ator, NA; Griffiths, RR; Sannerud, CA1
Aceto, MD; Bowman, ER1
Rapoza, D1
Callahan, PM; Cunningham, KA1
Ali, I; Kelly, ME1
Anderson, KG; van Haaren, F1
Carey, R; Damianopoulos, E; DePalma, G1
Jackman, SL; Olmstead, MC; Paine, TA1
Bernardi, RE; Ettenberg, A2
Bruckmann, W; De Vry, J; Rutten, K; Tzschentke, TM; Van Der Kam, EL1
da Silva, FC; de Oliveira Citó, Mdo C; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macêdo, DS; Moura, BA; Silva, MI; Woods, DJ1
Bergman, J; Conroy, JL; Furman, CA; Mello, NK; Roof, RA; Sibley, DR; Skolnick, P1
Bergman, J; Fivel, PA; Kohut, SJ; Mello, NK1
Fivel, PA; Kohut, SJ; Mello, NK1
Beardsley, PM; Hendrick, ES; Shelton, KL1
Banala, AK; John, WS; Nader, MA; Newman, AH1
Czoty, PW; Nader, MA1
Beckmann, JS; Bolin, BL; Lile, JA; Marks, KR; Rush, CR; Stoops, WW1
Collins, GT; France, CP1

Trials

1 trial(s) available for cocaine and buspirone

ArticleYear
Serotonin and impulsive/aggressive behavior in cocaine dependent subjects.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:6

    Topics: Adult; Aggression; Buspirone; Cocaine; Growth Hormone; Humans; Impulsive Behavior; Male; Psychiatric Status Rating Scales; Serotonin; Single-Blind Method; Substance-Related Disorders

1994

Other Studies

27 other study(ies) available for cocaine and buspirone

ArticleYear
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
Effects of buspirone and gepirone on i.v. cocaine self-administration in rhesus monkeys.
    Psychopharmacology, 1992, Volume: 108, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Chlorpromazine; Cocaine; Conditioning, Operant; Injections, Intravenous; Macaca mulatta; Male; Pyrimidines; Reinforcement Schedule; Self Administration

1992
Intravenous buspirone self-administration in rhesus monkeys.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:12 Pt 2

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Chlordiazepoxide; Clorazepate Dipotassium; Cocaine; Conditioning, Operant; Injections, Intravenous; Macaca mulatta; Pyrimidines; Reinforcement, Psychology; Self Administration; Sodium Chloride

1982
Behavioral pharmacology of tandospirone in baboons: chronic administration and withdrawal, self-injection and drug discrimination.
    Drug and alcohol dependence, 1993, Volume: 32, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Arousal; Buspirone; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Eating; Flumazenil; Isoindoles; Lorazepam; Male; Motor Skills; Neurologic Examination; Papio; Pentobarbital; Piperazines; Pyrimidines; Reinforcement Schedule; Self Administration; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Substance-Related Disorders

1993
Suppression of opiate withdrawal and cocaine hyperarousal syndromes by buspirone. Possible pharmacotherapeutic applications.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:9

    Topics: Animals; Arousal; Buspirone; Cocaine; Female; Macaca mulatta; Male; Morphine; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome

1993
Buspirone fails to affect the discriminative stimulus effects of cocaine.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: Animals; Buspirone; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley

1993
Modulation of the discriminative stimulus properties of cocaine: comparison of the effects of fluoxetine with 5-HT1A and 5-HT1B receptor agonists.
    Neuropharmacology, 1997, Volume: 36, Issue:3

    Topics: Animals; Buspirone; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

1997
Buspirone fails to affect cocaine-induced conditioned place preference in the mouse.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:2

    Topics: Animals; Buspirone; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Mice; Serotonin Receptor Agonists

1997
Effects of chlordiazepoxide, buspirone and cocaine on behavior suppressed by timeout presentation.
    Behavioural pharmacology, 1997, Volume: 8, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Chlordiazepoxide; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Injections, Intraperitoneal; Male; Punishment; Rats; Rats, Wistar; Reinforcement Schedule; Reinforcement, Psychology

1997
Issues in the pharmacological modification of cocaine conditioning: evidence that the stimulus properties of drugs can interact with contextual cues to activate or inactivate cocaine conditioned stimuli.
    Behavioural brain research, 1999, Volume: 101, Issue:2

    Topics: Animals; Brain; Buspirone; Cocaine; Conditioning, Operant; Cues; Dizocilpine Maleate; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Grooming; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

1999
Cocaine-induced anxiety: alleviation by diazepam, but not buspirone, dimenhydrinate or diphenhydramine.
    Behavioural pharmacology, 2002, Volume: 13, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Cocaine; Conflict, Psychological; Diazepam; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Exploratory Behavior; Injections, Intraperitoneal; Male; Maze Learning; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome

2002
Anxiolytic-like actions of buspirone in a runway model of intravenous cocaine self-administration.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Cocaine; Injections, Intravenous; Male; Rats; Reward; Self Administration; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists

2006
Effects of buspirone on the immediate positive and delayed negative properties of intravenous cocaine as measured in the conditioned place preference test.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:1

    Topics: Animals; Anxiety; Buspirone; Cocaine; Conditioning, Operant; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reward; Serotonin; Serotonin Receptor Agonists; Synapses

2007
The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats.
    Addiction biology, 2011, Volume: 16, Issue:1

    Topics: Animals; Brain; Buspirone; Choice Behavior; Clonidine; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Synergism; Illicit Drugs; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Nicotine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Social Environment; Substance-Related Disorders

2011
Reversal of cocaine withdrawal-induced anxiety by ondansetron, buspirone and propranolol.
    Behavioural brain research, 2012, May-16, Volume: 231, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Cocaine; Male; Motor Activity; Ondansetron; Propranolol; Rats; Rats, Wistar; Substance Withdrawal Syndrome

2012
Modification of cocaine self-administration by buspirone (buspar®): potential involvement of D3 and D4 dopamine receptors.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:2

    Topics: Analysis of Variance; Animals; Buspirone; Cocaine; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; G Protein-Coupled Inwardly-Rectifying Potassium Channels; HEK293 Cells; Humans; Macaca mulatta; Male; Protein Binding; Receptors, Dopamine D3; Receptors, Dopamine D4; Self Administration; Serotonin; Serotonin Receptor Agonists; Tritium

2013
Effects of chronic buspirone treatment on cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Behavior, Addictive; Buspirone; Cocaine; Eating; Macaca mulatta; Male; Self Administration; Treatment Outcome

2013
Effects of chronic buspirone treatment on nicotine and concurrent nicotine+cocaine self-administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Macaca mulatta; Nicotine; Nicotinic Agonists; Reinforcement Schedule; Self Administration

2013
Efficacy of buspirone for attenuating cocaine and methamphetamine reinstatement in rats.
    Drug and alcohol dependence, 2013, May-01, Volume: 129, Issue:3

    Topics: Animals; Behavior, Addictive; Buspirone; Cocaine; Conditioning, Operant; Male; Methamphetamine; Rats; Rats, Long-Evans; Reaction Time; Reinforcement, Psychology; Self Administration; Treatment Outcome

2013
Effects of buspirone and the dopamine D3 receptor compound PG619 on cocaine and methamphetamine self-administration in rhesus monkeys using a food-drug choice paradigm.
    Psychopharmacology, 2015, Volume: 232, Issue:7

    Topics: Animals; Buspirone; Choice Behavior; Cocaine; Dopamine Agonists; Dose-Response Relationship, Drug; Feeding Behavior; Follow-Up Studies; Macaca mulatta; Male; Methamphetamine; Receptors, Dopamine D3; Reinforcement, Psychology; Self Administration

2015
Effects of oral and intravenous administration of buspirone on food-cocaine choice in socially housed male cynomolgus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Mar-13, Volume: 40, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Animals; Benzamides; Buspirone; Catheters, Indwelling; Choice Behavior; Cocaine; Cocaine-Related Disorders; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Feeding Behavior; Housing, Animal; Macaca fascicularis; Male; Pyridines; Self Administration; Social Dominance

2015
Buspirone reduces sexual risk-taking intent but not cocaine self-administration.
    Experimental and clinical psychopharmacology, 2016, Volume: 24, Issue:3

    Topics: Adult; Buspirone; Cocaine; Cocaine-Related Disorders; Condoms; Cross-Over Studies; Delay Discounting; Double-Blind Method; Female; Humans; Impulsive Behavior; Male; Middle Aged; Reinforcement, Psychology; Risk-Taking; Self Administration; Sexual Behavior; Sexually Transmitted Diseases; Unsafe Sex

2016
Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self-administration in male and female rhesus monkeys.
    Experimental and clinical psychopharmacology, 2018, Volume: 26, Issue:5

    Topics: Animals; Behavior, Addictive; Benzazepines; Buspirone; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Female; Macaca mulatta; Male; Serotonin Receptor Agonists

2018