cocaine and bupivacaine

cocaine has been researched along with bupivacaine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19908 (30.77)18.7374
1990's7 (26.92)18.2507
2000's7 (26.92)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brouillette, WJ; Brown, GB; Zha, C1
Wang, GK; Wang, SY1
Cook, JA; Evans, K; Lavelle, RJ; Murrant, NJ1
Wang, GK1
Finstuen, K; Henneberger, JT; Menk, EJ; Middaugh, RE1
Belt, WD; Benoit, PW1
Bahar, M; Flecknell, P; Nunn, JF; Rosen, M1
Bahar, M; Cole, G; Rosen, M; Vickers, MD1
Covino, BG; Gissen, AJ; Gregus, J1
Harkins, JD; Mundy, GD; Rees, WA; Stanley, S; Thompson, KN; Tobin, T; Woods, WE1
Hackenberg, D; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD1
Kuhn, M; Plummer, JL; Raftos, J; Rossi, SO1
Ebert, B; Ganser, J1
Barrett, T; Cohen, DM; Harbeck-Weber, C; Powers, JD; Shields, BJ; Smith, GA; Strausbaugh, SD1
Böni, T; Borgeat, A; Ruetsch, YA1
Cox, B; Durieux, ME; Marcus, MA1
Dennis, D; Lee, YH; Morey, T; Partch, R; Powell, E; Varshney, M1
Morrell, JI; Seip, KM1
Morrell, JI; Pereira, M1
Feinstein, DL; Fettiplace, MR; Kowal, K; Lin, B; Lis, K; Pichurko, A; Ripper, R; Rubinstein, I; Schwartz, D; Weinberg, G1

Reviews

2 review(s) available for cocaine and bupivacaine

ArticleYear
From cocaine to ropivacaine: the history of local anesthetic drugs.
    Current topics in medicinal chemistry, 2001, Volume: 1, Issue:3

    Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Cocaine; Europe; History, 19th Century; History, 20th Century; Humans; North America; Ropivacaine

2001
Toxicity of local anaesthetics.
    Best practice & research. Clinical anaesthesiology, 2003, Volume: 17, Issue:1

    Topics: Anesthetics, Local; Animals; Bupivacaine; Cardiovascular System; Cocaine; Drug Hypersensitivity; Etidocaine; Humans; Lidocaine; Mepivacaine; Nervous System; Procaine; Tetracaine

2003

Trials

5 trial(s) available for cocaine and bupivacaine

ArticleYear
Manipulation of the fractured nose under local anaesthesia.
    Clinical otolaryngology and allied sciences, 1992, Volume: 17, Issue:4

    Topics: Adult; Airway Resistance; Anesthesia, Local; Bupivacaine; Cocaine; Female; Fractures, Bone; Humans; Male; Nasal Bone; Nerve Block; Nose; Pain Measurement

1992
Sphenopalatine ganglion blocks for the treatment of nicotine addiction.
    Southern medical journal, 1988, Volume: 81, Issue:7

    Topics: Anesthesia, Local; Bupivacaine; Clinical Trials as Topic; Cocaine; Double-Blind Method; Female; Ganglia, Parasympathetic; Ganglionic Blockers; Humans; Male; Middle Aged; Palate; Substance Withdrawal Syndrome; Tobacco Use Disorder

1988
Comparison of topical anesthetics without cocaine to tetracaine-adrenaline-cocaine and lidocaine infiltration during repair of lacerations: bupivacaine-norepinephrine is an effective new topical anesthetic agent.
    Pediatrics, 1996, Volume: 97, Issue:3

    Topics: Administration, Cutaneous; Adolescent; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cocaine; Double-Blind Method; Drug Combinations; Epinephrine; Female; Humans; Lidocaine; Male; Norepinephrine; Pain; Pain Measurement; Suture Techniques; Tetracaine; Wounds, Penetrating

1996
Topical anaesthesia for minor lacerations: MAC versus TAC.
    The Medical journal of Australia, 1996, Mar-04, Volume: 164, Issue:5

    Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Cocaine; Dermatologic Surgical Procedures; Epinephrine; Humans; Skin; Soft Tissue Injuries; Sutures; Tetracaine; Treatment Outcome

1996
Prilocaine-phenylephrine and bupivacaine-phenylephrine topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations.
    The American journal of emergency medicine, 1998, Volume: 16, Issue:2

    Topics: Adolescent; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Cocaine; Dermatologic Surgical Procedures; Double-Blind Method; Emergency Service, Hospital; Epinephrine; Female; Hospitals, Pediatric; Humans; Infant; Male; Pain; Pain Measurement; Phenylephrine; Prilocaine; Prospective Studies; Safety; Skin; Suture Techniques; Tetracaine; Vasoconstrictor Agents

1998

Other Studies

19 other study(ies) available for cocaine and bupivacaine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Which local anaesthetic?
    Drug and therapeutics bulletin, 1976, Feb-27, Volume: 14, Issue:5

    Topics: Administration, Topical; Anesthesia, Conduction; Anesthesia, Dental; Anesthesia, Inhalation; Anesthetics, Local; Bupivacaine; Cocaine; Humans; Lidocaine; Nerve Block; Prilocaine

1976
Altered stereoselectivity of cocaine and bupivacaine isomers in normal and batrachotoxin-modified Na+ channels.
    The Journal of general physiology, 1992, Volume: 100, Issue:6

    Topics: Batrachotoxins; Bupivacaine; Cell Membrane; Cells, Cultured; Cocaine; Electrophysiology; Sodium Channels; Stereoisomerism

1992
Cocaine-induced closures of single batrachotoxin-activated Na+ channels in planar lipid bilayers.
    The Journal of general physiology, 1988, Volume: 92, Issue:6

    Topics: Anesthetics, Local; Animals; Batrachotoxins; Binding Sites; Bupivacaine; Cocaine; Dose-Response Relationship, Drug; Electrophysiology; Lidocaine; Lipid Bilayers; Muscles; Rabbits; Sodium Channels

1988
Some effects of local anesthetic agents on skeletal muscle.
    Experimental neurology, 1972, Volume: 34, Issue:2

    Topics: Anesthesia, Local; Anesthetics; Animals; Bupivacaine; Cocaine; Lidocaine; Male; Mepivacaine; Muscles; Prilocaine; Procaine; Rats

1972
Differential sensory and motor blockade after spinal cocaine in the rat and marmoset.
    European journal of anaesthesiology, 1984, Volume: 1, Issue:1

    Topics: Analgesia; Anesthesia, Spinal; Animals; Bupivacaine; Callitrichinae; Cocaine; Dose-Response Relationship, Drug; Lidocaine; Male; Movement; Rats; Rats, Inbred Strains

1984
Histopathology of the spinal cord after intrathecal cocaine, bupivacaine, lignocaine and adrenaline in the rat.
    European journal of anaesthesiology, 1984, Volume: 1, Issue:3

    Topics: Animals; Bupivacaine; Catheterization; Cocaine; Epinephrine; Injections, Spinal; Lidocaine; Male; Neurons; Rats; Rats, Inbred Strains; Spinal Cord; Subarachnoid Space; Vacuoles

1984
Differential sensitivities of mammalian nerve fibers to local anesthetic agents.
    Anesthesiology, 1980, Volume: 53, Issue:6

    Topics: Anesthetics; Animals; Bupivacaine; Cocaine; Etidocaine; Lidocaine; Nerve Fibers; Nerve Fibers, Myelinated; Procaine; Rabbits; Saxitoxin; Tetracaine; Tetrodotoxin

1980
Determination of highest no effect dose (HNED) for local anaesthetic responses to procaine, cocaine, bupivacaine and benzocaine.
    Equine veterinary journal, 1996, Volume: 28, Issue:1

    Topics: Anesthetics, Local; Animals; Benzocaine; Body Temperature; Bupivacaine; Cocaine; Dose-Response Relationship, Drug; Female; Horses; Hot Temperature; Image Processing, Computer-Assisted; Procaine; Time Factors

1996
[Anesthesia and analgesia in intravenous drug dependent patients with injection abscesses of the upper extremity. Case report].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 1997, Volume: 29, Issue:1

    Topics: Abscess; Adult; Anesthesia, Conduction; Brachial Plexus; Bupivacaine; Cocaine; Etidocaine; Female; Hand; Humans; Mepivacaine; Methadone; Pain, Postoperative; Streptococcal Infections; Substance Abuse, Intravenous; Substance-Related Disorders

1997
Pi-Pi complexation of bupivacaine and analogues with aromatic receptors: implications for overdose remediation.
    International journal of nanomedicine, 2007, Volume: 2, Issue:3

    Topics: Animals; Bupivacaine; Chelating Agents; Chemistry, Pharmaceutical; Cocaine; Drug Carriers; Drug Overdose; Humans; Hydrocarbons, Aromatic; Sorption Detoxification

2007
Transient inactivation of the ventral tegmental area selectively disrupts the expression of conditioned place preference for pup- but not cocaine-paired contexts.
    Behavioral neuroscience, 2009, Volume: 123, Issue:6

    Topics: Analysis of Variance; Animals; Behavior, Animal; Bupivacaine; Catheters, Indwelling; Chi-Square Distribution; Cocaine; Conditioning, Psychological; Female; Maternal Behavior; Motivation; Motor Activity; Neural Inhibition; Rats; Rats, Sprague-Dawley; Self Administration; Ventral Tegmental Area

2009
The medial preoptic area is necessary for motivated choice of pup- over cocaine-associated environments by early postpartum rats.
    Neuroscience, 2010, May-05, Volume: 167, Issue:2

    Topics: Animals; Animals, Newborn; Bupivacaine; Choice Behavior; Cocaine; Conditioning, Classical; Cues; Female; Maternal Behavior; Motivation; Motor Activity; Preoptic Area; Rats; Reinforcement, Psychology

2010
Cardiac depression induced by cocaine or cocaethylene is alleviated by lipid emulsion more effectively than by sulfobutylether-β-cyclodextrin.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2015, Volume: 22, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; beta-Cyclodextrins; Bupivacaine; Cardiotoxicity; Cocaine; Coronary Circulation; Depression, Chemical; Fat Emulsions, Intravenous; Heart; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley

2015