cocaine and benztropine

cocaine has been researched along with benztropine in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (18.42)	18.7374
1990's	14 (18.42)	18.2507
2000's	32 (42.11)	29.6817
2010's	16 (21.05)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Allen, AC; George, C; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH	1
Allen, AC; Izenwasser, S; Katz, JL; Newman, AH	1
Bowen, WD; Izenwasser, S; Joseph, DB; Katz, JL; Kline, RH; Newman, AH	1
Baruchello, R; Bianchi, C; Borea, PA; Cavallini, S; Gessi, S; Invidiata, FP; Marino, S; Merighi, S; Roberti, M; Rondanin, R; Rossi, M; Simoni, D; Siniscalchi, A; Varani, K	1
Deutsch, HM; Kim, DI; Schweri, MM	1
Ball, WJ; Farr, CD; Norman, AB; Paula, S; Tabet, MR	1
Baruchello, R; Bertolasi, V; Bianchi, C; Borea, PA; Cavallini, S; Gessi, S; Grimaudo, S; Invidiata, FP; Marino, S; Merighi, S; Pizzirani, D; Roberti, M; Rondanin, R; Rossi, M; Simoni, D; Siniscalchi, A; Tolomeo, M; Varani, K	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Razdan, BK; Sasmal, D; Verma, SM	1
Heffner, TG; Stricker, EM; Zigmond, MJ	1
Barchas, JD; Patrick, RL	1
Moore, KE; Wuerthele, SM	1
Braestrup, C; Scheel-Krüger, J	1
Rényi, AL; Ross, SB	1
Shulgin, AT	1
Ding, XZ; Mocchetti, I	1
Abraham, P; Boja, JW; Carroll, FI; Kopajtic, TA; Kuhar, MJ; Lewin, AH; Mitchell, WM; Patel, A	1
Baldessarini, RJ; Kula, NS	1
Rothman, RB	1
Kruk, ZL; Millar, J; Stamford, JA	1
Dougan, DF; Duffield, P; Wade, DN	1
Baldessarini, RJ; Vogt, M	1
Byrd, LD; Church, WH; Justice, JB	1
Cho, AK; Howard, BD; Koide, M	1
Carmichael, FJ; Israel, Y	1
Scheel-Krüger, J	1
Cubeddu, LX; Hoffmann, IS; James, MK	1
Kruk, ZL; Wieczorek, WJ	1
Meiergerd, SM; Schenk, JO	1
Gatley, SJ	1
Alexoff, DL; Fowler, JS; Gatley, SJ; King, P; Schlyer, DJ; Shea, C; Wolf, AP	1
Acri, JB; Siedleck, BK; Witkin, JM	1
Agoston, GE; Newman, AH	1
Berger, SP; Fox, LM; Ho, LB; Hsu, K; Katz, JL; Newman, AH; Tolliver, BK	1
Agoston, GE; Alling, KL; Forster, MJ; Katz, JL; Kline, RH; Kopajtic, TA; Newman, AH; Woolverton, WL	1
Agoston, GE; Hecht, GS; Katz, JL; Newman, AH; Woolverton, WL	1
Berfield, JL; Ferrer, JV; Javitch, JA; Reith, ME; Wang, LC	1
Justice, JB; Katz, JL; Kopajtic, T; Newman, AH; Wirtz, S; Zou, MF	1
Cao, J; Eddington, ND; Gao, H; Newman, AH; Raje, S	1
Agoston, GE; Katz, JL; Kopajtic, TA; Newman, AH	1
Chen, N; Reith, ME; Zhen, J	1
Ebbs, A; Katz, JL; Newman, AH; Tanda, G	1
Desai, RI; Katz, JL; Koffarnus, M; Kopajtic, TA; Newman, AH	1
Katz, JL; Li, SM; Newman, AH	1
Cao, J; Cornish, J; Eddington, ND; Katz, JL; Newman, AH; Raje, S	2
Bondi, CD; Kozikowski, AP; Kulkarni, SS; Newman, AH; Pan, S; Surratt, CK; Ukairo, OT	1
Desai, RI; French, D; Katz, JL; Kopajtic, TA; Newman, AH	1
Campbell, VC; Katz, JL; Kopajtic, TA; Newman, AH	1
Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH	1
Erös-Sarnyai, M; Looby, AR; Lukas, SE; Lundahl, LH; McNeil, JF; Penetar, DM; Su, Z	1
Ramanujapuram, S; Surratt, CK; Ukairo, OT	1
Campbell, BL; Ebbs, AL; Elias, LM; Katz, JL; Kopajtic, TA; Newman, AH; Tanda, G	1
Eddington, ND; Newman, AH; Othman, AA	1
Blakely, RD; Henry, LK	1
Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J	1
Hiranita, T; Katz, JL; Newman, AH; Soto, PL	1
Ebbs, AL; Green, JL; Katz, JL; Newman, AH; Tallarida, RJ; Tanda, G; Tronci, V	1
Canales, JJ; Cardá, M; Ferragud, A; Hernández-Rabaza, V; Merino, V; Murga, J; Nácher, A; Velázquez-Sánchez, C	2
Canales, JJ; Cardá, M; Ferragud, A; Murga, J; Velázquez-Sánchez, C	1
Beuming, T; Bisgaard, H; Gether, U; Larsen, MA; Loland, CJ; Mazier, S; Newman, AH; Shi, L; Weinstein, H	1
Donovan, DM; Katz, JL; Kopajtic, TA; Liu, Y; Newman, AH; Surratt, CK	1
Agoston, GE; Cao, J; Katz, JL; Kopajtic, TA; Li, SM; Newman, AH; O'Callaghan, MJ	1
Desai, A; Fraser, R; Gnegy, ME; Guptaroy, B; Zhang, M	1
España, RA; Ferris, MJ; Harp, J; Jones, SR; Oleson, EB	1
Canales, JJ; Ferragud, A; García-Sevilla, JA; Ramos-Miguel, A; Velázquez-Sánchez, C	1
Ali, S; Davis, FA; Gaddiraju, NV; Hashim, A; Mehrotra, S; Murray, TF; Reith, ME; Schmitt, KC; Sershen, H; Sheikh, IS; Theddu, N; Unterwald, EM	1
Hayashi, S; Hiranita, T; Katz, JL; Li, L; Newman, AH	1
Chun, LE; Ebbs, AL; Green, JL; Katz, JL; Kopajtic, TA; Li, SM; Mereu, M; Newman, AH; Tanda, G; Thomas, AM; Tronci, V; Zou, MF	1
Desai, RI; Grandy, DK; Katz, JL; Lupica, CR	1
Baumann, MH; Blough, BE; Hong, WC; Jones, KT; Katz, JL; Partilla, JS; Reith, ME; Rothman, RB; Schmitt, KC	1
Desai, RI; Katz, JL; Slezak, JM	1
Avelar, AJ; Beckstead, MJ; Cao, J; Newman, AH	1
Jean, B; Madura, JD; Surratt, CK	1
Henry, LK; Krout, D; Lever, JR; Newman, AH; Pramod, AB; Tomlinson, MJ; Vaughan, RA	1

Reviews

2 review(s) available for cocaine and benztropine

Article	Year
Novel benztropine [3a-(diphenylmethoxy)tropane] analogs as probes for the dopamine transporter. Current medicinal chemistry, 1998, Volume: 5, Issue:4 Topics: Benztropine; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders	1998
Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter. Drug and alcohol dependence, 2015, Feb-01, Volume: 147 Topics: Animals; Benzhydryl Compounds; Benztropine; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Delivery Systems; Humans; Ligands; Modafinil; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary	2015

Article

Year

Novel benztropine [3a-(diphenylmethoxy)tropane] analogs as probes for the dopamine transporter.

Current medicinal chemistry, 1998, Volume: 5, Issue:4

Topics: Benztropine; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders

1998

Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter.

Drug and alcohol dependence, 2015, Feb-01, Volume: 147

Topics: Animals; Benzhydryl Compounds; Benztropine; Central Nervous System Stimulants; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Delivery Systems; Humans; Ligands; Modafinil; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary

2015

Trials

1 trial(s) available for cocaine and benztropine

Article	Year
Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers. Human psychopharmacology, 2006, Volume: 21, Issue:8 Topics: Adult; Benztropine; Blood Pressure; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Electrocardiography; Euphoria; Heart Rate; Humans; Infusions, Intravenous; Linear Models; Male; Muscarinic Antagonists; Pupil; Skin Temperature	2006

Article

Year

Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers.

Human psychopharmacology, 2006, Volume: 21, Issue:8

Topics: Adult; Benztropine; Blood Pressure; Cocaine; Cocaine-Related Disorders; Data Interpretation, Statistical; Electrocardiography; Euphoria; Heart Rate; Humans; Infusions, Intravenous; Linear Models; Male; Muscarinic Antagonists; Pupil; Skin Temperature

2006

Other Studies

73 other study(ies) available for cocaine and benztropine

Article	Year
Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20 Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes	1995
Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles. Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15 Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Dopamine Antagonists; Mice; Rats; Structure-Activity Relationship; Tropanes	1994
3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile. Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6 Topics: Animals; Benztropine; Binding, Competitive; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Neostriatum; Nerve Tissue Proteins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Tropanes	1997
Effects of two-carbon bridge region methoxylation of benztropine: discovery of novel chiral ligands for the dopamine transporter. Bioorganic & medicinal chemistry letters, 2001, Mar-26, Volume: 11, Issue:6 Topics: Benztropine; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Conformation; Muscarinic Antagonists; Nerve Tissue Proteins; Structure-Activity Relationship	2001
Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors. Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8 Topics: Animals; Bridged Bicyclo Compounds; Carrier Proteins; Cerebral Cortex; Cocaine-Related Disorders; Corpus Striatum; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Octanes; Protein Binding; Radioligand Assay; Rats; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Synaptosomes	2003
Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody. Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1 Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay	2004
Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter. Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: Animals; Benztropine; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Conformation; Nerve Endings; Nerve Tissue Proteins; Putamen; Radioligand Assay; Rats; Stereoisomerism; Structure-Activity Relationship; Tropanes	2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
3D-QSAR study of 8-azabicyclo[3.2.1] octane analogs antagonists of cholinergic receptor. Bioorganic & medicinal chemistry letters, 2009, Jun-01, Volume: 19, Issue:11 Topics: Cholinergic Antagonists; Computer Simulation; Models, Chemical; Quantitative Structure-Activity Relationship; Receptors, Cholinergic; Tropanes	2009
Effects of dopaminergic agonists and antagonists of feeding in intact and 6-hydroxydopamine-treated rats. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:2 Topics: Animals; Apomorphine; Benztropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; Cocaine; Dextroamphetamine; Dopamine; Dopamine Antagonists; Eating; Hydroxydopamines; Levodopa; Male; Methylphenidate; Methyltyrosines; Motor Activity; Rats; Spiperone; Telencephalon	1977
Potentiation by cocaine of the stimulus-induced increase in dopamine synthesis in rat brain striatal synaptosomes. Neuropharmacology, 1977, Volume: 16, Issue:5 Topics: Animals; Benztropine; Brain; Cocaine; Dopamine; Drug Synergism; In Vitro Techniques; Male; Rats; Tyrosine; Veratridine; Veratrine	1977
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain. Life sciences, 1977, May-15, Volume: 20, Issue:10 Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan	1977
Methylphenidate-like effects of the new antidepressant drug nomifensine (HOE 984). European journal of pharmacology, 1976, Volume: 38, Issue:2 Topics: Animals; Antidepressive Agents; Apomorphine; Benztropine; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Isoquinolines; Male; Methylphenidate; Rats; Reserpine; Stereotyped Behavior; Synaptosomes; Time Factors	1976
Inhibition of the uptake of 3-H-dopamine and 14-C-5-hydroxytryptamine in mouse striatum slices. Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:1 Topics: Amphetamine; Animals; Benztropine; Carbon Radioisotopes; Cocaine; Corpus Striatum; Depression, Chemical; Dopamine; In Vitro Techniques; Male; Mice; Rats; Serotonin; Stereoisomerism; Tritium	1975
Drugs of abuse in the future. Clinical toxicology, 1975, Volume: 8, Issue:4 Topics: Amphetamines; Barbiturates; Benzodiazepines; Benztropine; Cocaine; Drug and Narcotic Control; Forecasting; Hallucinogens; Humans; Morphinans; Morphine Derivatives; Nonprescription Drugs; Phencyclidine; Substance-Related Disorders; United States	1975
Dopaminergic regulation of cholecystokinin mRNA content in rat striatum. Brain research. Molecular brain research, 1992, Volume: 12, Issue:1-3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benztropine; Blotting, Northern; Brain; Cerebral Cortex; Cholecystokinin; Cocaine; Corpus Striatum; Dopamine; Haloperidol; Kinetics; Male; Mesencephalon; Organ Specificity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; RNA, Messenger	1992
High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain. Synapse (New York, N.Y.), 1992, Volume: 12, Issue:1 Topics: Animals; Autoradiography; Benztropine; Binding, Competitive; Brain; Carrier Proteins; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Iodine Radioisotopes; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tritium	1992
Lack of increase in dopamine transporter binding or function in rat brain tissue after treatment with blockers of neuronal uptake of dopamine. Neuropharmacology, 1991, Volume: 30, Issue:1 Topics: Animals; Benztropine; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Kinetics; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Reference Values	1991
High affinity dopamine reuptake inhibitors as potential cocaine antagonists: a strategy for drug development. Life sciences, 1990, Volume: 46, Issue:20 Topics: Benztropine; Bupropion; Cocaine; Dopamine; Drug Evaluation, Preclinical; Humans; Mazindol; Nomifensine; Propiophenones; Substance-Related Disorders	1990
Dissociation of the actions of uptake blockers upon dopamine overflow and uptake in the rat nucleus accumbens: in vivo voltammetric data. Neuropharmacology, 1989, Volume: 28, Issue:12 Topics: Animals; Benztropine; Bupropion; Cocaine; Dopamine; Electric Stimulation; Electrochemistry; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei	1989
Modulation of dopamine receptors in the Tapes clam by dextroamphetamine and phenylethanolamine. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:2 Topics: Adenosine Monophosphate; Amantadine; Animals; Benztropine; Bivalvia; Chlorphenamidine; Clozapine; Cocaine; Dextroamphetamine; Dopamine; Ethanolamines; Heart Rate; Myocardial Contraction; Receptors, Dopamine; Serotonin; Tetrahydronaphthalenes	1987
Release of 3H-dopamine and analogous monoamines from rat striatal tissue. Cellular and molecular neurobiology, 1988, Volume: 8, Issue:2 Topics: Amines; Animals; Benztropine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Male; Norepinephrine; p-Hydroxyamphetamine; Rats; Rats, Inbred Strains; Subcellular Fractions; Veratridine	1988
Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine. European journal of pharmacology, 1987, Jul-23, Volume: 139, Issue:3 Topics: Animals; Benztropine; Cocaine; Corpus Striatum; Dopamine; Extracellular Space; Male; Nomifensine; Rats; Rats, Inbred Strains; Time Factors; Tropanes	1987
Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. Journal of neurochemistry, 1986, Volume: 47, Issue:4 Topics: Adrenal Gland Neoplasms; Animals; Benztropine; Binding, Competitive; Biological Transport; Carrier Proteins; Catecholamine Plasma Membrane Transport Proteins; Cell Line; Cocaine; Desipramine; Dopamine; Kinetics; Membrane Transport Proteins; Molecular Weight; Nitrogen Mustard Compounds; Norepinephrine; Pheochromocytoma; Proteins; Rats; Sodium	1986
In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:2 Topics: Animals; Atropine; Benztropine; Brain; Chlorpromazine; Cocaine; Codeine; Desipramine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Levorphanol; Lipids; Meperidine; Methadone; Mice; Morphine; Naloxone; Narcotics; Norepinephrine; Solubility; Synaptosomes; Tritium	1973
Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugs. European journal of pharmacology, 1972, Volume: 18, Issue:1 Topics: Amphetamine; Animals; Antidepressive Agents; Behavior, Animal; Benztropine; Brain; Brain Chemistry; Cocaine; Desipramine; Dopamine; Imipramine; Iproniazid; Male; Motor Activity; Nialamide; Norepinephrine; Normetanephrine; Parasympatholytics; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tropanes; Tyramine	1972
Frequency-dependent effects of neuronal uptake inhibitors on the autoreceptor-mediated modulation of dopamine and acetylcholine release from the rabbit striatum. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1 Topics: Acetylcholine; Animals; Apomorphine; Benztropine; Bupropion; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Neurons; Nomifensine; Propiophenones; Rabbits; Sulpiride	1983
A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice. Brain research, 1994, Sep-19, Volume: 657, Issue:1-2 Topics: Animals; Benztropine; Brain; Caudate Nucleus; Cocaine; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Nomifensine; Nucleus Accumbens; Putamen; Rats; Rats, Wistar; Sulpiride	1994
Kinetic evaluation of the commonality between the site(s) of action of cocaine and some other structurally similar and dissimilar inhibitors of the striatal transporter for dopamine. Journal of neurochemistry, 1994, Volume: 63, Issue:5 Topics: Animals; Benztropine; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Male; Mazindol; Models, Biological; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley	1994
Estimation of upper limits on human radiation absorbed doses from carbon-11-labeled compounds. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:12 Topics: Animals; Benztropine; Carbon Radioisotopes; Cocaine; Deoxyglucose; Dogs; Humans; Mice; Models, Biological; Papio; Putrescine; Radiation Dosage; Selegiline; Spiperone; Tissue Distribution	1993
Plasma input function determination for PET using a commercial laboratory robot. Nuclear medicine and biology, 1995, Volume: 22, Issue:7 Topics: Animals; Benztropine; Blood Chemical Analysis; Carbon Radioisotopes; Cocaine; Fluorobenzenes; Humans; Methylphenidate; Papio; Phenols; Radioisotopes; Reproducibility of Results; Robotics; Selegiline; Tomography, Emission-Computed	1995
Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1 Topics: Animals; Atropine; Behavior, Animal; Benztropine; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Male; Mice; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Seizures	1996
Behavioral and neurochemical effects of the dopamine transporter ligand 4-chlorobenztropine alone and in combination with cocaine in vivo. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1 Topics: Animals; Behavior, Animal; Benztropine; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Discrimination Learning; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Antagonism; Injections, Intraperitoneal; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Microinjections; Motor Activity; Nerve Tissue Proteins; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	1999
Dopamine transporter binding without cocaine-like behavioral effects: synthesis and evaluation of benztropine analogs alone and in combination with cocaine in rodents. Psychopharmacology, 2001, Volume: 154, Issue:4 Topics: Animals; Antiparkinson Agents; Benztropine; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Muscarinic M1; Receptors, Muscarinic; Serotonin Plasma Membrane Transport Proteins; Symporters	2001
Further studies of the reinforcing effects of benztropine analogs in rhesus monkeys. Psychopharmacology, 2001, Volume: 154, Issue:4 Topics: Animals; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Female; Macaca mulatta; Male; Piperazines; Reaction Time; Reinforcement Schedule; Self Administration	2001
The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter. The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31 Topics: Benztropine; Binding Sites; Binding, Competitive; Carrier Proteins; Cell Membrane; Cocaine; Cysteine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Indicators and Reagents; Kinetics; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mesylates; Models, Molecular; Nerve Tissue Proteins; Protein Conformation	2001
Novel tropane-based irreversible ligands for the dopamine transporter. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Animals; Azides; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; In Vitro Techniques; Isothiocyanates; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Putamen; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes	2001
Evaluation of the blood-brain barrier transport, population pharmacokinetics, and brain distribution of benztropine analogs and cocaine using in vitro and in vivo techniques. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:2 Topics: Animals; Benztropine; Biological Transport; Blood-Brain Barrier; Brain; Cattle; Cocaine; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vasoconstrictor Agents	2003
Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:2 Topics: Animals; Antiparkinson Agents; Benztropine; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley	2004
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine. Journal of neurochemistry, 2004, Volume: 89, Issue:4 Topics: Amino Acid Substitution; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Muscarinic Antagonists; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Piperazines; Protein Binding; Sodium; Structure-Activity Relationship; Zinc	2004
Effects of 4'-chloro-3 alpha-(diphenylmethoxy)-tropane on mesostriatal, mesocortical, and mesolimbic dopamine transmission: comparison with effects of cocaine. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:2 Topics: Animals; Benztropine; Cocaine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Limbic System; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley	2005
Identification of a dopamine transporter ligand that blocks the stimulant effects of cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Feb-23, Volume: 25, Issue:8 Topics: Animals; Benztropine; Central Nervous System Stimulants; Cerebellum; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Motor Activity; Nerve Tissue Proteins; Rats	2005
Place conditioning and locomotor effects of N-substituted, 4',4''-difluorobenztropine analogs in rats. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:3 Topics: Animals; Atropine; Benztropine; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1	2005
Pharmacodynamic assessment of the benztropine analogues AHN-1055 and AHN-2005 using intracerebral microdialysis to evaluate brain dopamine levels and pharmacokinetic/pharmacodynamic modeling. Pharmaceutical research, 2005, Volume: 22, Issue:4 Topics: Animals; Benztropine; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Fluid; Male; Microdialysis; Models, Biological; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	2005
Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2 Topics: Amino Acid Substitution; Animals; Aspartic Acid; Benztropine; Binding, Competitive; CHO Cells; Cocaine; Cricetinae; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Immunohistochemistry; Kinetics; Ligands; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Transfection	2005
Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1 Topics: Animals; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Piperazines	2005
Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2 Topics: Animals; Benztropine; Binding, Competitive; Brain; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Guanidines; Histamine; Histamine Agonists; Histamine H1 Antagonists; In Vitro Techniques; Male; Methylhistamines; Motor Activity; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Tropanes	2005
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands. Bioorganic & medicinal chemistry letters, 2005, Dec-15, Volume: 15, Issue:24 Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine	2005
Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis. Biopharmaceutics & drug disposition, 2006, Volume: 27, Issue:5 Topics: Animals; Benztropine; Brain; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Inhibitory Concentration 50; Male; Microdialysis; Rats; Rats, Sprague-Dawley	2006
Fluctuation of the dopamine uptake inhibition potency of cocaine, but not amphetamine, at mammalian cells expressing the dopamine transporter. Brain research, 2007, Feb-02, Volume: 1131, Issue:1 Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Benztropine; Binding, Competitive; Brain; Brain Chemistry; Cell Line, Tumor; Chlorocebus aethiops; CHO Cells; Cocaine; Cocaine-Related Disorders; COS Cells; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Mazindol; Methylphenidate; Neurons; Radioligand Assay	2007
Effects of muscarinic M1 receptor blockade on cocaine-induced elevations of brain dopamine levels and locomotor behavior in rats. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1 Topics: Animals; Benztropine; Brain Chemistry; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Microdialysis; Motor Activity; Muscarinic Antagonists; Nucleus Accumbens; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Stereotyped Behavior; Synaptic Transmission	2007
Applicability of the dopamine and rate hypotheses in explaining the differences in behavioral pharmacology of the chloro-benztropine analogs: studies conducted using intracerebral microdialysis and population pharmacodynamic modeling. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2 Topics: Algorithms; Animals; Area Under Curve; Benztropine; Brain Chemistry; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microdialysis; Models, Biological; Molecular Structure; Nucleus Accumbens; Rats; Rats, Sprague-Dawley	2007
Distinctions between dopamine transporter antagonists could be just around the bend. Molecular pharmacology, 2008, Volume: 73, Issue:3 Topics: Animals; Benztropine; Carbazoles; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Mice; Models, Molecular; Motor Activity; Protein Conformation; Protein Structure, Secondary; Rats	2008
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties. Journal of neurochemistry, 2008, Volume: 107, Issue:4 Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan	2008
Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:2 Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration	2009
Combinations of cocaine with other dopamine uptake inhibitors: assessment of additivity. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:3 Topics: Animals; Benztropine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Microdialysis; Nucleus Accumbens	2009
The dopamine uptake inhibitor 3 alpha-[bis(4'-fluorophenyl)metoxy]-tropane reduces cocaine-induced early-gene expression, locomotor activity, and conditioned reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:12 Topics: Animals; Benztropine; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gene Expression; Male; Mice; Motor Activity; Nomifensine; Proto-Oncogene Proteins c-fos; Reward; Space Perception; Stereotyped Behavior	2009
A dopamine transport inhibitor with markedly low abuse liability suppresses cocaine self-administration in the rat. Psychopharmacology, 2009, Volume: 207, Issue:2 Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Long-Evans; Reinforcement Schedule; Reward; Self Administration; Sucrose	2009
The high affinity dopamine uptake inhibitor, JHW 007, blocks cocaine-induced reward, locomotor stimulation and sensitization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:7 Topics: Analysis of Variance; Animals; Behavior, Animal; Benztropine; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Male; Maze Learning; Mice; Motor Activity; Reward	2010
The binding sites for benztropines and dopamine in the dopamine transporter overlap. Neuropharmacology, 2011, Volume: 60, Issue:1 Topics: Animals; Benztropine; Binding Sites; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Models, Molecular; Structure-Activity Relationship	2011
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3 Topics: Adrenergic Uptake Inhibitors; Animals; Benztropine; Binding, Competitive; Cell Line, Tumor; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Mice; Mice, 129 Strain; Mice, Inbred Strains; Mice, Knockout; Neuroblastoma; Piperazines; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Selective Serotonin Reuptake Inhibitors; Sodium; Triprolidine	2010
N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:2 Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Conditioning, Psychological; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Guinea Pigs; Ligands; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Self Administration	2011
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters. Molecular pharmacology, 2011, Volume: 79, Issue:3 Topics: Amphetamine; Benztropine; Binding Sites; Biotinylation; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Fluoxetine; HEK293 Cells; Humans; Immunoblotting; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Pharmacokinetics; Protein Conformation	2011
Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3 Topics: Animals; Behavior, Animal; Benztropine; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Exploratory Behavior; Histamine H1 Antagonists; Illicit Drugs; Kinetics; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nucleus Accumbens; Piperidines; Psychomotor Agitation; Reward; Spatial Behavior	2012
Substituting a long-acting dopamine uptake inhibitor for cocaine prevents relapse to cocaine seeking. Addiction biology, 2013, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Behavior, Addictive; Benztropine; Blotting, Western; Brain-Derived Neurotrophic Factor; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Fas-Associated Death Domain Protein; Humans; Male; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Reinforcement Schedule; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome	2013
Novel C-1 substituted cocaine analogs unlike cocaine or benztropine. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:2 Topics: Animals; Benztropine; Brain; Cocaine; Conditioning, Operant; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Indicators and Reagents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neocortex; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Pregnancy; Protein Binding; Protein Conformation; Radioligand Assay; Serotonin Plasma Membrane Transport Proteins; Sodium; Sodium Channels; Structure-Activity Relationship; Swimming; Veratridine	2012
The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration. Psychopharmacology, 2013, Volume: 225, Issue:3 Topics: Animals; Benztropine; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug Interactions; Food; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Stereotyped Behavior	2013
Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change. Psychopharmacology, 2013, Volume: 229, Issue:2 Topics: Analysis of Variance; Animals; Benztropine; Binding Sites; Cocaine; Conditioning, Operant; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microdialysis; Nucleus Accumbens; Protein Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Time Factors	2013
Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:1 Topics: Animals; Benztropine; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Female; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity	2014
Further delineation between typical and atypical dopamine uptake inhibitors: effects on food-maintained behavior and food consumption. Behavioural pharmacology, 2017, Volume: 28, Issue:1 Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule	2017
Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons. Neuropharmacology, 2017, Sep-01, Volume: 123 Topics: Action Potentials; Animals; Autoreceptors; Benzhydryl Compounds; Benztropine; Cocaine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Male; Mesencephalon; Mice, Inbred DBA; Modafinil; Patch-Clamp Techniques; Receptors, Dopamine D2; Synaptic Transmission; Tissue Culture Techniques	2017
Molecular dynamics of conformation-specific dopamine transporter-inhibitor complexes. Journal of molecular graphics & modelling, 2017, Volume: 76 Topics: Animals; Benztropine; Binding Sites; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Molecular Dynamics Simulation; Protein Binding; Protein Conformation	2017
Identification of the benztropine analog [ Neurochemistry international, 2019, Volume: 123 Topics: Benztropine; Binding Sites; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Iodine Radioisotopes; Structure-Activity Relationship	2019