cocaine has been researched along with benzoylecgonine in 693 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (8.37) | 18.7374 |
| 1990's | 241 (34.78) | 18.2507 |
| 2000's | 188 (27.13) | 29.6817 |
| 2010's | 182 (26.26) | 24.3611 |
| 2020's | 24 (3.46) | 2.80 |
| Authors | Studies |
|---|---|
| Bloch, R; Misra, AL; Mulé, SJ; Nayak, PK | 1 |
| Budd, RD; Chinn, DM; Jain, NC; Leung, WJ; Sneath, TS | 1 |
| De Pace, A; Jukofsky, D; Kogan, M; Mulé, SJ; Verebey, K | 1 |
| Hamilton, HE; Harris, SC; Wallace, JE | 1 |
| DePace, AC; Kogan, MJ; Mulé, SJ; Resnick, RB; Verebey, KG | 1 |
| Adams, SM; Lewand, DL; Mueller, MA; Wang, RI | 1 |
| Blum, K; Hamilton, HE; King, DE; McNay, JL; Schwertner, H; Wallace, JE | 1 |
| Bason, DJ; Hamilton, HE; Harris, SC; King, DE; Schwertner, HA; Wallace, JE | 1 |
| Clarkson, CW; Crumb, WJ | 1 |
| Rivier, C; Torres, G | 1 |
| Doerr, JK; Konkol, RJ; Madden, JA | 1 |
| Brown, JR; Kavanagh, KT; Maijub, AG | 1 |
| Aks, SE; Hryhorczuk, DO; Negrusz, A; Tebbett, I; Vander Hoek, TL | 1 |
| Barbieri, EJ; DiGregorio, GJ; Ferko, AP; Ruch, EK | 2 |
| Bosron, WF; Dean, RA; Dumaual, N; Harper, ET; Stoeckel, DA | 1 |
| Kikura, R; Nakahara, Y; Ochiai, T | 1 |
| Browne, S; Jain, L; Meyer, W; Moore, C; Negrusz, A; Tebbett, I | 1 |
| Cañez, MS; King, TS; Luther, MF; Samuels, MH; Schenken, RS | 1 |
| Akiyama, S; Kuroda, N; Nakashima, K; Okamoto, M; Yamaguchi, M; Yoshida, K | 1 |
| Fuller, B; Hickman, RM; James, MF; Janicki, P; Kambam, J; Kirsch, RE; Mets, B | 1 |
| de Zeeuw, RA; Ensing, JG; Racamy, C | 1 |
| Larsen, AK; Tebbett, IR | 1 |
| Lord, WD; Nolte, KB; Pinder, RD | 1 |
| Le, SD; Lovas, JJ; Taylor, RW; Ting, E; Vidal, D | 1 |
| Brogan, WC; Glamann, DB; Hillis, LD; Lange, RA | 1 |
| Fowler, JS; MacGregor, RR; Wolf, AP | 1 |
| Forman, R; Graham, K; Greenwald, M; Klein, J; Koren, G; Schneiderman, J | 1 |
| Kaufmann, RA; Moghissi, KS; Savoy-Moore, RT; Subramanian, MG | 1 |
| Otto, RA; Reichman, OS | 1 |
| Armant, DR; Kaufmann, RA | 1 |
| Kauffman, RE; Knazik, SR; Meert, KL; Rosenberg, NM; Yee, H | 1 |
| Olsen, GD; Sandberg, JA | 3 |
| Baselt, RC; Chang, JY; Yoshikawa, DM | 1 |
| Browne, SP; Logan, BK; Moore, CM; Scheurer, J; Tebbett, IR | 1 |
| Chan, MK; Gingras, JL; Klemka-Walden, LM; Weese-Mayer, DE | 1 |
| DeVane, CL; Miller, RL | 1 |
| Hearn, WL; Hime, G; Keran, EE; Wei, HA | 1 |
| Batki, SL; Dumontet, R; Jacob, P; Jones, RT; Manfredi, LB; Sorensen, JL | 1 |
| Clatterbaugh, HE; Frankenfield-Chernicoff, M; Schutzman, DL; Singer, J | 1 |
| Bosron, WF; Christian, CD; Dean, RA; Sample, RH | 1 |
| Hall, J; Muto, J; Rogers, C | 1 |
| Reuschel, SA; Smith, FP | 1 |
| Hook, EW; Neumann, TM; Reichart, CA; Zenilman, JM | 1 |
| Gowitt, GT; Hanzlick, R | 1 |
| Aufderhide, A; Cartmell, LW; Weems, C | 1 |
| Burnett, D; Richens, A; Smith, BL; Toseland, PA; Walker, G; Williams, J; Wilson, JF | 1 |
| Barr, WH; Boni, JP; Martin, BR | 1 |
| Cruz, OA; King, JW; Patrinely, JR; Reyna, GS | 1 |
| Falk, JL; Lau, CE; Ma, F | 2 |
| Camí, J; de la Torre, R; Ortuño, J; Segura, J | 1 |
| Javors, MA; Kang, IS; King, TS; Riehl, RM; Schenken, RS | 1 |
| Dow-Edwards, D | 1 |
| Burke, WM; Dhopesh, V; Maany, I; Ravi, NV; Vandegrift, B | 1 |
| Altieri, M; Bogema, S; Schwartz, RH | 1 |
| Madden, JA; Powers, RH | 1 |
| McKelway, R; Vieweg, V; Westerman, P | 1 |
| Logan, BK; Stafford, DT | 1 |
| Aderjan, R; Bogusz, M; Nadler, E; Neureither, B; Schmitt, G | 1 |
| Fitzmaurice, LS; Fox, M; Knapp, JF; Roberts, DK; Waeckerle, JF; Wasserman, GS | 1 |
| Bodor, G; Roggeman, R; Turk, J | 1 |
| Alberti, X; Baud, F; Diamant-Berger, O; Gherardi, R; Marc, B | 1 |
| Borondo, JC; Candenas, I; Garfia, A; Lucena, J; Valverde, JL | 1 |
| Weddington, WW | 1 |
| Moore, FM; Simpson, D | 1 |
| Ash, KO; Pearson, SD; Urry, FM | 1 |
| Frambes, NA; Kirstein, CL; Spear, LP | 2 |
| Ballatore, A; Caprioli, RM; Seifert, WE | 1 |
| Callahan, LS; McCurdy, HH; Williams, RD | 1 |
| Graham, K; Greenwald, M; Klein, J; Koren, G; Schneiderman, J | 1 |
| Lampert, BM; Stewart, JT | 1 |
| Abel, EL | 1 |
| DePace, A; Verebey, K | 1 |
| Bogema, S; Schwartz, RH; Thorne, MM | 1 |
| Durkin, MM; Kogan, MJ; Pierson, DJ; Willson, NJ | 1 |
| Burke, WM; Dhopesh, V; Maany, I; McLellan, AT; Ravi, NV; Vandegrift, B | 1 |
| Goff, ML; Goodbrod, JR; Omori, AI | 1 |
| Bralliar, BB; Owens, JB; Skarf, B | 1 |
| Chasnoff, IJ; Griffith, DR; Lewis, DE; Willey, S | 1 |
| Cone, EJ | 3 |
| Lacouture, PG; Roa, J; Shannon, M; Woolf, A | 1 |
| de Kanel, J; Dunlap, L; Hall, TD | 1 |
| Ng, PS; Ou, DW; Papa, VM; Robbins, EF | 1 |
| Baud, FJ; Diamant-Berger, O; Dupeyron, JP; Gherardi, RK; Leporc, P; Marc, B | 1 |
| Cone, EJ; Mell, LD; Menchen, SL; Mitchell, J; Paul, BD | 1 |
| Cone, EJ; Mitchell, J | 1 |
| Chuntharapai, A; Jones, R; Seaman, W; Stesin, A; Van Dyke, C | 1 |
| Balabanova, S; Brunner, H; Homoki, J; Wolf, HU | 1 |
| Gawin, FH; Weiss, RD | 1 |
| McCartney, QW; Tebbett, IR | 1 |
| Palatý, V | 1 |
| Chouteau, M; Leppert, P; Namerow, PB | 1 |
| Cone, EJ; Menchen, SL; Mitchell, J | 1 |
| Colbert, DL; Landon, J; Sidki, AM; Smith, DS | 1 |
| Bailey, DN | 3 |
| Benowitz, NL; Elias-Baker, BA; Jacob, P; Jones, RT | 1 |
| Balabanova, S; Brunner, H; Nowak, R | 1 |
| Liu, RH; Smith, FP | 1 |
| Byers, JM; Froede, RC; Henry, TE; Jones, AM; Rogers, JN | 1 |
| Michalodimitrakis, M | 1 |
| Davis, GJ; Howard, RE; Hueter, DC | 1 |
| Reed, D; Spiehler, VR | 1 |
| Robinson, K; Smith, RN | 1 |
| Budd, RD | 1 |
| Khan, I; Novák, M; Salemink, CA | 1 |
| Fukui, Y; Kagawa, M; Matsubara, K | 1 |
| Fukui, Y; Maseda, C; Matsubara, K | 1 |
| Froldi, R; Gambaro, V; Mariani, R; Pisoni, F; Procaccianti, P | 1 |
| Budd, RD; Griesemer, EC; Liu, Y; Noguchi, TT; Raftogianis, L | 1 |
| Garrett, ER; Seyda, K | 1 |
| Budd, RD; Griesemer, EC; Liu, Y | 1 |
| Fletcher, SM; Hancock, VS | 1 |
| Budd, RD; Mathis, DF; Yang, FC | 1 |
| Lewis, JH | 1 |
| Bosron, WF; Brzezinski, MR; Dean, RA; Zhang, J | 1 |
| Kauffman, RF; Marino, D; Meert, KL; Rosenberg, NM | 1 |
| Loughlin, KR; Zhang, H | 1 |
| Baum, I; Erzouki, HK; Goldberg, SR; Schindler, CW | 1 |
| Cornish, JW; Fudala, PJ; Maany, I; Neal, S; O'Brien, CP; Poole, SA; Volpicelli, P | 1 |
| McIntyre, MK; Roberts, DK; Salomone, JA; Watson, WA; Westdorp, EJ | 1 |
| Medina, AM; Moody, DE | 1 |
| Phillips, DL; Roberts, SM; Tebbett, IR | 1 |
| Murphey, LJ; Olsen, GD; Sandberg, JA | 1 |
| Dasgupta, A; Thompson, WC | 1 |
| Kauffman, RE; Marino, D; Meert, KL; Rosenberg, NM; Yee, H | 1 |
| Anis, NA; Devine, PJ; Eldefrawi, AT; Eldefrawi, ME; Kim, S; Wright, J | 1 |
| Cabral, H; Frank, DA; Mirochnick, M; Turner, A; Zuckerman, B | 1 |
| Roberts, DK; Watson, WA; Wilson, BD | 1 |
| Hartwell, N; Hirsch, CS; Iqbal, MI; Leon, AC; Marzuk, PM; Portera, L; Stajic, M; Tardiff, K | 1 |
| Carballo, DD; Falk, PM; Sabater, RT | 1 |
| Holsapple, MP; Jeong, TC; Jordan, SD; Matulka, RA; Yang, KH | 1 |
| Masten, S; Phillips, DL; Shiverick, KT; Tebbett, IR | 1 |
| Hartwell, N; Hirsch, CS; Leon, AC; Marzuk, PM; Portera, L; Stajić, M; Tardiff, K | 1 |
| Chan, KM; Moriya, F; Noguchi, TT; Parnassus, WN | 1 |
| Ibrahim, HM; Katikaneni, LP; McArthur, PD; Nesbitt, L; Sallee, FR; Sethuraman, G | 1 |
| Kintz, P; Mangin, P | 1 |
| Browne, S; Covert, R; Dusick, A; Moore, C; Negrusz, A; Tebbett, I | 1 |
| Bermejo Barrera, AM; Strano Rossi, S | 1 |
| Cone, EJ; Wang, WL | 1 |
| Heyser, CJ; Rajachandran, L; Spear, LP; Spear, NE | 1 |
| Alvarez, TA; Keller, PA; Konkol, RJ; Madden, JA | 1 |
| Jones, RT; Moore, D; Stillman, R; Walker, J; Welm, S | 1 |
| Goldberg, SR; Tella, SR | 1 |
| Levine, B; Ramcharitar, V; Smialek, JE | 1 |
| Hänseler, E; Keller, H | 1 |
| Barks, J; Einarson, T; Forman, R; Greenwald, M; Klein, J; Koren, G; Mehta, D | 1 |
| Badger, TM; Burge, LJ; Creer, MH; Karba, R; Nehus, C; Primozic, S; Scalzo, FM | 1 |
| Klein, J; Koren, G; Lewis, D; Papageorgiou, A; Potter, S; Stack, DM; Stott, W; Valiante, G; Zelazo, PR | 1 |
| Balíková, M; Vecerková, J | 1 |
| Chao, CR; Jamdar, S; Morishima, HO; Virag, L | 1 |
| De Giovanni, N; Strano Rossi, S | 1 |
| Fukui, M; Igarashi, K; Kasuya, F; Nakajima, K; Nishikawa, M; Tatsuno, M; Tsuchihashi, H | 1 |
| Franks, JJ; Hickman, R; Janicki, PK; Kambam, JR; Mets, B; van der Watt, M | 1 |
| Branch, CA; Knuepfer, MM | 1 |
| Leikin, JB; Lewis, DE; Moore, CM | 1 |
| Abraham, TL; Bosron, WF; Brzezinski, MR; Dean, RA; Stone, CL | 1 |
| Aldano, A; Barbieri, EJ; Chawla, H; DiGregorio, GJ; Ferko, AP; Keohane, D; Rosenstock, R; Ruch, EK | 1 |
| Bruns, AD; Jacobs, AJ; Zieske, LA | 1 |
| Allen, HM; Chinchilli, VM; Enters, EK; Guo, H; Jackson, GF; Maher, JR; McDowell, KP; Robinson, SE | 1 |
| Covert, RF; Madden, JA; Schreiber, MD; Torgerson, LJ | 1 |
| Airth-Kindree, W; Doot, M; Leonard, J; Martin, C | 1 |
| Leskawa, KC; Lin, Y | 1 |
| Covert, RF; Schreiber, MD; Tebbett, IR; Torgerson, LJ | 1 |
| Andollo, W; Hearn, WL; Hernandez, A | 1 |
| Gaikwad, A; Gómez-Hens, A; Pérez-Bendito, D | 1 |
| Crayton, JW; O'Connor, FL; Reid, RW | 1 |
| D'Antoni, T; Mahone, PR; Scott, K; Sleggs, G; Woods, JR | 1 |
| Ferrara, SD; Snenghi, R; Tedeschi, L | 1 |
| Costa, LG; Tan, XX | 1 |
| Dombrowski, MP; Gauvin, JM; Hayashi, RH; Hurd, WW | 1 |
| Chan, KM; Matthews, WS; Saxena, S; Wong, ET | 1 |
| Corburt, MR; Koves, EM | 1 |
| Feldman, MS; Hand, I; Kim, MH; Noble, L; Wingert, WE; Yoon, JJ | 1 |
| Dewey, SL; Fowler, JS; Gatley, SJ; MacGregor, RR; Martin, T; Schlyer, DJ; Shea, CE; Volkow, ND; Wolf, AP; Yu, DW | 1 |
| Barr, H; Brown, Z; Callahan, C; Grant, T; Streissguth, AP | 1 |
| Fey, P; Moeller, MR; Wennig, R | 1 |
| Aufderheide, AC; Buikstra, J; Cartmell, LW; Ho, J; Springfield, AC | 1 |
| Allgood, CC; Sniegoski, LT; Welch, MJ | 1 |
| Cone, EJ; Darwin, WD; Wang, WL | 1 |
| Linder, MW; Valdes, R; Wagener, RE | 1 |
| Eliopoulos, C; Forman, R; Klein, J; Koren, G | 1 |
| Kikura, R; Nakahara, Y | 1 |
| Derewlany, LO; Knie, B; Koren, G; Oskamp, M; Simone, C | 1 |
| Daelemans, R; Demedts, P; Malbrain, ML; Neels, H; Verbraeken, H; Vissers, K; Wauters, A | 1 |
| Past, MR; Romberg, RW | 1 |
| Jennison, TA; Jones, CW; Urry, FM; Wozniak, E | 1 |
| Bagasra, O; Pomerantz, RJ | 1 |
| Gerlits, J | 1 |
| Cone, EJ; Darwin, WD; Gorelick, DA; Hillsgrove, M; Kato, K; Weinhold, L | 1 |
| Bandstra, ES; Hearn, WL; Hime, GW; Steele, BW; Wu, NC | 1 |
| Abukhalaf, IK; Abusada, GM; Alford, DD; Ansari, NA; Manno, BR; Manno, JE; Pramanik, AK; Vinzon-Bautista, I | 1 |
| Jain, NC; Sneath, TC; Sreenivasam, RC | 1 |
| Bredehorst, R; Kusterbeck, AW; Ligler, FS; Rabbany, SY | 1 |
| Cremese, M; Forte, E; Hill, D; Ostheimer, D; Wu, AH | 1 |
| Bennett, BA; Clodfelter, JE; Hyde, CE; Pecora, JR | 1 |
| Batki, SL; Jacob, P; Jones, RT; Manfredi, LB | 1 |
| Beasley, W; Needleman, SB; Past, M; Porvaznik, M; Romberg, RW | 1 |
| Batlle, MA; Wilcox, WD | 1 |
| Berger, GE; Craig, PA; Schramm, W; Smith, RH | 1 |
| Kidwell, DA | 1 |
| Gauthier, D; Jain, L; Meyer, W; Moore, C; Tebbett, I; Vidyasagar, D | 1 |
| Konkol, RJ; Murphey, LJ; Olsen, GD | 1 |
| Bernstein, BA; Boctor, F; Cooke, E; Fishman, S; Lewis, SC; Longobucco, DB; Rosengren, SS | 1 |
| Konkol, RJ; Olsen, GD | 1 |
| Cardenas, S; Gallego, M; Valcarcel, M | 1 |
| Konkol, RJ; Kron, JE; Olsen, GD | 1 |
| Hale, MJ; Kusterbeck, AW; Ligler, FS; Whelan, JP; Yu, H | 1 |
| Dasgupta, A; Mahle, C; McLemore, J | 1 |
| Fieguth, A; Guenther, D; Hori, A; Stan, AC | 1 |
| Aoki, K; Kuroiwa, Y; Yoshida, T | 1 |
| Garcia, DC; Garcia, GC; Ostrea, EM; Romero, A | 1 |
| Chao, CR; Cooper, TB; Iso, A; Morishima, HO; Nakahara, K | 1 |
| Kranzler, HR; McLaughlin, L; Stone, J | 1 |
| Clauwaert, KM; De Leenheer, AP; Lambert, WE; Van Bocxlaer, JF | 3 |
| Batki, SL; Delucchi, K; Jones, RT; Washburn, AM | 1 |
| Jamdar, S; Mets, B; Virag, L | 1 |
| Hedaya, MA; Pan, WJ | 3 |
| Bost, JE; Eichhorn, EJ; Heesch, CM; Keffer, JH; Negus, BH; Snyder, RW | 1 |
| Aoki, K; Kuroiwa, Y; Shikama, Y; Yoshida, T | 1 |
| Chiang, CN; Hawks, RL; Li, SH; Marschke, CK; Tai, BC | 1 |
| Belfer, RA; Boenning, DA; Klein, BL; Soldin, SJ | 1 |
| Bertholf, RL; Phillips, DL; Tebbett, IR | 1 |
| Dreka, C; Paul, BD; Smith, ML; Summers, JL | 1 |
| Deitermann, D; Dempsey, D; Leikin, J; Lewis, D; Moore, C | 1 |
| Alburges, ME; Crouch, DJ; Moody, DE; Rollins, DE; Spanbauer, AC | 1 |
| Giorgi, SN; Meeker, JE | 1 |
| Cone, EJ; Darwin, WD; Hillsgrove, MJ; Holicky, B; Yousefnejad, D | 1 |
| Cirimele, V; Kintz, P; Mangin, P; Sengler, C | 1 |
| Hernandez, MR; Klimov, AD; Kravec, CV; Rouse, SL; Salamone, SJ; Subuhi, HS; Towt, J; Tsai, SC; Twarowska, B | 1 |
| Ashcraft, J; Eichhorn, EJ; Heesch, CM; Hernandez, JA; Steiner, M | 1 |
| Crayton, JW; Deakin, AG; Ivery, DM; O'Connor, FL; Reid, RW | 1 |
| Borg, L; Chou, JZ; Ho, A; Kreek, MJ; Peters, JE; Reid, K | 1 |
| Dombrowski, MP; Hurd, WW; Wang, FL | 1 |
| Wingert, WE | 1 |
| Carmichael, S; Klein, L; Lindsay, MK; Peterson, H; Risby, J; Williams, H | 1 |
| Caddy, B; Carvajal, R; Lora-Tamayo, C; Smith, FP; Tagliaro, F | 1 |
| Kidwell, DA; Smith, FP | 1 |
| Jurado, C; Menéndez, M; Repetto, M; Rodriguez-Vicente, C | 1 |
| Leikin, J; Lewis, D; Moore, C; Morrissey, P | 1 |
| Church, MW; Subramanian, MG | 1 |
| Casas, M; Pérez de los Cobos, J; Ribalta, E; Trujols, J | 1 |
| Wilkins, JN | 1 |
| Bornheim, LM; Kim, KY | 1 |
| Cone, EJ; Garside, D; Goldberger, BA; Preston, KL | 1 |
| Bresson, M; Rerat, C; Rop, PP; Ruiz, E; Sauvain, M; Viala, A | 1 |
| Lau, CE; Ma, F; Zhang, J | 1 |
| Batki, SL; Delucchi, KL; Jones, RT | 1 |
| Bratton, GR; Livermore, CL; Miller, DK; Nation, JR; Wellman, PJ | 1 |
| Cone, EJ; Preston, KL; Schuster, CR; Silverman, K | 1 |
| Bosron, WF; Brzezinski, MR; Dean, RA; Zachman, FM; Zhang, J | 1 |
| Anderson, KG; Garcea, M; Tebbett, IR; van Harren, F | 1 |
| Goldberger, BA; Jenkins, AJ | 1 |
| Aguila-Mansilla, N; Barnea, A; Ho, RH; Little, BB | 1 |
| Chen, YR; Clyde, C; Johnson, BA; Johnson, P; Lesser, J; Ruiz, P; Schmitz, J; Swann, AC | 1 |
| Baselt, RC; Coleman, DE | 1 |
| Klein, J; Koren, G; Ursitti, F | 1 |
| Chesler, SN; Morrison, JF; Selavka, CM; Yoo, WJ | 1 |
| Assayag, P; Besse, S; Delcayre, C; Janmot, C; Latour, C; Nahas, G; Robert, V; Swynghedauw, B | 1 |
| Ho, CH; Karch, SB; Stephens, B | 1 |
| Jones, RT | 1 |
| Botelho, C; Bristow, GM; Foltz, RL; Kuntz, DJ; Moody, DE; Reuschel, SA | 1 |
| Briglia, E; Gawad, Y; Hollander, JE; Levitt, MA; Wetli, CV; Young, GP | 1 |
| Breen, P; Gurley, BJ; Light, KE; Nyamweya, NN | 1 |
| Andres, RL; Larrabee, KD; Monga, M; Wong, SS | 1 |
| Clauwaert, KM; De Leenheer, AP; Esmans, EL; Lambert, WE; Lemière, F; Van Bocxlaer, JF; Van den Eeckhout, EG | 1 |
| Garside, D; Goldberger, BA; Hamilton, WF; Maples, WR; Ropero-Miller, JD | 1 |
| Berger, O; Chang, SL; Fiala, M; Gan, X; Graves, MC; Kermani, V; Ling, W; Newton, T; Zhang, L | 1 |
| Dubrovsky, T; ElSohly, MA; Salamone, SJ; Towt, J; Tsai, SC; Twarowska, B | 1 |
| Allemann, D; Caslavska, J; Thormann, W | 1 |
| Cooper, TB; Morishima, HO; Whittington, RA; Zhang, Y | 1 |
| Franck, J; Ho, A; Kreek, MJ; Quiñones-Jenab, V; Schlussman, SD | 1 |
| Cooper, TB; Iso, A; Morishima, HO; Whittington, RA | 1 |
| Azer, NL; Eldefrawi, ME; O'Connell, KP; Schwartz, RP; Valdes, JJ; Wright, J | 1 |
| Laizure, SC; Parker, RB; Song, N | 1 |
| Jenkins, AJ; Levine, B; Smialek, JE; Titus, J | 1 |
| Brodbelt, JS; Hall, BJ; Parikh, AR | 1 |
| Kolodgie, FD; Mergner, WJ; Virmani, R; Wilson, PS | 1 |
| Fitzgerald, RL; Herold, DA; Rivera, JD | 1 |
| Diaz, J; Jamdar, S; Mets, B | 1 |
| Bowman, BP; Davis, SL; Kuhn, CM; Little, PJ; Scheffler, NM; Thomas, BF; Vaughan, SR; Walker, QD | 1 |
| Evans, SM; Fischman, MW; Foltin, RW; Haney, M | 1 |
| Cone, EJ; Goldberger, BA; Huestis, MA; Preston, KL; Umbricht, A; Wong, CJ | 1 |
| Altieri, I; Pacifici, R; Pellegrini, M; Pichini, S; Zuccaro, P | 1 |
| Fish, S; Mirochnick, M; Vinci, RJ | 1 |
| Diaz, J; Jamdar, S; Mets, B; Soo, E | 1 |
| Darwin, D; Eldefrawi, M; Huestis, M; Nath, N; Wright, J | 1 |
| Brantley, MD | 1 |
| Cabral, H; Frank, DA; McCarten, KM; Mirochnick, M; Park, H; Robson, CD; Zuckerman, B | 1 |
| Christ, MJ; Fujiwara, N; Gries, DM; Iwamoto, LM; Moore, CM; Nakamura, KT | 1 |
| Cole, MJ; Estapé, ES; Jeanville, PM; Needham, SR | 1 |
| Chasin, AA; Mídio, AF | 1 |
| Allen, DL; Oliver, JS | 1 |
| Bowerman, DL; Jenkins, WW; Karch, SB; Levisky, JA | 1 |
| Blair, IA; Diaz, J; Mets, B; Pantuck, C; Singh, G; Soo, E | 1 |
| Adnane, J; Bontempo, FA; Heesch, CM; Ristich, J; Wagner, WR; Wilhelm, CR | 1 |
| Bailey, R; Creson, D; Grabowski, J; Rhoades, H; Schmitz, JM; Silverman, P; Stotts, A | 1 |
| Baudry, F; Douceron, H; Hassnaoui, S; Marc, B; Vaquero, P; Zerrouki, L | 1 |
| Norman, AB; Warner, A | 1 |
| Hirsch, M; Mahl, MA; Sugg, U | 1 |
| Diaz, J; Jamdar, SC; Mets, B; Pantuck, CB | 1 |
| Foltz, RL; Moody, DE; Spanbauer, AC; Walsh, SL | 1 |
| Erickson, TB; Maggiore, JA; Negrusz, A; Shah, SM; Williams, RH | 1 |
| Bourland, JA; Hatab, MM; Hayes, EF; Kelly, RC; Sweeney, SA | 1 |
| Alterman, AI; Cornish, J; Kampman, KM; O'Brien, CP; Volpicelli, JR | 1 |
| Garza, AG; Ma, OJ; Roberts, DK; Steele, MT; Watson, WA; Westdorp, EJ | 1 |
| Lagos, F; Perrotti, LI; Quiñones-Jenab, V; Russo, SJ | 1 |
| Antonilli, L; Grassi, MC; Nencini, P; Suriano, C | 1 |
| Dewey, SL; Mackler, SA; O'Brien, CP; Stromberg, MF; Volpicelli, JR | 1 |
| Klingmann, A; Mattern, R; Pötsch, L; Skopp, G | 1 |
| Lidow, MS; Song, ZM; Zhou, M | 1 |
| Cheever, ML; Moody, DE | 1 |
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| Andrenyak, DM; Crystal, RG; De, BP; Evans, SM; Foltin, RW; Hicks, MJ; Janda, KD; Kaminsky, SM; Koob, GF; Lepherd, ML; Moody, DE; Ricart Arbona, RJ; Rosenberg, JB | 1 |
| Alvear, E; Hitschfeld, A; Mardones, C; von Baer, D | 1 |
| Andreuccetti, G; De Carvalho, HB; De Oliveira, KC; Do Prado, NV; Gjerde, H; Leyton, V; Muñoz, DR; Sinagawa, DM; Yonamine, M | 1 |
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| Concheiro, M; Ellefsen, KN; Gorelick, DA; Huestis, MA; Pirard, S | 2 |
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| Castiglioni, S; Gracia-Lor, E; Parabiaghi, A; Riva, F; Rousis, NI; Senta, I; Zuccato, E | 1 |
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| Castiglioni, S; De Felice, B; Ferrario, C; Finizio, A; Parolini, M; Salgueiro-González, N; Tremolada, P | 1 |
| Atkinson, S; Bailey, MJ; Costa, C; de Puit, M; Ismail, M; Palitsin, V; Webb, R | 1 |
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| Bailey, M; Costa, C; de Puit, M; Ismail, M; Stevenson, D; Webb, R | 1 |
| de Voogt, P; Emke, E; Kolkman, A; Vughs, D | 1 |
| Edwards, QA; Garner-O'Neale, LD; Kulikov, SM; Metcalfe, CD; Sultana, T; Yargeau, V | 1 |
| Freni, F; Groppi, A; Moretti, M; Morini, L; Osculati, AMM; Tajana, L; Tomaciello, I; Vignali, C; Visonà, SD | 1 |
| Gross, A; Hallak, H; Rosenstock, M; Shemesh-Darvish, L; Shinar, D | 1 |
| Andreuccetti, G; Berg, T; Gjerde, H; Leyton, V; Takitane, J; Vindenes, V | 1 |
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| Claussen, K; Heltsley, R; Hild, C; Puet, BL; Schwope, DM | 1 |
| Pan, MR; Qiang, HS; Shen, BH; Xiang, P; Yan, H | 1 |
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| Biagioli, S; Boni, MR; Cecchini, G; Chiavola, A; Di Marcantonio, C; Frugis, A | 1 |
| Aranguren, M; Gorlelo, JC; Krumbiegel, F; Nagel, A; Poliansky, N; Pragst, F; Rubio, NC; Thurmann, D; Zytowski, E | 1 |
| Busardò, FP; Giorgetti, R; Gottardi, M; Pacifici, R; Pichini, S; Tini, A; Varì, MR; Volpe, AR | 1 |
| Cela, R; Da Silva, KM; Estévez-Danta, A; González-Mariño, I; Quintana, JB; Rodil, R; Sodré, FF | 1 |
| Antunes, MV; Bastiani, MF; Bulcão, R; da Silva, ACC; de Lima Feltraco Lizot, L; Hahn, RZ; Linden, R; Perassolo, MS | 1 |
| Flanagan, RJ; Hudson, S; Rab, E | 1 |
| Antunes, MV; Bastiani, MF; da Silva, ACC; Hahn, RZ; Linden, R; Lizot, LLF; Maurer, TF; Perassolo, MS | 1 |
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| Badu-Tawiah, AK; Durisek, GR; Jackson, S; Kouatli, Y; Swiner, DJ; Walsh, BK | 1 |
| Amundsen, EJ; Baz-Lomba, JA; de Voogt, P; Emke, E; Goulding, N; Hall, W; Hickman, M; Jones, HE; Kuijpers, W; O'Brien, JW; Reid, M; Tscharke, BJ | 1 |
| Alygizakis, NA; Andrés-Costa, MJ; Bade, R; Bannwarth, A; Barron, LP; Baz-Lomba, JA; Been, F; Benaglia, L; Berset, JD; Bijlsma, L; Bodík, I; Brenner, A; Brock, AL; Burgard, DA; Castiglioni, S; Castrignanò, E; Celma, A; Christophoridis, CE; Covaci, A; de Voogt, P; Delémont, O; Devault, DA; Dias, MJ; Emke, E; Esseiva, P; Fatta-Kassinos, D; Fedorova, G; Fytianos, K; Gerber, C; González-Mariño, I; Grabic, R; Gracia-Lor, E; Grüner, S; Gunnar, T; Hapeshi, E; Heath, E; Helm, B; Hernández, F; Kankaanpaa, A; Karolak, S; Kasprzyk-Hordern, B; Krizman-Matasic, I; Lai, FY; Lechowicz, W; Lopes, A; López de Alda, M; López-García, E; Löve, ASC; Mastroianni, N; McEneff, GL; Montes, R; Munro, K; Nefau, T; O'Brien, JW; Oberacher, H; Oertel, R; Olafsdottir, K; Ort, C; Picó, Y; Plósz, BG; Polesel, F; Postigo, C; Quintana, JB; Ramin, P; Reid, MJ; Rice, J; Rodil, R; Salgueiro-González, N; Schubert, S; Senta, I; Simões, SM; Sremacki, MM; Styszko, K; Terzic, S; Thomaidis, NS; Thomas, KV; Tscharke, BJ; Udrisard, R; van Nuijs, ALN; Yargeau, V; Zuccato, E | 1 |
| Ahrendt, AJ; Ball, WJ; Duke, NEC; Joachimiak, A; Kirley, TL; Norman, AB; Pokkuluri, PR; Schiffer, M; Tabaja, N; Tan, K; Wilton, R; Zhou, M | 1 |
| Cui, J; Liu, W; Shen, B; Shen, M; Wang, X; Xiang, P; Zhang, S; Zhuo, Y | 1 |
| Busardò, FP; Gottardi, M; Graziano, S; Malaca, S; Marchei, E; Pichini, S | 1 |
| Bailey, MJ; Bunch, J; Costa, C; Gibson, B; Hudson, M; Ismail, M; Jang, M; Palitsin, V; Webb, R | 1 |
| Borges, KB; Dos Santos, NA; Filho, JFA; Lacerda, V; Pelição, FS; Romão, W | 1 |
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| Cortez, FS; de Campos, BG; Fontes, MK; Lebre, DT; Maranho, LA; Moreno, BB; Nobre, CR; Pereira, CDS; Pusceddu, FH | 1 |
| Gamero, J; Huertas, T; Jurado, C; Salguero, M; Soriano, T | 1 |
| Abou El Hassan, M; Colantonio, D; Likhodii, S; Nassar, BA | 1 |
| Avcioglu, G; Bal, C; Kozaci, LD; Yalcin Sahiner, S; Yilmaz, FM; Yilmaz, G | 1 |
| Álvarez, FJ; García-Mingo, M; Gutiérrez-Abejón, E; Herrera-Gómez, F | 1 |
| Chen, X; Deng, X; Hou, S; Huang, Y; Qiu, T; Tong, J; Wang, J; Wu, Y; Zhang, Y | 1 |
| Bouvarel, T; Chendo, C; Delaunay, N; Pichon, V | 1 |
| Chen, X; Deng, X; Hou, S; Li, Q; Tong, J; Wang, J; Wu, Y; Xie, T; Yang, K; Yao, J; Yao, W; Zhang, Y | 1 |
| Correia, AT; de Oliveira, TMN; Guimarães, LL; Pisetta, AM; Roveri, V | 1 |
| Beretta, G; De Felice, B; De Pascalis, F; di Cesare, F; Manenti, R; Nasti, R; Parolini, M; Pavlovic, R | 1 |
| Correia, AT; Guimarães, LL; Roveri, V; Toma, W | 1 |
| Boersma, HH; Borra, LCP; Bosman, IJ; Elsinga, PH; Emaus, RA; Kloos, DP; Rijken, DJ; Touw, DJ; van der Hulst, R | 1 |
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12 review(s) available for cocaine and benzoylecgonine
| Article | Year |
|---|---|
Biological activity of the alkaloids of Erythroxylum coca and Erythroxylum novogranatense.
Topics: Alkaloids; Anesthetics; Animals; Cats; Chemical Phenomena; Chemistry; Coca; Cocaine; Drug and Narcotic Control; Mice; Plants, Medicinal; Pyrrolidines; Rabbits; Rats; Tropanes; United Nations | 1984 |
Analysis of the cocaine metabolite in the urine of patients and physicians during clinical use.
Topics: Administration, Intranasal; Anesthetics, Local; Chromatography, Gas; Cocaine; Gas Chromatography-Mass Spectrometry; Gloves, Surgical; Humans; Masks; Mass Screening; Narcotics; Occupational Exposure; Otorhinolaryngologic Diseases; Patients; Physicians; Substance-Related Disorders; Time Factors | 1994 |
Pulmonary edema in an infant following passive inhalation of free-base ("crack") cocaine.
Topics: Acute Disease; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Gas Analysis; Cocaine; Crack Cocaine; Diagnosis, Differential; Humans; Infant, Newborn; L-Lactate Dehydrogenase; Leukocyte Count; Male; Pulmonary Edema; Respiration, Artificial; Tobacco Smoke Pollution | 1993 |
Effects of ethanol on cocaine metabolism and disposition in the rat.
Topics: Animals; Cocaine; Drug Interactions; Ethanol; Humans; Oxidation-Reduction; Rats; Substance-Related Disorders | 1997 |
Pharmacokinetics of cocaine: considerations when assessing cocaine use by urinalysis.
Topics: Cocaine; Humans; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1997 |
Mechanisms of cocaine hydrolysis and metabolism in vitro and in vivo: a clarification.
Topics: Animals; Cocaine; Humans; Hydrolysis; Species Specificity | 2000 |
Criteria for the interpretation of cocaine levels in human biological samples and their relation to the cause of death.
Topics: Bile; Brain Chemistry; Cerebrospinal Fluid; Cocaine; Dopamine Uptake Inhibitors; Forensic Medicine; Hair; Humans; Poisoning; Vitreous Body | 2004 |
The fatal case of a cocaine body-stuffer and a literature review - towards evidence based management.
Topics: Cocaine; Crime; Dopamine Uptake Inhibitors; Evidence-Based Medicine; Female; Foreign Bodies; Forensic Medicine; Humans; Intestinal Mucosa; Intestine, Small; Middle Aged; Prisoners | 2007 |
Cocaine abuse: dermatologic manifestations and therapeutic approaches.
Topics: Adult; Animals; Cocaine; Cocaine-Related Disorders; Delusions; Female; Humans; Male; Paresthesia; Skin; Skin Diseases; Skin Diseases, Parasitic; Substance Abuse Detection; Tooth Diseases; Weight Loss | 2008 |
Antipsychotic drugs in cocaine dependence: a systematic review and meta-analysis.
Topics: Antipsychotic Agents; Cocaine; Cocaine-Related Disorders; Humans; Outcome Assessment, Health Care; Patient Dropouts; Randomized Controlled Trials as Topic; Risperidone; Severity of Illness Index | 2013 |
Cocaine contamination of banknotes: a review.
Topics: Cocaine; Cocaine-Related Disorders; Equipment Contamination; Humans; Paper | 2017 |
Sub-lethal toxicity and elimination of the cocaine metabolite, benzoylecgonine: a narrative review.
Topics: Cocaine; Humans | 2021 |
39 trial(s) available for cocaine and benzoylecgonine
| Article | Year |
|---|---|
Recurrent coronary vasoconstriction caused by intranasal cocaine: possible role for metabolites.
Topics: Administration, Intranasal; Adult; Aged; Cineangiography; Cocaine; Coronary Angiography; Coronary Vessels; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Recurrence; Vasoconstriction | 1992 |
Validity testing of commercial urine cocaine metabolite assays: I. Assay detection times, individual excretion patterns, and kinetics after cocaine administration to humans.
Topics: Adult; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Male; Radioimmunoassay; Substance-Related Disorders | 1989 |
Validity testing of commercial urine cocaine metabolite assays: II. Sensitivity, specificity, accuracy, and confirmation by gas chromatography/mass spectrometry.
Topics: Adult; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Male; Substance-Related Disorders | 1989 |
Carbamazepine treatment for cocaine dependence.
Topics: Adult; Anticonvulsants; Carbamazepine; Cocaine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Kindling, Neurologic; Male; Middle Aged; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome | 1995 |
Improved performance 4 hours after cocaine.
Topics: Adult; Affect; Attention; Blood Pressure; Cocaine; Cross-Over Studies; Euphoria; Heart Rate; Humans; Male; Psychomotor Performance; Pupil; Reaction Time; Saliva; Skin Temperature; Time Factors | 1993 |
Fluoxetine for cocaine dependence in methadone maintenance: quantitative plasma and urine cocaine/benzoylecgonine concentrations.
Topics: Adult; Cocaine; Female; Fluoxetine; Humans; Male; Methadone; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Substance-Related Disorders | 1993 |
A controlled trial of fluoxetine in crack cocaine dependence.
Topics: Adult; Ambulatory Care; Cocaine; Crack Cocaine; Double-Blind Method; Female; Fluoxetine; Humans; Male; Opioid-Related Disorders; Selective Serotonin Reuptake Inhibitors; Substance Abuse Detection; Treatment Outcome | 1996 |
Effects of cocaine on anterior pituitary and gonadal hormones.
Topics: Administration, Intranasal; Adult; Cocaine; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Pituitary Hormones, Anterior; Prolactin; Testosterone | 1996 |
Passive inhalation of cocaine.
Topics: Administration, Inhalation; Adult; Cocaine; Double-Blind Method; Environmental Exposure; Female; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Narcotics; Occupational Exposure | 1995 |
Pharmacokinetics and pharmacodynamics of cocaine.
Topics: Administration, Inhalation; Administration, Intranasal; Adult; Biological Availability; Cocaine; Cross-Over Studies; Double-Blind Method; Gas Chromatography-Mass Spectrometry; Heart Rate; Humans; Illicit Drugs; Injections, Intravenous; Male; Opioid-Related Disorders; Regression Analysis | 1995 |
Cocaine use immediately prior to entry in an inpatient heroin detoxification unit as a predictor of discharges against medical advice.
Topics: Analgesics, Opioid; Analysis of Variance; Antiemetics; Cocaine; Counseling; Dextropropoxyphene; Diazepam; Female; Heroin Dependence; Humans; Male; Methadone; Patient Discharge; Patient Dropouts; Regression Analysis; Substance Abuse Treatment Centers; Substance-Related Disorders; Time Factors | 1997 |
Measurement properties of quantitative urine benzoylecgonine in clinical trials research.
Topics: Adult; Biomarkers; Cocaine; Double-Blind Method; Female; Humans; Male; Narcotics; Substance Abuse Detection; Substance-Related Disorders | 1997 |
Assessment of cocaine use with quantitative urinalysis and estimation of new uses.
Topics: Adolescent; Adult; Aged; Cocaine; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Narcotics; Opioid-Related Disorders; Single-Blind Method; Substance Abuse Detection | 1997 |
Ritanserin in the treatment of cocaine dependence.
Topics: Adult; Cocaine; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Ritanserin; Serotonin Antagonists; Severity of Illness Index; Substance-Related Disorders | 1997 |
Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans.
Topics: Adult; beta-Thromboglobulin; Bleeding Time; Blood Platelets; Cocaine; Cross-Over Studies; Double-Blind Method; Female; Flow Cytometry; Humans; Male; P-Selectin; Platelet Activation; Platelet Factor 4; Statistics, Nonparametric; Thrombosis; von Willebrand Factor | 2000 |
Risperidone for the treatment of cocaine dependence: randomized, double-blind trial.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Patient Dropouts; Psychotherapy; Recurrence; Risperidone; Time Factors | 2000 |
Amantadine in the treatment of cocaine-dependent patients with severe withdrawal symptoms.
Topics: Amantadine; Ambulatory Care; Cocaine; Cocaine-Related Disorders; Dopamine Agents; Double-Blind Method; Female; Humans; Male; Placebos; Severity of Illness Index; Substance Abuse Detection; Substance Withdrawal Syndrome; Treatment Outcome | 2000 |
Use of hair analysis for confirmation of self-reported cocaine use in users with negative urine tests.
Topics: Adolescent; Adult; Aged; Chromatography, Thin Layer; Cocaine; Cocaine-Related Disorders; Female; Hair; Hair Color; Humans; Male; Middle Aged; Phenotype; Substance Abuse Detection | 2001 |
Dextroamphetamine for cocaine-dependence treatment: a double-blind randomized clinical trial.
Topics: Adult; Behavior Therapy; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Delayed-Action Preparations; Dextroamphetamine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Patient Compliance; Patient Dropouts; Severity of Illness Index; Substance Abuse Detection | 2001 |
Urine toxicology samples in cocaine treatment trials: how many need to be tested?
Topics: Adult; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Fluoxetine; Humans; Male; Predictive Value of Tests; Substance Abuse Detection | 2002 |
Measuring outcome in cocaine clinical trials: a comparison of sweat patches with urine toxicology and participant self-report.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Cocaine; Cocaine-Related Disorders; Female; Humans; Male; Middle Aged; Reagent Kits, Diagnostic; Sensitivity and Specificity; Specimen Handling; Substance Abuse Detection; Sweat; Treatment Outcome | 2003 |
A pilot trial of olanzapine for the treatment of cocaine dependence.
Topics: Adolescent; Adult; Benzodiazepines; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Olanzapine; Pilot Projects; Pirenzepine; Retention, Psychology; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine use.
Topics: Adult; Baclofen; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; GABA Agonists; Humans; Longitudinal Studies; Male; Middle Aged; Substance Abuse Detection; Treatment Outcome | 2003 |
Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence: two double-blind randomized clinical trials.
Topics: Adolescent; Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Double-Blind Method; Female; Heroin Dependence; HIV Infections; Humans; Male; Methadone; Middle Aged; Narcotics; Patient Dropouts; Psychiatric Status Rating Scales; Risperidone; Substance Abuse Detection | 2004 |
A controlled trial of amlodipine for cocaine dependence: a negative report.
Topics: Adult; Ambulatory Care; Amlodipine; Calcium Channel Blockers; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Female; Humans; Male; Middle Aged; Motivation; Patient Compliance; Patient Dropouts; Substance Abuse Detection; Treatment Outcome | 2005 |
Disposition of cocaine and its metabolites in human sweat after controlled cocaine administration.
Topics: Adult; Cocaine; Female; Humans; Male; Substance Abuse Detection; Sweat | 2005 |
A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.
Topics: Administration, Cutaneous; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Evaluation, Preclinical; Female; Humans; Male; Mecamylamine; Methadone; Methadyl Acetate; Narcotics; New York City; Nicotinic Antagonists; Treatment Outcome; Urban Population | 2005 |
A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptoms.
Topics: Adrenergic beta-Antagonists; Adult; Amantadine; Analgesics, Non-Narcotic; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Neurologic Examination; Patient Dropouts; Propranolol; Substance Abuse Detection; Substance Withdrawal Syndrome | 2006 |
Coca tea consumption causes positive urine cocaine assay.
Topics: Adult; Beverages; Bias; Coca; Cocaine; Cocaine-Related Disorders; Drinking Behavior; Drug and Narcotic Control; False Positive Reactions; Feeding Behavior; Female; Fluorescence Polarization Immunoassay; Humans; Immunoassay; Male; Medical History Taking; Reproducibility of Results; South America; Substance Abuse Detection; Time Factors; United States | 2006 |
The SRPHK1 outcome measure for cocaine-dependence trials combines self-report, urine benzoylecgonine levels, and the concordance between the two to determine a cocaine-use status for each study day.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Male; Protein Serine-Threonine Kinases; Severity of Illness Index; Surveys and Questionnaires; Time Factors | 2008 |
Failure of amoxicillin to produce false-positive urine screens for cocaine metabolite.
Topics: Amoxicillin; Anti-Bacterial Agents; Cocaine; False Positive Reactions; Humans; Substance Abuse Detection | 2008 |
A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.
Topics: Administration, Cutaneous; Adult; Affect; Amphetamine; Amphetamines; Analysis of Variance; Cocaine; Dopamine Uptake Inhibitors; Drug Interactions; Female; Homovanillic Acid; Humans; Infusions, Intravenous; Male; Methamphetamine; Methoxyhydroxyphenylglycol; Monitoring, Physiologic; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Prolactin; Selegiline; Statistics, Nonparametric; Substance Withdrawal Syndrome; Young Adult | 2009 |
A double-blind, placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependence.
Topics: Acamprosate; Alcohol Deterrents; Central Nervous System Agents; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Philadelphia; Pilot Projects; Taurine; Treatment Outcome | 2011 |
Aripiprazole and ropinirole treatment for cocaine dependence: evidence from a pilot study.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Cocaine; Cocaine-Related Disorders; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Humans; Indoles; Linear Models; Male; Middle Aged; Pilot Projects; Piperazines; Psychiatric Status Rating Scales; Quinolones; Treatment Outcome; Young Adult | 2011 |
Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Female; GABA Agonists; Humans; Louisiana; Male; Metyrapone; Middle Aged; Oxazepam; Patient Compliance; Patient Dropouts; Pilot Projects; Secondary Prevention; Steroid 11-beta-Hydroxylase; Substance Withdrawal Syndrome | 2012 |
A double-blind, placebo-controlled trial of modafinil for cocaine dependence.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Modafinil; Sex Factors; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult | 2012 |
Cocaine analytes in human hair: evaluation of concentration ratios in different cocaine sources, drug-user populations and surface-contaminated specimens.
Topics: Adolescent; Adult; Biotransformation; Cocaine; Environmental Exposure; Female; Forensic Toxicology; Guidelines as Topic; Hair; Humans; Illicit Drugs; Male; Middle Aged; Psychotropic Drugs; Substance Abuse Detection; Surface Properties; Tissue Distribution; United States; Young Adult | 2012 |
A multisite, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of vigabatrin for treating cocaine dependence.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Double-Blind Method; Female; GABA Agents; Humans; Male; Medication Adherence; Middle Aged; Treatment Outcome; Vigabatrin | 2013 |
A double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence.
Topics: Adolescent; Adult; Alcoholism; Benzhydryl Compounds; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Craving; Double-Blind Method; Female; Humans; Male; Medication Adherence; Middle Aged; Modafinil; Patient Compliance; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult | 2015 |
642 other study(ies) available for cocaine and benzoylecgonine
| Article | Year |
|---|---|
Estimation and disposition of [3H]benzoylecgonine and pharmacological activity of some cocaine metabolites.
Topics: Animals; Brain; Brain Chemistry; Cocaine; In Vitro Techniques; Male; Rats; Time Factors | 1975 |
Simultaneous determination of cocaine and benzoyl ecgonine in urine by gas chromatography with on-column alkylation.
Topics: Alkylation; Chromatography, Gas; Cocaine; Humans | 1977 |
Evaluation of the radioimmunoassay for benzoylecgonine (a cocaine metabolite) in human urine.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Cross Reactions; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Flame Ionization; Humans; Immunoenzyme Techniques; Radioimmunoassay | 1977 |
Incidence of cocaine metabolites in urine specimens from medical examiners' cases.
Topics: Cadaver; Cocaine; Humans; Morphine; Radioimmunoassay | 1979 |
Quantitative determination of benzoylecgonine and cocaine in human biofluids by gas-liquid chromatography.
Topics: Chromatography, Gas; Chromatography, Liquid; Cocaine; Humans | 1977 |
Detection of benzoylecgonine in human urine.
Topics: Chromatography, Thin Layer; Cocaine; Humans; Mass Screening; Microchemistry; Substance-Related Disorders | 1977 |
Thin-layer chromatographic analysis of cocaine and benzoylecgonine in urine.
Topics: Chromatography, Thin Layer; Cocaine; Evaluation Studies as Topic; Indicators and Reagents; Mass Screening; Microchemistry | 1975 |
Gas-liquid chromatographic determination of cocaine and benzoylecgonine in urine.
Topics: Chromatography, Gas; Cocaine; Humans | 1976 |
Characterization of the sodium channel blocking properties of the major metabolites of cocaine in single cardiac myocytes.
Topics: Animals; Cocaine; Electrophysiology; Guinea Pigs; Heart; Myocardium; Sodium Channels | 1992 |
Cocaine-induced ACTH secretion: dependence of plasma levels of the drug and mode of exposure.
Topics: Adrenocorticotropic Hormone; Animals; Cocaine; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Implants; Male; Radioimmunoassay; Rats; Rats, Inbred Strains | 1992 |
Effects of benzoylecgonine on the behavior of suckling rats: a preliminary report.
Topics: Animals; Animals, Suckling; Anticonvulsants; Antipsychotic Agents; Behavior, Animal; Brain; Cocaine; Female; Humans; Male; Rats; Rats, Inbred Strains; Seizures | 1992 |
Passive exposure to cocaine in medical personnel and its effect on urine drug screening tests.
Topics: Administration, Cutaneous; Aerosols; Cocaine; Humans; Medical Staff; Occupational Exposure; Substance Abuse Detection | 1992 |
Cocaine liberation from body packets in an in vitro model.
Topics: Aluminum Hydroxide; Antacids; Cellophane; Chromatography, High Pressure Liquid; Cocaine; Condoms; Digestive System; Drug Combinations; Electrolytes; Foreign Bodies; Gastric Juice; Humans; In Vitro Techniques; Magnesium Hydroxide; Paper; Polyethylene Glycols | 1992 |
The presence of cocaine and benzoylecgonine in rat cerebrospinal fluid after the intravenous administration of cocaine.
Topics: Animals; Cocaine; Half-Life; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1992 |
The accumulation and disappearance of cocaine and benzoylecgonine in rat hair following prolonged administration of cocaine.
Topics: Animals; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Half-Life; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley | 1992 |
Effects of ethanol on cocaine metabolism: formation of cocaethylene and norcocaethylene.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cocaine; Ethanol; Injections, Intraperitoneal; Liver; Male; Rats; Rats, Wistar; Time Factors | 1992 |
Hair analysis for drugs of abuse. V. The facility in incorporation of cocaine into hair over its major metabolites, benzoylecgonine and ecgonine methyl ester.
Topics: Animals; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Illicit Drugs; Male; Rats; Substance Abuse Detection | 1992 |
Determination of cocaine and benzoylecgonine in human amniotic fluid using high flow solid-phase extraction columns and HPLC.
Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Cocaine; Female; Gestational Age; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Substance Abuse Detection; Substance-Related Disorders | 1992 |
Cocaine impairs gonadotropin secretion in oophorectomized monkeys.
Topics: Analysis of Variance; Animals; Cocaine; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Luteinizing Hormone; Macaca fascicularis; Ovariectomy | 1992 |
Preparation of a fluorescent derivative of benzoylecgonine, and preliminary studies of its application to the analysis of urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Fluorescent Dyes; Humans; Quinoxalines; Reproducibility of Results; Spectrometry, Fluorescence | 1992 |
The effects of inhibition of plasma cholinesterase and hepatic microsomal enzyme activity on cocaine, benzoylecgonine, ecgonine methyl ester, and norcocaine blood levels in pigs.
Topics: Animals; Biotransformation; Cholinesterases; Cocaine; Half-Life; Male; Metabolic Clearance Rate; Microsomes, Liver; Swine; Tetraisopropylpyrophosphamide | 1992 |
A rapid gas chromatographic method for the fingerprinting of illicit cocaine samples.
Topics: Bridged Bicyclo Compounds; Chromatography, Gas; Cocaine; Cyclobutanes; Illicit Drugs; Time Factors | 1992 |
Direct analysis for cocaine in urine by high-performance liquid chromatography (HPLC) using a column-switching technique.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 1992 |
Insect larvae used to detect cocaine poisoning in a decomposed body.
Topics: Adult; Animals; Chromatography, Gas; Cocaine; Diptera; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Larva; Male; Muscles; Poisoning; Postmortem Changes; Radioimmunoassay | 1992 |
Occupational exposure to cocaine involving crime lab personnel.
Topics: Air Pollution, Indoor; Cocaine; Dust; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Medical Laboratory Personnel; Occupational Exposure; Protective Devices | 1992 |
Determination of the enantiomeric composition of samples of cocaine by normal-phase high-performance liquid chromatography with UV detection.
Topics: Chromatography, High Pressure Liquid; Cocaine; Spectrophotometry, Ultraviolet; Stereoisomerism | 1992 |
Accumulation of cocaine in maternal and fetal hair; the dose response curve.
Topics: Animals; Biomarkers; Cocaine; Dose-Response Relationship, Drug; Female; Fetus; Guinea Pigs; Hair; Humans; Injections, Subcutaneous; Maternal-Fetal Exchange; Pregnancy; Substance Abuse Detection; Substance-Related Disorders | 1992 |
Cocaine inhibits mating-induced, but not human chorionic gonadotropin-stimulated, ovulation in the rabbit.
Topics: Animals; Chorionic Gonadotropin; Cocaine; Corpus Luteum; Female; Follicle Stimulating Hormone; Hypothalamus; Injections, Subcutaneous; Luteal Phase; Luteinizing Hormone; Ovary; Ovulation; Pituitary Gland; Progesterone; Pseudopregnancy; Rabbits; Sexual Behavior, Animal | 1992 |
Effect of intranasal cocaine on the urine drug screen for benzoylecgonine.
Topics: Administration, Intranasal; Anesthetics, Local; Cocaine; Humans; Nose; Random Allocation; Substance Abuse Detection | 1992 |
In vitro exposure of preimplantation mouse embryos to cocaine and benzoylecgonine inhibits subsequent development.
Topics: Animals; Cocaine; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Development; Female; Mice; Pregnancy; Superovulation | 1992 |
Occult cocaine exposure in children.
Topics: Adult; Child of Impaired Parents; Child, Preschool; Cocaine; Dronabinol; Emergency Service, Hospital; Environmental Exposure; Female; Humans; Infant; Infant, Newborn; Male; Marijuana Abuse; Mass Screening; Population Surveillance; Prevalence; Sampling Studies; Substance Abuse Detection; Substance-Related Disorders; Urban Population | 1991 |
Cocaine and metabolite concentrations in the fetal guinea pig after chronic maternal cocaine administration.
Topics: Amniotic Fluid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Lidocaine; Maternal-Fetal Exchange; Pregnancy | 1992 |
Passive inhalation of cocaine.
Topics: Administration, Inhalation; Adult; Cocaine; Environmental Exposure; Humans; Male | 1991 |
A rapid method for the determination of cocaine in brain tissue.
Topics: Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Humans; Lipase | 1991 |
Effects of prenatal cocaine exposure on perinatal morbidity and postnatal growth in the rabbit.
Topics: Abortion, Spontaneous; Animals; Animals, Newborn; Cocaine; Disease Models, Animal; Female; Fetal Death; Fetal Growth Retardation; Fetus; Humans; Infant, Newborn; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rabbits | 1991 |
Determination of cocaine, benzoylecgonine and ecgonine methyl ester in plasma by reversed-phase high-performance liquid chromatography.
Topics: Animals; Cocaine; Electrochemistry; Female; Hydrogen-Ion Concentration; Sheep; Spectrophotometry, Ultraviolet | 1991 |
Site-dependent postmortem changes in blood cocaine concentrations.
Topics: Adolescent; Adult; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Postmortem Changes; Suicide; Wounds, Gunshot | 1991 |
Cocaine pharmacokinetics in the pregnant guinea pig.
Topics: Animals; Cocaine; Female; Guinea Pigs; Metabolic Clearance Rate; Pregnancy; Pregnancy, Animal | 1991 |
Fluoxetine for cocaine abuse in methadone patients: preliminary findings.
Topics: Adult; Cocaine; Female; Fluoxetine; Heroin Dependence; Humans; Male; Methadone; Substance-Related Disorders | 1990 |
Incidence of intrauterine cocaine exposure in a suburban setting.
Topics: Cocaine; Female; Fetus; Humans; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Socioeconomic Factors; Substance-Related Disorders; Suburban Population; Surveys and Questionnaires | 1991 |
Human liver cocaine esterases: ethanol-mediated formation of ethylcocaine.
Topics: Carboxylic Ester Hydrolases; Chromatography, Gel; Cocaine; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Liver; Molecular Structure; Molecular Weight | 1991 |
Findings in newborns of cocaine-abusing mothers.
Topics: Autopsy; Brain Chemistry; Cause of Death; Cocaine; Female; Fetal Death; Humans; Infant, Newborn; Liver; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Substance-Related Disorders | 1991 |
Benzoylecgonine (cocaine metabolite) detection in hair samples of jail detainees using radioimmunoassay (RIA) and gas chromatography/mass spectrometry (GC/MS).
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Prisoners; Radioimmunoassay | 1991 |
Cocaine hydrochloride and benzoylecgonine have no in vitro inhibitory effect against Neisseria gonorrhoeae.
Topics: Anti-Bacterial Agents; Cocaine; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae | 1991 |
Cocaine metabolite detection in homicide victims.
Topics: Black or African American; Cocaine; Female; Georgia; Homicide; Humans; Male; Population Surveillance; Retrospective Studies; Wounds, Gunshot | 1991 |
Cocaine metabolites in pre-Columbian mummy hair.
Topics: Chile; Cocaine; Hair; History, Ancient; History, Medieval; Humans; Mummies; Peru | 1991 |
Performance of techniques used to detect drugs of abuse in urine: study based on external quality assessment.
Topics: Amphetamine; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; False Positive Reactions; Humans; Immunoassay; Methadone; Morphine; Quality Control | 1991 |
Cocaine inhalation in the rat: pharmacokinetics and cardiovascular response.
Topics: Absorption; Administration, Inhalation; Animals; Blood Pressure; Cocaine; Heart Rate; Injections, Intravenous; Lung; Male; Rats; Rats, Inbred Strains; Tissue Distribution; Volatilization | 1991 |
Urine drug screening for cocaine after lacrimal surgery.
Topics: Adult; Aged; Aged, 80 and over; Child, Preschool; Chromatography, Gas; Cocaine; Dacryocystorhinostomy; Female; Humans; Male; Middle Aged; Postoperative Period; Time Factors | 1991 |
Simultaneous determination of cocaine and its metabolites with caffeine in rat serum microsamples by high-performance liquid chromatography.
Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cocaine; Drug Stability; Male; Microchemistry; Rats | 1990 |
Simultaneous detection in urine of cocaine and its main metabolites.
Topics: Chemical Phenomena; Chemistry, Physical; Chromatography, Gas; Cocaine; Fluorescence Polarization Immunoassay; Humans; Indicators and Reagents; Solutions; Trimethylsilyl Compounds | 1990 |
Cocaine disrupts estrous cyclicity and alters the reproductive neuroendocrine axis in the rat.
Topics: Animals; Behavior, Animal; Body Weight; Cocaine; Dopamine; Estrus; Female; Follicle Stimulating Hormone; Hypothalamus; Luteinizing Hormone; Neurosecretory Systems; Norepinephrine; Ovulation; Pituitary Hormone-Releasing Hormones; Prolactin; Rats; Serotonin | 1990 |
Fetal and maternal cocaine levels peak rapidly following intragastric administration in the rat.
Topics: Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Female; Maternal-Fetal Exchange; Metabolic Clearance Rate; Pregnancy; Rats; Rats, Inbred Strains | 1990 |
Prolonged presence of metabolite in urine after compulsive cocaine use.
Topics: Adult; Chromatography, Thin Layer; Cocaine; Hospitalization; Humans; Immunoenzyme Techniques; Male; Psychiatric Status Rating Scales; Substance-Related Disorders; Time Factors | 1990 |
TAC topical anesthesia produces positive urine tests for cocaine.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Child; Child, Preschool; Cocaine; Drug Combinations; Epinephrine; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Tetracaine | 1990 |
Effect of cocaine and cocaine metabolites on cerebral arteries in vitro.
Topics: Animals; Cats; Cerebral Arteries; Cocaine; Female; In Vitro Techniques; Male; Norepinephrine; Serotonin; Vasoconstrictor Agents | 1990 |
Sudden death from acute cocaine intoxication in Virginia in 1988.
Topics: Cardiomyopathies; Cocaine; Coronary Disease; Death, Sudden; Ethanol; Female; Heart; Humans; Male; Organ Size; Poisoning; Sex Factors; Substance-Related Disorders; Virginia | 1990 |
High-performance liquid chromatography with column switching for the determination of cocaine and benzoylecgonine concentrations in vitreous humor.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Vitreous Body | 1990 |
The determination of drugs of abuse in whole blood by means of FPIA and EMIT-dau immunoassays--a comparative study.
Topics: Amphetamines; Barbiturates; Benzodiazepines; Cannabinoids; Cocaine; Fluorescence Polarization Immunoassay; Humans; Illicit Drugs; Immunoenzyme Techniques; Narcotics; Predictive Value of Tests | 1990 |
TAC use and absorption of cocaine in a pediatric emergency department.
Topics: Administration, Topical; Adolescent; Anesthetics, Local; Child; Child, Preschool; Chromatography, Gas; Cocaine; Drug Combinations; Emergencies; Emergency Service, Hospital; Epinephrine; Humans; Infant; Pediatrics; Skin Absorption; Tetracaine | 1990 |
Variations in abundance of the molecular ion of the derivatized cocaine metabolite benzoylecgonine.
Topics: Analysis of Variance; Cocaine; False Positive Reactions; Humans; Mass Spectrometry; Substance Abuse Detection | 1990 |
Microassay for the simultaneous determination of cocaine, norcocaine, benzoylecgonine and benzoylnorecgonine by high-performance liquid chromatography.
Topics: Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Maternal-Fetal Exchange; Pregnancy | 1990 |
Cocaine and traffic accident fatalities in New York City.
Topics: Accidents, Traffic; Adolescent; Adult; Cocaine; Humans; Male; Middle Aged; New York City | 1990 |
A cocaine body packer with normal abdominal plain radiograms. Value of drug detection in urine and contrast study of the bowel.
Topics: Adult; Cocaine; Contrast Media; Crime; Female; Foreign Bodies; Humans; Intestines; Male; Predictive Value of Tests; Radiography | 1990 |
Vascular lesions in intestinal ischemia induced by cocaine-alcohol abuse: report of a fatal case due to overdose.
Topics: Adult; Alcoholic Intoxication; Arterioles; Cocaine; Drug Overdose; Ethanol; Humans; Intestine, Small; Ischemia; Male; Substance-Related Disorders | 1990 |
Prolonged detection period for cocaine and metabolite.
Topics: Cocaine; Humans; Saliva; Substance-Related Disorders | 1990 |
Detection of benzoylecgonine (cocaine metabolite) in urine: a cost-effective low risk immunoassay procedure.
Topics: Cocaine; Humans; Immunoassay; Substance-Related Disorders | 1990 |
Mechanism of false-negative urine cannabinoid immunoassay screens by Visine eyedrops.
Topics: Amphetamine; Benzalkonium Compounds; Cannabinoids; Cocaine; Dronabinol; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Immunoassay; Morphine; Nasal Decongestants; Oxazepam; Phencyclidine; Secobarbital; Ultrafiltration | 1989 |
Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following chronic subcutaneous administration of cocaine during gestation in rats.
Topics: Animals; Brain; Cocaine; Female; Fetus; Injections, Subcutaneous; Pregnancy; Rats; Rats, Inbred Strains | 1989 |
Direct analysis of drugs by continuous-flow fast-atom bombardment and tandem mass spectrometry.
Topics: Cocaine; Mass Spectrometry; Penicillin G; Phentolamine; Spectrometry, Mass, Fast Atom Bombardment | 1989 |
Studies on the stability and detection of cocaine, benzoylecgonine, and 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in whole blood using Abuscreen radioimmunoassay.
Topics: Blood Preservation; Chromatography, Gas; Cocaine; Dronabinol; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Radioimmunoassay; Refrigeration; Substance-Related Disorders | 1989 |
Determination of gestational cocaine exposure by hair analysis.
Topics: Adult; Cocaine; Female; Hair; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Complications; Radioimmunoassay; Substance-Related Disorders | 1989 |
Determination of cocaine and selected metabolites in canine and human serum by reversed-phase high-performance liquid chromatography on coupled cyanopropyl and silica columns.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Dogs; Humans; Spectrophotometry, Ultraviolet | 1989 |
Paternal behavioral mutagenesis.
Topics: Animals; Birth Weight; Body Weight; Cocaine; Estradiol; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Resorption; Male; Mutagens; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Factors; Testosterone | 1989 |
Rapid confirmation of enzyme multiplied immunoassay technique (EMIT) cocaine positive urine samples by capillary gas-liquid chromatography/nitrogen phosphorus detection (GLC/NPD).
Topics: Chromatography, Gas; Cocaine; Humans; Immunoenzyme Techniques; Substance-Related Disorders | 1989 |
Evaluation of the Keystone Diagnostic Quik Test. A paper chromatography test for drugs of abuse in urine.
Topics: Chromatography, Paper; Cocaine; Evaluation Studies as Topic; Humans; Phencyclidine; Reagent Kits, Diagnostic; Sensitivity and Specificity; Substance-Related Disorders | 1989 |
Thin-layer chromatography of benzoylecgonine: a rapid qualitative method for confirming the EMIT Urine Cocaine Metabolite Assays.
Topics: Chromatography, Thin Layer; Cocaine; Humans; Immunoenzyme Techniques | 1989 |
Urine testing during treatment of cocaine dependence.
Topics: Cocaine; Female; Humans; Immunoenzyme Techniques; Metabolic Clearance Rate; Social Environment; Substance Abuse Detection; Substance-Related Disorders | 1989 |
Effect of cocaine in tissues on the development rate of Boettcherisca peregrina (Diptera: Sarcophagidae).
Topics: Animals; Cocaine; Diptera; Larva; Liver; Rabbits | 1989 |
Ophthalmic use of cocaine and the urine test for benzoylecgonine.
Topics: Adult; Cocaine; Female; Humans; Male; Middle Aged; Ophthalmic Solutions; Substance-Related Disorders | 1989 |
Cocaine effects on the developing central nervous system: behavioral, psychopharmacological, and neurochemical studies.
Topics: Animals; Behavior, Animal; Brain; Cocaine; Dopamine; Dose-Response Relationship, Drug; Female; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Reflex | 1989 |
Cocaine and pregnancy: clinical and toxicological implications for the neonate.
Topics: Abnormalities, Drug-Induced; Adult; Cocaine; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Small for Gestational Age; Pregnancy; Prenatal Exposure Delayed Effects; Substance-Related Disorders; Urogenital Abnormalities | 1989 |
Validity testing of commercial urine cocaine metabolite assays: III. Evaluation of an enzyme-linked immunosorbent assay (ELISA) for detection of cocaine and cocaine metabolite.
Topics: Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Male; Predictive Value of Tests | 1989 |
Cocaine exposure among children seen at a pediatric hospital.
Topics: Adolescent; Adult; Breast Feeding; Child; Child, Preschool; Cocaine; Cross-Sectional Studies; Female; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Male; Massachusetts; Neonatal Abstinence Syndrome; Substance-Related Disorders | 1989 |
Extending the detection limit of the TDx fluorescence polarization immunoassay for benzoylecgonine in urine.
Topics: Autoanalysis; Cocaine; False Negative Reactions; Fluorescence Polarization; Humans; Immunoassay; Mathematics; Solanine; Statistics as Topic; Substance-Related Disorders | 1989 |
Confirmation of drugs of abuse in urine drug screens by direct exposure probe mass spectrometry.
Topics: Cocaine; Dronabinol; Humans; Illicit Drugs; Mass Spectrometry; Phencyclidine | 1988 |
Detection of drugs in the urine of body-packers.
Topics: Cocaine; Crime; Evaluation Studies as Topic; Foreign Bodies; Foreign-Body Migration; Heroin; Humans; Immunoenzyme Techniques; Morphine; Radiography; Rectum | 1988 |
Cocaine increases natural killer cell activity.
Topics: Adult; Cocaine; Cytotoxicity, Immunologic; Epinephrine; Female; Humans; Killer Cells, Natural; Lymphocytes; Male; Receptors, Fc; Receptors, IgG; Time Factors | 1986 |
[Determination of benzoyl ecgonine in human scalp hair following cocaine abuse by gas chromatography-mass spectrometry (GC-MS)].
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance-Related Disorders | 1988 |
Protracted elimination of cocaine metabolites in long-term high-dose cocaine abusers.
Topics: Adult; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Male; Substance-Related Disorders; Time Factors | 1988 |
A rapid method for the extraction of cocaine and benzoylecgonine from body fluids.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Methods | 1988 |
Release of vesicular noradrenaline in the rat tail artery induced by cocaine.
Topics: Animals; Arteries; Calcium; Cocaine; Desipramine; Dose-Response Relationship, Drug; Male; Methoxyhydroxyphenylglycol; Microscopy, Electron; Monoamine Oxidase; Norepinephrine; Rats; Rats, Inbred Strains; Tail | 1988 |
The effect of cocaine abuse on birth weight and gestational age.
Topics: Adolescent; Adult; Birth Weight; Cocaine; Female; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; New York City; Pregnancy; Regression Analysis; Retrospective Studies; Socioeconomic Factors; Substance-Related Disorders; Urban Population | 1988 |
Validity testing of the TDx Cocaine Metabolite Assay with human specimens obtained after intravenous cocaine administration.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Male; Substance-Related Disorders; Time Factors | 1988 |
Single-reagent polarisation fluoroimmunoassay for the cocaine metabolite, benzoylecgonine, in urine.
Topics: Antibody Specificity; Cocaine; Cross Reactions; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Kinetics | 1986 |
Cocaine detection during toxicology screening of a university medical center patient population.
Topics: Adult; California; Child, Preschool; Cocaine; Female; Hospitals, University; Humans; Infant; Infant, Newborn; Inpatients; Male; Middle Aged; Patients; Retrospective Studies | 1987 |
Determination of benzoylecgonine and cocaine in biologic fluids by automated gas chromatography.
Topics: Autoanalysis; Chromatography, Gas; Cocaine; Humans; Indicators and Reagents | 1987 |
Radioimmunological determination of cocaine in human hair.
Topics: Cocaine; Hair; Humans; Radioimmunoassay; Substance-Related Disorders | 1987 |
Detection of cocaine metabolite in perspiration stain, menstrual bloodstain, and hair.
Topics: Blood Stains; Cocaine; Female; Hair; Humans; Male; Menstruation; Radioimmunoassay; Sweat | 1986 |
Cocaine-related deaths in Pima County, Arizona, 1982-1984.
Topics: Adult; Arizona; Chromatography, Thin Layer; Cocaine; Female; Gastrointestinal Contents; Humans; Male; Middle Aged; Pulmonary Edema; Radioimmunoassay; Substance-Related Disorders | 1986 |
Detection of cocaine in rats from analysis of hair.
Topics: Animals; Cocaine; Hair; Radioimmunoassay; Rats | 1987 |
Acute myocardial infarction following cocaine abuse in a young woman with normal coronary arteries.
Topics: Adult; Cocaine; Coronary Vessels; Female; Humans; Myocardial Infarction; Substance-Related Disorders | 1985 |
Brain concentrations of cocaine and benzoylecgonine in fatal cases.
Topics: Biotransformation; Blood-Brain Barrier; Brain; Cocaine; Humans; Liver; Radioimmunoassay | 1985 |
Radioimmunoassay of benzoylecgonine in samples of forensic interest.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cocaine; Cross Reactions; Humans; Mass Spectrometry; Radioimmunoassay; Reagent Kits, Diagnostic | 1984 |
Cocaine radioimmunoassay--structure versus reactivity.
Topics: Cocaine; Epitopes; Radioimmunoassay; Structure-Activity Relationship | 1981 |
In vivo and in vitro studies on cocaine metabolism: ecgonine methyl ester as a major metabolite of cocaine.
Topics: Animals; Biotransformation; Cocaine; Dogs; Esterases; Forensic Medicine; Liver; Male; Metabolic Clearance Rate; Rabbits | 1984 |
Quantitation of cocaine, benzoylecgonine and ecgonine methyl ester by GC-CI-SIM after Extrelut extraction.
Topics: Animals; Biotransformation; Cocaine; Diatomaceous Earth; Dogs; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Resins, Plant | 1984 |
Rapid quantitation of cocaine and benzoylecgonine in urine by "on column" capillary gaschromatography after "Extrelut" extraction.
Topics: Chromatography, Gas; Cocaine; Humans | 1984 |
The determination of cocaine and its major metabolite, benzoylecgonine, in postmortem fluids and tissues by computerized gas chromatography/mass spectrometry.
Topics: Autopsy; Cocaine; Gas Chromatography-Mass Spectrometry; Humans | 1983 |
Prediction of stability in pharmaceutical preparations XX: stability evaluation and bioanalysis of cocaine and benzoylecgonine by high-performance liquid chromatography.
Topics: Buffers; Catalysis; Chromatography, High Pressure Liquid; Cocaine; Drug Stability; Erythrocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Potentiometry | 1983 |
Study of the stability of cocaine and benzoylecgonine, its major metabolite, in blood samples.
Topics: California; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Toxicology | 1982 |
Potential errors in benzoylecgonine and cocaine analysis.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Hydrogen-Ion Concentration | 1981 |
TLC analysis of urine for benzoylecgonine and norpropoxyphene.
Topics: Chromatography, Thin Layer; Cocaine; Dextropropoxyphene; Humans; Methods | 1980 |
Qualitative screening procedure for the detection of benzoyl ecgonine in the urine of greyhounds.
Topics: Animals; Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Dogs; Doping in Sports; Time Factors | 1980 |
Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein.
Topics: Animals; Blotting, Western; Carboxylic Ester Hydrolases; Cocaine; Male; Rats; Rats, Wistar; Tissue Distribution | 1995 |
Comparison of cocaine and opiate exposures between young urban and suburban children.
Topics: Child, Preschool; Cocaine; Humans; Illicit Drugs; Infant; Narcotics; Prevalence; Substance-Related Disorders; Suburban Health; United States; Urban Health | 1995 |
The effect of cocaine and its metabolites on Sertoli cell function.
Topics: Androgen-Binding Protein; Animals; Cells, Cultured; Cocaine; In Vitro Techniques; Male; Narcotics; Rats; Rats, Sprague-Dawley; Sertoli Cells; Time Factors; Transferrin | 1996 |
Comparison of the effects of cocaine and its metabolites on cardiovascular function in anesthetized rats.
Topics: Animals; Cocaine; Electrocardiography; Electrophysiology; Hemodynamics; Infusions, Intravenous; Male; Rats; Structure-Activity Relationship | 1993 |
Validation of a rapid urine screening assay for cocaine use among pregnant emergency patients.
Topics: Adult; Chromatography, Thin Layer; Cocaine; Evaluation Studies as Topic; Female; Gas Chromatography-Mass Spectrometry; Humans; Latex Fixation Tests; Pregnancy; Reproducibility of Results; Substance Abuse Detection | 1995 |
OnLine kinetic microparticle immunoassay of cannabinoids, morphine, and benzoylecgonine in serum.
Topics: Cannabinoids; Cocaine; Immunoassay; Indicators and Reagents; Kinetics; Microspheres; Morphine; Substance Abuse Detection | 1995 |
Increased blood and brain cocaine concentrations with ethanol cotreatment in mice.
Topics: Analysis of Variance; Animals; Brain; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Male; Mice; Mice, Inbred ICR | 1995 |
Pharmacokinetics and metabolism of cocaine in maternal and fetal guinea pigs.
Topics: Animals; Animals, Newborn; Biotransformation; Cocaine; Female; Fetus; Guinea Pigs; Injections, Intravenous; Kinetics; Maternal-Fetal Exchange; Microsomes; Placenta; Pregnancy; Sodium Fluoride; Time Factors; Tissue Distribution | 1995 |
Confirmation and quantitation of cocaine, benzoylecgonine, ecgonine methyl ester, and cocaethylene by gas chromatography/mass spectrometry. Use of microwave irradiation for rapid preparation of trimethylsilyl and T-butyldimethylsilyl derivatives.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Microwaves; Trimethylsilyl Compounds | 1995 |
Occult cocaine and opiate exposure in children and associated physical findings.
Topics: Blood Pressure; Body Constitution; Body Weight; Child; Child, Preschool; Cocaine; Emergency Service, Hospital; Environmental Exposure; Female; Head; Humans; Infant; Infant, Newborn; Male; Michigan; Narcotics; Pediatrics; Prospective Studies; Urban Population | 1995 |
A fiber-optic cocaine biosensor.
Topics: Antibodies, Monoclonal; Binding, Competitive; Biosensing Techniques; Calibration; Cocaine; Fluorescein; Fluoresceins; Immunoconjugates; Kinetics; Sensitivity and Specificity; Spectrometry, Fluorescence; Time Factors | 1995 |
Relation between meconium concentration of the cocaine metabolite benzoylecgonine and fetal growth.
Topics: Birth Weight; Cocaine; Embryonic and Fetal Development; Female; Humans; Infant, Newborn; Linear Models; Meconium; Pregnancy; Prenatal Exposure Delayed Effects | 1995 |
Clinical interpretation of urine cocaine and metabolites in emergency department patients.
Topics: Cocaine; Emergency Service, Hospital; Humans; Office Visits; Substance Abuse Detection; Substance-Related Disorders | 1995 |
Fatal injuries after cocaine use as a leading cause of death among young adults in New York City.
Topics: Adolescent; Adult; Cause of Death; Cocaine; Ethanol; Female; Humans; Male; New York City; Substance-Related Disorders; Wounds and Injuries | 1995 |
Response of the human hepatic tissue cultures Hep-G2 and WRL-68 to cocaine.
Topics: Carcinoma, Hepatocellular; Cell Death; Cell Division; Cell Line; Chromatography, Gas; Cocaine; Humans; Liver; Mass Spectrometry; Tumor Cells, Cultured | 1995 |
Role of metabolism in cocaine-induced immunosuppression in splenocyte cultures from B6C3F1 female mice.
Topics: Animals; Antibody Formation; Cells, Cultured; Cocaine; Cytochrome P-450 Enzyme System; Erythrocytes; Female; Hepatitis, Animal; Immune Tolerance; Immunosuppression Therapy; Liver; Mice; Microsomes, Liver; Random Allocation; Sheep; Spleen | 1995 |
Stimulatory effects of cocaine and its metabolites on IM-9 human B-lymphoblastoid cells.
Topics: B-Lymphocytes; Cell Line; Chromatography, High Pressure Liquid; Cocaine; Drug Stability; Humans; Lymphocyte Activation; Tetradecanoylphorbol Acetate | 1995 |
Cocaine, opiates, and ethanol in homicides in New York City: 1990 and 1991.
Topics: Adolescent; Adult; Cocaine; Ethanol; Ethnicity; Female; Homicide; Humans; Male; Middle Aged; Narcotics; New York City; Time Factors | 1995 |
Detection of drugs-of-abuse in meconium of a stillborn baby and in stool of a deceased 41-day-old infant.
Topics: Adult; Cocaine; Feces; Female; Fetal Death; Humans; Hydrocephalus; Infant; Infant, Newborn; Male; Meconium; Morphine; Pregnancy; Substance-Related Disorders | 1995 |
Head growth in cocaine-exposed infants: relationship to neonate hair level.
Topics: Adult; Cocaine; Cross-Sectional Studies; Female; Hair; Head; Humans; Infant, Newborn; Male; Maternal Behavior; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Substance-Related Disorders | 1995 |
Simultaneous determination of opiates, cocaine and major metabolites of cocaine in human hair by gas chromotography/mass spectrometry (GC/MS).
Topics: Adolescent; Adult; Calibration; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Ethylmorphine; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Male; Morphine; Morphine Derivatives; Narcotics; Reproducibility of Results | 1995 |
Detection of cocaine, norcocaine, and cocaethylene in the meconium of premature neonates.
Topics: Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Infant, Premature; Male; Meconium; Pregnancy; Pregnancy Complications; Prospective Studies; Substance Abuse Detection; Urine | 1994 |
Hair and urine analysis: relative distribution of drugs and their metabolites.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Morphine; Morphine Derivatives; Narcotics; Substance-Related Disorders | 1995 |
Testing human hair for drugs of abuse. IV. Environmental cocaine contamination and washing effects.
Topics: Air Pollution; Cocaine; Decontamination; Environmental Exposure; Hair; Humans | 1995 |
Responsiveness to cocaine challenge in adult rats following prenatal exposure to cocaine.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Cocaine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Eating; Female; Injections, Subcutaneous; Male; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sex Characteristics; Weight Gain | 1994 |
Cocaine and benzoylecgonine constrict cerebral arteries by different mechanisms.
Topics: Animals; Calcium; Cats; Cerebral Arteries; Cocaine; Female; Male; Norepinephrine; Oxidopamine; Prazosin; Ryanodine; Sympathectomy, Chemical; Vasoconstriction; Vasomotor System; Verapamil; Yohimbine | 1995 |
Monoamine uptake inhibitors alter cocaine pharmacokinetics.
Topics: Animals; Biotransformation; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Interactions; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley | 1993 |
Benzoylecgonine and ecgonine methyl ester concentrations in urine specimens.
Topics: Chromatography, Gas; Cocaine; Humans; Immunoassay; Substance Abuse Detection | 1995 |
Sensitivity and specificity of cocaine metabolite screening in view of the analytical performance of a fluorescence polarisation immunoassay.
Topics: Cocaine; Fluorescence Polarization Immunoassay; Humans; Sensitivity and Specificity; Substance Abuse Detection | 1994 |
Prevalence of fetal exposure to cocaine in Toronto, 1990-1991.
Topics: Adolescent; Adult; Canada; Cocaine; Female; Fetus; Hair; Humans; Infant, Newborn; Middle Aged; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Substance-Related Disorders | 1994 |
Effects of labetalol on cocaine pharmacokinetics in neonatal piglets.
Topics: Animals; Animals, Newborn; Cocaine; Drug Evaluation, Preclinical; Labetalol; Models, Biological; Swine | 1993 |
Maternal cocaine use without evidence of fetal exposure.
Topics: Adult; Cocaine; Cotinine; Female; Hair; Humans; Infant, Newborn; Meconium; Mothers; Narcotics; Nicotine; Placenta; Pregnancy; Smoking; Substance Abuse, Intravenous | 1994 |
High-performance liquid chromatographic confirmation of cocaine and benzoylecgonine in biological samples using photodiode-array detection after toxicological screening.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cocaine; Humans; Hydrogen-Ion Concentration; Narcotics; Solvents; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substance-Related Disorders | 1994 |
Sensitive assay for cocaine and benzoylecgonine using solid-phase extraction and gas chromatography.
Topics: Chromatography, Gas; Cocaine; Humans; Hydrogen-Ion Concentration; Microchemistry; Sensitivity and Specificity | 1994 |
Simultaneous detection of cocaine and heroin metabolites in urine by solid-phase extraction and gas chromatography-mass spectrometry.
Topics: Cocaine; Deuterium; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Hydrogen-Ion Concentration; Microchemistry; Morphine Derivatives; Reproducibility of Results; Sensitivity and Specificity | 1994 |
The analysis of cocaine and its metabolites by liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry (LC/APCI-MS).
Topics: Chromatography, High Pressure Liquid; Cocaine; Evaluation Studies as Topic; Forensic Medicine; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion; Substance Abuse Detection | 1994 |
The effect of hepatectomy and plasma cholinesterase inhibition on cocaine metabolism and cardiovascular responses in pigs.
Topics: Animals; Cardiovascular System; Cholinesterase Inhibitors; Cholinesterases; Cocaine; Hemodynamics; Hepatectomy; Liver; Male; Osmolar Concentration; Swine; Tetraisopropylpyrophosphamide | 1994 |
Causes of differential cardiovascular sensitivity to cocaine. II: Sympathetic, metabolic and cardiac effects.
Topics: Anesthesia; Animals; Blood Pressure; Brain; Cardiac Output; Cocaine; Heart Rate; Hemodynamics; Male; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1994 |
Cocaethylene in meconium specimens.
Topics: Cocaine; Cross Reactions; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Meconium | 1994 |
Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine.
Topics: Amino Acid Sequence; Carboxylic Ester Hydrolases; Cocaine; Ethanol; Humans; Liver; Molecular Sequence Data; Peptide Fragments; Trypsin | 1994 |
Determination of cocaine usage in pregnant women by a urinary EMIT drug screen and GC-MS analyses.
Topics: Cocaine; Enzyme Multiplied Immunoassay Technique; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Pregnancy Complications; Substance Abuse Detection | 1994 |
Maternal and fetal brain and plasma levels of cocaine and benzoylecgonine after acute or chronic maternal intravenous administration of cocaine.
Topics: Animals; Brain; Cocaine; Female; Fetus; Injections, Intravenous; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1994 |
Effects of cocaine, benzoylecgonine, and cocaine metabolites in cannulated pressurized fetal sheep cerebral arteries.
Topics: Adrenergic alpha-Antagonists; Animals; Catheterization; Cerebral Arteries; Cocaine; Female; In Vitro Techniques; Pregnancy; Receptors, Adrenergic, alpha-1; Sheep; Vasoconstriction | 1994 |
Correlation of buccal mucosal transudate collected with a buccal swab and urine levels of cocaine.
Topics: Adult; Cocaine; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolic Clearance Rate; Mouth Mucosa; Narcotics; Pilot Projects; Substance Abuse Detection; Substance-Related Disorders | 1994 |
Cytotoxicity of the cocaine metabolite benzoylecgonine.
Topics: Animals; Cell Death; Cell Division; Cell Survival; Cocaine; DNA, Neoplasm; Glioma; Hybrid Cells; Mice; Narcotics; Neuroblastoma; Rats; Thymidine; Time Factors; Tritium; Tumor Cells, Cultured | 1994 |
Hemodynamic and cerebral blood flow effects of cocaine, cocaethylene and benzoylecgonine in conscious and anesthetized fetal lambs.
Topics: Amniotic Fluid; Anesthesia; Animals; Brain; Cerebrovascular Circulation; Cocaine; Consciousness; Female; Fetus; Hemodynamics; Hypertension; Neurotransmitter Uptake Inhibitors; Pregnancy; Pregnancy Complications, Cardiovascular; Sheep; Transducers; Ultrasonics; Uterus; Vascular Resistance | 1994 |
Analysis of cocaine and metabolites in brain using solid phase extraction and full-scanning gas chromatography/ion trap mass spectrometry.
Topics: Brain Chemistry; Cause of Death; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Neurotransmitter Uptake Inhibitors | 1994 |
Direct stopped-flow fluorescence polarization immunoassay of abused drugs and their metabolites in urine.
Topics: Amphetamine; Amphetamines; Calibration; Cannabinoids; Cocaine; Dronabinol; Fluorescence Polarization Immunoassay; Humans; Sensitivity and Specificity; Substance Abuse Detection; Temperature | 1994 |
The in vitro differential binding of benzoylecgonine to pigmented human hair samples.
Topics: Binding Sites; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Hair Color; Humans; In Vitro Techniques | 1994 |
Cocaine and metabolites in amniotic fluid may prolong fetal drug exposure.
Topics: Absorption; Amniotic Fluid; Animals; Cocaine; Deglutition; Female; Fetal Blood; Fetus; Meconium; Pregnancy; Sheep | 1994 |
Fatality due to fentanyl-cocaine intoxication resulting in a fall.
Topics: Abdominal Pain; Adult; Alcoholic Intoxication; Cocaine; Ethanol; Fentanyl; Humans; Male; Narcotics; Psychoses, Substance-Induced; Suicide | 1994 |
Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain.
Topics: Animals; Brain Chemistry; Carbachol; Cerebral Cortex; Cocaine; Female; Male; Muscarinic Antagonists; Neurotransmitter Uptake Inhibitors; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Rats; Rats, Sprague-Dawley | 1994 |
Cocaine selectively inhibits beta-adrenergic receptor binding in pregnant human myometrium.
Topics: Adrenergic beta-Antagonists; Binding, Competitive; Cocaine; Dihydroergotoxine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoproterenol; Least-Squares Analysis; Molecular Structure; Myometrium; Pindolol; Pregnancy; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1993 |
Frequency of cocaine and phencyclidine detection at a large urban public teaching hospital.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hospitals, Teaching; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phencyclidine; Substance Abuse Detection; Substance-Related Disorders; Urban Population | 1993 |
Gas chromatography/mass spectrometry for the determination of cocaine and benzoylecgonine over a wide concentration range (< 0.005-5 mg/dL) in postmortem blood.
Topics: Chromatography, Gas; Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Postmortem Changes; Regression Analysis; Reproducibility of Results | 1994 |
A comparison of meconium, maternal urine and neonatal urine for detection of maternal drug use during pregnancy.
Topics: Adult; Cocaine; Dronabinol; Female; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Infant, Newborn; Meconium; Methadone; Narcotics; New York City; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prevalence; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders | 1994 |
Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain.
Topics: Animals; Blood; Brain; Carbon Radioisotopes; Cocaine; Female; Fluorine Radioisotopes; Kinetics; Papio; Tomography, Emission-Computed | 1994 |
Cocaine exposure during pregnancy: improving assessment with radioimmunoassay of maternal hair.
Topics: Adult; Black or African American; Cocaine; Female; Hair; Humans; Interviews as Topic; Marital Status; Parity; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Radioimmunoassay; Self Disclosure; Substance Abuse Detection; Substance-Related Disorders; White People | 1994 |
Simultaneous determination of drugs of abuse (opiates, cocaine and amphetamine) in human hair by GC/MS and its application to a methadone treatment program.
Topics: Adult; Amphetamine; Calibration; Cocaine; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Male; Methadone; Morphine; Morphine Derivatives; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders | 1993 |
Cocaine and metabolites in the hair of ancient Peruvian coca leaf chewers.
Topics: Adult; Cocaine; Female; Hair; History, Ancient; Humans; Male; Middle Aged; Mummies; Peru; Substance Abuse Detection; Substance-Related Disorders | 1993 |
Interlaboratory comparison studies on the analysis of hair for drugs of abuse.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Morphine; Predictive Value of Tests; Radioimmunoassay; Reproducibility of Results; Substance Abuse Detection | 1993 |
The occurrence of cocaine, heroin and metabolites in hair of drug abusers.
Topics: Adult; Arm; Black People; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Head; Heroin; Humans; Illicit Drugs; Male; Substance Abuse Detection; White People | 1993 |
Decreased signal in Emit assays of drugs of abuse in urine after ingestion of aspirin: potential for false-negative results.
Topics: Aspirin; Cocaine; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; Glucosephosphate Dehydrogenase; Humans; Kinetics; Substance Abuse Detection | 1994 |
A method for simultaneous measurement of cocaine and nicotine in neonatal hair.
Topics: Cocaine; Cotinine; Female; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nicotine; Pregnancy; Radioimmunoassay; Reagent Kits, Diagnostic; Smoking | 1994 |
Hair analysis for drugs of abuse. VII. The incorporation rates of cocaine, benzoylecgonine and ecgonine methyl ester into rat hair and hydrolysis of cocaine in rat hair.
Topics: Animals; Cocaine; Drug Administration Schedule; Drug Stability; Gas Chromatography-Mass Spectrometry; Hair; Hydrolysis; Male; Rats; Rats, Inbred Strains | 1994 |
Transfer of cocaine and benzoylecgonine across the perfused human placental cotyledon.
Topics: Biological Transport; Cocaine; Female; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Narcotics; Perfusion; Placenta; Pregnancy | 1994 |
A massive, near-fatal cocaine intoxication in a body-stuffer. Case report and review of the literature.
Topics: Adult; Cocaine; Coma; Critical Care; Female; Humans; Liver Function Tests; Pancreatic Function Tests; Substance-Related Disorders | 1994 |
Reanalysis of forensic urine specimens containing benzoylecgonine and THC-COOH.
Topics: Bias; Cocaine; Cryopreservation; Dronabinol; Drug Stability; Evaluation Studies as Topic; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Substance Abuse Detection; Thermodynamics; Time Factors | 1994 |
The reliability of a solid-phase extraction system for the analysis of benzoylecgonine in urine.
Topics: Chromatography, Liquid; Cocaine; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reproducibility of Results | 1994 |
Human immunodeficiency virus type 1 replication in peripheral blood mononuclear cells in the presence of cocaine.
Topics: Adjuvants, Immunologic; Cells, Cultured; Cocaine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Monocytes; Substance-Related Disorders; T-Lymphocytes; Virus Replication | 1993 |
GC/MS quantitation of benzoylecgonine following liquid-liquid extraction of urine.
Topics: Chemistry Techniques, Analytical; Cocaine; Gas Chromatography-Mass Spectrometry; Humans | 1993 |
Cocaine and metabolite excretion in saliva under stimulated and nonstimulated conditions.
Topics: Adult; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Male; Saliva | 1993 |
m-Hydroxybenzoylecgonine: an important contributor to the immunoreactivity in assays for benzoylecgonine in meconium.
Topics: Artifacts; Cocaine; Humans; Immunoassay; Meconium | 1993 |
Solid-phase extraction and GC/MS quantitation of cocaine, ecgonine methyl ester, benzoylecgonine, and cocaethylene from meconium, whole blood, and plasma.
Topics: Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Meconium; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors | 1993 |
Evaluation of Emit II reagents on the Chem 1.
Topics: Barbiturates; Benzodiazepines; Cannabinoids; Chemistry Techniques, Analytical; Cocaine; Evaluation Studies as Topic; Humans; Indicators and Reagents; Narcotics; Phencyclidine; Reproducibility of Results | 1993 |
Effect of antibody density on the displacement kinetics of a flow immunoassay.
Topics: Animals; Antibodies, Monoclonal; Antigens; Cocaine; Immunoassay; Kinetics; Mice; Sepharose | 1994 |
Characterization of drug interferences caused by coelution of substances in gas chromatography/mass spectrometry confirmation of targeted drugs in full-scan and selected-ion monitoring modes.
Topics: Cocaine; Fluconazole; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Quality Control; Sensitivity and Specificity; Substance Abuse Detection | 1994 |
Long-term cocaine administration is not neurotoxic to cultured fetal mesencephalic dopamine neurons.
Topics: Animals; Cells, Cultured; Cocaine; Dopamine; Female; Fetus; Half-Life; Immunohistochemistry; Mesencephalon; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Effect of pre-enlistment testing on the confirmed drug-positive rate for Navy recruits.
Topics: Adolescent; Adult; Cocaine; Dronabinol; Ethanol; Female; Humans; Male; Military Personnel; Substance Abuse Detection; Time Factors; United States | 1993 |
Plasma cocaethylene concentrations in patients treated in the emergency room or trauma unit.
Topics: Adult; Cocaine; Emergency Service, Hospital; Ethanol; Female; Humans; Male; Osmolar Concentration; Trauma Centers | 1993 |
Cocaine and benzoylecgonine in saliva, serum, and urine.
Topics: Adolescent; Adult; Cocaine; Female; Humans; Male; Middle Aged; Radioimmunoassay; Saliva; Ultrafiltration | 1993 |
Analysis of phencyclidine and cocaine in human hair by tandem mass spectrometry.
Topics: Cocaine; Hair; Humans; Mass Spectrometry; Phencyclidine; Substance-Related Disorders | 1993 |
Detection of fetal cocaine exposure by analysis of amniotic fluid.
Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1993 |
Quantitation of benzoylnorecgonine and other cocaine metabolites in meconium by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cocaine; Female; Humans; Infant, Newborn; Meconium; Pregnancy; Substance-Related Disorders | 1993 |
Meconium testing for cocaine metabolite: prevalence, perceptions, and pitfalls.
Topics: Birth Weight; Cocaine; Female; Humans; Infant, Newborn; Meconium; Nurses; Pregnancy; Pregnancy Complications; Prenatal Care; Prevalence; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Suburban Population; Urban Population | 1993 |
Gastric alkalinization in the treatment of cocaine toxicity.
Topics: Animals; Biological Availability; Cocaine; Humans; Poisoning; Vasoconstriction | 1993 |
An automated preconcentration-derivatization system for the determination of cocaine and its metabolites in urine and illicit cocaine samples by gas chromatography/mass spectrometry.
Topics: Autoanalysis; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Narcotics; Substance Abuse Detection | 1996 |
In vivo pharmacokinetics and in vitro production of cocaethylene in pregnant guinea pigs.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Ethanol; Female; Mice; Microsomes, Liver; Pregnancy | 1996 |
Use of the USDT flow immunosensor for quantitation of benzoylecgonine in urine.
Topics: Antibody Specificity; Biosensing Techniques; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Sensitivity and Specificity | 1996 |
Elimination of fluconazole interference in gas chromatography/mass spectrometric confirmation of benzoylecgonine, the major metabolite of cocaine using pentafluoropropionyl derivative.
Topics: Cocaine; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; Fluconazole; Gas Chromatography-Mass Spectrometry; Humans | 1996 |
Traumatic ponto-medullary tear: a case report.
Topics: Adult; Basilar Artery; Cocaine; Ethanol; Forensic Medicine; Humans; Male; Medulla Oblongata; Pons; Rupture; Wounds, Nonpenetrating | 1996 |
Forensic immunochemistry.
Topics: Central Nervous System Agents; Cocaine; Enzyme-Linked Immunosorbent Assay; Forensic Medicine; Humans; Latex Fixation Tests; Methamphetamine; Morphine; Phenobarbital; Radioimmunoassay; Sensitivity and Specificity; Substance-Related Disorders | 1996 |
Gastric fluid analysis for determining gestational cocaine exposure.
Topics: Amniotic Fluid; Case-Control Studies; Cocaine; Female; Gastric Juice; Humans; Infant, Newborn; Meconium; Neonatal Screening; Pregnancy; Pregnancy Complications; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1996 |
Pregnancy enhances cocaine-induced stimulation of uterine contractions in the chronically instrumented rat.
Topics: Animals; Blood Pressure; Cocaine; Female; Heart Rate; Narcotics; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction | 1996 |
Evaluation of a point-of-care testing product for drugs of abuse; testing site is a key variable.
Topics: Cocaine; Dronabinol; Humans; Marijuana Abuse; Narcotics; Nursing Assessment; Opioid-Related Disorders; Patient Care Team; Point-of-Care Systems; Reagent Kits, Diagnostic; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 1995 |
Analysis of cocaine, benzoylecgonine, and cocaethylene in urine by HPLC with diode array detection.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Indicators and Reagents; Narcotics; Spectrophotometry, Ultraviolet; Substance Abuse Detection | 1996 |
Determination of cocaine, norcocaine, benzoylecgonine and ecgonine methyl ester in rat plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Gas Chromatography-Mass Spectrometry; Male; Rats; Rats, Sprague-Dawley; Regression Analysis | 1996 |
Cocaine and alcohol interactions in naive and alcohol-pretreated rats.
Topics: Alcoholism; Animals; Cocaine; Cross-Over Studies; Drug Interactions; Ethanol; Male; Rats; Rats, Wistar; Substance-Related Disorders | 1996 |
Enzyme-linked immunosorbent assay and latex agglutination inhibition reaction test for cocaine and benzoylecgonine in urine.
Topics: Animals; Cocaine; Enzyme Multiplied Immunoassay Technique; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; Latex Fixation Tests; Rabbits; Substance-Related Disorders | 1996 |
Quantitative versus qualitative urinalysis for benzoylecgonine in clinical trials for the assessment of cocaine use.
Topics: Cocaine; Humans; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome | 1995 |
Emergency department evaluation of a rapid assay for detection of cocaine metabolites in urine specimens.
Topics: Adolescent; Child; Child, Preschool; Cocaine; Emergency Service, Hospital; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Humans; Infant; Latex Fixation Tests; Prospective Studies; Substance Abuse Detection; Substance-Related Disorders | 1996 |
Comparison of HPLC and GC-MS for measurement cocaine and metabolites in human urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Urinalysis | 1996 |
One-step esterification of benzoylecgonine with dimethylformamide-dipropylacetal or dimethylformamide-diisopropylacetal in the presence of pyridine.
Topics: Acetals; Cocaine; Dimethylformamide; Esterification; Gas Chromatography-Mass Spectrometry; Humans; Pyridines; Stereoisomerism | 1996 |
Fetal cocaine exposure: analysis of vernix caseosa.
Topics: Chromatography, Gas; Cocaine; Female; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Reference Standards; Reproducibility of Results; Umbilical Cord; Vernix Caseosa | 1996 |
Analysis of cocaine and its metabolites from biological specimens using solid-phase extraction and positive ion chemical ionization mass spectrometry.
Topics: Calibration; Chromatography; Cocaine; Dopamine Uptake Inhibitors; Humans; Mass Spectrometry; Narcotics; Reference Standards; Reproducibility of Results; Tissue Distribution | 1995 |
A 5-year stability study of common illicit drugs in blood.
Topics: Amphetamine; Calibration; Cocaine; Codeine; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Longitudinal Studies; Methamphetamine; Morphine; Narcotics; Phencyclidine | 1995 |
Testing human hair and urine for anhydroecgonine methyl ester, a pyrolysis product of cocaine.
Topics: Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Indicators and Reagents; Trimethylsilyl Compounds | 1995 |
ONTRAK TESTCUP: a novel, on-site, multi-analyte screen for the detection of abused drugs.
Topics: Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Online Systems; Reference Standards; Reproducibility of Results; Substance Abuse Detection | 1995 |
Effects of cocaine on human platelet aggregation in vitro.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cocaine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Middle Aged; Narcotics; Platelet Aggregation; Thrombosis | 1996 |
Cocaine and metabolites in human graying hair: pigmentary relationship.
Topics: Adult; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Narcotics; Pigments, Biological; Substance-Related Disorders | 1996 |
Simplified quantitation of urinary benzoylecgonine in cocaine addiction research and for related pharmacotherapeutic trials.
Topics: Adolescent; Adult; Cocaine; Creatinine; Female; Fluorescence Polarization Immunoassay; Half-Life; Humans; Male; Metabolic Clearance Rate; Opioid-Related Disorders; Patient Compliance; Substance Abuse Detection | 1996 |
Cocaine and beta-adrenergic receptor function in pregnant myometrium.
Topics: Cocaine; Colforsin; Cyclic AMP; Female; Humans; In Vitro Techniques; Isoproterenol; Myometrium; Osmolar Concentration; Pregnancy; Receptors, Adrenergic, beta; Sodium Fluoride | 1996 |
Lowering cutoffs for initial and confirmation testing for cocaine and marijuana: large-scale study of effects on the rates of drug-positive results.
Topics: Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Reference Values; Sensitivity and Specificity; Substance Abuse Detection | 1997 |
Correlation between self-reported cocaine use and urine toxicology in an inner-city prenatal population.
Topics: Cocaine; Female; Health Behavior; Humans; Pregnancy; Prenatal Care; Prevalence; Self Disclosure; Substance-Related Disorders; Surveys and Questionnaires; United States; Urban Population | 1997 |
Assessment of an automated immunoassay based on kinetic interaction of microparticles in solution for determination of opiates and cocaine metabolite in urine.
Topics: Autoanalysis; Chromatography; Cocaine; Codeine; Cross Reactions; Humans; Immunoassay; Mass Spectrometry; Morphine; Morphine Derivatives; Narcotics; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity | 1997 |
Cocaine in hair, saliva, skin swabs, and urine of cocaine users' children.
Topics: Adolescent; Adult; Child; Child, Preschool; Cocaine; Environmental Exposure; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant; Narcotics; Saliva; Skin | 1996 |
Time course of cocaine in rabbit hair.
Topics: Animals; Cocaine; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Hair; Narcotics; Rabbits; Sensitivity and Specificity; Substance Abuse Detection | 1997 |
Determination of drug exposure using hair: application to child protective cases.
Topics: Adolescent; Adult; Amphetamines; Child; Child Abuse; Child, Preschool; Cocaine; Crack Cocaine; Environmental Exposure; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant; Male; Program Evaluation; Retrospective Studies; Substance Abuse Detection | 1997 |
Cocaine's lethality increases during late gestation in the rat: a study of "critical periods" of exposure.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Gestational Age; Mortality; Pregnancy; Pregnancy, Animal; Rats | 1997 |
Pharmacotherapy of schizophrenia patients with comorbid substance abuse.
Topics: Alcoholism; Antipsychotic Agents; Cocaine; Flupenthixol; Humans; Imipramine; Marijuana Abuse; Opioid-Related Disorders; Schizophrenia; Self Medication; Substance-Related Disorders; Tobacco Use Disorder | 1997 |
Determination of esterase-catalyzed cocaine metabolite formation by high-performance liquid chromatography with ultraviolet detection.
Topics: Animals; Benzoates; Benzoic Acid; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Cocaine; Cytosol; Esterases; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Narcotics; Spectrophotometry, Ultraviolet | 1997 |
Rapid liquid-liquid extraction of cocaine from urine for gas chromatographic-mass spectrometric analysis.
Topics: Alkanes; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Sensitivity and Specificity; Substance Abuse Detection | 1997 |
Liquid chromatographic analysis of cocaine and benzoylecgonine in plasma of traditional coca chewers from Bolivia during exercise.
Topics: Adult; Bolivia; Chromatography, High Pressure Liquid; Coca; Cocaine; Exercise; Humans; Indians, South American; Male; Middle Aged; Plants, Medicinal | 1997 |
Determination of cocaine and its metabolites in serum microsamples by high-performance liquid chromatography and its application to pharmacokinetics in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Male; Narcotics; Rats; Rats, Sprague-Dawley | 1997 |
Liquid chromatographic determination of cocaine, benzoylecgonine, and cocaethylene in whole blood and serum samples with diode-array detection.
Topics: Chromatography, Liquid; Cocaine; Humans; Molecular Structure | 1997 |
Brain and plasma levels of cocaine and benzoylecgonine in lead-expose and cadmium-exposed rats following acute or chronic intraperitoneal administration of cocaine.
Topics: Animals; Body Weight; Brain; Cadmium Chloride; Cocaine; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Eating; Injections, Intraperitoneal; Male; Narcotics; Nucleus Accumbens; Organometallic Compounds; Rats; Rats, Sprague-Dawley | 1997 |
Effect of drugs and cocaine metabolites on cocaine and cocaethylene binding to human serum in vitro.
Topics: Amphetamine; Analgesics, Opioid; Blood Proteins; Central Nervous System Stimulants; Cocaine; Codeine; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Methamphetamine; Morphine; Narcotics | 1997 |
Cocaine and benzoylecgonine in serum microsamples of intact and gonadectomized male and female Wistar rats.
Topics: Animals; Cocaine; Female; Male; Narcotics; Orchiectomy; Ovariectomy; Rats; Rats, Wistar; Sex Characteristics | 1997 |
Identification of unique cocaine metabolites and smoking by-products in postmortem blood and urine specimens.
Topics: Cocaine; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Postmortem Changes; Smoking; Substance-Related Disorders | 1997 |
Differential potencies of cocaine and its metabolites, cocaethylene and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Cocaine; Female; Fetus; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Somatostatin | 1997 |
Efficacy of two commercial products for altering urine drug test results.
Topics: Amphetamine; Cocaine; Codeine; Creatinine; Dronabinol; Drug and Narcotic Control; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Male; Radioimmunoassay; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 1997 |
Clinical utilization of the neonatal hair test for cocaine: a four-year experience in Toronto.
Topics: Cocaine; Cocaine-Related Disorders; Cohort Studies; Decision Trees; Drug Residues; Female; Hair; Humans; Infant, Newborn; Ontario; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Radioimmunoassay | 1997 |
Matrix and modifier effects in the supercritical fluid extraction of cocaine and benzoylecgonine from human hair.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Narcotics; Substance Abuse Detection | 1998 |
Molecular characteristics of cocaine-induced cardiomyopathy in rats.
Topics: Animals; Atrial Natriuretic Factor; Blotting, Northern; Cardiomyopathies; Cocaine; Collagen; Hemodynamics; Hormones; Male; Myocardium; Myosin Heavy Chains; Narcotics; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Relating cocaine blood concentrations to toxicity--an autopsy study of 99 cases.
Topics: Adult; Autopsy; Body Mass Index; Cause of Death; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Liver; Lung; Male; Myocardium; Organ Size; Regression Analysis; Retrospective Studies; Spleen; Wounds and Injuries | 1998 |
Comparison of immunoassays for semiquantitative measurement of benzoylecgonine in urine.
Topics: Antibody Specificity; Cocaine; Cross Reactions; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Substance Abuse Detection | 1997 |
Effect of recent cocaine use on the specificity of cardiac markers for diagnosis of acute myocardial infarction.
Topics: Biomarkers; Cocaine; Creatine Kinase; Cross-Sectional Studies; Electrocardiography; Female; Humans; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myoglobin; Radioimmunoassay; Risk Factors; Sensitivity and Specificity; Time Factors; Troponin I | 1998 |
Pharmacokinetics of cocaine and metabolites following intragastric administration to ten-day-old rat pups.
Topics: Administration, Oral; Animals; Animals, Newborn; Area Under Curve; Cocaine; Dietary Fats; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Rats; Rats, Sprague-Dawley | 1998 |
Correlation of urine and serum benzoylecgonine levels in pregnant women.
Topics: Cocaine; Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Pregnancy; Pregnancy Complications | 1997 |
Narrow-bore HPLC in combination with fluorescence and electrospray mass spectrometric detection for the analysis of cocaine and metabolites in human hair.
Topics: Chromatography, High Pressure Liquid; Cocaine; Hair; Humans; Mass Spectrometry; Reproducibility of Results; Spectrometry, Fluorescence; Substance-Related Disorders | 1998 |
Identification of cocaine analytes in fingernail and toenail specimens.
Topics: Adolescent; Adult; Cocaine; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Male; Middle Aged; Nails; Substance Abuse Detection | 1998 |
Cocaine infusion increases interferon-gamma and decreases interleukin-10 in cocaine-dependent subjects.
Topics: Adult; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Cocaine; Cocaine-Related Disorders; Cytokines; Female; Humans; Infusions, Intravenous; Interferon-gamma; Interleukin-10; Kinetics; Leukocyte Count; Leukocytes, Mononuclear; Lymphocyte Count; Male; Middle Aged; Phytohemagglutinins | 1998 |
Determination of five abused drugs in nitrite-adulterated urine by immunoassays and gas chromatography-mass spectrometry.
Topics: Amphetamine; Cocaine; Dronabinol; Drug Contamination; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Morphine; Nitrites; Phencyclidine; Substance Abuse Detection; Sulfites | 1998 |
Cocaine and alcohol interactions in the rat: contribution of cocaine metabolites to the pharmacological effects.
Topics: Algorithms; Animals; Area Under Curve; Biotransformation; Blood Pressure; Brain Chemistry; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Drug Interactions; Ethanol; Heart Rate; Injections, Intravenous; Male; Rats; Rats, Wistar | 1999 |
Analysis of urinary drugs of abuse by a multianalyte capillary electrophoretic immunoassay.
Topics: Amphetamines; Binding, Competitive; Cocaine; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Immunoassay; Methadone; Narcotics; Substance Abuse Detection | 1999 |
The disposition of cocaethylene in rat maternal, placental, and fetal compartments.
Topics: Amnion; Animals; Brain; Cocaine; Dopamine Uptake Inhibitors; Female; Fetus; Kinetics; Liver; Maternal-Fetal Exchange; Myocardium; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Estrous cycle differences in cocaine-induced stereotypic and locomotor behaviors in Fischer rats.
Topics: Animals; Biotransformation; Cocaine; Dopamine Uptake Inhibitors; Estrus; Female; Motor Activity; Rats; Rats, Inbred F344; Stereotyped Behavior | 1999 |
The comparative toxicity of cocaine and its metabolites in conscious rats.
Topics: Animals; Blood Pressure; Cocaine; Female; Heart Rate; Rats; Rats, Sprague-Dawley | 1999 |
Assessment of an automated solid phase competitive fluoroimmunoassay for benzoylecgonine in untreated urine.
Topics: Antibody Affinity; Binding, Competitive; Cocaine; Cross Reactions; Drug Stability; Fluoroimmunoassay; Humans; Polymethyl Methacrylate | 1999 |
Cocaethylene formation in rat, dog, and human hepatic microsomes.
Topics: Animals; Cocaine; Dogs; Dose-Response Relationship, Drug; Ethanol; Humans; Kinetics; Microsomes, Liver; Rats; Rats, Wistar | 1999 |
The interpretation of cocaine and benzoylecgonine concentrations in postmortem cases.
Topics: Adolescent; Adult; Autopsy; Cause of Death; Cocaine; Female; Humans; Male; Maryland; Middle Aged; Narcotics; Substance Abuse Detection | 1999 |
Aqueous phase hexylchloroformate derivatization and solid phase microextraction: determination of benzoylecgonine in urine by gas chromatography-quadrupole ion trap mass spectrometry.
Topics: Calibration; Cocaine; Formates; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Models, Chemical; Reproducibility of Results; Sensitivity and Specificity | 1999 |
Cocaine-induced increase in the permeability function of human vascular endothelial cell monolayers.
Topics: Actins; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cocaine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Electric Impedance; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Humans; Lipoproteins, LDL; Peroxidase; Umbilical Veins; Vasoconstrictor Agents | 1999 |
Broad spectrum drug identification directly from urine, using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Cocaine; Humans; Mass Spectrometry; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Urine | 1999 |
Cocaine pharmacodynamics after intravenous and oral administration in rats: relation to pharmacokinetics.
Topics: Administration, Oral; Animals; Biological Availability; Cocaine; Dopamine Uptake Inhibitors; Illicit Drugs; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule | 1999 |
Influence of infused catecholamines on the pharmacokinetics of cocaine and benzoylecgonine formation after bolus dose or continuous cocaine administration in the rat.
Topics: Animals; Catecholamines; Cocaine; Male; Rats; Rats, Sprague-Dawley | 1999 |
Effects of sex and gonadectomy on cocaine metabolism in the rat.
Topics: Animals; Brain; Cocaine; Female; Kinetics; Male; Motor Activity; Narcotics; Orchiectomy; Ovariectomy; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1999 |
Limited sex differences in response to "binge" smoked cocaine use in humans.
Topics: Adult; Behavior, Addictive; Biomarkers; Blood Pressure; Cocaine; Dopamine Uptake Inhibitors; Female; Heart Rate; Humans; Male; Self Administration; Sex Factors | 1999 |
Monitoring cocaine use in substance-abuse-treatment patients by sweat and urine testing.
Topics: Adolescent; Adult; Aged; Cocaine; Cocaine-Related Disorders; Enzyme Multiplied Immunoassay Technique; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Methadone; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Sweat | 1999 |
Determination of opiates and cocaine in hair as trimethylsilyl derivatives using gas chromatography-tandem mass spectrometry.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Humans; Indicators and Reagents; Morphine; Morphine Derivatives; Narcotics; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Trimethylsilyl Compounds | 1999 |
Cocaine absorption after application of a viscous cocaine-containing TAC solution.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Local; Child; Child, Preschool; Cocaine; Epinephrine; Female; Humans; Male; Skin Absorption; Tetracaine | 1999 |
Cocaine, norcocaine, ecgonine methylester and benzoylecgonine pharmacokinetics in the rat.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Half-Life; Male; Rats; Rats, Sprague-Dawley | 1999 |
A rapid reusable fiber optic biosensor for detecting cocaine metabolites in urine.
Topics: Antibodies, Monoclonal; Biosensing Techniques; Cocaine; Dopamine Uptake Inhibitors; Fiber Optic Technology; Fluorescence Polarization Immunoassay; Humans; Narcotics; Optical Fibers; Protein Binding; Reproducibility of Results; Sensitivity and Specificity; Urine | 1999 |
Prevalence of benzoylecgonine (a cocaine metabolite) in newborn infants by ZIP code, Georgia, February 22 through April 23, 1994.
Topics: Cocaine; Cocaine-Related Disorders; Georgia; Health Surveys; Humans; Infant, Newborn; Maps as Topic; Mass Screening; Mass Spectrometry; Prevalence; Radioimmunoassay | 1999 |
Level of in utero cocaine exposure and neonatal ultrasound findings.
Topics: Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Echoencephalography; Female; Fetus; Humans; Infant, Newborn; Intracranial Hemorrhages; Longitudinal Studies; Meconium; Odds Ratio; Pregnancy; Pregnancy Complications; Prospective Studies; Risk Factors | 1999 |
Cocaine and alcohol interactions in the rat: effect of cocaine and alcohol pretreatments on cocaine pharmacokinetics and pharmacodynamics.
Topics: Algorithms; Animals; Area Under Curve; Biotransformation; Blood Pressure; Brain Chemistry; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug Interactions; Ethanol; Heart Rate; Male; Models, Biological; Rats; Rats, Wistar | 1999 |
m-hydroxy benzoylecgonine recovery in fetal guinea pigs.
Topics: Amniotic Fluid; Animals; Cocaine; Female; Fetus; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Intestinal Mucosa; Intestines; Maternal-Fetal Exchange; Meconium; Metabolic Clearance Rate; Pregnancy; Tissue Distribution | 2000 |
Rapid confirmation/quantitation of cocaine and benzoylecgonine in urine utilizing high performance liquid chromatography and tandem mass spectrometry.
Topics: Adult; Chromatography, High Pressure Liquid; Cocaine; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Male; Mass Spectrometry; Middle Aged; Reproducibility of Results; Substance Abuse Detection | 2000 |
Validation of an ion-trap gas chromatographic-mass spectrometric method for the determination of cocaine and metabolites and cocaethylene in post mortem whole blood.
Topics: Biomarkers; Biotransformation; Calibration; Cocaine; Dopamine Uptake Inhibitors; Drug Synergism; Ethanol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reproducibility of Results; Risk Factors; Sensitivity and Specificity | 2000 |
The application of supercritical fluid extraction to cocaine and its metabolites in blood and urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Reproducibility of Results | 2000 |
Drug deposition in adipose tissue and skin: evidence for an alternative source of positive sweat patch tests.
Topics: Adipose Tissue; Cocaine; Cocaine-Related Disorders; Deuterium; Gas Chromatography-Mass Spectrometry; Heroin; Heroin Dependence; Humans; Illicit Drugs; Male; Morphine; Narcotics; Opioid-Related Disorders; Radiopharmaceuticals; Skin; Substance Abuse Detection; Sweat | 2000 |
Chronic continuous cocaine infusion in rats: effect on urine cocaine, ecgonine methylester and benzoylecgonine concentrations and bolus-dose cocaine pharmacokinetics.
Topics: Anesthetics, Local; Animals; Area Under Curve; Cocaine; Dose-Response Relationship, Drug; Half-Life; Infusions, Intravenous; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley | 2000 |
Sexual assault under benzodiazepine submission in a Paris suburb.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dronabinol; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunoassay; Lorazepam; Male; Morphine; Narcotics; Nitrazepam; Paris; Rape; Retrospective Studies; Substance-Related Disorders; Temazepam; Time Factors; Triazolam | 2000 |
Segmental analysis for cocaine and metabolites by HPLC in hair of suspected drug overdose cases.
Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Drug Overdose; Forensic Medicine; Hair; Humans | 2000 |
Verification of the drug history given by potential blood donors: results of drug screening that combines hair and urine analysis.
Topics: Adolescent; Adult; Amphetamines; Blood Donors; Cannabinoids; Cocaine; Communicable Diseases; Deception; Female; Germany; Hair; Humans; Male; Mass Screening; Medical History Taking; Morphine; Risk Factors; Substance Abuse Detection; Substance-Related Disorders; Surveys and Questionnaires; Truth Disclosure; Urine | 2000 |
A rapid, sensitive assay for cocaine and its metabolites in biological fluids using solid-phase extraction and high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Male; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Substance Abuse Detection | 2000 |
A gas chromatographic-positive ion chemical ionization-mass spectrometric method for determination of cocaine, benzoylecgonine, ecgonine methyl ester, and norcocaine in plasma: detection of norcocaine in plasma after oral administration of cocaine.
Topics: Administration, Oral; Cocaine; Gas Chromatography-Mass Spectrometry; Narcotics | 2000 |
Cocaine and its major metabolites in plasma and urine samples from patients in an urban emergency medicine setting.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Emergency Service, Hospital; Female; Gas Chromatography-Mass Spectrometry; Hospitals, Urban; Humans; Male; Middle Aged; Retrospective Studies; Substance Abuse Detection | 2000 |
Quantitation of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry.
Topics: Biotransformation; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection | 2000 |
Screening for stimulant use in adult emergency department seizure patients.
Topics: Adult; Amphetamine-Related Disorders; Cocaine; Cocaine-Related Disorders; Emergency Service, Hospital; Humans; Immunoenzyme Techniques; Mass Screening; Middle Aged; Missouri; Prospective Studies; Seizures; Single-Blind Method | 2000 |
Vendor differences in cocaine-induced behavioral activity and hormonal interactions in ovariectomized Fischer rats.
Topics: Animals; Behavior, Animal; Body Weight; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Estrogens; Female; Locomotion; Ovariectomy; Progesterone; Rats; Rats, Inbred F344; Species Specificity | 2001 |
Analysis of cocaethylene, benzoylecgonine and cocaine in human urine by high-performance thin-layer chromatography with ultraviolet detection: a comparison with high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cocaine; Sensitivity and Specificity; Ultraviolet Rays | 2001 |
The effect of gamma-vinyl-GABA on the consumption of concurrently available oral cocaine and ethanol in the rat.
Topics: Alcohol Drinking; Animals; Behavior, Addictive; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Self Administration; Vigabatrin | 2001 |
In vitro stability of cocaine in whole blood and plasma including ecgonine as a target analyte.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Plasma; Specimen Handling; Temperature | 2001 |
Pharmacokinetics of cocaine in maternal and fetal rhesus monkeys at mid-gestation.
Topics: Administration, Oral; Animals; Area Under Curve; Cocaine; Dopamine Uptake Inhibitors; Female; Gestational Age; Injections, Intravenous; Macaca mulatta; Maternal-Fetal Exchange; Pregnancy | 2001 |
Evaluation of immunoassays for semiquantitative detection of cocaine and metabolites or heroin and metabolites in extracts of sweat patches.
Topics: Cocaine; Heroin; Humans; Immunoenzyme Techniques; Morphine; Morphine Derivatives; Narcotics; Radioimmunoassay; Substance Abuse Detection; Sweat | 2001 |
Ecgonine is an important marker for cocaine use in inadequately preserved specimens.
Topics: Biomarkers; Cocaine; Cocaine-Related Disorders; Humans; Specimen Handling | 2001 |
Developing language skills of cocaine-exposed infants.
Topics: Analysis of Variance; Cocaine; Cocaine-Related Disorders; Female; Humans; Infant; Infant, Newborn; Language Development Disorders; Language Tests; Longitudinal Studies; Male; Meconium; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Regression Analysis; Statistics, Nonparametric | 2001 |
A survey of extraction techniques for drugs of abuse in urine.
Topics: Amphetamines; Chi-Square Distribution; Cocaine; Humans; Laboratories; Morphine; Narcotics; Quality Assurance, Health Care; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Surveys and Questionnaires; United Kingdom | 2001 |
Examination of postmortem fluids and tissues for the presence of methylecgonidine, ecgonidine, cocaine, and benzoylecgonine using solid-phase extraction and gas chromatography-mass spectrometry.
Topics: Body Fluids; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Postmortem Changes | 2001 |
Duration of positive urine for cocaine metabolite after ophthalmic administration: implications for testing patients with suspected Horner syndrome using ophthalmic cocaine.
Topics: Adult; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Horner Syndrome; Humans; Immunoenzyme Techniques; Male; Middle Aged; Ophthalmic Solutions; Osmolar Concentration; Sympathomimetics; Time Factors | 2001 |
Analysis of cocaine, benzoylecgonine, codeine, and morphine in hair by supercritical fluid extraction with carbon dioxide modified with methanol.
Topics: Carbon Dioxide; Chromatography; Cocaine; Codeine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methanol; Morphine; Reference Standards; Reproducibility of Results | 2001 |
Simultaneous pharmacokinetic modeling of cocaine and its metabolites, norcocaine and benzoylecgonine, after intravenous and oral administration in rats.
Topics: Administration, Oral; Animals; Cocaine; Injections, Intravenous; Male; Models, Biological; Rats; Rats, Sprague-Dawley | 2001 |
Preliminary studies of a fast screening method for cocaine and cocaine metabolites in urine using hollow fibre membrane solvent microextraction (HFMSME).
Topics: Adult; Chromatography, Gas; Cocaine; Half-Life; Humans; Microchemistry; Substance Abuse Detection | 2001 |
Analysis of cocaine, benzoylecgonine, ecogonine methyl ester, and ecgonine by high-pressure liquid chromatography-API mass spectrometry and application to a short-term degradation study of cocaine in plasma.
Topics: Artifacts; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Humans; Hydrolysis; Mass Spectrometry; Narcotics; Sensitivity and Specificity; Specimen Handling; Time Factors | 2001 |
Elimination of cocaine by pregnant sheep following single or multiple exposures.
Topics: Animals; Catheterization; Catheters, Indwelling; Cocaine; Dose-Response Relationship, Drug; Female; Fetus; Gas Chromatography-Mass Spectrometry; Gestational Age; Half-Life; Infusion Pumps; Injections, Intravenous; Maternal-Fetal Exchange; Metabolic Clearance Rate; Pregnancy; Pregnancy, Animal; Random Allocation; Sheep; Time Factors | 2001 |
A validated liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry method for quantitation of cocaine and benzoylecgonine in human plasma.
Topics: Adolescent; Adult; Atmospheric Pressure; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Injections, Intravenous; Mass Spectrometry; Reference Values; Sensitivity and Specificity; Specimen Handling; Temperature | 2001 |
Extraction of benzoylecgonine from urine specimens with Cerex Polycrom Clin II solid-phase extraction columns and the Speedisk Pressure Processor.
Topics: Automation; Chromatography, Ion Exchange; Cocaine; Cocaine-Related Disorders; Humans; Particle Size; Sensitivity and Specificity; Substance Abuse Detection | 2001 |
Rapid detection of benzoylecgonine in vitreous humor by enzyme immunoassay.
Topics: Autopsy; Cocaine; Cocaine-Related Disorders; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Sensitivity and Specificity; Vitreous Body | 2001 |
Urine analysis of laboratory personnel preparing cocaine training aids for a military working dog program.
Topics: Animals; Cocaine; Dogs; Dopamine Uptake Inhibitors; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Medical Laboratory Personnel; Military Personnel; Occupational Exposure; Specimen Handling; Substance Abuse Detection; Urinalysis; Workplace | 2001 |
Arteriovenous serum cocaine concentration difference after intravenous bolus injection and constant-rate infusions: relation to pharmacodynamic estimates in rats.
Topics: Animals; Area Under Curve; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Femoral Artery; Femoral Vein; Infusions, Intravenous; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology | 2001 |
Effects of cocaine and cocaine metabolites on cardiovascular function in squirrel monkeys.
Topics: Animals; Blood Pressure; Cocaine; Heart Rate; Models, Animal; Saimiri | 2001 |
Hair testing for drugs of abuse: evaluation of external cocaine contamination and risk of false positives.
Topics: Cocaine; Cocaine-Related Disorders; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection | 2001 |
Direct nose-brain transport of benzoylecgonine following intranasal administration in rats.
Topics: Administration, Intranasal; Animals; Biological Transport; Brain; Cocaine; Male; Nasal Cavity; Nasal Mucosa; Rats; Rats, Sprague-Dawley | 2001 |
Sex differences in cocaine-induced behavioral sensitization.
Topics: Animals; Behavior, Animal; Cocaine; Corticosterone; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intraperitoneal; Locomotion; Male; Rats; Rats, Inbred F344; Sex Factors; Stereotyped Behavior | 2001 |
Neonatal hair analysis for benzoylecgonine: a sensitive and semiquantitative biological marker for chronic gestational cocaine exposure.
Topics: Adult; Biomarkers; Birth Weight; Cocaine; Ethnicity; Female; Gestational Age; Hair; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Sensitivity and Specificity | 2002 |
Cocaine permeability and metabolism in colonic T-84 epithelial cell line.
Topics: Cell Line; Cell Membrane Permeability; Cocaine; Colon; Culture Media, Conditioned; Dose-Response Relationship, Drug; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Humans | 2001 |
Indicators of cocaine exposure and preterm birth.
Topics: Case-Control Studies; Cocaine; Cocaine-Related Disorders; Female; Hair; Humans; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications; Prevalence; Prospective Studies; Socioeconomic Factors | 2002 |
Confirmation of cocaine exposure by gas chromatography-mass spectrometry of urine extracts after methylation of benzoylecgonine.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Methylation; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2002 |
Endogenous gonadal hormones modulate behavioral and neurochemical responses to acute and chronic cocaine administration.
Topics: Animals; Behavior, Animal; Castration; Cocaine; Corticosterone; Drug Administration Schedule; Female; Gonadal Steroid Hormones; Hormones; Male; Motor Activity; Progesterone; Rats; Rats, Inbred F344; Sexual Behavior, Animal; Stereotyped Behavior; Testosterone | 2002 |
One-step liquid-liquid extraction of cocaine from urine samples for gas chromatographic analysis.
Topics: Chromatography, Gas; Cocaine; Confidence Intervals; Ether; Humans; Substance Abuse Detection | 2002 |
Simultaneous, quantitative determination of opiates, amphetamines, cocaine and benzoylecgonine in oral fluid by liquid chromatography quadrupole-time-of-flight mass spectrometry.
Topics: Amphetamines; Chromatography, Liquid; Cocaine; Humans; Narcotics; Reference Standards; Reproducibility of Results; Saliva; Spectrometry, Mass, Electrospray Ionization | 2002 |
Urinary elimination of cocaine metabolites in chronic cocaine users during cessation.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Female; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Male; Substance Abuse Detection | 2002 |
Evaluation of a solid-phase extraction method for benzoylecgonine urine analysis in a high-throughput forensic urine drug-testing laboratory.
Topics: Chemistry Techniques, Analytical; Chromatography, Ion Exchange; Cocaine; Cocaine-Related Disorders; Efficiency; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Substance Abuse Detection | 2002 |
The happy land homicides: 87 deaths due to smoke inhalation.
Topics: Adolescent; Adult; Burns; Carbon Monoxide; Carboxyhemoglobin; Cocaine; Cyanides; Ethanol; Female; Homicide; Humans; Male; Middle Aged; Smoke Inhalation Injury | 2003 |
High-performance liquid chromatographic determination of cocaine and benzoylecgonine by direct injection of human blood plasma sample into an alkyl-diol-silica (ADS) precolumn.
Topics: Chromatography, High Pressure Liquid; Cocaine; Equipment Design; Humans; Hydrogen-Ion Concentration; Reference Standards; Silicon Dioxide; Solvents; Substance-Related Disorders | 2003 |
Cocaine, benzoylecgonine, amphetamine, and N-acetylamphetamine binding to melanin subtypes.
Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Hair; Hair Color; Indoles; Mass Spectrometry; Melanins | 2003 |
The analysis of an intracerebral hematoma for drugs of abuse.
Topics: Central Nervous System Depressants; Cerebral Hemorrhage; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hematoma; Humans; Male; Middle Aged; Radioimmunoassay; Substance Abuse Detection | 2003 |
Cyclodextrin-modified micellar electrokinetic chromatography for the analysis of Esterom, a topical product consisting of hydrolyzed benzoylecgonine in propylene glycol.
Topics: Analgesics; Chromatography, Micellar Electrokinetic Capillary; Cocaine; Cyclodextrins; Electrophoresis, Capillary; Hydrolysis; Micelles; Stereoisomerism | 2003 |
Intoxication due to 1,4-butanediol.
Topics: Butylene Glycols; Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Hallucinogens; Humans; Illicit Drugs; Male; N-Methyl-3,4-methylenedioxyamphetamine | 2003 |
A fatal paramethoxymethamphetamine intoxication.
Topics: Adult; Amphetamine; Amphetamines; Central Nervous System Depressants; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Male; Methamphetamine | 2003 |
Prediction of impairment from urine benzoylecgonine concentrations.
Topics: Cocaine; Cocaine-Related Disorders; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Poisoning; Predictive Value of Tests; Substance Abuse Detection | 2003 |
Optimized conditions for simultaneous determination of opiates, cocaine and benzoylecgonine in hair samples by GC--MS.
Topics: Adolescent; Adult; Buffers; Case-Control Studies; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Narcotics; Phosphates; Substance-Related Disorders | 2003 |
Determination of cocaine, benzoylecgonine and cocaethylene in human hair by solid-phase microextraction and gas chromatography-mass spectrometry.
Topics: Cocaine; Hair; Humans; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Determination of the dermal penetration of esterom components using microdialysis sampling.
Topics: Administration, Topical; Animals; Benzoic Acid; Cocaine; Esterification; Female; Microdialysis; Pharmaceutical Solutions; Rats; Skin Absorption | 2003 |
Demographic, pathologic, and toxicological profiles of 127 decedents testing positive for ephedrine alkaloids.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Child, Preschool; Cocaine; Coronary Artery Disease; Dietary Supplements; Dopamine Uptake Inhibitors; Ephedrine; Fatty Liver; Female; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Morphine; Narcotics; Nephrosclerosis; Phenylpropanolamine; Racial Groups; Sex Distribution; Sympathomimetics; Wounds and Injuries | 2004 |
Analytic performance of immunoassays for drugs of abuse below established cutoff values.
Topics: Cocaine; Dextroamphetamine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Morphine; Narcotics; Phencyclidine; Predictive Value of Tests; Sensitivity and Specificity; Substance Abuse Detection | 2004 |
Detection and quantification of cocaine metabolites in urine samples from horses administered cocaine.
Topics: Administration, Sublingual; Animals; Cocaine; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Horses; Injections, Intravenous; Male; Sports; Substance Abuse Detection | 2003 |
Temporal effects of estrogen and progesterone on behavioral and endocrinological responses to acute cocaine administration.
Topics: Acute Disease; Animals; Behavior; Cocaine; Cocaine-Related Disorders; Corticosterone; Endocrine System; Estrogens; Female; Ovariectomy; Progesterone; Rats; Rats, Inbred F344; Time Factors | 2003 |
Cerebral cortical abnormalities seen in a non-human primate model of prenatal cocaine exposure are not related to vasoconstriction.
Topics: Animals; Cerebral Cortex; Cocaine; Female; Macaca mulatta; Male; Pregnancy; Prenatal Exposure Delayed Effects; Umbilical Arteries; Vasoconstriction | 2004 |
Pharmacokinetics of intravenous cocaine across the menstrual cycle in rhesus monkeys.
Topics: Animals; Biotransformation; Cocaine; Estradiol; Female; Injections, Intravenous; Luteinizing Hormone; Macaca mulatta; Menstrual Cycle; Progesterone | 2004 |
On-site testing of illicit drugs: the use of the drug-testing device "Toxiquick".
Topics: Amphetamine; Automobile Driving; Cannabinoids; Central Nervous System Stimulants; Cocaine; Dopamine Uptake Inhibitors; False Negative Reactions; False Positive Reactions; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Methadone; Narcotics; Reagent Strips; Saliva; Substance Abuse Detection | 2004 |
Monitoring of drugs and metabolites in body fluids by capillary electrophoresis with XeHg lamp-based and laser-induced fluorescence detection.
Topics: Albendazole; Aspirin; Body Fluids; Cocaine; Electrophoresis, Capillary; Lasers; N-Methyl-3,4-methylenedioxyamphetamine; Spectrometry, Fluorescence | 2004 |
Blue cohosh and perinatal stroke.
Topics: Adult; Caulophyllum; Cocaine; Female; Humans; Infant, Newborn; Phytotherapy; Plant Preparations; Pregnancy; Stroke; Vasoconstrictor Agents | 2004 |
Molecular recognition of cocaine by acetylcholinesterases for affinity purification and bio-sensing.
Topics: Acetylcholinesterase; Animals; Biosensing Techniques; Chromatography, Affinity; Coated Materials, Biocompatible; Cocaine; Drosophila; Electrochemistry; Electrophorus; Reproducibility of Results; Sensitivity and Specificity | 2004 |
HAIRVEQ: an external quality control scheme for drugs of abuse analysis in hair.
Topics: Automobile Driving; Clinical Laboratory Techniques; Cocaine; Dopamine Uptake Inhibitors; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Italy; Narcotics; National Health Programs; Quality Control; Reproducibility of Results; Spain; Substance Abuse Detection | 2004 |
Levels of cocaine and its metabolites in washed hair of demonstrated cocaine users and workplace subjects.
Topics: Adult; Aged; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Decontamination; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Hair; Humans; Male; Middle Aged; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Workplace | 2004 |
Screening for drugs of abuse in hair with ion spray LC-MS-MS.
Topics: Amphetamines; Anti-Anxiety Agents; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cotinine; Diazepam; Dopamine Uptake Inhibitors; Drug Overdose; Flunitrazepam; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morphine; Morphine Derivatives; Narcotics; Nicotine; Nicotinic Agonists; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2004 |
More on blue cohosh and perinatal stroke.
Topics: Caulophyllum; Cocaine; Female; Herbal Medicine; Humans; Infant, Newborn; Phytotherapy; Plant Preparations; Pregnancy; Stroke | 2004 |
Gender differences in cocaine pharmacokinetics in CF-1 mice.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cocaine; Female; Indicators and Reagents; Male; Mice; Sex Characteristics; Tissue Distribution | 2005 |
Cocaine-related fatalities in New South Wales, Australia 1993-2002.
Topics: Adolescent; Adult; Cocaine; Cocaine-Related Disorders; Death Certificates; Female; Humans; Male; Middle Aged; New South Wales | 2005 |
Determination of cocaine and benzoylecgonine by direct injection of human urine into a column-switching liquid chromatography system with diode-array detection.
Topics: Chromatography, Liquid; Cocaine; Flow Injection Analysis; Humans; Substance Abuse Detection | 2005 |
False-negative result for cocaine metabolites on a lateral-flow drug test slide corrected by dilution.
Topics: Cocaine; False Negative Reactions; Gas Chromatography-Mass Spectrometry; Humans; Substance Abuse Detection | 2005 |
Progesterone inhibits behavioral responses and estrogen increases corticosterone levels after acute cocaine administration.
Topics: Animals; Behavior, Animal; Cocaine; Corticosterone; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Estrogens; Estrous Cycle; Female; Hypothalamo-Hypophyseal System; Male; Motor Activity; Ovariectomy; Progesterone; Rats; Rats, Inbred F344; Stereotyped Behavior | 2005 |
Direct injection determination of benzoylecgonine, heroin, 6-monoacetylmorphine and morphine in serum by MLC.
Topics: Chromatography, Liquid; Cocaine; Heroin; Micelles; Morphine; Morphine Derivatives; Reproducibility of Results; Sensitivity and Specificity | 2005 |
Intravenous butyrylcholinesterase administration and plasma and brain levels of cocaine and metabolites in rats.
Topics: Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Cocaine; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Half-Life; Injections, Intraperitoneal; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents | 2005 |
Cocaine in surface waters: a new evidence-based tool to monitor community drug abuse.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Drainage, Sanitary; Environmental Monitoring; Epidemiological Monitoring; Evidence-Based Medicine; Humans; Italy; Mass Spectrometry; Residence Characteristics; Rivers; Urban Population; Urination; Waste Management | 2005 |
Validation of a method to detect cocaine and its metabolites in nails by gas chromatography-mass spectrometry.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Nails; Reproducibility of Results; Substance Abuse Detection | 2006 |
Time for tea, anyone?
Topics: Coca; Cocaine; Cocaine-Related Disorders; Doping in Sports; Humans; Sports; Substance Abuse Detection; Tea | 2005 |
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines | 2006 |
Surface-activated chemical ionization ion trap mass spectrometry in the analysis of drugs in dilute urine samples. Part II: analysis of morphine and other street drugs.
Topics: Cocaine; Codeine; Humans; Illicit Drugs; Mass Spectrometry; Morphine; Morphine Derivatives; Sensitivity and Specificity | 2005 |
Estrogen and progesterone affect cocaine pharmacokinetics in female rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Estrogens; Female; Mass Spectrometry; Motor Activity; Ovariectomy; Progesterone; Rats; Rats, Inbred F344; Time Factors | 2006 |
Application of pericardial fluid to the analysis of morphine (heroin) and cocaine in forensic toxicology.
Topics: Cocaine; Codeine; Dopamine Uptake Inhibitors; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Morphine; Narcotics; Pericardium; Postmortem Changes; Substance Abuse Detection | 2006 |
A high-performance thin-layer chromatographic technique to screen cocaine in urine samples.
Topics: Anesthetics, Local; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Forensic Medicine; Ganglionic Stimulants; Humans; Nicotine; Substance Abuse Detection | 2006 |
Relationships between concentrations of cocaine and its hydrolysates in peripheral blood, heart blood, vitreous humor and urine.
Topics: Cocaine; Dopamine Uptake Inhibitors; Forensic Pathology; Gas Chromatography-Mass Spectrometry; Humans; Postmortem Changes; Vitreous Body | 2006 |
Drug screening in urine by cloned enzyme donor immunoassay (CEDIA) and kinetic interaction of microparticles in solution (KIMS): a comparative study.
Topics: Amphetamines; Barbiturates; Benzodiazepines; Cannabinoids; Chromatography, Gas; Cocaine; Diagnostic Errors; Humans; Illicit Drugs; Immunoassay; Lysergic Acid Diethylamide; Methadone; Narcotics; Reagent Kits, Diagnostic; Substance Abuse Detection | 2006 |
Reliability of the cloned-enzyme donor immunoassay (CEDIA) for cocaine in human serum in the range between the detection limit and the cut-off.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Reproducibility of Results; Substance Abuse Detection | 2006 |
Effect of repeated cocaine administration on detection times in oral fluid and urine.
Topics: Adult; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Male; Saliva; Substance Abuse Detection | 2006 |
Interpreting the color effect of melanin on cocaine and benzoylecgonine assays for hair analysis: brown and black samples compared.
Topics: Cocaine; Dopamine Uptake Inhibitors; Forensic Toxicology; Hair; Hair Color; Humans; Melanins; ROC Curve; Substance Abuse Detection | 2007 |
Rapid analysis of benzoylecgonine in urine by fast gas chromatography-mass spectrometry.
Topics: Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Time Factors | 2006 |
Four years' experience in external proficiency testing programs for hair testing of drugs of abuse in Italy (HAIRVEQ) and comparison with the Society of Hair Testing program in 2005.
Topics: 3,4-Methylenedioxyamphetamine; Clinical Laboratory Techniques; Cocaine; Codeine; False Negative Reactions; False Positive Reactions; Forensic Medicine; Hair; Humans; Italy; Laboratories; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Opioid Peptides; Program Evaluation; Reproducibility of Results; Spain; Statistical Distributions; Substance Abuse Detection; Time Factors | 2007 |
Cocaine detection in maternal and neonatal hair: implications to fetal toxicology.
Topics: Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Hair; Humans; Infant; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Pregnancy; Substance Abuse Detection; Time Factors | 2007 |
Prevalence of gamma-hydroxybutyrate (GHB) in serum samples of amphetamine, metamphetamine and ecstasy impaired drivers.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Amphetamine-Related Disorders; Amphetamines; Automobile Driving; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Sodium Oxybate; Substance Abuse Detection | 2007 |
Pharmacokinetic profile of cocaine following intravenous administration in the female rabbit.
Topics: Animals; Area Under Curve; Central Nervous System Stimulants; Cocaine; Female; Half-Life; Injections, Intravenous; Models, Biological; Nonlinear Dynamics; Rabbits | 2007 |
Public health. Hard data on hard drugs, grabbed from the environment.
Topics: Cocaine; Cocaine-Related Disorders; Environmental Monitoring; Epidemiological Monitoring; Europe; Humans; Paper; Sewage; United States; Water | 2007 |
Chronic cocaine exposure in a toddler revealed by hair test.
Topics: Child Abuse; Child, Preschool; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Eating; Enzyme-Linked Immunosorbent Assay; Epilepsy, Tonic-Clonic; Female; Hair; Humans; Time Factors | 2007 |
Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluid.
Topics: Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Pericardial Effusion; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2007 |
Identification of cocaine-contaminated hair: perspectives on a paper.
Topics: Cocaine; Decontamination; Forensic Toxicology; Hair; Humans; Illicit Drugs; Research Design; Specimen Handling; Substance Abuse Detection | 2007 |
Broad-spectrum toxicological analysis of hair based on capillary zone electrophoresis-time-of-flight mass spectrometry.
Topics: Amphetamine; Cocaine; Electrophoresis, Capillary; Ephedrine; Forensic Medicine; Hair; Heroin; Humans; Illicit Drugs; Morphine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance Abuse Detection | 2007 |
Prevalence of cocaine use in ED patients with severe hypertension.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Emergency Service, Hospital; Hospitals, Teaching; Hospitals, Urban; Humans; Hypertension; Observation; Prevalence; Prospective Studies; Single-Blind Method | 2007 |
Prenatal cocaine and tobacco effects on children's language trajectories.
Topics: Adult; Child; Child, Preschool; Cocaine; Cocaine-Related Disorders; Female; Humans; Infant; Language Development; Language Development Disorders; Longitudinal Studies; Meconium; Pregnancy; Prenatal Exposure Delayed Effects; Smoking | 2007 |
Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals.
Topics: Chromatography, Liquid; Cities; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Ireland; Morphine; Pharmaceutical Preparations; Pyrrolidines; Residence Characteristics; Rivers; Solid Phase Extraction; Substance-Related Disorders; Tandem Mass Spectrometry; Temazepam; Waste Disposal, Fluid; Water Pollutants, Chemical | 2007 |
Surface-activated chemical ionization ion trap mass spectrometry for the analysis of cocaine and benzoylecgonine in hair after extraction and sample dilution.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection | 2007 |
Distribution of drugs of abuse within specific regions of the human brain.
Topics: Adolescent; Adult; Aged; Cerebellum; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Medulla Oblongata; Middle Aged; Morphine; Narcotics; Substance Abuse Detection; Substance-Related Disorders; Tissue Distribution | 2007 |
Confirmation by LC-MS of drugs in oral fluid obtained from roadside testing.
Topics: Amphetamines; Automobile Driving; Cocaine; Dopamine Uptake Inhibitors; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Predictive Value of Tests; Saliva; Sensitivity and Specificity; Substance Abuse Detection | 2007 |
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection | 2007 |
Cocaine-related deaths: an enigma still under investigation.
Topics: Brain; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Forensic Toxicology; Humans | 2008 |
Detection and quantification of low levels of benzoylecgonine in equine urine.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Horses; Substance Abuse Detection | 2008 |
Fatalities associated with fentanyl and co-administered cocaine or opiates.
Topics: Accidents; Adult; Aged; Aged, 80 and over; Cannabinoids; Cause of Death; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Drug Overdose; Ethanol; Female; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Narcotics; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders | 2007 |
Determination of cocaine, benzoylecgonine, cocaethylene and norcocaine in human hair using solid-phase extraction and liquid chromatography with tandem mass spectrometric detection.
Topics: Chromatography, Liquid; Cocaine; Hair; Humans; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2007 |
Commotio cordis as a result of a fight: report of a case considered to be imprudent homicide.
Topics: Adult; Cocaine; Death, Sudden, Cardiac; Dopamine Uptake Inhibitors; Forensic Medicine; Homicide; Humans; Male; Myocardium; Spain; Thoracic Injuries; Violence | 2008 |
Differentiation between drug use and environmental contamination when testing for drugs in hair.
Topics: Amphetamines; Cannabinoids; Cocaine; Dopamine Uptake Inhibitors; Drug Contamination; Drug Residues; Environmental Exposure; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Methanol; Narcotics; Solvents; Substance Abuse Detection; Substance-Related Disorders | 2008 |
Vitreous fluid quantification of opiates, cocaine, and benzoylecgonine: comparison of calibration curves in both blood and vitreous matrices with corresponding concentrations in blood.
Topics: Calibration; Cocaine; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; Male; Morphine Derivatives; Narcotics; Reproducibility of Results; Solid Phase Extraction; Substance Abuse Detection; Vitreous Body | 2007 |
Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination.
Topics: Cocaine; Discriminant Analysis; Dopamine Uptake Inhibitors; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection | 2008 |
On-site screening and GC-MS analysis of cocaine and heroin metabolites in body-packers urine.
Topics: Adult; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Male | 2008 |
Concentrations of cocaine and its major metabolite benzoylecgonine in blood samples from apprehended drivers in Sweden.
Topics: Adult; Age Distribution; Automobile Driving; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Sex Distribution; Substance Abuse Detection; Sweden | 2008 |
Elimination half-lives of benzoylecgonine and MDMA in an apprehended driver.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamine; Automobile Driving; Cocaine; Forensic Toxicology; Half-Life; Hallucinogens; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection | 2008 |
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Hyperkinesis; Mice; Mice, Knockout; Midazolam; Motor Activity; Protein Subunits; Receptors, GABA-A | 2008 |
Development of a bifunctional sensor using haptenized acetylcholinesterase and application for the detection of cocaine and organophosphates.
Topics: Acetylcholinesterase; Biosensing Techniques; Butyrylcholinesterase; Chlorpyrifos; Cholinesterase Inhibitors; Cocaine; Haptens; Immunoassay | 2008 |
Screening for cocaine metabolite fails to detect an intoxication.
Topics: Adult; Cocaine; Cross Reactions; Dopamine Uptake Inhibitors; Enzyme Multiplied Immunoassay Technique; False Negative Reactions; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Substance Abuse Detection; Vitreous Body | 2008 |
Prenatal cocaine exposure: drug and environmental effects at 9 years.
Topics: Case-Control Studies; Child; Child Development; Cocaine; Cocaine-Related Disorders; Female; Humans; Intelligence Tests; Male; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Schools | 2008 |
Development and validation of a solid-phase extraction gas chromatography-mass spectrometry method for the simultaneous quantification of methadone, heroin, cocaine and metabolites in sweat.
Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine Derivatives; Solid Phase Extraction; Sweat | 2008 |
Nails of newborns in monitoring drug exposure during pregnancy.
Topics: Caffeine; Central Nervous System Stimulants; Cocaine; Cotinine; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Maternal-Fetal Exchange; Methadone; Morphine; Nails; Narcotics; Nicotine; Nicotinic Agonists; Pregnancy; Smoking | 2008 |
Cocaine and opiate concentrations in hair from subjects in a heroin maintenance program in comparison to a methadone substituted group.
Topics: Cocaine; Codeine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Hair; Heroin; Heroin Dependence; Humans; Linear Models; Methadone; Narcotics; Substance Abuse Detection | 2009 |
A fast screening MALDI method for the detection of cocaine and its metabolites in hair.
Topics: Cocaine; Coumaric Acids; Hair; Humans; Methanol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance Abuse Detection; Temperature; Time Factors; Trifluoroacetic Acid | 2009 |
Cocaine and metabolites in waste and surface water across Belgium.
Topics: Belgium; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Drainage, Sanitary; Fresh Water; Humans; Narcotics; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2009 |
[Simultaneous analyses of cocaine and its metabolite benzoylecgonine in urine by LC-MS/MS].
Topics: Animals; Chromatography, Liquid; Cocaine; Forensic Toxicology; Guinea Pigs; Humans; Solid Phase Extraction; Tandem Mass Spectrometry | 2008 |
Development and validation of an analytical method for the simultaneous determination of cocaine and its main metabolite, benzoylecgonine, in human hair by gas chromatography/mass spectrometry.
Topics: Calibration; Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Indicators and Reagents; Reference Standards; Reproducibility of Results; Solvents; Substance Abuse Detection | 2008 |
An automated SPE/LC/MS/MS method for the analysis of cocaine and metabolites in whole blood.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2008 |
Determination of cocaine and its metabolites using cation-selective exhaustive injection and sweeping-MEKC.
Topics: Buffers; Cations; Chromatography, Micellar Electrokinetic Capillary; Cocaine; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Solvents; Time Factors | 2008 |
Molecular cloning and characterization of a single-chain variable fragment antibody specific for benzoylecgonine expressed in Escherichia coli.
Topics: Amino Acid Sequence; Antibodies; Antibody Specificity; Cloning, Molecular; Cocaine; Escherichia coli; Gene Expression; Hybridomas; Immunoglobulin Variable Region; Molecular Sequence Data | 2008 |
Multiclass analysis of illicit drugs in plasma and oral fluids by LC-MS/MS.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Body Fluids; Calibration; Chromatography, High Pressure Liquid; Cocaine; Dronabinol; Humans; Illicit Drugs; Ketamine; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2009 |
Screening for marijuana and cocaine abuse by immunoanalysis and gas chromatography.
Topics: Adolescent; Child; Cocaine; Cocaine-Related Disorders; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Marijuana Abuse; Mass Screening; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection; Surveys and Questionnaires; Urine; Young Adult | 2008 |
Complete automation of solid-phase extraction with subsequent liquid chromatography-tandem mass spectrometry for the quantification of benzoylecgonine, m-hydroxybenzoylecgonine, p-hydroxybenzoylecgonine, and norbenzoylecgonine in urine--application to a h
Topics: Automation; Chromatography, Liquid; Cocaine; Humans; Solid Phase Extraction; Tandem Mass Spectrometry | 2008 |
Validation of analysis of amphetamines, opiates, phencyclidine, cocaine, and benzoylecgonine in oral fluids by liquid chromatography-tandem mass spectrometry.
Topics: Amphetamines; Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Humans; Phencyclidine; Saliva; Tandem Mass Spectrometry | 2008 |
Imaging of latent fingerprints through the detection of drugs and metabolites.
Topics: Antibodies; Cannabis; Cocaine; Dermatoglyphics; Dronabinol; Humans; Magnetics; Methadone; Pharmaceutical Preparations; Quinolinium Compounds | 2008 |
Passive environmental exposure to cocaine in Canadian children.
Topics: Age Factors; Air Pollution, Indoor; Biomarkers; Canada; Caregivers; Child; Child Care; Child, Preschool; Cocaine; Cocaine-Related Disorders; Hair; Humans; Infant; Infant, Newborn; Inhalation Exposure; Narcotics; Smoke; Substance Abuse Detection | 2009 |
Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste- and surface water from Belgium and removal during wastewater treatment.
Topics: Belgium; Cocaine; Oxygen; Rivers; Surface Properties; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2009 |
Detection of drugs of forensic importance in postmortem bone.
Topics: Adult; Aged; Aged, 80 and over; Benzodiazepines; Bone and Bones; Cocaine; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Infant; Infant, Newborn; Male; Middle Aged; Narcotics; Pharmaceutical Preparations; Substance-Related Disorders | 2009 |
Simultaneous determination of morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in hair by liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Hair; Humans; Morphine; Morphine Derivatives; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2009 |
Determination of cocaine and benzoylecgonine in guinea pig's hair after a single dose administration by LC-MS/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Guinea Pigs; Hair; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysis.
Topics: Amphetamines; Cannabis; Child; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Infant, Newborn; Marijuana Abuse; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Smoking; Social Class; Spain; Substance Abuse Detection; Substance-Related Disorders | 2009 |
Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium.
Topics: Adolescent; Adult; Belgium; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Environmental Monitoring; Epidemiological Monitoring; Humans; Middle Aged; Narcotics; Substance Abuse Detection; Waste Disposal, Fluid; Water Pollutants, Chemical; Young Adult | 2009 |
Multi-center trial of baclofen for abstinence initiation in severe cocaine-dependent individuals.
Topics: Adult; Baclofen; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Combined Modality Therapy; Counseling; Dose-Response Relationship, Drug; Double-Blind Method; Educational Status; Employment; Female; GABA Agonists; Humans; Limbic System; Male; Middle Aged; Placebos; Racial Groups; Safety | 2009 |
Hair testing is superior to urine to disclose cocaine consumption in driver's licence regranting.
Topics: Adolescent; Adult; Automobile Driving; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Female; Forensic Toxicology; Hair; Humans; Italy; Licensure; Male; Middle Aged; Substance Abuse Detection; Urinalysis | 2009 |
Detection of cocaine and its metabolites in urine using solid phase extraction-ion mobility spectrometry with alternating least squares.
Topics: Cocaine; Dopamine Uptake Inhibitors; Forensic Toxicology; Humans; Mass Spectrometry; Models, Statistical; Solid Phase Microextraction; Substance Abuse Detection | 2009 |
Cocaine and heroin in waste water plants: a 1-year study in the city of Florence, Italy.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Illicit Drugs; Italy; Morphine; Narcotics; Seasons; Substance-Related Disorders; Waste Disposal, Fluid; Water | 2009 |
Optimization of a rapid microwave-assisted extraction method for the simultaneous determination of opiates, cocaine and their metabolites in human hair.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Hair; Humans; Illicit Drugs; Microwaves; Morphine; Morphine Derivatives; Narcotics | 2009 |
Pharmacokinetics of disappearance of cocaine from hair after discontinuation of drug use.
Topics: Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Forensic Toxicology; Hair; Half-Life; Humans; Male; Substance Abuse Detection | 2009 |
Brain biomarkers for identifying excited delirium as a cause of sudden death.
Topics: Adult; Amphetamines; Biomarkers; Blotting, Western; Brain; Brain Chemistry; Case-Control Studies; Cocaine; Death, Sudden; Delirium; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Forensic Genetics; Forensic Pathology; HSP70 Heat-Shock Proteins; Humans; Male; Polymerase Chain Reaction; Retrospective Studies; Transcription, Genetic; Violence | 2009 |
Simple method for determination of cocaine and main metabolites in urine by CE coupled to MS.
Topics: Cocaine; Electrophoresis, Capillary; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity | 2009 |
The spatial epidemiology of cocaine, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) use: a demonstration using a population measure of community drug load derived from municipal wastewater.
Topics: Cocaine; Environmental Monitoring; Epidemiological Monitoring; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Oregon; Rural Population; Substance Abuse Detection; Substance-Related Disorders; Urban Population; Waste Disposal, Fluid; Water Pollutants, Chemical | 2009 |
Detection of cocaine and benzoylecgonine in formalin fixed rat tissues.
Topics: Animals; Cocaine; Fixatives; Forensic Toxicology; Formaldehyde; Gas Chromatography-Mass Spectrometry; Male; Rats; Rats, Wistar; Substance Abuse Detection; Tissue Fixation | 2009 |
Predicted environmental concentrations of cocaine and benzoylecgonine in a model environmental system.
Topics: Cocaine; Environmental Monitoring; Environmental Pollutants; Forecasting; Models, Chemical | 2009 |
Stability of cocaine in formalin solution and fixed tissues.
Topics: Adult; Brain Chemistry; Cocaine; Dopamine Uptake Inhibitors; Drug Stability; Embalming; Fixatives; Forensic Toxicology; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male | 2009 |
Quantification of drugs of abuse and some stimulants in hair samples by liquid chromatography-electrospray ionization ion trap mass spectrometry.
Topics: Analgesics, Opioid; Chromatography, Liquid; Cocaine; Hair; Humans; Illicit Drugs; Limit of Detection; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection | 2009 |
A comparison of the validity of gas chromatography- mass spectrometry and liquid chromatography- tandem mass spectrometry analysis of urine samples for morphine, codeine, 6-acetylmorphine, and benzoylecgonine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Humans; Morphine Derivatives; Narcotics; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2009 |
Sensitive method for detection of cocaine and associated analytes by liquid chromatography-tandem mass spectrometry in urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2009 |
Parasailing fatalities in southwest Florida.
Topics: Adolescent; Adult; Central Nervous System Depressants; Cocaine; Dopamine Uptake Inhibitors; Equipment Failure; Ethanol; Female; Florida; Forensic Pathology; Humans; Male; Multiple Trauma; Recreation; Sports Equipment; Wind; Wounds, Nonpenetrating | 2009 |
Investigation of the identification point system adaptation in cocaine, benzoylecgonine and ecgonine methyl ester using a single quadrupole mass spectrometer.
Topics: Cocaine; Drug Stability; European Union; Guidelines as Topic; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity | 2009 |
On the electronic structure of cocaine and its metabolites.
Topics: Cocaine; Electrons; Hydrogen Bonding; Models, Molecular; Molecular Conformation | 2009 |
Evaluation of on-site oral fluid screening using Drugwipe-5(+), RapidSTAT and Drug Test 5000 for the detection of drugs of abuse in drivers.
Topics: Amphetamines; Automobile Driving; Cocaine; Dronabinol; Forensic Toxicology; Humans; Morphine; Narcotics; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders | 2010 |
The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Biological Availability; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cocaine; Dogs; Drug Interactions; Enzyme Inhibitors; Ethanol; Injections, Intravenous; Isoenzymes; Male; Metabolic Clearance Rate; Statistics as Topic | 2010 |
Analysis of hair after contamination with blood containing cocaine and blood containing benzoylecgonine.
Topics: Cocaine; Dopamine Uptake Inhibitors; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Immersion; Specimen Handling; Time Factors | 2010 |
Hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) determination of cocaine and its metabolites benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples.
Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Hair; Humans; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2010 |
Gas chromatography-mass spectrometry assay for the simultaneous quantification of drugs of abuse in human placenta at 12th week of gestation.
Topics: Abortion, Induced; Amphetamines; Cocaine; Cotinine; Dronabinol; Female; Forensic Toxicology; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Maternal Exposure; Maternal-Fetal Exchange; Methadone; Morphine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nicotine; Placenta; Pregnancy; Pregnancy Trimester, First; Specimen Handling; Substance Abuse Detection | 2010 |
Quantitation of cocaine, benzoylecgonine, ecgonine methyl ester, and cocaethylene in urine and blood using gas chromatography-mass spectrometry (GC-MS).
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Reference Standards; Reproducibility of Results; Solid Phase Extraction | 2010 |
Identification and quantitation of cocaine, benzoylecgonine, and cocaethylene in blood, serum, and plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS).
Topics: Acetonitriles; Chromatography, Liquid; Cocaine; Reference Standards; Reproducibility of Results; Solid Phase Extraction; Solvents; Tandem Mass Spectrometry | 2010 |
Detection and quantification of cocaine and benzoylecgonine in meconium using solid phase extraction and UPLC/MS/MS.
Topics: Chromatography, Liquid; Cocaine; Female; Humans; Infant, Newborn; Pregnancy; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2010 |
A molecular model for cocaine binding by the immunotherapeutic human/mouse chimeric monoclonal antibody 2E2.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens; Cocaine; Humans; Immunization; Immunoglobulin Variable Region; Mice; Models, Molecular; Molecular Sequence Data; Point Mutation; Protein Binding; Recombinant Fusion Proteins; Reproducibility of Results; Sequence Homology, Amino Acid; Substrate Specificity | 2010 |
Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine.
Topics: Adult; Biomarkers; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Male; Substance Abuse Detection | 2010 |
Roche DAT immunoassay: sensitivity and specificity testing for amphetamines, cocaine, and opiates in oral fluid.
Topics: Amphetamines; Cocaine; Codeine; Cross Reactions; False Negative Reactions; False Positive Reactions; Humans; Immunoassay; Methamphetamine; Morphine; Opiate Alkaloids; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Tandem Mass Spectrometry | 2010 |
Analysis of drugs of abuse in biofluids by low temperature plasma (LTP) ionization mass spectrometry.
Topics: Anesthetics, Local; Caffeine; Chromatography, High Pressure Liquid; Cocaine; Hair; Illicit Drugs; Reference Standards; Saliva; Spectrometry, Mass, Electrospray Ionization; Temperature | 2010 |
Estimation of illicit drugs consumption by wastewater analysis in Paris area (France).
Topics: Amphetamine; Buprenorphine; Chromatography, High Pressure Liquid; Cocaine; Humans; Illicit Drugs; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Paris; Sewage | 2010 |
Cocaine and benzoylecgonine concentrations in fluorinated plasma samples of drivers under suspicion of driving under influence.
Topics: Adult; Automobile Driving; Blood Specimen Collection; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Stability; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Germany; Humans; Male; Oxalates; Sodium Fluoride; Substance Abuse Detection | 2010 |
Analysis of cocaine and benzoylecgonine in urine by using multisyringe flow injection analysis-gas chromatography-mass spectrometry system.
Topics: Cocaine; Flow Injection Analysis; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Microwaves; Solid Phase Extraction | 2010 |
Label-free SERS detection of relevant bioanalytes on silver-coated carbon nanotubes: The case of cocaine.
Topics: Antibodies, Monoclonal; Cocaine; Models, Molecular; Nanotubes, Carbon; Silver; Spectrum Analysis, Raman | 2009 |
Illicit drugs in Canadian municipal wastewater and estimates of community drug use.
Topics: Amphetamine; Canada; Cities; Cocaine; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Solid Phase Extraction; Substance Abuse Detection; Substance-Related Disorders; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2010 |
Pharmacokinetics of cocaine and metabolites in human oral fluid and correlation with plasma concentrations after controlled administration.
Topics: Adult; Area Under Curve; Cocaine; Cocaine-Related Disorders; Female; Gas Chromatography-Mass Spectrometry; Gingival Crevicular Fluid; Half-Life; Humans; Injections, Subcutaneous; Male; Plasma; Saliva; Specimen Handling; Substance Abuse Detection | 2010 |
Analysis of cocaine and two metabolites in dried blood spots by liquid chromatography with fluorescence detection: a novel test for cocaine and alcohol intake.
Topics: Alcohol Drinking; Blood Specimen Collection; Chromatography, High Pressure Liquid; Cocaine; Desiccation; Ethanol; Female; Humans; Linear Models; Male; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Fluorescence; Substance Abuse Detection | 2010 |
Measurement of multiple drugs in urine, water, and on surfaces using fluorescence covalent microbead immunosorbent assay.
Topics: Caffeine; Cocaine; Dronabinol; Fluorescence; Humans; Illicit Drugs; Immunosorbent Techniques; Methamphetamine; Microspheres; Oxycodone; Substance Abuse Detection; Water | 2010 |
Development and validation of a gas chromatography/ion trap-mass spectrometry method for simultaneous quantification of cocaine and its metabolites benzoylecgonine and norcocaine: application to the study of cocaine metabolism in human primary cultured re
Topics: Acute Kidney Injury; Cells, Cultured; Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Kidney Tubules, Proximal; Models, Biological | 2010 |
Multiplexed detection of metabolites of narcotic drugs from a single latent fingermark.
Topics: Biological Assay; Cocaine; Dermatoglyphics; Humans; Immunoassay; Immunoconjugates; Magnetics; Morphine; Narcotics; Substance Abuse Detection; Time Factors | 2010 |
Fatal bronchial asthma with bilateral lung collapse.
Topics: Accidents, Traffic; Adult; Asthma; Bronchioles; Cannabinoids; Central Nervous System Depressants; Cocaine; Eosinophils; Ethanol; Fatal Outcome; Forensic Pathology; Humans; Lung; Macrophages; Male; Narcotics; Pulmonary Atelectasis; Pulmonary Emphysema; Thoracostomy | 2010 |
A fatally mistaken fruit juice drink: an unordinary way of cocaine intoxication.
Topics: Adult; Beverages; Citrus sinensis; Cocaine; Commerce; Crime; Forensic Pathology; Forensic Toxicology; Humans; Internet; Liver; Male; Myocardium; Narcotics; Vitreous Body | 2010 |
Distribution of concentrations of cocaine and its metabolites in hair collected postmortem from cases with diverse causes/circumstances of death.
Topics: Biotransformation; Central Nervous System Stimulants; Cocaine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection; Tissue Distribution | 2010 |
Differential glutamate AMPA-receptor plasticity in subpopulations of VTA neurons in the presence or absence of residual cocaine: implications for the development of addiction.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Dendrites; Dopamine Uptake Inhibitors; Dopaminergic Neurons; GABAergic Neurons; Male; Mice; Mice, Inbred C57BL; Multivesicular Bodies; Nerve Tissue Proteins; Neuronal Plasticity; Protein Subunits; Protein Transport; Random Allocation; Receptors, AMPA; Substance Withdrawal Syndrome; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2011 |
Determination of amphetamine-type stimulants, cocaine and ketamine in human hair by liquid chromatography/linear ion trap-Orbitrap hybrid mass spectrometry.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Chromatography, Liquid; Cocaine; Hair; Humans; Illicit Drugs; Ketamine; Limit of Detection; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry | 2011 |
Oral fluid results compared to self reports of recent cocaine and heroin use by methadone maintenance patients.
Topics: Cocaine; Cocaine-Related Disorders; Codeine; Heroin; Heroin Dependence; Humans; Methadone; Morphine; Morphine Derivatives; Narcotics; Opiate Substitution Treatment; Saliva; Self Report; Substance Abuse Detection | 2012 |
Population drug use in Australia: a wastewater analysis.
Topics: Australia; Cocaine; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Sewage; Substance-Related Disorders; Suburban Population; Time Factors; Urban Population | 2011 |
Fatal cocaine interactions: a review of cocaine-related deaths in Bexar County, Texas.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Central Nervous System Depressants; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Heroin; Histamine Antagonists; Humans; Male; Middle Aged; Narcotics; Retrospective Studies; Texas | 2011 |
Illicit drugs in alternative biological specimens: a case report.
Topics: Adult; Cocaine; Codeine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Kidney; Liver; Male; Morphine; Narcotics; Substance-Related Disorders; Vitreous Body | 2011 |
Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments.
Topics: Acetaminophen; Caffeine; Cocaine; Cotinine; Environmental Monitoring; Erythromycin; Halogenation; Illicit Drugs; Iohexol; Kinetics; Nicotine; Osmosis; Ozone; Pharmaceutical Preparations; Ultrafiltration; Water Pollutants, Chemical; Water Pollution, Chemical; Water Purification; Water Supply | 2011 |
Single hair cocaine consumption monitoring by mass spectrometric imaging.
Topics: Cocaine; Hair; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Direct surface plasmon resonance immunosensor for in situ detection of benzoylecgonine, the major cocaine metabolite.
Topics: Animals; Antibodies, Immobilized; Antibodies, Monoclonal; Binding, Competitive; Cocaine; Cocaine-Related Disorders; Equipment Reuse; Humans; Immunoassay; Lab-On-A-Chip Devices; Mice; Saliva; Surface Plasmon Resonance | 2011 |
Evaluation of the presence of drugs of abuse in tap waters.
Topics: Caffeine; Chromatography, High Pressure Liquid; Cocaine; Cotinine; Drinking Water; Environmental Monitoring; Illicit Drugs; Methadone; Nicotine; Pyrrolidines; Spectrometry, Mass, Electrospray Ionization | 2011 |
Employment. No proof that HIV medications caused man to fail drug test.
Topics: Anti-HIV Agents; Cocaine; HIV Infections; Humans; Male; New Jersey; Substance Abuse Detection | 2011 |
Marked decline in 3,4-methylenedioxymethamphetamine (MDMA) based on wastewater analysis.
Topics: Australia; Chromatography, High Pressure Liquid; Cocaine; Cross-Sectional Studies; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Population Surveillance; Saliva; Solid Phase Extraction; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry; Urban Health; Waste Disposal, Fluid; Water Supply | 2011 |
Aortic dissection and cocaine use.
Topics: Aorta; Aortic Aneurysm; Aortic Dissection; Cocaine; Cocaine-Related Disorders; Forensic Pathology; Forensic Toxicology; Humans; Male; Middle Aged; Myocardium; Narcotics | 2011 |
Toxicokinetics of cocaine and metabolites in a body-packer becoming symptomatic.
Topics: Adult; Cocaine; Crime; Electrocardiography; Forensic Toxicology; Humans; Intestinal Obstruction; Male; Narcotics; Tachycardia, Sinus | 2011 |
Assessment of total uncertainty in cocaine and benzoylecgonine wastewater load measurements.
Topics: Cocaine; Computer Simulation; Models, Chemical; Monte Carlo Method; Sewage; Stochastic Processes; Switzerland; Uncertainty; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2011 |
Screening and selective quantification of illicit drugs in wastewater by mixed-mode solid-phase extraction and quadrupole-time-of-flight liquid chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Databases, Factual; Dronabinol; Illicit Drugs; Sewage; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2012 |
The effect of sodium fluoride preservative and storage temperature on the stability of cocaine in horse blood, sheep vitreous and deer muscle.
Topics: Animals; Cocaine; Deer; Drug Stability; Fixatives; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Horses; Muscle, Skeletal; Narcotics; Regression Analysis; Sheep; Sodium Fluoride; Solid Phase Extraction; Specimen Handling; Temperature; Vitreous Body | 2012 |
The effect of sodium fluoride preservative and storage temperature on the stability of 6-acetylmorphine in horse blood, sheep vitreous and deer muscle.
Topics: Animals; Cocaine; Deer; Drug Stability; Fixatives; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Horses; Morphine Derivatives; Muscle, Skeletal; Narcotics; Regression Analysis; Sheep; Sodium Fluoride; Solid Phase Extraction; Specimen Handling; Temperature; Vitreous Body | 2012 |
Synthesis and characterization of molecularly imprinted polymers for the selective extraction of cocaine and its metabolite benzoylecgonine from hair extract before LC-MS analysis.
Topics: Acetonitriles; Chemical Fractionation; Chromatography, Liquid; Cocaine; Cross-Linking Reagents; Hair; Humans; Light; Limit of Detection; Methacrylates; Molecular Imprinting; Photochemical Processes; Polymerization; Polymers; Tandem Mass Spectrometry | 2012 |
Chromatographic determination of drugs of abuse in vitreous humor using solid-phase extraction.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Humans; Illicit Drugs; Morphine Derivatives; Pyrrolidines; Reproducibility of Results; Solid Phase Extraction; Vitreous Body | 2013 |
Dilute and shoot: analysis of drugs of abuse using selected reaction monitoring for quantification and full scan product ion spectra for identification.
Topics: Chromatography, Liquid; Cocaine; Humans; Hydrocodone; Hydromorphone; Ions; Methamphetamine; Reproducibility of Results; Signal-To-Noise Ratio; Substance Abuse Detection; Tandem Mass Spectrometry | 2012 |
Analytical evaluation of four on-site oral fluid drug testing devices.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Dronabinol; Humans; Methamphetamine; Morphine Derivatives; Reproducibility of Results; Saliva; Sensitivity and Specificity; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2012 |
Formation of benzoylecgonine isopropyl ester following solid-phase extraction.
Topics: Ammonium Hydroxide; Cocaine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydroxides; Liquid-Liquid Extraction; Methanol; Reproducibility of Results; Solid Phase Extraction; Solvents | 2012 |
Permeation and metabolism of cocaine in the nasal mucosa.
Topics: 2,4-Dinitrophenol; Animals; Biological Transport; Cattle; Cocaine; Epithelium; Nasal Mucosa; Permeability | 2012 |
Hair testing for cocaine and metabolites by GC/MS: criteria to quantitatively assess cocaine use.
Topics: Cocaine; Female; Forensic Pathology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Limit of Detection; Male; Reproducibility of Results; Solid Phase Extraction | 2013 |
Temporal analysis of the cocaine metabolite benzoylecgonine in wastewater to estimate community drug use.
Topics: Cocaine; Cocaine-Related Disorders; Epidemiological Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Solid Phase Extraction; Texas; Wastewater | 2012 |
Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS.
Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Drug Contamination; Forensic Pathology; Heroin; Humans; Illicit Drugs; Morphine; Morphine Derivatives; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Xylazine | 2012 |
Evaluation of two enzyme immunoassays for the detection of the cocaine metabolite benzoylecgonine in 1,398 urine specimens.
Topics: Cocaine; False Negative Reactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Reproducibility of Results; Sensitivity and Specificity; Substance Abuse Detection | 2012 |
The effects of benzoylecgonine, oxytocin, ritodrine and atosiban on the contractility of myometrium. An experimental study.
Topics: Animals; Cocaine; Drug Antagonism; Female; Oxytocin; Pregnancy; Rats; Rats, Wistar; Ritodrine; Tocolytic Agents; Uterine Contraction; Vasotocin | 2012 |
Cocaine and metabolites by LC-MS/MS.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Substance Abuse Detection; Tandem Mass Spectrometry | 2012 |
Drugs of abuse in wastewater and suspended particulate matter--further developments in sewage epidemiology.
Topics: Cocaine; Czech Republic; Environmental Monitoring; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Pyrrolidines; Sewage; Substance-Related Disorders; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2012 |
Probing cocaine-antibody interactions in buffer and human serum.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antibody Affinity; Binding, Competitive; Calorimetry; Cattle; Cocaine; Cocaine-Related Disorders; Humans; Immobilized Proteins; Immunotherapy; Kinetics; Mice; Protein Binding; Serum; Serum Albumin; Serum Albumin, Bovine; Surface Plasmon Resonance | 2012 |
Cocaine in sudden and unexpected death: a review of 49 post-mortem cases.
Topics: Adolescent; Adult; Aged; Amphetamines; Analgesics, Opioid; Australia; Benzodiazepines; Cause of Death; Central Nervous System Depressants; Cocaine; Death, Sudden; Ethanol; Fatty Liver; Female; Forensic Pathology; Forensic Toxicology; Heart Diseases; Hepatitis C; Humans; Male; Middle Aged; Narcotics; Young Adult | 2013 |
A redox proteomic investigation of oxidative stress caused by benzoylecgonine in the freshwater bivalve Dreissena polymorpha.
Topics: Animals; Cocaine; Dreissena; Humans; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Proteins; Proteomics; Sulfhydryl Compounds; Water Pollutants, Chemical | 2013 |
Evaluation of pre-analysis loss of dependent drugs in wastewater: stability and binding assessments.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Codeine; Cotinine; Drug Stability; Illicit Drugs; Liquid-Liquid Extraction; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2013 |
Development and validation of two LC-MS/MS methods for the detection and quantification of amphetamines, designer amphetamines, benzoylecgonine, benzodiazepines, opiates, and opioids in urine using turbulent flow chromatography.
Topics: Amphetamines; Analgesics, Opioid; Automobile Driving; Benzodiazepines; Calibration; Chemistry Techniques, Analytical; Chromatography; Chromatography, Liquid; Cocaine; Germany; Humans; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors; Urinalysis | 2013 |
Cocaethylene as a biomarker to predict heavy alcohol exposure among cocaine users.
Topics: Alcohol Drinking; Biomarkers; Cocaine; Enzyme-Linked Immunosorbent Assay; Ethanol; Fatty Acids; Female; Fetal Alcohol Spectrum Disorders; Gas Chromatography-Mass Spectrometry; Hair; Humans; Predictive Value of Tests; Pregnancy; Sensitivity and Specificity; Solid Phase Microextraction; Substance Abuse Detection | 2012 |
Investigation of degradation products of cocaine and benzoylecgonine in the aquatic environment.
Topics: Chromatography, High Pressure Liquid; Cocaine; Mass Spectrometry; Solid Phase Extraction; Water Pollutants, Chemical | 2013 |
Evaluation of uncertainties associated with the determination of community drug use through the measurement of sewage drug biomarkers.
Topics: Biomarkers; Cocaine; Humans; Population Density; Sewage; Solid Phase Extraction; Substance-Related Disorders; Surveys and Questionnaires; Uncertainty; Water Pollutants, Chemical | 2013 |
Sub-lethal effects caused by the cocaine metabolite benzoylecgonine to the freshwater mussel Dreissena polymorpha.
Topics: Animals; Antioxidants; Biomarkers; Catalase; Cocaine; Dreissena; Fresh Water; Glutathione Transferase; Hemocytes; Lethal Dose 50; Micronucleus Tests; Oxidative Stress; Superoxide Dismutase; Water Pollutants, Chemical | 2013 |
Analysis of skeletal muscle has potential value in the assessment of cocaine-related deaths.
Topics: Adolescent; Adult; Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Myocardium; Narcotics; Quadriceps Muscle; Substance Abuse Detection; Vitreous Body; Young Adult | 2013 |
Determination of cocaine, cocaine metabolites and cannabinoids in single hairs by MALDI Fourier transform mass spectrometry--preliminary results.
Topics: Cannabinoids; Cocaine; Coumaric Acids; Fourier Analysis; Hair; Humans; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
LC/MS/MS evaluation of cocaine and its metabolites in different brain areas, peripheral organs and plasma in cocaine self-administering rats.
Topics: Animals; Biotransformation; Brain; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Half-Life; Injections, Intravenous; Kidney; Liver; Male; Metabolic Clearance Rate; Myocardium; Rats; Rats, Wistar; Reproducibility of Results; Self Administration; Substance Withdrawal Syndrome; Tandem Mass Spectrometry; Tissue Distribution | 2012 |
Biotransformation kinetics and sorption of cocaine and its metabolites and the factors influencing their estimation in wastewater.
Topics: Adsorption; Aerobiosis; Anaerobiosis; Biodegradation, Environmental; Biomarkers; Biotransformation; Cocaine; Computer Simulation; Humans; Kinetics; Wastewater; Water Pollutants, Chemical | 2013 |
Cocaine postmortem distribution in three brain structures: a comparison with whole blood and vitreous humour.
Topics: Adolescent; Adult; Analysis of Variance; Basal Ganglia; Cerebellum; Cocaine; Drug Overdose; Female; Forensic Toxicology; Humans; Male; Middle Aged; Narcotics; Postmortem Changes; Prefrontal Cortex; Vitreous Body; Young Adult | 2013 |
Adolescents are more vulnerable to cocaine addiction: behavioral and electrophysiological evidence.
Topics: Action Potentials; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Quinpirole; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Self Administration; Time Factors; Ventral Tegmental Area | 2013 |
Cocaine and specific cocaine metabolites induce von Willebrand factor release from endothelial cells in a tissue-specific manner.
Topics: Brain; Cells, Cultured; Cocaine; Coronary Vessels; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; P-Selectin; Sensitivity and Specificity; Thrombosis; von Willebrand Factor | 2013 |
Peptides trapping cocaine: docking simulation and experimental screening by solid phase extraction followed by liquid chromatography mass spectrometry in plasma samples.
Topics: Chromatography, Liquid; Cocaine; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Peptides; Protein Binding; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2013 |
[Passive cocaine inhalation by a 25-month-old child].
Topics: Bacterial Infections; Child, Preschool; Cocaine; Developmental Disabilities; Diagnosis, Differential; Female; Hair; Humans; Psychomotor Disorders; Seizures, Febrile; Time Factors | 2013 |
Concentrations of drugs determined in blood samples collected from suspected drugged drivers in England and Wales.
Topics: Adolescent; Adult; Amphetamine; Automobile Driving; Central Nervous System Depressants; Chromatography, Liquid; Cocaine; Diazepam; England; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Ketamine; Male; Methadone; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Nordazepam; Sodium Oxybate; Substance Abuse Detection; Substance-Related Disorders; Wales; Young Adult | 2013 |
Extending the dynamic range of the ion trap by differential mobility filtration.
Topics: Cocaine; Equipment Design; Humans; Ions; Tandem Mass Spectrometry | 2013 |
First evidence of protein profile alteration due to the main cocaine metabolite (benzoylecgonine) in a freshwater biological model.
Topics: Animals; Calcium; Cocaine; Dreissena; Fresh Water; Gills; Homeostasis; Oxidative Stress; Transcriptome; Water Pollutants, Chemical | 2013 |
Adverse effects induced by ecgonine methyl ester to the zebra mussel: a comparison with the benzoylecgonine.
Topics: Animals; Biomarkers; Catalase; Cocaine; DNA Fragmentation; Dreissena; Glutathione Peroxidase; Glutathione Transferase; Lipid Peroxidation; Superoxide Dismutase | 2013 |
Analysis of cocaine and nicotine metabolites in wastewater by liquid chromatography-tandem mass spectrometry. Cross abuse index patterns on a major community.
Topics: Chromatography, Liquid; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Nicotine; Solid Phase Extraction; Substance-Related Disorders; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2014 |
Estimating daily and diurnal variations of illicit drug use in Hong Kong: a pilot study of using wastewater analysis in an Asian metropolitan city.
Topics: Chromatography, Liquid; Cocaine; Hong Kong; Humans; Ketamine; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Narcotics; Pilot Projects; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry; Time Factors; Urban Population; Wastewater | 2013 |
Challenges of surveying wastewater drug loads of small populations and generalizable aspects on optimizing monitoring design.
Topics: Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Humans; Seasons; Tandem Mass Spectrometry; Wastewater; Weather | 2014 |
Stability of cocaine and its metabolites in municipal wastewater--the case for using metabolite consolidation to monitor cocaine utilization.
Topics: Cocaine; Drug Utilization; Environmental Monitoring; Hydrogen-Ion Concentration; Hydrolysis; Sewage; Wastewater; Water Pollutants, Chemical | 2014 |
Development and validation of a single LC-MS/MS assay following SPE for simultaneous hair analysis of amphetamines, opiates, cocaine and metabolites.
Topics: Amphetamines; Analgesics, Opioid; Chromatography, Liquid; Cocaine; Forensic Toxicology; Hair; Humans; Limit of Detection; Male; Narcotics; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2014 |
Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Female; Immunotherapy, Active; Macaca mulatta; Vaccination; Vaccines | 2014 |
Determination of cocaine and its major metabolite benzoylecgonine in several matrices obtained from deceased individuals with presumed drug consumption prior to death.
Topics: Adult; Autopsy; Cocaine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Solid Phase Extraction; Substance Abuse Detection | 2014 |
Association between travel length and drug use among Brazilian truck drivers.
Topics: Adult; Amphetamine-Related Disorders; Amphetamines; Automobile Driving; Brazil; Cocaine; Cocaine-Related Disorders; Dronabinol; Female; Humans; Male; Marijuana Abuse; Middle Aged; Motor Vehicles | 2015 |
A study on photodegradation of methadone, EDDP, and other drugs of abuse in hair exposed to controlled UVB radiation.
Topics: Analgesics, Opioid; Cocaine; Hair; Humans; Methadone; Morphine; Morphine Derivatives; Photolysis; Pyrrolidines; Substance Abuse Detection; Ultraviolet Rays | 2014 |
Population normalization with ammonium in wastewater-based epidemiology: application to illicit drug monitoring.
Topics: Ammonium Compounds; Cocaine; Drug Monitoring; Epidemiologic Methods; Humans; Illicit Drugs; Population Density; Time Factors; Wastewater | 2014 |
[Recurrent neutropenia due to adulterated cocaine].
Topics: Adult; Agranulocytosis; Cocaine; Cocaine-Related Disorders; Drug Contamination; Humans; Levamisole; Male; Neutropenia; Recurrence | 2014 |
Analysis of drugs of abuse in human plasma by dispersive liquid-liquid microextraction and high-performance liquid chromatography.
Topics: Analytic Sample Preparation Methods; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cocaine; Humans; Hydrogen-Ion Concentration; Illicit Drugs; Limit of Detection; Liquid Phase Microextraction; Methadone; Morphine; Morphine Derivatives; Opiate Substitution Treatment; Photometry; Reproducibility of Results; Solubility; Spectrophotometry, Ultraviolet; Substance Abuse Detection; Substance-Related Disorders; Ultrasonics | 2015 |
Wastewater testing compared with random urinalyses for the surveillance of illicit drug use in prisons.
Topics: Cocaine; Humans; Illicit Drugs; Methamphetamine; Prisoners; Prisons; Substance Abuse Detection; Urinalysis; Wastewater | 2016 |
Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.
Topics: Acetaminophen; Acetone; Adolescent; Adult; Aged; Chromatography, Liquid; Coca; Cocaine; Cocaine-Related Disorders; Drug and Narcotic Control; Drug Contamination; Female; Forensic Toxicology; Hair; Humans; Levamisole; Lidocaine; Male; Mass Spectrometry; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Tea | 2015 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Evaluation of laser diode thermal desorption-tandem mass spectrometry (LDTD-MS-MS) in forensic toxicology.
Topics: Calibration; Chromatography, Liquid; Cocaine; Evaluation Studies as Topic; Forensic Toxicology; Humans; Limit of Detection; Phencyclidine; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2014 |
Case management in a DUI lab: effect on drugs reported.
Topics: Automobile Driving; Barbiturates; Benzodiazepines; Carisoprodol; Cocaine; Dronabinol; Ethanol; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Methamphetamine; Oxycodone; Oxymorphone; Substance Abuse Detection | 2014 |
Application of drug testing using exhaled breath for compliance monitoring of drug addicts in treatment.
Topics: Adolescent; Adult; Aged; Amphetamines; Breath Tests; Buprenorphine; Cocaine; Drug Users; Exhalation; Female; Humans; Male; Methadone; Methamphetamine; Middle Aged; Morphine; Morphine Derivatives; Patient Compliance; Substance Abuse Detection; Young Adult | 2015 |
Magnetically optimized SERS assay for rapid detection of trace drug-related biomarkers in saliva and fingerprints.
Topics: Biomarkers; Cocaine; Cotinine; Dermatoglyphics; Gold; Humans; Limit of Detection; Magnets; Metal Nanoparticles; Phytic Acid; Saliva; Spectrum Analysis, Raman; Surface Plasmon Resonance | 2015 |
Realistic mixture of illicit drugs impaired the oxidative status of the zebra mussel (Dreissena polymorpha).
Topics: Animals; Antioxidants; Cocaine; Dreissena; Fresh Water; Glutathione Transferase; Illicit Drugs; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Water Pollutants, Chemical | 2015 |
Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Chemical Phenomena; Cocaine; Disulfides; Fluorometry; Glucans; Humans; Immunoglobulin Fab Fragments; Protein Binding; Recombinant Proteins; Static Electricity | 2015 |
Economical synthesis of 13C-labeled opiates, cocaine derivatives and selected urinary metabolites by derivatization of the natural products.
Topics: Analgesics, Opioid; Biological Products; Carbon-13 Magnetic Resonance Spectroscopy; Cocaine; Codeine; Heroin; Humans; Molecular Structure; Morphine; Morphine Derivatives; Substance Abuse Detection; Urinalysis | 2015 |
The effect of chronic renal failure on the benzoylecgonine blood level: a case report.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Coronary Artery Disease; Forensic Toxicology; Humans; Hypertension; Kidney Failure, Chronic; Male; Narcotics; Prisoners | 2015 |
Cardiac depression induced by cocaine or cocaethylene is alleviated by lipid emulsion more effectively than by sulfobutylether-β-cyclodextrin.
Topics: Animals; Arrhythmias, Cardiac; beta-Cyclodextrins; Bupivacaine; Cardiotoxicity; Cocaine; Coronary Circulation; Depression, Chemical; Fat Emulsions, Intravenous; Heart; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley | 2015 |
The first application of wastewater-based drug epidemiology in five South Korean cities.
Topics: Amphetamine; Amphetamines; Cities; Cocaine; Humans; Illicit Drugs; Methamphetamine; Republic of Korea; Substance Abuse Detection; Substance-Related Disorders; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2015 |
Rapid detection of cocaine, benzoylecgonine and methylecgonine in fingerprints using surface mass spectrometry.
Topics: Atmospheric Pressure; Cocaine; Dermatoglyphics; Humans; Mass Spectrometry; Substance Abuse Detection; Surface Properties; Time Factors | 2015 |
Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS/MS and TOF-SIMS imaging.
Topics: Cocaine; Dopamine Uptake Inhibitors; Equipment Design; Hair; Humans; Specimen Handling; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2015 |
A Direct Aqueous Derivatization GSMS Method for Determining Benzoylecgonine Concentrations in Human Urine.
Topics: Cocaine; Forensic Toxicology; Formates; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Narcotics | 2015 |
Cocaine and metabolite concentrations in DBS and venous blood after controlled intravenous cocaine administration.
Topics: Adult; Chromatography, Liquid; Cocaine; Dried Blood Spot Testing; Female; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Male; Mass Spectrometry; Middle Aged; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Environmental concentrations of the cocaine metabolite benzoylecgonine induced sublethal toxicity in the development of plants but not in a zebrafish embryo-larval model.
Topics: Animals; Chlorophyll; Cocaine; DNA, Plant; Embryo, Nonmammalian; Embryonic Development; Ferns; Larva; Mitochondria; Plants; Water Pollutants, Chemical; Zebrafish | 2015 |
LC-MS-MS Method for Stimulants in Wastewater During Football Games.
Topics: Amphetamines; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Cocaine; Football; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Reproducibility of Results; Substance Abuse Detection; Tandem Mass Spectrometry; Universities; Wastewater | 2016 |
Development of magnetic molecularly imprinted polymers for solid phase extraction of cocaine and metabolites in urine before high performance liquid chromatography - tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Ferrosoferric Oxide; Humans; Limit of Detection; Magnetic Phenomena; Methacrylates; Molecular Imprinting; Nitriles; Polyethylene Glycols; Solid Phase Extraction; Tandem Mass Spectrometry; Ultrasonic Waves; Vinyl Compounds | 2016 |
An Acute Butyr-Fentanyl Fatality: A Case Report with Postmortem Concentrations.
Topics: Adult; Analgesics, Opioid; Cocaine; Drug Overdose; Enzyme-Linked Immunosorbent Assay; Fatal Outcome; Fentanyl; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Male; Opioid-Related Disorders; Substance Abuse, Intravenous | 2016 |
New sorbent materials for selective extraction of cocaine and benzoylecgonine from human urine samples.
Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Polymers | 2016 |
Selective determination of cocaine and its metabolite benzoylecgonine in environmental samples by newly developed sorbent materials.
Topics: Cocaine; Models, Molecular; Molecular Conformation; Molecular Imaging; Molecular Imprinting; Polymers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Investigation on the removal of the major cocaine metabolite (benzoylecgonine) in water matrices by UV254/H2O2 process by using a flow microcapillary film array photoreactor as an efficient experimental tool.
Topics: Chromatography, Liquid; Cocaine; Fresh Water; Hydrogen Peroxide; Mass Spectrometry; Oxidation-Reduction; Photolysis; Ultraviolet Rays; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification | 2016 |
Oral fluid cocaine and benzoylecgonine concentrations following controlled intravenous cocaine administration.
Topics: Adult; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Narcotics; Saliva; Substance Abuse Detection; Time Factors | 2016 |
Simple and Sensitive Molecularly Imprinted Polymer - Mn-Doped ZnS Quantum Dots Based Fluorescence Probe for Cocaine and Metabolites Determination in Urine.
Topics: Calibration; Cocaine; Fluorescent Dyes; Humans; Limit of Detection; Manganese; Molecular Imprinting; Polymers; Quantum Dots; Spectrometry, Fluorescence; Substance Abuse Detection; Sulfides; Zinc Compounds | 2016 |
Polypeptide Functional Surface for the Aptamer Immobilization: Electrochemical Cocaine Biosensing.
Topics: Aptamers, Nucleotide; Biosensing Techniques; Cocaine; Electrochemical Techniques; Molecular Structure; Peptides; Surface Properties | 2016 |
Monitoring two transitions by LC-MS/MS may not be sufficient to positively identify benzoylecgonine in patient urine samples.
Topics: Chromatography, Liquid; Cocaine; Humans; Tandem Mass Spectrometry; Urinalysis | 2016 |
Sheath flow SERS for chemical profiling in urine.
Topics: Cocaine; Electrophoresis, Capillary; Humans; Hydrodynamics; Spectrum Analysis, Raman; Urinalysis | 2016 |
Pharmacodynamic effects and relationships to plasma and oral fluid pharmacokinetics after intravenous cocaine administration.
Topics: Administration, Intravenous; Adolescent; Adult; Chromatography, Gas; Cocaine; Cocaine-Related Disorders; Female; Hemodynamics; Humans; Male; Middle Aged; Saliva; Surveys and Questionnaires; Tandem Mass Spectrometry; Young Adult | 2016 |
Substance use in individuals with mild to borderline intellectual disability: A comparison between self-report, collateral-report and biomarker analysis.
Topics: Adult; Alcohol Drinking; Amphetamine-Related Disorders; Amphetamines; Biomarkers; Cocaine; Cocaine-Related Disorders; Cotinine; Dronabinol; Ethanol; Female; Hair; Humans; Intellectual Disability; Male; Marijuana Smoking; Middle Aged; Netherlands; Self Report; Severity of Illness Index; Smoking; Substance Abuse Detection; Substance-Related Disorders; Sweat; Urine; Young Adult | 2017 |
Determination of cocaine and its metabolites in plasma by porous membrane-protected molecularly imprinted polymer micro-solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cocaine; Drug Users; Humans; Molecular Imprinting; Polymers; Porosity; Solid Phase Extraction; Tandem Mass Spectrometry; Time Factors | 2016 |
Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine.
Topics: Animals; Butyrylcholinesterase; Cocaine; Cocaine-Related Disorders; Drug Overdose; Humans; Inactivation, Metabolic; Rats | 2016 |
Occurrence of drugs of abuse in surface water from four Spanish river basins: Spatial and temporal variations and environmental risk assessment.
Topics: Cocaine; Environmental Monitoring; Ephedrine; Geography; Illicit Drugs; Methadone; N-Methyl-3,4-methylenedioxyamphetamine; Pyrrolidines; Risk Assessment; Rivers; Spain; Spatio-Temporal Analysis; Water; Water Pollutants, Chemical | 2016 |
An aptamer folding-based sensory platform decorated with nanoparticles for simple cocaine testing.
Topics: Anesthetics, Local; Aptamers, Nucleotide; Cocaine; Gold; Humans; Limit of Detection; Metal Nanoparticles; Quantum Dots; Substance Abuse Detection | 2017 |
Removal of benzoylecgonine from water matrices through UV254/H2O2 process: Reaction kinetic modeling, ecotoxicity and genotoxicity assessment.
Topics: Animals; Aquatic Organisms; Cocaine; Ecotoxicology; Hydrogen Peroxide; Kinetics; Mutagens; Plants; Ultraviolet Rays; Water; Water Pollutants, Chemical | 2016 |
Behaviour of emerging contaminants in sewage sludge after anaerobic digestion.
Topics: Anaerobiosis; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cocaine; Irbesartan; Mass Spectrometry; Sewage; Tandem Mass Spectrometry; Tetrazoles; Venlafaxine Hydrochloride; Wastewater; Water; Water Pollutants, Chemical | 2016 |
Occurrence of cocaine and benzoylecgonine in drinking and source water in the São Paulo State region, Brazil.
Topics: Brazil; Cocaine; Drinking Water; Environmental Monitoring; Rivers; Water Pollutants, Chemical | 2017 |
The anatomical mummies of Mombello: detection of cocaine, nicotine, and caffeine in the hair of psychiatric patients of the early 20th century.
Topics: Caffeine; Chromatography, High Pressure Liquid; Cocaine; Female; Hair; History, 20th Century; Hospitals, Psychiatric; Humans; Italy; Male; Mass Spectrometry; Mummies; Nicotine | 2017 |
A sensitive assay for urinary cocaine metabolite benzoylecgonine shows more positive results and longer half-lives than those using traditional cut-offs.
Topics: Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Half-Life; Humans; Limit of Detection; Substance Abuse Detection; Tandem Mass Spectrometry | 2017 |
Modified Method for Detection of Benzoylecgonine in Human Urine by GC-MS: Derivatization Using Pentafluoropropanol/Acetic Anhydride.
Topics: Acetic Anhydrides; Cocaine; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Substance Abuse Detection | 2017 |
Monitoring of the stability of cocaine and some metabolites in water and oral fluid by a newly developed CE method.
Topics: Body Fluids; Cocaine; Drug Stability; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Saliva; Temperature; Water | 2017 |
Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease.
Topics: Adult; Biomarkers; Black or African American; Cardiovascular Diseases; Case-Control Studies; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Prevalence; Troponin I | 2017 |
Evaluation of an Automated Reader and Color Interpretation-Based Immunoassays for Multiplexed Drug-of-Abuse Testing in Urine.
Topics: Amphetamine; Automation; Buprenorphine; China; Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Immunoassay; Mass Spectrometry; Methadone; Methamphetamine; Morphine; Sensitivity and Specificity; Substance Abuse Detection | 2017 |
Cocaine use is associated with a higher prevalence of elevated ST2 concentrations.
Topics: Adult; Asymptomatic Diseases; Biomarkers; Biotransformation; Case-Control Studies; Cocaine; Cocaine-Related Disorders; Female; Heart Diseases; Hospitals, General; Humans; Illicit Drugs; Interleukin-1 Receptor-Like 1 Protein; Male; Middle Aged; Retrospective Studies; Risk; Safety-net Providers; San Francisco; Severity of Illness Index; Solubility; Substance Abuse Detection; Toxicokinetics; Up-Regulation | 2017 |
Environmental concentrations of cocaine and its main metabolites modulated antioxidant response and caused cyto-genotoxic effects in zebrafish embryo cells.
Topics: Animals; Antioxidants; Biomarkers; Cocaine; DNA Damage; Embryo, Nonmammalian; Fresh Water; Illicit Drugs; Micronucleus Tests; Oxidation-Reduction; Oxidative Stress; Substance Abuse Detection; Water Pollutants, Chemical; Zebrafish | 2017 |
Illicit drug consumption in school populations measured by wastewater analysis.
Topics: Amphetamine; Cannabinoids; Cannabis; Cocaine; Humans; Illicit Drugs; Italy; Ketamine; Mass Spectrometry; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Substance Abuse Detection; Substance-Related Disorders; Wastewater | 2017 |
Drugged Driving in Wisconsin: Oral Fluid Versus Blood.
Topics: Adolescent; Adult; Aged; Amphetamine; Analgesics, Opioid; Automobile Driving; Benzodiazepines; Cocaine; Driving Under the Influence; Ethanol; Female; Forensic Toxicology; Humans; Illicit Drugs; Male; Methamphetamine; Middle Aged; Morphine; Saliva; Substance Abuse Detection; Wisconsin; Young Adult | 2017 |
Full validation of a method for the determination of drugs of abuse in non-mineralized dental biofilm using liquid chromatography-tandem mass spectrometry and application to postmortem samples.
Topics: Amphetamines; Biofilms; Chromatography, Liquid; Cocaine; Dental Plaque; Humans; Illicit Drugs; Morphine Derivatives; Reproducibility of Results; Tandem Mass Spectrometry | 2018 |
Benzoylecgonine exposure induced oxidative stress and altered swimming behavior and reproduction in Daphnia magna.
Topics: Animals; Antioxidants; Behavior, Animal; Biomarkers; Cocaine; Daphnia; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Reproduction; Swimming; Toxicity Tests, Chronic; Water Pollutants, Chemical | 2018 |
Rapid, Secure Drug Testing Using Fingerprint Development and Paper Spray Mass Spectrometry.
Topics: Cocaine; Dermatoglyphics; Humans; Limit of Detection; Mass Spectrometry; Paper; Saliva; Substance Abuse Detection; Sweat | 2017 |
Exposure to cocaine and its main metabolites altered the protein profile of zebrafish embryos.
Topics: Animals; Cocaine; Embryo, Nonmammalian; Fresh Water; Illicit Drugs; Oxidation-Reduction; Oxidative Stress; Zebrafish; Zebrafish Proteins | 2018 |
Determination of hydroxy metabolites of cocaine in hair samples for proof of consumption.
Topics: Cocaine; Dopamine Uptake Inhibitors; Hair; Humans; Hydroxylation; Illicit Drugs; Limit of Detection; Substance Abuse Detection; Tandem Mass Spectrometry | 2018 |
Efficient extraction method using magnetic carbon nanotubes to analyze cocaine and benzoylecgonine in breast milk by GC/MS.
Topics: Adult; Calibration; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Milk, Human; Nanotubes, Carbon; Solid Phase Extraction | 2017 |
Detection of Cocaine and Metabolites in Bone Following Decomposition Using 2D LC-MS-MS.
Topics: Animals; Bone and Bones; Calibration; Chromatography, Liquid; Cocaine; Humans; Limit of Detection; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2018 |
Wastewater-based epidemiology and enantiomeric profiling for drugs of abuse in South African wastewaters.
Topics: Cocaine; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; South Africa; Substance Abuse Detection; Wastewater; Water Pollutants, Chemical | 2018 |
High-Throughput Monitoring of Cocaine and Its Metabolites in Hair Using Microarrays for Mass Spectrometry and Matrix-Assisted Laser Desorption/Ionization-Tandem Mass Spectrometry.
Topics: Adult; Cocaine; Female; Hair; Humans; Limit of Detection; Male; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2018 |
Estimation of Measurement Uncertainty in Quantitation of Benzoylecgonine (BZE) and 11-nor-Δ9-THC-9-carboxylic acid (THCA).
Topics: Calibration; Cocaine; Dronabinol; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Quality Control; Reference Standards; Reproducibility of Results; Substance Abuse Detection; Uncertainty; United States; United States Department of Defense; Urinalysis | 2018 |
Occurrence of illicit drugs in two wastewater treatment plants in the South of Italy.
Topics: Amphetamine; Amphetamines; Cannabidiol; Cocaine; Dronabinol; Drug Combinations; Humans; Illicit Drugs; Methamphetamine; Pyrrolidines; Sicily; Substance Abuse Detection; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2018 |
Analysis of cocaine adulterants in human brain in cases of drug-related death.
Topics: Brain Chemistry; Cetirizine; Cocaine; Cocaine-Related Disorders; Diltiazem; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyzine; Levamisole; Lidocaine; Narcotics; Phenacetin; Reproducibility of Results; Solid Phase Extraction | 2018 |
Discordant Umbilical Cord Drug Testing Results in Monozygotic Twins.
Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Enzyme-Linked Immunosorbent Assay; Female; Fetal Blood; Humans; Hydromorphone; Illicit Drugs; Infant, Newborn; Maternal-Fetal Exchange; Neonatal Screening; Pregnancy; Pregnancy Complications; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Twins, Monozygotic | 2018 |
Bioavailability and Pharmacokinetics of Oral Cocaine in Humans.
Topics: Administration, Oral; Adult; Biological Availability; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Illicit Drugs; Injections, Intravenous; Male; Metabolic Clearance Rate; Models, Biological; Sex Characteristics; Toxicokinetics | 2018 |
Hair analysis when external contamination is in question: A review of practical approach for the interpretation of results.
Topics: Cocaine; Cocaine-Related Disorders; Equipment Contamination; Forensic Toxicology; Hair; Humans; Narcotics; Specimen Handling; Substance Abuse Detection | 2018 |
Noninvasive Detection of Cocaine and Heroin Use with Single Fingerprints: Determination of an Environmental Cutoff.
Topics: Case-Control Studies; Cocaine; Fingers; Hand Disinfection; Heroin; Humans; Limit of Detection; Morphine Derivatives; Reproducibility of Results; Skin; Substance Abuse Detection; Substance-Related Disorders | 2018 |
Wastewater-based epidemiology generated forensic information: Amphetamine synthesis waste and its impact on a small sewage treatment plant.
Topics: Amphetamine; Chromatography, High Pressure Liquid; Cocaine; Drug Trafficking; Environmental Monitoring; Hazardous Waste; Humans; Illicit Drugs; Mass Spectrometry; Netherlands; Wastewater; Water Pollutants, Chemical | 2018 |
Contaminants of Emerging Concern in Wastewaters in Barbados, West Indies.
Topics: 3,4-Methylenedioxyamphetamine; Androstenedione; Barbados; Caffeine; Chromatography, Liquid; Cocaine; Environmental Monitoring; Estrone; Ibuprofen; N-Methyl-3,4-methylenedioxyamphetamine; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2018 |
A liquid chromatography-tandem mass spectrometry method for the determination of cocaine and metabolites in blood and in dried blood spots collected from postmortem samples and evaluation of the stability over a 3-month period.
Topics: Autopsy; Chromatography, High Pressure Liquid; Cocaine; Dried Blood Spot Testing; Humans; Limit of Detection; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2018 |
TV-1380 attenuates cocaine-induced changes in cardiodynamic parameters in monkeys and reduces the formation of cocaethylene.
Topics: Albumins; Animals; Butyrylcholinesterase; Cocaine; Drug Interactions; Electrocardiography; Ethanol; Female; Heart Rate; Humans; Macaca fascicularis; Male; Recombinant Fusion Proteins; Respiration; Troponin I | 2018 |
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Cocaine; Crack Cocaine; Humans; Illicit Drugs; Liquid-Liquid Extraction; Mass Spectrometry; Reproducibility of Results; Substance Abuse Detection | 2018 |
Occurrence, removal and environmental risk of markers of five drugs of abuse in urban wastewater systems in South Australia.
Topics: Biomarkers; Chromatography, Liquid; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sewage; Solid Phase Extraction; South Australia; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
The Development of Bacterial Carboxylesterase Biological Recognition Elements for Cocaine Detection.
Topics: Bacterial Proteins; Biosensing Techniques; Carboxylesterase; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Cloning, Molecular; Cocaine; Hydrogen-Ion Concentration; Hydrolysis; Recombinant Proteins; Temperature | 2018 |
Presence of Parent Cocaine in the Absence of Benzoylecgonine in Urine.
Topics: Chromatography, Liquid; Cocaine; Cocaine-Related Disorders; Humans; Limit of Detection; Reproducibility of Results; Specimen Handling; Substance Abuse Detection; Tandem Mass Spectrometry | 2018 |
Rapid Determination of Cocaine and Its Metabolite Benzoylecgonine in Hair by LC-MS/MS.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Cocaine; Hair; Humans; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry | 2018 |
A Recombinant Humanized Anticocaine Monoclonal Antibody Alters the Urinary Clearance of Cocaine and Its Metabolites in Rats.
Topics: Animals; Antibodies, Monoclonal, Humanized; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Humans; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renal Elimination; Substance Abuse Detection | 2019 |
Plasma and Urine Levamisole in Clinical Samples Containing Benzoylecgonine: Absence of Aminorex.
Topics: Adult; Aged; Agranulocytosis; Aminorex; Antinematodal Agents; Appetite Depressants; Chromatography, Liquid; Cocaine; Drug Contamination; Female; Half-Life; Humans; Illicit Drugs; Levamisole; Male; Middle Aged; Osmolar Concentration; Substance Abuse Detection; Tandem Mass Spectrometry; Vasculitis; Vasoconstrictor Agents; Young Adult | 2019 |
A laboratory-study on the analytical determination and removal processes of THC-COOH and bezoylecgonine in the activated sludge reactor.
Topics: Adsorption; Biodegradation, Environmental; Cannabis; Chromatography, Liquid; Cocaine; Dronabinol; Sewage; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2019 |
Discrimination between chewing of coca leaves or drinking of coca tea and smoking of "paco" (coca paste) by hair analysis. A preliminary study of possibilities and limitations.
Topics: Acetone; Adolescent; Adult; Biomarkers; Coca; Cocaine; Cocaine-Related Disorders; Female; Hair; Humans; Male; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Smoking; Substance Abuse Detection; Tea; Young Adult | 2019 |
Nails Analysis for Drugs Used in the Context of Chemsex: A Pilot Study.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Dronabinol; Forensic Toxicology; Hair; Humans; Hydroxybutyrates; Illicit Drugs; Nails; Psychotropic Drugs; Solid Phase Extraction; Substance Abuse Detection | 2020 |
Profiling cocaine residues and pyrolytic products in wastewater by mixed-mode liquid chromatography-tandem mass spectrometry.
Topics: Brazil; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Cocaine; Drug Residues; Illicit Drugs; Levamisole; Pyrolysis; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2019 |
Simultaneous determination of cocaine, ecgonine methyl ester, benzoylecgonine, cocaethylene and norcocaine in dried blood spots by ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Topics: Blood Stains; Chromatography, High Pressure Liquid; Cocaine; Hematocrit; Humans; Narcotics; Reproducibility of Results; Specimen Handling; Tandem Mass Spectrometry | 2019 |
Detection of fentanyl and fentanyl analogues in biological samples using liquid chromatography-high resolution mass spectrometry.
Topics: Adult; Analgesics, Opioid; Central Nervous System Depressants; Chromatography, Liquid; Cocaine; Ethanol; Fentanyl; Humans; Mass Spectrometry; Middle Aged; Morphine; Opioid-Related Disorders; Substance Abuse Detection; Young Adult | 2019 |
Simultaneous Determination of Cocaine and Metabolites in Human Plasma Using Solid Phase Micro-Extraction Fiber Tips C18 and UPLC-MS/MS.
Topics: Amines; Chromatography, Liquid; Cocaine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Illicit Drugs; Plasma; Solid Phase Microextraction; Substance Abuse Detection; Tandem Mass Spectrometry | 2020 |
Disposable electrochemical immunosensor array for the multiplexed detection of the drug metabolites morphine, tetrahydrocannabinol and benzoylecgonine.
Topics: Antibodies; Cocaine; Dronabinol; Electrochemical Techniques; Gold; Humans; Illicit Drugs; Immobilized Proteins; Immunoassay; Limit of Detection; Metal Nanoparticles; Morphine; Substance Abuse Detection | 2019 |
AEME production in cocaine positive hair after thermal hair treatment.
Topics: Biomarkers; Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Hair Preparations; Humans; In Vitro Techniques; Narcotics; Substance Abuse Detection | 2019 |
Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry.
Topics: Amphetamine; Cocaine; Cotton Fiber; Diazepam; Dried Blood Spot Testing; Gossypium; Humans; Limit of Detection; Mass Spectrometry; Methamphetamine; Sepharose; Solid Phase Extraction; Specimen Handling | 2019 |
A comparison of trends in wastewater-based data and traditional epidemiological indicators of stimulant consumption in three locations.
Topics: Amphetamine; Cocaine; Data Collection; Humans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Netherlands; Norway; Queensland; Substance Abuse Detection; Wastewater; Wastewater-Based Epidemiological Monitoring | 2020 |
Spatio-temporal assessment of illicit drug use at large scale: evidence from 7 years of international wastewater monitoring.
Topics: Amphetamine; Chromatography, Liquid; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Internationality; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Spatio-Temporal Analysis; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater | 2020 |
Structural analysis of free and liganded forms of the Fab fragment of a high-affinity anti-cocaine antibody, h2E2.
Topics: Amino Acid Sequence; Antibodies; Cocaine; Crystallization; Crystallography, X-Ray; Humans; Hydrogen Bonding; Immunoglobulin Fab Fragments; Ligands; Protein Domains; Recombinant Proteins | 2019 |
A Retrospective of Prevalence of Drugs of Abuse by Hair Analysis in Shanghai using LC-MS-MS.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Amphetamines; Central Nervous System Stimulants; China; Chromatography, Liquid; Cocaine; Female; Hair; Hair Analysis; Humans; Illicit Drugs; Male; Methamphetamine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Prevalence; Retrospective Studies; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry | 2020 |
Stability and Degradation Pathways of Different Psychoactive Drugs in Neat and in Buffered Oral Fluid.
Topics: Amphetamine; Cocaine; Codeine; Drug Stability; Forensic Toxicology; Illicit Drugs; Methamphetamine; Morphine; Morphine Derivatives; N-Methyl-3,4-methylenedioxyamphetamine; Psychotropic Drugs; Specimen Handling; Substance Abuse Detection | 2020 |
On the relevance of cocaine detection in a fingerprint.
Topics: Cocaine; Cocaine-Related Disorders; Dermatoglyphics; Forensic Toxicology; Hand Disinfection; Humans; Ireland; Mass Spectrometry; Sensitivity and Specificity; Skin; Substance Abuse Detection; Time Factors | 2020 |
Fiber spray ionization mass spectrometry in forensic chemistry: A screening of drugs of abuse and direct determination of cocaine in urine.
Topics: Analgesics, Opioid; Cannabinoids; Cannabis; Cocaine; Forensic Sciences; Humans; Illicit Drugs; Limit of Detection; Mass Spectrometry; N-Methyl-3,4-methylenedioxyamphetamine; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tablets | 2020 |
Blood and Plasma Volumetric Absorptive Microsampling (VAMS) Coupled to LC-MS/MS for the Forensic Assessment of Cocaine Consumption.
Topics: Blood Specimen Collection; Chromatography, Liquid; Cocaine; Forensic Medicine; Humans; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |
Do dried blood spots (DBS) have the potential to support result management processes in routine sports drug testing?
Topics: Cocaine; Doping in Sports; Dried Blood Spot Testing; Humans; Performance-Enhancing Substances; Pharmaceutical Preparations; Pilot Projects; Prednisolone; Prednisone; Reference Standards; Sports; Substance Abuse Detection | 2020 |
Effects of single and combined exposure to cocaine and benzoylecgonine on the oxidative status of Mytilus galloprovincialis.
Topics: Animals; Cocaine; Drug Synergism; Gastrointestinal Tract; Gills; Illicit Drugs; Lipid Peroxidation; Mytilus; Oxidative Stress; Reactive Oxygen Species; Water Pollutants, Chemical | 2020 |
Mussels get higher: A study on the occurrence of cocaine and benzoylecgonine in seawater, sediment and mussels from a subtropical ecosystem (Santos Bay, Brazil).
Topics: Animals; Bays; Bivalvia; Brazil; Cocaine; Ecosystem; Environmental Monitoring; Humans; Seafood; Seawater; Water Pollutants, Chemical | 2021 |
Stability of Cocaine Compounds in Biological Fluids During Post-Analytical Sample Storage.
Topics: Body Fluids; Chromatography, High Pressure Liquid; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Narcotics; Specimen Handling; Temperature | 2020 |
The analytical performance of six urine drug screens on cobas 6000 and ARCHITECT i2000 compared to LC-MS/MS gold standard.
Topics: Amphetamine; Chromatography, High Pressure Liquid; Cocaine; Diagnostic Errors; Dronabinol; Humans; Immunoassay; Opiate Alkaloids; Oxycodone; Predictive Value of Tests; Pyrrolidines; Substance Abuse Detection; Tandem Mass Spectrometry | 2021 |
Evaluation of the diagnostic performance of an oral fluid screening test device for substance abuse at traffic controls.
Topics: Amphetamines; Cocaine; Data Accuracy; Driving Under the Influence; Dronabinol; Equipment Failure Analysis; Female; Forensic Toxicology; Humans; Illicit Drugs; Immunoassay; Male; Methamphetamine; Morphine; Nordazepam; Plasma; Predictive Value of Tests; Saliva; Substance Abuse Detection; Tandem Mass Spectrometry | 2021 |
Positivity to Cocaine and/or Benzoylecgonine in Confirmation Analyses for On-Road Tests in Spain.
Topics: Cocaine; Cocaine-Related Disorders; Female; Humans; Spain; Substance Abuse Detection | 2021 |
Simplified miniaturized analytical set-up based on molecularly imprinted polymer directly coupled to UV detection for the determination of benzoylecgonine in urine.
Topics: Chromatography, High Pressure Liquid; Cocaine; Humans; Molecular Imprinting; Molecularly Imprinted Polymers; Reproducibility of Results; Solid Phase Extraction | 2021 |
Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase.
Topics: Cocaine; Hydrolases; Models, Molecular; Molecular Structure | 2021 |
First report on the occurrence of pharmaceuticals and cocaine in the coastal waters of Santa Catarina, Brazil, and its related ecological risk assessment.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Cosmetics; Diclofenac; Ecosystem; Environmental Monitoring; Humans; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Sewage; Solid Waste; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical | 2022 |
Differential biochemical and behavioral responses induced by cocaine and benzoylecgonine exposure to the red swamp crayfish Procambarus clarkii.
Topics: Acetylcholinesterase; Animals; Astacoidea; Cocaine; Oxidative Stress; Water Pollutants, Chemical | 2022 |
Occurrence, ecological risk assessment and prioritization of pharmaceuticals and abuse drugs in estuarine waters along the São Paulo coast, Brazil.
Topics: Acetaminophen; Atenolol; Brazil; Caffeine; Carbamazepine; Chromatography, Liquid; Cocaine; Diclofenac; Ecosystem; Environmental Monitoring; Furosemide; Illicit Drugs; Losartan; Orphenadrine; Pharmaceutical Preparations; Risk Assessment; Rivers; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2022 |
Postmortem redistribution of cocaine and its metabolites, benzoylecgonine and ecgonine methyl ester in humans: Important variables that might be influencing the central blood / peripheral blood ratio.
Topics: Autopsy; Cocaine; Humans; Postmortem Changes | 2023 |
Wastewater analysis for new psychoactive substances and cocaine and cannabis in a Northern Ireland Prison.
Topics: Cannabis; Central Nervous System Agents; Cocaine; Codeine; Hallucinogens; Northern Ireland; Prisons; Substance Abuse Detection; Wastewater; Water Pollutants, Chemical | 2023 |