cocaine has been researched along with benzoxazoles in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 25 (83.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Acara, M; Rennick, B | 1 |
| Boutrel, B; de Lecea, L; Kenny, PJ; Koob, GF; Markou, A; Martin-Fardon, R; Specio, SE | 1 |
| Bonci, A; Borgland, SL; Fields, HL; Sarti, F; Taha, SA | 1 |
| Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK | 1 |
| Aston-Jones, G; Smith, RJ; Tahsili-Fahadan, P | 1 |
| Aston-Jones, G; See, RE; Smith, RJ | 1 |
| DiLeone, RJ; Guarnieri, DJ; Sharf, R; Taylor, JR | 1 |
| Brookshire, BR; España, RA; Jones, SR; Locke, JL; Oleson, EB; Roberts, DC | 1 |
| Garcés-Ramírez, L; Green, JL; Hiranita, T; Katz, JL; Kopajtic, TA; McCurdy, CR; Mereu, M; Mesangeau, C; Narayanan, S; Tanda, G; Thomas, AM | 1 |
| Halbout, B; Heidbreder, C; Hutcheson, DM; Quarta, D; Rigal, A; Valerio, E | 1 |
| Charnley, JL; Dayas, CV; James, MH; Jones, E; Levi, EM; Smith, DW; Yeoh, JW | 1 |
| Avery, BA; Kaushal, N; Matsumoto, RR; McCurdy, CR; Narayanan, S; Robson, MJ; Vinnakota, H | 1 |
| Gaál, J; Gardner, EL; Li, J; Li, X; Peng, XQ; Song, R; Su, RB; Wu, N; Xi, ZX; Yang, RF | 1 |
| Fish, EW; Jarrett, TM; Malanga, CJ; McGuigan, MM; Riday, TT; Robinson, JE | 1 |
| Aston-Jones, G; Mahler, SV; Smith, RJ | 1 |
| Aston-Jones, GS; Sartor, GC | 1 |
| Aston-Jones, G; Do, PH; See, RE; Smith, RJ; Zhou, L | 1 |
| Gardner, EL; Li, J; Peng, XQ; Song, R; Su, RB; Xi, ZX; Yang, RF; Zhang, HY | 1 |
| Bi, GH; Gardner, EL; Li, J; Song, R; Xi, ZX; Yang, RF; Zhang, HY | 1 |
| Martin-Fardon, R; Weiss, F | 1 |
| Chen, Y; Li, J; Song, R; Wu, N; Yang, RF | 1 |
| España, RA; Prince, CD; Rau, AR; Yorgason, JT | 1 |
| Bernstein, DL; Brodnik, ZD; España, RA; Prince, CD | 1 |
| Kerr, TM; Martin-Fardon, R; Matzeu, A; Weiss, F | 1 |
| Herman, MA; Koob, GF; Roberto, M; Schmeichel, BE | 1 |
| Brailoiu, E; Connelly, KL; Gentile, TA; Muschamp, JW; Simmons, SJ; Watson, MN; Zhang, Y | 1 |
| Evans, SM; Foltin, RW | 1 |
| Aston-Jones, G; Bowrey, HE; James, MH; Koll, NE; Stopper, CM; Zimmer, BA | 1 |
| Aston-Jones, G; Bowrey, HE; James, MH; Stopper, CM | 1 |
| Cui, C; Jia, M; Li, Y; Ma, H; Miao, D; Wu, L; Yang, M | 1 |
30 other study(ies) available for cocaine and benzoxazoles
| Article | Year |
|---|---|
Renal tubular transport of acetylcholine and atropine: enhancement an inhibition.
Topics: Acetates; Acetylcholine; Alkenes; Animals; Atropine; Benzoxazoles; Biological Transport, Active; Carbon Isotopes; Chickens; Choline; Cholinesterase Inhibitors; Chromatography, Paper; Cocaine; Coloring Agents; Depression, Chemical; Electrophoresis; Female; Kidney Tubules; Kinetics; Paraoxon; Physostigmine; Quinine; Stimulation, Chemical; Tritium | 1972 |
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior.
Topics: Analysis of Variance; Animals; Behavior, Addictive; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Intracellular Signaling Peptides and Proteins; Male; Models, Statistical; Naphthyridines; Neuropeptides; Orexins; Rats; Rats, Wistar; Reward; Self Administration; Time Factors; Urea | 2005 |
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Behavior, Animal; Benzoxazoles; Calcium Channel Blockers; Cocaine; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lysine; Male; Motor Activity; N-Methylaspartate; Naphthyridines; Neuronal Plasticity; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Protein Kinase C; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Thionucleotides; Time Factors; Tyrosine 3-Monooxygenase; Urea; Ventral Tegmental Area | 2006 |
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides.
Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors | 2010 |
Orexin/hypocretin is necessary for context-driven cocaine-seeking.
Topics: Analysis of Variance; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement, Psychology; Self Administration; Time Factors; Urea | 2010 |
Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.
Topics: Animals; Behavior, Addictive; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement, Psychology; Signal Transduction; Urea | 2009 |
Orexin mediates morphine place preference, but not morphine-induced hyperactivity or sensitization.
Topics: Animals; Benzoxazoles; Central Nervous System Agents; Cocaine; Conditioning, Classical; Dopamine Uptake Inhibitors; Female; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Mutation; Naphthyridines; Narcotics; Neuropeptides; Orexin Receptors; Orexins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Space Perception; Time Factors; Urea | 2010 |
The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system.
Topics: Animals; Benzoxazoles; Cocaine; Dopamine; Electrochemistry; Intracellular Signaling Peptides and Proteins; Limbic System; Male; Mesencephalon; Mice; Microdialysis; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Signal Transduction; Urea | 2010 |
Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis.
Topics: Animals; Benzoxazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Ethylenediamines; Guanidines; Male; Microdialysis; Morpholines; Nucleus Accumbens; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Synaptic Transmission | 2011 |
Orexin-1 receptor antagonist SB-334867 reduces the acquisition and expression of cocaine-conditioned reinforcement and the expression of amphetamine-conditioned reward.
Topics: Animals; Behavior, Animal; Benzoxazoles; Cocaine; Conditioning, Operant; Cues; Dextroamphetamine; Discrimination Learning; Male; Naphthyridines; Orexin Receptors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement Schedule; Reward; Self Administration; Urea | 2011 |
Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking.
Topics: Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Motor Activity; Naphthyridines; Orexin Receptors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Thalamus; Urea; Ventral Tegmental Area | 2011 |
Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents.
Topics: Administration, Oral; Animals; Benzoxazoles; Cocaine; Cytochrome P-450 Enzyme System; Drug Interactions; Half-Life; Injections, Intraperitoneal; Ligands; Male; Mice; Motor Activity; Piperazines; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT2; Receptors, sigma; Seizures | 2011 |
YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice.
Topics: Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluorenes; Guanosine 5'-O-(3-Thiotriphosphate); Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nitriles; Piperazines; Quinpirole; Radioligand Assay; Random Allocation; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Reinforcement, Psychology; Reward; Self Administration; Sucrose; Tetrahydroisoquinolines | 2012 |
Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice.
Topics: Animals; Benzoxazoles; Brain; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Male; Mice; Motor Activity; Naphthyridines; Orexin Receptors; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reinforcement Schedule; Reward; Self Administration; Urea | 2012 |
Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoxazoles; Cocaine; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide; Self Administration; Signal Transduction; Urea; Ventral Tegmental Area | 2013 |
A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference.
Topics: Animals; Baclofen; Benzoxazoles; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Hypothalamus; Intracellular Signaling Peptides and Proteins; Male; Microinjections; Morpholinos; Muscimol; Naphthyridines; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neurons; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley; Septum of Brain; Urea | 2012 |
Repeated orexin 1 receptor antagonism effects on cocaine seeking in rats.
Topics: Animals; Benzoxazoles; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Male; Naphthyridines; Orexin Receptors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Urea | 2012 |
Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice.
Topics: Animals; Benzoxazoles; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperazines; Receptors, Dopamine D3 | 2013 |
Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Electric Stimulation; Male; Piperazines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Recurrence; Reward | 2014 |
Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Reward; Self Administration; Sweetening Agents; Urea | 2014 |
A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine self-administration and relapse to drug-seeking behaviour in rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; Cocaine; Cocaine-Related Disorders; Dopamine Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Male; Methamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D3; Recurrence; Reinforcement, Psychology; Self Administration | 2014 |
Hypocretin/Orexin regulation of dopamine signaling and cocaine self-administration is mediated predominantly by hypocretin receptor 1.
Topics: Analysis of Variance; Animals; Benzoxazoles; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemical Techniques; Intracellular Signaling Peptides and Proteins; Male; Naphthyridines; Neuropeptides; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Rats; Rats, Sprague-Dawley; Self Administration; Signal Transduction; Urea | 2015 |
Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep.
Topics: Animals; Appetitive Behavior; Benzoxazoles; Brain; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Hypnotics and Sedatives; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration; Sleep; Urea | 2015 |
Orexin-A/Hypocretin-1 Mediates Cocaine-Seeking Behavior in the Posterior Paraventricular Nucleus of the Thalamus via Orexin/Hypocretin Receptor-2.
Topics: Animals; Benzoxazoles; Cocaine; Drug Interactions; Drug-Seeking Behavior; Extinction, Psychological; Isoquinolines; Male; Naphthyridines; Orexin Receptors; Orexins; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Wistar; Urea | 2016 |
Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats.
Topics: Animals; Benzoxazoles; Central Amygdaloid Nucleus; Cocaine; Drug-Seeking Behavior; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Stress, Psychological; Urea | 2017 |
Effects of Suvorexant, a Dual Orexin/Hypocretin Receptor Antagonist, on Impulsive Behavior Associated with Cocaine.
Topics: Animals; Azepines; Benzoxazoles; Choice Behavior; Cocaine; Delay Discounting; Impulsive Behavior; Isoquinolines; Male; Microinjections; Naphthyridines; Orexin Receptor Antagonists; Orexins; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Triazoles; Urea; Ventral Tegmental Area | 2018 |
Hypocretin/orexin antagonists decrease cocaine self-administration by female rhesus monkeys.
Topics: Animals; Behavior, Addictive; Benzoxazoles; Central Nervous System Stimulants; Cocaine; Dose-Response Relationship, Drug; Female; Macaca mulatta; Naphthyridines; Orexins; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Urea | 2018 |
Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats.
Topics: Animals; Benzoxazoles; Cell Count; Cocaine; Drug-Seeking Behavior; Extinction, Psychological; Gene Knockdown Techniques; Hypothalamic Area, Lateral; Hypothalamic Hormones; Male; Melanins; Microinjections; Morpholinos; Motivation; Naphthyridines; Neurons; Orexins; Pituitary Hormones; Rats; Self Administration; Urea | 2019 |
Demand elasticity predicts addiction endophenotypes and the therapeutic efficacy of an orexin/hypocretin-1 receptor antagonist in rats.
Topics: Animals; Behavior, Addictive; Benzoxazoles; Cocaine; Dose-Response Relationship, Drug; Endophenotypes; Forecasting; Male; Motivation; Naphthyridines; Orexin Receptor Antagonists; Orexin Receptors; Rats; Rats, Sprague-Dawley; Self Administration; Treatment Outcome; Urea | 2019 |
The role of the nucleus accumbens OXR1 in cocaine-induced locomotor sensitization.
Topics: Animals; Behavior, Animal; Benzoxazoles; Central Nervous System Sensitization; Cocaine; Dopamine Uptake Inhibitors; Locomotion; Male; Mitochondrial Proteins; Naphthyridines; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Urea | 2020 |